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Tytuł:
The Role of the CD28 Family Receptors in T-Cell Immunomodulation.
Autorzy:
Ciesielska-Figlon K; Department of Physiopathology, Medical University of Gdansk, 80-211 Gdansk, Poland.
Lisowska KA; Department of Physiopathology, Medical University of Gdansk, 80-211 Gdansk, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 20; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
CD28 Antigens*
T-Lymphocytes*
CTLA-4 Antigen ; Programmed Cell Death 1 Receptor ; Antigens, CD ; Immunity ; Immunomodulation ; Antigens, Differentiation, T-Lymphocyte ; Lymphocyte Activation
Czasopismo naukowe
Tytuł:
CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models.
Autorzy:
Timpanaro A; Department of Pediatric Hematology and Oncology, Inselspital, Bern University Hospital, 3010, Bern, Switzerland.; Translational Cancer Research, Department for BioMedical Research (DBMR), University of Bern, 3008, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012, Bern, Switzerland.
Piccand C; Department of Pediatric Hematology and Oncology, Inselspital, Bern University Hospital, 3010, Bern, Switzerland.; Translational Cancer Research, Department for BioMedical Research (DBMR), University of Bern, 3008, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012, Bern, Switzerland.
Dzhumashev D; Department of Pediatric Hematology and Oncology, Inselspital, Bern University Hospital, 3010, Bern, Switzerland.; Translational Cancer Research, Department for BioMedical Research (DBMR), University of Bern, 3008, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012, Bern, Switzerland.
Anton-Joseph S; Department of Pediatric Hematology and Oncology, Inselspital, Bern University Hospital, 3010, Bern, Switzerland.; Translational Cancer Research, Department for BioMedical Research (DBMR), University of Bern, 3008, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012, Bern, Switzerland.
Robbi A; Department of Pediatric Hematology and Oncology, Inselspital, Bern University Hospital, 3010, Bern, Switzerland.; Translational Cancer Research, Department for BioMedical Research (DBMR), University of Bern, 3008, Bern, Switzerland.
Moser J; Department of Pediatric Hematology and Oncology, Inselspital, Bern University Hospital, 3010, Bern, Switzerland.; Translational Cancer Research, Department for BioMedical Research (DBMR), University of Bern, 3008, Bern, Switzerland.
Rössler J; Department of Pediatric Hematology and Oncology, Inselspital, Bern University Hospital, 3010, Bern, Switzerland.; Translational Cancer Research, Department for BioMedical Research (DBMR), University of Bern, 3008, Bern, Switzerland.
Bernasconi M; Department of Pediatric Hematology and Oncology, Inselspital, Bern University Hospital, 3010, Bern, Switzerland. .; Translational Cancer Research, Department for BioMedical Research (DBMR), University of Bern, 3008, Bern, Switzerland. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Nov 04; Vol. 42 (1), pp. 293. Date of Electronic Publication: 2023 Nov 04.
Typ publikacji:
Journal Article
MeSH Terms:
B7 Antigens*/metabolism
Receptor, Fibroblast Growth Factor, Type 4*/metabolism
Rhabdomyosarcoma*/therapy
Rhabdomyosarcoma*/pathology
T-Lymphocytes*
Animals ; Mice ; CD28 Antigens/metabolism ; Cell Line, Tumor ; Neoplasm Recurrence, Local/metabolism
Czasopismo naukowe
Tytuł:
COSMIC-based mutation database enhances identification efficiency of HLA-I immunopeptidome.
Autorzy:
Wang F; Medical School of Chinese People's Liberation Army (PLA), Faculty of Hepato-Pancreato-Biliary Surgery, Chinese PLA General Hospital, Institute of Hepatobiliary Surgery of Chinese PLA, Key Laboratory of Digital Hepatobiliary Surgery PLA, 28 Fuxing Road, Haidian District, Beijing, 100853, China.
Zhang Z; State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics and Research and Development of New Drug of Chinese Academy of Medical Sciences, Beijing Proteome Research Center, Institute of Lifeomics, 38 Life Science Park Road, Changping District, Beijing, 102206, China.
