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Tytuł :
A Randomized Trial of Albumin Infusions in Hospitalized Patients with Cirrhosis.
Autorzy :
China L; From the Institute for Liver and Digestive Health (L.C., N.B.S., A.O.), the Comprehensive Clinical Trials Unit (N.F.), and the Division of Medicine, University College London (D.W.G.), Barts and the London School of Medicine and Dentistry, Queen Mary University of London (Y.K.), London, the Glasgow Royal Infirmary and the University of Glagow, Glasgow (E.F.), the National Institute for Health Research Nottingham Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Nottingham (S.D.R.), the Mid and South Essex NHS Foundation Trust and the Basildon and Thurrock University Hospitals NHS Foundation Trust, Basildon (G.W.), and the Bristol Royal Infirmary, Bristol (A.J.P.) - all in the United Kingdom.
Freemantle N; From the Institute for Liver and Digestive Health (L.C., N.B.S., A.O.), the Comprehensive Clinical Trials Unit (N.F.), and the Division of Medicine, University College London (D.W.G.), Barts and the London School of Medicine and Dentistry, Queen Mary University of London (Y.K.), London, the Glasgow Royal Infirmary and the University of Glagow, Glasgow (E.F.), the National Institute for Health Research Nottingham Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Nottingham (S.D.R.), the Mid and South Essex NHS Foundation Trust and the Basildon and Thurrock University Hospitals NHS Foundation Trust, Basildon (G.W.), and the Bristol Royal Infirmary, Bristol (A.J.P.) - all in the United Kingdom.
Forrest E; From the Institute for Liver and Digestive Health (L.C., N.B.S., A.O.), the Comprehensive Clinical Trials Unit (N.F.), and the Division of Medicine, University College London (D.W.G.), Barts and the London School of Medicine and Dentistry, Queen Mary University of London (Y.K.), London, the Glasgow Royal Infirmary and the University of Glagow, Glasgow (E.F.), the National Institute for Health Research Nottingham Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Nottingham (S.D.R.), the Mid and South Essex NHS Foundation Trust and the Basildon and Thurrock University Hospitals NHS Foundation Trust, Basildon (G.W.), and the Bristol Royal Infirmary, Bristol (A.J.P.) - all in the United Kingdom.
Kallis Y; From the Institute for Liver and Digestive Health (L.C., N.B.S., A.O.), the Comprehensive Clinical Trials Unit (N.F.), and the Division of Medicine, University College London (D.W.G.), Barts and the London School of Medicine and Dentistry, Queen Mary University of London (Y.K.), London, the Glasgow Royal Infirmary and the University of Glagow, Glasgow (E.F.), the National Institute for Health Research Nottingham Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Nottingham (S.D.R.), the Mid and South Essex NHS Foundation Trust and the Basildon and Thurrock University Hospitals NHS Foundation Trust, Basildon (G.W.), and the Bristol Royal Infirmary, Bristol (A.J.P.) - all in the United Kingdom.
Ryder SD; From the Institute for Liver and Digestive Health (L.C., N.B.S., A.O.), the Comprehensive Clinical Trials Unit (N.F.), and the Division of Medicine, University College London (D.W.G.), Barts and the London School of Medicine and Dentistry, Queen Mary University of London (Y.K.), London, the Glasgow Royal Infirmary and the University of Glagow, Glasgow (E.F.), the National Institute for Health Research Nottingham Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Nottingham (S.D.R.), the Mid and South Essex NHS Foundation Trust and the Basildon and Thurrock University Hospitals NHS Foundation Trust, Basildon (G.W.), and the Bristol Royal Infirmary, Bristol (A.J.P.) - all in the United Kingdom.
Wright G; From the Institute for Liver and Digestive Health (L.C., N.B.S., A.O.), the Comprehensive Clinical Trials Unit (N.F.), and the Division of Medicine, University College London (D.W.G.), Barts and the London School of Medicine and Dentistry, Queen Mary University of London (Y.K.), London, the Glasgow Royal Infirmary and the University of Glagow, Glasgow (E.F.), the National Institute for Health Research Nottingham Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Nottingham (S.D.R.), the Mid and South Essex NHS Foundation Trust and the Basildon and Thurrock University Hospitals NHS Foundation Trust, Basildon (G.W.), and the Bristol Royal Infirmary, Bristol (A.J.P.) - all in the United Kingdom.
Portal AJ; From the Institute for Liver and Digestive Health (L.C., N.B.S., A.O.), the Comprehensive Clinical Trials Unit (N.F.), and the Division of Medicine, University College London (D.W.G.), Barts and the London School of Medicine and Dentistry, Queen Mary University of London (Y.K.), London, the Glasgow Royal Infirmary and the University of Glagow, Glasgow (E.F.), the National Institute for Health Research Nottingham Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Nottingham (S.D.R.), the Mid and South Essex NHS Foundation Trust and the Basildon and Thurrock University Hospitals NHS Foundation Trust, Basildon (G.W.), and the Bristol Royal Infirmary, Bristol (A.J.P.) - all in the United Kingdom.
Becares Salles N; From the Institute for Liver and Digestive Health (L.C., N.B.S., A.O.), the Comprehensive Clinical Trials Unit (N.F.), and the Division of Medicine, University College London (D.W.G.), Barts and the London School of Medicine and Dentistry, Queen Mary University of London (Y.K.), London, the Glasgow Royal Infirmary and the University of Glagow, Glasgow (E.F.), the National Institute for Health Research Nottingham Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Nottingham (S.D.R.), the Mid and South Essex NHS Foundation Trust and the Basildon and Thurrock University Hospitals NHS Foundation Trust, Basildon (G.W.), and the Bristol Royal Infirmary, Bristol (A.J.P.) - all in the United Kingdom.
Gilroy DW; From the Institute for Liver and Digestive Health (L.C., N.B.S., A.O.), the Comprehensive Clinical Trials Unit (N.F.), and the Division of Medicine, University College London (D.W.G.), Barts and the London School of Medicine and Dentistry, Queen Mary University of London (Y.K.), London, the Glasgow Royal Infirmary and the University of Glagow, Glasgow (E.F.), the National Institute for Health Research Nottingham Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Nottingham (S.D.R.), the Mid and South Essex NHS Foundation Trust and the Basildon and Thurrock University Hospitals NHS Foundation Trust, Basildon (G.W.), and the Bristol Royal Infirmary, Bristol (A.J.P.) - all in the United Kingdom.
