Temat: "ADAM Proteins" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Recombinant ADAMTS-13 Improves Survival of Mice Subjected to Endotoxemia.
Autorzy:: Gao D; Bloodworks Research Institute, Seattle, WA 98102, USA.; Department of Chemistry, Pomona College, Claremont, CA 91711, USA.
Zhou Z; Bloodworks Research Institute, Seattle, WA 98102, USA.
Ma R; Cardiovascular Sciences, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Wu H; Cardiovascular Sciences, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Nguyen T; Division of Critical Care Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.; Center for Translational Research on Inflammatory Diseases at the Michael E. DeBakey Veteran Administration Medical Center, Houston, TX 77030, USA.
Liu L; Tianjin Neurology Research Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.
Dong J; Bloodworks Research Institute, Seattle, WA 98102, USA.; Division of Hematology, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 22; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 22.
Typ publikacji:: Journal Article
MeSH Terms:: ADAM Proteins*
Endotoxemia*/drug therapy
Animals ; Mice ; Endothelial Cells ; ADAMTS13 Protein ; Lipopolysaccharides ; Mice, Inbred C57BL ; von Willebrand Factor

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: Digital spatial profiling of segmental outflow regions in trabecular meshwork reveals a role for ADAM15.
Autorzy:: Faralli JA; Departments of Pathology & Laboratory Medicine, University of Wisconsin, Madison, Wisconsin, United States of America.
Filla MS; Departments of Pathology & Laboratory Medicine, University of Wisconsin, Madison, Wisconsin, United States of America.
Yang YF; Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
Sun YY; Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
Johns K; Departments of Pathology & Laboratory Medicine, University of Wisconsin, Madison, Wisconsin, United States of America.
Keller KE; Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
Peters DM; Departments of Pathology & Laboratory Medicine, University of Wisconsin, Madison, Wisconsin, United States of America.; Ophthalmology & Visual Sciences, University of Wisconsin, Madison, Wisconsin, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Feb 23; Vol. 19 (2), pp. e0298802. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Trabecular Meshwork*/metabolism
Aqueous Humor*/metabolism
Humans ; Sclera ; Proteoglycans/metabolism ; Integrins/genetics ; Integrins/metabolism ; Intraocular Pressure ; Membrane Proteins/metabolism ; ADAM Proteins/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: ADAM33's Role in Asthma Pathogenesis: An Overview.
Autorzy:: Sleziak J; Student Research Group of Internal Medicine and Allergology, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Gawor A; Student Research Group of Internal Medicine and Allergology, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Błażejewska M; Student Research Group of Internal Medicine and Allergology, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Antosz K; Student Research Group of Internal Medicine and Allergology, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Gomułka K; Department of Internal Medicine, Pneumology and Allergology, Wroclaw Medical University, 50-367 Wroclaw, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 15; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Asthma*/genetics
Asthma*/drug therapy
Bronchial Hyperreactivity*
Humans ; Airway Remodeling ; Genetic Predisposition to Disease ; ADAM Proteins/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: Circ_0005714/miR-223-3p/ADAM9 regulatory axis affects proliferation, migration, invasion, and angiopoiesis in trophoblast cells.
Autorzy:: Hu X; Department of Obstetrics and Gynecology, Lishui People's Hospital, Lishui City, PR China.
Xia W; Department of Obstetrics and Gynecology, Lishui People's Hospital, Lishui City, PR China.; Pokaż więcej
Źródło:: Autoimmunity [Autoimmunity] 2022 Dec; Vol. 55 (8), pp. 640-649. Date of Electronic Publication: 2022 Jul 26.
Typ publikacji:: Journal Article
MeSH Terms:: ADAM Proteins*/genetics
ADAM Proteins*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
RNA, Circular*/genetics
Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Disintegrins/genetics ; Disintegrins/metabolism ; Female ; Humans ; Membrane Proteins/genetics ; Pregnancy ; Trophoblasts/metabolism ; beta Catenin/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: Novel ADAMTS13 mutations in a patient with congenital thrombotic thrombocytopenic purpura.
Autorzy:: Wang Z; Department of Hematology, The Second Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Zhang X; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Lu X; Department of Hematology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.; Department of Hematology, Wannan Medical College, Wuhu, People's Republic of China.
Peng P; Department of Hematology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.; Department of Hematology, Wannan Medical College, Wuhu, People's Republic of China.
Wang H; Department of Hematology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.
Feng S; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Zhou L; Department of Hematology, The Second Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.; Pokaż więcej
Źródło:: Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2269513. Date of Electronic Publication: 2023 Oct 18.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: Purpura, Thrombotic Thrombocytopenic*
Humans ; Male ; ADAM Proteins/genetics ; ADAM Proteins/metabolism ; ADAMTS13 Protein/genetics ; Codon, Nonsense ; Mutation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: Ectodomain shedding of EGFR ligands serves as an activation readout for TRP channels.
Autorzy:: Tatsumi M; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Kishi T; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Ishida S; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Kawana H; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Uwamizu A; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Ono Y; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Kawakami K; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Aoki J; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Inoue A; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Jan 20; Vol. 18 (1), pp. e0280448. Date of Electronic Publication: 2023 Jan 20 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: ADAM Proteins*/metabolism
Transforming Growth Factor alpha*/metabolism
Amyloid Precursor Protein Secretases ; ADAM17 Protein ; Epidermal Growth Factor/metabolism ; ADAM10 Protein/metabolism ; ErbB Receptors/metabolism ; Ligands

