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Tytuł:
The association between impairment of HDL cholesterol efflux capacity and atrial remodeling in atrial fibrillation.
Autorzy:
Minami-Takano A; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.; Department of Clinical Engineering, Juntendo University Hospital, Hongo 2-1-1, Bunkyo, Tokyo, 113-0033, Japan.
Iwata H; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan. .
Miyosawa K; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.; Tokyo New Drug Research Laboratories, Kowa Company, Ltd, Tokyo, Japan.
Shiozawa T; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hayashi H; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Funamizu T; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Ishii K; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Nozaki Y; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tabuchi H; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Sekita G; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Shimada K; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Sumiyoshi M; Department of Cardiovascular Medicine, Juntendo University Nerima Hospital, Tokyo, Japan.
Nakazato Y; Department of Cardiovascular Medicine, Juntendo University Urayasu Hospital, Chiba, Japan.
Daida H; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Minamino T; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.; Japan Agency for Medical Research and Development-Core Research for Evolutionary Medical Science and Technology (AMED-CREST), Japan Agency for Medical Research and Development, Tokyo, Japan.
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Źródło:
Scientific reports [Sci Rep] 2021 Feb 11; Vol. 11 (1), pp. 3547. Date of Electronic Publication: 2021 Feb 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP Binding Cassette Transporter 1/*genetics
Atrial Fibrillation/*genetics
Atrial Remodeling/*genetics
Cholesterol, HDL/*blood
ATP Binding Cassette Transporter 1/blood ; Aged ; Atrial Fibrillation/blood ; Atrial Fibrillation/pathology ; Cholesterol/blood ; Cross-Sectional Studies ; Cyclic AMP/blood ; Female ; Heart Atria/metabolism ; Heart Atria/pathology ; Humans ; Lipoproteins, HDL/blood ; Male ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The PPAR pan-agonist tetradecylthioacetic acid promotes redistribution of plasma cholesterol towards large HDL.
Autorzy:
Lundåsen T; Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
Pedrelli M; Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.; Translational Science and Experimental Medicine, Research and Early Development, Cardiovascular Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Bjørndal B; Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Sports, Physical activity and Food, Faculty of Education, Arts and Sports, Western Norway University of Applied Sciences, Bergen, Norway.
Rozell B; Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
Kuiper RV; Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
Burri L; Department of Clinical Science, University of Bergen, Bergen, Norway.
Pavanello C; Dipartimento di Scienze Farmacologiche e Biomolecolari, Centro Enrica Grossi Paoletti, Università degli Studi di Milano, Milan, Italy.
Turri M; Dipartimento di Scienze Farmacologiche e Biomolecolari, Centro Enrica Grossi Paoletti, Università degli Studi di Milano, Milan, Italy.
Skorve J; Department of Clinical Science, University of Bergen, Bergen, Norway.
Berge RK; Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Alexson SEH; Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
Tillander V; Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
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Źródło:
PloS one [PLoS One] 2020 Mar 16; Vol. 15 (3), pp. e0229322. Date of Electronic Publication: 2020 Mar 16 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholesterol, HDL/*blood
Diet, High-Fat/*adverse effects
Lipoproteins/*metabolism
PPAR alpha/*agonists
Sulfides/*administration & dosage
ATP Binding Cassette Transporter 1/genetics ; ATP Binding Cassette Transporter 1/metabolism ; Animals ; Body Weight/drug effects ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/metabolism ; Lipid Metabolism/drug effects ; Liver/drug effects ; Liver/metabolism ; Male ; Mice ; Stearoyl-CoA Desaturase/genetics ; Stearoyl-CoA Desaturase/metabolism ; Sulfides/pharmacology ; Triglycerides/blood
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency.
Autorzy:
Macpherson ME; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway. .; Section of Clinical Immunology and Infectious Diseases, Department of Rheumatology, Dermatology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway. .; Institute of Clinical Medicine, University of Oslo, Oslo, Norway. .
Halvorsen B; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Yndestad A; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Ueland T; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Faculty of Health Sciences and K.G. Jebsen TREC, University of Tromsø, Tromsø, Norway.
