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Wyszukujesz frazę ""ADENOSINE"" wg kryterium: Temat


Tytuł:
Elevated CD39+T-Regulatory Cells and Reduced Levels of Adenosine Indicate a Role for Tolerogenic Signals in the Progression from Moderate to Severe COVID-19.
Autorzy:
Elsaghir A; Department of Microbiology & Immunology, Faculty of Pharmacy, Assiut University, Assiut 71515, Egypt.
El-Sabaa EMW; Department of Microbiology & Immunology, Faculty of Pharmacy, Assiut University, Assiut 71515, Egypt.
Zahran AM; Department of Clinical Pathology, South Egypt Cancer Institute, Assiut University, Assiut 71515, Egypt.
Mandour SA; Department of Microbiology and Immunology, Faculty of Pharmacy, Deraya University, Minia 11566, Egypt.
Salama EH; Department of Clinical Pathology, Faculty of Medicine, Sohag University, Sohag 82524, Egypt.
Aboulfotuh S; Department of Clinical Pathology, Faculty of Medicine, Sohag University, Sohag 82524, Egypt.
El-Morshedy RM; Department of Chest Diseases and Tuberculosis, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.
Tocci S; Department of Biomedical & Nutritional Sciences, Zuckerberg College of Health Sciences, University of Massachusetts Lowell, Lowell, MA 01854, USA.
Mandour AM; Department of Anesthesia and ICU, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.
Ali WE; Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Assiut Branch, Assiut 71524, Egypt.
Abdel-Wahid L; Gastroenterology and Hepatology Unit, Internal Medicine Department, Assiut University, Assiut 71515, Egypt.
Sayed IM; Department of Biomedical & Nutritional Sciences, Zuckerberg College of Health Sciences, University of Massachusetts Lowell, Lowell, MA 01854, USA.
El-Mokhtar MA; Gilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos P.O. Box 36, Lebanon.; Department of Medical Microbiology & Immunology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 18; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:
Journal Article
MeSH Terms:
Adenosine*/metabolism
COVID-19*
T-Lymphocytes, Regulatory*/metabolism
Humans ; 5'-Nucleotidase/genetics ; 5'-Nucleotidase/metabolism ; Adenosine Triphosphate/metabolism ; Anti-Inflammatory Agents ; Antigens, CD/genetics ; Antigens, CD/metabolism ; Disease Progression ; Interleukin-10 ; Receptors, Purinergic P1/genetics ; Transforming Growth Factor beta/genetics
Czasopismo naukowe
Tytuł:
The Immune Regulatory Role of Adenosine in the Tumor Microenvironment.
Autorzy:
Xing J; Department of Immunology, School of Basic Medicine, China Medical University, Shenyang 100001, China.; College of Life Science and Bioengineering, Beijing Jiaotong University, Beijing 100044, China.
Zhang J; College of Life Science and Bioengineering, Beijing Jiaotong University, Beijing 100044, China.
Wang J; Department of Immunology, School of Basic Medicine, China Medical University, Shenyang 100001, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 05; Vol. 24 (19). Date of Electronic Publication: 2023 Oct 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Adenosine*/metabolism
Neoplasms*/metabolism
Humans ; Tumor Microenvironment ; Adenosine Triphosphate/metabolism ; CD8-Positive T-Lymphocytes ; T-Lymphocytes, Regulatory ; 5'-Nucleotidase/metabolism
Czasopismo naukowe
Tytuł:
Functional Interaction between Adenosine A 2A and mGlu 5 Receptors Mediates STEP Phosphatase Activation and Promotes STEP/mGlu 5 R Binding in Mouse Hippocampus and Neuroblastoma Cell Line.
Autorzy:
Mallozzi C; Department of Neuroscience, Istituto Superiore di Sanità, 00161 Rome, Italy.
