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Tytuł:
KEGG orthology prediction of bacterial proteins using natural language processing.
Autorzy:
Chen J; School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi, China.; Jiangsu Provincial Engineering Laboratory of Pattern Recognition and Computing Intelligence, Jiangnan University, Wuxi, China.
Wu H; School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi, China.
Wang N; School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi, China. .
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2024 Apr 11; Vol. 25 (1), pp. 146. Date of Electronic Publication: 2024 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Natural Language Processing*
Bacterial Proteins*
Genome ; Molecular Sequence Annotation ; Amino Acid Sequence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evolution-inspired engineering of nonribosomal peptide synthetases.
Autorzy:
Bozhüyük KAJ; Max Planck Institute for Terrestrial Microbiology, Department of Natural Products in Organismic Interactions, 35043 Marburg, Germany.; Molecular Biotechnology, Department of Biosciences, Goethe-University Frankfurt, 60438 Frankfurt, Germany.; Myria Biosciences AG, Tech Park Basel, Hochbergstrasse 60C, 4057 Basel, Switzerland.
Präve L; Max Planck Institute for Terrestrial Microbiology, Department of Natural Products in Organismic Interactions, 35043 Marburg, Germany.; Molecular Biotechnology, Department of Biosciences, Goethe-University Frankfurt, 60438 Frankfurt, Germany.
Kegler C; Max Planck Institute for Terrestrial Microbiology, Department of Natural Products in Organismic Interactions, 35043 Marburg, Germany.; Molecular Biotechnology, Department of Biosciences, Goethe-University Frankfurt, 60438 Frankfurt, Germany.
Schenk L; Max Planck Institute for Terrestrial Microbiology, Department of Natural Products in Organismic Interactions, 35043 Marburg, Germany.; Molecular Biotechnology, Department of Biosciences, Goethe-University Frankfurt, 60438 Frankfurt, Germany.
Kaiser S; Max Planck Institute for Terrestrial Microbiology, Department of Natural Products in Organismic Interactions, 35043 Marburg, Germany.; Evolutionary Biochemistry Group, Max Planck Institute for Terrestrial Microbiology, 35043 Marburg, Germany.
Schelhas C; Max Planck Institute for Terrestrial Microbiology, Department of Natural Products in Organismic Interactions, 35043 Marburg, Germany.
Shi YN; Molecular Biotechnology, Department of Biosciences, Goethe-University Frankfurt, 60438 Frankfurt, Germany.
Kuttenlochner W; Chair of Biochemistry, Center for Protein Assemblies, Technical University of Munich, Ernst-Otto-Fischer-Straße 8, 85748 Garching, Germany.
Schreiber M; Max Planck Institute for Terrestrial Microbiology, Department of Natural Products in Organismic Interactions, 35043 Marburg, Germany.; Molecular Biotechnology, Department of Biosciences, Goethe-University Frankfurt, 60438 Frankfurt, Germany.
Kandler J; Molecular Biotechnology, Department of Biosciences, Goethe-University Frankfurt, 60438 Frankfurt, Germany.
Alanjary M; Bioinformatics Group, Wageningen University, Droevendaalsesteeg 1, 6708PB Wageningen, The Netherlands.
Mohiuddin TM; Molecular Biotechnology, Department of Biosciences, Goethe-University Frankfurt, 60438 Frankfurt, Germany.
Groll M; Chair of Biochemistry, Center for Protein Assemblies, Technical University of Munich, Ernst-Otto-Fischer-Straße 8, 85748 Garching, Germany.
Hochberg GKA; Evolutionary Biochemistry Group, Max Planck Institute for Terrestrial Microbiology, 35043 Marburg, Germany.; Center for Synthetic Microbiology (SYNMIKRO), Phillips University Marburg, 35043 Marburg, Germany.; Department of Chemistry, Phillips University Marburg, 35043 Marburg, Germany.
