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Wyświetlanie 1-20 z 78
Tytuł:
Evaluation of Pharmacokinetics and Safety With Bioequivalence of Anastrozole in Healthy Chinese Volunteers: Bioequivalence Study Findings.
Autorzy:
Wang Y; Phase I Clinical Research Center, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China.
Wang T; Intensive Care Unit, Shaanxi Traditional Chinese Medicine Hospital, Xi'an, China.
Fang H; Department of Laboratory Medicine, Taizhou First People's Hospital, Taizhou, Zhejiang, China.
Huang H; Department of Laboratory Medicine, Quzhou People's Hospital, Quzhou, Zhejiang, China.
Fang L; Department of Laboratory Medicine, Hangzhou Ninth People's Hospital, Hangzhou, Zhejiang, China.
Zhang X; Intensive Care Unit, Shaanxi Traditional Chinese Medicine Hospital, Xi'an, China.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2022 Jun; Vol. 11 (6), pp. 687-694. Date of Electronic Publication: 2022 Apr 29.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Therapeutic Equivalency*
Anastrozole/adverse effects ; China ; Chromatography, Liquid ; Cross-Over Studies ; Female ; Humans ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CDK4/6 and PI3K inhibitors: A new promise for patients with HER2-positive breast cancer.
Autorzy:
Agostinetto E; Academic Trials Promoting Team, Institut Jules Bordet and l'Université Libre de Bruxelles (U.L.B), Brussels, Belgium.; Humanitas Clinical and Research Center - IRCCS, Humanitas Cancer Center, Milan, Italy.
Debien V; Academic Trials Promoting Team, Institut Jules Bordet and l'Université Libre de Bruxelles (U.L.B), Brussels, Belgium.
Marta GN; Academic Trials Promoting Team, Institut Jules Bordet and l'Université Libre de Bruxelles (U.L.B), Brussels, Belgium.
Lambertini M; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genova, Italy.; Department of Medical Oncology, U.O.C Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Piccart-Gebhart M; Oncology Department, Institut Jules Bordet, Brussels, Belgium.
de Azambuja E; Academic Trials Promoting Team, Institut Jules Bordet and l'Université Libre de Bruxelles (U.L.B), Brussels, Belgium.
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Źródło:
European journal of clinical investigation [Eur J Clin Invest] 2021 Jul; Vol. 51 (7), pp. e13535. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Breast Neoplasms/*drug therapy
Cyclin-Dependent Kinase 4/*antagonists & inhibitors
Cyclin-Dependent Kinase 6/*antagonists & inhibitors
Phosphoinositide-3 Kinase Inhibitors/*therapeutic use
Protein Kinase Inhibitors/*therapeutic use
Receptor, ErbB-2/*metabolism
Aminopyridines/therapeutic use ; Anastrozole/therapeutic use ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antineoplastic Agents, Hormonal/therapeutic use ; Antineoplastic Agents, Immunological/therapeutic use ; Benzimidazoles/therapeutic use ; Breast Neoplasms/metabolism ; Female ; Fulvestrant/therapeutic use ; Humans ; Letrozole/therapeutic use ; Piperazines/therapeutic use ; Purines/therapeutic use ; Pyridines/therapeutic use ; Receptors, Estrogen/metabolism ; Receptors, Progesterone/metabolism ; Tamoxifen/therapeutic use ; Trastuzumab/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Bioequivalence of Oral Formulations of Anastrozole in Healthy Chinese Male Volunteers: A Randomized, Single-Dose, Two-Period, Two-Sequence Crossover Study.
Autorzy:
Chen J; Laboratory of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
Zhuang J; Laboratory of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
Wu J; The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Chen X; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Wang X; Laboratory of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
Huang L; Laboratory of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
Zeng G; Laboratory of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
Chen J; The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Liao X; The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Chen X; The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Ma Z; The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Zhong G; Laboratory of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
Huang M; Laboratory of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
Zhong D; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Zhao X; Laboratory of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2019 Feb; Vol. 8 (2), pp. 217-222. Date of Electronic Publication: 2018 Apr 16.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Anastrozole/*administration & dosage
Anastrozole/*pharmacokinetics
Drugs, Generic/*administration & dosage
Drugs, Generic/*pharmacokinetics
Administration, Oral ; Adult ; Area Under Curve ; Biological Availability ; China ; Chromatography, High Pressure Liquid ; Cross-Over Studies ; Healthy Volunteers ; Humans ; Male ; Tablets ; Tandem Mass Spectrometry ; Therapeutic Equivalency ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of Changes in the Lipid Profiles of Eastern Chinese Postmenopausal Women With Early-Stage Breast Cancer Treated With Different Aromatase Inhibitors: A Retrospective Study.
