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Tytuł:
Getting more bang for their buck: BCL2 inhibitors boost dendritic-cell function to enhance anti-cancer immune surveillance.
Autorzy:
Montes-Gómez AE; Cancer Research UK Scotland Institute, Switchback Road, Glasgow, G61 1BD, UK. .; School of Cancer Sciences, University of Glasgow, Switchback Road, Glasgow, G61 1BD, UK. .
Tait SWG; Cancer Research UK Scotland Institute, Switchback Road, Glasgow, G61 1BD, UK. .; School of Cancer Sciences, University of Glasgow, Switchback Road, Glasgow, G61 1BD, UK. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Mar 28; Vol. 22 (1), pp. 317. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Letter
MeSH Terms:
Neoplasms*/drug therapy
Neoplasms*/metabolism
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Apoptosis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Apoptosis Regulatory Proteins/pharmacology ; Apoptosis Regulatory Proteins/therapeutic use ; Cell Line, Tumor
Opinia redakcyjna
Tytuł:
A review of the clinical efficacy of FDA-approved antibody‒drug conjugates in human cancers.
Autorzy:
Liu K; Laboratory of Urology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524001, China.; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Li M; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Li Y; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Li Y; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Chen Z; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Tang Y; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Yang M; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Deng G; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Liu H; Laboratory of Urology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524001, China. .; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China. .
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Źródło:
Molecular cancer [Mol Cancer] 2024 Mar 23; Vol. 23 (1), pp. 62. Date of Electronic Publication: 2024 Mar 23.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunoconjugates*/therapeutic use
Neoplasms*/drug therapy
Neoplasms*/pathology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
United States ; Humans ; United States Food and Drug Administration ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Targeting inflammation as cancer therapy.
Autorzy:
Wang M; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No.17, Block3, Southern Renmin Road, Chengdu, 610041, Sichuan, People's Republic of China.
Chen S; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No.17, Block3, Southern Renmin Road, Chengdu, 610041, Sichuan, People's Republic of China.
He X; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No.17, Block3, Southern Renmin Road, Chengdu, 610041, Sichuan, People's Republic of China.
Yuan Y; Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, People's Republic of China. .
Wei X; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No.17, Block3, Southern Renmin Road, Chengdu, 610041, Sichuan, People's Republic of China. .
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Źródło:
Journal of hematology & oncology [J Hematol Oncol] 2024 Mar 22; Vol. 17 (1), pp. 13. Date of Electronic Publication: 2024 Mar 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/pathology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Cytokines/metabolism ; Inflammation/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Advances in AI for Protein Structure Prediction: Implications for Cancer Drug Discovery and Development.
Autorzy:
Qiu X; Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA 92521, USA.
Li H; Department of Computer Science and Engineering, University of California Riverside, Riverside, CA 92521, USA.
Ver Steeg G; Department of Computer Science and Engineering, University of California Riverside, Riverside, CA 92521, USA.
Godzik A; Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA 92521, USA.
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Źródło:
Biomolecules [Biomolecules] 2024 Mar 12; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Neoplasms*/drug therapy
Humans ; Drug Discovery ; Drug Development ; Artificial Intelligence
Czasopismo naukowe
Tytuł:
DeepAEG: a model for predicting cancer drug response based on data enhancement and edge-collaborative update strategies.
Autorzy:
Lao C; Research Center for Graph Computing, Zhejiang Lab, Yuhang, Hangzhou, 311121, Zhejiang, China.
Zheng P; Research Center for Graph Computing, Zhejiang Lab, Yuhang, Hangzhou, 311121, Zhejiang, China.
Chen H; Research Center for Graph Computing, Zhejiang Lab, Yuhang, Hangzhou, 311121, Zhejiang, China. .
Liu Q; Department of Statistics, Stanford University, Stanford, Palo Alto, CA, 94305, USA.
An F; Research Center for Graph Computing, Zhejiang Lab, Yuhang, Hangzhou, 311121, Zhejiang, China.