Bode HB; Max Planck Institute for Terrestrial Microbiology, Department of Natural Products in Organismic Interactions, 35043 Marburg, Germany.; Molecular Biotechnology, Department of Biosciences, Goethe-University Frankfurt, 60438 Frankfurt, Germany.; Center for Synthetic Microbiology (SYNMIKRO), Phillips University Marburg, 35043 Marburg, Germany.; Department of Chemistry, Phillips University Marburg, 35043 Marburg, Germany.; LOEWE Centre for Translational Biodiversity Genomics (LOEWE-TBG) & Senckenberg Gesellschaft für Naturforschung, 60325 Frankfurt, Germany.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar 22; Vol. 383 (6689), pp. eadg4320. Date of Electronic Publication: 2024 Mar 22.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Synthases*/chemistry
Peptide Synthases*/classification
Peptide Synthases*/genetics
Protein Engineering*
Evolution, Molecular*
Bacterial Proteins*/chemistry
Bacterial Proteins*/classification
Bacterial Proteins*/genetics
Phylogeny ; Amino Acid Sequence/genetics ; Sequence Analysis, Protein
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of the C-Terminal β Sandwich of Thermoanaerobacter tengcongensis Thermophilic Esterase in Hydrolysis of Long-Chain Acyl Substrates.
Autorzy:
Joel EB; School of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.; Department of Biochemistry, Faculty of Basic Medical Sciences, University of Jos, Jos 930003, Nigeria.
Aberuagba A; School of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.; Department of Biological Sciences, McPherson University, Seriki-Sotayo 110117, Nigeria.
Bello AJ; School of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.
Akanbi-Gada M; School of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.
Igunnu A; Department of Biochemistry, Faculty of Life Sciences, University of Ilorin, Ilorin 234031, Nigeria.
Malomo SO; Department of Biochemistry, Faculty of Life Sciences, University of Ilorin, Ilorin 234031, Nigeria.
Olorunniji FJ; School of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 20; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 20.
Typ publikacji:
Journal Article
MeSH Terms:
Esterases*/metabolism
Bacterial Proteins*/metabolism
Firmicutes*
Amino Acid Sequence ; Hydrolysis ; Thermoanaerobacter/genetics ; Thermoanaerobacter/chemistry ; Enzyme Stability ; Substrate Specificity ; Cloning, Molecular
SCR Organism:
Caldanaerobacter subterraneus subsp. tengcongensis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Early Molecular Insights into Thanatin Analogues Binding to A. baumannii LptA.
Autorzy:
Oi KK; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Moehle K; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Schuster M; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Zerbe O; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 25; Vol. 28 (11). Date of Electronic Publication: 2023 May 25.
Typ publikacji:
Journal Article
MeSH Terms:
Antimicrobial Cationic Peptides*/chemistry
Acinetobacter baumannii*
Bacterial Proteins*/chemistry
Carrier Proteins*/chemistry
Anti-Bacterial Agents*/chemistry
Protein Binding ; Protein Conformation ; Amino Acid Sequence ; Conserved Sequence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Different CprABC amino acid sequences affect nisin A susceptibility in Clostridioides difficile isolates.
Autorzy:
Ide N; Department of General Dentistry, Hiroshima University Hospital, Hiroshima, Japan.
Kawada-Matsuo M; Department of Bacteriology, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.; Project Research Center for Nosocomial Infectious Diseases, Hiroshima University, Hiroshima, Japan.
Le MN; Department of Bacteriology, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.; Project Research Center for Nosocomial Infectious Diseases, Hiroshima University, Hiroshima, Japan.
Hisatsune J; Project Research Center for Nosocomial Infectious Diseases, Hiroshima University, Hiroshima, Japan.; Antimicrobial Resistance Research Centre, National Institute of Infectious Diseases, Higashi Murayama, Japan.
Nishi H; Department of General Dentistry, Hiroshima University Hospital, Hiroshima, Japan.
Hara T; Antimicrobial Resistance Research Centre, National Institute of Infectious Diseases, Higashi Murayama, Japan.; Section of Clinical Laboratory, Division of Clinical Support, Hiroshima University Hospital, Hiroshima, Japan.; Division of Laboratory Medicine, Hiroshima University Hospital, Hiroshima, Japan.
Kitamura N; Antimicrobial Resistance Research Centre, National Institute of Infectious Diseases, Higashi Murayama, Japan.
