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Wyszukujesz frazę ""ATP Binding Cassette Transporter 1"" wg kryterium: Temat


Tytuł :
Nascent HDL (High-Density Lipoprotein) Discs Carry Cholesterol to HDL Spheres: Effects of HDL Particle Remodeling on Cholesterol Efflux.
Autorzy :
Navdaev AV; From the CSL Behring AG, Bern, Switzerland (A.V.N., L.S., S.A.D.).
Sborgi L; From the CSL Behring AG, Bern, Switzerland (A.V.N., L.S., S.A.D.).
Wright SD; CSL Behring, King of Prussia, PA (S.D.W.).
Didichenko SA; From the CSL Behring AG, Bern, Switzerland (A.V.N., L.S., S.A.D.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 May; Vol. 40 (5), pp. 1182-1194. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP Binding Cassette Transporter 1/*metabolism
Cholesterol, HDL/*blood
Macrophages/*metabolism
ATP Binding Cassette Transporter 1/genetics ; Animals ; Apolipoprotein A-I/blood ; Biological Transport ; Cholesterol, HDL/chemistry ; Humans ; Kinetics ; Lipoproteins, HDL/blood ; Mice ; Particle Size ; RAW 264.7 Cells
Czasopismo naukowe
Tytuł :
Cultured macrophages transfer surplus cholesterol into adjacent cells in the absence of serum or high-density lipoproteins.
Autorzy :
He C; Department of Medicine, University of California, Los Angeles, CA 90095.
Jiang H; School of Molecular Sciences, University of Western Australia, 6009 Perth, Australia.
Song W; Department of Medicine, University of California, Los Angeles, CA 90095.
Riezman H; Department of Biochemistry, University of Geneva, CH-1211 Geneva 4, Switzerland.; National Centre of Competence in Research, Chemical Biology, University of Geneva, CH-1211 Geneva 4, Switzerland.
Tontonoz P; Department of Human Genetics, University of California, Los Angeles, CA 90095.
Weston TA; Department of Medicine, University of California, Los Angeles, CA 90095.
Guagliardo P; Centre for Microscopy, Characterisation and Analysis, University of Western Australia, 6009 Perth, Australia.
Kim PH; Department of Medicine, University of California, Los Angeles, CA 90095.
Jung R; Department of Medicine, University of California, Los Angeles, CA 90095.
Heizer P; Department of Medicine, University of California, Los Angeles, CA 90095.
Fong LG; Department of Medicine, University of California, Los Angeles, CA 90095; .
Young SG; Department of Medicine, University of California, Los Angeles, CA 90095; .; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90095.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 May 12; Vol. 117 (19), pp. 10476-10483. Date of Electronic Publication: 2020 Apr 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP Binding Cassette Transporter 1/*metabolism
Cholesterol/*metabolism
Macrophages/*metabolism
ATP Binding Cassette Transporter 1/physiology ; ATP-Binding Cassette Transporters/metabolism ; Animals ; Atherosclerosis/metabolism ; Atherosclerosis/physiopathology ; Biological Transport ; Foam Cells/metabolism ; Lipid Metabolism ; Lipoproteins, HDL/metabolism ; Macrophages/physiology ; Macrophages, Peritoneal/metabolism ; Mice ; Mice, Inbred C57BL ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Serum/metabolism ; beta-Cyclodextrins/metabolism
Czasopismo naukowe
Tytuł :
C-terminal of ABCA1 separately regulates cholesterol floppase activity and cholesterol efflux activity.
Autorzy :
Okamoto Y; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
Tomioka M; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
Ogasawara F; Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Kyoto, Japan.
Nagaiwa K; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
Kimura Y; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
Kioka N; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.; Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Kyoto, Japan.
Ueda K; Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Kyoto, Japan.
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Źródło :
Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2020 Apr; Vol. 84 (4), pp. 764-773. Date of Electronic Publication: 2019 Dec 09.
Typ publikacji :
Journal Article
MeSH Terms :
ATP Binding Cassette Transporter 1/*metabolism
Cholesterol/*metabolism
ATP Binding Cassette Transporter 1/chemistry ; Amino Acid Sequence ; Biological Transport ; Conserved Sequence ; HEK293 Cells ; Humans ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł :
PRMT2 inhibits the formation of foam cell induced by ox-LDL in RAW 264.7 macrophage involving ABCA1 mediated cholesterol efflux.
