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Tytuł :
Effect of Freeze-Thaw Cycles on the Oxidation of Protein and Fat and Its Relationship with the Formation of Heterocyclic Aromatic Amines and Advanced Glycation End Products in Raw Meat.
Autorzy :
Wu X; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
Zhang Z; State Key Laboratory of Food Safety Technology for Meat Products, Yinxiang Group, Xianmen 361100, China.
He Z; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
Wang Z; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
Qin F; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
Zeng M; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
Chen J; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 26; Vol. 26 (5). Date of Electronic Publication: 2021 Feb 26.
Typ publikacji :
Journal Article
MeSH Terms :
Adipose Tissue/*metabolism
Amines/*metabolism
Heterocyclic Compounds/*metabolism
Proteins/*metabolism
Amines/chemistry ; Animals ; Chickens ; Cooking ; Freezing/adverse effects ; Heterocyclic Compounds/chemistry ; Humans ; Maillard Reaction ; Meat/analysis ; Oxidation-Reduction ; Pork Meat/analysis ; Swine ; Thiobarbituric Acid Reactive Substances/chemistry ; Thiobarbituric Acid Reactive Substances/metabolism
Czasopismo naukowe
Tytuł :
A simultaneous exploratory and quantitative amino acid and biogenic amine metabolic profiling platform for rapid disease phenotyping via UPLC-QToF-MS.
Autorzy :
Gray N; Australian National Phenome Centre, Health Futures Institute, Murdoch University, Harry Perkins South Building, Perth, WA, 6150, Australia; Center for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Murdoch Perth, WA, 6150, Australia.
Lawler NG; Australian National Phenome Centre, Health Futures Institute, Murdoch University, Harry Perkins South Building, Perth, WA, 6150, Australia; Center for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Murdoch Perth, WA, 6150, Australia.
Yang R; Australian National Phenome Centre, Health Futures Institute, Murdoch University, Harry Perkins South Building, Perth, WA, 6150, Australia.
Morillon AC; Australian National Phenome Centre, Health Futures Institute, Murdoch University, Harry Perkins South Building, Perth, WA, 6150, Australia.
Gay MCL; Bruker Pty Ltd, Preston, VIC, 3072, Australia.
Bong SH; Australian National Phenome Centre, Health Futures Institute, Murdoch University, Harry Perkins South Building, Perth, WA, 6150, Australia.
Holmes E; Australian National Phenome Centre, Health Futures Institute, Murdoch University, Harry Perkins South Building, Perth, WA, 6150, Australia; Center for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Murdoch Perth, WA, 6150, Australia; Section for Nutrition Research, Imperial College London, Sir Alexander Fleming Building, South Kensington, London, SW72AZ, UK.
Nicholson JK; Australian National Phenome Centre, Health Futures Institute, Murdoch University, Harry Perkins South Building, Perth, WA, 6150, Australia; Center for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Murdoch Perth, WA, 6150, Australia; Institute of Global Health Innovation, Imperial College London, Level 1, Faculty Building South Kensington Campus, London, SW72NA, UK. Electronic address: .
Whiley L; Australian National Phenome Centre, Health Futures Institute, Murdoch University, Harry Perkins South Building, Perth, WA, 6150, Australia; Center for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Murdoch Perth, WA, 6150, Australia; The Perron Institute for Neurological and Translational Science, Nedlands, WA, 6009, Australia. Electronic address: .
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Źródło :
Talanta [Talanta] 2021 Feb 01; Vol. 223 (Pt 2), pp. 121872. Date of Electronic Publication: 2020 Nov 07.
Typ publikacji :
Journal Article
MeSH Terms :
Amino Acids/*metabolism
Biogenic Amines/*metabolism
Amino Acids/blood ; Biogenic Amines/blood ; COVID-19/blood ; COVID-19/urine ; Chromatography, High Pressure Liquid ; Humans ; Mass Spectrometry ; Metabolomics ; Phenotype ; Quality Control ; Reference Standards ; Reproducibility of Results ; Retrospective Studies
Czasopismo naukowe
Tytuł :
An Integrated Cofactor/Co-Product Recycling Cascade for the Biosynthesis of Nylon Monomers from Cycloalkylamines.
Autorzy :
Sarak S; Department of Systems Biotechnology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 050-29, South Korea.