Kashiyama S; Antimicrobial Resistance Research Centre, National Institute of Infectious Diseases, Higashi Murayama, Japan.; Section of Clinical Laboratory, Division of Clinical Support, Hiroshima University Hospital, Hiroshima, Japan.; Division of Laboratory Medicine, Hiroshima University Hospital, Hiroshima, Japan.
Yokozaki M; Antimicrobial Resistance Research Centre, National Institute of Infectious Diseases, Higashi Murayama, Japan.; Division of Laboratory Medicine, Hiroshima University Hospital, Hiroshima, Japan.
Kawaguchi H; Department of General Dentistry, Hiroshima University Hospital, Hiroshima, Japan.
Ohge H; Antimicrobial Resistance Research Centre, National Institute of Infectious Diseases, Higashi Murayama, Japan.; Department of Infectious Diseases, Hiroshima University Hospital, Hiroshima, Japan.
Sugai M; Project Research Center for Nosocomial Infectious Diseases, Hiroshima University, Hiroshima, Japan.; Antimicrobial Resistance Research Centre, National Institute of Infectious Diseases, Higashi Murayama, Japan.
Komatsuzawa H; Department of Bacteriology, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.; Project Research Center for Nosocomial Infectious Diseases, Hiroshima University, Hiroshima, Japan.
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Źródło:
PloS one [PLoS One] 2023 Jan 20; Vol. 18 (1), pp. e0280676. Date of Electronic Publication: 2023 Jan 20 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Bacterial Agents*/pharmacology
Clostridioides difficile*/drug effects
Clostridium Infections*
Nisin*/pharmacology
Bacterial Proteins*/chemistry
Bacterial Proteins*/genetics
Bacterial Proteins*/metabolism
Drug Resistance, Bacterial*
Humans ; Amino Acid Sequence ; Microbial Sensitivity Tests ; Phylogeny
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Ros/MucR Zinc-Finger Protein Family in Bacteria: Structure and Functions.
Autorzy:
Janczarek M; Department of Industrial and Environmental Microbiology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, 19 Akademicka, 20-033 Lublin, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 08; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 08.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Bacterial Proteins*/metabolism
Zinc Fingers*/genetics
Phylogeny ; Amino Acid Sequence ; Transcription Factors/genetics ; Bacteria/metabolism ; Zinc/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structure of the hypothetical protein TTHA1873 from Thermus thermophilus.
Autorzy:
Yuvaraj I; Department of Computational and Data Sciences, Indian Institute of Science, Bangalore 560 012, India.
Chaudhary SK; Department of Computational and Data Sciences, Indian Institute of Science, Bangalore 560 012, India.
Jeyakanthan J; Structural Biology and Bio Computing Laboratory, Department of Bioinformatics, Alagappa University, Karaikudi 630 004, India.
Sekar K; Department of Computational and Data Sciences, Indian Institute of Science, Bangalore 560 012, India.
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Źródło:
Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2022 Sep 01; Vol. 78 (Pt 9), pp. 338-346. Date of Electronic Publication: 2022 Aug 30.
Typ publikacji:
Journal Article
MeSH Terms:
Bacterial Proteins*/chemistry
Thermus thermophilus*/chemistry
Amino Acid Sequence ; Binding Sites ; Crystallography, X-Ray
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Conformation of the N-Terminal Tails of Deinococcus grandis Dps Is Modulated by the Ionic Strength.
Autorzy:
Guerra JPL; Associate Laboratory i4HB, Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.; UCIBIO-Applied Molecular Biosciences Unit, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.
Blanchet CE; European Molecular Biology Laboratory, Hamburg Outstation, Notkestrasse 85, 22603 Hamburg, Germany.
Vieira BJC; Centro de Ciências e Tecnologias Nucleares, DECN, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, 2695-066 Bobadela, Portugal.
Almeida AV; Associate Laboratory i4HB, Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.; UCIBIO-Applied Molecular Biosciences Unit, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.
Waerenborgh JC; Centro de Ciências e Tecnologias Nucleares, DECN, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, 2695-066 Bobadela, Portugal.