Mao M; State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics and Research and Development of New Drug of Chinese Academy of Medical Sciences, Beijing Proteome Research Center, Institute of Lifeomics, 38 Life Science Park Road, Changping District, Beijing, 102206, China.; School of Basic Medical Sciences, Anhui Medical University, Hefei, China.
Yang Y; State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics and Research and Development of New Drug of Chinese Academy of Medical Sciences, Beijing Proteome Research Center, Institute of Lifeomics, 38 Life Science Park Road, Changping District, Beijing, 102206, China.; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Xu P; State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics and Research and Development of New Drug of Chinese Academy of Medical Sciences, Beijing Proteome Research Center, Institute of Lifeomics, 38 Life Science Park Road, Changping District, Beijing, 102206, China. .; School of Basic Medical Sciences, Anhui Medical University, Hefei, China. .; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. .; School of Medicine, Guizhou University, Guiyang, China. .
Lu S; Medical School of Chinese People's Liberation Army (PLA), Faculty of Hepato-Pancreato-Biliary Surgery, Chinese PLA General Hospital, Institute of Hepatobiliary Surgery of Chinese PLA, Key Laboratory of Digital Hepatobiliary Surgery PLA, 28 Fuxing Road, Haidian District, Beijing, 100853, China. lusc_.
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Feb 10; Vol. 22 (1), pp. 144. Date of Electronic Publication: 2024 Feb 10.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Neoplasm*/metabolism
Histocompatibility Antigens Class I*/genetics
Histocompatibility Antigens Class I*/metabolism
T-Lymphocytes*
Databases, Genetic*
Humans ; Mutation/genetics ; Peptides/chemistry
Czasopismo naukowe
Tytuł:
Reassessing human MHC-I genetic diversity in T cell studies.
Autorzy:
Slieker RC; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.; Leiden Center for Computational Oncology, Leiden University Medical Center, Leiden, The Netherlands.
Warmerdam DO; Centre for Future Affordable & Sustainable Therapy Development (FAST), The Hague, The Netherlands.
Vermeer MH; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands.
van Doorn R; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Dermatology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Heemskerk MHM; Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands.
Scheeren FA; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands. .
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Źródło:
Scientific reports [Sci Rep] 2024 Apr 04; Vol. 14 (1), pp. 7966. Date of Electronic Publication: 2024 Apr 04.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*
COVID-19*/genetics
Humans ; Australia ; Histocompatibility Antigens Class I/genetics ; HLA Antigens/genetics ; Genetic Variation ; Histocompatibility Antigens Class II/genetics ; Major Histocompatibility Complex ; Alleles
Czasopismo naukowe
Tytuł:
CAR T cells and T cells phenotype and function are impacted by glucocorticoid exposure with different magnitude.
Autorzy:
Poiret T; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden. .
Vikberg S; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Schoutrop E; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Mattsson J; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.; Gloria and Seymour Epstein Chair in Cell Therapy and Transplantation, Princess Margaret Cancer Centre and University of Toronto; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Magalhaes I; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.; Department of Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden.
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Mar 12; Vol. 22 (1), pp. 273. Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*
Receptors, Chimeric Antigen*/metabolism
Glucocorticoids ; Programmed Cell Death 1 Receptor/metabolism ; Immunotherapy, Adoptive ; Phenotype ; Antigens, CD19/metabolism
Czasopismo naukowe
Tytuł:
Random walk informed heterogeneity detection reveals how the lymph node conduit network influences T cells collective exploration behavior.
Autorzy:
Song S; Aix Marseille Univ, Université de Toulon, CNRS, LIS Turing Centre for Living Systems, Marseille, France.
Senoussi M; Aix Marseille Univ, Université de Toulon, CNRS, LIS Turing Centre for Living Systems, Marseille, France.
Escande P; Aix Marseille Univ, CNRS, Centrale Marseille, I2M, Marseille, France.
Villoutreix P; Aix Marseille Univ, Université de Toulon, CNRS, LIS Turing Centre for Living Systems, Marseille, France.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2023 May 24; Vol. 19 (5), pp. e1011168. Date of Electronic Publication: 2023 May 24 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
T-Lymphocytes*
Antigens*
Lymph Nodes ; Stochastic Processes
Czasopismo naukowe
Tytuł:
Vγ9+Vδ2+ T cell control of Listeria monocytogenes growth in infected epithelial cells requires butyrophilin 3A genes.