Li Z; Research Center for Graph Computing, Zhejiang Lab, Yuhang, Hangzhou, 311121, Zhejiang, China.
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2024 Mar 09; Vol. 25 (1), pp. 105. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Neoplasms*/drug therapy
Neoplasms*/genetics
Humans ; Bortezomib ; Genomics ; Uncertainty
Czasopismo naukowe
Tytuł:
Integrating natural compounds and nanoparticle-based drug delivery systems: A novel strategy for enhanced efficacy and selectivity in cancer therapy.
Autorzy:
Manzari-Tavakoli A; Department of biology faculty of science, Ferdowsi University of Mashhad, Mashhad, Iran.
Babajani A; Oncopathology Research Center, Department of Molecular Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Tavakoli MM; Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Tehran, Iran.
Safaeinejad F; Traditional Medicine and Materia Medica Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Jafari A; Chronic Respiratory Diseases Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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Źródło:
Cancer medicine [Cancer Med] 2024 Mar; Vol. 13 (5), pp. e7010.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Neoplasms*/drug therapy
Neoplasms*/metabolism
Nanoparticles*/chemistry
Humans ; Nanoparticle Drug Delivery System ; Drug Delivery Systems
Czasopismo naukowe
Tytuł:
Recent Advances in Structural Optimization of Quinazoline-Based Protein Kinase Inhibitors for Cancer Therapy (2021-Present).
Autorzy:
Abdel-Mohsen HT; Chemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, El-Bohouth Street, Dokki, Cairo P.O. Box 12622, Egypt.
Anwar MM; Department of Therapeutic Chemistry, Pharmaceutical and Drug Industries Research Institute, National Research Centre, El-Bohouth Street, Dokki, Cairo P.O. Box 12622, Egypt.
Ahmed NS; Department of Therapeutic Chemistry, Pharmaceutical and Drug Industries Research Institute, National Research Centre, El-Bohouth Street, Dokki, Cairo P.O. Box 12622, Egypt.
Abd El-Karim SS; Department of Therapeutic Chemistry, Pharmaceutical and Drug Industries Research Institute, National Research Centre, El-Bohouth Street, Dokki, Cairo P.O. Box 12622, Egypt.
Abdelwahed SH; Department of Chemistry, Prairie View A & M University, Prairie View, TX 77446, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 16; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Antineoplastic Agents*/chemistry
Neoplasms*/drug therapy
Neoplasms*/metabolism
Humans ; Quinazolines/pharmacology ; Quinazolines/therapeutic use ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Drug Design ; Protein Kinases/metabolism ; Structure-Activity Relationship ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł:
Unveiling the mechanisms and challenges of cancer drug resistance.
Autorzy:
Khan SU; Division of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Holcombe Blvd, Houston, TX, 77030, USA. .; Division of Cancer Pharmacology, CSIR-Indian Institute of Integrative Medicine, Srinagar-190005, Jammu and Kashmir, India. .; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India. .
Fatima K; Division of Cancer Pharmacology, CSIR-Indian Institute of Integrative Medicine, Srinagar-190005, Jammu and Kashmir, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.
Aisha S; Division of Cancer Pharmacology, CSIR-Indian Institute of Integrative Medicine, Srinagar-190005, Jammu and Kashmir, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.
Malik F; Division of Cancer Pharmacology, CSIR-Indian Institute of Integrative Medicine, Srinagar-190005, Jammu and Kashmir, India. .; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Feb 12; Vol. 22 (1), pp. 109. Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:
Video-Audio Media; Journal Article; Review
MeSH Terms:
Neoplasms*/drug therapy
Neoplasms*/genetics
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Proteomics ; Drug Resistance, Neoplasm/genetics
Czasopismo naukowe
Tytuł:
Inhibitors of NAD Production in Cancer Treatment: State of the Art and Perspectives.
Autorzy:
Ghanem MS; Department of Internal Medicine and Medical Specialties (DIMI), University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy.
Caffa I; Department of Internal Medicine and Medical Specialties (DIMI), University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy.; Ospedale Policlinico San Martino IRCCS, Largo Rosanna Benzi 10, 16132 Genova, Italy.
Monacelli F; Department of Internal Medicine and Medical Specialties (DIMI), University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy.; Ospedale Policlinico San Martino IRCCS, Largo Rosanna Benzi 10, 16132 Genova, Italy.
Nencioni A; Department of Internal Medicine and Medical Specialties (DIMI), University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy.; Ospedale Policlinico San Martino IRCCS, Largo Rosanna Benzi 10, 16132 Genova, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 08; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/drug therapy
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Niacin*
Humans ; NAD/metabolism ; Nicotinamide Phosphoribosyltransferase/metabolism ; Niacinamide/pharmacology ; Niacinamide/therapeutic use ; Niacinamide/metabolism ; Cytokines/metabolism
Czasopismo naukowe
Tytuł:
Molecular Targeting of the Phosphoinositide-3-Protein Kinase (PI3K) Pathway across Various Cancers.
Autorzy:
Shan KS; Division of Hematology and Oncology, Memorial Health Care, Pembroke Pines, FL 33028, USA.
Bonano-Rios A; Division of Hematology and Oncology, Memorial Health Care, Pembroke Pines, FL 33028, USA.
Theik NWY; Division of Internal Medicine, Memorial Health Care, Pembroke Pines, FL 33028, USA.
Hussein A; Division of Hematology and Oncology, Memorial Health Care, Pembroke Pines, FL 33028, USA.
Blaya M; Division of Hematology and Oncology, Memorial Health Care, Pembroke Pines, FL 33028, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 06; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 06.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/drug therapy
Neoplasms*/chemically induced
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Phosphatidylinositol 3-Kinase/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Molecular Targeted Therapy ; Proto-Oncogene Proteins c-akt/metabolism ; Phosphoinositide-3 Kinase Inhibitors/therapeutic use ; Protein Kinase Inhibitors/adverse effects ; Carcinogenesis/chemically induced ; Phosphatidylinositols/therapeutic use
Czasopismo naukowe
Tytuł:
Oxime-Linked Peptide-Daunomycin Conjugates as Good Tools for Selection of Suitable Homing Devices in Targeted Tumor Therapy: An Overview.
Autorzy:
Mező G; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117 Budapest, Hungary.; Institute of Chemistry, ELTE, Eötvös Loránd University, 1117 Budapest, Hungary.
Gomena J; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117 Budapest, Hungary.; Institute of Chemistry, ELTE, Eötvös Loránd University, 1117 Budapest, Hungary.
Ranđelović I; Department of Experimental Pharmacology and the National Tumor Biology Laboratory, National Institute of Oncology, 1122 Budapest, Hungary.
Dókus EL; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117 Budapest, Hungary.
Kiss K; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117 Budapest, Hungary.; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1111 Budapest, Hungary.
Pethő L; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117 Budapest, Hungary.
Schuster S; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117 Budapest, Hungary.; Institute of Chemistry, ELTE, Eötvös Loránd University, 1117 Budapest, Hungary.
Vári B; Department of Experimental Pharmacology and the National Tumor Biology Laboratory, National Institute of Oncology, 1122 Budapest, Hungary.; School of Ph.D. Studies, Doctoral School of Pathological Sciences, Semmelweis University, 1085 Budapest, Hungary.
Vári-Mező D; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117 Budapest, Hungary.; Department of Experimental Pharmacology and the National Tumor Biology Laboratory, National Institute of Oncology, 1122 Budapest, Hungary.; School of Ph.D. Studies, Doctoral School of Pathological Sciences, Semmelweis University, 1085 Budapest, Hungary.
Lajkó E; Department of Genetics, Cell- and Immunobiology, Semmelweis University, 1089 Budapest, Hungary.
Polgár L; Department of Genetics, Cell- and Immunobiology, Semmelweis University, 1089 Budapest, Hungary.
Kőhidai L; Department of Genetics, Cell- and Immunobiology, Semmelweis University, 1089 Budapest, Hungary.
