- Tytuł:
- Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons.
- Autorzy:
- Źródło:
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Acta neuropathologica communications [Acta Neuropathol Commun] 2017 Oct 17; Vol. 5 (1), pp. 74. Date of Electronic Publication: 2017 Oct 17. - Typ publikacji:
- Journal Article
- MeSH Terms:
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Brain/*physiopathology
Neuroglia/*physiology
Neuronal Ceroid-Lipofuscinoses/*physiopathology
Neurons/*physiology
Adult ; Aminopeptidases/deficiency ; Aminopeptidases/genetics ; Animals ; Brain/pathology ; Cell Movement/physiology ; Cell Survival/physiology ; Cells, Cultured ; Child ; Coculture Techniques ; Cytoskeleton/metabolism ; Cytoskeleton/pathology ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/deficiency ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/genetics ; Female ; Glutathione/metabolism ; Humans ; Male ; Membrane Glycoproteins/deficiency ; Membrane Glycoproteins/genetics ; Mice, Inbred C57BL ; Mice, Transgenic ; Molecular Chaperones/genetics ; Neuroglia/pathology ; Neuronal Ceroid-Lipofuscinoses/pathology ; Neurons/pathology ; Serine Proteases/deficiency ; Serine Proteases/genetics ; Tripeptidyl-Peptidase 1 ; Young Adult
Czasopismo naukowe