Temat: "ATP Binding Cassette Transporter, Subfamily G, Member 2" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The inhibition of ABCB1/MDR1 or ABCG2/BCRP enables doxorubicin to eliminate liver cancer stem cells.
Autorzy:: Yin W; School of Medicine, IMPACT, Institute for Innovation in Physical and Mental Health and Clinical Translation, Deakin University, Geelong, VIC, 3216, Australia.
Xiang D; State Key Laboratory of Oncogenes and Related Genes, Shanghai, 200127, China.; Department of Biliary-Pancreatic Surgery, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, 200092, China.
Wang T; Centre for Comparative Genomics, Murdoch University, Perth, WA, 6150, Australia.; School of Nursing, Zhengzhou University, Zhengzhou, 450001, China.
Zhang Y; School of Medicine, IMPACT, Institute for Innovation in Physical and Mental Health and Clinical Translation, Deakin University, Geelong, VIC, 3216, Australia.
Pham CV; School of Medicine, IMPACT, Institute for Innovation in Physical and Mental Health and Clinical Translation, Deakin University, Geelong, VIC, 3216, Australia.
Zhou S; Department of Chemical Engineering & Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, 361021, China.
Jiang G; Department of General Surgery, Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Suzhou, 215004, China.
Hou Y; Laboratory of Tumor Molecular and Cellular Biology, College of Life Sciences, Shaanxi Normal University, 620 West Chang'an Avenue, Xi'an, 710119, Shaanxi, China.
Zhu Y; CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, China.
Han Y; Shanghai OneTar Biomedicine, Shanghai, 201203, China.
Qiao L; Storr Liver Centre, Westmead Institute for Medical Research, University of Sydney and Westmead Hospital, Westmead, NSW, 2145, Australia.
Tran PH; School of Medicine, IMPACT, Institute for Innovation in Physical and Mental Health and Clinical Translation, Deakin University, Geelong, VIC, 3216, Australia. .
Duan W; School of Medicine, IMPACT, Institute for Innovation in Physical and Mental Health and Clinical Translation, Deakin University, Geelong, VIC, 3216, Australia. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 May 24; Vol. 11 (1), pp. 10791. Date of Electronic Publication: 2021 May 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Drug Resistance, Neoplasm*/drug effects
ATP Binding Cassette Transporter, Subfamily G, Member 2/*metabolism
Carcinoma, Hepatocellular/*metabolism
Doxorubicin/*pharmacology
Liver Neoplasms/*metabolism
Neoplasm Proteins/*metabolism
Neoplastic Stem Cells/*metabolism
ATP Binding Cassette Transporter, Subfamily B/antagonists & inhibitors ; ATP Binding Cassette Transporter, Subfamily B/metabolism ; ATP Binding Cassette Transporter, Subfamily G, Member 2/antagonists & inhibitors ; Carcinoma, Hepatocellular/drug therapy ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cyclosporins/pharmacology ; Diketopiperazines/pharmacology ; Drug Synergism ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Silencing ; Heterocyclic Compounds, 4 or More Rings/pharmacology ; Humans ; Liver Neoplasms/drug therapy ; Neoplasm Proteins/antagonists & inhibitors ; Neoplastic Stem Cells/drug effects ; Up-Regulation/drug effects

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Skocz do pozycji: 2.

Tytuł:: ABCB1 expression is increased in human first trimester placenta from pregnant women classified as overweight or obese.
Autorzy:: Justesen S; Department of Biomedicine, Aarhus University, Høegh-Guldbergs Gade 10, 8000, Aarhus C, Denmark.
Bilde K; Department of Biomedicine, Aarhus University, Høegh-Guldbergs Gade 10, 8000, Aarhus C, Denmark.
Olesen RH; Department of Biomedicine, Aarhus University, Høegh-Guldbergs Gade 10, 8000, Aarhus C, Denmark.; Department of Obstetrics and Gynecology, Randers Regional Hospital, 8930, Randers, Denmark.
Pedersen LH; Department of Biomedicine, Aarhus University, Høegh-Guldbergs Gade 10, 8000, Aarhus C, Denmark.; Department of Clinical Medicine, Aarhus University, 8200, Aarhus N, Denmark.; Department of Obstetrics and Gynecology, Aarhus University Hospital, 8200, Aarhus N, Denmark.
Ernst E; Department of Biomedicine, Aarhus University, Høegh-Guldbergs Gade 10, 8000, Aarhus C, Denmark.; Department of Obstetrics and Gynecology, Horsens Regional Hospital, 8700, Horsens, Denmark.
Larsen A; Department of Biomedicine, Aarhus University, Høegh-Guldbergs Gade 10, 8000, Aarhus C, Denmark. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Mar 30; Vol. 13 (1), pp. 5175. Date of Electronic Publication: 2023 Mar 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Placenta*/metabolism
Premature Birth*/metabolism
Animals ; Female ; Pregnancy ; Humans ; Male ; Infant, Newborn ; Infant ; ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Pregnancy Trimester, First ; Overweight/metabolism ; Pregnant Women ; Neoplasm Proteins/genetics ; ATP Binding Cassette Transporter, Subfamily B/genetics ; ATP Binding Cassette Transporter, Subfamily B/metabolism ; Obesity/metabolism ; ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics ; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; Carrier Proteins/metabolism ; RNA, Messenger/metabolism

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Skocz do pozycji: 3.

