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Wyszukujesz frazę ""6-Aminonicotinamide"" wg kryterium: Temat

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Wyświetlanie 1-20 z 176
Tytuł:
Variation in pentose phosphate pathway-associated metabolism dictates cytotoxicity outcomes determined by tetrazolium reduction assays.
Autorzy:
Coyle JP; HELD/ACIB, National Institute for Occupational Safety and Health, Morgantown, WV, USA. .; Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 1095 Willowdale Rd., Morgantown, WV, 26505, USA. .
Johnson C; HELD/ACIB, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Jensen J; Department of Environmental Health, Harvard University, Boston, MA, USA.
Farcas M; HELD/ACIB, National Institute for Occupational Safety and Health, Morgantown, WV, USA.; Department of Pharmaceutical Sciences, West Virginia University, Morgantown, WV, USA.
Derk R; HELD/ACIB, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Stueckle TA; HELD/ACIB, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Kornberg TG; HELD/ACIB, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Rojanasakul Y; Department of Pharmaceutical Sciences, West Virginia University, Morgantown, WV, USA.
Rojanasakul LW; HELD/ACIB, National Institute for Occupational Safety and Health, Morgantown, WV, USA. .; Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 1095 Willowdale Rd., Morgantown, WV, 26505, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 May 22; Vol. 13 (1), pp. 8220. Date of Electronic Publication: 2023 May 22.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Pentose Phosphate Pathway*
6-Aminonicotinamide*
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Redox state affects fecundity and insecticide susceptibility in Anopheles gambiae.
Autorzy:
Champion CJ; Department of Biology, New Mexico State University, Las Cruces, USA.
Xu J; Department of Biology, New Mexico State University, Las Cruces, USA. .
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Źródło:
Scientific reports [Sci Rep] 2018 Aug 29; Vol. 8 (1), pp. 13054. Date of Electronic Publication: 2018 Aug 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Fertility*
Anopheles/*drug effects
Anopheles/*physiology
Insecticides/*pharmacology
Metabolism/*drug effects
6-Aminonicotinamide/administration & dosage ; Animals ; DDT/administration & dosage ; DDT/pharmacology ; Enzyme Inhibitors/administration & dosage ; Glutathione/analysis ; Insecticides/administration & dosage ; Intestines/chemistry ; Metabolomics ; NADP/metabolism ; Oxidants/administration & dosage ; Oxidation-Reduction ; Paraquat/administration & dosage ; Protein Carbonylation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A metabolism targeting three-pronged attack significantly attenuates breast cancer stem cell related markers toward therapeutic application
Autorzy:
Pegah Farhadi
Shiva Irani
Mohammadreza Gholami
Kamran Mansouri
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Temat:
Breast cancer stem cells
Glycolysis
2-deoxyglucose
6-aminonicotinamide
Doxycycline
Therapeutics. Pharmacology
RM1-950
Źródło:
Biomedicine & Pharmacotherapy, Vol 161, Iss , Pp 114496- (2023)
Opis pliku:
electronic resource
Relacje:
http://www.sciencedirect.com/science/article/pii/S0753332223002846; https://doaj.org/toc/0753-3322
Dostęp URL:
https://doaj.org/article/a4f5bd5f42a74c8e8743ca3d2ae5a914  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Multiple myeloma acquires resistance to EGFR inhibitor via induction of pentose phosphate pathway.
Autorzy:
Chen Y; Department of Haematology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Huang R; Department of Haematology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Ding J; Department of Haematology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Ji D; Department of Haematology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Song B; Department of Haematology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Yuan L; Department of Haematology, Jiangxi Academy of Medical Science, Nanchang 330006, China.
Chang H; Department of Haematology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Chen G; Department of Haematology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
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Źródło:
Scientific reports [Sci Rep] 2015 Apr 20; Vol. 5, pp. 9925. Date of Electronic Publication: 2015 Apr 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Proliferation/*drug effects
ErbB Receptors/*antagonists & inhibitors
Pentose Phosphate Pathway/*drug effects
Protein Kinase Inhibitors/*pharmacology
6-Aminonicotinamide/pharmacology ; Afatinib ; Cell Line, Tumor ; Drug Resistance, Neoplasm/drug effects ; Drug Synergism ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Gefitinib ; Glucose/metabolism ; Humans ; Metabolome/drug effects ; Multiple Myeloma/drug therapy ; Multiple Myeloma/metabolism ; Multiple Myeloma/pathology ; Oxygen/metabolism ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins B-raf/metabolism ; Quinazolines/pharmacology ; Quinazolines/therapeutic use ; RNA, Small Interfering/metabolism ; Receptor, ErbB-2/antagonists & inhibitors ; Receptor, ErbB-2/genetics ; Receptor, ErbB-2/metabolism ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; ras Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prostaglandin E₂ is critical for the development of niacin-deficiency-induced photosensitivity via ROS production.