Autorzy:
Fischer K; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.; Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna, Vienna, Austria.
Bradlerova M; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.; Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna, Vienna, Austria.
Decker T; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria. .; Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna, Vienna, Austria. .
Supper V; Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria.
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 30; Vol. 13 (1), pp. 18651. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
T-Lymphocytes*
Listeria monocytogenes*/metabolism
Humans ; Receptors, Antigen, T-Cell, gamma-delta/metabolism ; Butyrophilins/genetics ; Butyrophilins/metabolism ; Antigens ; Epithelial Cells/metabolism ; Lymphocyte Activation ; Antigens, CD/metabolism
Czasopismo naukowe
Tytuł:
Butyrophilins: Dynamic Regulators of Protective T Cell Immunity in Cancer.
Autorzy:
Kumari R; Medical Immunology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA.
Hosseini ES; Medical Immunology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA.; Cellular and Molecular Pharmacology, Rutgers School of Graduate Studies, Rutgers, The State University of New Jersey, New Brunswick, NJ 08854, USA.
Warrington KE; Medical Immunology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA.
Milonas T; Medical Immunology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA.
Payne KK; Medical Immunology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA.; Cellular and Molecular Pharmacology, Rutgers School of Graduate Studies, Rutgers, The State University of New Jersey, New Brunswick, NJ 08854, USA.; Department of Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ 08901, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 13; Vol. 24 (10). Date of Electronic Publication: 2023 May 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
T-Lymphocytes*
Neoplasms*/therapy
Humans ; Butyrophilins/genetics ; Butyrophilins/metabolism ; Immunity, Cellular ; Antigens ; Receptors, Antigen, T-Cell, gamma-delta ; Lymphocyte Activation ; Antigens, CD/metabolism
Czasopismo naukowe
Tytuł:
Cell activation-based screening of natively paired human T cell receptor repertoires.
Autorzy:
Fahad AS; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, 66044, USA.
Chung CY; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, 66044, USA.
López Acevedo SN; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, 66044, USA.
Boyle N; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, 66044, USA.
Madan B; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, 66044, USA.
Gutiérrez-González MF; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, 66044, USA.
Matus-Nicodemos R; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Laflin AD; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, 66044, USA.
Ladi RR; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, 66044, USA.
Zhou J; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, 66044, USA.
Wolfe J; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, 66044, USA.
Llewellyn-Lacey S; Division of Infection and Immunity, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, CF14 4XN, UK.
Koup RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Douek DC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Balfour HH Jr; Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN, 55455, USA.; Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, 55455, USA.
Price DA; Division of Infection and Immunity, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, CF14 4XN, UK.; Systems Immunity Research Institute, Cardiff University School of Medicine, University Hospital of Wales, Cardiff, CF14 4XN, UK.
DeKosky BJ; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, 66044, USA. .; Department of Chemical Engineering, The University of Kansas, Lawrence, KS, 66044, USA. .; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA. .; The Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 May 17; Vol. 13 (1), pp. 8011. Date of Electronic Publication: 2023 May 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
T-Lymphocytes*
Receptors, Antigen, T-Cell*
Humans ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Cloning, Molecular ; Antigens ; Peptides/genetics
Czasopismo naukowe
Tytuł:
Siglec-5 is an inhibitory immune checkpoint molecule for human T cells.
Autorzy:
Vuchkovska A; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA.; Van Kampen Cardiopulmonary Research Laboratory, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA.
Glanville DG; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA.
Scurti GM; Department of Surgery, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA.
Nishimura MI; Department of Surgery, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA.
White P; Department of Gynecology and Obstetrics, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA.
Ulijasz AT; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA.
Iwashima M; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA.; Van Kampen Cardiopulmonary Research Laboratory, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA.
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Źródło:
Immunology [Immunology] 2022 Jun; Vol. 166 (2), pp. 238-248. Date of Electronic Publication: 2022 Apr 01.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD*/metabolism
Antigens, Differentiation, Myelomonocytic*/metabolism
Immune Checkpoint Proteins*/metabolism
Lectins*/metabolism
T-Lymphocytes*/metabolism
Humans ; Immunoglobulins ; Ligands ; Sialic Acid Binding Immunoglobulin-like Lectins ; Tyrosine
Czasopismo naukowe
Tytuł:
T cell immune responses deciphered.
