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Tytuł :
Ameliorative effect of N-acetylcysteine against glyphosate-induced hepatotoxicity in adult male albino rats: histopathological, biochemical, and molecular studies.
Autorzy :
Hashim AR; Cytology and Histology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Bashir DW; Cytology and Histology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt. .
Yasin NAE; Cytology and Histology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Galal MK; Biochemistry and Chemistry of Nutrition Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
M ES; Cytology and Histology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2021 Aug; Vol. 28 (31), pp. 42275-42289. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji :
Journal Article
MeSH Terms :
Acetylcysteine*/metabolism
Acetylcysteine*/pharmacology
Chemical and Drug Induced Liver Injury*/metabolism
Chemical and Drug Induced Liver Injury*/prevention & control
Animals ; Antioxidants/metabolism ; Glycine/analogs & derivatives ; Liver/metabolism ; Male ; Oxidative Stress ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
N-acetylcysteine reduces addiction-like behaviour towards high-fat high-sugar food in diet-induced obese rats.
Autorzy :
Sketriene D; The Florey Institute of Neuroscience and Mental Health, Mental Health Research Theme, Parkville/Melbourne, Victoria, Australia.; The Florey Department of Neuroscience and Mental Health, University of Melbourne, Parkville/Melbourne, Victoria, Australia.
Battista D; The Florey Institute of Neuroscience and Mental Health, Mental Health Research Theme, Parkville/Melbourne, Victoria, Australia.
Perry CJ; The Florey Institute of Neuroscience and Mental Health, Mental Health Research Theme, Parkville/Melbourne, Victoria, Australia.
Sumithran P; Department of Medicine (Austin), University of Melbourne, Melbourne, Victoria, Australia.; Department of Endocrinology, Austin Health, Heidelberg, Victoria, Australia.
Lawrence AJ; The Florey Institute of Neuroscience and Mental Health, Mental Health Research Theme, Parkville/Melbourne, Victoria, Australia.
Brown RM; The Florey Institute of Neuroscience and Mental Health, Mental Health Research Theme, Parkville/Melbourne, Victoria, Australia.; The Florey Department of Neuroscience and Mental Health, University of Melbourne, Parkville/Melbourne, Victoria, Australia.
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Źródło :
The European journal of neuroscience [Eur J Neurosci] 2021 Aug; Vol. 54 (3), pp. 4877-4887. Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcysteine*/pharmacology
Acetylcysteine*/therapeutic use
Sugars*
Animals ; Diet, High-Fat/adverse effects ; Male ; Obesity/drug therapy ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
NAC antagonizes arsenic-induced neurotoxicity through TMEM179 by inhibiting oxidative stress in Oli-neu cells.
Autorzy :
He Z; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China.
Zhang Y; School of Medicine, Guangxi University, 530004, Nanning, Guangxi Zhuang Autonomous Region, China.
Zhang H; School of Medicine, Guangxi University, 530004, Nanning, Guangxi Zhuang Autonomous Region, China.
Zhou C; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China.
Ma Q; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China.
Deng P; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China.
Lu M; School of Medicine, Guangxi University, 530004, Nanning, Guangxi Zhuang Autonomous Region, China.
Mou Z; School of Medicine, Guangxi University, 530004, Nanning, Guangxi Zhuang Autonomous Region, China.
Lin M; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China.
Yang L; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China.
Li Y; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China.
Yue Y; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China.
Pi H; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China.
Lu Y; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China.
He M; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China.
Zhang L; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China.
Chen C; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China. Electronic address: .
Zhou Z; Department of Environmental Medicine, School of Public Health, and Department of Emergency Medicine, First Affiliated Hospital, School of Medicine, Zhejiang University, 310058 Hangzhou, People's Republic of China. Electronic address: .
Yu Z; Department of Occupational Health, Army Medical University, 400038, Chongqing, People's Republic of China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Oct 15; Vol. 223, pp. 112554. Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Acetylcysteine*/metabolism
Acetylcysteine*/pharmacology
Arsenic*/metabolism
Arsenic*/toxicity
Animals ; Apoptosis ; Mice ; Mitochondria/metabolism ; Oxidative Stress ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
A review of alternative intravenous acetylcysteine regimens for acetaminophen overdose.