Pepponi R; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Gaddini L; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Casella I; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Chiodi V; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Popoli P; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Domenici MR; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
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Źródło:
Biomolecules [Biomolecules] 2023 Sep 05; Vol. 13 (9). Date of Electronic Publication: 2023 Sep 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptor, Adenosine A2A*/metabolism
Neuroblastoma*
Humans ; Mice ; Animals ; Receptor, Metabotropic Glutamate 5/metabolism ; Adenosine/pharmacology ; Cell Line ; Hippocampus/metabolism
Czasopismo naukowe
Tytuł:
RNA Editing-Dependent and -Independent Roles of Adenosine Deaminases Acting on RNA Proteins in Herpesvirus Infection-Hints on Another Layer of Complexity.
Autorzy:
Ivanišević V; Department of Biotechnology, University of Rijeka, 51000 Rijeka, Croatia.
Žilić L; Department of Biotechnology, University of Rijeka, 51000 Rijeka, Croatia.
Čunko M; Department of Biotechnology, University of Rijeka, 51000 Rijeka, Croatia.
Fadiga H; Department of Biotechnology, University of Rijeka, 51000 Rijeka, Croatia.
Munitić I; Department of Biotechnology, University of Rijeka, 51000 Rijeka, Croatia.
Jurak I; Department of Biotechnology, University of Rijeka, 51000 Rijeka, Croatia.
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Źródło:
Viruses [Viruses] 2023 Sep 27; Vol. 15 (10). Date of Electronic Publication: 2023 Sep 27.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenosine Deaminase*/metabolism
Herpesviridae Infections*
Humans ; RNA Editing ; RNA, Double-Stranded ; Adenosine/metabolism
Czasopismo naukowe
Tytuł:
Adenosine metabolized from extracellular ATP ameliorates organ injury by triggering A 2B R signaling.
Autorzy:
Kelestemur T; Department of Anesthesiology, Columbia University, 630 W 168th Street, New York City, NY, 10032, USA.; Department of Physiology, Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey.
Németh ZH; Department of Anesthesiology, Columbia University, 630 W 168th Street, New York City, NY, 10032, USA.; Department of Surgery, Morristown Medical Center, Morristown, NJ, 07960, USA.
Pacher P; Laboratory of Cardiovascular Physiology and Tissue Injury, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Beesley J; Daresbury Proteins Ltd, Sci-Tech Daresbury, Warrington, UK.
Robson SC; Department of Anesthesia, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Eltzschig HK; Department of Anesthesiology, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Haskó G; Department of Anesthesiology, Columbia University, 630 W 168th Street, New York City, NY, 10032, USA. .
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Źródło:
Respiratory research [Respir Res] 2023 Jul 13; Vol. 24 (1), pp. 186. Date of Electronic Publication: 2023 Jul 13.
Typ publikacji:
Journal Article
MeSH Terms:
Adenosine*
Multiple Organ Failure*
Animals ; Mice ; Adenosine Triphosphate ; Signal Transduction ; Bronchoalveolar Lavage Fluid
Czasopismo naukowe
Tytuł:
A2BAR Antagonism Decreases the Glomerular Expression and Secretion of Chemoattractants for Monocytes and the Pro-Fibrotic M2 Macrophages Polarization during Diabetic Nephropathy.
Autorzy:
Torres-Arévalo Á; Escuela de Medicina Veterinaria, Facultad de Medicina Veterinaria Y Recursos Naturales, Sede Talca, Universidad Santo Tomás, Talca 347-3620, Chile.
Nahuelpán Y; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Muñoz K; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Jara C; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Cappelli C; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Taracha-Wiśniewska A; Faculty of Biology, Institute of Genetics and Biotechnology, University of Warsaw, 02-106 Warsaw, Poland.