Tytuł:: Hypouricemic agents reduce indoxyl sulfate excretion by inhibiting the renal transporters OAT1/3 and ABCG2.
Autorzy:: Taniguchi T; Research Laboratories 2, Fuji Yakuhin Co., Ltd., 636-1, Iida-Shinden, Nishi-ku, Saitama, Japan. .
Omura K; Research Laboratories 2, Fuji Yakuhin Co., Ltd., 636-1, Iida-Shinden, Nishi-ku, Saitama, Japan.
Motoki K; Research Laboratories 2, Fuji Yakuhin Co., Ltd., 636-1, Iida-Shinden, Nishi-ku, Saitama, Japan.
Sakai M; Research Laboratories 2, Fuji Yakuhin Co., Ltd., 636-1, Iida-Shinden, Nishi-ku, Saitama, Japan.
Chikamatsu N; Research Laboratories 2, Fuji Yakuhin Co., Ltd., 636-1, Iida-Shinden, Nishi-ku, Saitama, Japan.
Ashizawa N; Research Laboratories 2, Fuji Yakuhin Co., Ltd., 636-1, Iida-Shinden, Nishi-ku, Saitama, Japan.
Takada T; Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Iwanaga T; Research Laboratories 2, Fuji Yakuhin Co., Ltd., 636-1, Iida-Shinden, Nishi-ku, Saitama, Japan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Mar 31; Vol. 11 (1), pp. 7232. Date of Electronic Publication: 2021 Mar 31.
Typ publikacji:: Journal Article
MeSH Terms:: Acute Kidney Injury*/blood
Acute Kidney Injury*/chemically induced
Acute Kidney Injury*/drug therapy
ATP Binding Cassette Transporter, Subfamily G, Member 2/*antagonists & inhibitors
Indican/*blood
Organic Anion Transport Protein 1/*antagonists & inhibitors
Organic Anion Transporters, Sodium-Independent/*antagonists & inhibitors
Uricosuric Agents/*pharmacology
ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Animals ; Male ; Organic Anion Transport Protein 1/metabolism ; Organic Anion Transporters, Sodium-Independent/metabolism ; Rats ; Rats, Wistar

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Skocz do pozycji: 4.

Tytuł:: Evaluation of ABCG2-mediated extra-renal urate excretion in hemodialysis patients.
Autorzy:: Ohashi Y; Department of Pathophysiology, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji-Shi, Tokyo, 192-0392, Japan.
Toyoda M; Division of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara-Shi, Kanagawa, 259-1193, Japan.
Saito N; Division of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara-Shi, Kanagawa, 259-1193, Japan.
Koizumi M; Division of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara-Shi, Kanagawa, 259-1193, Japan.
Kanai G; Division of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara-Shi, Kanagawa, 259-1193, Japan.
Komaba H; Division of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara-Shi, Kanagawa, 259-1193, Japan.
Kimura M; Division of Nephrology, Endocrinology and Metabolism, Tokai University Oiso Hospital, 21-1 Gakkyo, Oiso-Machi, Naka-Gun, Kanagawa, 259-0198, Japan.
Wada T; Division of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara-Shi, Kanagawa, 259-1193, Japan.
Takahashi H; Jinken Clinic, 15-1 Ogi-Cho, Ebina-Shi, Kanagawa, 243-0436, Japan.
Takahashi Y; Jinken Clinic, 15-1 Ogi-Cho, Ebina-Shi, Kanagawa, 243-0436, Japan.
Ishida N; Seichi Clinic, 5-19-8 Numame, Isehara-Shi, Kanagawa, 259-1126, Japan.
Kakuta T; Division of Nephrology, Endocrinology and Metabolism, Tokai University Hachioji Hospital, 1838 Ishikawa-Machi, Hachioji-Shi, Tokyo, 192-0032, Japan.
Fukagawa M; Division of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara-Shi, Kanagawa, 259-1193, Japan.
Ichida K; Department of Pathophysiology, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji-Shi, Tokyo, 192-0392, Japan. .; Division of Kidney and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, 3-19-18 Shinbashi, Minato-Ku, Tokyo, 105-8471, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Jan 13; Vol. 13 (1), pp. 93. Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:: Journal Article
MeSH Terms:: Gout*/genetics
Gout*/metabolism
Hyperuricemia*
Humans ; Uric Acid ; Kidney/metabolism ; Renal Dialysis ; ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism

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Skocz do pozycji: 5.

