Temat: "ANASTROZOLE" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Virtual Screening for Identification of Dual Inhibitors against CDK4/6 and Aromatase Enzyme.
Autorzy:: Adon T; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru 570015, Karnataka, India.
Shanmugarajan D; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru 570015, Karnataka, India.
Ather H; Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia.
Ansari SMA; Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia.
Hani U; Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia.
Madhunapantula SV; Department of Biochemistry, JSS Medical College, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India.; Special Interest Group in Cancer Biology and Cancer Stem Cells, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India.
Honnavalli YK; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru 570015, Karnataka, India.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Mar 08; Vol. 28 (6). Date of Electronic Publication: 2023 Mar 08.
Typ publikacji:: Journal Article
MeSH Terms:: Aromatase Inhibitors*/pharmacology
Aromatase Inhibitors*/chemistry
Breast Neoplasms*/drug therapy
Breast Neoplasms*/pathology
Humans ; Female ; Aromatase ; Molecular Docking Simulation ; Anastrozole/therapeutic use ; Molecular Dynamics Simulation ; Enzyme Inhibitors/therapeutic use ; Cyclin-Dependent Kinase 4

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Skocz do pozycji: 2.

Tytuł:: The effect of aromatase inhibitors against possible testis toxicity in pembrolizumab treated rats.
Autorzy:: Türkmen NB; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Inonu University, Malatya, Turkey.
Çiftçi O; Faculty of Medicine, Department of Medicinal Pharmacology, Pamukkale University, Denizli, Turkey.
Taşlıdere A; Faculty of Medicine, Histology and Embryology Department, Inonu University, Malatya, Turkey.
Aydın M; Faculty of Veterinary Medicine, Department of Obstetrics and Gynecology, Firat University, Elazig, Turkey.
Eke BC; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara University, Ankara, Turkey.; Pokaż więcej
Źródło:: Andrologia [Andrologia] 2022 Nov; Vol. 54 (10), pp. e14557. Date of Electronic Publication: 2022 Aug 14.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants*/pharmacology
Aromatase Inhibitors*/pharmacology
Testis*
Anastrozole/pharmacology ; Animals ; Antibodies, Monoclonal, Humanized/toxicity ; Aromatase ; Catalase/pharmacology ; Glutathione ; Glutathione Peroxidase ; Male ; Polyphenols/pharmacology ; Programmed Cell Death 1 Receptor/metabolism ; Rats ; Rats, Sprague-Dawley ; Resveratrol/pharmacology ; Semen ; Sperm Motility ; Superoxide Dismutase/metabolism ; Testosterone ; Thiobarbituric Acid Reactive Substances

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Skocz do pozycji: 3.

Tytuł:: 27-Hydroxycholesterol contributes to cognitive deficits in APP/PS1 transgenic mice through microbiota dysbiosis and intestinal barrier dysfunction.
Autorzy:: Wang Y; School of Public Health, Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, No.10 Xitoutiao, You An Men Wai, Beijing, 100069, China.
An Y; School of Public Health, Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, No.10 Xitoutiao, You An Men Wai, Beijing, 100069, China.
Ma W; School of Public Health, Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, No.10 Xitoutiao, You An Men Wai, Beijing, 100069, China.
Yu H; School of Public Health, Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, No.10 Xitoutiao, You An Men Wai, Beijing, 100069, China.
Lu Y; School of Public Health, Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, No.10 Xitoutiao, You An Men Wai, Beijing, 100069, China.; School of Nursing, Peking University, Beijing, China.
Zhang X; School of Public Health, Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, No.10 Xitoutiao, You An Men Wai, Beijing, 100069, China.
Wang Y; School of Public Health, Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, No.10 Xitoutiao, You An Men Wai, Beijing, 100069, China.
Liu W; School of Public Health, Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, No.10 Xitoutiao, You An Men Wai, Beijing, 100069, China.
Wang T; School of Public Health, Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, No.10 Xitoutiao, You An Men Wai, Beijing, 100069, China.
Xiao R; School of Public Health, Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, No.10 Xitoutiao, You An Men Wai, Beijing, 100069, China. .; Pokaż więcej
Źródło:: Journal of neuroinflammation [J Neuroinflammation] 2020 Jun 27; Vol. 17 (1), pp. 199. Date of Electronic Publication: 2020 Jun 27.
Typ publikacji:: Journal Article
MeSH Terms:: Anastrozole/*pharmacology
Aromatase Inhibitors/*pharmacology
Cognitive Dysfunction/*chemically induced
Dysbiosis/*chemically induced
Gastrointestinal Microbiome/*drug effects
Hydroxycholesterols/*toxicity
Intestines/*drug effects
Animals ; Avoidance Learning/drug effects ; Cognitive Dysfunction/metabolism ; Dysbiosis/metabolism ; Gastrointestinal Microbiome/physiology ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/metabolism ; Male ; Maze Learning/drug effects ; Mice ; Mice, Transgenic ; Tight Junction Proteins/metabolism ; Tight Junctions/drug effects