O'Brien A; From the Institute for Liver and Digestive Health (L.C., N.B.S., A.O.), the Comprehensive Clinical Trials Unit (N.F.), and the Division of Medicine, University College London (D.W.G.), Barts and the London School of Medicine and Dentistry, Queen Mary University of London (Y.K.), London, the Glasgow Royal Infirmary and the University of Glagow, Glasgow (E.F.), the National Institute for Health Research Nottingham Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Centre, Nottingham (S.D.R.), the Mid and South Essex NHS Foundation Trust and the Basildon and Thurrock University Hospitals NHS Foundation Trust, Basildon (G.W.), and the Bristol Royal Infirmary, Bristol (A.J.P.) - all in the United Kingdom.
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Corporate Authors :
ATTIRE Trial Investigators
Źródło :
The New England journal of medicine [N Engl J Med] 2021 Mar 04; Vol. 384 (9), pp. 808-817.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Serum Albumin*
Albumins/*therapeutic use
Liver Cirrhosis/*therapy
Adult ; Albumins/administration & dosage ; Albumins/adverse effects ; Ascites/etiology ; Ascites/therapy ; Female ; Hospitalization ; Humans ; Infusions, Intravenous ; Liver Cirrhosis/blood ; Liver Cirrhosis/complications ; Liver Cirrhosis/mortality ; Liver Cirrhosis, Alcoholic/blood ; Liver Cirrhosis, Alcoholic/therapy ; Male ; Middle Aged ; Pulmonary Edema/etiology ; Treatment Failure
Czasopismo naukowe
Tytuł :
Effect of genotype and some shell quality traits on lysozyme content and activity in the albumen of eggs from hens under the biodiversity conservation program.
Autorzy :
Lewko L; National Research Institute of Animal Production, Experimental Station Kołuda Wielka, Waterfowl Genetic Resources Station in Dworzyska, 62-035 Kórnik, Poland. Electronic address: .
Krawczyk J; National Research Institute of Animal Production, Department of Poultry Breeding, 32-083 Balice, Poland.
Calik J; National Research Institute of Animal Production, Department of Poultry Breeding, 32-083 Balice, Poland.
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Źródło :
Poultry science [Poult Sci] 2021 Mar; Vol. 100 (3), pp. 100863. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Albumins*/genetics
Albumins*/metabolism
Chickens*/classification
Chickens*/genetics
Egg Shell*/physiology
Muramidase*/genetics
Muramidase*/metabolism
Ovum*/chemistry
Ovum*/enzymology
Animals ; Biodiversity ; Female ; Genotype ; Poland
Czasopismo naukowe
Tytuł :
Epitope mapping of the major allergen 2S albumin from pine nut.
Autorzy :
Crespo JF; Department of Allergy, Research Institute Hospital 12 de Octubre, Avenida de Córdoba s/n, 28041 Madrid, Spain.
Bueno C; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Madrid, Spain.
Villalba M; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Madrid, Spain.
Monaci L; Institute of Sciences of Food Production, CNR-ISPA, 70126 Bari, Italy.
Cuadrado C; Department of Food Technology, National Institute of Agricultural, Food Research, and Technology (INIA), Ctra. La Coruña Km. 7.5, 28040 Madrid, Spain.
Novak N; Department of Dermatology and Allergy, University Hospital Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Cabanillas B; Department of Allergy, Research Institute Hospital 12 de Octubre, Avenida de Córdoba s/n, 28041 Madrid, Spain. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Mar 01; Vol. 339, pp. 127895. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
2S Albumins, Plant/*chemistry
Allergens/*chemistry
Epitope Mapping/*methods
Epitopes/*chemistry
Pinus/*metabolism
2S Albumins, Plant/immunology ; 2S Albumins, Plant/metabolism ; Adolescent ; Adult ; Allergens/immunology ; Amino Acid Sequence ; Arachis/immunology ; Arachis/metabolism ; Epitopes/immunology ; Female ; Humans ; Immunoglobulin E/blood ; Immunoglobulin E/immunology ; Male ; Nut Hypersensitivity/immunology ; Nut Hypersensitivity/pathology ; Nuts/immunology ; Nuts/metabolism ; Peptide Library ; Pinus/immunology
Czasopismo naukowe
Tytuł :
Terlipressin and Intravenous Albumin in Advanced Cirrhosis - Friend and Foe.
Autorzy :
Garcia-Tsao G; From the Section of Digestive Diseases, Yale School of Medicine, New Haven, and the Section of Digestive Diseases, Veterans Affairs Connecticut Healthcare System, West Haven - both in Connecticut.
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Źródło :
The New England journal of medicine [N Engl J Med] 2021 Mar 04; Vol. 384 (9), pp. 869-871.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Albumins*
Liver Cirrhosis*/complications
Liver Cirrhosis*/drug therapy
Humans ; Terlipressin
Opinia redakcyjna
Tytuł :
Elevated Plasma Concentrations of Syndecan-1 Do Not Correlate With Increased Capillary Leakage of 20% Albumin.
Autorzy :
Hahn RG; From the Research Unit, Södertälje Hospital, Södertälje, Sweden.; Karolinska Institutet at Danderyds Hospital (KIDS).
Zdolsek M; Department Biomedical and Clinical Sciences (BKV), Linköping University, Linköping, Sweden.
Krizhanovskii C; From the Research Unit, Södertälje Hospital, Södertälje, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet.
Ntika S; From the Research Unit, Södertälje Hospital, Södertälje, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet.
Zdolsek J; Department Biomedical and Clinical Sciences (BKV), Linköping University, Linköping, Sweden.