Quezada-Monrás C; Tumor Biology Laboratory, Institute of Biochemistry and Microbiology, Faculty of Sciences, Universidad Austral de Chile, Valdivia 511-0566, Chile.; Millennium Institute on Immunology and Immunotherapy, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Martín RS; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 29; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 29.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetic Nephropathies*/genetics
Diabetic Nephropathies*/immunology
Kidney Glomerulus*/drug effects
Kidney Glomerulus*/metabolism
Chemotactic Factors*/antagonists & inhibitors
Chemotactic Factors*/genetics
Chemotactic Factors*/metabolism
Cell Polarity*/drug effects
Cell Polarity*/immunology
Macrophages*/drug effects
Macrophages*/immunology
Adenosine A2 Receptor Antagonists*/pharmacology
Acetamides*/pharmacology
Purines*/pharmacology
Receptor, Adenosine A2B ; Animals ; Rats ; Cell Movement/drug effects ; Male ; Rats, Sprague-Dawley ; Transcription, Genetic/drug effects ; Protein Biosynthesis/drug effects ; Immunity/drug effects ; Immunity/genetics
Czasopismo naukowe
Tytuł:
The role of the ATP-adenosine axis in ischemic stroke.
Autorzy:
Schädlich IS; Department of Neurology, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Winzer R; Institute of Immunology, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Stabernack J; Department of Neurology, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Tolosa E; Institute of Immunology, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Magnus T; Department of Neurology, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany. .
Rissiek B; Department of Neurology, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
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Źródło:
Seminars in immunopathology [Semin Immunopathol] 2023 May; Vol. 45 (3), pp. 347-365. Date of Electronic Publication: 2023 Mar 14.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenosine Triphosphate*
Ischemic Stroke*
Humans ; Adenosine ; Inflammation ; Signal Transduction
Czasopismo naukowe
Tytuł:
C2-linked alkynyl poly-ethylene glycol(PEG) adenosine conjugates as water-soluble adenosine receptor agonists.
Autorzy:
Ferguson L; School of Science, University of the West of Scotland, Paisley, UK.
Madieh NS; Leicester School of Pharmacy, De Montfort University, Leicester, UK.
Vaideanu A; UCL School of Pharmacy, University College London, London, UK.
Schatzlein A; UCL School of Pharmacy, University College London, London, UK.
Festa J; Leicester School of Allied Health Sciences, De Montfort University, Leicester, UK.
Singh H; Leicester School of Allied Health Sciences, De Montfort University, Leicester, UK.
Wells G; UCL School of Pharmacy, University College London, London, UK.
Bhakta S; Department of Biological Sciences, Institute of Structural and Molecular Biology, Birkbeck, University of London, London, UK.
Brucoli F; Leicester School of Pharmacy, De Montfort University, Leicester, UK.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2023 Feb; Vol. 101 (2), pp. 340-349. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenosine*/pharmacology
Adenosine*/metabolism
Purinergic P1 Receptor Agonists*
Mice ; Animals ; Polyethylene Glycols ; Receptors, Purinergic P1/metabolism ; Protein Binding ; Receptor, Adenosine A2A/metabolism ; Receptor, Adenosine A3
Czasopismo naukowe
Tytuł:
Adenosine A 2A Receptors Shut Down Adenosine A 1 Receptor-Mediated Presynaptic Inhibition to Promote Implementation of Hippocampal Long-Term Potentiation.
Autorzy:
Lopes CR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Gonçalves FQ; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Olaio S; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Tomé AR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3004-504 Coimbra, Portugal.
Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3000-534 Coimbra, Portugal.
Lopes JP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
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Źródło:
Biomolecules [Biomolecules] 2023 Apr 21; Vol. 13 (4). Date of Electronic Publication: 2023 Apr 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Long-Term Potentiation*
Receptor, Adenosine A2A*/metabolism
Adenosine/pharmacology ; Hippocampus/metabolism ; Synaptic Transmission ; Animals ; Mice
Czasopismo naukowe
Tytuł:
Increased Density of Endogenous Adenosine A 2A Receptors in Atrial Fibrillation: From Cellular and Porcine Models to Human Patients.