Autorzy:
Nourmohammad A; Department of Physics, University of Washington, Seattle, WA, USA.; Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Max Planck Institute for Dynamics and Self-Organization, Göttingen, Germany.
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Źródło:
Science (New York, N.Y.) [Science] 2022 May 20; Vol. 376 (6595), pp. 796-797. Date of Electronic Publication: 2022 May 19.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Adaptive Immunity*
Antigens*/classification
Antigens*/immunology
Machine Learning*
T-Lymphocytes*/immunology
Animals ; Antigen Presentation ; Humans ; Mice
Czasopismo naukowe
Tytuł:
PD-1-CD28 fusion protein strengthens mesothelin-specific TRuC T cells in preclinical solid tumor models.
Autorzy:
Lesch S; Center of Integrated Protein Science Munich (CIPS-M) and Division of Clinical Pharmacology, Department of Medicine IV, Member of the German Center for Lung Research (DZL), University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany.
Nottebrock A; Center of Integrated Protein Science Munich (CIPS-M) and Division of Clinical Pharmacology, Department of Medicine IV, Member of the German Center for Lung Research (DZL), University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany.
Rataj F; Center of Integrated Protein Science Munich (CIPS-M) and Division of Clinical Pharmacology, Department of Medicine IV, Member of the German Center for Lung Research (DZL), University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany.
Heise C; Center of Integrated Protein Science Munich (CIPS-M) and Division of Clinical Pharmacology, Department of Medicine IV, Member of the German Center for Lung Research (DZL), University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany.
Endres S; Center of Integrated Protein Science Munich (CIPS-M) and Division of Clinical Pharmacology, Department of Medicine IV, Member of the German Center for Lung Research (DZL), University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany.; German Center for Translational Cancer Research (DKTK), partner site Munich, Munich, Germany.; Einheit Für Klinische Pharmakologie (EKLiP), Helmholtz Zentrum München, Germany, Research Center for Environmental Health (HMGU), Neuherberg, Germany.
Kobold S; Center of Integrated Protein Science Munich (CIPS-M) and Division of Clinical Pharmacology, Department of Medicine IV, Member of the German Center for Lung Research (DZL), University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany. .; German Center for Translational Cancer Research (DKTK), partner site Munich, Munich, Germany. .; Einheit Für Klinische Pharmakologie (EKLiP), Helmholtz Zentrum München, Germany, Research Center for Environmental Health (HMGU), Neuherberg, Germany. .; Division of Clinical Pharmacology, Klinikum der Universität München, Lindwurmstraße 2a, 80337, Munich, Germany. .
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2023 Feb; Vol. 46 (1), pp. 227-235. Date of Electronic Publication: 2022 Nov 21.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*
Neoplasms*
Humans ; Mice ; Animals ; CD28 Antigens/metabolism ; Programmed Cell Death 1 Receptor/metabolism ; B7-H1 Antigen/metabolism ; Mesothelin ; Receptors, Antigen, T-Cell/metabolism ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Human delta like 1-expressing human mesenchymal stromal cells promote human T cell development and antigen-specific response in humanized NOD/SCID/IL-2R[Formula: see text] (NSG) mice.
Autorzy:
Kwon DH; Department of Immunology and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, 2066 Seobu-ro, Jangan-gu, Suwon, 16419 Gyeonggi-do Korea.
Park JB; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea.
Lee JS; Department of Precision Medicine, Sungkyunkwan University School of Medicine, Suwon-Si, 440-746 Kyonggi-Do Korea.; Single Cell Network Research Center, Sungkyunkwan University School of Medicine, Suwon, 16419 Republic of Korea.
Kim SJ; GenNBio, Inc., Seoul, Republic of Korea.; Department of Medicine, Sungkyunkwan University School of Medicine, Suwon-Si, Kyonggi-Do, 440-746 Korea.
Choi B; GenNBio, Inc., Seoul, Republic of Korea.; Department of Medicine, Sungkyunkwan University School of Medicine, Suwon-Si, Kyonggi-Do, 440-746 Korea.
