Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""AMYOTROPHIC lateral sclerosis"" wg kryterium: Temat


Tytuł :
Palliative care, evidence, and ALS: The baby and the bathwater.
Autorzy :
Gordon JM; From the Department of Neurology, University of Washington, Seattle. .
Creutzfeldt CJ; From the Department of Neurology, University of Washington, Seattle.
Pokaż więcej
Źródło :
Neurology [Neurology] 2020 Oct 27; Vol. 95 (17), pp. 765-766. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Amyotrophic Lateral Sclerosis*/diagnosis
Amyotrophic Lateral Sclerosis*/therapy
Ambulatory Care ; Humans ; Outpatients ; Palliative Care
SCR Disease Name :
Amyotrophic Lateral Sclerosis 2, Juvenile
Opinia redakcyjna
Tytuł :
Selective degeneration of amygdalar nuclei in amyotrophic lateral sclerosis.
Autorzy :
Trojsi F; Department of Advanced Medical and Surgical Sciences, First Division of Neurology, University of Campania 'Luigi Vanvitelli', Naples, Italy. Electronic address: .
Siciliano M; Department of Advanced Medical and Surgical Sciences, First Division of Neurology, University of Campania 'Luigi Vanvitelli', Naples, Italy.
Tedeschi G; Department of Advanced Medical and Surgical Sciences, First Division of Neurology, University of Campania 'Luigi Vanvitelli', Naples, Italy.
Pokaż więcej
Źródło :
Journal of the neurological sciences [J Neurol Sci] 2020 Oct 15; Vol. 417, pp. 117038. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Amyotrophic Lateral Sclerosis*
Motor Neuron Disease*
Amygdala ; Humans
Opinia redakcyjna
Tytuł :
Quality-control mechanisms targeting translationally stalled and C-terminally extended poly(GR) associated with ALS/FTD.
Autorzy :
Li S; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305.
Wu Z; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305.
Tantray I; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305.
Li Y; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305.
Chen S; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305.
Dong J; Electrical Engineering and Computer Sciences, University of California, Berkeley, CA 94305.
Glynn S; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794.
Vogel H; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305.
Snyder M; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305.
Lu B; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305; .
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Oct 06; Vol. 117 (40), pp. 25104-25115. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
ATPases Associated with Diverse Cellular Activities/*genetics
Amyotrophic Lateral Sclerosis/*genetics
C9orf72 Protein/*genetics
Drosophila Proteins/*genetics
Frontotemporal Dementia/*genetics
Metalloendopeptidases/*genetics
Mitochondrial Proteins/*genetics
Proteome/*genetics
Receptors, Notch/*genetics
Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/pathology ; Animals ; Arginine/genetics ; DNA Repeat Expansion/genetics ; Disease Models, Animal ; Drosophila melanogaster/genetics ; Frontotemporal Dementia/metabolism ; Frontotemporal Dementia/pathology ; HEK293 Cells ; Humans ; Mitochondria/genetics ; Mitochondria/metabolism ; Mitochondria/pathology ; Protein Biosynthesis ; Ribosomes/genetics ; Ribosomes/metabolism ; Signal Transduction/genetics
SCR Disease Name :
Frontotemporal Dementia With Motor Neuron Disease
Czasopismo naukowe
Tytuł :
Systematic microsatellite repeat expansion cloning and validation.
Autorzy :
Rohilla KJ; Department of Biochemistry and Molecular Biology, School of Medicine, Southern Illinois University, Carbondale, USA.
Ovington KN; Department of Biochemistry and Molecular Biology, School of Medicine, Southern Illinois University, Carbondale, USA.
Pater AA; Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, USA.
Barton M; Department of Biochemistry and Molecular Biology, School of Medicine, Southern Illinois University, Carbondale, USA.
Henke AJ; Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, USA.
Gagnon KT; Department of Biochemistry and Molecular Biology, School of Medicine, Southern Illinois University, Carbondale, USA. .; Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, USA. .