Autorzy :
Burnham K; Fisch College of Pharmacy, The University of Texas at Tyler, Tyler, TX, USA.
Yang T; Fisch College of Pharmacy, The University of Texas at Tyler, Tyler, TX, USA.
Smith H; Fisch College of Pharmacy, The University of Texas at Tyler, Tyler, TX, USA.
Knight S; Methodist Mansfield Medical Center, Mansfield, TX, USA.
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Źródło :
Expert review of clinical pharmacology [Expert Rev Clin Pharmacol] 2021 Oct; Vol. 14 (10), pp. 1267-1278. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Acetaminophen/*poisoning
Acetylcysteine/*administration & dosage
Antidotes/*administration & dosage
Acetylcysteine/adverse effects ; Administration, Intravenous ; Analgesics, Non-Narcotic/poisoning ; Antidotes/adverse effects ; Chemical and Drug Induced Liver Injury/etiology ; Chemical and Drug Induced Liver Injury/prevention & control ; Drug Overdose/drug therapy ; Humans
Czasopismo naukowe
Tytuł :
The Impact of N-Acetylcysteine on Autologous Fat Graft: First-in-Human Pilot Study.
Autorzy :
Pietruski P; Department of Plastic and Reconstructive Surgery, Medical Centre of Postgraduate Education, Prof. W. Orlowski Memorial Hospital, Warsaw, Poland.
Paskal W; Laboratory of Center for Preclinical Research, Department of Methodology, Medical University of Warsaw, Stefana Banacha 1B, 02-097, Warsaw, Mazowieckie, Poland.
Paluch Ł; Department of Radiology, Medical Centre of Postgraduate Education, Gruca Orthopaedic and Trauma Teaching Hospital, Otwock, Poland.
Paskal AM; Laboratory of Center for Preclinical Research, Department of Methodology, Medical University of Warsaw, Stefana Banacha 1B, 02-097, Warsaw, Mazowieckie, Poland.
Nitek Ż; Department of Radiology, Medical Centre of Postgraduate Education, Gruca Orthopaedic and Trauma Teaching Hospital, Otwock, Poland.
Włodarski P; Laboratory of Center for Preclinical Research, Department of Methodology, Medical University of Warsaw, Stefana Banacha 1B, 02-097, Warsaw, Mazowieckie, Poland. .
Walecki J; Department of Radiology, Medical Centre of Postgraduate Education, Gruca Orthopaedic and Trauma Teaching Hospital, Otwock, Poland.
Noszczyk B; Department of Plastic and Reconstructive Surgery, Medical Centre of Postgraduate Education, Prof. W. Orlowski Memorial Hospital, Warsaw, Poland.
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Źródło :
Aesthetic plastic surgery [Aesthetic Plast Surg] 2021 Oct; Vol. 45 (5), pp. 2397-2405. Date of Electronic Publication: 2020 Mar 27.
Typ publikacji :
Journal Article
MeSH Terms :
Acetylcysteine*/pharmacology
Mammaplasty*
Adipose Tissue ; Adult ; Female ; Humans ; Pilot Projects ; Retrospective Studies ; Transplantation, Autologous ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Acrolein but not its metabolite, 3-Hydroxypropylmercapturic acid (3HPMA), activates vascular transient receptor potential Ankyrin-1 (TRPA1): Physiological to toxicological implications.
Autorzy :
Jin L; Christina Lee Brown Envirome Institute, University of Louisville, Louisville, KY, USA; Diabetes and Obesity Center, University of Louisville, Louisville, KY, USA; American Heart Association-Tobacco Regulation and Addiction Center, University of Louisville, Louisville, KY, USA.
Lorkiewicz P; Christina Lee Brown Envirome Institute, University of Louisville, Louisville, KY, USA; Diabetes and Obesity Center, University of Louisville, Louisville, KY, USA; American Heart Association-Tobacco Regulation and Addiction Center, University of Louisville, Louisville, KY, USA.