Autorzy:
Sugita K; 1] Department of Dermatology, University of Occupational and Environmental Health, Kitakyushu, Japan [2] Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ikenouchi-Sugita A
Nakayama Y
Yoshioka H
Nomura T
Sakabe J
Nakahigashi K
Kuroda E
Uematsu S
Nakamura J
Akira S
Nakamura M
Narumiya S
Miyachi Y
Tokura Y
Kabashima K
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Źródło:
Scientific reports [Sci Rep] 2013 Oct 17; Vol. 3, pp. 2973. Date of Electronic Publication: 2013 Oct 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dinoprostone/*metabolism
Niacin/*deficiency
Photosensitivity Disorders/*metabolism
Reactive Oxygen Species/*metabolism
6-Aminonicotinamide/pharmacology ; Animals ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism ; Cyclooxygenase 2 Inhibitors/pharmacology ; Dermatitis/etiology ; Dermatitis/metabolism ; Dermatitis/pathology ; Disease Models, Animal ; Female ; Gene Expression ; Humans ; Mice ; Niacin/antagonists & inhibitors ; Photosensitivity Disorders/etiology ; Photosensitivity Disorders/pathology ; Signal Transduction/drug effects ; Ultraviolet Rays/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Metabolomics Analysis Discovers Estrogen Altering Cell Proliferation via the Pentose Phosphate Pathway in Infertility Patient Endometria
Autorzy:
Yingxin Zheng
Yuemeng Zhu
Ting Zhuge
Bin Li
Chao Gu
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Temat:
metabolomics
estrogen treatment
hysteroscopy
pentose phosphate pathway
6-aminonicotinamide
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Źródło:
Frontiers in Endocrinology, Vol 12 (2021)
Opis pliku:
electronic resource
Relacje:
https://www.frontiersin.org/articles/10.3389/fendo.2021.791174/full; https://doaj.org/toc/1664-2392
Dostęp URL:
https://doaj.org/article/b9c6876589074ba0a35e5557b12cb184  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
2-Deoxy-D-glucose and 6-aminonicotinamide-mediated Nrf2 down regulation leads to radiosensitization of malignant cells via abrogation of GSH-mediated defense.
Autorzy:
Sharma PK; Institute of Nuclear Medicine and Allied Sciences, Defence Research & Development Organization, Delhi, India.
Varshney R
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Źródło:
Free radical research [Free Radic Res] 2012 Dec; Vol. 46 (12), pp. 1446-57. Date of Electronic Publication: 2012 Oct 01.
Typ publikacji:
Journal Article
MeSH Terms:
6-Aminonicotinamide/*pharmacology
Carcinoma, Squamous Cell/*pathology
Deoxyglucose/*pharmacology
Glioma/*pathology
Glutathione/*metabolism
Head and Neck Neoplasms/*pathology
NF-E2-Related Factor 2/*metabolism
Antimetabolites/pharmacology ; Antineoplastic Combined Chemotherapy Protocols ; Apoptosis/drug effects ; Blotting, Western ; Carcinoma, Squamous Cell/drug therapy ; Carcinoma, Squamous Cell/radiotherapy ; Cell Proliferation/drug effects ; Down-Regulation ; Glioma/drug therapy ; Glioma/radiotherapy ; Head and Neck Neoplasms/drug therapy ; Head and Neck Neoplasms/radiotherapy ; Humans ; NF-E2-Related Factor 2/genetics ; Protein Transport/drug effects ; RNA, Messenger/genetics ; Radiation-Sensitizing Agents/pharmacology ; Reactive Oxygen Species/metabolism ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction ; Teratogens/pharmacology ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Glucose-6-phosphate dehydrogenase and NADPH redox regulates cardiac myocyte L-type calcium channel activity and myocardial contractile function.
Autorzy:
Rawat DK; Department of Biochemistry and Molecular Biology, University of South Alabama, Mobile, Alabama, United States of America.
Hecker P
Watanabe M
Chettimada S
Levy RJ
Okada T
Edwards JG
Gupte SA
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (10), pp. e45365. Date of Electronic Publication: 2012 Oct 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Calcium Channels, L-Type/*metabolism
Glucosephosphate Dehydrogenase/*physiology
Myocardial Contraction/*drug effects
NADP/*physiology
6-Aminonicotinamide/pharmacology ; Animals ; Calcium Channels, L-Type/drug effects ; Echocardiography ; Glucosephosphate Dehydrogenase Deficiency/metabolism ; Male ; Mice ; Myocytes, Cardiac/physiology ; Pentose Phosphate Pathway/physiology ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
JC virus T-antigen regulates glucose metabolic pathways in brain tumor cells.