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: A Bioengineering Strategy to Control ADAM10 Activity in Living Cells.
Autorzy:: Pastore F; Department of Neuroscience, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Battistoni M; Department of Neuroscience, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Sollazzo R; Department of Neuroscience, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Renna P; Department of Neuroscience, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.; Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Paciello F; Department of Neuroscience, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.; Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Li Puma DD; Department of Neuroscience, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.; Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Barone E; Department of Biochemical Sciences 'A. Rossi-Fanelli', Sapienza University of Rome, 00185 Rome, Italy.
Dagliyan O; Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, 171 65 Stockholm, Sweden.
Ripoli C; Department of Neuroscience, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.; Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Grassi C; Department of Neuroscience, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.; Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 04; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 04.
Typ publikacji:: Journal Article
MeSH Terms:: ADAM Proteins*/metabolism
Alzheimer Disease*/genetics
Alzheimer Disease*/therapy
Alzheimer Disease*/metabolism
Animals ; Humans ; ADAM10 Protein/genetics ; ADAM10 Protein/metabolism ; Membrane Proteins/metabolism ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; Amyloid Precursor Protein Secretases/metabolism ; Bioengineering ; Mammals/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: Tetraspanin 8 Subfamily Members Regulate Substrate-Specificity of a Disintegrin and Metalloprotease 17.
Autorzy:: Müller M; Institute of Biochemistry, Medical Faculty, Christian-Albrechts-University Kiel, 24118 Kiel, Germany.
Saunders C; Institute of Biochemistry, Medical Faculty, Christian-Albrechts-University Kiel, 24118 Kiel, Germany.
Senftleben A; Institute of Biochemistry, Medical Faculty, Christian-Albrechts-University Kiel, 24118 Kiel, Germany.
Heidbuechel JPW; Institute of Biochemistry, Medical Faculty, Christian-Albrechts-University Kiel, 24118 Kiel, Germany.
Halwachs B; Tumour Immunology Laboratory, Department of Biosciences and Medical Biology, Paris-Lodron-University Salzburg, 5020 Salzburg, Austria.
Bolik J; Institute of Biochemistry, Medical Faculty, Christian-Albrechts-University Kiel, 24118 Kiel, Germany.
Hedemann N; Department of Gynaecology, University Medical Center Schleswig-Holstein, 24105 Kiel, Germany.
Röder C; Institute of Experimental Cancer Research, Medical Faculty, University Medical Center Schleswig-Holstein, 24105 Kiel, Germany.
Bauerschlag D; Department of Gynaecology, University Medical Center Schleswig-Holstein, 24105 Kiel, Germany.
Rose-John S; Institute of Biochemistry, Medical Faculty, Christian-Albrechts-University Kiel, 24118 Kiel, Germany.
Schmidt-Arras D; Institute of Biochemistry, Medical Faculty, Christian-Albrechts-University Kiel, 24118 Kiel, Germany.; Tumour Immunology Laboratory, Department of Biosciences and Medical Biology, Paris-Lodron-University Salzburg, 5020 Salzburg, Austria.; Pokaż więcej
Źródło:: Cells [Cells] 2022 Aug 29; Vol. 11 (17). Date of Electronic Publication: 2022 Aug 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: ADAM Proteins*/genetics
ADAM Proteins*/metabolism
Disintegrins*
Membrane Proteins ; Substrate Specificity ; Tetraspanins/genetics ; Tumor Necrosis Factor-alpha/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: Inherited ADAMTS13 mutations associated with Thrombotic Thrombocytopenic Purpura: a short review and update.
Autorzy:: Markham-Lee Z; School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK and.; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Morgan NV; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Emsley J; School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK and.; Pokaż więcej
Źródło:: Platelets [Platelets] 2023 Dec; Vol. 34 (1), pp. 2138306. Date of Electronic Publication: 2022 Oct 25.
Typ publikacji:: Journal Article
MeSH Terms:: Purpura, Thrombotic Thrombocytopenic*/genetics
Humans ; von Willebrand Factor/genetics ; von Willebrand Factor/metabolism ; ADAM Proteins/metabolism ; ADAMTS13 Protein/genetics ; Mutation ; Germ-Line Mutation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 10.

Tytuł:: The Autism Spectrum Disorder-Associated Bacterial Metabolite p -Cresol Derails the Neuroimmune Response of Microglial Cells Partially via Reduction of ADAM17 and ADAM10.
Autorzy:: Zheng Y; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, 3584 CG Utrecht, The Netherlands.
Prince NZ; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, 3584 CG Utrecht, The Netherlands.
Peralta Marzal LN; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, 3584 CG Utrecht, The Netherlands.
Ahmed S; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, 3584 CG Utrecht, The Netherlands.
Garssen J; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, 3584 CG Utrecht, The Netherlands.; Global Centre of Excellence Immunology, Danone-Nutricia Research, 3584 CT Utrecht, The Netherlands.
Perez Pardo P; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, 3584 CG Utrecht, The Netherlands.
Kraneveld AD; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, 3584 CG Utrecht, The Netherlands.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Sep 20; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 20.
Typ publikacji:: Journal Article
MeSH Terms:: ADAM Proteins*/metabolism
Autism Spectrum Disorder*/etiology
ADAM17 Protein/*metabolism
ADAM10 Protein/metabolism ; Amyloid Precursor Protein Secretases/metabolism ; Animals ; Cresols ; Disintegrins ; Glucuronides ; Interleukin-6/metabolism ; Lipopolysaccharides/toxicity ; Male ; Membrane Proteins ; Mice ; Microglia/metabolism ; Sulfates ; Sulfuric Acid Esters ; Transforming Growth Factor beta1 ; Tumor Necrosis Factor-alpha/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: Relevance of A Disintegrin and Metalloproteinase Domain-Containing (ADAM)9 Protein Expression to Bladder Cancer Malignancy.
Autorzy:: Moriwaki M; Department of International Health, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Suma-ku, Kobe 654-0142, Japan.
Le TT; International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.
Sung SY; International Ph.D. Program for Translational Science, College of Medical Science and Technology, Taipei Medical University, 250 Wu-Hsing st, Taipei 11031 Taiwan.
Jotatsu Y; Department of International Health, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Suma-ku, Kobe 654-0142, Japan.
Yang Y; Department of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Hirata Y; Department of International Health, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Suma-ku, Kobe 654-0142, Japan.
Ishii A; Department of International Health, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Suma-ku, Kobe 654-0142, Japan.
Chiang YT; Department of Urology, Taipei Medical University Shuang Ho Hospital, 291 Zhongzheng Road, Taipei 23561, Taiwan.
Chen KC; Department of Urology, Taipei Medical University Shuang Ho Hospital, 291 Zhongzheng Road, Taipei 23561, Taiwan.
Shigemura K; Department of International Health, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Suma-ku, Kobe 654-0142, Japan.; Department of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Fujisawa M; Department of Urology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2022 Jun 06; Vol. 12 (6). Date of Electronic Publication: 2022 Jun 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: ADAM Proteins*/genetics
ADAM Proteins*/metabolism
Carcinoma*/genetics
Membrane Proteins*/genetics
Membrane Proteins*/metabolism
Urinary Bladder Neoplasms*/genetics
Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasm Invasiveness/genetics ; RNA, Messenger

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 12.

Tytuł:: Metalloendopeptidase ADAM-like Decysin 1 (ADAMDEC1) in Colonic Subepithelial PDGFRα Cells Is a New Marker for Inflammatory Bowel Disease.
Autorzy:: Ha SE; Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Jorgensen BG; Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Wei L; Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Jin B; Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Kim MS; Department of Physiology, Wonkwang Digestive Disease Research Institute and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan 54538, Korea.
Poudrier SM; Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Singh R; Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Bartlett A; Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Zogg H; Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Kim S; Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Baek G; Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Kurahashi M; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Iowa, Iowa City, IA 52242, USA.
Lee MY; Department of Physiology, Wonkwang Digestive Disease Research Institute and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan 54538, Korea.
Kim YS; Department of Physiology, Wonkwang Digestive Disease Research Institute and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan 54538, Korea.
Choi SC; Department of gastroenterology, Wonkwang Digestive Disease Research Institute and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan 54538, Korea.
Sasse KC; Sasse Surgical Associates, Reno, NV 89502, USA.
Rubin SJS; Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Gottfried-Blackmore A; Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Becker L; Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Habtezion A; Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Sanders KM; Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Ro S; Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Apr 30; Vol. 23 (9). Date of Electronic Publication: 2022 Apr 30.
Typ publikacji:: Journal Article
MeSH Terms:: ADAM Proteins*/genetics
ADAM Proteins*/metabolism
Colitis*/chemically induced
Colitis*/genetics
Colitis*/metabolism
Crohn Disease*/metabolism
Inflammatory Bowel Diseases*/diagnosis
Inflammatory Bowel Diseases*/genetics
Inflammatory Bowel Diseases*/metabolism
Animals ; Biomarkers ; Colon/cytology ; Colon/metabolism ; Intestinal Mucosa/metabolism ; Mice ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptor, Platelet-Derived Growth Factor alpha/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: A Metalloproteinase Cocktail from the Venom of Protobothrops flavoviridis Cleaves Amyloid Beta Peptides at the α-Cleavage Site.
Autorzy:: Futai E; Laboratory of Enzymology, Graduate School of Agricultural Sciences, Tohoku University, Sendai 980-8572, Japan.
Kawasaki H; Laboratory of Enzymology, Graduate School of Agricultural Sciences, Tohoku University, Sendai 980-8572, Japan.
Sato S; Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai 980-8578, Japan.
Daoudi K; Laboratory of Enzymology, Graduate School of Agricultural Sciences, Tohoku University, Sendai 980-8572, Japan.
Hidaka M; Laboratory of Enzymology, Graduate School of Agricultural Sciences, Tohoku University, Sendai 980-8572, Japan.
Tomita T; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
Ogawa T; Laboratory of Enzymology, Graduate School of Agricultural Sciences, Tohoku University, Sendai 980-8572, Japan.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2023 Aug 12; Vol. 15 (8). Date of Electronic Publication: 2023 Aug 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Amyloid beta-Peptides*
Alzheimer Disease*
Humans ; Venoms ; Proteolysis ; Brain ; Membrane Proteins ; ADAM Proteins