Autorzy :
Li YY; Institute of Clinical Medicine, First Affiliated Hospital of University of South China, Hengyang, 421001, Hunan, PR China; Department of Cardiovascular Medicine, First Affiliated Hospital of University of South China, Hengyang, 421001, Hunan, PR China.
Zhou SH; Department of Physiology, Basic Medical College, Guilin Medical University, Guilin, 541199, Guangxi, China; Guangxi Key Laboratory of Brain and Cognitive Neuroscience, Guilin Medical University, Guilin, 541199, Guangxi, PR China.
Chen SS; Department of Physiology, Hengyang Medical College, University of South China, Hengyang, 421001, Hunan, PR China.
Zhong J; Institute of Clinical Medicine, First Affiliated Hospital of University of South China, Hengyang, 421001, Hunan, PR China. Electronic address: .
Wen GB; Institute of Clinical Medicine, First Affiliated Hospital of University of South China, Hengyang, 421001, Hunan, PR China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Mar 26; Vol. 524 (1), pp. 77-82. Date of Electronic Publication: 2020 Jan 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP Binding Cassette Transporter 1/*metabolism
Foam Cells/*metabolism
Lipoproteins, LDL/*metabolism
Protein-Arginine N-Methyltransferases/*metabolism
ATP Binding Cassette Transporter 1/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 1/metabolism ; Animals ; Arginine/metabolism ; Atherosclerosis/metabolism ; Biological Transport ; CD36 Antigens/metabolism ; Gene Expression Regulation ; Lentivirus/genetics ; Methylation ; Mice ; RAW 264.7 Cells ; RNA, Messenger/metabolism ; Receptors, Scavenger/metabolism ; Transfection
Czasopismo naukowe
Tytuł :
Preventing Calpain Externalization by Reducing ABCA1 Activity with Probenecid Limits Melanoma Angiogenesis and Development.
Autorzy :
Hanouna G; Sorbonne Universités, Université Pierre et Marie Curie, Univ Paris 06, UMR_S 1155 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Paris, France; Institut National de la Santé et de la Recherche Médicale, UMR_S 1155, Paris, France.
Tang E; Sorbonne Universités, Université Pierre et Marie Curie, Univ Paris 06, UMR_S 1155 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Paris, France; Institut National de la Santé et de la Recherche Médicale, UMR_S 1155, Paris, France.
Perez J; Sorbonne Universités, Université Pierre et Marie Curie, Univ Paris 06, UMR_S 1155 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Paris, France; Institut National de la Santé et de la Recherche Médicale, UMR_S 1155, Paris, France.
Vandermeersch S; Sorbonne Universités, Université Pierre et Marie Curie, Univ Paris 06, UMR_S 1155 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Paris, France; Institut National de la Santé et de la Recherche Médicale, UMR_S 1155, Paris, France.
Haymann JP; Sorbonne Universités, Université Pierre et Marie Curie, Univ Paris 06, UMR_S 1155 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Paris, France; Institut National de la Santé et de la Recherche Médicale, UMR_S 1155, Paris, France; Assistance Publique - Hôpitaux de Paris, Hôpital Tenon, Paris, France.
Baud L; Sorbonne Universités, Université Pierre et Marie Curie, Univ Paris 06, UMR_S 1155 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Paris, France; Institut National de la Santé et de la Recherche Médicale, UMR_S 1155, Paris, France; Assistance Publique - Hôpitaux de Paris, Hôpital Tenon, Paris, France.
Letavernier E; Sorbonne Universités, Université Pierre et Marie Curie, Univ Paris 06, UMR_S 1155 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Paris, France; Institut National de la Santé et de la Recherche Médicale, UMR_S 1155, Paris, France; Assistance Publique - Hôpitaux de Paris, Hôpital Tenon, Paris, France. Electronic address: .
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Źródło :
The Journal of investigative dermatology [J Invest Dermatol] 2020 Feb; Vol. 140 (2), pp. 445-454. Date of Electronic Publication: 2019 Aug 16.