Tytuł:: Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma.
Autorzy:: Gampa G; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.
Kenchappa RS; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.
Mohammad AS; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.
Parrish KE; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.
Kim M; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.
Crish JF; Department of Cancer Biology, Cleveland Clinic, Cleveland, OH, USA.
Luu A; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.
West R; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.
Hinojosa AQ; Department of Neurologic Surgery, Mayo Clinic, Jacksonville, FL, USA.
Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA.
Rosenfeld SS; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA. .
Elmquist WF; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Apr 16; Vol. 10 (1), pp. 6524. Date of Electronic Publication: 2020 Apr 16.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: ATP Binding Cassette Transporter, Subfamily G, Member 2/*genetics
Benzamides/*pharmacology
Cell Proliferation/*drug effects
Kinesins/*antagonists & inhibitors
Neoplasm Proteins/*genetics
Quinazolines/*pharmacology
ATP Binding Cassette Transporter, Subfamily B/antagonists & inhibitors ; ATP Binding Cassette Transporter, Subfamily B/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 2/antagonists & inhibitors ; Acridines/chemistry ; Acridines/pharmacology ; Animals ; Blood-Brain Barrier/drug effects ; Brain ; Cell Line, Tumor ; Disease Models, Animal ; Glioblastoma/genetics ; Glioblastoma/pathology ; Humans ; Kinesins/genetics ; Mice ; Molecular Targeted Therapy ; Neoplasm Invasiveness/genetics ; Neoplasm Invasiveness/pathology ; Neoplasm Proteins/antagonists & inhibitors ; Tetrahydroisoquinolines/chemistry ; Tetrahydroisoquinolines/pharmacology ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 6.

Tytuł:: Biomarker LEPRE1 induces pelitinib-specific drug responsiveness by regulating ABCG2 expression and tumor transition states in human leukemia and lung cancer.
Autorzy:: Lee AR; Department of Advanced Toxicology, Korea Institute of Toxicology (KIT), Daejeon, 34114, Republic of Korea.; Bio Center, LegoChem Biosciences, Inc., Daejeon, 34002, Republic of Korea.
Lee S; Genome Data Integration Centre, Syntekabio Inc., Daejeon, 34025, Republic of Korea.; Department of Computer Science and Engineering, Seoul National University, Seoul, 08826, Republic of Korea.
Shin JY; Genome Data Integration Centre, Syntekabio Inc., Daejeon, 34025, Republic of Korea.
Kim JY; Department of Advanced Toxicology, Korea Institute of Toxicology (KIT), Daejeon, 34114, Republic of Korea.
Moon KS; Department of Advanced Toxicology, Korea Institute of Toxicology (KIT), Daejeon, 34114, Republic of Korea. .
Jung J; Genome Data Integration Centre, Syntekabio Inc., Daejeon, 34025, Republic of Korea. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Feb 21; Vol. 12 (1), pp. 2928. Date of Electronic Publication: 2022 Feb 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Biomarkers, Tumor*
ATP Binding Cassette Transporter, Subfamily G, Member 2/*genetics
ATP Binding Cassette Transporter, Subfamily G, Member 2/*metabolism
Aminoquinolines/*pharmacology
Aniline Compounds/*pharmacology
Antineoplastic Agents/*pharmacology
Epithelial-Mesenchymal Transition/*genetics
Gene Expression Regulation, Leukemic/*genetics
Gene Expression Regulation, Neoplastic/*genetics
Leukemia, Myeloid, Acute/*genetics
Leukemia, Myeloid, Acute/*pathology
Lung Neoplasms/*genetics
Lung Neoplasms/*pathology
Membrane Glycoproteins/*genetics
Membrane Glycoproteins/*physiology
Neoplasm Proteins/*genetics
Neoplasm Proteins/*metabolism
Prolyl Hydroxylases/*genetics
Prolyl Hydroxylases/*physiology
Proteoglycans/*genetics
Proteoglycans/*physiology
Cell Line, Tumor ; Drug Resistance, Neoplasm/genetics ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Lung Neoplasms/diagnosis

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Skocz do pozycji: 7.

Tytuł:: Mid-pregnancy poly(I:C) viral mimic disrupts placental ABC transporter expression and leads to long-term offspring motor and cognitive dysfunction.
Autorzy:: Monteiro VRS; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Andrade CBV; Departamento de Histologia e Embriologia, Instituto de Biologia Roberto Alcantara Gomes, Universidade Estadual Do Rio de Janeiro, Rio de Janeiro, Brasil.
Gomes HR; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Reginatto MW; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Império GE; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada.
Fontes KN; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Spiess DA; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Rangel-Junior WS; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Nascimento VMO; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Lima COS; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Sousa RPC; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Bloise FF; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Matthews SG; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada.; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Canada.; Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Toronto, Toronto, Canada.; Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Canada.
Bloise E; Departamento de Morfologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.
Pimentel-Coelho PM; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Ortiga-Carvalho TM; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jun 17; Vol. 12 (1), pp. 10262. Date of Electronic Publication: 2022 Jun 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: ATP-Binding Cassette Transporters*/metabolism
Cognitive Dysfunction*/metabolism
ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Animals ; Female ; Membrane Transport Proteins/metabolism ; Mice ; Mice, Inbred C57BL ; Neoplasm Proteins/metabolism ; Placenta/metabolism ; Poly I-C/pharmacology ; Pregnancy

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Skocz do pozycji: 8.