Lee KY; Department of Immunology and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, 2066 Seobu-ro, Jangan-gu, Suwon, 16419 Gyeonggi-do Korea.; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea.; Single Cell Network Research Center, Sungkyunkwan University School of Medicine, Suwon, 16419 Republic of Korea.
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Źródło:
Scientific reports [Sci Rep] 2021 May 19; Vol. 11 (1), pp. 10603. Date of Electronic Publication: 2021 May 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunity*
Antigens/*immunology
Calcium-Binding Proteins/*metabolism
Membrane Proteins/*metabolism
Mesenchymal Stem Cells/*metabolism
T-Lymphocytes/*cytology
T-Lymphocytes/*immunology
Animals ; Antigens, CD34/metabolism ; Epstein-Barr Virus Infections/immunology ; Fetal Blood/cytology ; Fetus/embryology ; Herpesvirus 4, Human/immunology ; Humans ; Liver/cytology ; Liver/embryology ; Lymphocyte Activation/immunology ; Mice, Inbred NOD ; Mice, SCID ; Mice
Czasopismo naukowe
Tytuł:
COVID-19 Pandemic: Escape of Pathogenic Variants and MHC Evolution.
Autorzy:
Pontarotti P; Evolutionary Biology Team, MEPHI, Aix Marseille Université, IRD, APHM, IHU MI, 19-21 Boulevard Jean Moulin, 13005 Marseille, France.; SNC 5039 CNRS, 13005 Marseille, France.; Xegen, 15 Rue Dominique Piazza, 13420 Gemenos, France.
Paganini J; Xegen, 15 Rue Dominique Piazza, 13420 Gemenos, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Feb 28; Vol. 23 (5). Date of Electronic Publication: 2022 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19/*immunology
HLA Antigens/*immunology
Polymorphism, Genetic/*immunology
SARS-CoV-2/*immunology
T-Lymphocytes/*immunology
COVID-19/epidemiology ; COVID-19/virology ; Evolution, Molecular ; Gene Frequency ; HLA Antigens/genetics ; HLA Antigens/metabolism ; Humans ; Immunity, Innate/genetics ; Immunity, Innate/immunology ; Mutation/genetics ; Mutation/immunology ; Pandemics ; Peptides/immunology ; Peptides/metabolism ; Polymorphism, Genetic/genetics ; SARS-CoV-2/physiology ; T-Lymphocytes/cytology ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł:
Isoginkgetin derivative IP2 enhances the adaptive immune response against tumor antigens.
Autorzy:
Darrigrand R; Université Paris-Saclay, Institut Gustave Roussy, Inserm, Immunologie des tumeurs et Immunothérapie, Villejuif, France.
Pierson A; Université Paris-Saclay, Institut Gustave Roussy, Inserm, Immunologie des tumeurs et Immunothérapie, Villejuif, France.
Rouillon M; Université Paris-Saclay, Institut Gustave Roussy, Inserm, Immunologie des tumeurs et Immunothérapie, Villejuif, France.; SATT Paris Saclay, Orsay, France.
Renko D; Université Paris-Saclay, CNRS, BioCIS, Châtenay-Malabry, France.
Boulpicante M; Université Paris-Saclay, Institut Gustave Roussy, Inserm, Immunologie des tumeurs et Immunothérapie, Villejuif, France.
Bouyssié D; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.
Mouton-Barbosa E; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.
Marcoux J; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.
Garcia C; Institut Jacques Monod, CNRS U7592 Université Paris Diderot, Paris, France.; Institut Pasteur, Unité de Spectrométrie de Masse pour la Biologie (MSBio), Centre de Ressources et Recherches Technologiques (C2RT), USR 2000 CNRS, Paris, France.
Ghosh M; Department of Immunology, Interfaculty Institute for Cell Biology, University of Tübingen, Tübingen, Germany.
Alami M; Université Paris-Saclay, CNRS, BioCIS, Châtenay-Malabry, France.
Apcher S; Université Paris-Saclay, Institut Gustave Roussy, Inserm, Immunologie des tumeurs et Immunothérapie, Villejuif, France. .