Typ publikacji :
Journal Article
MeSH Terms :
ATP Binding Cassette Transporter 1/*antagonists & inhibitors
Calpain/*metabolism
Melanoma, Experimental/*drug therapy
Neovascularization, Pathologic/*drug therapy
Probenecid/*pharmacology
Skin Neoplasms/*drug therapy
ATP Binding Cassette Transporter 1/genetics ; ATP Binding Cassette Transporter 1/metabolism ; Animals ; Calcium-Binding Proteins/genetics ; Calcium-Binding Proteins/metabolism ; Cell Line, Tumor/transplantation ; Cell Proliferation/drug effects ; Humans ; Male ; Melanoma, Experimental/blood supply ; Melanoma, Experimental/pathology ; Mice ; Mice, Transgenic ; Neovascularization, Pathologic/pathology ; Probenecid/therapeutic use ; Skin Neoplasms/blood supply ; Skin Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Midkine Inhibits Cholesterol Efflux by Decreasing ATP-Binding Membrane Cassette Transport Protein A1 via Adenosine Monophosphate-Activated Protein Kinase/Mammalian Target of Rapamycin Signaling in Macrophages.
Autorzy :
Ou HX; Hunan Province Innovative Training Base for Medical Postgraduates, University of South China and Yueyang Women & Children's Medical Center.; Center for Diabetic Systems Medicine, Guangxi Key Laboratory of Excellence, Guilin Medical University.
Huang Q; Hunan Province Innovative Training Base for Medical Postgraduates, University of South China and Yueyang Women & Children's Medical Center.
Liu CH; Clinical Anatomy & Reproductive Medicine Application Institute, University of South China.
Xiao J; Department of Anesthesiology, the Second Affiliated Hospital, University of South China.
Lv YC; Hunan Province Innovative Training Base for Medical Postgraduates, University of South China and Yueyang Women & Children's Medical Center.; Center for Diabetic Systems Medicine, Guangxi Key Laboratory of Excellence, Guilin Medical University.; Clinical Anatomy & Reproductive Medicine Application Institute, University of South China.
Li X; Hunan Province Innovative Training Base for Medical Postgraduates, University of South China and Yueyang Women & Children's Medical Center.
Lei LP; Department of Anesthesiology, the Second Affiliated Hospital, University of South China.
Mo ZC; Center for Diabetic Systems Medicine, Guangxi Key Laboratory of Excellence, Guilin Medical University.; Clinical Anatomy & Reproductive Medicine Application Institute, University of South China.
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Źródło :
Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2020 Jan 24; Vol. 84 (2), pp. 217-225. Date of Electronic Publication: 2020 Jan 09.
Typ publikacji :
Journal Article
MeSH Terms :
AMP-Activated Protein Kinases/*metabolism
ATP Binding Cassette Transporter 1/*metabolism
Cholesterol/*metabolism
Macrophages/*drug effects
Midkine/*pharmacology
TOR Serine-Threonine Kinases/*metabolism
ATP Binding Cassette Transporter 1/genetics ; Animals ; Down-Regulation ; Enzyme Activation ; Macrophages/enzymology ; Mice ; Phosphorylation ; RAW 264.7 Cells ; Signal Transduction
Czasopismo naukowe
Tytuł :
First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation.
Autorzy :
Brubaker G; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio, United States of America.
Lorkowski SW; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio, United States of America.
Gulshan K; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio, United States of America.
Hazen SL; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio, United States of America.; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, United States of America.
Gogonea V; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio, United States of America.; Department of Chemistry, Cleveland State University, Cleveland, Ohio, United States of America.
Smith JD; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio, United States of America.; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Jan 16; Vol. 15 (1), pp. e0221915. Date of Electronic Publication: 2020 Jan 16 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP Binding Cassette Transporter 1/*genetics
Apolipoprotein A-I/*genetics
Lipid Metabolism/*genetics
Lipids/*chemistry
ATP Binding Cassette Transporter 1/chemistry ; ATP-Binding Cassette Transporters/genetics ; Animals ; Apolipoprotein A-I/chemistry ; Biological Transport/genetics ; Circular Dichroism ; Crystallography, X-Ray ; Humans ; Kinetics ; Lipids/genetics ; Mice ; Mutagenesis, Site-Directed ; Protein Binding ; Protein Structure, Secondary ; Protein Unfolding ; RAW 264.7 Cells ; Sequence Deletion/genetics
Czasopismo naukowe
Tytuł :
High dose rosuvastatin increases ABCA1 transporter in human atherosclerotic plaques in a cholesterol-independent fashion.
Autorzy :
Santovito D; Clinical Research Center, Center of Excellence on Aging, Ce.S.I.-Me.T. 'G. d'Annunzio University' Foundation, Chieti, Italy; Department of Medicine and Aging, 'G. d'Annunzio' University, Chieti, Italy; Internal Medicine Department, European Center of Excellence on Atherosclerosis, Hypertension and Dyslipidemia, SS Annunziata Hospital, Chieti, Italy; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians University (LMU), Munich, Germany.