Sung S; Department of Systems Biotechnology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 050-29, South Korea.
Jeon H; Department of Systems Biotechnology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 050-29, South Korea.
Patil MD; Department of Systems Biotechnology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 050-29, South Korea.
Khobragade TP; Department of Systems Biotechnology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 050-29, South Korea.
Pagar AD; Department of Systems Biotechnology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 050-29, South Korea.
Dawson PE; Department of Chemistry, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA, 92037, USA.
Yun H; Department of Systems Biotechnology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 050-29, South Korea.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Feb 15; Vol. 60 (7), pp. 3481-3486. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amines/*metabolism
Nylons/*metabolism
Amines/chemistry ; Metabolic Engineering ; Nylons/chemistry
Czasopismo naukowe
Tytuł :
Isoamylamine Induces B16-F1 Melanoma Cell Autophagy by Upregulating the 5' Adenosine Monophosphate-Activated Protein Pathway.
Autorzy :
Peng YC; Department of Internal Medicine, Chiayi Branch of Taichung Veterans General Hospital, Chiayi, Taiwan.; Division of Gastroenterology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Wang SR; Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.
Lai YF; Department of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan.
Tsai NM; Department of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan.
Lin KL; Department of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan.
Lin SJ; Department of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan.
Yang TP; Department of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan.
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Źródło :
Journal of medicinal food [J Med Food] 2021 Feb; Vol. 24 (2), pp. 188-196.
Typ publikacji :
Journal Article
MeSH Terms :
AMP-Activated Protein Kinases*/genetics
AMP-Activated Protein Kinases*/metabolism
Amines*/pharmacology
Autophagy*/drug effects
Up-Regulation*/drug effects
Animals ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Mice ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
A review of gas chromatographic techniques for identification of aqueous amine degradation products in carbonated environments.
Autorzy :
Saeed IM; Department of Chemical Engineering, Faculty of Engineering, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Mazari SA; Department of Chemical Engineering, Dawood University of Engineering and Technology, New M.A. Jinnah Road, Karachi, 74800, Pakistan. .
Alaba P; Department of Chemical Engineering, Ahmadu Bello University, Zaria, Nigeria.
Ali BS; Department of Chemical Engineering, Faculty of Engineering, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Jan BM; Department of Chemical Engineering, Faculty of Engineering, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Basirun WJ; Department of Chemistry, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Sani YM; Department of Chemical Engineering, Ahmadu Bello University, Zaria, Nigeria.
Nizzamuddin S; Intelligent Materials for Road and Airport Pavements (I-RAP) Research Group, Civil & Infrastructure Engineering, Royal Melbourne Institute of Technology (RMIT) University, 124 La Trobe St., Melbourne, VIC, 3000, Australia.
Mubarak NM; Department of Chemical Engineering, Faculty of Engineering and Science, Curtin University, 9800, Miri, Sarawak, Malaysia. .
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2021 Feb; Vol. 28 (6), pp. 6324-6348. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Amines*
Carbon Dioxide*
Carbonates ; Chromatography, Gas ; Water
Czasopismo naukowe
Tytuł :
Inhibitory effects of Portulaca oleracea L. and selected flavonoid ingredients on heterocyclic amines in roast beef patties and Density Function Theory calculation of binding between heterocyclic amines intermediates and flavonoids.
Autorzy :
Jing J; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa 999078, Macau; School of Pharmacy, Zunyi Medical University, Zunyi 563000, China.
He Y; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Nationalities University, Kunming 650500, China.
Wang Y; Key Laboratory of Traditional Chinese Medicine Quality and Standard, Gansu University of Chinese Medicine, Lanzhou 730101, China.
Zeng M; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Jan 30; Vol. 336, pp. 127551. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji :
Journal Article
MeSH Terms :
Amines/*chemistry
Flavonoids/*chemistry
Portulaca/*chemistry
Red Meat/*analysis
Amines/analysis ; Amines/metabolism ; Animals ; Antioxidants/chemistry ; Cattle ; Chromatography, High Pressure Liquid ; Density Functional Theory ; Heterocyclic Compounds/chemistry ; Portulaca/metabolism ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Contents of Functionally Bioactive Peptides, Free Amino Acids, and Biogenic Amines in Dutch-Type Cheese Models Produced with Different Lactobacilli.