Autorzy:
Godoy-Marín H; Pharmacology Unit, Department of Pathology and Experimental Therapeutics, School of Medicine and Health Sciences, Institute of Neurosciences, University of Barcelona, 08907 L'Hospitalet de Llobregat, Spain.; Neuropharmacology & Pain Group, Neuroscience Program, Bellvitge Institute for Biomedical Research, 08907 L'Hospitalet de Llobregat, Spain.
Jiménez-Sábado V; Biomedical Research Institute Sant Pau, IIB Sant Pau, 08025 Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares, 28029 Madrid, Spain.
Tarifa C; Biomedical Research Institute Sant Pau, IIB Sant Pau, 08025 Barcelona, Spain.; Biomedical Research Institute of Barcelona, IIBB-CSIC, 08036 Barcelona, Spain.
Ginel A; Department Cardiac Surgery, Hospital de la Santa Creu i Sant Pau, 08036 Barcelona, Spain.
Santos JLD; Department of Biomedical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Bentzen BH; Department of Biomedical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Hove-Madsen L; Biomedical Research Institute Sant Pau, IIB Sant Pau, 08025 Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares, 28029 Madrid, Spain.; Biomedical Research Institute of Barcelona, IIBB-CSIC, 08036 Barcelona, Spain.
Ciruela F; Pharmacology Unit, Department of Pathology and Experimental Therapeutics, School of Medicine and Health Sciences, Institute of Neurosciences, University of Barcelona, 08907 L'Hospitalet de Llobregat, Spain.; Neuropharmacology & Pain Group, Neuroscience Program, Bellvitge Institute for Biomedical Research, 08907 L'Hospitalet de Llobregat, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 11; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 11.
Typ publikacji:
Journal Article
MeSH Terms:
Atrial Fibrillation*/metabolism
Receptor, Adenosine A2A*/metabolism
Animals ; Humans ; Adenosine/metabolism ; Heart Atria/metabolism ; Leukocytes, Mononuclear/metabolism ; Myocytes, Cardiac/metabolism ; Swine
Czasopismo naukowe
Tytuł:
F 1 ·F o ATP Synthase/ATPase: Contemporary View on Unidirectional Catalysis.
Autorzy:
Zharova TV; Department of Biochemistry, Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Grivennikova VG; Department of Biochemistry, Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Borisov VB; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory, 119991 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 12; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Adenosine Triphosphatases*/metabolism
Membrane Proteins*/metabolism
Nitric Oxide Synthase/metabolism ; Adenosine Triphosphate/metabolism ; Catalysis ; Proton-Translocating ATPases/metabolism ; Hydrolysis
Czasopismo naukowe
Tytuł:
Real-Time Visualization of Cytosolic and Mitochondrial ATP Dynamics in Response to Metabolic Stress in Cultured Cells.
Autorzy:
White D 3rd; Cardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; Department of Pharmacology and Experimental Therapeutics, School of Graduate Studies, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Lauterboeck L; Cardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; Department of Pharmacology and Experimental Therapeutics, School of Graduate Studies, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; Cell Biology, Life Science Solutions, Thermo Fisher Scientific, Frederick, MD 21702, USA.
Mobasheran P; Cardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; Department of Pharmacology and Experimental Therapeutics, School of Graduate Studies, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Kitaguchi T; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Kanagawa, Japan.
Chaanine AH; HealthPartners Group, Regions Hospital, Saint Paul, MN 55101, USA.
Yang Q; Cardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; Department of Pharmacology and Experimental Therapeutics, School of Graduate Studies, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
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Źródło:
Cells [Cells] 2023 Feb 22; Vol. 12 (5). Date of Electronic Publication: 2023 Feb 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Adenosine Triphosphate*/metabolism
Stress, Physiological*
Humans ; Cytosol/metabolism ; HEK293 Cells ; Adenosine Diphosphate/metabolism ; Atractyloside/metabolism ; Oligomycins
Czasopismo naukowe
Tytuł:
Synthesis, QSAR modeling, and molecular docking of novel fused 7-deazaxanthine derivatives as adenosine A 2A receptor antagonists.