Xie Z; Christina Lee Brown Envirome Institute, University of Louisville, Louisville, KY, USA; Diabetes and Obesity Center, University of Louisville, Louisville, KY, USA.
Bhatnagar A; Christina Lee Brown Envirome Institute, University of Louisville, Louisville, KY, USA; Diabetes and Obesity Center, University of Louisville, Louisville, KY, USA; American Heart Association-Tobacco Regulation and Addiction Center, University of Louisville, Louisville, KY, USA; Superfund Research Center, University of Louisville, Louisville, KY, USA.
Srivastava S; Christina Lee Brown Envirome Institute, University of Louisville, Louisville, KY, USA; Diabetes and Obesity Center, University of Louisville, Louisville, KY, USA; American Heart Association-Tobacco Regulation and Addiction Center, University of Louisville, Louisville, KY, USA; Superfund Research Center, University of Louisville, Louisville, KY, USA.
Conklin DJ; Christina Lee Brown Envirome Institute, University of Louisville, Louisville, KY, USA; Diabetes and Obesity Center, University of Louisville, Louisville, KY, USA; American Heart Association-Tobacco Regulation and Addiction Center, University of Louisville, Louisville, KY, USA; Superfund Research Center, University of Louisville, Louisville, KY, USA. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Sep 01; Vol. 426, pp. 115647. Date of Electronic Publication: 2021 Jul 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcysteine/*analogs & derivatives
Acrolein/*pharmacology
Aorta, Thoracic/*drug effects
Mesenteric Artery, Superior/*drug effects
TRPA1 Cation Channel/*physiology
Acetylcysteine/blood ; Acetylcysteine/pharmacology ; Acrolein/blood ; Animals ; Aorta, Thoracic/physiology ; Female ; GTPase-Activating Proteins/genetics ; GTPase-Activating Proteins/physiology ; Glutathione S-Transferase pi/genetics ; Glutathione S-Transferase pi/physiology ; Male ; Mesenteric Artery, Superior/physiology ; Mice, Inbred C57BL ; Mice, Knockout ; TRPA1 Cation Channel/genetics
Czasopismo naukowe
Tytuł :
Single Dose of N-Acetylcysteine in Local Anesthesia Increases Expression of HIF1α, MAPK1, TGFβ1 and Growth Factors in Rat Wound Healing.
Autorzy :
Paskal W; Department of Methodology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Kopka M; Department of Methodology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Stachura A; Department of Methodology, Medical University of Warsaw, 02-091 Warsaw, Poland.; Doctoral School, Medical University of Warsaw, 02-091 Warsaw, Poland.
Paskal AM; Department of Methodology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Pietruski P; Centre of Postgraduate Medical Education, Department of Replantation and Reconstructive Surgery, Gruca Teaching Hospital, 05-400 Otwock, Poland.
Pełka K; Department of Methodology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Woessner AE; Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Quinn KP; Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Galus R; Department of Histology and Embryology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Wejman J; Department of Pathology, Centre of Postgraduate Medical Education, 00-416 Warsaw, Poland.
Włodarski P; Department of Methodology, Medical University of Warsaw, 02-091 Warsaw, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 12; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 12.
Typ publikacji :
Journal Article
MeSH Terms :
Acetylcysteine/*administration & dosage
Hypoxia-Inducible Factor 1, alpha Subunit/*genetics
Mitogen-Activated Protein Kinase 1/*genetics
Transforming Growth Factor beta1/*genetics
Wound Healing/*drug effects
Acetylcysteine/pharmacology ; Anesthesia, Local ; Animals ; Antigens, CD/metabolism ; Antigens, Differentiation, Myelomonocytic/metabolism ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Oxidative Stress/drug effects ; Peroxidase/metabolism ; Platelet Endothelial Cell Adhesion Molecule-1/metabolism ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
N-acetyl cysteine abates hepatorenal toxicities induced by perfluorooctanoic acid exposure in male rats.
Autorzy :
Owumi S; CRMB Laboratory, Biochemistry Department, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, 200004, Nigeria. Electronic address: .
Bello T; CRMB Laboratory, Biochemistry Department, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, 200004, Nigeria.
Oyelere AK; School of Biochemistry and Chemistry, and Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, 30332-0400, USA.