Autorzy :
Garbowska M; Division of Milk Technology, Department of Food Technology and Assessment, Institute of Food Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159c Street, 02-776 Warsaw, Poland.
Pluta A; Division of Milk Technology, Department of Food Technology and Assessment, Institute of Food Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159c Street, 02-776 Warsaw, Poland.
Berthold-Pluta A; Division of Milk Technology, Department of Food Technology and Assessment, Institute of Food Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159c Street, 02-776 Warsaw, Poland.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Nov 22; Vol. 25 (22). Date of Electronic Publication: 2020 Nov 22.
Typ publikacji :
Journal Article
MeSH Terms :
Amino Acids/*analysis
Biogenic Amines/*analysis
Cheese/*microbiology
Lactobacillus/*metabolism
Peptides/*analysis
Amino Acids/biosynthesis ; Amino Acids/chemistry ; Animals ; Biogenic Amines/biosynthesis ; Biogenic Amines/chemistry ; Carnosine/analysis ; Carnosine/metabolism ; Cheese/analysis ; Fermentation ; Food Handling/methods ; Food Microbiology/methods ; Food Quality ; Milk/chemistry ; Milk/microbiology ; Netherlands ; Peptides/chemistry ; Peptides/metabolism ; Proteolysis ; Time Factors
Czasopismo naukowe
Tytuł :
Ultrasound-assisted dispersive solid-phase extraction combined with reversed-phase high-performance liquid chromatography-photodiode array detection for the determination of nine biogenic amines in canned seafood.
Autorzy :
Wang J; Shanghai Engineering Research Center of Aquatic Product Processing and Preservation, College of Food Science and Technology, Shanghai Ocean University, Shanghai 200120, China.
Liu Z; Key Laboratory of Oceanic and Polar Fisheries, Ministry of Agriculture and Rural Affair, East China Sea Fishery Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China. Electronic address: .
Qu Y; Shanghai Engineering Research Center of Aquatic Product Processing and Preservation, College of Food Science and Technology, Shanghai Ocean University, Shanghai 200120, China. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2021 Jan 11; Vol. 1636, pp. 461768. Date of Electronic Publication: 2020 Nov 30.
Typ publikacji :
Journal Article
MeSH Terms :
Biogenic Amines/*analysis
Chromatography, High Pressure Liquid/*methods
Seafood/*analysis
Animals ; Biogenic Amines/isolation & purification ; Chromatography, Reverse-Phase ; Limit of Detection ; Solid Phase Extraction ; Solvents/chemistry ; Sonication
Czasopismo naukowe
Tytuł :
Technological roles of microorganisms in fish fermentation: a review.
Autorzy :
Xu Y; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.
Zang J; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.
Regenstein JM; Department of Food Science, Cornell University, Ithaca, New York, USA.
Xia W; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.
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Źródło :
Critical reviews in food science and nutrition [Crit Rev Food Sci Nutr] 2021; Vol. 61 (6), pp. 1000-1012. Date of Electronic Publication: 2020 Apr 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biogenic Amines*
Fish Products*
Animals ; Fermentation ; Fishes ; Taste
Czasopismo naukowe
Tytuł :
In vitro bioaccessibility of amino acids and bioactive amines in 70% cocoa dark chocolate: What you eat and what you get.
Autorzy :
Dala-Paula BM; Laboratório de Nutrição Experimental, Faculdade de Nutrição, Universidade Federal de Alfenas, Alfenas, MG 37130-000, Brazil.
Deus VL; LBqA and CEDAFAR, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos 6627, Belo Horizonte, MG 31270-901, Brazil.
Tavano OL; Laboratório de Nutrição Experimental, Faculdade de Nutrição, Universidade Federal de Alfenas, Alfenas, MG 37130-000, Brazil.
Gloria MBA; LBqA and CEDAFAR, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos 6627, Belo Horizonte, MG 31270-901, Brazil; Departamento de Ciências do Consumo, UFRPE - Universidade Federal Rural de Pernambuco, Rua Dom Manuel de Medeiros, s/n, Dois Irmãos, 52171-900 Recife, PE, Brazil. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 May 01; Vol. 343, pp. 128397. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article
MeSH Terms :
Amines/*metabolism
Amino Acids/*metabolism
Cacao/*metabolism
Chocolate/*analysis
Amines/analysis ; Amino Acids/analysis ; Ammonia/metabolism ; Cacao/chemistry ; Chromatography, High Pressure Liquid ; Cluster Analysis ; Histamine/analysis ; Histamine/metabolism ; Humans ; Nutritive Value ; Polyamines/analysis ; Polyamines/metabolism ; Principal Component Analysis ; gamma-Aminobutyric Acid/analysis
Czasopismo naukowe
Tytuł :
Designed multifunctional visual observation of magnetic ionic liquid coupling with microwave-assisted derivatization for determination of biogenic amines.
