Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""AGONIST"" wg kryterium: Temat


Tytuł:
Direct Measurement of the Affinity between tBid and Bax in a Mitochondria-Like Membrane.
Autorzy:
Rose M; Department of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4M1, Canada.
Kurylowicz M; Department of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4M1, Canada.
Mahmood M; Department of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4M1, Canada.
Winkel S; Department of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4M1, Canada.
Moran-Mirabal JM; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, ON L8S 4M1, Canada.
Fradin C; Department of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4M1, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 31; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 31.
Typ publikacji:
Journal Article
MeSH Terms:
BH3 Interacting Domain Death Agonist Protein/*chemistry
Lipid Bilayers/*chemistry
bcl-2-Associated X Protein/*chemistry
Animals ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Humans ; Lipid Bilayers/metabolism ; Mice ; Protein Binding ; Protein Conformation ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1.
Autorzy:
Lim D; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Department of Biochemistry, Chungnam National University, Daejeon, Korea.
Choe SH; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.
Jin S; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.
Lee S; Department of Biochemistry, Chungnam National University, Daejeon, Korea.
Kim Y; Department of Biochemistry, Chungnam National University, Daejeon, Korea.
Shin HC; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.
Choi JS; Department of Biochemistry, Chungnam National University, Daejeon, Korea.
Oh DB; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Department of Biosystems and Bioengineering, KRIBB School of Biotechnology, University of Science and Technology, Daejeon, Korea.
Kim SJ; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Department of Proteome Structural Biology, KRIBB School of Bioscience, University of Science and Technology, Daejeon, Korea.
Seo J; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Department of Biosystems and Bioengineering, KRIBB School of Biotechnology, University of Science and Technology, Daejeon, Korea.
Ku B; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Department of Proteome Structural Biology, KRIBB School of Bioscience, University of Science and Technology, Daejeon, Korea.
Pokaż więcej
Źródło:
PLoS biology [PLoS Biol] 2023 Jun 14; Vol. 21 (6), pp. e3002156. Date of Electronic Publication: 2023 Jun 14 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Proto-Oncogene Proteins c-bcl-2*
Humans ; Male ; Apoptosis/physiology ; bcl-2-Associated X Protein ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Carrier Proteins/metabolism ; Mitochondria/metabolism
Czasopismo naukowe
Tytuł:
Polyethyleneimine-polyethylene glycol copolymer targeted by anti-HER2 nanobody for specific delivery of transcriptionally targeted tBid containing construct.
Autorzy:
Saqafi B; a Faculty of Medical Sciences, Department of Medical Biotechnology , Tarbiat Modares University , Tehran , Iran.
Rahbarizadeh F; a Faculty of Medical Sciences, Department of Medical Biotechnology , Tarbiat Modares University , Tehran , Iran.
Pokaż więcej
Źródło:
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2019 Dec; Vol. 47 (1), pp. 501-511.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents, Immunological*/chemistry
Antineoplastic Agents, Immunological*/pharmacology
BH3 Interacting Domain Death Agonist Protein*/biosynthesis
BH3 Interacting Domain Death Agonist Protein*/genetics
Gene Transfer Techniques*
Genetic Therapy*
Polyethylene Glycols*/chemistry
Polyethylene Glycols*/pharmacology
Single-Domain Antibodies*/chemistry
Single-Domain Antibodies*/pharmacology
Polyethyleneimine/*analogs & derivatives
Receptor, ErbB-2/*antagonists & inhibitors
Transcription, Genetic/*drug effects
Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/therapy ; Female ; Humans ; Polyethyleneimine/chemistry ; Polyethyleneimine/pharmacology ; Receptor, ErbB-2/genetics ; Receptor, ErbB-2/metabolism
Czasopismo naukowe
Tytuł:
TRAF3/p38-JNK Signalling Crosstalk with Intracellular-TRAIL/Caspase-10-Induced Apoptosis Accelerates ROS-Driven Cancer Cell-Specific Death by CD40.
Autorzy:
Ibraheem K; Department of Biological Sciences, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
Yhmed AMA; Department of Biological Sciences, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.; Department of Medical Laboratory Sciences, Faculty of Medical Technology, Wadi Alshatti University, Wadi Alshatti P.O. Box 68, Libya.