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Źródło :
Anesthesia and analgesia [Anesth Analg] 2021 Mar 01; Vol. 132 (3), pp. 856-865.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Capillary Permeability*
Fluid Therapy*/adverse effects
Albumins/*administration & dosage
Burns/*therapy
Endothelial Cells/*metabolism
Glycocalyx/*metabolism
Syndecan-1/*blood
Adult ; Aged ; Albumins/adverse effects ; Biomarkers/blood ; Burns/blood ; Burns/physiopathology ; Female ; Heparitin Sulfate/blood ; Humans ; Infusions, Intravenous ; Male ; Middle Aged ; Prospective Studies ; Sweden ; Time Factors ; Up-Regulation
Czasopismo naukowe
Tytuł :
A phase II trial of dose-reduced nab-paclitaxel for patients with previously treated, advanced or recurrent gastric cancer (OGSG 1302).
Autorzy :
Tamura S; Department of Surgery, Yao Municipal Hospital, 1-3-1, Ryuge, Yao, Osaka, 581-0069, Japan. .
Taniguchi H; Department of Gastroenterological Surgery, Osaka Saiseikai Senri Hospital, Suita, Osaka, Japan.
Nishikawa K; Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Imamura H; Department of Surgery, Toyonaka Municipal Hospital, Toyonaka, Osaka, Japan.
Fujita J; Department of Surgery, Sakai City Medical Center, Sakai, Osaka, Japan.
Takeno A; Department of Surgery, Kansai Rosai Hospital, Amagasaki, Hyogo, Japan.
Matsuyama J; Department of Gastroenterological Surgery, Higashiosaka City Medical Center, Higashiosaka, Osaka, Japan.
Kimura Y; Department of Surgery, Kindai University Hospital, Sayama, Osaka, Japan.
Kawada J; Department of Surgery, Yao Municipal Hospital, 1-3-1, Ryuge, Yao, Osaka, 581-0069, Japan.
Hirao M; Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Hirota M; Department of Surgery, Toyonaka Municipal Hospital, Toyonaka, Osaka, Japan.
Fujitani K; Department of Surgery, Osaka General Medical Center, Osaka, Japan.
Kurokawa Y; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Sakai D; Department of Frontier Science for Cancer and Chemotherapy, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Kawakami H; Department of Medical Oncology, Faculty of Medicine, Kindai University, Sayama, Osaka, Japan.
Shimokawa T; Clinical Study Support Center, Wakayama Medical University, Wakayama, Japan.
Satoh T; Department of Frontier Science for Cancer and Chemotherapy, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
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Źródło :
International journal of clinical oncology [Int J Clin Oncol] 2020 Dec; Vol. 25 (12), pp. 2035-2043. Date of Electronic Publication: 2020 Sep 14.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Multicenter Study
MeSH Terms :
Adenocarcinoma/*drug therapy
Albumins/*administration & dosage
Albumins/*adverse effects
Antineoplastic Agents, Phytogenic/*administration & dosage
Paclitaxel/*administration & dosage
Paclitaxel/*adverse effects
Stomach Neoplasms/*drug therapy
Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Aged ; Aged, 80 and over ; Albumins/therapeutic use ; Anorexia/chemically induced ; Anorexia/epidemiology ; Antineoplastic Agents, Phytogenic/adverse effects ; Antineoplastic Agents, Phytogenic/therapeutic use ; Dose-Response Relationship, Drug ; Fatigue/chemically induced ; Fatigue/epidemiology ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Neutropenia/chemically induced ; Neutropenia/epidemiology ; Paclitaxel/therapeutic use ; Peripheral Nervous System Diseases/chemically induced ; Peripheral Nervous System Diseases/epidemiology ; Stomach Neoplasms/mortality ; Stomach Neoplasms/pathology ; Treatment Outcome
Czasopismo naukowe
Tytuł :
The forgotten 2S albumin proteins: Importance, structure, and biotechnological application in agriculture and human health.
Autorzy :
Souza PFN; Laboratory of Plant Defense Proteins, Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Dec 01; Vol. 164, pp. 4638-4649. Date of Electronic Publication: 2020 Sep 13.
Typ publikacji :
Comparative Study; Journal Article; Review
MeSH Terms :
2S Albumins, Plant*/chemistry
2S Albumins, Plant*/pharmacology
2S Albumins, Plant*/physiology
2S Albumins, Plant*/therapeutic use
Agrochemicals ; Allergens/immunology ; Amino Acid Sequence ; Anti-Infective Agents/isolation & purification ; Anti-Infective Agents/pharmacology ; Anti-Infective Agents/therapeutic use ; Drug Evaluation, Preclinical ; Humans ; Models, Molecular ; Molecular Structure ; Protein Conformation ; Seeds/chemistry ; Sequence Alignment ; Sequence Homology, Amino Acid ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Development of an updated assay for prekallikrein activator in albumin and immunoglobulin therapeutics.
Autorzy :
Roberts G; Biotherapeutics Division, National Institute for Biological Standards and Control, South Mimms, UK.
Fox B; Biotherapeutics Division, National Institute for Biological Standards and Control, South Mimms, UK.
Longstaff C; Biotherapeutics Division, National Institute for Biological Standards and Control, South Mimms, UK.
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Źródło :
Vox sanguinis [Vox Sang] 2021 Jan; Vol. 116 (1), pp. 99-105. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article
MeSH Terms :
Albumins*
Immunoglobulins*
Factor XIIa/*analysis
Factor XIIa/metabolism ; Humans ; Prekallikrein/metabolism ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Clinical Pharmacist-Led Impact on Inappropriate Albumin Utilization and Associated Costs in General Ward Patients.
Autorzy :
Buckley MS; Banner-University Medical Center Phoenix, Phoenix, AZ, USA.
Agarwal SK; Banner-University Medical Center Phoenix, Phoenix, AZ, USA.
Lansburg JM; Banner-University Medical Center Phoenix, Phoenix, AZ, USA.
Kopp BJ; Banner-University Medical Center Tucson, Tucson, AZ, USA.
Erstad BL; University of Arizona, Tucson, AZ, USA.