Tytuł:: Identification of ABCG2 as an Exporter of Uremic Toxin Indoxyl Sulfate in Mice and as a Crucial Factor Influencing CKD Progression.
Autorzy:: Takada T; Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo, Tokyo, Japan. .
Yamamoto T; Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Matsuo H; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
Tan JK; Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Ooyama K; Department of Renal Disease, Tsubasa Clinic, Tokyo, Japan.
Sakiyama M; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
Miyata H; Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Yamanashi Y; Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Toyoda Y; Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Higashino T; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
Nakayama A; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
Nakashima A; Division of Kidney and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan.
Shinomiya N; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
Ichida K; Department of Pathophysiology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
Ooyama H; Department of Internal Medicine, Ryogoku East Gate Clinic, Tokyo, Japan.
Fujimori S; Teikyo University Shinjuku Clinic, Tokyo, Japan.
Suzuki H; Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo, Tokyo, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2018 Jul 24; Vol. 8 (1), pp. 11147. Date of Electronic Publication: 2018 Jul 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: ATP Binding Cassette Transporter, Subfamily G, Member 2/*metabolism
Indican/*urine
Neoplasm Proteins/*metabolism
Renal Insufficiency, Chronic/*blood
Renal Insufficiency, Chronic/*urine
Toxins, Biological/*urine
ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics ; Adenine/adverse effects ; Adenosine Triphosphate/metabolism ; Analysis of Variance ; Animals ; Chromatography, Liquid ; Disease Models, Animal ; Disease Progression ; Gene Knockout Techniques ; HEK293 Cells ; Half-Life ; Humans ; Indican/blood ; Mice ; Mice, Knockout ; Renal Elimination ; Renal Insufficiency, Chronic/chemically induced ; Tandem Mass Spectrometry ; Transport Vesicles/metabolism

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Skocz do pozycji: 9.

Tytuł:: Association and interaction between dietary patterns and gene polymorphisms in Liangshan residents with hyperuricemia.
Autorzy:: Li T; School of Public Health, Southwest Medical University, Luzhou, Sichuan, China.; Western Theater Command Air Force Hospital, Chengdu, Sichuan, China.
Li S; Nursing Department, Yaan Vocational and Technical College, Yaan, Sichuan, China.
Tian T; School of Public Health, Southwest Medical University, Luzhou, Sichuan, China.
Nie Z; School of Public Health, Southwest Medical University, Luzhou, Sichuan, China.
Xu W; School of Public Health, Southwest Medical University, Luzhou, Sichuan, China.
Liu L; Department of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, Philadelphia, PA, USA.
Jia H; School of Public Health, Southwest Medical University, Luzhou, Sichuan, China. jhong_.; Center for Evidence-based Medicine, Southwest Medical University, Luzhou, China. jhong_.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jan 25; Vol. 12 (1), pp. 1356. Date of Electronic Publication: 2022 Jan 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hyperuricemia*/genetics
Hyperuricemia*/metabolism
ATP Binding Cassette Transporter, Subfamily G, Member 2/*genetics
Neoplasm Proteins/*genetics
Adult ; Aged ; Aged, 80 and over ; Cross-Sectional Studies ; Female ; Genetic Predisposition to Disease ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Risk Factors ; Young Adult

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Skocz do pozycji: 10.

Tytuł:: Cannabis constituents interact at the drug efflux pump BCRP to markedly increase plasma cannabidiolic acid concentrations.
Autorzy:: Anderson LL; Brain and Mind Centre, Discipline of Pharmacology, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.; Lambert Initiative for Cannabinoid Therapeutics, Brain and Mind Centre, The University of Sydney, 94 Mallett St, Camperdown, NSW, 2050, Australia.
Etchart MG; Lambert Initiative for Cannabinoid Therapeutics, Brain and Mind Centre, The University of Sydney, 94 Mallett St, Camperdown, NSW, 2050, Australia.
Bahceci D; Brain and Mind Centre, Discipline of Pharmacology, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
Golembiewski TA; Brain and Mind Centre, Discipline of Pharmacology, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
Arnold JC; Brain and Mind Centre, Discipline of Pharmacology, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia. .; Lambert Initiative for Cannabinoid Therapeutics, Brain and Mind Centre, The University of Sydney, 94 Mallett St, Camperdown, NSW, 2050, Australia. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jul 22; Vol. 11 (1), pp. 14948. Date of Electronic Publication: 2021 Jul 22.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: ATP Binding Cassette Transporter, Subfamily G, Member 2/*metabolism
Cannabinoids/*administration & dosage
Cannabis/*chemistry
Plant Oils/*administration & dosage
Administration, Oral ; Animals ; Biological Availability ; Cannabinoids/blood ; Cannabinoids/chemistry ; Cannabinoids/pharmacokinetics ; Dietary Supplements ; Dogs ; Madin Darby Canine Kidney Cells ; Mice ; Models, Animal ; Plant Oils/chemistry ; Plant Oils/pharmacokinetics

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Skocz do pozycji: 11.