Jones NC; ISA, Department of Physics and Astronomy, Aarhus University, DK-8000 Aarhus C, Denmark.
Hoffmann SV; ISA, Department of Physics and Astronomy, Aarhus University, DK-8000 Aarhus C, Denmark.
Tavares P; Associate Laboratory i4HB, Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.; UCIBIO-Applied Molecular Biosciences Unit, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.
Pereira AS; Associate Laboratory i4HB, Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.; UCIBIO-Applied Molecular Biosciences Unit, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Apr 28; Vol. 23 (9). Date of Electronic Publication: 2022 Apr 28.
Typ publikacji:
Journal Article
MeSH Terms:
Bacterial Proteins*/metabolism
Deinococcus*/genetics
Amino Acid Sequence ; DNA/metabolism ; Iron/metabolism ; Models, Molecular ; Osmolar Concentration
SCR Organism:
Deinococcus grandis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cryptococcal Protease(s) and the Activation of SARS-CoV-2 Spike (S) Protein.
Autorzy:
Mjokane N; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, Bloemfontein 9301, South Africa.
Maliehe M; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, Bloemfontein 9301, South Africa.
Folorunso OS; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, Bloemfontein 9301, South Africa.
Ogundeji AO; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, Bloemfontein 9301, South Africa.
Gcilitshana OMN; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, Bloemfontein 9301, South Africa.
Albertyn J; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, Bloemfontein 9301, South Africa.
Pohl CH; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, Bloemfontein 9301, South Africa.
Sebolai OM; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, Bloemfontein 9301, South Africa.
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Źródło:
Cells [Cells] 2022 Jan 27; Vol. 11 (3). Date of Electronic Publication: 2022 Jan 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aspartic Acid Proteases/*metabolism
Bacterial Proteins/*metabolism
Cryptococcus neoformans/*enzymology
SARS-CoV-2/*metabolism
Spike Glycoprotein, Coronavirus/*metabolism
Amino Acid Sequence ; Aspartic Acid Proteases/genetics ; Bacterial Proteins/genetics ; Binding Sites ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/virology ; Cryptococcus neoformans/genetics ; Fluorescent Dyes/chemistry ; Furin/genetics ; Furin/metabolism ; Humans ; Pandemics ; Peptides/chemistry ; Peptides/metabolism ; Proteolysis ; SARS-CoV-2/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of Helicobacter pylori Membrane Proteins Using Sequence-Based Features.
Autorzy:
Liu M; Ineye Hospital of Chengdu University of TCM, Chengdu University of TCM, Chengdu 610084, China.
Chen H; School of Healthcare Technology, Chengdu Neusoft University, 611844 Chengdu, China.
Gao D; School of Life Science and Technology and Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China.
Ma CY; School of Life Science and Technology and Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China.
Zhang ZY; School of Healthcare Technology, Chengdu Neusoft University, 611844 Chengdu, China.; School of Life Science and Technology and Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China.
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Źródło:
Computational and mathematical methods in medicine [Comput Math Methods Med] 2022 Jan 12; Vol. 2022, pp. 7493834. Date of Electronic Publication: 2022 Jan 12 (Print Publication: 2022).
Typ publikacji:
Evaluation Study; Journal Article; Validation Study
MeSH Terms:
Bacterial Proteins/*genetics
Helicobacter pylori/*genetics
Membrane Proteins/*genetics
Amino Acid Sequence ; Amino Acids/analysis ; Bacterial Proteins/chemistry ; Computational Biology ; Databases, Protein/statistics & numerical data ; Helicobacter pylori/chemistry ; Helicobacter pylori/pathogenicity ; Host Microbial Interactions ; Humans ; Membrane Proteins/chemistry ; Support Vector Machine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the Mycobacterium tuberculosis DprE1 Enzyme.
Autorzy:
Ezquerra-Aznárez JM; Department of Microbiology, Faculty of Medicine, University of Zaragoza, 50009 Zaragoza, Spain.
Degiacomi G; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, 27100 Pavia, Italy.
Gašparovič H; Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
Stelitano G; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, 27100 Pavia, Italy.