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Źródło :
The Annals of pharmacotherapy [Ann Pharmacother] 2021 Jan; Vol. 55 (1), pp. 44-51. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Journal Article
MeSH Terms :
Albumins/*economics
Drug Utilization/*economics
Inappropriate Prescribing/*economics
Pharmacy Service, Hospital/*standards
Adult ; Albumins/therapeutic use ; Cost Savings ; Drug Costs ; Drug Utilization/statistics & numerical data ; Female ; Hospitalization/economics ; Hospitals, Teaching/economics ; Hospitals, Teaching/organization & administration ; Humans ; Inappropriate Prescribing/statistics & numerical data ; Male ; Middle Aged ; Patient Admission ; Pharmacists/standards ; Pharmacy Service, Hospital/statistics & numerical data ; Retrospective Studies
Czasopismo naukowe
Tytuł :
CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study.
Autorzy :
O'Hara MH; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
O'Reilly EM; Department of Medical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Varadhachary G; Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, MD Anderson Cancer Center, Houston, TX, USA.
Wolff RA; Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, MD Anderson Cancer Center, Houston, TX, USA.
Wainberg ZA; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Ko AH; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Fisher G; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Rahma O; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Lyman JP; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Cabanski CR; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Mick R; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Gherardini PF; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Kitch LJ; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Xu J; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Samuel T; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Karakunnel J; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Fairchild J; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Bucktrout S; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
LaVallee TM; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Selinsky C; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Till JE; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Carpenter EL; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Alanio C; Parker Institute for Cancer Immunotherapy at the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Byrne KT; Parker Institute for Cancer Immunotherapy at the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Chen RO; Personalis, Menlo Park, CA, USA.
Trifan OC; Apexigen, San Carlos, CA, USA.
Dugan U; Bristol Myers Squibb, New York, NY, USA.
Horak C; Bristol Myers Squibb, New York, NY, USA.
Hubbard-Lucey VM; Cancer Research Institute, New York, NY, USA.
Wherry EJ; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Parker Institute for Cancer Immunotherapy at the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Ibrahim R; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Vonderheide RH; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Parker Institute for Cancer Immunotherapy at the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: .
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Źródło :
The Lancet. Oncology [Lancet Oncol] 2021 Jan; Vol. 22 (1), pp. 118-131.
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenocarcinoma/*drug therapy
Albumins/*administration & dosage
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
CD40 Antigens/*antagonists & inhibitors
Deoxycytidine/*analogs & derivatives
Nivolumab/*administration & dosage
Paclitaxel/*administration & dosage
Pancreatic Neoplasms/*drug therapy
Adenocarcinoma/immunology ; Adenocarcinoma/secondary ; Aged ; Albumins/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; CD40 Antigens/immunology ; Deoxycytidine/administration & dosage ; Deoxycytidine/adverse effects ; Female ; Humans ; Male ; Middle Aged ; Nivolumab/adverse effects ; Paclitaxel/adverse effects ; Pancreatic Neoplasms/immunology ; Pancreatic Neoplasms/pathology ; Time Factors ; Treatment Outcome ; United States
Czasopismo naukowe
Tytuł :
Comparison of nab-paclitaxel plus gemcitabine in elderly versus younger patients with metastatic pancreatic cancer: Analysis of a multicentre, prospective, non-interventional study.
Autorzy :
Prager GW; Medical University of Vienna, Department of Oncology, Währinger Gürtel 18-20, 1090, Vienna, Austria. Electronic address: .
Oehler L; Sankt Josef Krankenhaus, Internal Medicine 2, Auhofstraße 189, 1130, Vienna, Wien, Austria. Electronic address: .
Gerger A; Medical University of Graz, Clinical Institute of Oncology, Auenbruggerplatz 15, 8036, Graz, Austria. Electronic address: .
Mlineritsch B; Universitätsklinik Salzburg, University Clinic for Internal Medicine III, Müllner Haupstraße 48, 5020, Salzburg, Austria. Electronic address: .
Andel J; Pyhrn-Eisenwurzen Klinikum, Internal Medicine II, Sierningerstraße 170, 4400, Steyr, Austria. Electronic address: .
Petzer A; Ordensklinikum Linz BHS - EKH, Internal Medicine I, Medical Oncology and Hematology, Seilerstätte 4, 4010, Linz Austria. Electronic address: .
Wilthoner K; Landeskrankenhaus Vöcklabruck, Vöcklabruck, Internal Medicine, Hemato-Oncology, Dr. Wilhelm-Bock-Straße 1, 4840 Vöcklabruck, Austria. Electronic address: .
Sliwa T; Hanuschkrankenhaus, Medicine III for Hematology and Oncology, Heinrich-Collin-Straße 30, 1140, Wien, Vienna, Austria. Electronic address: .
Pichler P; Universitätsklinikum St. Pölten, Internal Medicine I, Dunant-Platz 1, 3100, Sankt Pölten, Austria. Electronic address: .
Winder T; Landeskrankenhaus Feldkirch, Internal Medicine II, Carinagasse 47, 6807, Feldkirch, Austria. Electronic address: .
Heibl S; Klinikum Wels-Grieskirchen, Internal Medicine IV, Grieskirchner Straße 42, 4600, Wels, Austria. Electronic address: .
Gruenberger B; Landesklinikum Wiener Neustadt, Internal Medicine for Hematology and Internal Oncology, Corvinusring 2-5, 2700, Wiener Neustadt, Austria. Electronic address: .
Laengle F; Landesklinikum Wiener Neustadt, Department of Surgery, Corvinusring 2-5, 2700, Wiener Neustadt, Austria. Electronic address: .
Hubmann E; Krankenhaus der Barmherzigen Brüder, Internal Medicine, Marschallgasse 12, 8020, Graz, Austria. Electronic address: .
Korger M; Krankenhaus der Barmherzigen Brüder, Internal Medicine II, Johannes von Gott-Platz 1, 7000, Eisenstadt, Austria. Electronic address: .
Pecherstorfer M; Karl Landsteiner University of Health Sciences, Department of Internal Medicine, University Hospital, 3500, Krems an der Donau, Austria. Electronic address: .
Djanani A; Medical University of Innsbruck, Institute of Gastroenterology, Internal Medicine I, Institute of Gastroenterology, Anichstraße 35, 6020, Innsbruck, Austria. Electronic address: .