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Skocz do pozycji: 4.

Tytuł:: [A prospective study of bone loss in early stage postmenopausal breast cancer treated with aromatase inhibitors].
Autorzy:: Sun J; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Wang Q; Department of Ultrasound, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Wang L; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Gui L; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Li Q; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Luo Y; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Zhang S; Department of Cancer Epidemiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Zhang P; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.; Pokaż więcej
Źródło:: Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2020 May 23; Vol. 42 (5), pp. 403-407.
Typ publikacji:: Journal Article
MeSH Terms:: Postmenopause*
Aromatase Inhibitors/*therapeutic use
Bone Density/*drug effects
Breast Neoplasms/*drug therapy
Anastrozole/therapeutic use ; Androstadienes/therapeutic use ; Humans ; Letrozole/therapeutic use ; Prospective Studies

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Skocz do pozycji: 5.

Tytuł:: Leptin Signaling Contributes to Aromatase Inhibitor Resistant Breast Cancer Cell Growth and Activation of Macrophages.
Autorzy:: Gelsomino L; Department of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Giordano C; Department of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Camera G; Department of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Sisci D; Department of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Marsico S; Department of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Campana A; Department of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Tarallo R; Laboratory of Molecular Medicine and Genomics, Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, 84081 Baronissi (SA), Italy.
Rinaldi A; Laboratory of Molecular Medicine and Genomics, Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, 84081 Baronissi (SA), Italy.
Fuqua S; Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, MS: 600 N1220.01 Alkek Building, Houston, TX 77030, USA.
Leggio A; Department of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Grande F; Department of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Bonofiglio D; Department of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Andò S; Department of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Barone I; Department of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.
Catalano S; Department of Pharmacy, Health and Nutritional Sciences, Via P Bucci, University of Calabria, 87036 Arcavacata di Rende (CS), Italy.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2020 Apr 03; Vol. 10 (4). Date of Electronic Publication: 2020 Apr 03.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Drug Resistance, Neoplasm*
Aromatase/*metabolism
Aromatase Inhibitors/*pharmacology
Breast Neoplasms/*pathology
Leptin/*metabolism
Macrophage Activation/*drug effects
Signal Transduction/*drug effects
Anastrozole/pharmacology ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; MCF-7 Cells ; Macrophages/cytology ; Macrophages/drug effects ; Macrophages/immunology ; Receptors, CXCR4/metabolism

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Skocz do pozycji: 6.

Tytuł:: Comparison of Changes in the Lipid Profiles of Eastern Chinese Postmenopausal Women With Early-Stage Breast Cancer Treated With Different Aromatase Inhibitors: A Retrospective Study.
Autorzy:: Tian W; Department of Surgical Oncology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Wu M; Department of Surgical Oncology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Deng Y; Department of Surgical Oncology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Pokaż więcej
Źródło:: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2018 Nov; Vol. 7 (8), pp. 837-843. Date of Electronic Publication: 2017 Dec 29.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Aromatase Inhibitors/*pharmacology
Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*blood
Breast Neoplasms/*drug therapy
Lipid Metabolism/*drug effects
Lipids/*blood
Postmenopause/*blood
Aged ; Anastrozole/pharmacology ; Anastrozole/therapeutic use ; Androstadienes/pharmacology ; Androstadienes/therapeutic use ; Asian People ; China ; Female ; Humans ; Letrozole/pharmacology ; Letrozole/therapeutic use ; Middle Aged ; Retrospective Studies

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Skocz do pozycji: 7.