Pokaż więcej
Źródło :
Human genetics [Hum Genet] 2020 Oct; Vol. 139 (10), pp. 1233-1246. Date of Electronic Publication: 2020 Apr 10.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Repeat Expansion*
Microsatellite Repeats*
Amyotrophic Lateral Sclerosis/*genetics
C9orf72 Protein/*genetics
Cloning, Molecular/*methods
Frontotemporal Dementia/*genetics
Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/pathology ; Base Sequence ; C9orf72 Protein/metabolism ; DNA Restriction Enzymes/chemistry ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Frontotemporal Dementia/metabolism ; Frontotemporal Dementia/pathology ; Gene Expression ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; Genome, Human ; Genotype ; High-Throughput Nucleotide Sequencing ; Humans ; Polymerase Chain Reaction/methods ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism
Czasopismo naukowe
Tytuł :
Identifying putative cerebrospinal fluid biomarkers of amyotrophic lateral sclerosis in a north Indian population.
Autorzy :
Khosla R; Neuroscience Research Lab, PGIMER, Chandigarh, India.
Rain M; Neuroscience Research Lab, PGIMER, Chandigarh, India.
Chawathey S; D. Y. Patil University School of Medicine, Navi Mumbai, India.
Modgil S; Neuroscience Research Lab, PGIMER, Chandigarh, India.
Tyagi R; Neuroscience Research Lab, PGIMER, Chandigarh, India.
Thakur K; Neuroscience Research Lab, PGIMER, Chandigarh, India.
Pannu V; Government Medical College and Hospital, Chandigarh, India.
Sharma SK; Department of Statistics, Panjab University, Chandigarh, India.
Anand A; Neuroscience Research Lab, PGIMER, Chandigarh, India.
Pokaż więcej
Źródło :
Muscle & nerve [Muscle Nerve] 2020 Oct; Vol. 62 (4), pp. 528-533. Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amyotrophic Lateral Sclerosis/*diagnosis
Cell Cycle Proteins/*cerebrospinal fluid
Chemokine CCL2/*cerebrospinal fluid
DNA-Binding Proteins/*cerebrospinal fluid
Membrane Transport Proteins/*cerebrospinal fluid
Ribonuclease, Pancreatic/*cerebrospinal fluid
Vascular Endothelial Growth Factor A/*cerebrospinal fluid
Vascular Endothelial Growth Factor Receptor-2/*cerebrospinal fluid
Adult ; Amyotrophic Lateral Sclerosis/cerebrospinal fluid ; Biomarkers/cerebrospinal fluid ; Case-Control Studies ; Female ; Humans ; India ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
[Triad TMS of Human Motor Cortex].
Autorzy :
Hanajima R; Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University.
Ugawa Y
Pokaż więcej
Źródło :
Brain and nerve = Shinkei kenkyu no shinpo [Brain Nerve] 2020 Nov; Vol. 72 (11), pp. 1247-1253.
Typ publikacji :
Journal Article
MeSH Terms :
Amyotrophic Lateral Sclerosis*
Motor Cortex*
Parkinson Disease*
Electromyography ; Evoked Potentials, Motor ; Humans ; Transcranial Magnetic Stimulation
Czasopismo naukowe
Tytuł :
Selective neuronal degeneration in MATR3 S85C knock-in mouse model of early-stage ALS.
Autorzy :
Kao CS; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
van Bruggen R; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.
Kim JR; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Chen XXL; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Chan C; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Lee J; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.
Cho WI; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.
Zhao M; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Arndt C; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.
Maksimovic K; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Khan M; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Tan Q; Department of Cell Biology, University of Alberta, Edmonton, AB, Canada.
Wilson MD; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Park J; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada. .; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2020 Oct 20; Vol. 11 (1), pp. 5304. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amyotrophic Lateral Sclerosis/*metabolism
Motor Neurons/*metabolism
Nuclear Matrix-Associated Proteins/*genetics
Nuclear Matrix-Associated Proteins/*metabolism
RNA-Binding Proteins/*genetics
RNA-Binding Proteins/*metabolism
Amyotrophic Lateral Sclerosis/genetics ; Animals ; Disease Models, Animal ; Female ; Gene Knock-In Techniques ; Humans ; Loss of Function Mutation ; Male ; Mice ; Mutation, Missense ; Purkinje Cells/metabolism
Czasopismo naukowe
Tytuł :
Application of muscle ultrasound for the evaluation of patients with amyotrophic lateral sclerosis: An observational cross-sectional study.
Autorzy :
Rajabkhah S; Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Jalal al Ahmad, Tehran, 1411713135, Iran.
Moradi K; Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Jalal al Ahmad, Tehran, 1411713135, Iran.