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Źródło:
Communications biology [Commun Biol] 2021 Mar 01; Vol. 4 (1), pp. 269. Date of Electronic Publication: 2021 Mar 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adaptive Immunity/*drug effects
Antigens, Neoplasm/*metabolism
Antineoplastic Agents, Phytogenic/*pharmacology
Biflavonoids/*pharmacology
Cancer Vaccines/*pharmacology
Fibrosarcoma/*drug therapy
Lymphocytes, Tumor-Infiltrating/*drug effects
T-Lymphocytes/*drug effects
Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Female ; Fibrosarcoma/immunology ; Fibrosarcoma/metabolism ; Fibrosarcoma/pathology ; Histocompatibility Antigens Class I/immunology ; Histocompatibility Antigens Class I/metabolism ; Imidazoline Receptors/immunology ; Imidazoline Receptors/metabolism ; Lymphocyte Activation/drug effects ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Mice ; Mice, Inbred C57BL ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Tumor Burden/drug effects ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells.
Autorzy:
Jin H; Medicinal Chemistry Core, Oregon Health & Science University, Portland, OR, 97239, USA.
Ladd NA; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, 60637, USA.
Peev AM; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, 60637, USA.
Swarbrick GM; Division of Infectious Diseases, Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA.
Cansler M; Division of Infectious Diseases, Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA.
Null M; Division of Infectious Diseases, Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA.
Boughter CT; Graduate Program in Biophysical Sciences, University of Chicago, Chicago, IL, 60637, USA.
McMurtrey C; PureMHC LLC, Oklahoma City, OK, 73104, USA.
Nilsen A; Medicinal Chemistry Core, Oregon Health & Science University, Portland, OR, 97239, USA.; VA Portland Health Care System, Portland, OR, 97239, USA.
Dobos KM; Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, 80523, USA.
Hildebrand WH; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Lewinsohn DA; Division of Infectious Diseases, Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA.; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, 97239, USA.
Adams EJ; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, 60637, USA.
Lewinsohn DM; Division of Infectious Diseases, Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA.; VA Portland Health Care System, Portland, OR, 97239, USA.; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, 97239, USA.
Harriff MJ; VA Portland Health Care System, Portland, OR, 97239, USA. .; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, 97239, USA. .; Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, OR, 97239, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 29; Vol. 12 (1), pp. 22539. Date of Electronic Publication: 2022 Dec 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
T-Lymphocytes*
Mucosal-Associated Invariant T Cells*
Ligands ; Histocompatibility Antigens Class I/metabolism ; Molecular Docking Simulation ; Receptors, Antigen, T-Cell/metabolism ; Minor Histocompatibility Antigens/metabolism ; Antigen Presentation
Czasopismo naukowe
Tytuł:
Attention-aware contrastive learning for predicting T cell receptor-antigen binding specificity.
Autorzy:
Fang Y; School of Computer Science and Technology, Nanjing Tech University, 211816, Nanjing, China.
Liu X; School of Computer Science and Technology, Nanjing Tech University, 211816, Nanjing, China.
Liu H; School of Computer Science and Technology, Nanjing Tech University, 211816, Nanjing, China.
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Źródło:
Briefings in bioinformatics [Brief Bioinform] 2022 Nov 19; Vol. 23 (6).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, Antigen, T-Cell*
T-Lymphocytes*
Protein Binding ; Histocompatibility Antigens Class I/metabolism ; HLA Antigens ; Attention ; Amino Acids/metabolism
Czasopismo naukowe
Tytuł:
Human Amnion Epithelial Cells Impair T Cell Proliferation: The Role of HLA-G and HLA-E Molecules.
Autorzy:
Morandi F; Stem Cell Laboratory and Cell Therapy Center, IRCCS Istituto Giannina Gaslini, Via Gaslini5, 16147 Genova, Italy.
Marimpietri D; Stem Cell Laboratory and Cell Therapy Center, IRCCS Istituto Giannina Gaslini, Via Gaslini5, 16147 Genova, Italy.
Görgens A; Department of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institutet, 14157 Stockholm, Sweden.; Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Gallo A; Department of Research, IRCCS ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione), Via E.Tricomi 5, 90127 Palermo, Italy.
Srinivasan RC; Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet, Alfred Nobels Alle 8, Huddinge SE-141 83, 14157 Stockholm, Sweden.
El-Andaloussi S; Department of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institutet, 14157 Stockholm, Sweden.