Neumann HJ; Krankenhaus der Elisabethinen, Internal Medicine, Völkermarkter Straße 15-19, 9020, Klagenfurt, Austria. Electronic address: .
Philipp-Abbrederis K; Medical University of Innsbruck, Institute of Hematology and Oncology, Internal Medicine V, Institute of Hematology and Oncology, Anichstraße 35, 6020, Innsbruck, Austria. Electronic address: .
Wöll E; Krankenhaus Zams, Internal Medicine, Sanatoriumstraße 43, 6511, Zams, Austria. Electronic address: .
Trondl R; Celgene Austria GmbH, EuroPlaza Building E, Technologiestraße 10, 1120, Vienna, Austria. Electronic address: .
Arnold-Schrauf C; Celgene Austria GmbH, EuroPlaza Building E, Technologiestraße 10, 1120, Vienna, Austria. Electronic address: .
Eisterer W; Klinikum Klagenfurt Am Wörthersee, Internal Medicine and Oncology, Feschnigstraße 11, 9020, Klagenfurt, Austria. Electronic address: .
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Źródło :
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2021 Jan; Vol. 143, pp. 101-112. Date of Electronic Publication: 2020 Dec 06.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Albumins/*therapeutic use
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Deoxycytidine/*analogs & derivatives
Paclitaxel/*therapeutic use
Pancreatic Neoplasms/*drug therapy
Aged ; Albumins/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Deoxycytidine/pharmacology ; Deoxycytidine/therapeutic use ; Female ; Humans ; Male ; Paclitaxel/pharmacology ; Pancreatic Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Survey of egg quality in commercially available table eggs.
Autorzy :
Hisasaga C; Department of Animal Sciences and Agricultural Education, California State University Fresno, Fresno, CA 93740.
Griffin SE; Department of Food Science and Nutrition, California State University Fresno, Fresno, CA 93740.
Tarrant KJ; Department of Animal Sciences and Agricultural Education, California State University Fresno, Fresno, CA 93740. Electronic address: .
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Źródło :
Poultry science [Poult Sci] 2020 Dec; Vol. 99 (12), pp. 7202-7206. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article
MeSH Terms :
Albumins*/analysis
Chickens*
Eggs*/analysis
Eggs*/standards
Food Quality*
Animals ; Egg Shell/chemistry ; Egg Yolk/chemistry
Czasopismo naukowe
Tytuł :
Phase II multi-institutional prospective trial of nab-paclitaxel as second-line chemotherapy for advanced gastric cancer refractory to fluoropyrimidine with modified dose reduction criteria (CCOG1303).
Autorzy :
Kobayashi D; Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. .
Mochizuki Y; Department of Surgery, Komaki City Hospital, Komaki, Japan.
Torii K; Department of Surgery, Meitetsu Hospital, Nagoya, Japan.
Takeda S; Department of Surgery, National Hospital Organization Nagoya Medical Center, Nagoya, Japan.
Kawase Y; Department of Surgery, Tosei General Hospital, Seto, Japan.
Ishigure K; Department of Surgery, Konan Kosei Hospital, Konan, Japan.
Teramoto H; Department of Surgery, Yokkaichi Municipal Hospital, Yokkaichi, Japan.
Ando M; Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan.
Kodera Y; Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
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Źródło :
International journal of clinical oncology [Int J Clin Oncol] 2020 Oct; Vol. 25 (10), pp. 1793-1799. Date of Electronic Publication: 2020 Jun 21.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study
MeSH Terms :
Albumins/*administration & dosage
Albumins/*therapeutic use
Paclitaxel/*administration & dosage
Paclitaxel/*therapeutic use
Stomach Neoplasms/*drug therapy
Adult ; Aged ; Aged, 80 and over ; Albumins/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Disease-Free Survival ; Dose-Response Relationship, Drug ; Female ; Humans ; Male ; Middle Aged ; Neutropenia/chemically induced ; Paclitaxel/adverse effects ; Prospective Studies ; Stomach Neoplasms/mortality ; Stomach Neoplasms/pathology ; Treatment Failure
Czasopismo naukowe
Tytuł :
Clinical characteristics and blood/serum bound prognostic biomarkers in advanced pancreatic cancer treated with gemcitabine and nab-paclitaxel.
Autorzy :
Blomstrand H; Department of Clinical Pathology and Department of Biomedical and Clinical Sciences, Linköping University, 58183, Linköping, Sweden.
Green H; Division of Drug Research, Department of Medical Health Sciences, Linköping University, 58183, Linköping, Sweden.; Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, 58758, Linköping, Sweden.
Fredrikson M; Forum Östergötland, Linköping University, 58185, Linköping, Sweden.
Gränsmark E; Department of Oncology, Kalmar County Hospital, 392 44, Kalmar, Sweden.
Björnsson B; Department of Surgery and Department of Biomedical and Clinical Sciences, Linköping University, 58183, Linköping, Sweden.
Elander NO; Department of Oncology and Department of Biomedical and Clinical Sciences, Linköping University, 58183, Linköping, Sweden. .
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Źródło :
BMC cancer [BMC Cancer] 2020 Oct 02; Vol. 20 (1), pp. 950. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article
MeSH Terms :
Albumins/*therapeutic use
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Biomarkers, Tumor/*metabolism
Deoxycytidine/*analogs & derivatives
Paclitaxel/*therapeutic use
Pancreatic Neoplasms/*drug therapy
Aged ; Albumins/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Deoxycytidine/pharmacology ; Deoxycytidine/therapeutic use ; Female ; Humans ; Male ; Paclitaxel/pharmacology ; Prognosis ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Effect of heat treatment on the conformational stability of intact and cleaved forms ofthe peanut allergen Ara h 6 in relation to its IgE-binding potency.
Autorzy :
de Jongh HHJ; ProtIn Consultancy, Rozenstraat 19E, 3702 VL Zeist, The Netherlands.
de Jong GAH; TNO, Utrechtseweg 48, 3704 HE Zeist, The Netherlands.
Apostolovic D; Clinical Immunology and Allergy Unit, Department of Medicine Solna, Karolinska Institutet, Solnavägen 1, 171 77 Solna, Sweden.