Autorzy:
Tian W; Department of Surgical Oncology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Wu M; Department of Surgical Oncology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Deng Y; Department of Surgical Oncology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2018 Nov; Vol. 7 (8), pp. 837-843. Date of Electronic Publication: 2017 Dec 29.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aromatase Inhibitors/*pharmacology
Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*blood
Breast Neoplasms/*drug therapy
Lipid Metabolism/*drug effects
Lipids/*blood
Postmenopause/*blood
Aged ; Anastrozole/pharmacology ; Anastrozole/therapeutic use ; Androstadienes/pharmacology ; Androstadienes/therapeutic use ; Asian People ; China ; Female ; Humans ; Letrozole/pharmacology ; Letrozole/therapeutic use ; Middle Aged ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hidden estrogen production from ovarian remnants leading to progression of disease in metastatic breast cancer.
Autorzy:
Weiner A; Montefiore Medical Center, Bronx, NY, USA.
D'Andrea GM; Memorial Sloan Kettering Cancer Center, New York, NY, USA.
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Źródło:
The breast journal [Breast J] 2018 Jul; Vol. 24 (4), pp. 642-643. Date of Electronic Publication: 2018 Jan 22.
Typ publikacji:
Case Reports
MeSH Terms:
Breast Neoplasms/*pathology
Breast Neoplasms/*surgery
Liver Neoplasms/*secondary
Ovariectomy/*adverse effects
Adult ; Anastrozole/therapeutic use ; Aromatase Inhibitors/therapeutic use ; Breast Neoplasms/drug therapy ; Estrogens/metabolism ; Female ; Humans ; Liver Neoplasms/diagnostic imaging ; Ovarian Diseases/surgery ; Positron Emission Tomography Computed Tomography ; Receptor, ErbB-2 ; Syndrome
Raport
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Extended Adjuvant Endocrine Therapy in Breast Cancer: Evidence and Update - A Review.
Autorzy:
Jinih M; Department of Academic Surgery, Cork University Hospital (CUH), National University of Ireland (Cork), Wilton, Cork, Ireland.
Relihan N; Department of Academic Surgery, Cork University Hospital (CUH), National University of Ireland (Cork), Wilton, Cork, Ireland.
Corrigan MA; Department of Academic Surgery, Cork University Hospital (CUH), National University of Ireland (Cork), Wilton, Cork, Ireland.
O'Reilly S; Department of Medical Oncology, Cork University Hospital (CUH), National University of Ireland (Cork), Wilton, Cork, Ireland.
Redmond HP; Department of Academic Surgery, Cork University Hospital (CUH), National University of Ireland (Cork), Wilton, Cork, Ireland.
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Źródło:
The breast journal [Breast J] 2017 Nov; Vol. 23 (6), pp. 694-705. Date of Electronic Publication: 2017 Mar 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antineoplastic Agents, Hormonal/*administration & dosage
Aromatase Inhibitors/*administration & dosage
Breast Neoplasms/*drug therapy
Neoplasm Recurrence, Local/*drug therapy
Nitriles/*administration & dosage
Tamoxifen/*administration & dosage
Triazoles/*administration & dosage
Anastrozole ; Chemotherapy, Adjuvant ; Clinical Trials as Topic ; Drug Administration Schedule ; Female ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Adjuvant aromatase inhibitor options in overweight and obese postmenopausal women with breast cancer.
Autorzy:
Chlebowski RT; Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California.
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Źródło:
The breast journal [Breast J] 2013 Sep-Oct; Vol. 19 (5), pp. 552-4. Date of Electronic Publication: 2013 Aug 14.