Gramignoli R; Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet, Alfred Nobels Alle 8, Huddinge SE-141 83, 14157 Stockholm, Sweden.
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Źródło:
Cells [Cells] 2020 Sep 19; Vol. 9 (9). Date of Electronic Publication: 2020 Sep 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amnion/*immunology
Cell Communication/*immunology
Epithelial Cells/*immunology
HLA-G Antigens/*genetics
Histocompatibility Antigens Class I/*genetics
T-Lymphocytes/*immunology
Amnion/cytology ; Antibodies, Monoclonal/pharmacology ; Cell Differentiation ; Cell Proliferation ; Coculture Techniques ; Epithelial Cells/cytology ; Extracellular Vesicles/chemistry ; Extracellular Vesicles/immunology ; Gene Expression Regulation ; HLA-G Antigens/immunology ; Histocompatibility Antigens Class I/immunology ; Humans ; Primary Cell Culture ; T-Lymphocytes/cytology ; beta 2-Microglobulin/antagonists & inhibitors ; beta 2-Microglobulin/genetics ; beta 2-Microglobulin/immunology ; HLA-E Antigens
Czasopismo naukowe
Tytuł:
Tolerogenic Dendritic Cells Induce Apoptosis-Independent T Cell Hyporesponsiveness of SARS-CoV-2-Specific T Cells in an Antigen-Specific Manner.
Autorzy:
Van Delen M; Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Janssens I; Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Dams A; Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Roosens L; Laboratory of Clinical Biology, Antwerp University Hospital, 2650 Edegem, Belgium.
Ogunjimi B; Centre for Health Economics Research & Modeling Infectious Diseases (CHERMID), VAXINFECTIO, University of Antwerp, 2610 Antwerp, Belgium.; Department of Paediatrics, Antwerp University Hospital, 2650 Edegem, Belgium.; Antwerp Center for Translational Immunology and Virology (ACTIV), VAXINFECTIO, University of Antwerp, 2610 Antwerp, Belgium.; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing (AUDACIS), University of Antwerp, 2020 Antwerp, Belgium.
Berneman ZN; Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.; Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, 2650 Edegem, Belgium.
Derdelinckx J; Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.; Department of Neurology, Antwerp University Hospital, 2650 Edegem, Belgium.
Cools N; Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.; Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, 2650 Edegem, Belgium.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 02; Vol. 23 (23). Date of Electronic Publication: 2022 Dec 02.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*
COVID-19*
Humans ; SARS-CoV-2 ; Immune Tolerance ; Dendritic Cells ; Antigens ; Peptides ; Apoptosis
Czasopismo naukowe
Tytuł:
Chimeric Antigen Receptor T Cell Exhaustion during Treatment for Hematological Malignancies.
Autorzy:
Shen C; Biotherapy Center, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.
Zhang Z; Biotherapy Center, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.
Zhang Y; Biotherapy Center, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.; Cancer Center, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.; School of Life Sciences, Zhengzhou University, Zhengzhou 450052, China.; Henan Key Laboratory for Tumor Immunology and Biotherapy, Zhengzhou 450052, China.
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Źródło:
BioMed research international [Biomed Res Int] 2020 Oct 23; Vol. 2020, pp. 8765028. Date of Electronic Publication: 2020 Oct 23 (Print Publication: 2020).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Clonal Anergy*
Antigens, CD19/*genetics
Hematologic Neoplasms/*therapy
Immunotherapy, Adoptive/*methods
Receptors, Chimeric Antigen/*genetics
T-Lymphocytes/*immunology
Antigens, CD19/immunology ; Antigens, Neoplasm/genetics ; Antigens, Neoplasm/immunology ; B7-H1 Antigen/genetics ; B7-H1 Antigen/immunology ; CD28 Antigens/genetics ; CD28 Antigens/immunology ; Gene Expression ; Hematologic Neoplasms/genetics ; Hematologic Neoplasms/immunology ; Hematologic Neoplasms/pathology ; Humans ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/immunology ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/immunology ; Receptors, Chimeric Antigen/immunology ; Recurrence ; T-Lymphocytes/pathology ; Treatment Failure ; Tumor Necrosis Factor Receptor Superfamily, Member 9/genetics ; Tumor Necrosis Factor Receptor Superfamily, Member 9/immunology
Czasopismo naukowe

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