Okhovat AA; Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Jalal al Ahmad, Tehran, 1411713135, Iran.; Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Van Alfen N; Department of Neurology and Clinical Neurophysiology, Radboud University Medical Center, Donders Institute for Brain Cognition and Behaviour, Nijmegen, The Netherlands.
Fathi D; Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Jalal al Ahmad, Tehran, 1411713135, Iran.; Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Aghaghazvini L; Department of Radiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ashraf-Ganjouei A; Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Jalal al Ahmad, Tehran, 1411713135, Iran.
Attarian S; Neuromuscular Disease and ALS Reference Center, Timone University Hospital Aix-Marseille University, Marseille, France.
Nafissi S; Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Jalal al Ahmad, Tehran, 1411713135, Iran.; Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Fatehi F; Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Jalal al Ahmad, Tehran, 1411713135, Iran.; Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Pokaż więcej
Źródło :
Muscle & nerve [Muscle Nerve] 2020 Oct; Vol. 62 (4), pp. 516-521. Date of Electronic Publication: 2020 Aug 14.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Amyotrophic Lateral Sclerosis/*diagnostic imaging
Motor Neurons/*physiology
Muscle, Skeletal/*diagnostic imaging
Adult ; Aged ; Amyotrophic Lateral Sclerosis/physiopathology ; Cross-Sectional Studies ; Electromyography ; Female ; Humans ; Male ; Middle Aged ; Muscle, Skeletal/physiopathology ; Ultrasonography
Czasopismo naukowe
Tytuł :
Reply to: Frequent self-assessments in ALS clinical trials: Worthwhile or an unnecessary burden?
Autorzy :
Rutkove SB; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Narayanaswami P; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Berisha V; Arizona State University, Phoenix, Arizona, USA.
Liss J; Arizona State University, Phoenix, Arizona, USA.
Hahn S; Arizona State University, Phoenix, Arizona, USA.
Shelton K; Barrow Neurological Clinic, Phoenix, Arizona, USA.
Qi K; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Pandeya S; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Shefner JM; Barrow Neurological Clinic, Phoenix, Arizona, USA.
Pokaż więcej
Źródło :
Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2020 Oct; Vol. 7 (10), pp. 2076-2077. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Letter; Comment
MeSH Terms :
Amyotrophic Lateral Sclerosis*/therapy
Self-Assessment*
Humans ; Proof of Concept Study
SCR Disease Name :
Amyotrophic Lateral Sclerosis 2, Juvenile
Opinia redakcyjna
Tytuł :
Frequent self-assessments in ALS Clinical Trials: worthwhile or an unnecessary burden for patients?
Autorzy :
van Eijk RPA; Department of Neurology, UMC Utrecht Brain Centre, University Medical Centre Utrecht, Utrecht, the Netherlands.; Biostatistics and Research Support, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, the Netherlands.
Pokaż więcej
Źródło :
Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2020 Oct; Vol. 7 (10), pp. 2074-2075. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Letter; Comment
MeSH Terms :
Amyotrophic Lateral Sclerosis*/diagnosis
Self-Assessment*
Humans ; Proof of Concept Study ; Quality of Life
SCR Disease Name :
Amyotrophic Lateral Sclerosis 2, Juvenile
Opinia redakcyjna
Tytuł :
Addressing heterogeneity in amyotrophic lateral sclerosis CLINICAL TRIALS.
Autorzy :
Goyal NA; University of California, Irvine, California.
Berry JD; Healey Center at Massachusetts General Hospital, Boston, Massachusetts.
Windebank A; Mayo Clinic, Rochester, Minnesota.
Staff NP; Mayo Clinic, Rochester, Minnesota.
Maragakis NJ; Johns Hopkins University, Baltimore, Maryland.
van den Berg LH; University Medical Center Utrecht, Utrecht, The Netherlands.
Genge A; Montreal Neurological Institute and Hospital, Montreal, Quebec, Canada.
Miller R; California Pacific Medical Center, San Francisco, California.
Baloh RH; Robert H. Baloh, Cedars-Sinai Medical Center, California, Los Angeles.
Kern R; Brainstorm Cell Therapeutics, New York, New York.
Gothelf Y; Brainstorm Cell Therapeutics, New York, New York.
Lebovits C; Brainstorm Cell Therapeutics, New York, New York.
Cudkowicz M; Healey Center at Massachusetts General Hospital, Boston, Massachusetts.