Sammartino JC; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, 27100 Pavia, Italy.
Korduláková J; Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
Governa P; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Manetti F; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Pasca MR; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, 27100 Pavia, Italy.
Chiarelli LR; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, 27100 Pavia, Italy.
Ramón-García S; Department of Microbiology, Faculty of Medicine, University of Zaragoza, 50009 Zaragoza, Spain.; Research & Development Agency of Aragon (ARAID) Foundation, 50018 Zaragoza, Spain.; CIBER Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029 Madrid, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 11; Vol. 23 (2). Date of Electronic Publication: 2022 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Alcohol Oxidoreductases/*antagonists & inhibitors
Antiparasitic Agents/*pharmacology
Antitubercular Agents/*pharmacology
Bacterial Proteins/*antagonists & inhibitors
Enzyme Inhibitors/*pharmacology
Ivermectin/*analogs & derivatives
Mycobacterium tuberculosis/*drug effects
Mycobacterium tuberculosis/*enzymology
Alcohol Oxidoreductases/genetics ; Amino Acid Sequence ; Bacterial Proteins/genetics ; Binding Sites ; Dose-Response Relationship, Drug ; Drug Discovery ; Ivermectin/pharmacology ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Mutation ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Multiple Antimicrobial Effects of Hybrid Peptides Synthesized Based on the Sequence of Ribosomal S1 Protein from Staphylococcus aureus .
Autorzy:
Kravchenko SV; Institute of Environmental and Agricultural Biology (X-BIO), Tyumen State University, 625003 Tyumen, Russia.
Domnin PA; Biology Faculty, Lomonosov Moscow State University, 119991 Moscow, Russia.; Gamaleya Research Centre of Epidemiology and Microbiology, 123098 Moscow, Russia.
Grishin SY; Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Russia.
Panfilov AV; Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Russia.
Azev VN; The Branch of the Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.
Mustaeva LG; The Branch of the Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.
Gorbunova EY; The Branch of the Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.
Kobyakova MI; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, 142290 Pushchino, Russia.
Surin AK; Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Russia.; The Branch of the Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.; State Research Center for Applied Microbiology and Biotechnology, 142279 Obolensk, Russia.
Glyakina AV; Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Russia.; Institute of Mathematical Problems of Biology and Keldysh Institute of Applied Mathematics, Russian Academy of Sciences, 142290 Pushchino, Russia.
Fadeev RS; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, 142290 Pushchino, Russia.
Ermolaeva SA; Gamaleya Research Centre of Epidemiology and Microbiology, 123098 Moscow, Russia.
Galzitskaya OV; Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Russia.; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, 142290 Pushchino, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 04; Vol. 23 (1). Date of Electronic Publication: 2022 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Staphylococcus aureus*/drug effects
Antimicrobial Peptides/*pharmacology
Bacterial Proteins/*chemistry
Ribosomal Proteins/*chemistry
Amino Acid Sequence ; Amyloidogenic Proteins/chemistry ; Antimicrobial Cationic Peptides/chemical synthesis ; Antimicrobial Cationic Peptides/chemistry ; Antimicrobial Cationic Peptides/pharmacology ; Antimicrobial Peptides/chemical synthesis ; Antimicrobial Peptides/chemistry ; Cell Survival/drug effects ; Cell-Penetrating Peptides/chemical synthesis ; Cell-Penetrating Peptides/chemistry ; Cell-Penetrating Peptides/pharmacology ; Dose-Response Relationship, Drug ; Fibroblasts ; Humans ; Methicillin-Resistant Staphylococcus aureus/drug effects ; Microbial Sensitivity Tests ; Models, Molecular ; Protein Conformation ; Protein Interaction Domains and Motifs
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Proteolytic Profiling of Streptococcal Pyrogenic Exotoxin B (SpeB) by Complementary HPLC-MS Approaches.
Autorzy:
Blöchl C; Bioanalytical Research Labs, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Holzner C; Structural Biology, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Luciano M; Molecular Immunology & Signal Transduction, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.; Cancer Cluster Salzburg, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Bauer R; Molecular Immunology & Signal Transduction, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Horejs-Hoeck J; Molecular Immunology & Signal Transduction, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.; Cancer Cluster Salzburg, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Eckhard U; Structural Biology, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.; Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona Science Park, Baldiri Reixac, 15-21, 08028 Barcelona, Spain.