Autorzy:
Muzychka LV; Department of Chemistry of Natural Compounds, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv, Ukraine.
Verves EV; Department of Chemistry of Natural Compounds, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv, Ukraine.; Enamine Ltd, Kyiv, Ukraine.
Yaremchuk IO; Department of Chemistry of Natural Compounds, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv, Ukraine.
Zinchenko AM; Department of Chemistry of Natural Compounds, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv, Ukraine.
Shishkina SV; Department of X-ray Diffraction Studies and Quantum Chemistry, STC 'Institute for Single Crystals', NAS of Ukraine, Kharkiv, Ukraine.
Semenyuta IV; Department of Medical and Biological Researches, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv, Ukraine.
Hodyna DM; Department of Medical and Biological Researches, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv, Ukraine.
Metelytsia LO; Department of Medical and Biological Researches, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv, Ukraine.
Kovalishyn V; Department of Medical and Biological Researches, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv, Ukraine.
Smolii OB; Department of Chemistry of Natural Compounds, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, NAS of Ukraine, Kyiv, Ukraine.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2022 Dec; Vol. 100 (6), pp. 1025-1032. Date of Electronic Publication: 2021 Oct 19.
Typ publikacji:
Journal Article
MeSH Terms:
Quantitative Structure-Activity Relationship*
Receptor, Adenosine A2A*
Molecular Docking Simulation ; Adenosine ; Adenosine A2 Receptor Antagonists/pharmacology
Czasopismo naukowe
Tytuł:
Purinergic Signalling in the Cochlea.
Autorzy:
Vlajkovic SM; Department of Physiology and The Eisdell Moore Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Thorne PR; Department of Physiology and The Eisdell Moore Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.; Section of Audiology, School of Population Health, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 28; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Adenosine Triphosphate*/metabolism
Cochlea*/metabolism
Animals ; Hearing/physiology ; Signal Transduction/physiology ; Adenosine/metabolism ; Mammals/metabolism
Czasopismo naukowe
Tytuł:
CD73-Mediated Formation of Extracellular Adenosine Is Responsible for Adenosine A 2A Receptor-Mediated Control of Fear Memory and Amygdala Plasticity.
Autorzy:
Simões AP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Gonçalves FQ; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Rial D; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Ferreira SG; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Lopes JP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Canas PM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 24; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 24.
Typ publikacji:
Journal Article
MeSH Terms:
5'-Nucleotidase*/genetics
5'-Nucleotidase*/metabolism
Receptor, Adenosine A2A*/genetics
Receptor, Adenosine A2A*/metabolism
Mice ; Animals ; Adenosine/metabolism ; Mice, Inbred C57BL ; Amygdala/metabolism ; Mice, Knockout ; Fear/physiology ; Adenosine Diphosphate ; Adenosine Triphosphate/metabolism
Czasopismo naukowe
Tytuł:
Radiosynthesis and In Vitro Evaluation of [ C]tozadenant as Adenosine A 2A Receptor Radioligand.
Autorzy:
Humpert S; Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medicine, Nuclear Chemistry (INM-5), Wilhelm-Johnen-Str., 52428 Jülich, Germany.
Schneider D; Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medicine, Nuclear Chemistry (INM-5), Wilhelm-Johnen-Str., 52428 Jülich, Germany.
Lang M; Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medicine, Nuclear Chemistry (INM-5), Wilhelm-Johnen-Str., 52428 Jülich, Germany.
Schulze A; Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medicine, Nuclear Chemistry (INM-5), Wilhelm-Johnen-Str., 52428 Jülich, Germany.
Neumaier F; Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medicine, Nuclear Chemistry (INM-5), Wilhelm-Johnen-Str., 52428 Jülich, Germany.; Institute of Radiochemistry and Experimental Molecular Imaging, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.
Holschbach M; Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medicine, Nuclear Chemistry (INM-5), Wilhelm-Johnen-Str., 52428 Jülich, Germany.