Mollnes TE; Department of Immunology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Laboratory, Nordland Hospital, Bodø, Norway.; Faculty of Health Sciences and K.G. Jebsen TREC, University of Tromsø, Tromsø, Norway.; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway.
Berge RK; Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Rashidi A; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Otterdal K; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Gregersen I; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Kong XY; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Holven KB; Department of Nutrition, Institute for Basic Medical Sciences, University of Oslo, Oslo, Norway.; Norwegian National Advisory Unit on Familial Hypercholesterolemia, Oslo University Hospital Rikshospitalet, Oslo, Norway.
Aukrust P; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Department of Rheumatology, Dermatology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Faculty of Health Sciences and K.G. Jebsen TREC, University of Tromsø, Tromsø, Norway.
Fevang B; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Department of Rheumatology, Dermatology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Jørgensen SF; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Department of Rheumatology, Dermatology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
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Źródło:
Scientific reports [Sci Rep] 2019 Jul 01; Vol. 9 (1), pp. 9427. Date of Electronic Publication: 2019 Jul 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholesterol, HDL/*metabolism
Common Variable Immunodeficiency/*pathology
Inflammation/*pathology
ATP Binding Cassette Transporter 1/genetics ; ATP Binding Cassette Transporter 1/metabolism ; Activating Transcription Factor 3/genetics ; Activating Transcription Factor 3/metabolism ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Apolipoprotein A-I/blood ; Autoimmune Diseases/complications ; C-Reactive Protein/analysis ; Case-Control Studies ; Cholesterol, HDL/blood ; Common Variable Immunodeficiency/complications ; Down-Regulation ; Female ; Humans ; Inflammation/immunology ; Interleukin-2 Receptor alpha Subunit/analysis ; Leukocytes, Mononuclear/cytology ; Leukocytes, Mononuclear/metabolism ; Macrophages/cytology ; Macrophages/metabolism ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Allele-specific enhancers mediate associations between LCAT and ABCA1 polymorphisms and HDL metabolism.
Autorzy:
Howard AD; Division of Endocrinology, Nutrition, and Diabetes, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Wang X; Division of Endocrinology, Nutrition, and Diabetes, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Prasad M; Division of Endocrinology, Nutrition, and Diabetes, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Sahu AD; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America.
Aniba R; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America.
Miller M; Center for Preventive Cardiology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States of America.
Hannenhalli S; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America.
Chang YC; Division of Endocrinology, Nutrition, and Diabetes, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
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Źródło:
PloS one [PLoS One] 2019 Apr 30; Vol. 14 (4), pp. e0215911. Date of Electronic Publication: 2019 Apr 30 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Alleles*
Enhancer Elements, Genetic*
ATP Binding Cassette Transporter 1/*genetics
Cholesterol, HDL/*metabolism
Phosphatidylcholine-Sterol O-Acyltransferase/*genetics
Base Sequence ; Cell Line ; Chromatin/metabolism ; Genome-Wide Association Study ; Humans ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Liver/metabolism ; Polymorphism, Single Nucleotide/genetics ; Promoter Regions, Genetic ; Protein Binding ; Response Elements/genetics ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages.
Autorzy:
Ruuth M; Wihuri Research Institute, FI-00290, Helsinki, Finland.; Research Program Unit, University of Helsinki, FI-00014, Helsinki, Finland.
Soronen J; Genomics and Biomarkers Unit, National Institute for Health and Welfare, FI-00251, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Tukholmankatu 8, 00290, Helsinki, Finland.
Kaiharju E; Genomics and Biomarkers Unit, National Institute for Health and Welfare, FI-00251, Helsinki, Finland.
Merikanto K; Genomics and Biomarkers Unit, National Institute for Health and Welfare, FI-00251, Helsinki, Finland.
Perttilä J; Minerva Foundation Institute for Medical Research, Tukholmankatu 8, 00290, Helsinki, Finland.
Metso J; Genomics and Biomarkers Unit, National Institute for Health and Welfare, FI-00251, Helsinki, Finland.
Lee-Rueckert M; Wihuri Research Institute, FI-00290, Helsinki, Finland.
Taskinen MR; Diabetes and Obesity Research Program, University of Helsinki, FI-00014, Helsinki, Finland.
Kovanen PT; Wihuri Research Institute, FI-00290, Helsinki, Finland.