Marcantonio P; Clinical Research Center, Center of Excellence on Aging, Ce.S.I.-Me.T. 'G. d'Annunzio University' Foundation, Chieti, Italy; Department of Medicine and Aging, 'G. d'Annunzio' University, Chieti, Italy.
Mastroiacovo D; Angiology Unit, SS. Filippo and Nicola Hospital, Avezzano, L'Aquila, Italy.
Natarelli L; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians University (LMU), Munich, Germany.
Mandolini C; Clinical Research Center, Center of Excellence on Aging, Ce.S.I.-Me.T. 'G. d'Annunzio University' Foundation, Chieti, Italy; Department of Medicine and Aging, 'G. d'Annunzio' University, Chieti, Italy.
De Nardis V; Clinical Research Center, Center of Excellence on Aging, Ce.S.I.-Me.T. 'G. d'Annunzio University' Foundation, Chieti, Italy; Department of Medicine and Aging, 'G. d'Annunzio' University, Chieti, Italy.
Paganelli C; Clinical Research Center, Center of Excellence on Aging, Ce.S.I.-Me.T. 'G. d'Annunzio University' Foundation, Chieti, Italy; Department of Medicine and Aging, 'G. d'Annunzio' University, Chieti, Italy; Internal Medicine Department, European Center of Excellence on Atherosclerosis, Hypertension and Dyslipidemia, SS Annunziata Hospital, Chieti, Italy.
De Cesare D; Clinical Research Center, Center of Excellence on Aging, Ce.S.I.-Me.T. 'G. d'Annunzio University' Foundation, Chieti, Italy; Department of Medicine and Aging, 'G. d'Annunzio' University, Chieti, Italy.
Affaitati G; Clinical Research Center, Center of Excellence on Aging, Ce.S.I.-Me.T. 'G. d'Annunzio University' Foundation, Chieti, Italy; Department of Medicine and Aging, 'G. d'Annunzio' University, Chieti, Italy; Internal Medicine Department, European Center of Excellence on Atherosclerosis, Hypertension and Dyslipidemia, SS Annunziata Hospital, Chieti, Italy.
Giamberardino MA; Clinical Research Center, Center of Excellence on Aging, Ce.S.I.-Me.T. 'G. d'Annunzio University' Foundation, Chieti, Italy; Department of Medicine and Aging, 'G. d'Annunzio' University, Chieti, Italy; Internal Medicine Department, European Center of Excellence on Atherosclerosis, Hypertension and Dyslipidemia, SS Annunziata Hospital, Chieti, Italy.
Stellin L; Department of Medicine and Aging, 'G. d'Annunzio' University, Chieti, Italy.
Pinelli M; Angiology Unit, SS. Filippo and Nicola Hospital, Avezzano, L'Aquila, Italy.
Weber C; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians University (LMU), Munich, Germany.
De Blasis G; Unit of Vascular Surgery, SS. Filippo e Nicola Hospital, Avezzano, L'Aquila, Italy.
Occhiuzzi U; Clinical Pathology, SS. Filippo e Nicola Hospital, Avezzano, L'Aquila, Italy.
Bucci M; Clinical Research Center, Center of Excellence on Aging, Ce.S.I.-Me.T. 'G. d'Annunzio University' Foundation, Chieti, Italy; Department of Medicine and Aging, 'G. d'Annunzio' University, Chieti, Italy; Internal Medicine Department, European Center of Excellence on Atherosclerosis, Hypertension and Dyslipidemia, SS Annunziata Hospital, Chieti, Italy.
Desideri G; Geriatric Unit, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Cipollone F; Clinical Research Center, Center of Excellence on Aging, Ce.S.I.-Me.T. 'G. d'Annunzio University' Foundation, Chieti, Italy; Department of Medicine and Aging, 'G. d'Annunzio' University, Chieti, Italy; Internal Medicine Department, European Center of Excellence on Atherosclerosis, Hypertension and Dyslipidemia, SS Annunziata Hospital, Chieti, Italy. Electronic address: .