Pokaż więcej
Źródło :
Muscle & nerve [Muscle Nerve] 2020 Aug; Vol. 62 (2), pp. 156-166. Date of Electronic Publication: 2020 Jan 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biological Variation, Population*
Biomarkers*
Outcome Assessment, Health Care*
Amyotrophic Lateral Sclerosis/*drug therapy
Clinical Trials as Topic/*methods
Amyotrophic Lateral Sclerosis/genetics ; Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/physiopathology ; Disease Progression ; Drug Development ; Humans ; Muscle Strength ; Physical Functional Performance ; Precision Medicine ; Prognosis ; Reproducibility of Results ; Respiratory Function Tests ; Risk Assessment ; Speech ; Transcranial Magnetic Stimulation
Czasopismo naukowe
Tytuł :
Hypothesis: amyotrophic lateral sclerosis and environmental pollutants.
Autorzy :
Swash M; Barts and The London School of Medicine, Queen Mary University of London and Royal London Hospital, London, UK.; Institute of Neuroscience, University of Lisbon, Lisbon, Portugal.
Eisen A; Division of Neurology, University of British Columbia, Vancouver, British Columbia, Canada.
Pokaż więcej
Źródło :
Muscle & nerve [Muscle Nerve] 2020 Aug; Vol. 62 (2), pp. 187-191. Date of Electronic Publication: 2020 Mar 16.
Typ publikacji :
Historical Article; Journal Article
MeSH Terms :
Environmental Pollutants*
Gene-Environment Interaction*
Life Expectancy*
Amyotrophic Lateral Sclerosis/*epidemiology
Environmental Exposure/*statistics & numerical data
Industrial Development/*statistics & numerical data
Amyotrophic Lateral Sclerosis/genetics ; Amyotrophic Lateral Sclerosis/history ; C9orf72 Protein/genetics ; Causality ; DNA-Binding Proteins/genetics ; Environmental Exposure/history ; History, 19th Century ; History, 20th Century ; History, 21st Century ; Humans ; Incidence ; Industrial Development/history ; Mutation ; Superoxide Dismutase-1/genetics
Czasopismo naukowe
Tytuł :
Lipocalin-2 is increased in amyotrophic lateral sclerosis.
Autorzy :
Petrozziello T; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts.
Mills AN; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts.
Farhan SMK; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Mueller KA; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts.
Granucci EJ; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts.
Glajch KE; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts.
Chan J; Biostatistics Center, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Chew S; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts.
Berry JD; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts.
Sadri-Vakili G; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts.
Pokaż więcej
Źródło :
Muscle & nerve [Muscle Nerve] 2020 Aug; Vol. 62 (2), pp. 272-283. Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Amyotrophic Lateral Sclerosis/*genetics
Inflammation/*metabolism
Lipocalin-2/*genetics
Motor Cortex/*metabolism
Spinal Cord/*metabolism
Adult ; Aged ; Aged, 80 and over ; Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/physiopathology ; Blotting, Western ; Case-Control Studies ; Cell Death ; Cell Line, Tumor ; Cytokines/drug effects ; Cytokines/metabolism ; Enzyme-Linked Immunosorbent Assay ; Female ; Fluorescent Antibody Technique ; Humans ; In Vitro Techniques ; Lipocalin-2/antagonists & inhibitors ; Lipocalin-2/metabolism ; Lipocalin-2/pharmacology ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Living near waterbodies as a proxy of cyanobacteria exposure and risk of amyotrophic lateral sclerosis: a population based case-control study.
Autorzy :
Fiore M; Department of Medical, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123; Environmental and Food Hygiene Laboratory (LIAA). Department 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123. Electronic address: .
Parisio R; Department of Medical, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123.
Filippini T; CREAGEN - Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Mantione V; Department of Medical, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123.
Platania A; Department of Medical, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123.
Odone A; Department of Biomedical, Biotechnological, and Translational Sciences, University of Parma, 14 Via Gramsci, 43126, Parma, Italy.
Signorelli C; Department of Biomedical, Biotechnological, and Translational Sciences, University of Parma, 14 Via Gramsci, 43126, Parma, Italy; School of Medicine, University Vita-Salute San Raffaele, 58 Via Olgettina Milano, 20132, Milan, Italy.
Pietrini V; Department of Neuroscience, Neurology Unit, University of Parma, 14 Via Gramsci, 43126, Parma, Italy.