Tóvári J; Department of Experimental Pharmacology and the National Tumor Biology Laboratory, National Institute of Oncology, 1122 Budapest, Hungary.; School of Ph.D. Studies, Doctoral School of Pathological Sciences, Semmelweis University, 1085 Budapest, Hungary.
Szabó I; HUN-REN-ELTE Research Group of Peptide Chemistry, 1117 Budapest, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 03; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Neoplasms*/drug therapy
Neoplasms*/metabolism
Humans ; Daunorubicin/therapeutic use ; Oximes/therapeutic use ; Peptides/chemistry ; Drug Delivery Systems/methods ; Pharmaceutical Preparations/metabolism
Czasopismo naukowe
Tytuł:
Tumor microenvironment reprogramming combined with immunogenic enhancement by nanoemulsions potentiates immunotherapy.
Autorzy:
Shen W; Department of General Surgery, Second Affiliated Hospital of Soochow University, Suzhou, 215004, P. R. China.; Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221002, Jiangsu, China.; CAS Key Laboratory for Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, P. R. China.
Li Y; Department of General Surgery, Second Affiliated Hospital of Soochow University, Suzhou, 215004, P. R. China.; CAS Key Laboratory for Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, P. R. China.
Yang Z; CAS Key Laboratory for Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, P. R. China.
Li W; CAS Key Laboratory for Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, P. R. China.
Cao Y; CAS Key Laboratory for Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, P. R. China.
Liu Y; School of Intelligent Finance and Business, Entrepreneur College, Xi'an Jiaotong-Liverpool University, Suzhou, 215123, P. R. China.
Wang Z; CAS Key Laboratory for Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, P. R. China. .
Pei R; CAS Key Laboratory for Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, P. R. China. .
Xing C; Department of General Surgery, Second Affiliated Hospital of Soochow University, Suzhou, 215004, P. R. China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Apr 05; Vol. 22 (1), pp. 154. Date of Electronic Publication: 2024 Apr 05.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Neoplasms*/drug therapy
Colorectal Neoplasms*
Humans ; Tumor Microenvironment ; Immune Checkpoint Inhibitors/pharmacology ; Immunotherapy ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Labdane-Type Diterpenoids from Streptomyces griseorubens and Their Antimicrobial and Cytotoxic Activities.
Autorzy:
Heo CS; Marine Natural Products Chemistry Laboratory, Korea Institute of Ocean Science and Technology, 385 Haeyang-ro, Yeongdo-gu, Busan 49111, Republic of Korea.; Department of Marine Technology and Convergence Engineering, Korea National University of Science and Technology (UST), 217 Gajungro, Yuseong-gu, Daejeon 34113, Republic of Korea.
Kang JS; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, 30 Yeongudanjiro, Cheongju 28116, Republic of Korea.
Yang JW; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, 30 Yeongudanjiro, Cheongju 28116, Republic of Korea.
Lee MA; Marine Natural Products Chemistry Laboratory, Korea Institute of Ocean Science and Technology, 385 Haeyang-ro, Yeongdo-gu, Busan 49111, Republic of Korea.; Department of Chemistry, Pukyong National University, 45 Yongso-ro, Nam-gu, Busan 48513, Republic of Korea.
Lee HS; Marine Natural Products Chemistry Laboratory, Korea Institute of Ocean Science and Technology, 385 Haeyang-ro, Yeongdo-gu, Busan 49111, Republic of Korea.; Department of Chemistry, Pukyong National University, 45 Yongso-ro, Nam-gu, Busan 48513, Republic of Korea.
Shin HJ; Marine Natural Products Chemistry Laboratory, Korea Institute of Ocean Science and Technology, 385 Haeyang-ro, Yeongdo-gu, Busan 49111, Republic of Korea.; Department of Marine Technology and Convergence Engineering, Korea National University of Science and Technology (UST), 217 Gajungro, Yuseong-gu, Daejeon 34113, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 14; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Infective Agents*/pharmacology
Anti-Infective Agents*/therapeutic use
Antineoplastic Agents*/therapeutic use
Diterpenes*/chemistry
Neoplasms*/drug therapy
Hematologic Neoplasms*
Streptomyces*
Humans
SCR Organism:
Streptomyces griseorubens
Czasopismo naukowe
Tytuł:
Navigating the Nexus: HIV and Breast Cancer-A Critical Review.
Autorzy:
Marino A; Unit of Infectious Diseases, Department of Clinical and Experimental Medicine, ARNAS Garibaldi Hospital, University of Catania, 95123 Catania, Italy.
Pavone G; Medical Oncology Unit, Humanitas Istituto Clinico Catanese, 95045 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Martorana F; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Fisicaro V; Department of Clinical and Experimental Medicine, University of Messina, 98124 Messina, Italy.
Motta L; Medical Oncology Unit, Humanitas Istituto Clinico Catanese, 95045 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Spampinato S; Department of Clinical and Experimental Medicine, University of Messina, 98124 Messina, Italy.
Celesia BM; Unit of Infectious Diseases, Department of Clinical and Experimental Medicine, ARNAS Garibaldi Hospital, University of Catania, 95123 Catania, Italy.
Cacopardo B; Unit of Infectious Diseases, Department of Clinical and Experimental Medicine, ARNAS Garibaldi Hospital, University of Catania, 95123 Catania, Italy.
Vigneri P; Medical Oncology Unit, Humanitas Istituto Clinico Catanese, 95045 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Nunnari G; Unit of Infectious Diseases, Department of Clinical and Experimental Medicine, ARNAS Garibaldi Hospital, University of Catania, 95123 Catania, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 12; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV Infections*/complications
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Breast Neoplasms*/epidemiology
Breast Neoplasms*/etiology
Breast Neoplasms*/drug therapy
Neoplasms*/drug therapy
Antineoplastic Agents*/therapeutic use
Humans ; Female ; Immunosuppression Therapy
Czasopismo naukowe
Tytuł:
Shifting the paradigm: engaging multicellular networks for cancer therapy.
Autorzy:
Hu J; Sonata Therapeutics, Watertown, MA, 02472, USA. .
Ascierto P; Cancer Immunotherapy and Innovative Therapy, National Tumor Institute, Fondazione G. Pascale, 80131, Naples, Italy.
Cesano A; ESSA Pharmaceuticals, South San Francisco, CA, 94080, USA.
Herrmann V; Sonata Therapeutics, Watertown, MA, 02472, USA.
Marincola FM; Sonata Therapeutics, Watertown, MA, 02472, USA. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Mar 12; Vol. 22 (1), pp. 270. Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/therapy
Antineoplastic Agents*/therapeutic use
Humans ; Cytokines/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Bacterial DnaK reduces the activity of anti-cancer drugs cisplatin and 5FU.
Autorzy:
Benedetti F; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA.
Mongodin EF; Department of Microbiology and Immunology, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Badger JH; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD, USA.
Munawwar A; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Cellini A; Pathology Biorepository Shared Service, University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, 21201, USA.
Yuan W; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Silvestri G; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Kraus CN; Aquestive, Warren, NJ, USA.
Marini S; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.; Department of Epidemiology, University of Florida, Gainesville, FL, USA.
Rathinam CV; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Salemi M; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.; Department of Pathology, University of Florida, Gainesville, FL, USA.
Tettelin H; Department of Microbiology and Immunology, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Gallo RC; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA. .; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. .
Zella D; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA. .; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Mar 12; Vol. 22 (1), pp. 269. Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*
Neoplasms*
Animals ; Mice ; Humans ; Cisplatin ; Tumor Suppressor Protein p53 ; Fluorouracil ; Bacteria
Czasopismo naukowe
Tytuł:
Zeolitic Imidazole Framework/Silica Nanocomposite for Targeted Cancer Therapeutics: Comparative Study of Chemo-Drug Cisplatin (CPt) and Green Platinum (GPt) Efficacy.