Bier D; Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medicine, Nuclear Chemistry (INM-5), Wilhelm-Johnen-Str., 52428 Jülich, Germany.
Neumaier B; Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medicine, Nuclear Chemistry (INM-5), Wilhelm-Johnen-Str., 52428 Jülich, Germany.; Institute of Radiochemistry and Experimental Molecular Imaging, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 29; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
Receptor, Adenosine A2A*/metabolism
Brain*/metabolism
Rats ; Animals ; Swine ; Benzothiazoles/metabolism ; Positron-Emission Tomography/methods ; Radiopharmaceuticals
Czasopismo naukowe
Tytuł:
Adenosine in Intestinal Epithelial Barrier Function.
Autorzy:
Stepanova M; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.; School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
Aherne CM; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.; School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
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Źródło:
Cells [Cells] 2024 Feb 23; Vol. 13 (5). Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Adenosine*
Inflammatory Bowel Diseases*
Humans ; Inflammation ; Intestinal Mucosa
Czasopismo naukowe
Tytuł:
ADP-Ribosylation and Antiviral Resistance in Plants.
Autorzy:
Spechenkova N; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, 117997 Moscow, Russia.
Kalinina NO; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, 117997 Moscow, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
Zavriev SK; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, 117997 Moscow, Russia.
Love AJ; The James Hutton Institute, Invergowrie, Dundee DD2 5DA, UK.
Taliansky M; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, 117997 Moscow, Russia.; The James Hutton Institute, Invergowrie, Dundee DD2 5DA, UK.
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Źródło:
Viruses [Viruses] 2023 Jan 14; Vol. 15 (1). Date of Electronic Publication: 2023 Jan 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Poly(ADP-ribose) Polymerases*/genetics
Poly Adenosine Diphosphate Ribose*/metabolism
Poly(ADP-ribose) Polymerase Inhibitors ; ADP-Ribosylation ; Adenosine Diphosphate Ribose/metabolism ; Antiviral Agents/pharmacology
Czasopismo naukowe
Tytuł:
Biochemical and Structural Analyses Shed Light on the Mechanisms of RadD DNA Binding and Its ATPase from Escherichia coli .
Autorzy:
Tian LF; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Kuang X; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Ding K; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Gao H; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Tang Q; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Yan XX; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Xu W; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 01; Vol. 24 (1). Date of Electronic Publication: 2023 Jan 01.
Typ publikacji:
Journal Article
MeSH Terms:
Adenosine Triphosphatases*/metabolism
Escherichia coli*/genetics
Escherichia coli*/metabolism
Escherichia coli Proteins*/metabolism
Adenosine Triphosphate/metabolism ; Binding Sites ; DNA/metabolism ; Molecular Docking Simulation ; Protein Binding
Czasopismo naukowe
Tytuł:
Design and synthesis of five-membered heterocyclic derivatives of istradefylline with comparable pharmacological activity.
Autorzy:
Wang Y; School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, China.; Shandong Xinhua Pharmaceutical Co., Ltd, Zibo, China.
Wang H; Shandong Xinhua Pharmaceutical Co., Ltd, Zibo, China.
Xu H; Shandong Xinhua Pharmaceutical Co., Ltd, Zibo, China.
Zheng Z; Shandong Xinhua Pharmaceutical Co., Ltd, Zibo, China.
Meng Z; School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, China.
Xu Z; School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, China.
Li J; School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, China.
Xue M; School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, China.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2022 Oct; Vol. 100 (4), pp. 534-552. Date of Electronic Publication: 2022 May 30.
Typ publikacji:
Journal Article
MeSH Terms:
Adenosine A2 Receptor Antagonists*/pharmacology
Parkinson Disease*
Adenosine ; Aged ; Benzothiazoles/pharmacology ; Humans ; Molecular Docking Simulation ; Purines ; Receptor, Adenosine A2A ; Xanthines
Czasopismo naukowe

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