Taylor SL; Food Allergy Research and Resource Program, Department of Food Science & Technology, University of Nebraska, 279 Food Innovation Center, Lincoln, NE 68588-6207, USA.
Baumert JL; Food Allergy Research and Resource Program, Department of Food Science & Technology, University of Nebraska, 279 Food Innovation Center, Lincoln, NE 68588-6207, USA.
Koppelman SJ; Food Allergy Research and Resource Program, Department of Food Science & Technology, University of Nebraska, 279 Food Innovation Center, Lincoln, NE 68588-6207, USA. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2020 Oct 01; Vol. 326, pp. 127027. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
2S Albumins, Plant/*chemistry
Allergens/*chemistry
Antigens, Plant/*chemistry
Arachis/*chemistry
Immunoglobulin E/*immunology
2S Albumins, Plant/immunology ; Allergens/immunology ; Antigens, Plant/immunology ; Hot Temperature ; Protein Conformation ; Time Factors
Czasopismo naukowe
Tytuł :
Neutrophil count to albumin ratio as a new predictor of mortality in patients with COVID-19 ınfection.
Autorzy :
Varim C; Associate Professor, Department of Internal Medicine, Sakarya University Medicine Faculty, Sakarya, Turkey.
Yaylaci S; Associate Professor, Department of Internal Medicine, Sakarya University Medicine Faculty, Sakarya, Turkey.
Demirci T; Associate Professor, Department of Internal Medicine, Sakarya University Medicine Faculty, Sakarya, Turkey.
Kaya T; Associate Professor, Department of Internal Medicine, Sakarya University Medicine Faculty, Sakarya, Turkey.
Nalbant A; Associate Professor, Department of Internal Medicine, Sakarya University Medicine Faculty, Sakarya, Turkey.
Dheir H; Associate Professor, Department of Internal Medicine Division of Nephrology, Sakarya University Medicine Faculty, Sakarya, Turkey.
Senocak D; Associate Professor, Department of Internal Medicine, Sakarya University Medicine Faculty, Sakarya, Turkey.
Kurt R; Medical Doctor, Department of Internal Medicine, Sakarya University Medicine Faculty, Sakarya, Turkey.
Cengiz H; Hasret Cengiz, Medical Doctor, Department of Endocrinology, Sakarya University Medicine Faculty, Sakarya, Turkey.
Karacaer C; Hasret Cengiz, Medical Doctor, Department of Endocrinology, Sakarya University Medicine Faculty, Sakarya, Turkey.
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Źródło :
Revista da Associacao Medica Brasileira (1992) [Rev Assoc Med Bras (1992)] 2020 Sep 21; Vol. 66Suppl 2 (Suppl 2), pp. 77-81. Date of Electronic Publication: 2020 Sep 21 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Albumins*
Neutrophils*
Pandemics*
Coronavirus Infections/*epidemiology
Pneumonia, Viral/*epidemiology
Aged ; Aged, 80 and over ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/blood ; Coronavirus Infections/diagnosis ; Female ; Humans ; Male ; Middle Aged ; Pneumonia, Viral/blood ; Pneumonia, Viral/diagnosis ; ROC Curve ; Retrospective Studies ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
Gemcitabine plus nab-paclitaxel until progression or alternating with FOLFIRI.3, as first-line treatment for patients with metastatic pancreatic adenocarcinoma: The Federation Francophone de Cancérologie Digestive-PRODIGE 37 randomised phase II study (FIRGEMAX).
Autorzy :
Rinaldi Y; Department of Hepato-gastroenterology, European Hospital, Marseille, France.
Pointet AL; Department of Hepato-gastroenterology, Georges Pompidou European Hospital, Paris, France.
Khemissa Akouz F; Department of Hepato-gastroenterology, Saint Jean Hospital, Perpignan, France.
Le Malicot K; Biostatistics Department, Francophone Federation of Digestive Cancerology, EPICAD INSERM LNC-UMR 1231, University of Burgundy and Franche Comté, Dijon, France.
Wahiba B; Department of Hepato-gastroenterology, European Hospital, Marseille, France.
Louafi S; Department of Oncology, Sud Francilien Hospital Center, Corbeil-Essonnes, France.
Gratet A; Oncology and Hematology ONCOSUD Unit, Clinic Pasteur, Toulouse, France.
Miglianico L; Department of Radiotherapy, Private Hospital Center, Saint-Grégoire, France.
Laharie H; Department of Oncology and Radiotherapy, Clinic Tivoli, Bordeaux, France.
Bouhier Leporrier K; Department of Hepato-gastroenterology, University Hospital, Caen, France.
Thirot Bidault A; Department of Hepato-gastroenterology, Private Hospital, Antony, France.
Texereau P; Department of Hepato-gastroenterology, Layne Hospital, Mont-De-Marsan, France.
Coriat R; Department of Hepato-gastroenterology, Cochin Hospital, APHP, Paris, France.
Terrebonne E; Department of Hepato-gastroenterology, Haut Lévêque Hospital, Pessac, France.
Gouttebel MC; Department of Oncology, Drôme Nord Hospital, Romans Sur Isère, France.
Malka D; Department of Hepato-gastroenterology, Gustave Roussy Cancer Campus, Villejuif, France.
Bachet JB; Department of Hepato-gastroenterology, Pitié-Salpêtrière Hospital, Paris, France.
Lepage C; Department of Hepato-gastroenterology, University Hospital of Dijon, EPICAD INSERM LNC-UMR 1231, University of Burgundy and Franche Comté, Dijon, France.
Taieb J; Department of Hepato-gastroenterology, Sorbonne Paris City, Paris Descartes University, Georges Pompidou European Hospital, Paris, France. Electronic address: .
