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Tytuł:
Antiproliferative effects of mitochondria-targeted N-acetylcysteine and analogs in cancer cells.
Autorzy:
Cheng G; Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
Hardy M; CNRS, ICR, UMR 7273, Aix Marseille Univ, 13013, Marseille, France.
Kalyanaraman B; Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 May 04; Vol. 13 (1), pp. 7254. Date of Electronic Publication: 2023 May 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcysteine*/pharmacology
Pancreatic Neoplasms*/drug therapy
Humans ; Mice ; Animals ; Antioxidants/pharmacology ; Reactive Oxygen Species/pharmacology ; Mitochondria ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Two versus Three Infusion Regimens of N-Acetylcysteine for Acetaminophen Overdose.
Autorzy:
Tamur, Shadi (AUTHOR)
Alyahya, Bader (AUTHOR)
Alsani, Faisal (AUTHOR)
Bahauddin, Ammar Abdulraheem (AUTHOR)
Aljaid, Maryam (AUTHOR)
Al-Malki, Sultan (AUTHOR)
Alzahrani, Ahmad (AUTHOR)
Khayat, Abdullah (AUTHOR)
Shams, Anwar (AUTHOR)
Chalut, Dominic S. (AUTHOR)
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Źródło:
Pediatric Reports. Mar2024, Vol. 16 Issue 1, p232-242. 11p.
Czasopismo naukowe
Tytuł:
Chronic N-Acetyl-Cysteine Treatment Enhances the Expression of the Immediate Early Gene Nr4a1 in Response to an Acute Challenge in Male Rats: Comparison with the Antidepressant Venlafaxine.
Autorzy:
Brivio P; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, 20133 Milan, Italy.
Gallo MT; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, 20133 Milan, Italy.
Gruca P; Maj Institute of Pharmacology, Polish Academy of Sciences, 31-343 Krakow, Poland.
Lason M; Maj Institute of Pharmacology, Polish Academy of Sciences, 31-343 Krakow, Poland.
Litwa E; Maj Institute of Pharmacology, Polish Academy of Sciences, 31-343 Krakow, Poland.
Fumagalli F; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, 20133 Milan, Italy.
Papp M; Maj Institute of Pharmacology, Polish Academy of Sciences, 31-343 Krakow, Poland.
Calabrese F; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, 20133 Milan, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 15; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 15.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Acetylcysteine*/pharmacology
Acetylcysteine*/therapeutic use
Genes, Immediate-Early*
Animals ; Male ; Rats ; Antidepressive Agents/therapeutic use ; Rats, Wistar ; Venlafaxine Hydrochloride/pharmacology ; Venlafaxine Hydrochloride/therapeutic use
Czasopismo naukowe
Tytuł:
Effects of pulsed electromagnetic fields and N-acetylcysteine on transplantation of vitrified mouse ovarian tissue.
Autorzy:
Rasaeifar K; School of Biology, Damghan University, Damghan, Iran.
Zavareh S; School of Biology, Damghan University, Damghan, Iran.
Hajighasem-Kashani M; School of Biology, Damghan University, Damghan, Iran.
Nasiri M; School of Biology, Damghan University, Damghan, Iran.
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Źródło:
Electromagnetic biology and medicine [Electromagn Biol Med] 2023 Apr 03; Vol. 42 (2), pp. 67-80. Date of Electronic Publication: 2023 Aug 13.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcysteine*/pharmacology
Tumor Necrosis Factor-alpha*/genetics
Mice ; Female ; Animals ; Electromagnetic Fields ; Fibroblast Growth Factor 2 ; Interleukin-6 ; Vascular Endothelial Growth Factor A/genetics ; Antioxidants/pharmacology ; Antioxidants/metabolism
Czasopismo naukowe
Tytuł:
N-Acetylcysteine normalizes brain oxidative stress and neuroinflammation observed after protracted ethanol abstinence: a preclinical study in long-term ethanol-experienced male rats.
Autorzy:
Fernández-Rodríguez S; Department of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, Burjassot, 46100, Valencia, Spain.
Cano-Cebrián MJ; Department of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, Burjassot, 46100, Valencia, Spain.
Esposito-Zapero C; Department of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, Burjassot, 46100, Valencia, Spain.
Pérez S; Department of Physiology, Faculty of Pharmacy, University of Valencia, Burjassot, 46100, Valencia, Spain.
Guerri C; Department of Molecular and Cellular Pathology of Alcohol, Príncipe Felipe Research Center, Valencia, Spain.