Tytuł:: Clinical outcomes comparison of 10 years versus 5 years of adjuvant endocrine therapy in patients with early breast cancer.
Autorzy:: Li L; Department of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Chang B; Department of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.; Department of Biochemistry and Molecular Biology, Basic Medical College, Shanxi Medical University, Taiyuan, 030001, China.
Jiang X; Department of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Fan X; Gastroenterology Department, JinCheng People's Hospital, Shanxi, 048000, China.
Li Y; Biochemistry and Molecular Biology, Basic Medicine College, Shanxi Medical University, Taiyuan, 050001, China.
Li T; Department of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Wu S; Statistical Center, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Zhang J; Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, 77030, USA.
Kariminia S; Molecular and Cellular Oncology, MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, 77030, USA.
Li Q; Department of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2018 Oct 12; Vol. 18 (1), pp. 977. Date of Electronic Publication: 2018 Oct 12.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*drug therapy
Tamoxifen/*therapeutic use
Age of Onset ; Anastrozole/therapeutic use ; Androstadienes/therapeutic use ; Chemotherapy, Adjuvant ; Female ; Humans ; Letrozole/therapeutic use ; Postmenopause ; Prospective Studies ; Treatment Outcome

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Skocz do pozycji: 8.

Tytuł:: Extended Adjuvant Endocrine Therapy in Breast Cancer: Evidence and Update - A Review.
Autorzy:: Jinih M; Department of Academic Surgery, Cork University Hospital (CUH), National University of Ireland (Cork), Wilton, Cork, Ireland.
Relihan N; Department of Academic Surgery, Cork University Hospital (CUH), National University of Ireland (Cork), Wilton, Cork, Ireland.
Corrigan MA; Department of Academic Surgery, Cork University Hospital (CUH), National University of Ireland (Cork), Wilton, Cork, Ireland.
O'Reilly S; Department of Medical Oncology, Cork University Hospital (CUH), National University of Ireland (Cork), Wilton, Cork, Ireland.
Redmond HP; Department of Academic Surgery, Cork University Hospital (CUH), National University of Ireland (Cork), Wilton, Cork, Ireland.; Pokaż więcej
Źródło:: The breast journal [Breast J] 2017 Nov; Vol. 23 (6), pp. 694-705. Date of Electronic Publication: 2017 Mar 02.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Antineoplastic Agents, Hormonal/*administration & dosage
Aromatase Inhibitors/*administration & dosage
Breast Neoplasms/*drug therapy
Neoplasm Recurrence, Local/*drug therapy
Nitriles/*administration & dosage
Tamoxifen/*administration & dosage
Triazoles/*administration & dosage
Anastrozole ; Chemotherapy, Adjuvant ; Clinical Trials as Topic ; Drug Administration Schedule ; Female ; Humans

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Skocz do pozycji: 9.

Tytuł:: Mechanism of Bushen Jianpi decoction in preventing and treating osteoporosis caused by aromatase inhibitors in breast cancer treatment.
Autorzy:: Huang XH; Department of Traditional Chinese Medicine, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong, China.
Liang RH; Guangzhou University of Chinese Medicine, Guangzhou 510403, Guangdong, China.
Su L; Guangzhou University of Chinese Medicine, Guangzhou 510403, Guangdong, China.
Guo W; Guangzhou University of Chinese Medicine, Guangzhou 510403, Guangdong, China.
Wang CJ; Department of Traditional Chinese Medicine, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong, China.; Pokaż więcej
Źródło:: Cancer biomarkers : section A of Disease markers [Cancer Biomark] 2017; Vol. 18 (2), pp. 183-190.
Typ publikacji:: Journal Article
MeSH Terms:: Aromatase Inhibitors/*adverse effects
Bone Density Conservation Agents/*pharmacology
Breast Neoplasms/*drug therapy
Drugs, Chinese Herbal/*pharmacology
Osteoporosis/*prevention & control
Alendronate/pharmacology ; Alkaline Phosphatase/blood ; Anastrozole ; Animals ; Bone Density/drug effects ; Breast Neoplasms/pathology ; Disease Models, Animal ; Female ; Mice, Inbred BALB C ; Nitriles/adverse effects ; Osteoporosis/chemically induced ; Osteoporosis/drug therapy ; Ovariectomy ; Triazoles/adverse effects

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Skocz do pozycji: 10.