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Corporate Authors :
PRODIGE 37 Investigators/Collaborators
Źródło :
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2020 Sep; Vol. 136, pp. 25-34. Date of Electronic Publication: 2020 Jul 02.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenocarcinoma/*drug therapy
Albumins/*administration & dosage
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Deoxycytidine/*analogs & derivatives
Paclitaxel/*administration & dosage
Pancreatic Neoplasms/*drug therapy
Adenocarcinoma/pathology ; Adult ; Aged ; Albumins/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Camptothecin/administration & dosage ; Camptothecin/adverse effects ; Camptothecin/analogs & derivatives ; Deoxycytidine/administration & dosage ; Deoxycytidine/adverse effects ; Disease Progression ; Drug Substitution ; Female ; Fluorouracil/administration & dosage ; Fluorouracil/adverse effects ; France ; Humans ; Irinotecan/administration & dosage ; Irinotecan/adverse effects ; Leucovorin/administration & dosage ; Leucovorin/adverse effects ; Male ; Middle Aged ; Neoadjuvant Therapy ; Neoplasm Metastasis ; Paclitaxel/adverse effects ; Pancreatic Neoplasms/pathology ; Progression-Free Survival ; Treatment Outcome
SCR Protocol :
IFL protocol
Czasopismo naukowe
Tytuł :
First-line gemcitabine plus nab-paclitaxel for elderly patients with metastatic pancreatic cancer: Crossing the frontier of age?
Autorzy :
Vivaldi C; Unit of Medical Oncology, Azienda Ospedaliero-Universitaria Pisana, Via Roma 67, Pisa, 56126, Italy; Department of Translational Research and New Surgical and Medical Technologies, University of Pisa, Via Savi 6, Pisa, 56126, Italy.
Salani F; Unit of Medical Oncology, Azienda Ospedaliero-Universitaria Pisana, Via Roma 67, Pisa, 56126, Italy.
Rovesti G; Department of Oncology and Hematology, Division of Oncology, University of Modena and Reggio Emilia, Via del Pozzo 71, Modena, 41100, Italy.
Pecora I; Unit of Medical Oncology, Azienda Ospedaliero-Universitaria Pisana, Via Roma 67, Pisa, 56126, Italy.
Catanese S; Unit of Medical Oncology, Azienda Ospedaliero-Universitaria Pisana, Via Roma 67, Pisa, 56126, Italy.
Casadei-Gardini A; Department of Medical Oncology, Istituto Scientifico Romagnolo per Lo Studio e La Cura Dei Tumori (IRST) IRCCS, Via P. Maroncelli N. 40, Meldola, 47014, Italy.
Massa V; Unit of Medical Oncology, Azienda Ospedaliero-Universitaria Pisana, Via Roma 67, Pisa, 56126, Italy.
Bernardini L; Unit of Medical Oncology, Azienda Ospedaliero-Universitaria Pisana, Via Roma 67, Pisa, 56126, Italy.
Riggi L; Department of Oncology and Hematology, Division of Oncology, University of Modena and Reggio Emilia, Via del Pozzo 71, Modena, 41100, Italy.
Andrikou K; Department of Oncology and Hematology, Division of Oncology, University of Modena and Reggio Emilia, Via del Pozzo 71, Modena, 41100, Italy.
Rapposelli GI; Department of Medical Oncology, Istituto Scientifico Romagnolo per Lo Studio e La Cura Dei Tumori (IRST) IRCCS, Via P. Maroncelli N. 40, Meldola, 47014, Italy.
Formica V; Medical Oncology Unit, Tor Vergata University, Viale Oxford 81, Rome, 00133, Italy.
Lencioni M; Unit of Medical Oncology, Azienda Ospedaliero-Universitaria Pisana, Via Roma 67, Pisa, 56126, Italy.
Falcone A; Unit of Medical Oncology, Azienda Ospedaliero-Universitaria Pisana, Via Roma 67, Pisa, 56126, Italy; Department of Translational Research and New Surgical and Medical Technologies, University of Pisa, Via Savi 6, Pisa, 56126, Italy.
Vasile E; Unit of Medical Oncology, Azienda Ospedaliero-Universitaria Pisana, Via Roma 67, Pisa, 56126, Italy.
Fornaro L; Unit of Medical Oncology, Azienda Ospedaliero-Universitaria Pisana, Via Roma 67, Pisa, 56126, Italy. Electronic address: .
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Źródło :
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2020 Sep; Vol. 137, pp. 108-116. Date of Electronic Publication: 2020 Aug 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Albumins/*therapeutic use
Antimetabolites, Antineoplastic/*therapeutic use
Deoxycytidine/*analogs & derivatives
Paclitaxel/*therapeutic use
Pancreatic Neoplasms/*drug therapy
Aged ; Aged, 80 and over ; Albumins/pharmacology ; Antimetabolites, Antineoplastic/pharmacology ; Deoxycytidine/pharmacology ; Deoxycytidine/therapeutic use ; Female ; Humans ; Male ; Neoplasm Metastasis ; Paclitaxel/pharmacology ; Pancreatic Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Phase II results from a phase I/II study to assess the safety and efficacy of weekly nab-paclitaxel in paediatric patients with recurrent or refractory solid tumours: A collaboration with the European Innovative Therapies for Children with Cancer Network.
Autorzy :
Amoroso L; Oncology Unit, IRCCS Istituto Giannina Gaslini, Genova, Italy. Electronic address: .
Castel V; Pediatric Hematology/Oncology Unit, University Hospital La Fe, Valencia, Spain.
Bisogno G; Hematology/Oncology Division, Department of Women's and Children's Health, University of Padova, Padova, Italy.
Casanova M; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Marquez-Vega C; Hospital Universitario Virgen del Rocío, Seville, Spain.
Chisholm JC; Royal Marsden Hospital, Sutton, UK.
Doz F; Institut Curie and Paris Descartes University, Paris, France.
Moreno L; Hospital Infantil Universitario Niño Jesús, Madrid, Spain; Hospital Universitario Vall D'Hebron, Barcelona, Spain.
Ruggiero A; Gemelli Hospital, Catholic University of Rome, Rome, Italy.
Gerber NU; University Children's Hospital, Zurich, Switzerland.
Fagioli F; Pediatric Oncology Department, Regina Margherita Children's Hospital, AOU Città della Salute e Della Scienza di Torino, Turin, Italy; Department of Public Health and Paediatric Sciences, University of Torino, Turin, Italy.
