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    Wyświetlanie 1-3 z 3
    Tytuł:
    Comparative Analysis Identifies Similarities between the Human and Murine Microglial Sensomes.
    Autorzy:
    Abels ER; Departments of Neurology and Radiology, Massachusetts General Hospital, NeuroDiscovery Center, Harvard Medical School, Boston, MA 02129, USA.; Department of Neurosurgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
    Nieland L; Departments of Neurology and Radiology, Massachusetts General Hospital, NeuroDiscovery Center, Harvard Medical School, Boston, MA 02129, USA.
    Hickman S; Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.
    Broekman MLD; Department of Neurosurgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.; Department of Neurosurgery, Haaglanden Medical Center, 2597 AX The Hague, The Netherlands.
    El Khoury J; Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.
    Maas SLN; Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.; Department of Pathology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2021 Feb 02; Vol. 22 (3). Date of Electronic Publication: 2021 Feb 02.
    Typ publikacji:
    Comparative Study; Journal Article; Validation Study
    MeSH Terms:
    Microglia/*metabolism
    Receptors, Cell Surface/*genetics
    Aging/genetics ; Aging/metabolism ; Animals ; Cerebral Cortex/metabolism ; Datasets as Topic ; Gene Expression ; Gene Ontology ; Humans ; Inflammation/genetics ; Inflammation/metabolism ; Mice ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Neurodegenerative Diseases/genetics ; Neurodegenerative Diseases/metabolism ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics ; RNA-Seq ; Receptors, Cell Surface/analysis ; Species Specificity
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    GlioM&M: Web-based tool for studying circulating and infiltrating monocytes and macrophages in glioma.
    Autorzy:
    Abels ER; Departments of Neurology and Radiology, Massachusetts General Hospital, and Harvard Medical School, 02129, Boston, Massachusetts, USA.
    Maas SLN; Department of Neurosurgery and Department of Pathology, UMC Utrecht Brain Center, University Medical Center, Utrecht University, Utrecht, 3584 CX, The Netherlands.
    Tai E; Cancer Center, Massachusetts General Hospital, and Harvard Medical School, Boston, 02114, Massachusetts, USA.
    Ting DT; Cancer Center, Massachusetts General Hospital, and Harvard Medical School, Boston, 02114, Massachusetts, USA.
    Broekman MLD; Department of Neurosurgery, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands.; Department of Neurosurgery, Haaglanden Medical Center, The Hague, 2512 VA, The Netherlands.
    Breakefield XO; Departments of Neurology and Radiology, Massachusetts General Hospital, and Harvard Medical School, 02129, Boston, Massachusetts, USA.
    El Khoury J; Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, and Harvard Medical School, Boston, 02129, Massachusetts, USA. .
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    Źródło:
    Scientific reports [Sci Rep] 2020 Jun 18; Vol. 10 (1), pp. 9898. Date of Electronic Publication: 2020 Jun 18.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    User-Computer Interface*
    Brain Neoplasms/*pathology
    Glioma/*pathology
    Macrophages/*cytology
    Monocytes/*cytology
    Animals ; Biomarkers/metabolism ; Brain Neoplasms/immunology ; Cell Line, Tumor ; Cytokines/metabolism ; Databases, Factual ; Disease Models, Animal ; Glioma/immunology ; Lymphocytes, Tumor-Infiltrating/cytology ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Macrophages/immunology ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL ; Monocytes/immunology ; Monocytes/metabolism ; Transplantation, Homologous ; Up-Regulation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Glioblastoma hijacks microglial gene expression to support tumor growth.
    Autorzy:
    Maas SLN; Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.; Department of Neurosurgery, UMC Utrecht Brain Center, University Medical Center, Utrecht University, 3584 CX, Utrecht, The Netherlands.
    Abels ER; Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.
    Van De Haar LL; Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.
    Zhang X; Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.
    Morsett L; Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.
    Sil S; Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.
    Guedes J; Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.; Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517, Coimbra, Portugal.
    Sen P; Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.
    Prabhakar S; Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.
    Hickman SE; Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.
    Lai CP; Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.; Institute of Atomic and Molecular Sciences/Academia Sinica, 10617, Taipei, Taiwan.
    Ting DT; Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.
    Breakefield XO; Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.
    Broekman MLD; Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.; Department of Neurosurgery, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.; Department of Neurosurgery, Haaglanden Medical Center, 2512 VA, The Hague, The Netherlands.
    El Khoury J; Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA. .; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA. .
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    Źródło:
    Journal of neuroinflammation [J Neuroinflammation] 2020 Apr 16; Vol. 17 (1), pp. 120. Date of Electronic Publication: 2020 Apr 16.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gene Expression Regulation, Neoplastic*
    Brain Neoplasms/*metabolism
    Glioblastoma/*metabolism
    Microglia/*metabolism
    Animals ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Extracellular Vesicles/genetics ; Extracellular Vesicles/metabolism ; Extracellular Vesicles/pathology ; Female ; Gene Knock-In Techniques/methods ; Glioblastoma/genetics ; Glioblastoma/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Microglia/pathology ; Tumor Burden/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-3 z 3

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