Öörni K; Wihuri Research Institute, FI-00290, Helsinki, Finland.
Olkkonen VM; Minerva Foundation Institute for Medical Research, Tukholmankatu 8, 00290, Helsinki, Finland.; Department of Anatomy, Faculty of Medicine, University of Helsinki, FI-00014, Helsinki, Finland.
Jauhiainen MS; Genomics and Biomarkers Unit, National Institute for Health and Welfare, FI-00251, Helsinki, Finland. .; Minerva Foundation Institute for Medical Research, Tukholmankatu 8, 00290, Helsinki, Finland. .
Laurila PP; Genomics and Biomarkers Unit, National Institute for Health and Welfare, FI-00251, Helsinki, Finland.; Department of Medical and Clinical Genetics, University of Helsinki, FI-00014, Helsinki, Finland.; Institute for Molecular Medicine Finland, FIMM, FI-00251, Helsinki, Finland.
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Źródło:
Lipids in health and disease [Lipids Health Dis] 2018 Dec 13; Vol. 17 (1), pp. 285. Date of Electronic Publication: 2018 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Cholesterol/*genetics
Cholesterol, HDL/*genetics
Lipoproteins, HDL/*genetics
Upstream Stimulatory Factors/*genetics
ATP Binding Cassette Transporter 1/genetics ; Animals ; Chemokine CCL2/genetics ; Cholesterol/blood ; Gene Expression/genetics ; Humans ; Inflammation/blood ; Inflammation/genetics ; Inflammation/pathology ; Insulin Resistance/genetics ; Lipoproteins, HDL/blood ; Macrophages, Peritoneal/metabolism ; Macrophages, Peritoneal/pathology ; Male ; Mice ; Mice, Knockout ; Obesity/blood ; Obesity/genetics ; Obesity/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels.
Autorzy:
Goedeke L; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, USA.; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Medicine, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York, USA.; Department of Cell Biology, New York University School of Medicine, New York, New York, USA.
Rotllan N; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, USA.; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Canfrán-Duque A; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, USA.; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Aranda JF; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, USA.; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Medicine, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York, USA.
Ramírez CM; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, USA.; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Araldi E; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, USA.; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Medicine, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York, USA.; Department of Cell Biology, New York University School of Medicine, New York, New York, USA.
Lin CS; Department of Medicine, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York, USA.; Department of Cell Biology, New York University School of Medicine, New York, New York, USA.
Anderson NN; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Wagschal A; Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, USA.; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
de Cabo R; Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.
Horton JD; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Lasunción MA; Servicio de Bioquímica-Investigación, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, Madrid, Spain.; Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición, Madrid, Spain.
Näär AM; Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, USA.; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
Suárez Y; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, USA.; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Medicine, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York, USA.; Department of Cell Biology, New York University School of Medicine, New York, New York, USA.
Fernández-Hernando C; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, USA.; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Medicine, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York, USA.; Department of Cell Biology, New York University School of Medicine, New York, New York, USA.
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Źródło:
Nature medicine [Nat Med] 2015 Nov; Vol. 21 (11), pp. 1280-9. Date of Electronic Publication: 2015 Oct 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP Binding Cassette Transporter 1/*genetics
Cholesterol, HDL/*metabolism
Cholesterol, LDL/*metabolism
Hepatocytes/*metabolism
Liver/*metabolism
MicroRNAs/*genetics
Receptors, LDL/*genetics
ATP Binding Cassette Transporter 1/metabolism ; Animals ; Gene Expression Regulation ; Hep G2 Cells ; High-Throughput Screening Assays ; Humans ; Mice ; MicroRNAs/metabolism ; RNA Processing, Post-Transcriptional ; Receptors, LDL/metabolism ; Signal Transduction ; Sterol Regulatory Element Binding Protein 1/genetics ; Sterol Regulatory Element Binding Protein 1/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Human paraoxonase 1 overexpression in mice stimulates HDL cholesterol efflux and reverse cholesterol transport.
Autorzy:
Ikhlef S; Research Centre on Aging, Sherbrooke, Quebec, Canada.