Typ publikacji:
Letter
MeSH Terms:
Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*drug therapy
Obesity/*complications
Overweight/*complications
Anastrozole ; Body Mass Index ; Breast Neoplasms/complications ; Female ; Humans ; Middle Aged ; Nitriles/therapeutic use ; Postmenopause ; Triazoles/therapeutic use
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Acceptability and adherence in a chemoprevention trial among women at increased risk for breast cancer attending the Modena Familial Breast and Ovarian Cancer Center (Italy).
Autorzy:
Razzaboni E; Department of Oncology and Haematology, Hereditary Breast and Ovarian Cancer Center, University of Modena and Reggio Emilia, Italy. />Toss A
Cortesi L
Marchi I
Sebastiani F
De Matteis E
Federico M
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Źródło:
The breast journal [Breast J] 2013 Jan-Feb; Vol. 19 (1), pp. 10-21. Date of Electronic Publication: 2012 Dec 17.
Typ publikacji:
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Medication Adherence*
Treatment Refusal*
Anticarcinogenic Agents/*therapeutic use
Breast Neoplasms/*prevention & control
Nitriles/*therapeutic use
Triazoles/*therapeutic use
Adult ; Aged ; Analysis of Variance ; Anastrozole ; Anticarcinogenic Agents/adverse effects ; Arthralgia/chemically induced ; Chi-Square Distribution ; Decision Making ; Double-Blind Method ; Eye Diseases/chemically induced ; Female ; Follow-Up Studies ; Hot Flashes/chemically induced ; Humans ; Italy ; Middle Aged ; Nitriles/adverse effects ; Patient Dropouts ; Triazoles/adverse effects ; Vaginal Diseases/chemically induced
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Pathologic changes in breast cancer after anti-estrogen therapy.
Autorzy:
Samarnthai N; Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Elledge R
Prihoda TJ
Huang J
Massarweh S
Yeh IT
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Źródło:
The breast journal [Breast J] 2012 Jul-Aug; Vol. 18 (4), pp. 362-6. Date of Electronic Publication: 2012 May 23.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms:
Breast Neoplasms/*drug therapy
Breast Neoplasms/*pathology
Estrogen Antagonists/*therapeutic use
Aged ; Aged, 80 and over ; Anastrozole ; Biopsy, Large-Core Needle ; Breast Neoplasms/surgery ; Cell Differentiation/drug effects ; Cytoplasm/drug effects ; Estradiol/analogs & derivatives ; Estradiol/therapeutic use ; Female ; Fulvestrant ; Humans ; Middle Aged ; Nitriles/therapeutic use ; Postmenopause ; Receptors, Estrogen/metabolism ; Treatment Outcome ; Triazoles/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Invasive lobular carcinoma of the nipple.
Autorzy:
Erben Y; Department of Surgery, Mayo Clinic, 200 First Street SW., Rochester, MN 55905, USA. />Ghosh K
Nassar A
Gimenez E
Jakub JW
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Źródło:
The breast journal [Breast J] 2012 May-Jun; Vol. 18 (3), pp. 280-1. Date of Electronic Publication: 2012 Apr 05.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Breast Neoplasms/*pathology
Carcinoma, Lobular/*pathology
Nipples/*pathology
Aged ; Anastrozole ; Biopsy ; Breast Neoplasms/surgery ; Breast Neoplasms/therapy ; Carcinoma, Lobular/surgery ; Carcinoma, Lobular/therapy ; Chemoradiotherapy, Adjuvant ; Female ; Humans ; Mastectomy, Segmental ; Nitriles/therapeutic use ; Triazoles/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Evaluation of the psychometric properties of the BCPT Symptom Checklist with a sample of breast cancer patients before and after adjuvant therapy.
Autorzy:
Terhorst L; Center for Research and Evaluation, University of Pittsburgh School of Nursing, Pittsburgh, PA 15261, USA. />Blair-Belansky H
Moore PJ
Bender C
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Źródło:
Psycho-oncology [Psychooncology] 2011 Sep; Vol. 20 (9), pp. 961-8. Date of Electronic Publication: 2010 Jul 28.