Autorzy :
Cao D; College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang 110036, China; Department of Mechanical and Power Engineering, Yingkou Institute of Technology, Yingkou 115014, China.
Xu X; College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang 110036, China. Electronic address: .
Feng X; College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang 110036, China.
Zhang L; College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang 110036, China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2020 Dec 15; Vol. 333, pp. 127518. Date of Electronic Publication: 2020 Jul 10.
Typ publikacji :
Journal Article
MeSH Terms :
Magnetics*
Microwaves*
Biogenic Amines/*isolation & purification
Ionic Liquids/*chemistry
Liquid Phase Microextraction/*methods
Animals ; Beer/analysis ; Biogenic Amines/analysis ; Chromatography, High Pressure Liquid ; Hydrophobic and Hydrophilic Interactions ; Limit of Detection ; Milk/chemistry
Czasopismo naukowe
Tytuł :
Behaviour of Vascular Smooth Muscle Cells on Amine Plasma-Coated Materials with Various Chemical Structures and Morphologies.
Autorzy :
Nemcakova I; Laboratory of Biomaterials and Tissue Engineering, Institute of Physiology of the Czech Academy of Sciences, v.v.i., Videnska 1083, 142 20 Prague 4, Czech Republic.
Blahova L; Central European Institute of Technology-CEITEC, Masaryk University, Kamenice 5, 625 00 Brno, Czech Republic.
Rysanek P; Department of Physics, Faculty of Science, University of J. E. Purkyne in Usti nad Labem, Pasteurova 15, 400 96 Usti nad Labem, Czech Republic.
Blanquer A; Laboratory of Biomaterials and Tissue Engineering, Institute of Physiology of the Czech Academy of Sciences, v.v.i., Videnska 1083, 142 20 Prague 4, Czech Republic.
Bacakova L; Laboratory of Biomaterials and Tissue Engineering, Institute of Physiology of the Czech Academy of Sciences, v.v.i., Videnska 1083, 142 20 Prague 4, Czech Republic.
Zajíčková L; Central European Institute of Technology-CEITEC, Masaryk University, Kamenice 5, 625 00 Brno, Czech Republic.; Department of Physical Electronics, Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno, Czech Republic.; Central European Institute of Technology-CEITEC, Brno University of Technology, Purkynova 123, 612 00 Brno, Czech Republic.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 12; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 12.
Typ publikacji :
Journal Article
MeSH Terms :
Amines/*chemistry
Coated Materials, Biocompatible/*pharmacology
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Nanofibers/*chemistry
Plasma/*chemistry
Polymers/*chemistry
Amines/adverse effects ; Amines/immunology ; Amines/pharmacology ; Animals ; Cell Adhesion/drug effects ; Cell Adhesion/immunology ; Cell Proliferation/drug effects ; Cells, Cultured ; Coated Materials, Biocompatible/adverse effects ; Coated Materials, Biocompatible/chemistry ; Macrophages/drug effects ; Macrophages/metabolism ; Mice ; Muscle, Smooth, Vascular/cytology ; Muscle, Smooth, Vascular/growth & development ; Myocytes, Smooth Muscle/metabolism ; Nanofibers/adverse effects ; Photoelectron Spectroscopy ; Plasma/immunology ; Polyesters/chemistry ; Polymers/adverse effects ; Polymers/pharmacology ; RAW 264.7 Cells ; Rats ; Surface Properties/drug effects ; Tissue Scaffolds/adverse effects ; Tissue Scaffolds/chemistry
Czasopismo naukowe
Tytuł :
Synthesis and characterisation of thiobarbituric acid enamine derivatives, and evaluation of their α-glucosidase inhibitory and anti-glycation activity.
Autorzy :
Ali M; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Barakat A; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.; Department of Chemistry, Faculty of Science, Alexandria University, Ibrahimia, Egypt.