Mandrioli J; Department of Neuroscience, S. Agostino-Estense Hospital, and University of Modena and Reggio Emilia, 1355 Via Pietro Giardini, 41126, Modena, Italy.
Teggi S; Department of Engineering 'Enzo Ferrari', University of Modena and Reggio Emilia, 10 Via Vivarelli, 41125, Modena, Italy.
Costanzini S; Department of Engineering 'Enzo Ferrari', University of Modena and Reggio Emilia, 10 Via Vivarelli, 41125, Modena, Italy.
Antonio C; Department of Medical, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123; Environmental and Food Hygiene Laboratory (LIAA). Department 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123.
Zuccarello P; Department of Medical, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123; Environmental and Food Hygiene Laboratory (LIAA). Department 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123.
Oliveri Conti G; Department of Medical, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123; Environmental and Food Hygiene Laboratory (LIAA). Department 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123. Electronic address: .
Nicoletti A; Section of Neurosciences, Department 'G.F. Ingrassia', University of Catania, Catania, Italy.
Zappia M; Section of Neurosciences, Department 'G.F. Ingrassia', University of Catania, Catania, Italy.
Vinceti M; CREAGEN - Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy; Department of Epidemiology, Boston University School of Public Health, Boston, MA, United States.
Ferrante M; Department of Medical, Surgical and Advanced Technologies 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123; Environmental and Food Hygiene Laboratory (LIAA). Department 'G.F. Ingrassia', University of Catania, Catania, Italy, Via Santa Sofia, 87, 95123.
Pokaż więcej
Źródło :
Environmental research [Environ Res] 2020 Jul; Vol. 186, pp. 109530. Date of Electronic Publication: 2020 Apr 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amyotrophic Lateral Sclerosis*/chemically induced
Amyotrophic Lateral Sclerosis*/epidemiology
Cyanobacteria*
Neurodegenerative Diseases*
Case-Control Studies ; Humans ; Italy/epidemiology ; Risk Factors
Czasopismo naukowe
Tytuł :
Oligodendrocyte pathology exceeds axonal pathology in white matter in human amyotrophic lateral sclerosis.
Autorzy :
Lorente Pons A; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.; School of Biochemistry, University of Bristol, Bristol, UK.
Higginbottom A; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.
Cooper-Knock J; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.
Alrafiah A; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.; Medical Laboratory Technology Department, Faculty of Applied Medical Sciences, Medical School, King AbdulAziz University, Jeddah, Saudi Arabia.
Alofi E; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.; Department of Physiology, Faculty of Medicine, Medical School, King AbdulAziz University, Jeddah, Saudi Arabia.
Kirby J; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.
Shaw PJ; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.
Wood JD; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.
Highley JR; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.
Pokaż więcej
Źródło :
The Journal of pathology [J Pathol] 2020 Jul; Vol. 251 (3), pp. 262-271. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amyotrophic Lateral Sclerosis/*pathology
Axons/*pathology
Oligodendroglia/*pathology
Pyramidal Tracts/*pathology
White Matter/*pathology
Amyotrophic Lateral Sclerosis/genetics ; Amyotrophic Lateral Sclerosis/metabolism ; Autopsy ; Axons/chemistry ; Biomarkers/analysis ; C9orf72 Protein/genetics ; Case-Control Studies ; DNA-Binding Proteins/analysis ; Genetic Predisposition to Disease ; Heterogeneous-Nuclear Ribonucleoprotein Group A-B/analysis ; Humans ; Mutation ; Myelin Basic Protein/analysis ; Oligodendroglia/chemistry ; Phenotype ; Pyramidal Tracts/chemistry ; RNA Transport ; RNA, Messenger/metabolism ; Sequestosome-1 Protein/analysis ; Transcription Factors/analysis ; White Matter/chemistry
Czasopismo naukowe
Tytuł :
Automated analysis of natural speech in amyotrophic lateral sclerosis spectrum disorders.
Autorzy :
Nevler N; From the Penn Frontotemporal Degeneration Center (N.N., S.A., C.M., D.J.I., M.G.), Department of Neurology (N.N., S.A., C.M., L.E., L.M., D.J.I., M.G.), and Linguistic Data Consortium (S.C., M.L.), Department of Linguistics, University of Pennsylvania, Philadelphia. .