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Źródło :
Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2021 Aug; Vol. 86, pp. 103667. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji :
Journal Article
MeSH Terms :
Acetylcysteine/*therapeutic use
Antioxidants/*therapeutic use
Caprylates/*toxicity
Fluorocarbons/*toxicity
Kidney/*drug effects
Liver/*drug effects
Acetylcysteine/pharmacology ; Alanine Transaminase/blood ; Alkaline Phosphatase/blood ; Animals ; Antioxidants/pharmacology ; Aspartate Aminotransferases/blood ; Creatinine/blood ; Kidney/metabolism ; Kidney/pathology ; Lipid Peroxidation/drug effects ; Liver/metabolism ; Liver/pathology ; Male ; Oxidative Stress/drug effects ; Oxidoreductases/metabolism ; Rats, Wistar ; Urea/blood ; gamma-Glutamyltransferase/blood
Czasopismo naukowe
Tytuł :
Invited Discussion on: The Impact of N-Acetylcysteine on Autologous Fat Graft-First-in-Human Pilot Study by Prof. Paweł Włodarski, Piotr Pietruski, MD, PhD; Wiktor Paskal, MD, PhD; Łukasz Paluch, MD, PhD; Adriana Maria Paskal, MD; Żaneta Nitek, MD, PhD; Jerzy Walecki, MD, PhD; Bartłomiej Noszczyk, MD, PhD.
Autorzy :
Kokai LE; University of Pittsburgh, 3380 Boulevard of the Allies, Suite 180, Pittsburgh, PA, 15213, USA.
Peter Rubin J; University of Pittsburgh, 3380 Boulevard of the Allies, Suite 180, Pittsburgh, PA, 15213, USA. .
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Źródło :
Aesthetic plastic surgery [Aesthetic Plast Surg] 2021 Oct; Vol. 45 (5), pp. 2406-2408. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Letter; Comment
MeSH Terms :
Acetylcysteine*
Education, Medical, Graduate*
Career Choice ; Humans ; Pilot Projects
Opinia redakcyjna
Tytuł :
Cardiac arrhythmia catheter ablation procedures guided by x-ray imaging: N-acetylcysteine protection against radiation-induced cellular damage (CARAPACE study): study design.
Autorzy :
Catto V; Heart Rhythm Center, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Stronati G; Cardiology and Arrhythmology Clinic, Marche Polytechnic University, University Hospital 'Ospedali Riuniti', Via Conca 71, Torrette (AN), 60126, Ancona, Italy. .
Porro B; Unit of Metabolomics and Cellular Biochemistry of Atherothrombosis, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Fiorelli S; Unit of Metabolomics and Cellular Biochemistry of Atherothrombosis, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Ricci V; Unit of Immunology and Functional Genomics, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Vavassori C; Unit of Immunology and Functional Genomics, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Russo E; Department of Cardiovascular Disease, Division of Cardiac Surgery, Casa Sollievo della Sofferenza IRCCS, San Giovanni Rotondo, Italy.
Guerra F; Cardiology and Arrhythmology Clinic, Marche Polytechnic University, University Hospital 'Ospedali Riuniti', Via Conca 71, Torrette (AN), 60126, Ancona, Italy.
Gasperetti A; Heart Rhythm Center, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Ribatti V; Heart Rhythm Center, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Sicuso R; Heart Rhythm Center, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Dello Russo A; Cardiology and Arrhythmology Clinic, Marche Polytechnic University, University Hospital 'Ospedali Riuniti', Via Conca 71, Torrette (AN), 60126, Ancona, Italy.
Veglia F; Unit of Biostatistics, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Tondo C; Heart Rhythm Center, Centro Cardiologico Monzino IRCCS, Milan, Italy.; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Cavalca V; Unit of Metabolomics and Cellular Biochemistry of Atherothrombosis, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Colombo GI; Unit of Immunology and Functional Genomics, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Tremoli E; Centro Cardiologico Monzino IRCCS, 20138, Milan, Italy.