El-Faham A; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.; Department of Chemistry, Faculty of Science, Alexandria University, Ibrahimia, Egypt.
Al-Rasheed HH; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Dahlous K; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Al-Majid AM; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Sharma A; Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban, South Africa.; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Yousuf S; H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan.
Sanam M; Dr. Panjwani Center for Molecular medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan.
Ul-Haq Z; Dr. Panjwani Center for Molecular medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan.
Choudhary MI; H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan.; Dr. Panjwani Center for Molecular medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan.
de la Torre BG; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Albericio F; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.; Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban, South Africa.; CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, and Department of Organic Chemistry, University of Barcelona, Barcelona, Spain.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 692-701.
Typ publikacji :
Journal Article
MeSH Terms :
Amines/*pharmacology
Glycoside Hydrolase Inhibitors/*pharmacology
Thiobarbiturates/*pharmacology
alpha-Glucosidases/*metabolism
Amines/chemical synthesis ; Amines/chemistry ; Dose-Response Relationship, Drug ; Glycoside Hydrolase Inhibitors/chemical synthesis ; Glycoside Hydrolase Inhibitors/chemistry ; Glycosylation/drug effects ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship ; Thiobarbiturates/chemical synthesis ; Thiobarbiturates/chemistry
Czasopismo naukowe
Tytuł :
Pharmacodynamics and pharmacokinetics of DWP14012 (fexuprazan) in healthy subjects with different ethnicities.
Autorzy :
Hwang JG; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.
Jeon I; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.
Park SA; Daewoong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Lee A; Daewoong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Yu KS; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.
Jang IJ; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.
Lee S; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.
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Źródło :
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2020 Dec; Vol. 52 (11-12), pp. 1648-1657. Date of Electronic Publication: 2020 Oct 27.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Amines/*administration & dosage
Gastric Acid/*metabolism
Pyrroles/*administration & dosage
Adult ; Amines/pharmacokinetics ; Amines/pharmacology ; Asian Continental Ancestry Group ; Double-Blind Method ; European Continental Ancestry Group ; Female ; Humans ; Male ; Pyrroles/pharmacokinetics ; Pyrroles/pharmacology ; Young Adult
Czasopismo naukowe
Tytuł :
Process improvement to prevent the formation of biogenic amines during soy sauce brewing.
Autorzy :
Li J; Life Science College, China Jiliang University, Hangzhou 310018, China. Electronic address: .
Jiang K; Zhejiang Institute of Product Quality and Safety Inspection, Hangzhou 310000, China. Electronic address: .
Huang H; Life Science College, China Jiliang University, Hangzhou 310018, China. Electronic address: .
Cheng H; School of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. Electronic address: .
Ye X; School of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. Electronic address: .
Zhi Z; Ghent University, Gent 9000, Belgium. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2020 Nov 30; Vol. 331, pp. 127347. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Soy Foods*/analysis
Biogenic Amines/*biosynthesis
Biogenic Amines/analysis ; Cadaverine/analysis ; Cadaverine/metabolism ; Fermentation ; Food-Processing Industry/methods ; Histamine/analysis ; Histamine/metabolism ; Putrescine/analysis ; Putrescine/metabolism ; Sodium Chloride ; Temperature
Czasopismo naukowe
Tytuł :
Design and Scalable Synthesis of N-Alkylhydroxylamine Reagents for the Direct Iron-Catalyzed Installation of Medicinally Relevant Amines*.
Autorzy :
Falk E; Laboratorium für Organische Chemie, ETH Zürich, Vladimir-Prelog-Weg 3, HCI, 8093, Zürich, Switzerland.
Makai S; Laboratorium für Organische Chemie, ETH Zürich, Vladimir-Prelog-Weg 3, HCI, 8093, Zürich, Switzerland.
Delcaillau T; Laboratorium für Organische Chemie, ETH Zürich, Vladimir-Prelog-Weg 3, HCI, 8093, Zürich, Switzerland.
Gürtler L; Laboratorium für Organische Chemie, ETH Zürich, Vladimir-Prelog-Weg 3, HCI, 8093, Zürich, Switzerland.