Berrougui H; Research Centre on Aging, Sherbrooke, Quebec, Canada.; Department of Biology, Polydisciplinary Faculty, University Sultan Moulay Slimane, Beni Mellal, Morocco.
Kamtchueng Simo O; Research Centre on Aging, Sherbrooke, Quebec, Canada.
Zerif E; Department of Pediatric, Immunology Division, Centre de Recherche Clinique CHUS, University of Sherbrooke, Sherbrooke, Quebec, Canada.
Khalil A; Research Centre on Aging, Sherbrooke, Quebec, Canada.; Department of Medicine, Geriatrics Service, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada.
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Źródło:
PloS one [PLoS One] 2017 Mar 09; Vol. 12 (3), pp. e0173385. Date of Electronic Publication: 2017 Mar 09 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Aryldialkylphosphatase/*genetics
Cholesterol, HDL/*metabolism
ATP Binding Cassette Transporter 1/metabolism ; Animals ; Aryldialkylphosphatase/blood ; Biological Transport ; Cell Line ; Gene Expression ; Homeostasis ; Humans ; Liver X Receptors/metabolism ; Macrophages, Peritoneal/cytology ; Macrophages, Peritoneal/metabolism ; Male ; Mice ; PPAR gamma/metabolism ; Signal Transduction ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effects of n-3 polyunsaturated fatty acids high fat diet intervention on the synthesis of hepatic high-density lipoprotein cholesterol in obesity-insulin resistance rats.
Autorzy:
Xie X; Laboratory Animal Center of the Academy of Military Medical Sciences, Beijing, 100071, China.
Zhang T; Laboratory Animal Center of the Academy of Military Medical Sciences, Beijing, 100071, China.
Zhao S; Laboratory Animal Center of the Academy of Military Medical Sciences, Beijing, 100071, China.
Li W; Laboratory Animal Center of the Academy of Military Medical Sciences, Beijing, 100071, China.
Ma L; Laboratory Animal Center of the Academy of Military Medical Sciences, Beijing, 100071, China.
Ding M; Laboratory Animal Center of the Academy of Military Medical Sciences, Beijing, 100071, China.
Liu Y; Laboratory Animal Center of the Academy of Military Medical Sciences, Beijing, 100071, China. Bj_.
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Źródło:
Lipids in health and disease [Lipids Health Dis] 2016 Apr 22; Vol. 15, pp. 81. Date of Electronic Publication: 2016 Apr 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin Resistance*
Cholesterol, HDL/*biosynthesis
Fatty Acids, Omega-3/*pharmacology
Obesity/*diet therapy
ATP Binding Cassette Transporter 1/genetics ; Animals ; Apolipoprotein A-I/blood ; Apolipoprotein A-I/genetics ; Apolipoprotein A-I/metabolism ; Body Weight/drug effects ; Fish Oils/pharmacology ; Gene Expression Regulation/drug effects ; Lipids/blood ; Liver/drug effects ; Liver/metabolism ; Male ; Obesity/metabolism ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis.
Autorzy:
Wagschal A; Massachusetts General Hospital Center for Cancer Research, Charlestown, Massachusetts, USA.; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
Najafi-Shoushtari SH; Massachusetts General Hospital Center for Cancer Research, Charlestown, Massachusetts, USA.; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
Wang L; Massachusetts General Hospital Center for Cancer Research, Charlestown, Massachusetts, USA.; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
Goedeke L; Section of Comparative Medicine, Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA.
Sinha S; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
deLemos AS; Liver Center and Gastrointestinal Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Black JC; Massachusetts General Hospital Center for Cancer Research, Charlestown, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.
Ramírez CM; Section of Comparative Medicine, Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA.
Li Y; Department of Medicine, Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Tewhey R; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.
Hatoum I; Obesity, Metabolism and Nutrition Institute and Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Shah N; Systems Genomics and Bioinformatics Unit, Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Lu Y; Systems Genomics and Bioinformatics Unit, Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Kristo F; Massachusetts General Hospital Center for Cancer Research, Charlestown, Massachusetts, USA.
Psychogios N; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Vrbanac V; Harvard University Center for AIDS Research, Cambridge, Massachusetts USA.
Lu YC; Center for Vascular Biology, Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, Cornell University, New York, New York, USA.
Hla T; Center for Vascular Biology, Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, Cornell University, New York, New York, USA.
de Cabo R; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.
Tsang JS; Systems Genomics and Bioinformatics Unit, Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Schadt E; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Sabeti PC; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.
Kathiresan S; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.
Cohen DE; Department of Medicine, Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Whetstine J; Massachusetts General Hospital Center for Cancer Research, Charlestown, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.
Chung RT; Liver Center and Gastrointestinal Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.
Fernández-Hernando C; Section of Comparative Medicine, Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA.
Kaplan LM; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.; Obesity, Metabolism and Nutrition Institute and Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Bernards A; Massachusetts General Hospital Center for Cancer Research, Charlestown, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.
Gerszten RE; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.
Näär AM; Massachusetts General Hospital Center for Cancer Research, Charlestown, Massachusetts, USA.; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
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Źródło:
Nature medicine [Nat Med] 2015 Nov; Vol. 21 (11), pp. 1290-7. Date of Electronic Publication: 2015 Oct 26.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Diet, High-Fat*
ATP Binding Cassette Transporter 1/*metabolism
Cholesterol, HDL/*metabolism
Cholesterol, LDL/*metabolism
Dyslipidemias/*genetics
MicroRNAs/*genetics
Receptors, LDL/*metabolism
Triglycerides/*metabolism
Animals ; Apolipoproteins E/genetics ; Cholesterol/metabolism ; Genome-Wide Association Study ; Homeostasis/genetics ; Humans ; Lipoproteins/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Adrenal Function in females with low plasma HDL-C due to mutations in ABCA1 and LCAT.
Autorzy:
Bochem AE; Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Holleboom AG; Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Romijn JA; Department of Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Hoekstra M; Leiden/Amsterdam Center for Drug Research, Leiden, The Netherlands.
Dallinga GM; Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands; Department of Experimental Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Motazacker MM; Department of Experimental Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Hovingh GK; Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Kuivenhoven JA; Department of Pathology & Medical Biology, Medical Biology Section, Molecular Genetics, University Medical Center Groningen, University of Groningen, The Netherlands.
Stroes ES; Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
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Źródło:
PloS one [PLoS One] 2014 May 19; Vol. 9 (5), pp. e90967. Date of Electronic Publication: 2014 May 19 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP Binding Cassette Transporter 1/*genetics
Adrenal Glands/*metabolism
Cholesterol, HDL/*metabolism
Phosphatidylcholine-Sterol O-Acyltransferase/*metabolism
17-Ketosteroids/metabolism ; Adult ; Female ; Humans ; Middle Aged ; Mutation/genetics ; Phosphatidylcholine-Sterol O-Acyltransferase/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype.
Autorzy:
Holven KB; Department of Nutrition, Institute for Basic Medical Sciences, University of Oslo, Oslo, Norway ; Faculty of Medicine, University of Oslo, Oslo, Norway.
Retterstøl K
Ueland T
Ulven SM
Nenseter MS
Sandvik M
Narverud I
Berge KE
Ose L
Aukrust P
Halvorsen B
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Źródło:
PloS one [PLoS One] 2013 Nov 11; Vol. 8 (11), pp. e78241. Date of Electronic Publication: 2013 Nov 11 (Print Publication: 2013).
Typ publikacji:
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Phenotype*
Cholesterol, HDL/*blood
ATP Binding Cassette Transporter 1/blood ; ATP Binding Cassette Transporter, Subfamily G, Member 1 ; ATP-Binding Cassette Transporters/blood ; Adult ; Aged ; Atherosclerosis/blood ; Biological Transport, Active ; C-Reactive Protein/metabolism ; Chemokine CXCL16 ; Chemokines, CXC/blood ; Female ; Humans ; Inflammation/blood ; Intercellular Adhesion Molecule-1/blood ; Lipoproteins, LDL/blood ; Male ; Matrix Metalloproteinase 9/blood ; Middle Aged ; Neopterin/blood ; Oxidation-Reduction ; Receptors, Scavenger/blood
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Reduced biliary sterol output with no change in total faecal excretion in mice expressing a human apolipoprotein A-I variant.
Autorzy:
Parolini C; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milan, Italy.
Caligari S
Gilio D
Manzini S
Busnelli M
Montagnani M
Locatelli M
Diani E
Giavarini F
Caruso D
Roda E
Roda A
Sirtori CR
Chiesa G
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Źródło:
Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2012 Oct; Vol. 32 (9), pp. 1363-71. Date of Electronic Publication: 2012 Jul 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apolipoprotein A-I/*genetics
Bile/*metabolism
Cholesterol, HDL/*metabolism
ATP Binding Cassette Transporter 1 ; ATP-Binding Cassette Transporters/metabolism ; Animals ; Apolipoprotein A-I/metabolism ; Bile/chemistry ; Cholesterol, HDL/analysis ; Disease Models, Animal ; Feces/chemistry ; Gastrointestinal Contents/chemistry ; Gene Expression Profiling ; Humans ; Liver/chemistry ; Male ; Mice ; Models, Animal ; Scavenger Receptors, Class B/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
High hydrostatic pressure extract of garlic increases the HDL cholesterol level via up-regulation of apolipoprotein A-I gene expression in rats fed a high-fat diet.
Autorzy:
Lee S; Department of Nutritional Science and Food Management, Ewha Womans University, Seoul, Republic of Korea.
Joo H
Kim CT
Kim IH
Kim Y
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Źródło:
Lipids in health and disease [Lipids Health Dis] 2012 Jun 19; Vol. 11, pp. 77. Date of Electronic Publication: 2012 Jun 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Garlic*
Apolipoprotein A-I/*genetics
Cholesterol, HDL/*blood
Diet, High-Fat/*adverse effects
ATP Binding Cassette Transporter 1 ; ATP-Binding Cassette Transporters/genetics ; Animals ; Base Sequence ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/diet therapy ; Cardiovascular Diseases/genetics ; Cardiovascular Diseases/metabolism ; Disease Models, Animal ; Hydrostatic Pressure ; Lipids/blood ; Liver/drug effects ; Liver/metabolism ; Male ; Phosphatidylcholine-Sterol O-Acyltransferase/genetics ; Plant Extracts/administration & dosage ; Plant Extracts/isolation & purification ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley ; Up-Regulation/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Segregation of LIPG, CETP, and GALNT2 mutations in Caucasian families with extremely high HDL cholesterol.
Autorzy:
Tietjen I; Xenon Pharmaceuticals Inc., Burnaby, Canada.
Hovingh GK
Singaraja RR
Radomski C
Barhdadi A
McEwen J
Chan E
Mattice M
Legendre A
Franchini PL
Dubé MP
Kastelein JJ
Hayden MR
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (8), pp. e37437. Date of Electronic Publication: 2012 Aug 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mutation*
Cholesterol Ester Transfer Proteins/*genetics
Cholesterol, HDL/*genetics
Hypercholesterolemia/*genetics
Lipase/*genetics
N-Acetylgalactosaminyltransferases/*genetics
ATP Binding Cassette Transporter 1 ; ATP-Binding Cassette Transporters/genetics ; Aged ; Alternative Splicing ; Cohort Studies ; Coronary Artery Disease/genetics ; Family Health ; Female ; Humans ; Male ; Middle Aged ; Phenotype ; Sequence Analysis, DNA ; White People ; Polypeptide N-acetylgalactosaminyltransferase
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Retroendocytosis pathway of ABCA1/apoA-I contributes to HDL formation.
Autorzy:
Azuma Y; Kyoto University, Japan.
Takada M
Shin HW
Kioka N
Nakayama K
Ueda K
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Źródło:
Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 2009 Feb; Vol. 14 (2), pp. 191-204. Date of Electronic Publication: 2008 Jan 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP-Binding Cassette Transporters/*metabolism
Apolipoprotein A-I/*metabolism
Cholesterol, HDL/*metabolism
Endocytosis/*physiology
ATP Binding Cassette Transporter 1 ; ATP-Binding Cassette Transporters/physiology ; Animals ; CHO Cells ; Cells, Cultured ; Clathrin/physiology ; Cricetinae ; Cricetulus ; HeLa Cells ; Humans ; Models, Biological ; Signal Transduction/physiology ; Tissue Distribution
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Multiple splice defects in ABCA1 cause low HDL-C in a family with hypoalphalipoproteinemia and premature coronary disease.