Zornoza T; Department of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, Burjassot, 46100, Valencia, Spain.
Polache A; Department of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, Burjassot, 46100, Valencia, Spain. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2023 Apr; Vol. 240 (4), pp. 725-738. Date of Electronic Publication: 2023 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Ethanol*
Acetylcysteine*/pharmacology
Rats ; Male ; Animals ; Rats, Wistar ; Alcohol Abstinence ; Neuroinflammatory Diseases ; Brain ; Chronic Disease ; Oxidative Stress ; Glutamates/metabolism ; Alcohol Drinking/drug therapy
Czasopismo naukowe
Tytuł:
Effect of N -acetyl-l-cysteine on Cell Phenotype and Autophagy in Pichia pastoris Expressing Human Serum Albumin and Porcine Follicle-Stimulating Hormone Fusion Protein.
Autorzy:
Xu Y; School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212100, China.
Geng Z; School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212100, China.
Yang C; School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212100, China.
Zhou H; School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212100, China.
Wang Y; School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212100, China.
Kuerban B; School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212100, China.
Luo G; School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212100, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Mar 29; Vol. 28 (7). Date of Electronic Publication: 2023 Mar 29.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcysteine*/pharmacology
Acetylcysteine*/metabolism
Serum Albumin, Human*/metabolism
Animals ; Swine ; Humans ; Pichia/genetics ; Pichia/metabolism ; Recombinant Proteins/metabolism ; Autophagy ; Follicle Stimulating Hormone/metabolism ; Phenotype ; Recombinant Fusion Proteins/genetics
SCR Organism:
Komagataella pastoris
Czasopismo naukowe
Tytuł:
Effects of N-acetylcysteine on systemic lupus erythematosus disease activity and its associated complications: a randomized double-blind clinical trial study.
Autorzy:
Abbasifard M; Non-Communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.; Department of Internal Medicine, Ali-Ibn Abi-Talib Hospital, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Khorramdelazad H; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Rostamian A; Rheumatology Research Center, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Rezaian M; Biostatistics Group, Division of Epidemiology & Health Sciences, The University of Manchester, Manchester, UK.
Askari PS; Non-Communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Sharifi GTK; Department of Surgery, Ali-Ibn-Abi-Talib Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Parizi MK; Non-Communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Sharifi MTK; School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Najafizadeh SR; Rheumatology Research Center, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran. .
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Źródło:
Trials [Trials] 2023 Feb 21; Vol. 24 (1), pp. 129. Date of Electronic Publication: 2023 Feb 21.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Acetylcysteine*/therapeutic use
Lupus Erythematosus, Systemic*/drug therapy
Humans ; Severity of Illness Index ; Kidney ; Double-Blind Method ; Treatment Outcome
Czasopismo naukowe
Tytuł:
N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-α Signaling.
Autorzy:
Sakai M; Department of Psychiatric Nursing, Graduate School of Medicine, Tohoku University, Sendai 980-8575, Japan.
Yu Z; Department of Psychiatry, Graduate School of Medicine, Tohoku University, Sendai 980-8575, Japan.
Taniguchi M; Division of Pharmacology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Picotin R; Medical Faculty, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Oyama N; Department of Psychiatric Nursing, Graduate School of Medicine, Tohoku University, Sendai 980-8575, Japan.
Stellwagen D; Department of Neurology and Neurosurgery, The Research Institute of the McGill University Health Center, Montreal, QC H3G 1A4, Canada.
Ono C; Department of Psychiatry, Graduate School of Medicine, Tohoku University, Sendai 980-8575, Japan.
Kikuchi Y; Department of Psychiatry, Graduate School of Medicine, Tohoku University, Sendai 980-8575, Japan.
Matsui K; Super-network Brain Physiology, Graduate School of Life Sciences, Tohoku University, Sendai 980-8577, Japan.
Nakanishi M; Department of Psychiatric Nursing, Graduate School of Medicine, Tohoku University, Sendai 980-8575, Japan.
Yoshii H; Department of Psychiatric Nursing, Graduate School of Medicine, Tohoku University, Sendai 980-8575, Japan.
Furuyashiki T; Division of Pharmacology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Abe T; Department of Biomedical Engineering Regenerative and Biomedical Engineering Medical Science, Graduate School of Biomedical Engineering, Tohoku University, Sendai 980-8575, Japan.