Ash S; From the Penn Frontotemporal Degeneration Center (N.N., S.A., C.M., D.J.I., M.G.), Department of Neurology (N.N., S.A., C.M., L.E., L.M., D.J.I., M.G.), and Linguistic Data Consortium (S.C., M.L.), Department of Linguistics, University of Pennsylvania, Philadelphia.
McMillan C; From the Penn Frontotemporal Degeneration Center (N.N., S.A., C.M., D.J.I., M.G.), Department of Neurology (N.N., S.A., C.M., L.E., L.M., D.J.I., M.G.), and Linguistic Data Consortium (S.C., M.L.), Department of Linguistics, University of Pennsylvania, Philadelphia.
Elman L; From the Penn Frontotemporal Degeneration Center (N.N., S.A., C.M., D.J.I., M.G.), Department of Neurology (N.N., S.A., C.M., L.E., L.M., D.J.I., M.G.), and Linguistic Data Consortium (S.C., M.L.), Department of Linguistics, University of Pennsylvania, Philadelphia.
McCluskey L; From the Penn Frontotemporal Degeneration Center (N.N., S.A., C.M., D.J.I., M.G.), Department of Neurology (N.N., S.A., C.M., L.E., L.M., D.J.I., M.G.), and Linguistic Data Consortium (S.C., M.L.), Department of Linguistics, University of Pennsylvania, Philadelphia.
Irwin DJ; From the Penn Frontotemporal Degeneration Center (N.N., S.A., C.M., D.J.I., M.G.), Department of Neurology (N.N., S.A., C.M., L.E., L.M., D.J.I., M.G.), and Linguistic Data Consortium (S.C., M.L.), Department of Linguistics, University of Pennsylvania, Philadelphia.
Cho S; From the Penn Frontotemporal Degeneration Center (N.N., S.A., C.M., D.J.I., M.G.), Department of Neurology (N.N., S.A., C.M., L.E., L.M., D.J.I., M.G.), and Linguistic Data Consortium (S.C., M.L.), Department of Linguistics, University of Pennsylvania, Philadelphia.
Liberman M; From the Penn Frontotemporal Degeneration Center (N.N., S.A., C.M., D.J.I., M.G.), Department of Neurology (N.N., S.A., C.M., L.E., L.M., D.J.I., M.G.), and Linguistic Data Consortium (S.C., M.L.), Department of Linguistics, University of Pennsylvania, Philadelphia.
Grossman M; From the Penn Frontotemporal Degeneration Center (N.N., S.A., C.M., D.J.I., M.G.), Department of Neurology (N.N., S.A., C.M., L.E., L.M., D.J.I., M.G.), and Linguistic Data Consortium (S.C., M.L.), Department of Linguistics, University of Pennsylvania, Philadelphia. .
Pokaż więcej
Źródło :
Neurology [Neurology] 2020 Sep 22; Vol. 95 (12), pp. e1629-e1639. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Amyotrophic Lateral Sclerosis/*complications
Brain/*diagnostic imaging
Speech Disorders/*diagnostic imaging
Speech Production Measurement/*methods
Aged ; Amyotrophic Lateral Sclerosis/diagnostic imaging ; Amyotrophic Lateral Sclerosis/pathology ; Brain/pathology ; Female ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Neuroimaging/methods ; Speech Disorders/etiology ; Speech Disorders/pathology
Czasopismo naukowe
Tytuł :
Reply to Comment on "Environmental and Occupational Risk Factors of Amyotrophic Lateral Sclerosis: A Population-Based Case-Control Study".
Autorzy :
Filippini T; CREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Tesauro M; Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.
Fiore M; Department of Medical, Surgical Sciences and Advanced Technologies 'G. F. Ingrassia', Catania University, 95123 Catania, Italy.
Malagoli C; CREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Consonni M; Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.
Violi F; CREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.; Azienda USL-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.
Iacuzio L; CREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.; Department of Public Health, Local Health Unit, 41121 Modena, Italy.
Arcolin E; CREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Oliveri Conti G; Department of Medical, Surgical Sciences and Advanced Technologies 'G. F. Ingrassia', Catania University, 95123 Catania, Italy.
Cristaldi A; Department of Medical, Surgical Sciences and Advanced Technologies 'G. F. Ingrassia', Catania University, 95123 Catania, Italy.