Brandstetter H; Structural Biology, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.; Cancer Cluster Salzburg, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
Huber CG; Bioanalytical Research Labs, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.; Cancer Cluster Salzburg, Department of Biosciences, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 30; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 30.
Typ publikacji:
Journal Article
MeSH Terms:
Mass Spectrometry*
Proteolysis*
Bacterial Proteins/*metabolism
Exotoxins/*metabolism
Streptococcus pyogenes/*metabolism
Amino Acid Sequence ; Chromatography, High Pressure Liquid ; Escherichia coli/metabolism ; Humans ; Immunoglobulin G/chemistry ; Immunoglobulin G/metabolism ; Peptide Hydrolases/metabolism ; Peptides/metabolism ; Proteome/metabolism ; Recombinant Proteins/metabolism ; Substrate Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Caseinolytic Proteins (Clp) in the Genus Klebsiella : Special Focus on ClpK.
Autorzy:
Motiwala T; Department of Biochemistry, School of Life Sciences, Pietermaritzburg Campus, University of Kwa-Zulu Natal, Pietermaritzburg, Scottsville 3209, South Africa.
Akumadu BO; Protein Structure-Function Research Unit, School of Molecular and Cell Biology, University of the Witwatersrand, Johannesburg 2050, South Africa.
Zuma S; Department of Biochemistry, School of Life Sciences, Pietermaritzburg Campus, University of Kwa-Zulu Natal, Pietermaritzburg, Scottsville 3209, South Africa.
Mfeka MS; Department of Biochemistry, School of Life Sciences, Pietermaritzburg Campus, University of Kwa-Zulu Natal, Pietermaritzburg, Scottsville 3209, South Africa.
Chen W; College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Achilonu I; Protein Structure-Function Research Unit, School of Molecular and Cell Biology, University of the Witwatersrand, Johannesburg 2050, South Africa.
Syed K; Department of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.
Khoza T; Department of Biochemistry, School of Life Sciences, Pietermaritzburg Campus, University of Kwa-Zulu Natal, Pietermaritzburg, Scottsville 3209, South Africa.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Dec 29; Vol. 27 (1). Date of Electronic Publication: 2021 Dec 29.
Typ publikacji:
Journal Article
MeSH Terms:
Bacterial Proteins/*metabolism
Klebsiella/*metabolism
Adenosine Triphosphatases/metabolism ; Amino Acid Sequence ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Bacterial Proteins/isolation & purification ; Chemical Phenomena ; Klebsiella/classification ; Klebsiella/genetics ; Microbial Viability ; Models, Molecular ; Phylogeny ; Protein Conformation ; Protein Interaction Domains and Motifs ; Protein Processing, Post-Translational ; Protein Subunits ; Stress, Physiological ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structural and functional insights into the first Bacillus thuringiensis vegetative insecticidal protein of the Vpb4 fold, active against western corn rootworm.
Autorzy:
Kouadio JL; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Zheng M; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Aikins M; Department of Entomology, Kansas State University, Manhattan, Kansas, United States of America.
Duda D; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Duff S; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Chen D; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Zhang J; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Milligan J; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Taylor C; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Mamanella P; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Rydel T; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Kessenich C; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Panosian T; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Yin Y; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Moar W; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Giddings K; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Park Y; Department of Entomology, Kansas State University, Manhattan, Kansas, United States of America.
Jerga A; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Haas J; Bayer Crop Science, Chesterfield, Missouri, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Dec 20; Vol. 16 (12), pp. e0260532. Date of Electronic Publication: 2021 Dec 20 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacillus thuringiensis/*metabolism
Bacterial Proteins/*chemistry
Insecticides/*pharmacology
Amino Acid Sequence ; Animals ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Coleoptera/drug effects ; Coleoptera/growth & development ; Crystallography, X-Ray ; Insecticides/chemistry ; Intestines/metabolism ; Larva/drug effects ; Larva/metabolism ; Mutagenesis, Site-Directed ; Protein Multimerization ; Protein Structure, Tertiary ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/pharmacology ; Zea mays/metabolism ; Zea mays/parasitology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Comparative Study on Nickel Binding to Hpn-like Polypeptides from Two Helicobacter pylori Strains.