Tomita H; Department of Psychiatry, Graduate School of Medicine, Tohoku University, Sendai 980-8575, Japan.; Department of Disaster Psychiatry, International Research Institute for Disaster Science, Tohoku University, Sendai 980-8573, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 14; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcysteine*/pharmacology
Inflammation*/metabolism
Inflammation*/pathology
Microglia*/drug effects
Microglia*/metabolism
Microglia*/pathology
Tumor Necrosis Factor-alpha*/metabolism
Animals ; Humans ; Mice ; Lipopolysaccharides/pharmacology ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Cumulative Effects of Paraoxon and Leptin on Oxidative Damages in Rat Tissues: Prophylactic and Therapeutic Roles of N-Acetylcysteine.
Autorzy:
Khazaie S; Department of Biochemistry, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Jafari M; Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran. .
Golamloo M; Department of Biochemistry, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Asgari A; Exercise Physiology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Heydari J; Department of Biochemistry, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Salehi M; Neurosciences Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Salem F; Department of Biochemistry, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
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Źródło:
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2023 Feb; Vol. 88 (2), pp. 165-178.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/pharmacology
Antioxidants*/metabolism
Acetylcysteine*/pharmacology
Rats ; Male ; Animals ; Paraoxon/toxicity ; Rats, Wistar ; Leptin/pharmacology ; Oxidative Stress
Czasopismo naukowe
Tytuł:
N-acetylcysteine for schizophrenia: A systematic review and meta-analysis.
Autorzy:
Kishi T; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan.
Sakuma K; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan.
Hatano M; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan.; Department of Clinical Pharmacy, Fujita Health University School of Medicine, Toyoake, Japan.
Iwata N; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan.
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Źródło:
Psychiatry and clinical neurosciences [Psychiatry Clin Neurosci] 2023 Feb; Vol. 77 (2), pp. 119-121. Date of Electronic Publication: 2022 Nov 19.
Typ publikacji:
Meta-Analysis; Systematic Review; Letter
MeSH Terms:
Acetylcysteine*/pharmacology
Acetylcysteine*/therapeutic use
Schizophrenia*/drug therapy
Humans
Raport
Tytuł:
Intranasal Administration of GRP78 Protein (HSPA5) Confers Neuroprotection in a Lactacystin-Induced Rat Model of Parkinson's Disease.
Autorzy:
Pazi MB; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, 44 Thorez pr., St. Petersburg 194223, Russia.
Belan DV; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, 44 Thorez pr., St. Petersburg 194223, Russia.
Komarova EY; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky pr., St. Petersburg 194064, Russia.
Ekimova IV; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, 44 Thorez pr., St. Petersburg 194223, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 02; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Parkinson Disease*/drug therapy
Parkinson Disease*/etiology
Synucleinopathies*
Acetylcysteine/*analogs & derivatives
Humans ; Animals ; Rats ; alpha-Synuclein/genetics ; Endoplasmic Reticulum Chaperone BiP ; Administration, Intranasal ; Neuroprotection
Czasopismo naukowe
Tytuł:
Eight weeks of treatment with mineralocorticoid receptor blockade does not alter vascular function in individuals with and without type 2 diabetes.
Autorzy:
Finsen SH; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Nephrology, Odense University Hospital, Odense, Denmark.
Hansen MR; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Hansen PBL; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Mortensen SP; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
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Źródło:
Physiological reports [Physiol Rep] 2024 Apr; Vol. 12 (7), pp. e16010.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/drug therapy
Receptors, Mineralocorticoid*
Humans ; Acetylcholine/administration & dosage ; Acetylcholine/pharmacology ; Acetylcholine/therapeutic use ; Acetylcysteine ; Aldosterone
Czasopismo naukowe
Tytuł:
Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response.
Autorzy:
Smabers LP; Department of Medical Oncology, University Medical Center Utrecht (UMCU), Utrecht, The Netherlands.
Wensink E; Department of Medical Oncology, University Medical Center Utrecht (UMCU), Utrecht, The Netherlands.
Verissimo CS; HUB Organoids B.V, Utrecht, The Netherlands.
Koedoot E; HUB Organoids B.V, Utrecht, The Netherlands.
Pitsa KC; HUB Organoids B.V, Utrecht, The Netherlands.
Huismans MA; Molecular Cancer Research, Center for Molecular Medicine, UMCU, Utrecht, The Netherlands.
Higuera Barón C; HUB Organoids B.V, Utrecht, The Netherlands.
Doorn M; HUB Organoids B.V, Utrecht, The Netherlands.
Valkenburg-van Iersel LB; Department of Medical Oncology, Maastricht University Medical Center, Maastricht, The Netherlands.