Autorzy:
Rhyne J; Department of Medicine, Cardiology Division, University Maryland Medical Center and Baltimore Veterans Affairs Medical Center, 22 South Greene Street, Baltimore, MD 21201, USA. />Mantaring MM
Gardner DF
Miller M
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Źródło:
BMC medical genetics [BMC Med Genet] 2009 Jan 08; Vol. 10, pp. 1. Date of Electronic Publication: 2009 Jan 08.
Typ publikacji:
Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Mutation*
ATP-Binding Cassette Transporters/*genetics
Cholesterol, HDL/*blood
Coronary Disease/*genetics
Hypoalphalipoproteinemias/*genetics
ATP Binding Cassette Transporter 1 ; Adult ; Alternative Splicing ; Cholesterol, HDL/genetics ; Coronary Disease/blood ; Coronary Disease/complications ; DNA Mutational Analysis ; DNA Primers ; Female ; Humans ; Hypoalphalipoproteinemias/blood ; Hypoalphalipoproteinemias/complications ; Male ; Pedigree ; Polymerase Chain Reaction ; Polymorphism, Single-Stranded Conformational
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Multiple rare alleles contribute to low plasma levels of HDL cholesterol.
Autorzy:
Cohen JC; Donald W. Reynolds Cardiovascular Clinical Research Center and McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. />Kiss RS
Pertsemlidis A
Marcel YL
McPherson R
Hobbs HH
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Źródło:
Science (New York, N.Y.) [Science] 2004 Aug 06; Vol. 305 (5685), pp. 869-72.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Alleles*
Genetic Variation*
ATP-Binding Cassette Transporters/*genetics
Apolipoprotein A-I/*genetics
Cholesterol, HDL/*blood
Phosphatidylcholine-Sterol O-Acyltransferase/*genetics
ATP Binding Cassette Transporter 1 ; ATP-Binding Cassette Transporters/chemistry ; ATP-Binding Cassette Transporters/metabolism ; Adult ; Aged ; Amino Acid Substitution ; Apolipoprotein A-I/chemistry ; Apolipoprotein A-I/metabolism ; Black People/genetics ; Female ; Haplotypes ; Humans ; Male ; Middle Aged ; Phosphatidylcholine-Sterol O-Acyltransferase/chemistry ; Phosphatidylcholine-Sterol O-Acyltransferase/metabolism ; Quantitative Trait, Heritable ; White People/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A promoter variant of the ATP-binding cassette transporter A1 gene alters the HDL cholesterol level in the general Japanese population.
Autorzy:
Shioji K; Department of Epidemiology, Research Institute, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Nishioka J; Department of Epidemiology, Research Institute, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Naraba H; Department of Epidemiology, Research Institute, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Kokubo Y; Department of Preventive Cardiology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Mannami T; Department of Preventive Cardiology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Inamoto N; Department of Preventive Cardiology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Kamide K; Division of Hypertension and Nephrology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Takiuchi S; Division of Hypertension and Nephrology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Yoshii M; Division of Hypertension and Nephrology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Miwa Y; Division of Hypertension and Nephrology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Kawano Y; Division of Hypertension and Nephrology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Miyata T; Department of Preventive Cardiology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Miyazaki S; Division of Cardiology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Goto Y; Division of Cardiology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Nonogi H; Division of Cardiology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Tago N; Department of Epidemiology, Research Institute, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Iwai N; Department of Epidemiology, Research Institute, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan. .
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Źródło:
Journal of human genetics [J Hum Genet] 2004; Vol. 49 (3), pp. 141-147. Date of Electronic Publication: 2004 Feb 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Variation*
Promoter Regions, Genetic*
ATP-Binding Cassette Transporters/*genetics
Cholesterol, HDL/*blood
ATP Binding Cassette Transporter 1 ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Base Sequence ; DNA/chemistry ; Exons ; Female ; Genotype ; Humans ; Hypertension/genetics ; Japan ; Linkage Disequilibrium ; Male ; Middle Aged ; Models, Genetic ; Molecular Sequence Data ; Myocardial Infarction/genetics ; Polymorphism, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 23

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