Autorzy:
Witkowska D; Institute of Health Sciences, University of Opole, Katowicka 68, 45-060 Opole, Poland.
Szebesczyk A; Institute of Health Sciences, University of Opole, Katowicka 68, 45-060 Opole, Poland.
Wątły J; Faculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
Braczkowski M; Institute of Medical Sciences, University of Opole, Oleska 48, 45-052 Opole, Poland.
Rowińska-Żyrek M; Faculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 08; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 08.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Bacterial Proteins/*metabolism
Helicobacter pylori/*classification
Nickel/*metabolism
Peptides/*metabolism
Amino Acid Sequence ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Calorimetry ; Glutamine/metabolism ; Helicobacter pylori/genetics ; Helicobacter pylori/metabolism ; Histidine/metabolism ; Potentiometry ; Protein Domains
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The FUR-like regulators PerRA and PerRB integrate a complex regulatory network that promotes mammalian host-adaptation and virulence of Leptospira interrogans.
Autorzy:
Grassmann AA; Department of Medicine, University of Connecticut Health, Farmington, Connecticut, United States of America.
Zavala-Alvarado C; Unité de Biologie des Spirochètes, Department of Microbiology, Institut Pasteur, Paris, France.; Université de Paris, Sorbonne Paris Cité, Communauté d'universités et d'établissements (COMUE), Bio Sorbonne Paris Cité (BioSPC), Paris, France.
Bettin EB; Department of Medicine, University of Connecticut Health, Farmington, Connecticut, United States of America.; Programa de Pós-Graduação em Biotecnologia, Centro de Desenvolvimento Tecnológico, Universidade Federal de Pelotas, Pelotas, Rio Grande do Sol, Brazil.
Picardeau M; Unité de Biologie des Spirochètes, Department of Microbiology, Institut Pasteur, Paris, France.
Benaroudj N; Unité de Biologie des Spirochètes, Department of Microbiology, Institut Pasteur, Paris, France.
Caimano MJ; Department of Medicine, University of Connecticut Health, Farmington, Connecticut, United States of America.; Department of Pediatrics, University of Connecticut Health, Farmington, Connecticut, United States of America.; Department of Molecular Biology and Biophysics, University of Connecticut Health, Farmington, Connecticut, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2021 Dec 02; Vol. 17 (12), pp. e1009078. Date of Electronic Publication: 2021 Dec 02 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacterial Proteins/*metabolism
Gene Regulatory Networks/*genetics
Host Adaptation/*genetics
Leptospira interrogans/*genetics
Leptospirosis/*microbiology
Amino Acid Sequence ; Animals ; Bacterial Proteins/genetics ; Gene Expression Regulation, Bacterial ; Humans ; Leptospira interrogans/pathogenicity ; Leptospira interrogans/physiology ; Mammals ; Mutation ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Sequence Alignment ; Virulence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The oxidative stress response of pathogenic Leptospira is controlled by two peroxide stress regulators which putatively cooperate in controlling virulence.
Autorzy:
Zavala-Alvarado C; Institut Pasteur, Université de Paris, Biologie des Spirochètes, F-75015 Paris, France.; Université de Paris, Sorbonne Paris Cité, F-75015 Paris, France.
G Huete S; Institut Pasteur, Université de Paris, Biologie des Spirochètes, F-75015 Paris, France.; Université de Paris, Sorbonne Paris Cité, F-75015 Paris, France.
Vincent AT; INRS-Centre Armand-Frappier, Bacterial Symbionts Evolution, Laval, Québec, Canada.
Sismeiro O; Institut Pasteur, Université de Paris, Biomics Transcriptome et Epigenome, F-75015 Paris, France.
Legendre R; Institut Pasteur, Université de Paris, Biomics Transcriptome et Epigenome, F-75015 Paris, France.; Institut Pasteur, Université de Paris, Hub Bioinformatique et Biostatistique, F-75015 Paris, France.