Tytuł:: Anastrozole: carpal tunnel syndrome. Possibly a hormonal mechanism.
Źródło:: Prescrire international [Prescrire Int] 2016 Oct; Vol. 25 (175), pp. 242.
Typ publikacji:: Journal Article
MeSH Terms:: Anastrozole/*adverse effects
Aromatase Inhibitors/*adverse effects
Carpal Tunnel Syndrome/*chemically induced
Carpal Tunnel Syndrome/diagnosis ; Female ; Humans ; Risk Assessment ; Risk Factors

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Skocz do pozycji: 11.

Tytuł:: Effects of aromatase inhibition vs. testosterone in older men with low testosterone: randomized-controlled trial.
Autorzy:: Dias JP; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, USA.
Melvin D; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, USA.
Simonsick EM; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.
Carlson O; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, USA.
Shardell MD; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.
Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.
Chia CW; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.
Basaria S; Section on Men's Health, Aging and Metabolism, Brigham and Women's Hospital Harvard Medical School, Boston, MA, USA.
Egan JM; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, USA.; Pokaż więcej
Źródło:: Andrology [Andrology] 2016 Jan; Vol. 4 (1), pp. 33-40. Date of Electronic Publication: 2015 Nov 20.
Typ publikacji:: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Intramural
MeSH Terms:: Aromatase Inhibitors/*therapeutic use
Body Composition/*drug effects
Bone Density/*drug effects
Nitriles/*therapeutic use
Testosterone/*blood
Testosterone/*therapeutic use
Triazoles/*therapeutic use
Aged ; Aged, 80 and over ; Aging ; Anastrozole ; Aromatase/drug effects ; Bone and Bones/physiology ; Double-Blind Method ; Estradiol/blood ; Humans ; Male ; Placebos

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Skocz do pozycji: 12.

Tytuł:: Case report: anti-hormonal therapy in the treatment of ductal carcinoma of the parotid gland.
Autorzy:: Campos-Gómez S; Departamento de Oncología Médica, Centro Oncológico Estatal, ISSEMYM, Toluca, México. .
Flores-Arredondo JH
Dorantes-Heredia R
Chapa-Ibargüengoitia M
de la Peña-Lopez R; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2014 Sep 23; Vol. 14, pp. 701. Date of Electronic Publication: 2014 Sep 23.
Typ publikacji:: Case Reports; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Antineoplastic Agents, Hormonal/*administration & dosage
Aromatase Inhibitors/*administration & dosage
Carcinoma, Ductal/*drug therapy
Parotid Neoplasms/*drug therapy
Aged ; Anastrozole ; Antineoplastic Agents, Hormonal/therapeutic use ; Aromatase Inhibitors/therapeutic use ; Carcinoma, Ductal/pathology ; Carcinoma, Ductal/surgery ; Disease-Free Survival ; Female ; Humans ; Neoplasm Metastasis ; Nitriles/administration & dosage ; Nitriles/therapeutic use ; Parotid Neoplasms/pathology ; Parotid Neoplasms/surgery ; Tamoxifen/administration & dosage ; Tamoxifen/therapeutic use ; Treatment Outcome ; Triazoles/administration & dosage ; Triazoles/therapeutic use

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Skocz do pozycji: 13.