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: Upregulation of ADAMDEC1 correlates with tumor progression and predicts poor prognosis in non-small cell lung cancer (NSCLC) via the PI3K/AKT pathway.
Autorzy:: Zhu W; Department of Cancer Center, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Shi L; Department of Traditional Chinese Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Gong Y; Department of Traditional Chinese Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Zhuo L; Department of Traditional Chinese Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Wang S; Department of Traditional Chinese Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Chen S; Department of Traditional Chinese Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Zhang B; Department of VIP Region, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.
Ke B; Department of VIP Region, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.; Pokaż więcej
Źródło:: Thoracic cancer [Thorac Cancer] 2022 Apr; Vol. 13 (7), pp. 1027-1039. Date of Electronic Publication: 2022 Feb 17.
Typ publikacji:: Journal Article
MeSH Terms:: ADAM Proteins*/genetics
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/pathology
Cell Line, Tumor ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Humans ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Prognosis ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/genetics ; Up-Regulation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healing.
Autorzy:: Jasso GJ; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Harvard Medical School, Boston, Massachusetts, United States of America.
Jaiswal A; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
Varma M; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
Laszewski T; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America.
Grauel A; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America.
Omar A; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Silva N; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America.
Dranoff G; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America.
Porter JA; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America.
Mansfield K; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America.
Cremasco V; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America.
Regev A; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Howard Hughes Medical Institute and David H. Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
Xavier RJ; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Harvard Medical School, Boston, Massachusetts, United States of America.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.; Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
Graham DB; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Harvard Medical School, Boston, Massachusetts, United States of America.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.; Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2022 Jan 27; Vol. 20 (1), pp. e3001532. Date of Electronic Publication: 2022 Jan 27 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: ADAM Proteins/*immunology
Colitis/*immunology
Extracellular Matrix/*metabolism
Fibroblasts/*immunology
Intestinal Mucosa/*immunology
Mesenchymal Stem Cells/*immunology
ADAM Proteins/deficiency ; ADAM Proteins/genetics ; Animals ; Cell Differentiation ; Colitis/chemically induced ; Colitis/genetics ; Colitis/pathology ; Colon/immunology ; Colon/pathology ; Extracellular Matrix/immunology ; Fibroblasts/pathology ; Fibrosis ; Gene Expression Regulation ; Humans ; Inflammation ; Interleukin-11/genetics ; Interleukin-11/immunology ; Intestinal Mucosa/pathology ; Male ; Mesenchymal Stem Cells/pathology ; Mice ; Mice, Inbred C57BL ; Sequence Analysis, RNA ; Single-Cell Analysis ; Sodium Dodecyl Sulfate/administration & dosage ; Transcription, Genetic ; Transcriptome ; Wound Healing/genetics ; Wound Healing/immunology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: A Novel Pro-Inflammatory Mechanosensing Pathway Orchestrated by the Disintegrin Metalloproteinase ADAM15 in Synovial Fibroblasts.
Autorzy:: Janczi T; Division of Rheumatology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60590 Frankfurt am Main, Germany.
Meier F; Division of Rheumatology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60590 Frankfurt am Main, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, 60590 Frankfurt am Main, Germany.
Fehrl Y; Division of Rheumatology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60590 Frankfurt am Main, Germany.
Kinne RW; Experimental Rheumatology Unit, Department of Orthopedics, Jena University Hospital, Waldkliniken Eisenberg GmbH, 07607 Eisenberg, Germany.
Böhm B; Division of Rheumatology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60590 Frankfurt am Main, Germany.
Burkhardt H; Division of Rheumatology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60590 Frankfurt am Main, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, 60590 Frankfurt am Main, Germany.; Fraunhofer Cluster of Excellence Immune-Mediated Diseases CIMD, 60590 Frankfurt am Main, Germany.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Oct 09; Vol. 10 (10). Date of Electronic Publication: 2021 Oct 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: ADAM Proteins/*metabolism
Inflammation/*genetics
Mechanotransduction, Cellular/*genetics
Membrane Proteins/*metabolism
Synovial Membrane/*pathology
ADAM Proteins/genetics ; Acetylation ; Adenosine Triphosphate/metabolism ; Aged ; Calcium Signaling ; Calcium-Calmodulin-Dependent Protein Kinases/metabolism ; Connexins/metabolism ; Down-Regulation/genetics ; Humans ; Inflammation/pathology ; JNK Mitogen-Activated Protein Kinases/metabolism ; Membrane Proteins/genetics ; Middle Aged ; NAD/metabolism ; Nerve Tissue Proteins/metabolism ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Reactive Oxygen Species/metabolism ; Sirtuin 1/metabolism ; Stress, Mechanical ; TRPV Cation Channels/metabolism ; Up-Regulation/genetics

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 17.