Hingorani P; Department of Pediatrics, MD Anderson Cancer Center, Houston, TX, USA.
Melcón SG; Hospital Universitario Vall D'Hebron, Barcelona, Spain.
Slepetis R; Bristol-Myers Squibb, Princeton, NJ, USA.
Chen N; Bristol-Myers Squibb, Princeton, NJ, USA.
le Bruchec Y; Celgene International, A Bristol-Myers Squibb Company, Boudry, Switzerland.
Simcock M; Celgene International, A Bristol-Myers Squibb Company, Boudry, Switzerland.
Vassal G; Gustave Roussy, Villejuif, France.
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Źródło :
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2020 Aug; Vol. 135, pp. 89-97. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Albumins/*administration & dosage
Antineoplastic Agents, Phytogenic/*administration & dosage
Bone Neoplasms/*drug therapy
Neuroblastoma/*drug therapy
Paclitaxel/*administration & dosage
Rhabdomyosarcoma/*drug therapy
Sarcoma, Ewing/*drug therapy
Adolescent ; Age Factors ; Albumins/adverse effects ; Albumins/pharmacokinetics ; Antineoplastic Agents, Phytogenic/adverse effects ; Antineoplastic Agents, Phytogenic/pharmacokinetics ; Bone Neoplasms/mortality ; Bone Neoplasms/pathology ; Child ; Child, Preschool ; Drug Administration Schedule ; Europe ; Female ; Humans ; Infant ; Male ; Neuroblastoma/mortality ; Neuroblastoma/pathology ; Paclitaxel/adverse effects ; Paclitaxel/pharmacokinetics ; Progression-Free Survival ; Rhabdomyosarcoma/mortality ; Rhabdomyosarcoma/pathology ; Sarcoma, Ewing/mortality ; Sarcoma, Ewing/pathology ; Time Factors ; Tissue Distribution ; Young Adult
Czasopismo naukowe
Tytuł :
EFFECT: a randomized phase II study of efficacy and impact on function of two doses of nab-paclitaxel as first-line treatment in older women with advanced breast cancer.
Autorzy :
Biganzoli L; 'Sandro Pitigliani' Department of Medical Oncology, Hospital of Prato, ASL Toscana Centro, Prato, Italy. .
Cinieri S; Department of Medical Oncology, Perrino Hospital, ASL Brindisi, Brindisi, Italy.
Berardi R; Department of Medical Oncology, Ospedali Riuniti di Ancona, Università Politecnica delle Marche, Ancona, Italy.
Pedersini R; Breast Oncology Unit, Hospital Civili di Brescia, Brescia, Italy.
McCartney A; 'Sandro Pitigliani' Department of Medical Oncology, Hospital of Prato, ASL Toscana Centro, Prato, Italy.
Minisini AM; Department of Oncology, Azienda Ospedaliero Universitaria Integrata di Udine, Udine, Italy.
Caremoli ER; Cancer Centre, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy.
Spazzapan S; Unit of Medical Oncology and Cancer Prevention, IRCCS CRO di Aviano, National Cancer Institute, Aviano, Italy.
Magnolfi E; Department of Medical Oncology, Hospital Civile SS Trinità di Sora, Frosinone, Italy.
Brunello A; Department of Medical Oncology, Veneto Institute of Oncology IOV Padova, Padua, Italy.
Risi E; 'Sandro Pitigliani' Department of Medical Oncology, Hospital of Prato, ASL Toscana Centro, Prato, Italy.
Palumbo R; Department of Medical Oncology, IRCCS ICS Maugeri, Pavia, Italy.
Leo S; Department of Medical Oncology, Vito Fazzi Hospital, Lecce, Italy.
Colleoni M; Division of Medical Senology, IEO, European Institute of Oncology IRCCS, Milan, Italy.
Donati S; Department of Oncology, Versilia Hospital (Camaiore-Lu), Viareggio, Italy.
De Placido S; Department of Endocrinology and Molecular and Clinical Oncology, AOU Federico II, Naples, Italy.
Orlando L; Department of Medical Oncology, Perrino Hospital, ASL Brindisi, Brindisi, Italy.
Pistelli M; Department of Medical Oncology, Ospedali Riuniti di Ancona, Università Politecnica delle Marche, Ancona, Italy.
Parolin V; Department of Medical Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Mislang A; 'Sandro Pitigliani' Department of Medical Oncology, Hospital of Prato, ASL Toscana Centro, Prato, Italy.; Flinders Centre for Innovation in Cancer, Flinders Medical Centre, Bedford Park, South Australia, Australia.
Becheri D; Geriatric Medicine Unit, AUSL Toscana Centro, Prato, Italy.
Puglisi F; Department of Oncology, Azienda Ospedaliero Universitaria Integrata di Udine, Udine, Italy.; Unit of Medical Oncology and Cancer Prevention, IRCCS CRO di Aviano, National Cancer Institute, Aviano, Italy.
Sanna G; 'Sandro Pitigliani' Department of Medical Oncology, Hospital of Prato, ASL Toscana Centro, Prato, Italy.
Zafarana E; 'Sandro Pitigliani' Department of Medical Oncology, Hospital of Prato, ASL Toscana Centro, Prato, Italy.
Boni L; Clinical Trials Centre, AOU University Hospital Careggi, Florence, Italy.
Mottino G; Geriatric Medicine Unit, AUSL Toscana Centro, Prato, Italy.
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Źródło :
Breast cancer research : BCR [Breast Cancer Res] 2020 Aug 05; Vol. 22 (1), pp. 83. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Albumins/*therapeutic use
Breast Neoplasms/*drug therapy
Paclitaxel/*therapeutic use
Age Factors ; Aged ; Aged, 80 and over ; Albumins/adverse effects ; Antineoplastic Agents, Phytogenic/adverse effects ; Antineoplastic Agents, Phytogenic/therapeutic use ; Breast Neoplasms/pathology ; Dose-Response Relationship, Drug ; Female ; Humans ; Neoplasm Invasiveness ; Neoplasm Staging ; Paclitaxel/adverse effects ; Prognosis ; Survival Rate
Czasopismo naukowe

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