Tytuł:: Prevalence of menopausal symptoms and their influence on adherence in women with breast cancer.
Autorzy:: Kyvernitakis I; Department of Gynecological Endocrinology, Reproductive Medicine and Osteoporosis , Phillips University of Marburg, Marburg , Germany.
Ziller V
Hars O
Bauer M
Kalder M
Hadji P; Pokaż więcej
Źródło:: Climacteric : the journal of the International Menopause Society [Climacteric] 2014 Jun; Vol. 17 (3), pp. 252-9. Date of Electronic Publication: 2013 Aug 25.
Typ publikacji:: Journal Article; Randomized Controlled Trial
MeSH Terms:: Medication Adherence*
Antineoplastic Agents, Hormonal/*adverse effects
Aromatase Inhibitors/*adverse effects
Breast Neoplasms/*drug therapy
Aged ; Anastrozole ; Anxiety/chemically induced ; Chemotherapy, Adjuvant ; Female ; Hot Flashes/chemically induced ; Humans ; Letrozole ; Middle Aged ; Musculoskeletal Pain/chemically induced ; Nitriles/adverse effects ; Sleep Wake Disorders/chemically induced ; Time Factors ; Triazoles/adverse effects ; Urinary Bladder Diseases/chemically induced ; Vaginal Diseases/chemically induced

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Skocz do pozycji: 14.

Tytuł:: A pilot study comparing the effect of flaxseed, aromatase inhibitor, and the combination on breast tumor biomarkers.
Autorzy:: McCann SE; a Department of Cancer Prevention and Control , Roswell Park Cancer Institute , Buffalo , New York , USA.
Edge SB
Hicks DG
Thompson LU
Morrison CD
Fetterly G
Andrews C
Clark K
Wilton J
Kulkarni S; Pokaż więcej
Źródło:: Nutrition and cancer [Nutr Cancer] 2014; Vol. 66 (4), pp. 566-75. Date of Electronic Publication: 2014 Mar 26.
Typ publikacji:: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms:: Aromatase Inhibitors/*pharmacology
Biomarkers, Tumor/*blood
Breast Neoplasms/*drug therapy
Flax/*chemistry
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anastrozole ; Body Mass Index ; Breast Neoplasms/blood ; Estrogen Receptor beta/genetics ; Estrogen Receptor beta/metabolism ; Female ; Gonadal Steroid Hormones/blood ; Humans ; Lignans/urine ; Linear Models ; Middle Aged ; Nitriles/pharmacology ; Pilot Projects ; Treatment Outcome ; Triazoles/pharmacology ; Young Adult

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Skocz do pozycji: 15.

Tytuł:: Aromatase inhibitors associated with knee subchondral bone expansion without cartilage loss.
Autorzy:: Davis SR; School of Public Health and Preventive Medicine, Monash University , Melbourne , Victoria.
Bell RJ
Wang Y
Hanna F
Davies-Tuck M
Bell R
Chirgwin J
Cicuttini F; Pokaż więcej
Źródło:: Climacteric : the journal of the International Menopause Society [Climacteric] 2013 Dec; Vol. 16 (6), pp. 632-8. Date of Electronic Publication: 2012 Dec 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Aromatase Inhibitors/*pharmacology
Breast Neoplasms/*drug therapy
Menisci, Tibial/*drug effects
Tibia/*drug effects
Anastrozole ; Case-Control Studies ; Female ; Humans ; Letrozole ; Magnetic Resonance Imaging ; Menisci, Tibial/anatomy & histology ; Middle Aged ; Nitriles/pharmacology ; Postmenopause ; Prospective Studies ; Tibia/pathology ; Triazoles/pharmacology

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Skocz do pozycji: 16.

Tytuł:: Expression of estrogen-related gene markers in breast cancer tissue predicts aromatase inhibitor responsiveness.
Autorzy:: Moy I; Northwestern University, Department of Obstetrics and Gynecology, Chicago, Illinois, United States of America.
Lin Z
Rademaker AW
Reierstad S
Khan SA
Bulun SE; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013 Nov 06; Vol. 8 (11), pp. e77543. Date of Electronic Publication: 2013 Nov 06 (Print Publication: 2013).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents, Hormonal/*pharmacology
Aromatase Inhibitors/*pharmacology
Biomarkers, Tumor/*genetics
Breast Neoplasms/*genetics
Nitriles/*pharmacology
Triazoles/*pharmacology
3-Hydroxysteroid Dehydrogenases/genetics ; 3-Hydroxysteroid Dehydrogenases/metabolism ; Aldo-Keto Reductase Family 1 Member C3 ; Anastrozole ; Antineoplastic Agents, Hormonal/therapeutic use ; Aromatase/genetics ; Aromatase/metabolism ; Aromatase Inhibitors/therapeutic use ; BRCA1 Protein/genetics ; BRCA1 Protein/metabolism ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Chemotherapy, Adjuvant ; Drug Resistance, Neoplasm ; Estrogen Receptor alpha/genetics ; Estrogen Receptor alpha/metabolism ; Estrogens/physiology ; Female ; Gene Expression Regulation, Neoplastic ; Genetic Markers ; Humans ; Hydroxyprostaglandin Dehydrogenases/genetics ; Hydroxyprostaglandin Dehydrogenases/metabolism ; Letrozole ; Middle Aged ; Nitriles/therapeutic use ; ROC Curve ; Receptors, Progesterone/genetics ; Receptors, Progesterone/metabolism ; Tamoxifen/pharmacology ; Tamoxifen/therapeutic use ; Treatment Outcome ; Triazoles/therapeutic use