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Źródło :
International journal of cardiology [Int J Cardiol] 2020 Jan 15; Vol. 299, pp. 249-253. Date of Electronic Publication: 2019 Aug 03.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
ATP Binding Cassette Transporter 1/*blood
Cholesterol/*blood
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage
Plaque, Atherosclerotic/*blood
Plaque, Atherosclerotic/*drug therapy
Rosuvastatin Calcium/*administration & dosage
ATP Binding Cassette Transporter 1/biosynthesis ; Aged ; Aged, 80 and over ; Anticholesteremic Agents/administration & dosage ; Dose-Response Relationship, Drug ; Female ; Humans ; Male
Czasopismo naukowe
Tytuł :
Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression.
Autorzy :
Koga M; Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
Kanaoka Y; Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
Okamoto M; Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
Nakao Y; Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
Inada K; Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
Takayama S; Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
Kataoka Y; Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
Yamauchi A; Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan. Electronic address: .
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2020 Jan; Vol. 142 (1), pp. 9-15. Date of Electronic Publication: 2019 Nov 14.
Typ publikacji :
Journal Article
MeSH Terms :
ATP Binding Cassette Transporter 1/*metabolism
ATP Binding Cassette Transporter, Subfamily G, Member 1/*metabolism
Macrophages/*metabolism
Nicotine/*pharmacology
Plaque, Atherosclerotic/*etiology
Varenicline/*toxicity
ATP Binding Cassette Transporter 1/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 1/genetics ; Animals ; Down-Regulation ; Gene Expression Regulation/drug effects ; Lipoproteins, LDL/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout, ApoE ; Nicotine/agonists ; RAW 264.7 Cells ; Smoking Cessation Agents/toxicity
Czasopismo naukowe
Tytuł :
miR-33-5p knockdown attenuates abdominal aortic aneurysm progression via promoting target adenosine triphosphate-binding cassette transporter A1 expression and activating the PI3K/Akt signaling pathway.
Autorzy :
Zhao L; Department of Vascular Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, P.R. China.
Huang J; Cancer Center, The First Affiliated Hospital of Kunming Medical University, Kunming, P.R. China.
Zhu Y; Intensive Care Unit, The First Affiliated Hospital of Kunming Medical University, Kunming, P.R. China.
Han S; Department of Vascular Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, P.R. China.
Qing K; Department of Vascular Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, P.R. China.
Wang J; Department of Vascular Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, P.R. China.
Feng Y; Department of Vascular Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, P.R. China.
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Źródło :
Perfusion [Perfusion] 2020 Jan; Vol. 35 (1), pp. 57-65. Date of Electronic Publication: 2019 Jun 06.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Knockdown Techniques*
ATP Binding Cassette Transporter 1/*metabolism
Aorta, Abdominal/*enzymology
Aortic Aneurysm, Abdominal/*prevention & control
Foam Cells/*enzymology
MicroRNAs/*metabolism
Phosphatidylinositol 3-Kinase/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
ATP Binding Cassette Transporter 1/genetics ; Aged ; Aorta, Abdominal/pathology ; Aortic Aneurysm, Abdominal/enzymology ; Aortic Aneurysm, Abdominal/genetics ; Aortic Aneurysm, Abdominal/pathology ; Case-Control Studies ; Cholesterol/metabolism ; Cytokines/metabolism ; Disease Progression ; Female ; Foam Cells/pathology ; Humans ; Inflammation Mediators/metabolism ; Male ; MicroRNAs/genetics ; Middle Aged ; Signal Transduction ; THP-1 Cells ; Up-Regulation
Czasopismo naukowe
Tytuł :
Identification of a novel cholesterol-lowering dipeptide, phenylalanine-proline (FP), and its down-regulation of intestinal ABCA1 in hypercholesterolemic rats and Caco-2 cells.
Autorzy :
Banno A; Department of Applied Life Science, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.
Wang J; Department of Agriculture, College of Hetao, Bayannur, 015000, China.
Okada K; Department of Applied Life Science, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.
Mori R; Department of Applied Life Science, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.
Mijiti M; Department of Applied Life Science, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.
Nagaoka S; Department of Applied Life Science, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan. .
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Źródło :
Scientific reports [Sci Rep] 2019 Dec 19; Vol. 9 (1), pp. 19416. Date of Electronic Publication: 2019 Dec 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP Binding Cassette Transporter 1/*metabolism
Cholesterol/*blood
Dipeptides/*pharmacology
Down-Regulation/*drug effects
Hypercholesterolemia/*metabolism
Intestines/*physiology
ATP Binding Cassette Transporter 1/genetics ; Animals ; Caco-2 Cells ; Cattle ; Diet, High-Fat ; Gene Expression Regulation/drug effects ; Humans ; Hydrolysis ; Intestinal Absorption/drug effects ; Liver/metabolism ; Mice, Knockout ; Micelles ; Models, Biological ; Molecular Weight ; Promoter Regions, Genetic/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Solubility ; Ultrafiltration
Czasopismo naukowe
Tytuł :
Small GTPase Arf6 regulates diabetes-induced cholesterol accumulation in podocytes.