Cirkel GA; Department of Medical Oncology, Meander Medical Center, Amersfoort, The Netherlands.
Brousali A; Utrecht Platform for Organoid Technology (UPORT), UMCU, Utrecht, The Netherlands.
Overmeer R; HUB Organoids B.V, Utrecht, The Netherlands.
Koopman M; Department of Medical Oncology, University Medical Center Utrecht (UMCU), Utrecht, The Netherlands.
Braat MN; Department of Radiology, UMCU, Utrecht, The Netherlands.
Penning de Vries B; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, UMCU, Utrecht, The Netherlands.
Elias SG; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, UMCU, Utrecht, The Netherlands.
Vries RG; HUB Organoids B.V, Utrecht, The Netherlands.
Kranenburg O; Utrecht Platform for Organoid Technology (UPORT), UMCU, Utrecht, The Netherlands.; Laboratory of Translational Oncology, Division of Imaging and Cancer, UMCU, Utrecht, The Netherlands.
Boj SF; HUB Organoids B.V, Utrecht, The Netherlands. .
Roodhart JM; Department of Medical Oncology, University Medical Center Utrecht (UMCU), Utrecht, The Netherlands. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Feb 27; Vol. 43 (1), pp. 61. Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Colonic Neoplasms*/drug therapy
Humans ; Irinotecan/pharmacology ; Irinotecan/therapeutic use ; Oxaliplatin/pharmacology ; Oxaliplatin/therapeutic use ; Acetylcysteine/therapeutic use ; Precision Medicine ; Fluorouracil/pharmacology ; Fluorouracil/therapeutic use ; Organoids ; Antineoplastic Combined Chemotherapy Protocols/adverse effects
Czasopismo naukowe
Tytuł:
Efficacy of unithiol (2,3-dimercaptopropanesulfonate) and acetylcysteine in a patient with arthroplastic cobalt toxicity.
Autorzy:
Pelclova D; Toxicological Information Centre, Department of Occupational Medicine, Charles University, and General University Hospital in Prague, Czech Republic.
Lach K; Public Health Institute, Ostrava, Czech Republic.
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Źródło:
Clinical toxicology (Philadelphia, Pa.) [Clin Toxicol (Phila)] 2023 Mar; Vol. 61 (3), pp. 201-202. Date of Electronic Publication: 2023 Feb 23.
Typ publikacji:
Letter
MeSH Terms:
Unithiol*
Acetylcysteine*/therapeutic use
Humans ; Antidotes/therapeutic use ; Cobalt
Opinia redakcyjna
Tytuł:
The therapeutic effect of N-acetylcysteine as an add-on to methadone maintenance therapy medication in outpatients with substance use disorders: A randomized, double-blind, placebo-controlled clinical trial.
Autorzy:
Padoei F; Student Research Committee, Kashan University of Medical Sciences, Kashan, Iran.
Mamsharifi P; Department of Psychology, Allameh Tabataba'i University, Tehran, Iran.
Hazegh P; Department of Psychiatry, Kashan University of Medical Sciences, Kashan, Iran.
Boroumand H; Student Research Committee, Kashan University of Medical Sciences, Kashan, Iran.
Ostadmohammady F; Drug abuse treatment center, Kashan University of Medical Sciences, Kashan, Iran.
Abbaszadeh-Mashkani S; Student Research Committee, Kashan University of Medical Sciences, Kashan, Iran.
Banafshe HR; Physiology Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Matini AH; Department of Clinical Pathology, Kashan University of Medical Sciences, Kashan, Iran.
Ghaderi A; Department of Addiction studies, School of Medical, Kashan University of Medical Sciences, Kashan, Iran.; Clinical Research Development Unit-Matini/Kargarnejad Hospital, Kashan University of Medical Sciences, Kashan, Iran.
Dehkohneh SG; Department of Pharmacy, Acharya BM ready college of Pharmacy, Rajiv Gandhi University of Health Sciences, Bangalore, Karnataka, India.
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Źródło:
Brain and behavior [Brain Behav] 2023 Jan; Vol. 13 (1), pp. e2823. Date of Electronic Publication: 2022 Nov 30.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcysteine*/pharmacology
Acetylcysteine*/therapeutic use
Substance-Related Disorders*
Humans ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Outpatients ; Antioxidants ; Methadone/therapeutic use ; Double-Blind Method
Czasopismo naukowe
Tytuł:
Akt Signaling and Nitric Oxide Synthase as Possible Mediators of the Protective Effect of N-acetyl-L-cysteine in Prediabetes Induced by Sucrose.