Tytuł:: Circulating intestine-derived exosomal miR-328 in plasma, a possible biomarker for estimating BCRP function in the human intestines.
Autorzy:: Gotanda K; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Hirota T; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Saito J; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Fukae M; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Egashira Y; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Izumi N; SOUSEIKAI Global Clinical Research Center, Fukuoka, Japan.
Deguchi M; SOUSEIKAI Global Clinical Research Center, Fukuoka, Japan.
Kimura M; SOUSEIKAI Global Clinical Research Center, Fukuoka, Japan.
Matsuki S; SOUSEIKAI Global Clinical Research Center, Fukuoka, Japan.
Irie S; SOUSEIKAI Global Clinical Research Center, Fukuoka, Japan.
Ieiri I; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Aug 30; Vol. 6, pp. 32299. Date of Electronic Publication: 2016 Aug 30.
Typ publikacji:: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: ATP Binding Cassette Transporter, Subfamily G, Member 2/*genetics
Exosomes/*genetics
Intestinal Mucosa/*metabolism
MicroRNAs/*genetics
Neoplasm Proteins/*genetics
Sulfasalazine/*pharmacokinetics
ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Anti-Infective Agents/blood ; Anti-Infective Agents/pharmacokinetics ; Area Under Curve ; Arylamine N-Acetyltransferase/genetics ; Arylamine N-Acetyltransferase/metabolism ; Biomarkers/blood ; Exosomes/ultrastructure ; Gene Expression ; Genotype ; Humans ; MicroRNAs/blood ; Microscopy, Electron, Transmission ; Neoplasm Proteins/metabolism ; Polymorphism, Single Nucleotide ; Sulfasalazine/blood ; Young Adult

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Skocz do pozycji: 12.

Tytuł:: Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue.
Autorzy:: Cederbye CN; Faculty of Health and Medical Sciences, Department of Veterinary Disease Biology, Section for Molecular Disease Biology, University of Copenhagen, Strandboulevarden 49, DK- 2100 Copenhagen Ø, Denmark.
Palshof JA; Department of Oncology, Herlev and Gentofte Hospital, University of Copenhagen, Herlev Ringvej 75, DK-2730 Herlev, Denmark.
Hansen TP; Department of Pathology, Hvidovre Hospital, Kettegaard Alle 30, DK- 2650 Hvidovre, Denmark.
Duun-Henriksen AK; Danish Cancer Society, Strandboulevarden 49, DK- 2100 Copenhagen Ø, Denmark.
Linnemann D; Department of Pathology, Herlev and Gentofte Hospital, University of Copenhagen, Herlev Ringvej 75, DK-2730 Herlev, Denmark.
Stenvang J; Faculty of Health and Medical Sciences, Department of Veterinary Disease Biology, Section for Molecular Disease Biology, University of Copenhagen, Strandboulevarden 49, DK- 2100 Copenhagen Ø, Denmark.
Nielsen DL; Department of Oncology, Herlev and Gentofte Hospital, University of Copenhagen, Herlev Ringvej 75, DK-2730 Herlev, Denmark.
Brünner N; Faculty of Health and Medical Sciences, Department of Veterinary Disease Biology, Section for Molecular Disease Biology, University of Copenhagen, Strandboulevarden 49, DK- 2100 Copenhagen Ø, Denmark.
Viuff BM; Faculty of Health and Medical Sciences, Department of Veterinary Disease Biology, Section for Molecular Disease Biology, University of Copenhagen, Strandboulevarden 49, DK- 2100 Copenhagen Ø, Denmark.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Jun 03; Vol. 6, pp. 26997. Date of Electronic Publication: 2016 Jun 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:: ATP Binding Cassette Transporter, Subfamily G, Member 2/*metabolism
Antibodies, Monoclonal, Murine-Derived/*chemistry
Biomarkers, Tumor/*metabolism
Colonic Neoplasms/*metabolism
Neoplasm Proteins/*metabolism
ATP Binding Cassette Transporter, Subfamily G, Member 2/immunology ; Antibodies, Monoclonal, Murine-Derived/immunology ; Antibody Specificity ; Biomarkers, Tumor/immunology ; Cell Line, Tumor ; Colonic Neoplasms/diagnosis ; Cross Reactions ; Down-Regulation ; Fixatives/chemistry ; Formaldehyde/chemistry ; Humans ; Immunohistochemistry ; Neoplasm Proteins/immunology ; Paraffin Embedding ; RNA Interference ; RNA, Small Interfering/genetics ; Tissue Fixation

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Skocz do pozycji: 13.

Tytuł:: Bioengineered kidney tubules efficiently excrete uremic toxins.
Autorzy:: Jansen J; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.; Physiology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.; Department of Pediatrics, Radboud university medical center, Nijmegen, The Netherlands.; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands.
Fedecostante M; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.; Physiology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.; Department of Pediatrics, Radboud university medical center, Nijmegen, The Netherlands.; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands.
Wilmer MJ; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.
Peters JG; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.
Kreuser UM; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.
van den Broek PH; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.
Mensink RA; Cluster for Molecular Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands.
Boltje TJ; Cluster for Molecular Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands.
Stamatialis D; Department of Biomaterials Science and Technology, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, The Netherlands.
Wetzels JF; Nephrology, Radboud university medical center, Nijmegen, The Netherlands.
van den Heuvel LP; Department of Pediatrics, Radboud university medical center, Nijmegen, The Netherlands.; Department of Pediatric Nephrology &Growth and Regeneration, Catholic University Leuven, Leuven, Belgium.
Hoenderop JG; Physiology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.
Masereeuw R; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 May 31; Vol. 6, pp. 26715. Date of Electronic Publication: 2016 May 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Tissue Engineering*
ATP Binding Cassette Transporter, Subfamily G, Member 2/*metabolism
Kidney Tubules, Proximal/*metabolism
Multidrug Resistance-Associated Proteins/*metabolism
Neoplasm Proteins/*metabolism
Organic Anion Transport Protein 1/*metabolism
ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics ; Cell Line ; Humans ; Kidney Failure, Chronic/genetics ; Kidney Failure, Chronic/metabolism ; Kidney Failure, Chronic/pathology ; Kidney Tubules, Proximal/pathology ; Multidrug Resistance-Associated Proteins/genetics ; Neoplasm Proteins/genetics ; Organic Anion Transport Protein 1/genetics

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Skocz do pozycji: 14.