Morandi B; Laboratorium für Organische Chemie, ETH Zürich, Vladimir-Prelog-Weg 3, HCI, 8093, Zürich, Switzerland.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2020 Nov 16; Vol. 59 (47), pp. 21064-21071. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amines/*chemical synthesis
Hydroxylamine/*chemical synthesis
Iron/*chemistry
Alkenes/chemistry ; Amines/chemistry ; Catalysis ; Drug Design ; Hydroxylamine/chemistry ; Molecular Structure
Czasopismo naukowe
Tytuł :
Acylated 1 H -1,2,4-Triazol-5-amines Targeting Human Coagulation Factor XIIa and Thrombin: Conventional and Microscale Synthesis, Anticoagulant Properties, and Mechanism of Action.
Autorzy :
Korff M; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstraße 48, 48149 Münster, Germany.
Imberg L; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstraße 48, 48149 Münster, Germany.
Will JM; Institute of Inorganic and Analytical Chemistry, University of Münster, Corrensstraße 30, 48149 Münster, Germany.
Bückreiß N; Pharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany.
Kalinina SA; Institute of Food Chemistry, University of Münster, Corrensstraße 45, 48149 Münster, Germany.
Wenzel BM; Department of Pharmacy, Institute of Pharmaceutical Chemistry, Philipps University Marburg, Marbacher Weg 6, 35032 Marburg, Germany.
Kastner GA; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstraße 48, 48149 Münster, Germany.
Daniliuc CG; Institute for Organic Chemistry, University of Münster, Corrensstraße 40, 48149 Münster, Germany.
Barth M; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstraße 48, 48149 Münster, Germany.
Ovsepyan RA; Laboratory of Translational Medicine, Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, and Immunology, Samory Mashela str. 1, GSP-7, 117997 Moscow, Russia.; Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, 4 Kosygina St, 119991 Moscow, Russia.
Butov KR; Laboratory of Translational Medicine, Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, and Immunology, Samory Mashela str. 1, GSP-7, 117997 Moscow, Russia.; Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, 4 Kosygina St, 119991 Moscow, Russia.
Humpf HU; Institute of Food Chemistry, University of Münster, Corrensstraße 45, 48149 Münster, Germany.
Lehr M; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstraße 48, 48149 Münster, Germany.
Panteleev MA; Laboratory of Translational Medicine, Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, and Immunology, Samory Mashela str. 1, GSP-7, 117997 Moscow, Russia.; Faculty of Physics, Lomonosov Moscow State University, 1/2 Leninskie gory, 119991 Moscow, Russia.; Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, 4 Kosygina St, 119991 Moscow, Russia.; Faculty of Biological and Medical Physics, Moscow Institute of Physics and Technology, 9 Institutskii per., 141700 Dolgoprudnyi, Russia.
Poso A; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, 70211 Kuopio, Finland.; Department of Internal Medicine VIII, University Hospital Tübingen, 72076 Tübingen, Germany.
Karst U; Institute of Inorganic and Analytical Chemistry, University of Münster, Corrensstraße 30, 48149 Münster, Germany.
Steinmetzer T; Department of Pharmacy, Institute of Pharmaceutical Chemistry, Philipps University Marburg, Marbacher Weg 6, 35032 Marburg, Germany.
Bendas G; Pharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany.
Kalinin DV; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstraße 48, 48149 Münster, Germany.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Nov 12; Vol. 63 (21), pp. 13159-13186. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article
MeSH Terms :
Amines/*chemistry
Anticoagulants/*pharmacology
Blood Coagulation/*drug effects
Factor XIIa/*metabolism
Thrombin/*metabolism
Amines/chemical synthesis ; Amines/metabolism ; Anticoagulants/chemical synthesis ; Anticoagulants/metabolism ; Binding Sites ; Catalytic Domain ; Cell Line, Tumor ; Cell Survival/drug effects ; Factor XIIa/antagonists & inhibitors ; Humans ; Inhibitory Concentration 50 ; Molecular Dynamics Simulation ; Platelet Aggregation/drug effects ; Structure-Activity Relationship ; Thrombin/antagonists & inhibitors ; Triazoles/chemistry
Czasopismo naukowe
Tytuł :
N -Trifluoromethyl Amines and Azoles: An Underexplored Functional Group in the Medicinal Chemist's Toolbox.
Autorzy :
Schiesser S; Department of Medicinal Chemistry, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Pepparedsleden 1, 43183 Mölndal, Sweden.