Autorzy:
Castro MC; CENEXA-Centro de Endocrinología Experimental y Aplicada (UNLP-CONICET CCT La Plata, FCM, CEAS CICPBA), Calle 60 y 120, La Plata 1900, Argentina.
Villagarcía HG; CENEXA-Centro de Endocrinología Experimental y Aplicada (UNLP-CONICET CCT La Plata, FCM, CEAS CICPBA), Calle 60 y 120, La Plata 1900, Argentina.
Di Sarli Gutiérrez L; CENEXA-Centro de Endocrinología Experimental y Aplicada (UNLP-CONICET CCT La Plata, FCM, CEAS CICPBA), Calle 60 y 120, La Plata 1900, Argentina.
Arbeláez LG; CIC-Centro de Investigaciones Cardiovasculares (UNLP-CONICET CCT La Plata, FCM), Calle 60 y 120, La Plata 1900, Argentina.
Schinella G; Facultad de Ciencias Médicas, UNLP, Calle 60 y 120, La Plata 1900, Argentina.; Instituto de Ciencias de la Salud, UNAJ-CICPBA (Av. Calchaquí 6200), Florencia Varela 1888, Argentina.
Massa ML; CENEXA-Centro de Endocrinología Experimental y Aplicada (UNLP-CONICET CCT La Plata, FCM, CEAS CICPBA), Calle 60 y 120, La Plata 1900, Argentina.
Francini F; CENEXA-Centro de Endocrinología Experimental y Aplicada (UNLP-CONICET CCT La Plata, FCM, CEAS CICPBA), Calle 60 y 120, La Plata 1900, Argentina.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 19; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Prediabetic State*/drug therapy
Diabetes Mellitus, Type 2*/metabolism
Insulin Resistance*
Rats ; Male ; Animals ; Acetylcysteine/pharmacology ; Acetylcysteine/metabolism ; Rats, Wistar ; Proto-Oncogene Proteins c-akt/metabolism ; Sucrose/pharmacology ; Oxidative Stress ; Insulin/metabolism ; Signal Transduction ; Glucose/pharmacology ; Nitric Oxide/metabolism
Czasopismo naukowe
Tytuł:
N-acetylcysteine regulates dental follicle stem cell osteogenesis and alveolar bone repair via ROS scavenging.
Autorzy:
Meng Z; Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Tianjin Medical University, Tianjin, China.
Liu J; Department of Prosthodontics, School and Hospital of Stomatology, Tianjin Medical University, 12 Qixiangtai Road, Tianjin, 300070, China.
Feng Z; Department of Prosthodontics, School and Hospital of Stomatology, Tianjin Medical University, 12 Qixiangtai Road, Tianjin, 300070, China.
Guo S; Department of Prosthodontics, School and Hospital of Stomatology, Tianjin Medical University, 12 Qixiangtai Road, Tianjin, 300070, China.
Wang M; School of Stomatology, Tianjin Medical University, Tianjin, China.
Wang Z; Department of Prosthodontics, School and Hospital of Stomatology, Tianjin Medical University, 12 Qixiangtai Road, Tianjin, 300070, China.
Li Z; Department of Prosthodontics, School and Hospital of Stomatology, Tianjin Medical University, 12 Qixiangtai Road, Tianjin, 300070, China.
Li H; School of Stomatology, Tianjin Medical University, Tianjin, China. .
Sui L; Department of Prosthodontics, School and Hospital of Stomatology, Tianjin Medical University, 12 Qixiangtai Road, Tianjin, 300070, China. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2022 Sep 08; Vol. 13 (1), pp. 466. Date of Electronic Publication: 2022 Sep 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcysteine*/metabolism
Acetylcysteine*/pharmacology
Osteogenesis*/genetics
Animals ; Antioxidants/metabolism ; Antioxidants/pharmacology ; Cell Differentiation/physiology ; Cells, Cultured ; Dental Sac/metabolism ; Humans ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; RNA/metabolism ; Rats ; Reactive Oxygen Species/metabolism ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł:
Is the combination of linagliptin and allopurinol better prophylaxis against post-contrast acute kidney injury? A multicenter prospective randomized controlled study.
Autorzy:
Fayed A; Nephrology Unit, Internal Medicine Department, Kasr Alainy School of Medicine, Cairo University, Giza, Egypt.
Hammad AA; Endocrinology Unit, Internal Medicine Department, Faculty of Medicine, Fayoum University, Faiyum, Egypt.