Tytuł:: Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles.
Autorzy:: Kita DH; Pharmaceutical Sciences Graduate Program, Laboratory of Cancer Drug Resistance, Federal University of Parana, Curitiba, PR, 80210-170, Brazil.; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Guragossian N; EA 4446 Bioactive Molecules and Medicinal Chemistry, Faculté de Pharmacie - ISPB, SFR Santé Lyon-Est CNRS UMS3453 - INSERM US7, Université Claude Bernard Lyon 1, Univ Lyon, 69373, Lyon, France.
Zattoni IF; Pharmaceutical Sciences Graduate Program, Laboratory of Cancer Drug Resistance, Federal University of Parana, Curitiba, PR, 80210-170, Brazil.
Moure VR; Pharmaceutical Sciences Graduate Program, Laboratory of Cancer Drug Resistance, Federal University of Parana, Curitiba, PR, 80210-170, Brazil.; Department of Clinical Analysis, Federal University of Parana, Curitiba, PR, 80210-170, Brazil.
Rego FGM; Department of Clinical Analysis, Federal University of Parana, Curitiba, PR, 80210-170, Brazil.
Lusvarghi S; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Moulenat T; EA 4446 Bioactive Molecules and Medicinal Chemistry, Faculté de Pharmacie - ISPB, SFR Santé Lyon-Est CNRS UMS3453 - INSERM US7, Université Claude Bernard Lyon 1, Univ Lyon, 69373, Lyon, France.
Belhani B; Laboratory of Applied Organic Chemistry, Synthesis of Biomolecules and Molecular Modelling Group, Badji-Mokhtar-Annaba University, Box 12, 23000, Annaba, Algeria.
Picheth G; Department of Clinical Analysis, Federal University of Parana, Curitiba, PR, 80210-170, Brazil.
Bouacida S; Département Sciences de la Matière, Faculté des Sciences exactes et Sciences de la nature et de la vie, Université Larbi Ben M'hidi, Oum El Bouaghi, Algeria.; Research Unit for Chemistry of the Environment and Molecular Structural, University of Constantine 1, Constantine, Algeria.
Bouaziz Z; EA 4446 Bioactive Molecules and Medicinal Chemistry, Faculté de Pharmacie - ISPB, SFR Santé Lyon-Est CNRS UMS3453 - INSERM US7, Université Claude Bernard Lyon 1, Univ Lyon, 69373, Lyon, France.
Marminon C; EA 4446 Bioactive Molecules and Medicinal Chemistry, Faculté de Pharmacie - ISPB, SFR Santé Lyon-Est CNRS UMS3453 - INSERM US7, Université Claude Bernard Lyon 1, Univ Lyon, 69373, Lyon, France.; Small Molecules for Biological Targets Team, Centre de recherche en cancérologie de Lyon, Centre Léon Bérard, CNRS 5286, INSERM 1052, Université Claude Bernard Lyon 1, Univ Lyon, 69373, Lyon, France.
Berredjem M; Laboratory of Applied Organic Chemistry, Synthesis of Biomolecules and Molecular Modelling Group, Badji-Mokhtar-Annaba University, Box 12, 23000, Annaba, Algeria.
Jose J; Institut für Pharmazeutische und Medizinische Chemie, PharmaCampus, Westfälische Wilhelms-Universität Münster, Corrensstr. 48, 48149, Münster, Germany.
Gonçalves MB; Department of Physics, Federal Technological University of Paraná, Curitiba, PR, 80230-901, Brazil.
Ambudkar SV; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Valdameri G; Pharmaceutical Sciences Graduate Program, Laboratory of Cancer Drug Resistance, Federal University of Parana, Curitiba, PR, 80210-170, Brazil. .; Department of Clinical Analysis, Federal University of Parana, Curitiba, PR, 80210-170, Brazil. .
Le Borgne M; EA 4446 Bioactive Molecules and Medicinal Chemistry, Faculté de Pharmacie - ISPB, SFR Santé Lyon-Est CNRS UMS3453 - INSERM US7, Université Claude Bernard Lyon 1, Univ Lyon, 69373, Lyon, France. .; Small Molecules for Biological Targets Team, Centre de recherche en cancérologie de Lyon, Centre Léon Bérard, CNRS 5286, INSERM 1052, Université Claude Bernard Lyon 1, Univ Lyon, 69373, Lyon, France. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jan 19; Vol. 11 (1), pp. 1788. Date of Electronic Publication: 2021 Jan 19.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: ATP Binding Cassette Transporter, Subfamily G, Member 2/*antagonists & inhibitors
Breast Neoplasms/*metabolism
Indoles/*pharmacology
Neoplasm Proteins/*antagonists & inhibitors
Antineoplastic Agents/therapeutic use ; Breast Neoplasms/drug therapy ; Cell Survival/drug effects ; Female ; HEK293 Cells ; Humans ; Indoles/chemistry ; Structure-Activity Relationship

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Skocz do pozycji: 15.