Casella M; Heart Rhythm Center, Centro Cardiologico Monzino IRCCS, Milan, Italy.; Department of Clinical, Special and Dental Sciences, Marche Polytechnic University, University Hospital 'Ospedali Riuniti', Ancona, Italy.
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Źródło :
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing [J Interv Card Electrophysiol] 2021 Sep; Vol. 61 (3), pp. 577-582. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Acetylcysteine*
Catheter Ablation*
Adolescent ; Adult ; Arrhythmias, Cardiac ; Fluoroscopy ; Humans ; Prospective Studies ; X-Rays
Czasopismo naukowe
Tytuł :
S-Allylmercapto-N-acetylcysteine ameliorates elastase-induced chronic obstructive pulmonary disease in mice via regulating autophagy.
Autorzy :
Zheng D; Department of Pharmaceutics, Key Laboratory of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Cheelloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, PR China.
Wang J; College of Food Sciences and Pharmaceutical Engineering, Zaozhuang University, Zaozhuang, 277160, PR China.
Li G; Department of Pharmaceutics, Key Laboratory of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Cheelloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, PR China.
An L; Department of Pharmaceutics, Key Laboratory of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Cheelloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, PR China.
Qu Y; Department of Pharmaceutics, Key Laboratory of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Cheelloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, PR China.
Zhang Q; Department of Pharmaceutics, Key Laboratory of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Cheelloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, PR China.
Ye W; Department of Pharmaceutics, Key Laboratory of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Cheelloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, PR China.
Zhao X; Department of Pharmaceutics, Key Laboratory of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Cheelloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, PR China.
Zhao Z; Department of Pharmaceutics, Key Laboratory of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Cheelloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, PR China; Key University Laboratory of Pharmaceutics & Drug Delivery Systems of Shandong Province, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, Shandong, 250012, PR China; Pediatric Pharmaceutical Engineering Laboratory of Shandong Province, Shandong Dyne Marine Biopharmaceutical Company Limited, Rongcheng, Shandong, 264300, PR China; Chemical Immunopharmaceutical Engineering Laboratory of Shandong Province, Shandong Xili Pharmaceutical Company Limited, Heze, Shandong, 274300, PR China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Jul 12; Vol. 562, pp. 83-88. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autophagy*/drug effects
Acetylcysteine/*analogs & derivatives
Allyl Compounds/*therapeutic use
Pulmonary Disease, Chronic Obstructive/*chemically induced
Pulmonary Disease, Chronic Obstructive/*drug therapy
A549 Cells ; Acetylcysteine/pharmacology ; Acetylcysteine/therapeutic use ; Allyl Compounds/pharmacology ; Animals ; Disease Models, Animal ; Humans ; Inflammation/pathology ; Lung/drug effects ; Lung/pathology ; Mice ; Mice, Inbred BALB C ; Microtubule-Associated Proteins/metabolism ; Pancreatic Elastase ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Pulmonary Disease, Chronic Obstructive/pathology ; Swine ; TOR Serine-Threonine Kinases/metabolism ; Up-Regulation/drug effects ; Weight Loss/drug effects
Czasopismo naukowe
Tytuł :
N-acetyl cysteine co-treatment abates perfluorooctanoic acid-induced reproductive toxicity in male rats.
Autorzy :
Owumi SE; Change-Lab, CRMB Laboratory, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria.
Akomolafe AP; Change-Lab, CRMB Laboratory, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria.
Imosemi IO; Neuroanatomy Research Laboratories, Department of Anatomy, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria.
Odunola OA; Change-Lab, CRMB Laboratory, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria.
Oyelere AK; School of Biochemistry and Chemistry, Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, USA.
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Źródło :
Andrologia [Andrologia] 2021 Jun; Vol. 53 (5), pp. e14037. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji :
Journal Article
MeSH Terms :
Acetylcysteine*/pharmacology
Acetylcysteine*/therapeutic use
Fluorocarbons*/metabolism
Fluorocarbons*/toxicity
Animals ; Antioxidants/metabolism ; Antioxidants/pharmacology ; Caprylates ; Humans ; Male ; Oxidative Stress ; Rats ; Rats, Wistar ; Sperm Motility ; Spermatozoa/metabolism ; Testis/metabolism ; Testosterone/metabolism
Czasopismo naukowe
Tytuł :
The Use of Inhaled N-Acetylcysteine for Laryngopharyngeal Reflux Disease: A Randomized Controlled Trial.