Tytuł:: Circular RNA circNINL promotes breast cancer progression through activating β-catenin signaling via miR-921/ADAM9 axis.
Autorzy:: Xu C; Department of General Surgery, The Huangdao District People's Hospital, No. 287 Renmin Road, Qingdao, 266400 Shandong, China.
Yu H; Department of General Surgery, The Huangdao District People's Hospital, No. 287 Renmin Road, Qingdao, 266400 Shandong, China.
Yin X; Department of General Surgery, The Huangdao District People's Hospital, No. 287 Renmin Road, Qingdao, 266400 Shandong, China.
Zhang J; Department of General Surgery, The Huangdao District People's Hospital, No. 287 Renmin Road, Qingdao, 266400 Shandong, China.
Liu C; Department of General Surgery, The Huangdao District People's Hospital, No. 287 Renmin Road, Qingdao, 266400 Shandong, China.
Qi H; Department of General Surgery, Qingdao Municipal Hospital, No. 5 Middle Donghai Road, Qingdao, 266071 Shandong, China.
Liu P; Department of General Surgery, The Huangdao District People's Hospital, No. 287 Renmin Road, Qingdao, 266400 Shandong, China.; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2021 Sep 07; Vol. 169 (6), pp. 693-700.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Neoplastic*
ADAM Proteins/*metabolism
Breast Neoplasms/*pathology
Membrane Proteins/*metabolism
MicroRNAs/*genetics
Microtubule-Associated Proteins/*genetics
Nuclear Proteins/*genetics
RNA, Circular/*genetics
beta Catenin/*metabolism
ADAM Proteins/genetics ; Apoptosis ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Cell Movement ; Cell Proliferation ; Female ; Humans ; Membrane Proteins/genetics ; Middle Aged ; Prognosis ; Survival Rate ; Tumor Cells, Cultured ; beta Catenin/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: Chemotherapy-induced release of ADAM17 bearing EV as a potential resistance mechanism in ovarian cancer.
Autorzy:: Hugendieck G; Department of Gynaecology and Obstetrics, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Lettau M; Institute of Immunology, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.; Department of Hematology, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Andreas S; Department of Gynaecology and Obstetrics, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Neumann S; Department of Gynaecology and Obstetrics, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Reinhardt N; Department of Gynaecology and Obstetrics, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Arnold P; Institute of Functional and Clinical Anatomy, Friedrich-Alexander-Universität, Erlangen, Germany.
Theilig F; Institute of Anatomy, Department of Medicine, Christian-Albrechts-University, Kiel, Germany.
Bastian L; Department of Medicine II, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Rogmans C; Department of Gynaecology and Obstetrics, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Weimer JP; Department of Gynaecology and Obstetrics, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Flörkemeier I; Department of Gynaecology and Obstetrics, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Wesch D; Institute of Immunology, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Arnold N; Department of Gynaecology and Obstetrics, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Maass N; Department of Gynaecology and Obstetrics, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Janssen O; Institute of Immunology, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Bauerschlag D; Department of Gynaecology and Obstetrics, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.
Hedemann N; Department of Gynaecology and Obstetrics, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany.; Pokaż więcej
Źródło:: Journal of extracellular vesicles [J Extracell Vesicles] 2023 Jul; Vol. 12 (7), pp. e12338.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Extracellular Vesicles*/metabolism
Ovarian Neoplasms*/drug therapy
Antineoplastic Agents*
Humans ; Female ; ADAM Proteins/metabolism ; ErbB Receptors ; ADAM17 Protein

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: Preclinical Assessment of ADAM9-Responsive Mesoporous Silica Nanoparticles for the Treatment of Pancreatic Cancer.
Autorzy:: Slapak EJ; Laboratory of Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.; Oncode Institute, 3521 AZ Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology, 1081 HV Amsterdam, The Netherlands.
El Mandili M; Laboratory of Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.; Oncode Institute, 3521 AZ Amsterdam, The Netherlands.
Brink MST; Laboratory of Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Kros A; Department of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry, Leiden University, 2333 CC Leiden, The Netherlands.
Bijlsma MF; Laboratory of Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.; Oncode Institute, 3521 AZ Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology, 1081 HV Amsterdam, The Netherlands.
Spek CA; Laboratory of Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.; Cancer Center Amsterdam, Cancer Biology, 1081 HV Amsterdam, The Netherlands.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 27; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 27.
Typ publikacji:: Journal Article
MeSH Terms:: Adenocarcinoma*
Pancreatic Neoplasms*/drug therapy
Nanoparticles*
Humans ; Doxorubicin/pharmacology ; Silicon Dioxide ; Drug Delivery Systems/methods ; Paclitaxel/pharmacology ; Paclitaxel/therapeutic use ; Peptide Hydrolases ; Porosity ; Drug Carriers/pharmacology ; Membrane Proteins ; ADAM Proteins ; Pancreatic Neoplasms

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 20.

Tytuł:: The rs16969968 Tobacco Smoking-Related Single-Nucleotide Variant Is Associated with Clinical Markers in Patients with Severe COVID-19.
Autorzy:: Valencia-Pérez Rea D; HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.
Falfán-Valencia R; HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.
Fricke-Galindo I; HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.
Buendía-Roldán I; Translational Research Laboratory on Aging and Pulmonary Fibrosis, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.
Chávez-Galán L; Laboratory of Integrative Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.
Nava-Quiroz KJ; HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.
Alanis-Ponce J; HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.
Pérez-Rubio G; HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 06; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 06.
Typ publikacji:: Journal Article
MeSH Terms:: Receptors, Nicotinic*/genetics
COVID-19*/genetics
Humans ; C-Reactive Protein/genetics ; Polymorphism, Single Nucleotide ; Tobacco Smoking ; Biomarkers ; Fibrinogen/genetics ; Nucleotides ; Genetic Predisposition to Disease ; ADAM Proteins/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Informacja

Wyszukujesz frazę ""ADAM Proteins"" wg kryterium: Temat

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat

Wydawca

Publikacja

Język