Chepliaka H; Department of Medicinal Chemistry, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Pepparedsleden 1, 43183 Mölndal, Sweden.; Department of Chemistry, Ludwig-Maximilians Universität München, Butenandstrasse 5-13, 81377 Munich, Germany.
Kollback J; Department of Medicinal Chemistry, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Pepparedsleden 1, 43183 Mölndal, Sweden.; Department of Chemistry and Molecular Biology, Göteborgs universitet, Kemigården 4, 41296 Gothenburg, Sweden.
Quennesson T; Department of Medicinal Chemistry, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Pepparedsleden 1, 43183 Mölndal, Sweden.; Université de Lille, Institut Pasteur de Lille, INSERM U1177 - Drugs and Molecules for Living Systems, 59000 Lille, France.
Czechtizky W; Department of Medicinal Chemistry, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Pepparedsleden 1, 43183 Mölndal, Sweden.
Cox RJ; Department of Medicinal Chemistry, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Pepparedsleden 1, 43183 Mölndal, Sweden.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Nov 12; Vol. 63 (21), pp. 13076-13089. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amines/*chemistry
Azoles/*chemistry
Fluorine/*chemistry
Amines/chemical synthesis ; Amines/pharmacokinetics ; Azoles/chemical synthesis ; Azoles/pharmacokinetics ; Caco-2 Cells ; Drug Design ; Drug Stability ; Glutathione/chemistry ; Half-Life ; Humans ; Hydrogen-Ion Concentration
Czasopismo naukowe
Tytuł :
Design, synthesis, and pharmacological evaluation of novel 1,2,4-triazol-3-amine derivatives as potential agonists of GABA A subtype receptors with anticonvulsant and hypnotic effects.
Autorzy :
Jahani R; Department of Pharmacology and Toxicology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Reza Abtahi S; Department of Pharmacology and Toxicology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Nematpour M; Department of Chemistry, Tarbiat Modares University, Tehran, Iran.
Fasihi Dastjerdi H; Department of Pharmaceutical Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Biomaterial and Medicinal Chemistry Research Center, Aja University of Medical Science, Tehran, Iran.
Chamanara M; Department of Pharmacology and Toxicology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Hami Z; Department of Pharmacology and Toxicology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Paknejad B; Department of Pharmacology and Toxicology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2020 Nov; Vol. 104, pp. 104212. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article
MeSH Terms :
Amines/*pharmacology
Anticonvulsants/*pharmacology
Hypnotics and Sedatives/*pharmacology
Receptors, GABA-A/*metabolism
Seizures/*drug therapy
Triazoles/*pharmacology
Amines/chemical synthesis ; Amines/chemistry ; Animals ; Anticonvulsants/chemical synthesis ; Anticonvulsants/chemistry ; Dose-Response Relationship, Drug ; Drug Design ; Electroshock ; Hypnotics and Sedatives/chemical synthesis ; Hypnotics and Sedatives/chemistry ; Male ; Mice ; Molecular Structure ; Pentylenetetrazole ; Seizures/chemically induced ; Sleepiness ; Structure-Activity Relationship ; Triazoles/chemical synthesis ; Triazoles/chemistry
Czasopismo naukowe
Tytuł :
QSAR Assessing the Efficiency of Antioxidants in the Termination of Radical-Chain Oxidation Processes of Organic Compounds.
Autorzy :
Khairullina V; Faculty of Chemistry, Bashkir State University, 450076 Ufa, Russia.
Safarova I; Faculty of Chemistry, Bashkir State University, 450076 Ufa, Russia.
Sharipova G; Faculty of Chemistry, Bashkir State University, 450076 Ufa, Russia.
Martynova Y; Faculty of Chemistry, Bashkir State University, 450076 Ufa, Russia.
Gerchikov A; Faculty of Chemistry, Bashkir State University, 450076 Ufa, Russia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jan 14; Vol. 26 (2). Date of Electronic Publication: 2021 Jan 14.
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Amines/*pharmacology
Aminophenols/*pharmacology
Antioxidants/*pharmacology
Phenols/*pharmacology
Uracil/*pharmacology
Amines/chemistry ; Aminophenols/chemistry ; Antioxidants/chemistry ; Models, Molecular ; Oxidation-Reduction ; Phenols/chemistry ; Quantitative Structure-Activity Relationship ; Uracil/chemistry
Czasopismo naukowe

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