Tytuł:: Genome wide association study of uric acid in Indian population and interaction of identified variants with Type 2 diabetes.
Autorzy:: Giri AK; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi 110020, India.; Academy of Scientific and Innovative Research, CSIR-Institute of Genomics and Integrative Biology Campus, New Delhi - 110020, India.
Banerjee P; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi 110020, India.
Chakraborty S; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi 110020, India.; Academy of Scientific and Innovative Research, CSIR-Institute of Genomics and Integrative Biology Campus, New Delhi - 110020, India.
Kauser Y; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi 110020, India.; Academy of Scientific and Innovative Research, CSIR-Institute of Genomics and Integrative Biology Campus, New Delhi - 110020, India.
Undru A; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi 110020, India.; Academy of Scientific and Innovative Research, CSIR-Institute of Genomics and Integrative Biology Campus, New Delhi - 110020, India.
Roy S; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi 110020, India.
Parekatt V; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi 110020, India.
Ghosh S; Human Genetics Unit, Indian Statistical Institute, Kolkata - 700108, India.
Tandon N; Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi 110029, India.
Bharadwaj D; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi 110020, India.; Academy of Scientific and Innovative Research, CSIR-Institute of Genomics and Integrative Biology Campus, New Delhi - 110020, India.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Feb 23; Vol. 6, pp. 21440. Date of Electronic Publication: 2016 Feb 23.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
MeSH Terms:: Polymorphism, Single Nucleotide*
ATP Binding Cassette Transporter, Subfamily G, Member 2/*genetics
Diabetes Mellitus, Type 2/*genetics
Glucose Transport Proteins, Facilitative/*genetics
Neoplasm Proteins/*genetics
Organic Anion Transporters, Sodium-Independent/*genetics
RNA, Long Noncoding/*genetics
ATP Binding Cassette Transporter, Subfamily G, Member 2/blood ; Adult ; Case-Control Studies ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/physiopathology ; Female ; Gene Expression Regulation ; Genome, Human ; Genome-Wide Association Study ; Glucose Transport Proteins, Facilitative/blood ; Humans ; India ; Male ; Neoplasm Proteins/blood ; Organic Anion Transporters, Sodium-Independent/blood ; RNA, Long Noncoding/blood ; Uric Acid/blood

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Skocz do pozycji: 16.

Tytuł:: Influence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects.
Autorzy:: Kim Y; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Yoon S; Clinical Trials Center, Seoul National University College of Medicine and Bundang Hospital, Seongnam, Korea.
Choi Y; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Yoon SH; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Cho JY; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Jang IJ; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Yu KS; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Chung JY; Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Bundang Hospital, Seongnam, Korea. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Dec 19; Vol. 9 (1), pp. 19410. Date of Electronic Publication: 2019 Dec 19.
Typ publikacji:: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: ATP Binding Cassette Transporter, Subfamily G, Member 2/*genetics
Liver-Specific Organic Anion Transporter 1/*genetics
Neoplasm Proteins/*genetics
Polymorphism, Single Nucleotide/*genetics
Rosuvastatin Calcium/*pharmacokinetics
Rosuvastatin Calcium/*pharmacology
Administration, Oral ; Adult ; Aged ; Aged, 80 and over ; Area Under Curve ; Female ; Humans ; Male ; Phenotype ; Republic of Korea ; Rosuvastatin Calcium/administration & dosage ; Rosuvastatin Calcium/blood

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Skocz do pozycji: 17.

Tytuł:: Fine mapping and identification of serum urate loci in American Indians: The Strong Heart Family Study.
Autorzy:: Chittoor G; Department of Nutrition, and UNC Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC, USA.; Biomedical and Translational Informatics, Geisinger, Danville, PA, USA.
Haack K; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX, USA.
Balakrishnan P; Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA.
Bizon C; Renaissance Computing Institute, University of North Carolina, Chapel Hill, NC, USA.
Laston S; South Texas Diabetes and Obesity Institute, School of Medicine, University of Texas Rio Grande Valley, Brownsville, TX, USA.
Best LG; Missouri Breaks Industries Research Inc., Eagle Butte, SD, USA.
MacCluer JW; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX, USA.
North KE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Umans JG; Medstar Health Research Institute, Hyattsville, MD, USA.
Franceschini N; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Prasad G; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi, 110 020, India.; Academy of Scientific and Innovative Research, CSIR-Institute of Genomics and Integrative Biology Campus, New Delhi, 110 020, India.
Macias-Kauffer L; Laboratorio de Enfermedades Cardiovasculares, INMEGEN, Mexico City, 14610, Mexico.
Villarreal-Molina T; Laboratorio de Enfermedades Cardiovasculares, INMEGEN, Mexico City, 14610, Mexico.
Bharadwaj D; Academy of Scientific and Innovative Research, CSIR-Institute of Genomics and Integrative Biology Campus, New Delhi, 110 020, India.; Systems Genomics Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110 067, India.
Canizales-Quinteros S; Unidad de Genomica de Poblaciones Aplicada a la Salud Facultad de Quimica, UNAM-Instituto Nacional de Medicina Genomica, Mexico City, Mexico.
Navas-Acien A; Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA.
Cole SA; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX, USA.
Voruganti VS; Department of Nutrition, and UNC Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Nov 29; Vol. 9 (1), pp. 17899. Date of Electronic Publication: 2019 Nov 29.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: ATP Binding Cassette Transporter, Subfamily G, Member 2/*genetics
Glucose Transport Proteins, Facilitative/*genetics
Heart/*physiology
Neoplasm Proteins/*genetics
Uric Acid/*blood
American Indian or Alaska Native/*genetics
Adult ; Alleles ; Databases, Genetic ; Female ; Gene Frequency ; Genetic Loci ; Genome-Wide Association Study ; Genotype ; Humans ; Linkage Disequilibrium ; Nucleobindins/genetics ; Polymorphism, Single Nucleotide