Zuccarello P; Department of Medical, Surgical Sciences and Advanced Technologies 'G. F. Ingrassia', Catania University, 95123 Catania, Italy.
Zucchi E; Neurology Unit, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Mazzini L; ALS Centre Department of Neurology, 'Maggiore della Carità' University Hospital, 28100 Novara, Italy.
Pisano F; Neurological Rehabilitation Division, Policlinico San Marco di Zingonia, 24046 Zingonia (BG), Italy.
Gagliardi I; ALS Centre Department of Neurology, 'Maggiore della Carità' University Hospital, 28100 Novara, Italy.
Patti F; Department of Medical, Surgical Sciences and Advanced Technologies 'G. F. Ingrassia', Catania University, 95123 Catania, Italy.
Mandrioli J; Neurology Unit, Department of Neuroscience, S. Agostino Estense Hospital, Azienda Ospedaliero Universitaria di Modena, 41126 Modena, Italy.
Ferrante M; Department of Medical, Surgical Sciences and Advanced Technologies 'G. F. Ingrassia', Catania University, 95123 Catania, Italy.
Vinceti M; CREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.; Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA.
Pokaż więcej
Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2020 Sep 07; Vol. 17 (18). Date of Electronic Publication: 2020 Sep 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Amyotrophic Lateral Sclerosis*/chemically induced
Amyotrophic Lateral Sclerosis*/epidemiology
Occupational Exposure*/adverse effects
Case-Control Studies ; Humans ; Research Design ; Risk Factors
Czasopismo naukowe
Tytuł :
Evolution of a Human-Specific Tandem Repeat Associated with ALS.
Autorzy :
Course MM; Division of Medical Genetics, University of Washington School of Medicine, Seattle, WA 98195, USA.
Gudsnuk K; Division of Medical Genetics, University of Washington School of Medicine, Seattle, WA 98195, USA.
Smukowski SN; Division of Medical Genetics, University of Washington School of Medicine, Seattle, WA 98195, USA.
Winston K; Division of Medical Genetics, University of Washington School of Medicine, Seattle, WA 98195, USA.
Desai N; Division of Medical Genetics, University of Washington School of Medicine, Seattle, WA 98195, USA.
Ross JP; Montreal Neurological Institute and Hospital, McGill University, Montreal, QC H3A 2B4, Canada; Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada.
Sulovari A; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.
Bourassa CV; Montreal Neurological Institute and Hospital, McGill University, Montreal, QC H3A 2B4, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada.
Spiegelman D; Montreal Neurological Institute and Hospital, McGill University, Montreal, QC H3A 2B4, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada.
Couthouis J; Department of Genetics, Stanford University, Stanford, CA 94305, USA.
Yu CE; Geriatric Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, WA 98108, USA.
Tsuang DW; Geriatric Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, WA 98108, USA.
Jayadev S; Division of Medical Genetics, University of Washington School of Medicine, Seattle, WA 98195, USA; Department of Neurology, University of Washington School of Medicine, Seattle, WA 98195, USA.
Kay MA; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Department of Pediatrics, Stanford University, Stanford, CA 94305, USA.
Gitler AD; Department of Genetics, Stanford University, Stanford, CA 94305, USA.
Dupre N; Neuroscience Axis, CHU de Québec-Université Laval & Department of Medicine, Université Laval, Quebec City, QC G1J 1Z4, Canada.
Eichler EE; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.
Dion PA; Montreal Neurological Institute and Hospital, McGill University, Montreal, QC H3A 2B4, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada.
Rouleau GA; Montreal Neurological Institute and Hospital, McGill University, Montreal, QC H3A 2B4, Canada; Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 2B4, Canada.
Valdmanis PN; Division of Medical Genetics, University of Washington School of Medicine, Seattle, WA 98195, USA; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA. Electronic address: .
Pokaż więcej
Źródło :
American journal of human genetics [Am J Hum Genet] 2020 Sep 03; Vol. 107 (3), pp. 445-460. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Evolution, Molecular*
Adaptor Proteins, Signal Transducing/*genetics
Amyotrophic Lateral Sclerosis/*genetics
Tandem Repeat Sequences/*genetics
Aged ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Amyotrophic Lateral Sclerosis/pathology ; DNA Repeat Expansion/genetics ; Female ; Gene Expression Regulation/genetics ; Humans ; Male ; Minisatellite Repeats/genetics ; Phenotype ; Species Specificity
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies