Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""APOPTOSIS"" wg kryterium: Temat


Starter badań:

Tytuł:
XAF1 overexpression exacerbates diabetes by promoting pancreatic β-cell apoptosis.
Autorzy:
Nishimura Y; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Iwashita M; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. .
Hayashi M; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Shinjo T; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Watanabe Y; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Zeze T; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Yamashita A; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Fukuda T; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Sanui T; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Sano T; Department of Cell Biology and Pharmacology, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.
Asano T; Department of Medical Chemistry, Division of Molecular Medical Science, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Nishimura F; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Pokaż więcej
Źródło:
Acta diabetologica [Acta Diabetol] 2022 Oct; Vol. 59 (10), pp. 1275-1286. Date of Electronic Publication: 2022 Jul 13.
Typ publikacji:
Journal Article
MeSH Terms:
Adaptor Proteins, Signal Transducing*/genetics
Apoptosis Regulatory Proteins*/genetics
Diabetes Mellitus, Type 2*/genetics
Diabetes Mellitus, Type 2*/metabolism
Insulin-Secreting Cells*/metabolism
Islets of Langerhans*/metabolism
Animals ; Apoptosis/genetics ; Diet, High-Fat/adverse effects ; Insulin/metabolism ; Insulin Secretion ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
XIAP as a multifaceted molecule in Cellular Signaling.
Autorzy:
Hanifeh M; Department of Biochemistry, Faculty of Biological Sciences, Trabiat Modares University, Tehran, Iran.
Ataei F; Department of Biochemistry, Faculty of Biological Sciences, Trabiat Modares University, Tehran, Iran. ataei_.
Pokaż więcej
Źródło:
Apoptosis : an international journal on programmed cell death [Apoptosis] 2022 Aug; Vol. 27 (7-8), pp. 441-453. Date of Electronic Publication: 2022 Jun 04.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
X-Linked Inhibitor of Apoptosis Protein*/genetics
Caspases/metabolism ; Cell Death ; Inhibitor of Apoptosis Proteins
Czasopismo naukowe
Tytuł:
Structural and biochemical analyses of Bcl-xL in complex with the BH3 domain of peroxisomal testis-specific 1.
Autorzy:
Lim D; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea; Department of Biochemistry, Chungnam National University, Daejeon, 34134, South Korea.
Jin S; Department of Biochemistry, Chungnam National University, Daejeon, 34134, South Korea; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea.
Shin HC; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea.
Kim W; Department of Biochemistry, Chungnam National University, Daejeon, 34134, South Korea.
Choi JS; Department of Biochemistry, Chungnam National University, Daejeon, 34134, South Korea.
Oh DB; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea; Department of Biosystems and Bioengineering, KRIBB School of Biotechnology, University of Science and Technology, Daejeon, 34113, South Korea.
Kim SJ; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea; Department of Proteome Structural Biology, KRIBB School of Bioscience, University of Science and Technology, Daejeon, 34113, South Korea. Electronic address: .
Seo J; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea. Electronic address: .
Ku B; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea. Electronic address: .
Pokaż więcej
Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Oct 15; Vol. 625, pp. 174-180. Date of Electronic Publication: 2022 Aug 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis Regulatory Proteins*/metabolism
Testis*/metabolism
Amino Acid Sequence ; Amino Acids/metabolism ; Animals ; Apoptosis ; HeLa Cells ; Humans ; Male ; Mice ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-X Protein/metabolism
Czasopismo naukowe
Tytuł:
Solution structure of c-FLIP death effector domains.
Autorzy:
Bai ZQ; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132 Lanhei Road, Heilongtan, Kunming, 650201, Yunnan, China; Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Ma X; Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Liu B; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132 Lanhei Road, Heilongtan, Kunming, 650201, Yunnan, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Huang T; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132 Lanhei Road, Heilongtan, Kunming, 650201, Yunnan, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Hu K; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132 Lanhei Road, Heilongtan, Kunming, 650201, Yunnan, China; Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. Electronic address: .
Pokaż więcej
Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Aug 30; Vol. 617 (Pt 2), pp. 1-6. Date of Electronic Publication: 2022 May 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CASP8 and FADD-Like Apoptosis Regulating Protein*/metabolism
Death Effector Domain*
Apoptosis ; Caspase 8/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
ARTS, an unusual septin, regulates tumorigenesis by promoting apoptosis.
Autorzy:
Bian C; Jilin Provincial Key Laboratory of Radiation Oncology & Therapy, The First Hospital of Jilin University, Changchun 130021, China; Department of Radiation Oncology, The First Hospital of Jilin University, Changchun 130021, China; NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Changchun 130021, China. Electronic address: .
Su J; Jilin Provincial Key Laboratory of Radiation Oncology & Therapy, The First Hospital of Jilin University, Changchun 130021, China; Department of Radiation Oncology, The First Hospital of Jilin University, Changchun 130021, China; NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Changchun 130021, China. Electronic address: .
Zheng Z; Jilin Provincial Key Laboratory of Radiation Oncology & Therapy, The First Hospital of Jilin University, Changchun 130021, China; Department of Radiation Oncology, The First Hospital of Jilin University, Changchun 130021, China; NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Changchun 130021, China. Electronic address: .
Wei J; Jilin Provincial Key Laboratory of Radiation Oncology & Therapy, The First Hospital of Jilin University, Changchun 130021, China; Department of Radiation Oncology, The First Hospital of Jilin University, Changchun 130021, China; NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Changchun 130021, China. Electronic address: .
Wang H; Jilin Provincial Key Laboratory of Radiation Oncology & Therapy, The First Hospital of Jilin University, Changchun 130021, China; Department of Radiation Oncology, The First Hospital of Jilin University, Changchun 130021, China; NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Changchun 130021, China. Electronic address: .
Meng L; Department of Hematology and Medical Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA. Electronic address: .
Xin Y; Key Laboratory of Pathobiology, Ministry of Education, Jilin University, Changchun 130021, China. Electronic address: .
Jiang X; Jilin Provincial Key Laboratory of Radiation Oncology & Therapy, The First Hospital of Jilin University, Changchun 130021, China; Department of Radiation Oncology, The First Hospital of Jilin University, Changchun 130021, China; NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Changchun 130021, China. Electronic address: .
Pokaż więcej
Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Aug; Vol. 152, pp. 113281. Date of Electronic Publication: 2022 Jun 14.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Apoptosis*/physiology
Septins*/genetics
Septins*/metabolism
Carcinogenesis/metabolism ; Cell Transformation, Neoplastic/metabolism ; Humans ; Inhibitor of Apoptosis Proteins/genetics ; Mitochondria/metabolism
Czasopismo naukowe
Tytuł:
BID- and BAX-mediated mitochondrial pathway dominates A-1331852-induced apoptosis in senescent A549 cells.
Autorzy:
Wu G; Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Li X; Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Zhan Y; Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Fan X; Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Xu L; Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Chen T; MOE Key Laboratory of Laser Life Science & Guangdong Provincial Key Laboratory of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou, 510631, China.
Wang X; Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. Electronic address: .
Pokaż więcej
Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Oct 30; Vol. 627, pp. 160-167. Date of Electronic Publication: 2022 Aug 18.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Mitochondria*/metabolism
BH3 Interacting Domain Death Agonist Protein/*metabolism
A549 Cells ; Apoptosis Regulatory Proteins/metabolism ; Benzothiazoles ; Humans ; Isoquinolines ; Poly(ADP-ribose) Polymerases/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-2-Associated X Protein/metabolism ; bcl-X Protein/metabolism
Czasopismo naukowe
Tytuł:
IAP antagonist GDC-0917 is more potent than Debio1143 in promoting cell death, c-IAP1 degradation and tumor growth inhibition.
Autorzy:
Alicke B; Departments of In Vivo Pharmacology, Genentech, South San Francisco, CA, 94110, USA.
Varfolomeev E; Immunology Discovery, Genentech, South San Francisco, CA, 94110, USA.; Early Discovery Biochemistry, Genentech, South San Francisco, CA, 94110, USA.
Lee SHK; Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA, 94110, USA.
Frommlet A; Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA, 94110, USA.
Ubhayakar S; Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA, 94110, USA.
Quinn JG; Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA, 94110, USA.
Fairbrother WJ; Early Discovery Biochemistry, Genentech, South San Francisco, CA, 94110, USA.
Jones R; Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA, 94110, USA.
Gould SE; Departments of In Vivo Pharmacology, Genentech, South San Francisco, CA, 94110, USA.
Vucic D; Immunology Discovery, Genentech, South San Francisco, CA, 94110, USA. .; Early Discovery Biochemistry, Genentech, South San Francisco, CA, 94110, USA. .
Pokaż więcej
Źródło:
Cell death & disease [Cell Death Dis] 2022 Sep 28; Vol. 13 (9), pp. 831. Date of Electronic Publication: 2022 Sep 28.
Typ publikacji:
Journal Article
MeSH Terms:
Inhibitor of Apoptosis Proteins*/metabolism
Neoplasms*/drug therapy
Apoptosis ; Cell Death ; Humans
Czasopismo naukowe
Tytuł:
Biochemical characterization of a disease-causing human osteoprotegerin variant.
Autorzy:
Luo Y; Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, SUNY, Buffalo, NY 14214, USA.
Li M; Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, SUNY, Buffalo, NY 14214, USA.
Xu D; Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, SUNY, Buffalo, NY 14214, USA. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2022 Sep 10; Vol. 12 (1), pp. 15279. Date of Electronic Publication: 2022 Sep 10.
Typ publikacji:
Journal Article
MeSH Terms:
TNF-Related Apoptosis-Inducing Ligand*/metabolism
Osteoprotegerin/*chemistry
Apoptosis ; Chondrocytes/metabolism ; Heparitin Sulfate/metabolism ; Humans ; Osteoprotegerin/genetics ; Osteoprotegerin/metabolism
Czasopismo naukowe
Tytuł:
Chloroquine alleviates the heat-induced to injure via autophagy and apoptosis mechanisms in skin cell and mouse models.
Autorzy:
Tang SC; Department of Nursing, National Taichung University of Science and Technology, Taichung, Taiwan.
Ko JL; Department of Medical Oncology and Chest Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.; Institute of Medicine, School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Lu CT; Division of Plastic and Reconstructive Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan.; Institute of Medicine, School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Leong PY; Institute of Medicine, School of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Rheumatology, Chung Shan Medical University Hospital, Taichung, Taiwan.
Ou CC; Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan.; Department of Nutrition, Chung Shan Medical University Hospital, Taichung, Taiwan.
Hsu CT; Institute of Medicine, School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Hsiao YP; Institute of Medicine, School of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Dermatology, Chung Shan Medical University Hospital, Taichung, Taiwan.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2022 Aug 31; Vol. 17 (8), pp. e0272797. Date of Electronic Publication: 2022 Aug 31 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/drug effects
Autophagy*/drug effects
Burns*/drug therapy
Chloroquine*/metabolism
Chloroquine*/pharmacology
Animals ; Apoptosis Regulatory Proteins ; Disease Models, Animal ; Hot Temperature ; Humans ; Mice ; Rats ; Wnt3A Protein/metabolism ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł:
Identification of Circular RNA circ_0017068 as a Regulator of Proliferation and Apoptosis in Trophoblast Cells by miR-330-5p/XIAP Axis.
Autorzy:
Wang W; Department of Gynaecology, Shaanxi Provincial People's Hospital, No. 256 Youyi West Road, Xi'an 710068, Shaanxi Province, China. .
Shi J; Department of Gynaecology, Shaanxi Provincial People's Hospital, No. 256 Youyi West Road, Xi'an 710068, Shaanxi Province, China.
Zheng L; College of Pharmacy, Xi'an Medical University, Xi'an City, Shaanxi Province, China.
Pokaż więcej
Źródło:
Reproductive sciences (Thousand Oaks, Calif.) [Reprod Sci] 2022 Aug; Vol. 29 (8), pp. 2414-2427. Date of Electronic Publication: 2022 Jan 03.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
Pre-Eclampsia*
RNA, Circular*/genetics
X-Linked Inhibitor of Apoptosis Protein*/genetics
Apoptosis ; Cell Proliferation ; Female ; Humans ; Placenta/metabolism ; Pregnancy ; Trophoblasts/metabolism
Czasopismo naukowe
Tytuł:
OSI-027 inhibits the tumorigenesis of colon cancer through mediation of c-Myc/FOXO3a/PUMA axis.
Autorzy:
Lou J; Department of Gastroenterology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.; Department of Gastroenterology, HwaMei Hospital, University of Chinese Academy of Sciences, Ningbo, Zhejiang, China.
Lv JX; Department of Gastroenterology, HwaMei Hospital, University of Chinese Academy of Sciences, Ningbo, Zhejiang, China.
Zhang YP; Department of Gastroenterology, HwaMei Hospital, University of Chinese Academy of Sciences, Ningbo, Zhejiang, China.
Liu ZJ; Department of Gastroenterology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Pokaż więcej
Źródło:
Cell biology international [Cell Biol Int] 2022 Aug; Vol. 46 (8), pp. 1204-1214. Date of Electronic Publication: 2022 Jun 08.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis Regulatory Proteins*/metabolism
Colonic Neoplasms*/metabolism
Apoptosis ; Carcinogenesis ; Cell Line, Tumor ; Cell Transformation, Neoplastic ; Forkhead Box Protein O3/metabolism ; Forkhead Transcription Factors/metabolism ; Humans ; Imidazoles ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; TOR Serine-Threonine Kinases ; Triazines
Czasopismo naukowe
Tytuł:
Cytoprotective effect of genistein against dexamethasone-induced pancreatic β-cell apoptosis.
Autorzy:
Suksri K; Division of Endocrinology, Department of Physiology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.
Semprasert N; Division of Endocrinology, Department of Physiology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.
Limjindaporn T; Department of Anatomy, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Yenchitsomanus PT; Division of Molecular Medicine, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kooptiwoot S; Department of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kooptiwut S; Division of Endocrinology, Department of Physiology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand. S_.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2022 Jul 28; Vol. 12 (1), pp. 12950. Date of Electronic Publication: 2022 Jul 28.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism
TNF-Related Apoptosis-Inducing Ligand*/pharmacology
Animals ; Apoptosis ; Apoptosis Regulatory Proteins/metabolism ; Caspase 3/metabolism ; Caspase 8/metabolism ; Cell Line, Tumor ; Dexamethasone/adverse effects ; Genistein/pharmacology ; Mice ; NF-kappa B/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Rats ; Superoxides/metabolism ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
Induction of DR5-Dependent Apoptosis by PGA 2 through ATF4-CHOP Pathway.
Autorzy:
Park KM; Department of Biomedicine and Health Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.; Department of Biochemistry, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Park JY; Department of Biomedicine and Health Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.; Department of Biochemistry, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Pyo J; Department of Biomedicine and Health Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.; Department of Biochemistry, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Lee SY; Department of Biomedicine and Health Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.; Cancer Evolution Research Center, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Kim HS; Department of Biomedicine and Health Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.; Department of Biochemistry, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.; Cancer Evolution Research Center, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Jun 13; Vol. 27 (12). Date of Electronic Publication: 2022 Jun 13.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, TNF-Related Apoptosis-Inducing Ligand*/genetics
Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism
Activating Transcription Factor 4/genetics ; Activating Transcription Factor 4/metabolism ; Apoptosis ; Cell Line, Tumor ; HCT116 Cells ; Humans ; Prostaglandins A ; RNA, Messenger ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; Transcription Factor CHOP/genetics ; Transcription Factor CHOP/metabolism ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł:
XIAP promotes melanoma growth by inducing tumour neutrophil infiltration.
Autorzy:
Daoud M; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Broxtermann PN; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Schorn F; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Werthenbach JP; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Seeger JM; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Schiffmann LM; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital of Cologne, Department of General, Visceral, Cancer and Transplant Surgery, University of Cologne, Cologne, Germany.
Brinkmann K; The Walter & Eliza Hall Institute of Medical Research (WEHI) and Department of Medical Biology, University of Melbourne, Melbourne, Vic., Australia.
Vucic D; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA, USA.
Tüting T; Laboratory of Experimental Dermatology, Department of Dermatology, University Hospital Magdeburg, Magdeburg, Germany.
Mauch C; Faculty of Medicine and University Hospital of Cologne, Department of Dermatology and Venereology, University of Cologne, Cologne, Germany.
Kulms D; Department of Dermatology, Experimental Dermatology, TU-Dresden, Dresden, Germany.; National Center for Tumor Diseases Dresden, TU-Dresden, Dresden, Germany.
Zigrino P; Faculty of Medicine and University Hospital of Cologne, Department of Dermatology and Venereology, University of Cologne, Cologne, Germany.
Kashkar H; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Pokaż więcej
Źródło:
EMBO reports [EMBO Rep] 2022 Jun 07; Vol. 23 (6), pp. e53608. Date of Electronic Publication: 2022 Apr 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Inhibitor of Apoptosis Proteins*/genetics
Inhibitor of Apoptosis Proteins*/immunology
Melanoma*/genetics
Melanoma*/immunology
Neutrophil Infiltration*/genetics
Neutrophil Infiltration*/immunology
Skin Neoplasms*/genetics
Skin Neoplasms*/immunology
X-Linked Inhibitor of Apoptosis Protein*/genetics
X-Linked Inhibitor of Apoptosis Protein*/immunology
X-Linked Inhibitor of Apoptosis Protein*/metabolism
Adaptor Proteins, Signal Transducing/immunology ; Animals ; Apoptosis/genetics ; Apoptosis/immunology ; Disease Models, Animal ; Humans ; Interleukin-8/biosynthesis ; Mice ; Receptor-Interacting Protein Serine-Threonine Kinase 2/immunology
Czasopismo naukowe
Tytuł:
Expression levels of cellular inhibitor of apoptosis proteins and colitogenic cytokines are inversely correlated with the activation of interferon regulatory factor 4.
Autorzy:
Masaki S; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Watanabe T; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Arai Y; Department of Hematology and Oncology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Sekai I; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Hara A; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Kurimoto M; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Otsuka Y; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Masuta Y; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Yoshikawa T; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Takada R; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Kamata K; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Minaga K; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Yamashita K; Department of Hematology and Oncology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kudo M; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Pokaż więcej
Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2022 May 12; Vol. 207 (3), pp. 340-350.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytokines*/metabolism
Inhibitor of Apoptosis Proteins*/genetics
Inhibitor of Apoptosis Proteins*/metabolism
Inhibitor of Apoptosis Proteins*/pharmacology
Interferon Regulatory Factors/*metabolism
Animals ; Apoptosis ; Humans ; Interferon Regulatory Factors/genetics ; Ligands ; Mice ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
BCL-2-family protein tBID can act as a BAX-like effector of apoptosis.
Autorzy:
Flores-Romero H; Institute for Genetics, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.
Hohorst L; Institute for Genetics, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
John M; Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.
Albert MC; Institute for Molecular Immunology, and Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine, University Hospital of Cologne, University of Cologne, Cologne, Germany.
King LE; Institute for Genetics, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Beckmann L; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany.; Center of Integrated Oncology ABCD, University Hospital of Cologne, Cologne, Germany.
Szabo T; Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Hertlein V; Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.
Luo X; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, ME, USA.; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Villunger A; Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.
Frenzel LP; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany.; Center of Integrated Oncology ABCD, University Hospital of Cologne, Cologne, Germany.
Kashkar H; Institute for Molecular Immunology, and Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine, University Hospital of Cologne, University of Cologne, Cologne, Germany.
Garcia-Saez AJ; Institute for Genetics, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.
Pokaż więcej
Źródło:
The EMBO journal [EMBO J] 2022 Dec 17; Vol. 41 (2), pp. e108690. Date of Electronic Publication: 2021 Dec 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
BH3 Interacting Domain Death Agonist Protein/*metabolism
Apoptosis Regulatory Proteins/metabolism ; BH3 Interacting Domain Death Agonist Protein/chemistry ; BH3 Interacting Domain Death Agonist Protein/genetics ; HCT116 Cells ; HeLa Cells ; Humans ; Mitochondria/metabolism ; Mitochondrial Proteins/metabolism ; Protein Domains ; Proteolysis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-2 Homologous Antagonist-Killer Protein/metabolism ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
Expression, purification, and characterization of c-FLIP tandem death effector domains from Escherichia coli.
Autorzy:
Bai ZQ; Innovative Institute of Chinese Medicine and Pharmacy, University of Traditional Chinese Medicine, Chengdu, 611137, China; College of Science, Yunnan Agricultural University, Kunming, 650201, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
Hu K; Innovative Institute of Chinese Medicine and Pharmacy, University of Traditional Chinese Medicine, Chengdu, 611137, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China. Electronic address: .
Pokaż więcej
Źródło:
Protein expression and purification [Protein Expr Purif] 2022 Dec; Vol. 200, pp. 106168. Date of Electronic Publication: 2022 Sep 06.
Typ publikacji:
Journal Article
MeSH Terms:
CASP8 and FADD-Like Apoptosis Regulating Protein*/genetics
CASP8 and FADD-Like Apoptosis Regulating Protein*/metabolism
Death Effector Domain*
Apoptosis ; Caspase 8/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Follow-Up Studies
Czasopismo naukowe
Tytuł:
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro .
Autorzy:
Yang Y; School of Pharmacy, Guilin Medical University, Guilin, PR China.; School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, PR China.
Ren ZZ; School of Pharmacy, Guilin Medical University, Guilin, PR China.; School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, PR China.
Wei WJ; School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, PR China.; Department of Laboratory Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, PR China.
He ZL; School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, PR China.; College of Light Industry and Food Engineering, Guangxi University, Nanning, PR China.
Deng YL; School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, PR China.
Wang Z; College of Light Industry and Food Engineering, Guangxi University, Nanning, PR China.
Fan YC; Medical College, Guangxi University, Nanning, PR China.
Zhou J; Medical College, Guangxi University, Nanning, PR China.
Jiang LH; School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, PR China.; College of Light Industry and Food Engineering, Guangxi University, Nanning, PR China.; Medical College, Guangxi University, Nanning, PR China.; Key Laboratory of Tumor Immunology and Pathology (Army Medical University), Ministry of Education, Chongqing, PR China.
Pokaż więcej
Źródło:
Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 1566-1577.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Nasopharyngeal Neoplasms*/drug therapy
Nasopharyngeal Neoplasms*/metabolism
Nasopharyngeal Neoplasms*/pathology
Apoptosis Regulatory Proteins ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Coumarins ; Humans ; Nasopharyngeal Carcinoma/drug therapy ; Nasopharyngeal Carcinoma/pathology ; RNA/pharmacology ; RNA/therapeutic use ; Reactive Oxygen Species
Czasopismo naukowe
Tytuł:
Alternative splicing of Apoptosis Stimulating Protein of TP53-2 (ASPP2) results in an oncogenic isoform promoting migration and therapy resistance in soft tissue sarcoma (STS).