Autorzy :
Jo YS; Department of Otorhinolaryngology-Head and Neck Surgery, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of Korea.
Choi IS; Department of Otorhinolaryngology-Head and Neck Surgery, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of Korea.
So YK; Department of Otorhinolaryngology-Head and Neck Surgery, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of Korea. Electronic address: .
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Źródło :
Journal of voice : official journal of the Voice Foundation [J Voice] 2021 Jul; Vol. 35 (4), pp. 618-624. Date of Electronic Publication: 2019 Dec 14.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Acetylcysteine*/adverse effects
Laryngopharyngeal Reflux*/diagnosis
Laryngopharyngeal Reflux*/drug therapy
Humans ; Prospective Studies ; Proton Pump Inhibitors/adverse effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
N-acetylcysteine is more effective than ellagic acid in preventing acrolein induced dysfunction in mitochondria isolated from rat liver.
Autorzy :
Shafie B; Department of Toxicology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Pourahmad J; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Rezaei M; Department of Toxicology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
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Źródło :
Journal of food biochemistry [J Food Biochem] 2021 Jul; Vol. 45 (7), pp. e13775. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcysteine*/pharmacology
Acrolein*/toxicity
Animals ; Cell Survival ; Ellagic Acid/pharmacology ; Liver ; Mitochondria ; Rats
Czasopismo naukowe
Tytuł :
Association of heat shock protein A2 expression and sperm quality after N-acetyl-cysteine supplementation in astheno-terato-zoospermic infertile men.
Autorzy :
Jannatifar R; Department of Reproductive Biology, Academic Center for Education Culture and Research (ACECR), Qom, Iran.
Cheraghi E; Department of Biology, Faculty of Sciences, University of Qom, Qom, Iran.
Nasr-Esfahani MH; Department of Reproductive Biotechnology, Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran.
Piroozmanesh H; Department of Reproductive Biology, Academic Center for Education Culture and Research (ACECR), Qom, Iran.
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Źródło :
Andrologia [Andrologia] 2021 Jun; Vol. 53 (5), pp. e14024. Date of Electronic Publication: 2021 Mar 04.
Typ publikacji :
Journal Article
MeSH Terms :
Acetylcysteine*/pharmacology
Acetylcysteine*/therapeutic use
Infertility, Male*/drug therapy
Dietary Supplements ; HSP70 Heat-Shock Proteins/genetics ; Heat-Shock Proteins ; Humans ; Male ; Spermatozoa
Czasopismo naukowe
Tytuł :
Systematic review and meta-analysis of the efficacy of N-acetylcysteine in the treatment of acute exacerbation of chronic obstructive pulmonary disease.
Autorzy :
Jiang C; Department of Respiratory and Critical Care Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China; Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, China.
Zou J; Department of Respiratory and Critical Care Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China; Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, China.
Lv Q; Department of Respiratory and Critical Care Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China; Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, China.
Yang Y; Department of Respiratory and Critical Care Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China; Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, China.
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Źródło :
Annals of palliative medicine [Ann Palliat Med] 2021 Jun; Vol. 10 (6), pp. 6564-6576.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Acetylcysteine*/therapeutic use
Pulmonary Disease, Chronic Obstructive*/drug therapy
Europe ; Forced Expiratory Volume ; Humans ; Respiratory Function Tests
Czasopismo naukowe
Tytuł :
A systematic review of N-acetylcysteine for treatment of acne vulgaris and acne-related associations and consequences: Focus on clinical studies.
Autorzy :
Mardani N; Department of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Mozafarpoor S; Department of Dermatology, Skin Disease and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Goodarzi A; Department of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Nikkhah F; Department of Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), Iran University of Medical Sciences, Tehran, Iran.