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Skocz do pozycji: 17.

Tytuł:: Impact of body mass index on estradiol depletion by aromatase inhibitors in postmenopausal women with early breast cancer.
Autorzy:: Pfeiler G; Division of Gynecology and Gynecological Oncology, Department of OB/GYN, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Königsberg R
Hadji P
Fitzal F
Maroske M
Dressel-Ban G
Zellinger J
Exner R
Seifert M
Singer C
Gnant M
Dubsky P; Pokaż więcej
Źródło:: British journal of cancer [Br J Cancer] 2013 Sep 17; Vol. 109 (6), pp. 1522-7. Date of Electronic Publication: 2013 Sep 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Body Mass Index*
Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*blood
Breast Neoplasms/*drug therapy
Estradiol/*blood
Aged ; Aged, 80 and over ; Anastrozole ; Estradiol/deficiency ; Female ; Humans ; Letrozole ; Middle Aged ; Nitriles/therapeutic use ; Obesity/blood ; Postmenopause/blood ; Prospective Studies ; Receptors, Estrogen/metabolism ; Survival Analysis ; Triazoles/therapeutic use

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Skocz do pozycji: 18.

Tytuł:: A polymorphism at the 3'-UTR region of the aromatase gene is associated with the efficacy of the aromatase inhibitor, anastrozole, in metastatic breast carcinoma.
Autorzy:: Liu L; Department of Internal Medicine, The Affiliated Tumor Hospital, Harbin Medical University, Haping Road 150 of Nangang District, Harbin 150081, Heilongjiang, China. .
Bai YX
Zhou JH
Sun XW
Sui H
Zhang WJ
Yuan HH
Xie R
Wei XL
Zhang TT
Huang P
Li YJ
Wang JX
Zhao S
Zhang QY; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2013 Sep 13; Vol. 14 (9), pp. 18973-88. Date of Electronic Publication: 2013 Sep 13.
Typ publikacji:: Journal Article
MeSH Terms:: Aromatase/*genetics
Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*genetics
Nitriles/*therapeutic use
Triazoles/*therapeutic use
17-Hydroxysteroid Dehydrogenases/genetics ; 3' Untranslated Regions ; Adult ; Aged ; Aged, 80 and over ; Alleles ; Alpha-Ketoglutarate-Dependent Dioxygenase FTO ; Anastrozole ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Female ; Gene Frequency ; Genotype ; Humans ; Middle Aged ; Polymorphism, Single Nucleotide ; Proteins/genetics ; Retrospective Studies ; Survival Analysis

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Tytuł:: Adjuvant aromatase inhibitor options in overweight and obese postmenopausal women with breast cancer.
Autorzy:: Chlebowski RT; Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California.; Pokaż więcej
Źródło:: The breast journal [Breast J] 2013 Sep-Oct; Vol. 19 (5), pp. 552-4. Date of Electronic Publication: 2013 Aug 14.
Typ publikacji:: Letter
MeSH Terms:: Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*drug therapy
Obesity/*complications
Overweight/*complications
Anastrozole ; Body Mass Index ; Breast Neoplasms/complications ; Female ; Humans ; Middle Aged ; Nitriles/therapeutic use ; Postmenopause ; Triazoles/therapeutic use