Autorzy:
Noch E; Department of Neuroscience and Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America.
Sariyer IK
Gordon J
Khalili K
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (4), pp. e35054. Date of Electronic Publication: 2012 Apr 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Antigens, Viral, Tumor/*metabolism
Brain Neoplasms/*metabolism
Glioblastoma/*metabolism
Glucose/*metabolism
JC Virus/*metabolism
Medulloblastoma/*metabolism
6-Aminonicotinamide/pharmacology ; Animals ; Antigens, Viral, Tumor/analysis ; Antimetabolites/pharmacology ; Brain Neoplasms/drug therapy ; Brain Neoplasms/virology ; Cell Cycle Checkpoints/drug effects ; Cricetinae ; Cyclic AMP-Dependent Protein Kinases/antagonists & inhibitors ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Deoxyglucose/pharmacology ; Down-Regulation ; Glioblastoma/drug therapy ; Glioblastoma/virology ; Glycolysis/drug effects ; Hexokinase/biosynthesis ; Humans ; JC Virus/drug effects ; Medulloblastoma/drug therapy ; Medulloblastoma/virology ; Metabolic Networks and Pathways/drug effects ; Mice ; Oxythiamine/pharmacology ; Pentose Phosphate Pathway/drug effects ; Reactive Oxygen Species/metabolism ; Transaldolase/biosynthesis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Glucose regulated protein 78 prompts scavenger receptor A-mediated secretion of tumor necrosis factor-α by RAW 264.7 cells.
Autorzy:
Gao S; Atherosclerosis Research Center, Institute of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China.
Zhong X
Ben J
Zhu X
Zheng Y
Zhuang Y
Bai H
Jiang L
Chen Y
Ji Y
Chen Q
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2009 Sep; Vol. 36 (9), pp. 940-4. Date of Electronic Publication: 2009 Mar 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Heat-Shock Proteins/*metabolism
Macrophages/*metabolism
Scavenger Receptors, Class A/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
6-Aminonicotinamide/pharmacology ; Animals ; Cell Line ; Chromones/pharmacology ; Dose-Response Relationship, Drug ; Endoplasmic Reticulum Chaperone BiP ; Endoplasmic Reticulum Stress ; Flavonoids/pharmacology ; Lipoproteins, LDL/metabolism ; MAP Kinase Kinase Kinases/antagonists & inhibitors ; MAP Kinase Kinase Kinases/metabolism ; Macrophages/drug effects ; Macrophages/immunology ; Mice ; Morpholines/pharmacology ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; Time Factors ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Radiosensitization by 6-aminonicotinamide and 2-deoxy-D-glucose in human cancer cells.
Autorzy:
Varshney R; Institute of Nuclear Medicine & Allied Sciences, Delhi, India. />Dwarakanath B
Jain V
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Źródło:
International journal of radiation biology [Int J Radiat Biol] 2005 May; Vol. 81 (5), pp. 397-408.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
6-Aminonicotinamide/*pharmacology
Antimetabolites/*pharmacology
Brain Neoplasms/*pathology
Carcinoma, Squamous Cell/*pathology
Deoxyglucose/*pharmacology
Glioma/*pathology
Radiation-Sensitizing Agents/*pharmacology
Teratogens/*pharmacology
Apoptosis ; Cell Death ; Cell Proliferation ; DNA Damage ; Humans ; Kinetics ; Radiation Tolerance ; S Phase ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Evaluation of Xenopus tropicalis as an alternative test organism for frog embryo teratogenesis assay--Xenopus (FETAX).
Autorzy:
Song MO; National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
Fort DJ
McLaughlin DL
Rogers RL
Thomas JH
Buzzard BO
Noll AM
Myers NK
Pokaż więcej
Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2003 Aug; Vol. 26 (3), pp. 177-89.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Abnormalities, Drug-Induced/*embryology
Teratogens/*toxicity
Toxicity Tests/*methods
Xenopus/*embryology
6-Aminonicotinamide/toxicity ; Abnormalities, Drug-Induced/etiology ; Animals ; Embryo, Nonmammalian/abnormalities ; Embryo, Nonmammalian/drug effects ; Isoniazid/toxicity ; Methotrexate/toxicity ; Xenopus laevis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Energy metabolism and cerebral blood flow during cytotoxic brain edema induced by 6-aminonicotinamide
Autorzy:
Kurita, Daisaku
Haida, M.
Shinohara, Y.
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Źródło:
Brain Edema XII : Proceedings of the 12th International Symposium, Hakone, Japan, November 10–13, 2002. 86:41-44
Książka elektroniczna
Szczegóły
Wyświetlanie 1-20 z 176

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