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Źródło :
Dermatologic therapy [Dermatol Ther] 2021 May; Vol. 34 (3), pp. e14915. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji :
Journal Article; Review; Systematic Review
MeSH Terms :
Acetylcysteine*
Acne Vulgaris*/diagnosis
Acne Vulgaris*/drug therapy
Anti-Bacterial Agents/therapeutic use ; Escherichia coli ; Humans ; Propionibacterium acnes ; Quality of Life
Czasopismo naukowe
Tytuł :
A Natural Alternative Treatment for Urinary Tract Infections: Itxasol©, the Importance of the Formulation.
Autorzy :
Cela-López JM; Achucarro Basque Center for Neuroscience, Campus of Biscay, University of the Basque Country/Euskal Herriko Unibertsitatea, Parque Científico de la UPV/EHU, Edificio Sede, Barrio Sarriena, 48940 Leioa, Spain.
Camacho Roldán CJ; Achucarro Basque Center for Neuroscience, Campus of Biscay, University of the Basque Country/Euskal Herriko Unibertsitatea, Parque Científico de la UPV/EHU, Edificio Sede, Barrio Sarriena, 48940 Leioa, Spain.
Gómez-Lizarraga G; Achucarro Basque Center for Neuroscience, Campus of Biscay, University of the Basque Country/Euskal Herriko Unibertsitatea, Parque Científico de la UPV/EHU, Edificio Sede, Barrio Sarriena, 48940 Leioa, Spain.
Martínez V; Achucarro Basque Center for Neuroscience, Campus of Biscay, University of the Basque Country/Euskal Herriko Unibertsitatea, Parque Científico de la UPV/EHU, Edificio Sede, Barrio Sarriena, 48940 Leioa, Spain.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 28; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Acetylcysteine/*therapeutic use
Arbutin/*therapeutic use
Biological Products/*therapeutic use
Umbelliferones/*therapeutic use
Urinary Tract Infections/*drug therapy
Acetylcysteine/chemistry ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/therapeutic use ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/therapeutic use ; Antifungal Agents/chemistry ; Antifungal Agents/therapeutic use ; Arbutin/chemistry ; Biofilms/drug effects ; Biofilms/growth & development ; Biological Products/chemistry ; Biomimetic Materials/chemistry ; Biomimetic Materials/therapeutic use ; Candida/drug effects ; Candida/growth & development ; Candida/pathogenicity ; Drug Combinations ; Female ; Gram-Negative Bacteria/drug effects ; Gram-Negative Bacteria/growth & development ; Gram-Negative Bacteria/pathogenicity ; Gram-Positive Bacteria/drug effects ; Gram-Positive Bacteria/growth & development ; Gram-Positive Bacteria/pathogenicity ; Humans ; Male ; Microbial Sensitivity Tests ; Umbelliferones/chemistry ; Urinary Tract Infections/microbiology ; Urinary Tract Infections/pathology
Czasopismo naukowe
Tytuł :
Acrylamide exposure and pulmonary function reduction in general population: The mediating effect of systemic inflammation.
Autorzy :
Wang B; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Wang X; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Yang S; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Cheng M; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhou Y; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhou M; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Ye Z; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Qiu W; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
He H; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Cen X; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhu C; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Cao L; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Mu G; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Ma J; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Wang D; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Xiao L; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Yuan J; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Chen W; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Electronic address: .
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Źródło :
The Science of the total environment [Sci Total Environ] 2021 Jul 15; Vol. 778, pp. 146304. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Acetylcysteine*
Acrylamide*/toxicity
Adult ; Biomarkers ; Cohort Studies ; Humans ; Inflammation/chemically induced
Czasopismo naukowe
Tytuł :
Supplementing glycine and N-acetylcysteine (GlyNAC) rapidly improves health-related quality of life and lowers perception of fatigue in patients with HIV.
Autorzy :
Sekhar RV; BCM-185, Translational Metabolism Unit, Division of Endocrinology, Diabetes and Metabolism, Baylor College of Medicine, One Baylor Plaza, Houston, TX, USA.
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Źródło :
AIDS (London, England) [AIDS] 2021 Jul 15; Vol. 35 (9), pp. 1522-1524.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcysteine*
HIV Infections*/complications
HIV Infections*/drug therapy
Fatigue ; Glycine ; Humans ; Perception ; Quality of Life
Czasopismo naukowe

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