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Skocz do pozycji: 18.

Tytuł:: Influence of CYP3A4/5 and ABC transporter polymorphisms on lenvatinib plasma trough concentrations in Japanese patients with thyroid cancer.
Autorzy:: Ozeki T; Department of Pharmacy, Akita University Hospital, Akita, Japan.
Nagahama M; Department of Surgery, Ito Hospital, Tokyo, Japan.
Fujita K; Department of Pharmacy, Akita University Hospital, Akita, Japan.
Suzuki A; Department of Surgery, Ito Hospital, Tokyo, Japan.
Sugino K; Department of Surgery, Ito Hospital, Tokyo, Japan.
Ito K; Department of Surgery, Ito Hospital, Tokyo, Japan.
Miura M; Department of Pharmacy, Akita University Hospital, Akita, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Apr 01; Vol. 9 (1), pp. 5404. Date of Electronic Publication: 2019 Apr 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Polymorphism, Single Nucleotide*
ATP Binding Cassette Transporter, Subfamily G, Member 2/*genetics
Cytochrome P-450 CYP3A/*genetics
Phenylurea Compounds/*therapeutic use
Quinolines/*therapeutic use
Thyroid Neoplasms/*genetics
ATP Binding Cassette Transporter, Subfamily B/genetics ; Adult ; Aged ; Alleles ; Asian People/genetics ; Female ; Gene Frequency ; Genotype ; Humans ; Japan ; Male ; Middle Aged ; Multidrug Resistance-Associated Protein 2 ; Phenylurea Compounds/blood ; Phenylurea Compounds/pharmacokinetics ; Protein Kinase Inhibitors/blood ; Protein Kinase Inhibitors/pharmacokinetics ; Protein Kinase Inhibitors/therapeutic use ; Quinolines/blood ; Quinolines/pharmacokinetics ; Regression Analysis ; Thyroid Neoplasms/drug therapy ; Thyroid Neoplasms/ethnology

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Skocz do pozycji: 19.

Tytuł:: Hyperthermia enhances photodynamic therapy by regulation of HCP1 and ABCG2 expressions via high level ROS generation.
Autorzy:: Kurokawa H; Faculty of Medicine, University of Tsukuba, 305-8575, Ibaraki, Japan.
Ito H; Graduate School of Medical and Dental Sciences, Kagoshima University, 890-8544, Kagoshima, Japan.
Terasaki M; Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Ten-nohdai, Tsukuba, Ibaraki, 305-8575, Japan.
Matsui H; Faculty of Medicine, University of Tsukuba, 305-8575, Ibaraki, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Feb 07; Vol. 9 (1), pp. 1638. Date of Electronic Publication: 2019 Feb 07.
Typ publikacji:: Journal Article
MeSH Terms:: Hyperthermia, Induced/*methods
Photochemotherapy/*methods
Proton-Coupled Folate Transporter/*metabolism
Stomach Neoplasms/*therapy
ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Acetylcysteine/pharmacology ; Animals ; Cell Line ; Cell Line, Tumor ; Doxorubicin/pharmacology ; Mitochondria/metabolism ; Mitochondria/pathology ; Protein-Arginine N-Methyltransferases/metabolism ; Rats ; Reactive Oxygen Species/metabolism ; Stomach Neoplasms/metabolism ; Stomach Neoplasms/pathology

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Skocz do pozycji: 20.

Tytuł:: Comparative study of substrate free and amniotic membrane scaffolds for cultivation of limbal epithelial sheet.
Autorzy:: Lee HJ; Department of Biochemical Engineering, Seoil University, Seoul, Korea.
Nam SM; Department of Ophthalmology, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Choi SK; Department of Obstetrics and Gynecology, Incheon St. Mary's Hospital, Incheon, Korea.
Seo KY; Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.
Kim HO; Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.
Chung SH; Department of Ophthalmology and Visual Science, Catholic Institute of Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2018 Oct 02; Vol. 8 (1), pp. 14628. Date of Electronic Publication: 2018 Oct 02.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Culture Media, Serum-Free/*chemistry
Epithelium, Corneal/*growth & development
Limbus Corneae/*growth & development
Tissue Culture Techniques/*methods
Tissue Scaffolds/*chemistry
ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Animals ; Corneal Transplantation ; Humans ; Keratin-15/metabolism ; Neoplasm Proteins/metabolism ; Rabbits ; Transcription Factors/metabolism ; Tumor Suppressor Proteins/metabolism

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