Autorzy:
Alotaibi HG; Renewable Energy Unit, Basic & Applied Scientific Research Center (BASRC), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.; Department of Chemistry, Collage of Science, Imam Muhammad Bin Saud Islamic University, Riyadh 31441, Saudi Arabia.; Department of Nanomedicine Research, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Al-Abbad E; Renewable Energy Unit, Basic & Applied Scientific Research Center (BASRC), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.; Department of Chemistry, College of Science, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Almohazey D; Department of Stem Cell Research, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Ravinayagam V; Deanship of Scientific Research & Department of Nanomedicine Research, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Akhtar S; Department of Biophysics Research, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Dafalla H; College of Engineering Research (CER), King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia.
Jermy BR; Department of Nanomedicine Research, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 09; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Zeolites*/chemistry
Antineoplastic Agents*/pharmacology
Nanocomposites*
Neoplasms*/drug therapy
Humans ; Cisplatin/pharmacology ; Platinum ; Spectroscopy, Fourier Transform Infrared ; Silicon Dioxide/chemistry ; Imidazoles/pharmacology ; Imidazoles/chemistry
Czasopismo naukowe
Tytuł:
Design, Synthesis, Biological Evaluation and Molecular Docking of Novel F-18-Labeled Focal Adhesion Kinase Inhibitors as Potential Tumor Radiotracers.
Autorzy:
Yang H; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, No. 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China.
Li Y; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, No. 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China.
Liang H; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, No. 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China.
Cui C; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, No. 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China.
Gan L; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, No. 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China.
Zhang H; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, No. 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Mar 08; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 08.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/diagnostic imaging
Neoplasms*/drug therapy
Antineoplastic Agents*/chemistry
Mice ; Animals ; Focal Adhesion Protein-Tyrosine Kinases ; Molecular Docking Simulation ; Radiopharmaceuticals/chemistry ; Biological Transport ; Protein Kinase Inhibitors/chemistry ; Cell Line, Tumor ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Retrospective analysis of real-world prescribing data for managing cisplatin-based chemotherapy-induced nausea and vomiting in China.
Autorzy:
Si X; Department of Pharmacy, Peking University People's Hospital, Beijing, China.
Zhang H; Orthopedic Oncology, Peking University People's Hospital, Beijing, China.
Ding Q; Department of Pharmacy, Peking University People's Hospital, Beijing, China.
Liu G; Department of Pharmacy, Peking University People's Hospital, Beijing, China.
Huang L; Department of Pharmacy, Peking University People's Hospital, Beijing, China.
Sun X; Orthopedic Oncology, Peking University People's Hospital, Beijing, China.
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Źródło:
Cancer medicine [Cancer Med] 2024 Mar; Vol. 13 (6), pp. e7121.
Typ publikacji:
Journal Article
MeSH Terms:
Antiemetics*/therapeutic use
Antineoplastic Agents*/adverse effects
Neoplasms*/drug therapy
Humans ; Cisplatin/adverse effects ; Retrospective Studies ; Serotonin/adverse effects ; Vomiting/chemically induced ; Vomiting/drug therapy ; Nausea/chemically induced ; Nausea/drug therapy
Czasopismo naukowe
Tytuł:
Dualistic Effects of PRKAR1A as a Potential Anticancer Target in Cancer Cells and Cancer-Derived Stem Cells.
Autorzy:
Baek JW; Department of Biomedical Laboratory Science, Konyang University, Daejeon 35365, Republic of Korea.
Nam AR; Department of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.
Kim K; Department of Convergence Medicine, Asan Medical Center, Seoul 05505, Republic of Korea.
Kim PH; Department of Biomedical Laboratory Science, Konyang University, Daejeon 35365, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 01; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Neoplasms*/metabolism
Humans ; Cell Line, Tumor ; Proteomics ; Biomarkers/metabolism ; Transcription Factors/metabolism ; Neoplastic Stem Cells/metabolism ; Epithelial-Mesenchymal Transition ; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit/metabolism
Czasopismo naukowe

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