Autorzy :
Hu J; Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, China.
Yang Q; Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, China.
Chen Z; Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, China.
Liang W; Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, China.
Feng J; Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, China.
Ding G; Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, China.
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Źródło :
Journal of cellular physiology [J Cell Physiol] 2019 Dec; Vol. 234 (12), pp. 23559-23570. Date of Electronic Publication: 2019 Jun 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ADP-Ribosylation Factors/*metabolism
ATP Binding Cassette Transporter 1/*metabolism
Cholesterol/*metabolism
Diabetes Mellitus, Experimental/*enzymology
Diabetic Nephropathies/*enzymology
Podocytes/*enzymology
ADP-Ribosylation Factors/genetics ; ATP Binding Cassette Transporter 1/genetics ; Animals ; Biological Transport ; Blood Glucose/metabolism ; Cell Line ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/genetics ; Diabetes Mellitus, Experimental/pathology ; Diabetic Nephropathies/blood ; Diabetic Nephropathies/genetics ; Diabetic Nephropathies/pathology ; Humans ; Male ; Podocytes/pathology ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Phenotypic severity in a family with MEND syndrome is directly associated with the accumulation of potentially functional variants of cholesterol homeostasis genes.
Autorzy :
Barboza-Cerda MC; Facultad de Medicina y Hospital Universitario 'Dr. José E. González', Servicio de Anatomía Patológica y Citopatología, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.; Facultad de Medicina y Hospital Universitario 'Dr. José E. González', Departamento de Bioquímica y Medicina Molecular, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
Barboza-Quintana O; Facultad de Medicina y Hospital Universitario 'Dr. José E. González', Servicio de Anatomía Patológica y Citopatología, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
Martínez-Aldape G; Facultad de Medicina y Hospital Universitario 'Dr. José E. González', Servicio de Anatomía Patológica y Citopatología, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
Garza-Guajardo R; Facultad de Medicina y Hospital Universitario 'Dr. José E. González', Servicio de Anatomía Patológica y Citopatología, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
Déctor MA; Facultad de Medicina y Hospital Universitario 'Dr. José E. González', Servicio de Anatomía Patológica y Citopatología, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.; Facultad de Medicina y Hospital Universitario 'Dr. José E. González', Departamento de Bioquímica y Medicina Molecular, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
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Źródło :
Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2019 Sep; Vol. 7 (9), pp. e931. Date of Electronic Publication: 2019 Aug 08.
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP Binding Cassette Transporter 1*/genetics
ATP Binding Cassette Transporter 1*/metabolism
Apolipoprotein A-V*/genetics
Apolipoprotein A-V*/metabolism
Apolipoprotein B-100*/genetics
Apolipoprotein B-100*/metabolism
Cholesterol*/genetics
Cholesterol*/metabolism
Exome*
Polymorphism, Genetic*
Waardenburg Syndrome*/genetics
Waardenburg Syndrome*/metabolism
Waardenburg Syndrome*/pathology
Female ; Genetic Association Studies ; Homeostasis/genetics ; Humans ; Male ; Phenotype ; Severity of Illness Index
SCR Disease Name :
Van der Hoeve Halbertsma Waardenburg Gualdi Syndrome
Czasopismo naukowe
Tytuł :
ABCA1 plays an anti-inflammatory role by affecting TLR4 at the feto-maternal interface.
Autorzy :
Ding N; Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China.
Liu N; Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China.
Yang L; Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China.
Han X; Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China.
Lin L; Department of Gynecology and Obstetrics, Peking University International Hospital, Beijing 102206, China.
Long Y; Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118390. Date of Electronic Publication: 2020 Sep 05.
Typ publikacji :
Journal Article
MeSH Terms :
Maternal-Fetal Exchange*
ATP Binding Cassette Transporter 1/*metabolism
Toll-Like Receptor 4/*metabolism
Blotting, Western ; Cells, Cultured ; Chorion/metabolism ; Decidua/metabolism ; Enzyme-Linked Immunosorbent Assay ; Female ; Flow Cytometry ; Fluorescent Antibody Technique ; Humans ; Microscopy, Confocal ; Placenta/metabolism ; Pregnancy ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Defects in High Density Lipoprotein metabolism and hepatic steatosis in mice with liver-specific ablation of Hepatocyte Nuclear Factor 4A.
Autorzy :
Thymiakou E; Laboratory of Biochemistry, University of Crete Medical School, Heraklion 71003, Greece; Gene Regulation and Genomics group, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology of Hellas, Heraklion 70013, Greece.
Othman A; Institute of Clinical Chemistry, University of Zurich and University Hospital of Zurich, Zurich, Switzerland.
Hornemann T; Institute of Clinical Chemistry, University of Zurich and University Hospital of Zurich, Zurich, Switzerland.
Kardassis D; Laboratory of Biochemistry, University of Crete Medical School, Heraklion 71003, Greece; Gene Regulation and Genomics group, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology of Hellas, Heraklion 70013, Greece. Electronic address: .
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Źródło :
Metabolism: clinical and experimental [Metabolism] 2020 Sep; Vol. 110, pp. 154307. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hepatocyte Nuclear Factor 4/*physiology
Lipoproteins, HDL/*metabolism
Non-alcoholic Fatty Liver Disease/*etiology
ATP Binding Cassette Transporter 1/physiology ; Animals ; Aryldialkylphosphatase/metabolism ; Gene Expression Profiling ; Lipid Metabolism ; Lipoproteins, HDL/chemistry ; Lysophospholipids/blood ; Mice ; Mice, Knockout ; Non-alcoholic Fatty Liver Disease/metabolism ; Sphingosine/analogs & derivatives ; Sphingosine/blood
Czasopismo naukowe
Tytuł :
Liraglutide improves lipid metabolism by enhancing cholesterol efflux associated with ABCA1 and ERK1/2 pathway.
Autorzy :
Wu YR; Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Disease, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Shi XY; Division of Endocrinology, Beijing Chaoyang Integrative Medicine Emergency Medical Center, Beijing, 100022, China.
Ma CY; Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Disease, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Zhang Y; Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Disease, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Xu RX; Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Disease, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China. .
Li JJ; Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Disease, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China. .
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Źródło :
Cardiovascular diabetology [Cardiovasc Diabetol] 2019 Nov 09; Vol. 18 (1), pp. 146. Date of Electronic Publication: 2019 Nov 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP Binding Cassette Transporter 1/*metabolism
Cholesterol/*blood
Diabetes Mellitus/*drug therapy
Extracellular Signal-Regulated MAP Kinases/*metabolism
Hepatocytes/*drug effects
Hypoglycemic Agents/*pharmacology
Incretins/*pharmacology
Liraglutide/*pharmacology
Liver/*drug effects
ATP Binding Cassette Transporter 1/genetics ; Animals ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Diabetes Mellitus/blood ; Diabetes Mellitus/enzymology ; Diet, High-Fat ; Disease Models, Animal ; Hep G2 Cells ; Hepatocytes/enzymology ; Humans ; Liver/enzymology ; Male ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Phosphorylation ; Signal Transduction
Czasopismo naukowe
Tytuł :
Expression of LXR‑β, ABCA1 and ABCG1 in human triple‑negative breast cancer tissues.
Autorzy :
Pan H; Department of Medical Oncology, Taizhou Integrated Chinese and Western Medicine Hospital, Zhejiang University of Traditional Chinese Medicine, Wenling, Zhejiang 317500, P.R. China.
Zheng Y; Department of Radiology, Traditional Chinese Medical Hospital of Wenling, Wenling, Zhejiang 317500, P.R. China.
Pan Q; Department of Thoracosurgery, Traditional Chinese Medical Hospital of Wenling, Wenling, Zhejiang 317500, P.R. China.
Chen H; Department of Pathology, School of Basic Medical Science, Wuhan University, Wuhan, Hubei 430071, P.R. China.
Chen F; Department of Thoracosurgery, Traditional Chinese Medical Hospital of Wenling, Wenling, Zhejiang 317500, P.R. China.
Wu J; Department of Pathology, School of Basic Medical Science, Wuhan University, Wuhan, Hubei 430071, P.R. China.
Di D; Department of Pathology, School of Basic Medical Science, Wuhan University, Wuhan, Hubei 430071, P.R. China.
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Źródło :
Oncology reports [Oncol Rep] 2019 Nov; Vol. 42 (5), pp. 1869-1877. Date of Electronic Publication: 2019 Aug 14.
Typ publikacji :
Journal Article
MeSH Terms :
ATP Binding Cassette Transporter 1/*metabolism
ATP Binding Cassette Transporter, Subfamily G, Member 1/*metabolism
Liver X Receptors/*metabolism
Triple Negative Breast Neoplasms/*pathology
ATP Binding Cassette Transporter 1/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 1/genetics ; Adult ; Aged ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Case-Control Studies ; Gene Expression Regulation, Neoplastic ; Humans ; Liver X Receptors/genetics ; Middle Aged ; Neoplasm Grading ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
LXRβ controls glioblastoma cell growth, lipid balance, and immune modulation independently of ABCA1.
Autorzy :
Patel D; Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Ahmad F; Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Kambach DM; Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Sun Q; Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Halim AS; Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Kramp T; Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Camphausen KA; Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Stommel JM; Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. .
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Źródło :
Scientific reports [Sci Rep] 2019 Oct 29; Vol. 9 (1), pp. 15458. Date of Electronic Publication: 2019 Oct 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Lipid Metabolism*
ATP Binding Cassette Transporter 1/*physiology
Brain Neoplasms/*pathology
Cell Proliferation/*physiology
Glioblastoma/*pathology
Liver X Receptors/*physiology
ATP Binding Cassette Transporter 1/genetics ; Brain Neoplasms/immunology ; Brain Neoplasms/metabolism ; Cholesterol/metabolism ; Glioblastoma/immunology ; Glioblastoma/metabolism ; Homeostasis ; Humans ; Liver X Receptors/metabolism ; Mevalonic Acid/metabolism ; Signal Transduction ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
The phosphatase activity of soluble epoxide hydrolase regulates ATP-binding cassette transporter-A1-dependent cholesterol efflux.
Autorzy :
Lien CC; Graduate Institute and Department of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chen CH; Department of Physiology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Lee YM; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; Graduate Institute of Life Science, National Defense Medical Center, Taipei, Taiwan.
Guo BC; Graduate Institute and Department of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Cheng LC; Division of Basic Medical Sciences, Department of Nursing, Chang Gung University of Science and Technology, Taoyuan, Taiwan.
Pan CC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Shyue SK; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Lee TS; Graduate Institute and Department of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Oct; Vol. 23 (10), pp. 6611-6621. Date of Electronic Publication: 2019 Aug 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP Binding Cassette Transporter 1/*genetics
Atherosclerosis/*enzymology
Cholesterol/*metabolism
Epoxide Hydrolases/*genetics
Epoxide Hydrolases/*metabolism
Foam Cells/*enzymology
Macrophages/*enzymology
Phosphoprotein Phosphatases/*metabolism
ATP Binding Cassette Transporter 1/metabolism ; Animals ; Apolipoproteins E/deficiency ; Atherosclerosis/genetics ; Atherosclerosis/metabolism ; Epoxide Hydrolases/antagonists & inhibitors ; Foam Cells/metabolism ; Lipid Metabolism ; Lipoproteins, LDL/metabolism ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL ; Phosphorylation ; Protein Binding
Czasopismo naukowe
Tytuł :
Elevated Lipoprotein(a) Levels Lower ABCA1 Cholesterol Efflux Capacity.
Autorzy :
Tavori H; Department of Medicine, Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, Oregon.
Fenton AM; Department of Medicine, Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, Oregon.
Plubell DL; Department of Medicine, Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, Oregon.
Rosario S; Department of Medicine, Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, Oregon.
Yerkes E; Department of Medicine, Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, Oregon.
Gasik R; Department of Medicine, Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, Oregon.
Miles J; Department of Medicine, Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, Oregon.
Bergstrom P; Department of Medicine, Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, Oregon.
Minnier J; Department of Medicine, Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, Oregon.
Fazio S; Department of Medicine, Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, Oregon.
Pamir N; Department of Medicine, Knight Cardiovascular Institute, Oregon Health & Sciences University, Portland, Oregon.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2019 Oct 01; Vol. 104 (10), pp. 4793-4803.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP Binding Cassette Transporter 1/*physiology
Cholesterol/*metabolism
Lipoprotein(a)/*blood
Lipoprotein(a)/*pharmacology
ATP Binding Cassette Transporter 1/metabolism ; Adult ; Animals ; Biological Transport/drug effects ; Cells, Cultured ; Cricetinae ; Female ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Humans ; Macrophages/drug effects ; Macrophages/metabolism ; Male ; Mice ; Middle Aged
Czasopismo naukowe

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