Nasef MM; Department of Biological Sciences, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
Georgopoulos NT; Department of Biological Sciences, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
Pokaż więcej
Źródło:
Cells [Cells] 2022 Oct 18; Vol. 11 (20). Date of Electronic Publication: 2022 Oct 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
CD40 Antigens*/metabolism
Reactive Oxygen Species*/metabolism
TNF Receptor-Associated Factor 3*/metabolism
TNF-Related Apoptosis-Inducing Ligand*/metabolism
p38 Mitogen-Activated Protein Kinases*/metabolism
MAP Kinase Kinase 4*
Colorectal Neoplasms*/metabolism
Colorectal Neoplasms*/pathology
Humans ; Caspase 10/metabolism ; CD40 Ligand/metabolism ; MAP Kinase Kinase Kinase 5/metabolism ; NADPH Oxidases/metabolism ; BH3 Interacting Domain Death Agonist Protein/metabolism
Czasopismo naukowe
Tytuł:
Evaluating the impact of efpeglenatide on cardiometabolic and safety outcomes in individuals with diabetes: a systematic review and meta-analysis
Autorzy:
Qazi, Shurjeel UddinAff1, Aff3, IDs40200024014093_cor1
Ansari, Huzaifa Ul Haq
Tharwani, Zoaib Habib
Altaf, Zahabia
Noman, Ayesha
Ghazanfar, Shamas
Kumar, Sangeet
Ansari, Haya Waseem
Nasir, Muhammad Moiz
Qazi, Sana
Pokaż więcej
Źródło:
Journal of Diabetes & Metabolic Disorders. :1-11
Czasopismo naukowe
Tytuł:
Immediate Impact of Switching from Dipeptidyl Peptidase 4 (DPP4) Inhibitors to Low-Dose (0.3 mg) Liraglutide on Glucose Profiles: A Retrospective Observational Study
Autorzy:
Terui, Sakiko
Igari, Mari
Tsuno, Takahiro
Okuyama, Tomoko
Inoue, Ryota
Kyohara, Mayu
Terauchi, Yasuo
Shirakawa, JunAff1, Aff2, IDs1330002401557y_cor8
Pokaż więcej
Źródło:
Diabetes Therapy: Research, treatment and education of diabetes and related disorders. :1-15
Czasopismo naukowe
Tytuł:
LH supplementation in IVF: human nature, politics, and elephants in the room
Autorzy:
Castillo, Juan
Quaas, Alexander M.
Kol, ShaharAff3, IDs10815024030339_cor3
Pokaż więcej
Źródło:
Journal of Assisted Reproduction and Genetics: An Official Journal of the American Society for Reproductive Medicine. 41(3):609-612
Czasopismo naukowe
Tytuł:
Real-World Use of Oral Semaglutide in Adults with Type 2 Diabetes: The PIONEER REAL Switzerland Multicentre, Prospective, Observational Study
Autorzy:
Kick, Anastas
M’Rabet-Bensalah, Khadija
Acquistapace, Flavio
Amadid, Hanan
Ambühl, Robert A.
Braae, Uffe Christian
Item, Flurin
Schultes, Bernd
Züger, Thomas
Rudofsky, GottfriedAff7, Aff8, IDs1330002301525y_cor10
Pokaż więcej
Źródło:
Diabetes Therapy: Research, treatment and education of diabetes and related disorders. 15(3):623-637
Czasopismo naukowe
Tytuł:
Dose–response effects on HbA1c and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial
Autorzy:
Blüher, MatthiasAff1, IDs00125023060539_cor1
Rosenstock, Julio
Hoefler, Josef
Manuel, Raymond
Hennige, Anita M.Aff5, IDs00125023060539_cor5
Pokaż więcej
Źródło:
Diabetologia: Clinical, Translational and Experimental Diabetes and Metabolism. 67(3):470-482
Czasopismo naukowe
Tytuł:
HSK3486 Inhibits Colorectal Cancer Growth by Promoting Oxidative Stress and ATPase Inhibitory Factor 1 Activation
Autorzy:
Nan, KeAff1, Aff2, Aff3
Zhong, ZiwenAff1, Aff2, Aff3
Yue, YingAff1, Aff2, Aff3
Zhou, WenchangAff1, Aff2, Aff3
Sun, XingfengAff1, Aff2, Aff3, Aff4
Shen, YangAff1, Aff2, Aff3
Qu, MengdiAff1, Aff2, Aff3
Chen, ZhaoyuanAff1, Aff2, Aff3
Gu, JiahuiAff1, Aff2, Aff3
Sun, CaihongAff1, Aff2, Aff3
Sun, Xun
Lu, LihongAff1, Aff2, Aff3, Aff6
Zhang, JieAff1, Aff2, Aff3
Miao, ChanghongAff1, Aff2, Aff3
Sun, MinliAff1, Aff2, Aff3, IDs10620023082138_cor15
Pokaż więcej
Źródło:
Digestive Diseases and Sciences. :1-14
Czasopismo naukowe
Tytuł:
Impulse control disorders in patients with dopamine agonist-treated pituitary adenomas: a cross-sectional multicenter study
Autorzy:
Almalki, Mussa H.Aff1, Aff2
Alsuraikh, Moayad A.
Almalki, Eyad
Aziz, Faisal
Almazrouei, RayaAff5, Aff6
AlDahmani, Khaled MAff5, Aff6
Alshahrani, FahadAff7, Aff8
Alaqeel, MeshalAff7, Aff8, Aff9
Mahzari, MoeberAff7, Aff8, Aff10, IDs11102024013832_cor9
Ekhzaimy, Aishah
Pokaż więcej
Źródło:
Pituitary: The official publication of the Pituitary Society and the Growth Hormone Research Society. :1-7
Czasopismo naukowe
Tytuł:
Efficacy and Safety of Once-Weekly Semaglutide Versus Once-Daily Sitagliptin as Metformin Add-on in a Korean Population with Type 2 Diabetes
Autorzy:
Lee, Byung-Wan
Cho, Young Min
Kim, Sin Gon
Ko, Seung-Hyun
Lim, Soo
Dahaoui, Amine
Jeong, Jin Sook
Lim, Hyo Jin
Yu, Jae MyungAff8, IDs13300023015150_cor9
Pokaż więcej
Źródło:
Diabetes Therapy: Research, treatment and education of diabetes and related disorders. 15(2):547-563
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies