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Wyszukujesz frazę ""ASTROCYTES"" wg kryterium: Temat


Tytuł:
Extracellular ATP release predominantly mediates Ca2+ communication locally in highly organised, stellate-Like patterned networks of adult human astrocytes.
Autorzy:
Li S; Department of Engineering Science, The University of Auckland, Auckland, New Zealand.; The MacDiarmid Institute for Advanced Materials and Nanotechnology, Auckland, New Zealand.
Graham ES; Department of Molecular Medicine and Pathology & Centre for Brain Research, The University of Auckland, Auckland, New Zealand.
Unsworth CP; Department of Engineering Science, The University of Auckland, Auckland, New Zealand.; The MacDiarmid Institute for Advanced Materials and Nanotechnology, Auckland, New Zealand.
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Źródło:
PloS one [PLoS One] 2023 Oct 03; Vol. 18 (10), pp. e0289350. Date of Electronic Publication: 2023 Oct 03 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Astrocytes*/metabolism
Calcium*/metabolism
Humans ; Adult ; Calcium Signaling ; Gap Junctions/metabolism ; Cell Communication ; Communication ; Adenosine Triphosphate/metabolism ; Cells, Cultured
Czasopismo naukowe
Tytuł:
Using the metabolite alterations monitoring the AEG-1 expression level and cell biological behaviour of U251 cell in vitro.
Autorzy:
Sheng Y; Department of Radiology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, China.
Yin D; Department of Radiology, The Second Hospital of Tianjin Medical University, Tianjin, China.
Zeng Q; Department of Radiology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, China.
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Źródło:
PloS one [PLoS One] 2023 Sep 01; Vol. 18 (9), pp. e0291092. Date of Electronic Publication: 2023 Sep 01 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes*
Glioma*
Humans ; Choline ; Gene Expression ; Lactic Acid ; Oncogenes
Czasopismo naukowe
Tytuł:
Regulation of the phagocytic activity of astrocytes by neuroimmune mediators endogenous to the central nervous system.
Autorzy:
Yang SS; Department of Biology, University of British Columbia Okanagan Campus, University Way, Kelowna, British Columbia, Canada.
Simtchouk S; Department of Biology, University of British Columbia Okanagan Campus, University Way, Kelowna, British Columbia, Canada.
Gibon J; Department of Biology, University of British Columbia Okanagan Campus, University Way, Kelowna, British Columbia, Canada.
Klegeris A; Department of Biology, University of British Columbia Okanagan Campus, University Way, Kelowna, British Columbia, Canada.
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Źródło:
PloS one [PLoS One] 2023 Jul 27; Vol. 18 (7), pp. e0289169. Date of Electronic Publication: 2023 Jul 27 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes*
Lipopolysaccharides*/pharmacology
Mice ; Animals ; Humans ; Cells, Cultured ; Microglia/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Phagocytes/metabolism ; Brain/metabolism ; Inflammation Mediators/pharmacology
Czasopismo naukowe
Tytuł:
The neuroprotective effect of human primary astrocytes in multiple sclerosis: In vitro model.
Autorzy:
Imraish A; Department of Biological Sciences, School of Science, The University of Jordan, Amman, Jordan.
Abu Thiab T; Department of Biological Sciences, School of Science, The University of Jordan, Amman, Jordan.
Alsalem M; Department of Anatomy and Histology, School of Medicine, The University of Jordan, Amman, Jordan.
Dahbour S; Department of Neurology, Jordan University Hospital, The University of Jordan, Amman, Jordan.
Khleif H; Department of Biological Sciences, School of Science, The University of Jordan, Amman, Jordan.
Abu-Irmaileh B; Hamdi Mango Centre for Scientific Research, The University of Jordan, Amman, Jordan.
Qasem R; Department of Biological Sciences, School of Science, The University of Jordan, Amman, Jordan.
El-Salem K; Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
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Źródło:
PloS one [PLoS One] 2024 Apr 02; Vol. 19 (4), pp. e0300203. Date of Electronic Publication: 2024 Apr 02 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/metabolism
Multiple Sclerosis*/pathology
Humans ; Astrocytes/metabolism ; Inflammation/pathology ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice.
Autorzy:
Iyer AK; Department of Neuroscience, Washington University School of Medicine, St. Louis, Missouri, United States of America.; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Schoch KM; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Verbeck A; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Galasso G; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Chen H; Department of Neuroscience, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Smith S; Department of Neuroscience, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Oldenborg A; Department of Neuroscience, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Miller TM; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Karch CM; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Bonni A; Neuroscience and Rare Diseases, Roche Pharma Research and Early Development (pRED), Roche Innovation Centre Basel, Basel, Switzerland.
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Źródło:
PloS one [PLoS One] 2023 Nov 28; Vol. 18 (11), pp. e0294731. Date of Electronic Publication: 2023 Nov 28 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/pathology
Animals ; Mice ; Astrocytes/metabolism ; Disease Models, Animal ; Mice, Transgenic ; Motor Neurons/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism ; Spinal Cord/metabolism ; Superoxide Dismutase/metabolism ; Superoxide Dismutase-1/genetics ; Superoxide Dismutase-1/metabolism
Czasopismo naukowe
Tytuł:
Astrocytes and pericytes attenuate severely injured patient plasma mediated expression of tight junction proteins in endothelial cells.
Autorzy:
Stafford P; Division of GITES, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Mitra S; Division of GITES, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Debot M; Division of GITES, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Lutz P; Division of GITES, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Stem A; Division of GITES, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Hadley J; Division of GITES, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Hom P; Division of GITES, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Schaid TR; Division of GITES, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Cohen MJ; Division of GITES, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
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Źródło:
PloS one [PLoS One] 2022 Jul 05; Vol. 17 (7), pp. e0270817. Date of Electronic Publication: 2022 Jul 05 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Astrocytes*/metabolism
Pericytes*/metabolism
Culture Media, Conditioned/metabolism ; Culture Media, Conditioned/pharmacology ; Endothelial Cells/metabolism ; Humans ; RNA, Messenger/metabolism ; Tight Junction Proteins/genetics ; Tight Junction Proteins/metabolism
Czasopismo naukowe
Tytuł:
Association between Change in the peripheral biomarkers of inflammation, astrocyte activation, and neuroprotection at one week of critical illness and hospital mortality in patients with delirium: A prospective cohort study.
Autorzy:
Khan SH; Department of Medicine, Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Indiana University School of Medicine, Indianapolis, IN, United States of America.; Regenstrief Institute, IU Center of Aging Research, Indianapolis, IN, United States of America.
Perkins AJ; Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN, United States of America.
Eltarras AM; Department of Internal Medicine, Indiana University School of Medicine, Indianapolis, IN, United States of America.
Chi R; Department of Medicine, Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Indiana University School of Medicine, Indianapolis, IN, United States of America.
Athar AA; Regenstrief Institute, IU Center of Aging Research, Indianapolis, IN, United States of America.
Wang S; Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, United States of America.
Campbell NL; Department of Pharmacy, Purdue University, Lafayette, IN, United States of America.
Gao S; Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN, United States of America.
Boustani MA; Regenstrief Institute, IU Center of Aging Research, Indianapolis, IN, United States of America.
Khan BA; Department of Medicine, Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Indiana University School of Medicine, Indianapolis, IN, United States of America.; Regenstrief Institute, IU Center of Aging Research, Indianapolis, IN, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Sep 01; Vol. 18 (9), pp. e0290298. Date of Electronic Publication: 2023 Sep 01 (Print Publication: 2023).
Typ publikacji:
Observational Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Critical Illness*
Delirium*
Adult ; Humans ; Hospital Mortality ; Neuroprotection ; Astrocytes ; Interleukin-10 ; Interleukin-6 ; Prospective Studies ; Biomarkers ; Inflammation
Czasopismo naukowe
Tytuł:
Adjusting the neuron to astrocyte ratio with cytostatics in hippocampal cell cultures from postnatal rats: A comparison of cytarabino furanoside (AraC) and 5-fluoro-2'-deoxyuridine (FUdR).
Autorzy:
Lesslich HM; Department of Biochemistry II, Ruhr-Universität Bochum, Bochum, Germany.
Klapal L; Department of Biochemistry II, Ruhr-Universität Bochum, Bochum, Germany.
Wilke J; Department of Biochemistry II, Ruhr-Universität Bochum, Bochum, Germany.
Haak A; Nanoscopy Group, RUBION, Ruhr-Universität Bochum, Bochum, Germany.
Dietzel ID; Department of Biochemistry II, Ruhr-Universität Bochum, Bochum, Germany.
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Źródło:
PloS one [PLoS One] 2022 Mar 09; Vol. 17 (3), pp. e0265084. Date of Electronic Publication: 2022 Mar 09 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Astrocytes*/metabolism
Cytostatic Agents*/pharmacology
Animals ; Cell Culture Techniques ; Cells, Cultured ; Deoxyuridine/analogs & derivatives ; Floxuridine/pharmacology ; Hippocampus ; Neurons/metabolism ; Rats
Czasopismo naukowe
Tytuł:
Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia.
Autorzy:
Wu J; Department of Ophthalmology and Visual Sciences, Kentucky Lions Eye Center, University of Louisville, School of Medicine, Louisville, Kentucky, United States of America.; Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Chen N; Department of Ophthalmology and Visual Sciences, Kentucky Lions Eye Center, University of Louisville, School of Medicine, Louisville, Kentucky, United States of America.; Tianjin Key Laboratory of Retinal Functions and Diseases, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, P.R. China.
Liu Y; Department of Medicine-Oncology, University of Louisville, School of Medicine, Louisville, Kentucky, United States of America.
Godlewski G; Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism of the National Institutes of Health, Bethesda, Maryland, United States of America.
Kaplan HJ; Department of Ophthalmology and Visual Sciences, Kentucky Lions Eye Center, University of Louisville, School of Medicine, Louisville, Kentucky, United States of America.
Shrader SH; Department of Pharmacology and Toxicology, University of Louisville, School of Medicine, Louisville, Kentucky, United States of America.
Song ZH; Department of Pharmacology and Toxicology, University of Louisville, School of Medicine, Louisville, Kentucky, United States of America.
Shao H; Department of Ophthalmology and Visual Sciences, Kentucky Lions Eye Center, University of Louisville, School of Medicine, Louisville, Kentucky, United States of America.
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Źródło:
PloS one [PLoS One] 2021 May 13; Vol. 16 (5), pp. e0251677. Date of Electronic Publication: 2021 May 13 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Astrocytes/*drug effects
Cannabidiol/*pharmacology
Microglia/*drug effects
Receptors, G-Protein-Coupled/*metabolism
Animals ; Anti-Inflammatory Agents/therapeutic use ; Astrocytes/immunology ; Astrocytes/metabolism ; Cannabidiol/therapeutic use ; Cells, Cultured ; Cytokines/metabolism ; Disease Models, Animal ; Humans ; Inflammation/drug therapy ; Inflammation/immunology ; Inflammation Mediators/metabolism ; Lipopolysaccharides/immunology ; Mice ; Microglia/immunology ; Microglia/metabolism ; Primary Cell Culture ; Signal Transduction/drug effects ; Signal Transduction/immunology
Czasopismo naukowe
Tytuł:
Psychostimulants and opioids differentially influence the epigenetic modification of histone acetyltransferase and histone deacetylase in astrocytes.
Autorzy:
Doke M; Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M University, Kingsville, Texas, United States of America.
Pendyala G; Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, United States of America.
Samikkannu T; Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M University, Kingsville, Texas, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Jun 11; Vol. 16 (6), pp. e0252895. Date of Electronic Publication: 2021 Jun 11 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Astrocytes/*drug effects
Central Nervous System Stimulants/*pharmacology
Cocaine/*pharmacology
Histone Acetyltransferases/*genetics
Histone Deacetylases/*genetics
Methamphetamine/*pharmacology
Morphine/*pharmacology
Acetylation/drug effects ; Astrocytes/enzymology ; Epigenesis, Genetic/drug effects ; Gene Expression Regulation, Enzymologic/drug effects ; Histone Acetyltransferases/metabolism ; Histone Deacetylases/metabolism ; Humans ; Piracetam/pharmacology ; Primary Cell Culture ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł:
Mesencephalic astrocyte-derived neurotrophic factor is secreted from interferon-γ-activated tumor cells through ER calcium depletion.
Autorzy:
Peled M; Institute of Pulmonary Medicine, Sheba Medical Center, Tel Hashomer, Israel.; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Bar-Lev TH; Institute of Pulmonary Medicine, Sheba Medical Center, Tel Hashomer, Israel.
Talalai E; Institute of Pulmonary Medicine, Sheba Medical Center, Tel Hashomer, Israel.; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Aspitz HZ; Institute of Pulmonary Medicine, Sheba Medical Center, Tel Hashomer, Israel.; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Daniel-Meshulam I; Institute of Pulmonary Medicine, Sheba Medical Center, Tel Hashomer, Israel.
Bar J; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.; Thoracic Oncology Unit, Institute of Oncology, Sheba Medical Center, Tel Hashomer, Israel.
Kamer I; Thoracic Oncology Unit, Institute of Oncology, Sheba Medical Center, Tel Hashomer, Israel.
Ofek E; Pathology Department, Tel HaShomer Hospital, Tel Hashomer, Israel.
Mor A; Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY, United States of America.
Onn A; Institute of Pulmonary Medicine, Sheba Medical Center, Tel Hashomer, Israel.
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Źródło:
PloS one [PLoS One] 2021 Apr 23; Vol. 16 (4), pp. e0250178. Date of Electronic Publication: 2021 Apr 23 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Astrocytes/*metabolism
B7-H1 Antigen/*metabolism
Calcium/*metabolism
Endoplasmic Reticulum/*metabolism
Interferon-gamma/*pharmacology
Nerve Growth Factors/*metabolism
Astrocytes/drug effects ; Cell Line, Tumor ; Endoplasmic Reticulum/drug effects ; Hep G2 Cells ; Humans
Czasopismo naukowe
Tytuł:
Cryopreservation of human cerebral microvascular endothelial cells and astrocytes in suspension and monolayers.
Autorzy:
Marquez-Curtis LA; Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, Canada.; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.
Bokenfohr R; Department of Medicine, University of Alberta, Edmonton, AB, Canada.
McGann LE; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.
Elliott JAW; Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, Canada.; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.
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Źródło:
PloS one [PLoS One] 2021 Apr 14; Vol. 16 (4), pp. e0249814. Date of Electronic Publication: 2021 Apr 14 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Astrocytes/*cytology
Blood-Brain Barrier/*cytology
Cryopreservation/*methods
Astrocytes/metabolism ; Cells, Cultured ; Claudin-1/genetics ; Claudin-1/metabolism ; Dimethyl Sulfoxide/chemistry ; Endothelial Cells/cytology ; Endothelial Cells/metabolism ; Humans ; Microvessels/cytology ; Nitrogen/chemistry ; Serum Albumin, Bovine/chemistry ; Starch/analogs & derivatives ; Zonula Occludens-1 Protein/genetics ; Zonula Occludens-1 Protein/metabolism
Czasopismo naukowe
Tytuł:
Astrocytes derived from neural progenitor cells are susceptible to Zika virus infection.
Autorzy:
Rubio-Hernández EI; Laboratorio de Células Neurales Troncales Humanas, Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología-Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.
Comas-García M; Sección de Microscopia de Alta Resolución, Centro de Investigación en Ciencias de la Salud y Biomedicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.; Facultad de Ciencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.
Coronado-Ipiña MA; Sección de Microscopia de Alta Resolución, Centro de Investigación en Ciencias de la Salud y Biomedicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.
Colunga-Saucedo M; Sección de Genómica Médica, Centro de Investigación en Ciencias de la Salud y Biomedicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.
González Sánchez HM; Cátedra CONACYT- Centro de Investigación sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Cuernavaca, México.
Castillo CG; Laboratorio de Células Neurales Troncales Humanas, Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología-Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.
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Źródło:
PloS one [PLoS One] 2023 Mar 29; Vol. 18 (3), pp. e0283429. Date of Electronic Publication: 2023 Mar 29 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Zika Virus Infection*
Zika Virus*
Microcephaly*
Neural Stem Cells*
Pregnancy ; Infant ; Adult ; Female ; Humans ; Astrocytes
Czasopismo naukowe
Tytuł:
Astrocyte responses to experimental glaucoma in mouse optic nerve head.
Autorzy:
Quillen S; Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Schaub J; Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Quigley H; Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Pease M; Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Korneva A; Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Kimball E; Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Aug 21; Vol. 15 (8), pp. e0238104. Date of Electronic Publication: 2020 Aug 21 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Astrocytes/*physiology
Glaucoma/*pathology
Optic Nerve/*physiology
Animals ; Apoptosis ; Astrocytes/cytology ; Astrocytes/pathology ; Cell Proliferation ; Disease Models, Animal ; Glial Fibrillary Acidic Protein/metabolism ; Intraocular Pressure ; Mice ; Mice, Inbred C57BL ; Microscopy, Confocal ; Microscopy, Electron, Transmission ; Optic Nerve/cytology ; Optic Nerve/pathology
Czasopismo naukowe
Tytuł:
The loss of microglia activities facilitates glaucoma progression in association with CYP1B1 gene mutation (p.Gly61Glu).
Autorzy:
Alghamdi A; Biochemistry Department, King Saud University (KSU), Riyadh, Saudi Arabia.
Aldossary W; Biochemistry Department, King Saud University (KSU), Riyadh, Saudi Arabia.
Albahkali S; Stem Cells and Regenerative Medicine, King Abdullah International Medical Research Center (KAIMRC), Riyadh, Saudi Arabia.
Alotaibi B; Stem Cells and Regenerative Medicine, King Abdullah International Medical Research Center (KAIMRC), Riyadh, Saudi Arabia.
Alrfaei BM; Stem Cells and Regenerative Medicine, King Abdullah International Medical Research Center (KAIMRC), Riyadh, Saudi Arabia.; King Saud Bin Abdulaziz University for Health Sciences (KSAU-HS), Riyadh, Saudi Arabia.
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Źródło:
PloS one [PLoS One] 2020 Nov 10; Vol. 15 (11), pp. e0241902. Date of Electronic Publication: 2020 Nov 10 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Point Mutation*
Astrocytes/*cytology
Cytochrome P-450 CYP1B1/*genetics
Glaucoma/*congenital
Mesenchymal Stem Cells/*cytology
Microglia/*cytology
Amino Acid Substitution ; Animals ; Apoptosis ; Astrocytes/metabolism ; CRISPR-Cas Systems ; Cell Proliferation ; Cells, Cultured ; Cytokines/metabolism ; Glaucoma/genetics ; Humans ; Male ; Mesenchymal Stem Cells/metabolism ; Microglia/metabolism ; Models, Animal ; NADP/metabolism ; Rats
Czasopismo naukowe
Tytuł:
Isolation and transcriptional characterization of mouse perivascular astrocytes.
Autorzy:
Yosef N; Department of Neurosurgery, University of Texas M.D. Anderson Cancer Center, Houston, TX, United States of America.
Xi Y; Department of Bioinformatics and Computational Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX, United States of America.
McCarty JH; Department of Neurosurgery, University of Texas M.D. Anderson Cancer Center, Houston, TX, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Oct 08; Vol. 15 (10), pp. e0240035. Date of Electronic Publication: 2020 Oct 08 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Astrocytes/*metabolism
Blood Vessels/*metabolism
Animals ; Astrocytes/cytology ; Blood Vessels/cytology ; Blood-Brain Barrier/metabolism ; Brain/cytology ; Brain/pathology ; Cell Communication/genetics ; Cells, Cultured ; Cluster Analysis ; Endothelial Cells/cytology ; Endothelial Cells/metabolism ; Extracellular Matrix Proteins/metabolism ; Mice ; Sequence Analysis, RNA ; Single-Cell Analysis ; Transcriptome
Czasopismo naukowe
Tytuł:
Repetitive transcranial magnetic stimulation activates glial cells and inhibits neurogenesis after pneumococcal meningitis.
Autorzy:
Muri L; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, Bern, Switzerland.
Oberhänsli S; Interfaculty Bioinformatics Unit and SIB Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland.
Buri M; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, Bern, Switzerland.
Le ND; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, Bern, Switzerland.
Grandgirard D; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
Bruggmann R; Interfaculty Bioinformatics Unit and SIB Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland.
Müri RM; Department of Neurology, University of Bern, Bern, Switzerland.
Leib SL; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
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Źródło:
PloS one [PLoS One] 2020 Sep 11; Vol. 15 (9), pp. e0232863. Date of Electronic Publication: 2020 Sep 11 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neurogenesis*
Astrocytes/*cytology
Cerebellar Cortex/*cytology
Hippocampus/*cytology
Meningitis, Pneumococcal/*therapy
Microglia/*cytology
Transcranial Magnetic Stimulation/*adverse effects
Animals ; Astrocytes/pathology ; Cerebellar Cortex/pathology ; Cytokines/metabolism ; Hippocampus/pathology ; Male ; Microglia/pathology ; Rats ; Rats, Wistar ; Stem Cell Niche
Czasopismo naukowe
Tytuł:
Three-dimensional brain-on-chip model using human iPSC-derived GABAergic neurons and astrocytes: Butyrylcholinesterase post-treatment for acute malathion exposure.
Autorzy:
Liu L; FIT BEST Laboratory, Department of Chemical, Biological, and Bio Engineering, North Carolina Agricultural and Technical State University, Greensboro, North Carolina, United States of America.
Koo Y; FIT BEST Laboratory, Department of Chemical, Biological, and Bio Engineering, North Carolina Agricultural and Technical State University, Greensboro, North Carolina, United States of America.