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
Breast Neoplasms/*physiopathology
Breast Neoplasms/*psychology
Checklist/*statistics & numerical data
Chemotherapy, Adjuvant/*psychology
Aged ; Anastrozole ; Antineoplastic Agents, Hormonal/therapeutic use ; Breast Neoplasms/drug therapy ; Cognition ; Dyspareunia ; Female ; Hot Flashes ; Humans ; Middle Aged ; Nausea ; Nitriles/therapeutic use ; Pain ; Psychometrics/instrumentation ; Reproducibility of Results ; Self Report ; Triazoles/therapeutic use ; Urinary Incontinence ; Weight Loss
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A case of brain metastases from breast cancer that responded to anastrozole monotherapy.
Autorzy:
Ito K
Ito T
Okada T
Watanabe T
Gomi K
Kanai T
Mochizuki Y
Amano J
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Źródło:
The breast journal [Breast J] 2009 Jul-Aug; Vol. 15 (4), pp. 435-7. Date of Electronic Publication: 2009 May 12.
Typ publikacji:
Case Reports; Letter
MeSH Terms:
Antineoplastic Agents, Hormonal/*therapeutic use
Aromatase Inhibitors/*therapeutic use
Brain Neoplasms/*diagnosis
Brain Neoplasms/*drug therapy
Breast Neoplasms/*complications
Neoplasm Metastasis/*diagnosis
Nitriles/*therapeutic use
Triazoles/*therapeutic use
Aged ; Anastrozole ; Female ; Humans ; Treatment Outcome
Raport
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Enhancing the adjuvant treatment of hormone receptor positive breast cancer.
Autorzy:
Barry M; Breastcheck, Mater Misericordiae University Hospital, University College Dublin, Dublin, Ireland.
Kell MR
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Źródło:
The breast journal [Breast J] 2009 Mar-Apr; Vol. 15 (2), pp. 194-8.
Typ publikacji:
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:
Breast Neoplasms/*drug therapy
Receptors, Estrogen/*analysis
Receptors, Progesterone/*analysis
Aged ; Anastrozole ; Antineoplastic Agents, Hormonal/adverse effects ; Antineoplastic Agents, Hormonal/therapeutic use ; Breast Neoplasms/mortality ; Breast Neoplasms/pathology ; Disease-Free Survival ; Female ; Humans ; Middle Aged ; Nitriles/adverse effects ; Nitriles/therapeutic use ; Postmenopause ; Randomized Controlled Trials as Topic ; Registries ; Survival Analysis ; Survivors ; Triazoles/adverse effects ; Triazoles/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Breast cancer in men: should aromatase inhibitors become first-line hormonal treatment?
Autorzy:
Nordman IC; Department of Medical Oncology, St Vincent's Hospital, Darlinghurst, Sydney, NSW, Australia.
Dalley DN
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Źródło:
The breast journal [Breast J] 2008 Nov-Dec; Vol. 14 (6), pp. 562-9. Date of Electronic Publication: 2008 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
Aromatase Inhibitors/*therapeutic use
Breast Neoplasms, Male/*drug therapy
Adrenalectomy ; Anastrozole ; Aromatase/metabolism ; Breast/enzymology ; Breast Neoplasms/drug therapy ; Breast Neoplasms, Male/surgery ; Estrogens/physiology ; Female ; Humans ; Letrozole ; Male ; Nitriles/therapeutic use ; Orchiectomy ; Postmenopause ; Reference Values ; Sex Characteristics ; Testis/physiology ; Triazoles/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Aromatase inhibitors in the adjuvant treatment of postmenopausal women with early breast cancer: Putting safety issues into perspective.
Autorzy:
Conte P; Department of Oncology and Hematology, The University of Modena and Reggio Emilia, Modena, Italy. conte. />Frassoldati A
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Źródło:
The breast journal [Breast J] 2007 Jan-Feb; Vol. 13 (1), pp. 28-35.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*drug therapy
Neoplasms, Hormone-Dependent/*drug therapy
Anastrozole ; Androstadienes/adverse effects ; Androstadienes/therapeutic use ; Aromatase Inhibitors/adverse effects ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Chemotherapy, Adjuvant ; Female ; Humans ; Letrozole ; Middle Aged ; Neoplasms, Hormone-Dependent/pathology ; Neoplasms, Hormone-Dependent/surgery ; Nitriles/adverse effects ; Nitriles/therapeutic use ; Postmenopause ; Randomized Controlled Trials as Topic ; Safety ; Triazoles/adverse effects ; Triazoles/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 78

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