Abdulazim DO; Rheumatology and Rehabilitation Department, Kasr Alainy School of Medicine, Cairo University, Giza, Egypt.
Hammad H; Nephrology Unit, Internal Medicine Department, Kasr Alainy School of Medicine, Cairo University, Giza, Egypt.
Amin M; Critical Care Medicine Department, Internal Medicine Department, Kasr Alainy School of Medicine, Cairo University, Giza, Egypt.
Elhadidy S; Critical Care Medicine Department, Internal Medicine Department, Kasr Alainy School of Medicine, Cairo University, Giza, Egypt.
Salem MM; Endocrinology Unit, Internal Medicine Department, Kasr Alainy School of Medicine, Cairo University, Giza, Egypt.
ElAzim IMA; Critical Care Medicine, Theodor Bilharz Research Institute, Cairo, Egypt.
Zsom L; Fresenius Medical Care Hungary, Cegléd, Hungary.
Csongradi E; Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Soliman KM; Department of Surgery, Division of Transplant, Medical University of South Carolina, Charleston, SC, USA.
Sharaf El Din UA; Nephrology Unit, Internal Medicine Department, Kasr Alainy School of Medicine, Cairo University, Giza, Egypt.
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Źródło:
Renal failure [Ren Fail] 2023 Dec; Vol. 45 (1), pp. 2194434.
Typ publikacji:
Randomized Controlled Trial; Multicenter Study; Journal Article
MeSH Terms:
Acute Kidney Injury*/chemically induced
Acute Kidney Injury*/etiology
Acute Kidney Injury*/prevention & control
Allopurinol*/administration & dosage
Allopurinol*/therapeutic use
Diabetic Nephropathies*/classification
Diabetic Nephropathies*/complications
Diabetic Nephropathies*/diagnosis
Linagliptin*/administration & dosage
Linagliptin*/therapeutic use
Contrast Media*/adverse effects
Protective Agents*/administration & dosage
Protective Agents*/adverse effects
Protective Agents*/therapeutic use
Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/diagnosis ; Prospective Studies ; Renal Insufficiency, Chronic/classification ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/diagnosis ; Chemoprevention/methods ; Drug Therapy, Combination ; Acetylcysteine/administration & dosage ; Acetylcysteine/therapeutic use ; Saline Solution/administration & dosage ; Saline Solution/therapeutic use
Czasopismo naukowe
Tytuł:
Interaction of Thiol Antioxidants with α,β-Unsaturated Ketone Moiety: Its Implication for Stability and Bioactivity of Curcuminoids.
Autorzy:
Lee BH; Department of Physiology, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.; Department of Food Science and Technology, College of Natural Science, Seoul Women's University, 621, Hwarangro, Nowon-gu, Seoul 01797, Republic of Korea.
Song E; Department of Food Science and Technology, College of Natural Science, Seoul Women's University, 621, Hwarangro, Nowon-gu, Seoul 01797, Republic of Korea.
Hong J; Department of Food Science and Technology, College of Natural Science, Seoul Women's University, 621, Hwarangro, Nowon-gu, Seoul 01797, Republic of Korea.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Nov 22; Vol. 28 (23). Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/pharmacology
Curcumin*/pharmacology
Diarylheptanoids ; Sulfhydryl Compounds/pharmacology ; Glutathione/pharmacology ; Acetylcysteine/pharmacology
Czasopismo naukowe
Tytuł:
Acetylcysteine increases sensitivity of ceftazidime-avibactam-resistant enterobacterales with different enzymatic resistance to ceftazidime-avibactam in vitro and in vivo.
Autorzy:
Huang Z; Department of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Han Y; Department of Medical Lab Science, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Zhang X; Department of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Sun Y; Department of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Lin Y; Department of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Feng L; Department of Medical Lab Science, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Zhou T; Department of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China. .
Wang Z; Department of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China. .
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Źródło:
BMC microbiology [BMC Microbiol] 2023 Nov 03; Vol. 23 (1), pp. 321. Date of Electronic Publication: 2023 Nov 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Bacterial Agents*/pharmacology
Anti-Bacterial Agents*/therapeutic use
Gammaproteobacteria*/metabolism
Animals ; Mice ; Acetylcysteine/pharmacology ; Ceftazidime/pharmacology ; Azabicyclo Compounds/pharmacology ; Drug Combinations ; Microbial Sensitivity Tests ; beta-Lactamases/metabolism
Czasopismo naukowe

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