Varet H; Institut Pasteur, Université de Paris, Biomics Transcriptome et Epigenome, F-75015 Paris, France.; Institut Pasteur, Université de Paris, Hub Bioinformatique et Biostatistique, F-75015 Paris, France.
Bussotti G; Institut Pasteur, Université de Paris, Hub Bioinformatique et Biostatistique, F-75015 Paris, France.
Lorioux C; Institut Pasteur, Université de Paris, Biologie des Spirochètes, F-75015 Paris, France.
Lechat P; Institut Pasteur, Université de Paris, Hub Bioinformatique et Biostatistique, F-75015 Paris, France.
Coppée JY; Institut Pasteur, Université de Paris, Biomics Transcriptome et Epigenome, F-75015 Paris, France.
Veyrier FJ; INRS-Centre Armand-Frappier, Bacterial Symbionts Evolution, Laval, Québec, Canada.
Picardeau M; Institut Pasteur, Université de Paris, Biologie des Spirochètes, F-75015 Paris, France.
Benaroudj N; Institut Pasteur, Université de Paris, Biologie des Spirochètes, F-75015 Paris, France.
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Źródło:
PLoS pathogens [PLoS Pathog] 2021 Dec 02; Vol. 17 (12), pp. e1009087. Date of Electronic Publication: 2021 Dec 02 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacterial Proteins/*metabolism
Gene Regulatory Networks/*genetics
Leptospira/*genetics
Leptospirosis/*microbiology
Adaptation, Physiological ; Amino Acid Sequence ; Bacterial Proteins/genetics ; Gene Expression Regulation, Bacterial ; Leptospira/pathogenicity ; Leptospira/physiology ; Models, Molecular ; Mutation ; Oxidative Stress ; Phylogeny ; Regulon/genetics ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Sequence Alignment ; Virulence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Structural and biochemical analyses of the tetrameric carboxypeptidase S9Cfn from Fusobacterium nucleatum.
Autorzy:
Wang X; Department of Stomatology, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230601, People's Republic of China.
Cheng MT; Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, People's Republic of China.
Chen ZP; Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, People's Republic of China.
Jiang YL; Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, People's Republic of China.
Ge YS; Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, People's Republic of China.
Xia R; Department of Stomatology, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230601, People's Republic of China.
Hou WT; Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, People's Republic of China.
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Źródło:
Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2021 Dec 01; Vol. 77 (Pt 12), pp. 1554-1563. Date of Electronic Publication: 2021 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Bacterial Proteins/*metabolism
Carboxypeptidases/*metabolism
Fusobacterium nucleatum/*enzymology
Amino Acid Sequence ; Bacterial Proteins/chemistry ; Carboxypeptidases/chemistry ; Carboxypeptidases/genetics ; Catalytic Domain ; Crystallography, X-Ray ; Humans ; Mass Spectrometry ; Mutagenesis, Site-Directed ; Protein Conformation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Berberine Derivatives as Pseudomonas aeruginosa MexXY-OprM Inhibitors: Activity and In Silico Insights.
Autorzy:
Giorgini G; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Mangiaterra G; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Cedraro N; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Laudadio E; Department of Materials, Environmental Sciences and Urban Planning, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Sabbatini G; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Cantarini M; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Minnelli C; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Mobbili G; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Frangipani E; Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Biavasco F; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Galeazzi R; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Nov 02; Vol. 26 (21). Date of Electronic Publication: 2021 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Bacterial Agents/*chemistry
Anti-Bacterial Agents/*pharmacology
Bacterial Proteins/*antagonists & inhibitors
Bacterial Proteins/*chemistry
Berberine/*chemistry
Berberine/*pharmacology
Pseudomonas aeruginosa/*drug effects
Amino Acid Sequence ; Bacterial Proteins/genetics ; Berberine/analogs & derivatives ; Binding Sites ; Chemistry Techniques, Synthetic ; Drug Synergism ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Polymorphism, Genetic ; Protein Binding ; Pseudomonas aeruginosa/genetics ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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