Autorzy:
Tsintari V; Department of Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tübingen (UKT), Tübingen, Germany.
Walter B; Department of Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tübingen (UKT), Tübingen, Germany.
Fend F; Institute of Pathology, University Hospital Tübingen, Tübingen, Germany.
Overkamp M; Institute of Pathology, University Hospital Tübingen, Tübingen, Germany.
Rothermundt C; Department of Medical Oncology and Hematology, Cantonal Hospital St. Gallen (KSSG), St. Gallen, Switzerland.
Lopez CD; Department of Hematology and Medical Oncology, Oregon Health and Science University (OHSU), Portland, OR, USA.
Schittenhelm MM; Department of Medical Oncology and Hematology, Cantonal Hospital St. Gallen (KSSG), St. Gallen, Switzerland.
Kampa-Schittenhelm KM; Department of Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tübingen (UKT), Tübingen, Germany. .; Laboratory of Translational Experimental Hematology and Oncology, Medical Research Center and Department of Medical Oncology and Hematology, Cantonal Hospital, Rorschacherstr. 95, St. Gallen, 9007, Switzerland, St.Gallen. .; St. Gallen, Switzerland. .
Pokaż więcej
Źródło:
BMC cancer [BMC Cancer] 2022 Jul 02; Vol. 22 (1), pp. 725. Date of Electronic Publication: 2022 Jul 02.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis Regulatory Proteins*/genetics
Apoptosis Regulatory Proteins*/metabolism
Carcinogenesis*/genetics
Carcinogenesis*/metabolism
Rhabdomyosarcoma*/genetics
Rhabdomyosarcoma*/metabolism
Sarcoma*/genetics
Sarcoma*/metabolism
Soft Tissue Neoplasms*/genetics
Soft Tissue Neoplasms*/metabolism
Alternative Splicing ; Apoptosis/genetics ; Drug Resistance, Neoplasm/genetics ; Drug Resistance, Neoplasm/physiology ; Humans ; Protein Isoforms/metabolism ; RNA, Messenger/metabolism ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł:
Biosynthetic cell membrane vesicles to enhance TRAIL-mediated apoptosis driven by photo-triggered oxidative stress.
Autorzy:
Li F; School of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, P.R. China.; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China. .
Wang X; School of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, P.R. China.; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China. .
Wu M; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China. .; Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China.
Guan J; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China. .; College of Biological Science and Engineering, Fuzhou University, Fuzhou 350116, P. R. China.
Liang Y; School of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, P.R. China.; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China. .
Liu X; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China. .; Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China.
Lin X; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China. .; Mengchao Med-X Center, Fuzhou University, Fuzhou 350116, P. R. China.
Liu J; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China. .; Fujian Cancer Hospital & Fujian Medical University Cancer Hospital, Fuzhou 350014, P. R. China.
Pokaż więcej
Źródło:
Biomaterials science [Biomater Sci] 2022 Jun 28; Vol. 10 (13), pp. 3547-3558. Date of Electronic Publication: 2022 Jun 28.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, TNF-Related Apoptosis-Inducing Ligand*
TNF-Related Apoptosis-Inducing Ligand*/metabolism
TNF-Related Apoptosis-Inducing Ligand*/pharmacology
Apoptosis ; Carrier Proteins/metabolism ; Cell Membrane/metabolism ; Cytochromes c/metabolism ; Oxidative Stress ; Reactive Oxygen Species/metabolism
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies

Prześlij opinię

Twoje opinie są dla nas bardzo ważne i mogą być niezwykle pomocne w pokazaniu nam, gdzie możemy dokonać ulepszeń. Bylibyśmy bardzo wdzięczni za poświęcenie kilku chwil na wypełnienie krótkiego formularza.

Formularz