Russell T; FIT BEST Laboratory, Department of Chemical, Biological, and Bio Engineering, North Carolina Agricultural and Technical State University, Greensboro, North Carolina, United States of America.
Gay E; Center for Drug Discovery, RTI International, Research Triangle Park, Durham, North Carolina, United States of America.
Li Y; Chemical Engineering, Florida A&M University-Florida State University, Tallahassee, Florida, United States of America.
Yun Y; FIT BEST Laboratory, Department of Chemical, Biological, and Bio Engineering, North Carolina Agricultural and Technical State University, Greensboro, North Carolina, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Mar 12; Vol. 15 (3), pp. e0230335. Date of Electronic Publication: 2020 Mar 12 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Astrocytes/*drug effects
Brain/*drug effects
Butyrylcholinesterase/*pharmacology
Cholinesterase Inhibitors/*toxicity
GABAergic Neurons/*drug effects
Induced Pluripotent Stem Cells/*cytology
Malathion/*antagonists & inhibitors
Astrocytes/cytology ; Astrocytes/metabolism ; Brain/cytology ; Cells, Cultured ; GABAergic Neurons/cytology ; GABAergic Neurons/metabolism ; Humans ; Malathion/toxicity
Czasopismo naukowe
Tytuł:
Glioma-derived exosomes drive the differentiation of neural stem cells to astrocytes.
Autorzy:
Sharma KD; Department of Biological Sciences and Arkansas Biosciences Institute, Arkansas State University, Jonesboro, Arkansas, United States of America.
Schaal D; Department of Biology, Ouachita Baptist University, Arkadelphia, Arkansas, United States of America.
Kore RA; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Hamzah RN; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Pandanaboina SC; Department of Biological Sciences and Arkansas Biosciences Institute, Arkansas State University, Jonesboro, Arkansas, United States of America.
Hayar A; Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Griffin RJ; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Srivatsan M; Department of Biological Sciences and Arkansas Biosciences Institute, Arkansas State University, Jonesboro, Arkansas, United States of America.
Reyna NS; Department of Biology, Ouachita Baptist University, Arkadelphia, Arkansas, United States of America.
Xie JY; Department of Basic Sciences, New York Institute of Technology College of Osteopathic Medicine at Arkansas State University, Jonesboro, Arkansas, United States of America.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2020 Jul 10; Vol. 15 (7), pp. e0234614. Date of Electronic Publication: 2020 Jul 10 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Astrocytes/*metabolism
Cell Differentiation/*physiology
Exosomes/*physiology
Neural Stem Cells/*metabolism
Animals ; Astrocytes/physiology ; Cell Proliferation ; Cells, Cultured ; Coculture Techniques ; Elastin/metabolism ; Exosomes/metabolism ; Gene Expression Regulation/genetics ; Glioma/metabolism ; Humans ; Interleukin-6/metabolism ; Metallothionein 3 ; Nerve Tissue Proteins/metabolism ; Neural Stem Cells/physiology ; Neurons/metabolism ; Primary Cell Culture ; Rats ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe
Tytuł:
Evidence-based beta blocker use associated with lower heart failure readmission and mortality, but not all-cause readmission, among Medicare beneficiaries hospitalized for heart failure with reduced ejection fraction.
Autorzy:
Loop MS; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Van Dyke MK; Center for Observational Research, Amgen Inc., Thousand Oaks, California, United States of America.
Chen L; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Brown TM; Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Durant RW; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Safford MM; Division of General Internal Medicine, Weill Cornell Medical College, Birmingham, Alabama, United States of America.
Levitan EB; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2020 Jul 09; Vol. 15 (7), pp. e0233161. Date of Electronic Publication: 2020 Jul 09 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Astrocytes/*virology
Cysteine-Rich Protein 61/*metabolism
Zika Virus/*physiology
Zika Virus Infection/*virology
Animals ; Astrocytes/metabolism ; Astrocytoma/metabolism ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Cell Line ; Cyclic AMP Response Element-Binding Protein/metabolism ; Cysteine-Rich Protein 61/genetics ; Humans ; Mice ; Mice, Inbred C57BL ; Phosphorylation ; Serine Endopeptidases/metabolism ; Up-Regulation ; Viral Nonstructural Proteins/metabolism ; Viral Proteins/metabolism ; Virus Replication ; Zika Virus Infection/metabolism
Czasopismo naukowe

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