Comparison between low-level 50 Hz and 900 MHz electromagnetic stimulation on single channel ionic currents and on firing frequency in dorsal root ganglion isolated neurons
Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response.
Autorzy :
Desai R; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. East DA; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. Hardy L; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. Faccenda D; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. Rigon M; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. Crosby J; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. Alvarez MS; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. Singh A; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. Mainenti M; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. Hussey LK; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. Bentham R; Department of Cell and Developmental Biology, Consortium for Mitochondrial Research (CfMR), University College London, Gower Street, London WC1E 6BT, UK. Szabadkai G; Department of Cell and Developmental Biology, Consortium for Mitochondrial Research (CfMR), University College London, Gower Street, London WC1E 6BT, UK.; Department of Biomedical Science, University of Padua, Via Ugo Bassi, 35131 Padua, Italy.; Francis Crick Institute, Midland Road, London NW1 AT, UK. Zappulli V; Department of Comparative Biomedicine and Food Sciences, University of Padua, Viale dell'Universita' 16, 35020 Legnaro (PD), Italy. Dhoot GK; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. Romano LE; William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, UK. Xia D; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. Coppens I; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Baltimore, Baltimore, MD 21205, USA. Hamacher-Brady A; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Baltimore, Baltimore, MD 21205, USA. Chapple JP; William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, UK. AbetiR; Ataxia Centre, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK. Fleck RA; Centre for Ultrastructural Imaging, King's College London, London SE1 1UL, UK. Vizcay-Barrena G; Centre for Ultrastructural Imaging, King's College London, London SE1 1UL, UK. Smith K; Pathobiology and Population Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK. Campanella M; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK. .; Department of Cell and Developmental Biology, Consortium for Mitochondrial Research (CfMR), University College London, Gower Street, London WC1E 6BT, UK.
Pokaż więcej
Źródło :
Science advances [Sci Adv] 2020 Dec 18; Vol. 6 (51). Date of Electronic Publication: 2020 Dec 18 (Print Publication: 2020).
NH-sulfoximine: A novel pharmacological inhibitor of the mitochondrial F 1 F o -ATPase, which suppresses viability of cancerous cells.
Autorzy :
Strobbe D; Department of Biology, University of Rome 'Tor Vergata', Rome, Italy. Pecorari R; Department of Biology, University of Rome 'Tor Vergata', Rome, Italy. Conte O; Department of Biology, University of Rome 'Tor Vergata', Rome, Italy. Minutolo A; Department of Cell and Developmental Biology, Consortium for Mitochondrial Research (CfMR), University College London, London, UK. Hendriks CMM; Institute of Organic Chemistry, RWTH Aachen University, Aachen, Germany. Wiezorek S; Institute of Organic Chemistry, RWTH Aachen University, Aachen, Germany. Faccenda D; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, London, UK. AbetiR; Ataxia Centre, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square London, London, WC1N 3BG, UK. Montesano C; Department of Biology, University of Rome 'Tor Vergata', Rome, Italy. Bolm C; Institute of Organic Chemistry, RWTH Aachen University, Aachen, Germany. Campanella M; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, London, UK.; Department of Cell and Developmental Biology, Consortium for Mitochondrial Research (CfMR), University College London, London, UK.; Department of Biology, University of Rome 'Tor Vergata', Rome, Italy.
Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification.
Autorzy :
Schottlaender LV; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, WC1N3BG London, UK; Dubowitz Neuromuscular Centre, UCL Great Ormond Street Institute of Child Health, WC1N 1EH London, UK; Argentine National Scientific and Technological Research Council (CONICET), C1425FQB Buenos Aires, Argentina; FLENI Neurological Research Institute, C1428 AQK Buenos Aires, Argentina. AbetiR; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, WC1N3BG London, UK. Jaunmuktane Z; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, WC1N3BG London, UK; Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London WC1N 3BG, UK. Macmillan C; Department of Pediatrics, University of Chicago, Chicago, IL 60637, USA. Chelban V; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, WC1N3BG London, UK. O'Callaghan B; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, WC1N3BG London, UK. McKinley J; Department of Neurology, Dublin Neurological Institute at the Mater Misericordiae University Hospital, 57 Eccles St, Dublin 7 DO7W7XF, Ireland; Regional Neurosciences Centre, Royal Victoria Hospital, Belfast BT12 6BA, UK. Maroofian R; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, WC1N3BG London, UK. Efthymiou S; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, WC1N3BG London, UK. Athanasiou-Fragkouli A; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, WC1N3BG London, UK. Forbes R; Neurology Centre, Southern HSC Trust, Craigavon Area Hospital, Portadown BT63 5QQ, UK. Soutar MPM; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK. Livingston JH; Paediatric Neurology, The Leeds Teaching Hospitals NHS Trust, Leeds General Infirmary, Leeds LS1 3EX, UK. Kalmar B; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, WC1N3BG London, UK. Swayne O; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, WC1N3BG London, UK; The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK. Hotton G; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, WC1N3BG London, UK; The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK. Pittman A; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, WC1N3BG London, UK. Mendes de Oliveira JR; Universidade Federal de Pernambuco, Departamento de Neuropsiquiatria, Recife 50670-901, Brazil. de Grandis M; Aix-Marseille University, Inserm, CNRS, Institut Paoli-Calmettes, CRCM, 13009 Marseille, France. Richard-Loendt A; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK. Launchbury F; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK. Althonayan J; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, WC1N3BG London, UK. McDonnell G; Regional Neurosciences Centre, Royal Victoria Hospital, Belfast BT12 6BA, UK. Carr A; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, WC1N3BG London, UK; The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK. Khan S; CENTOGENE AG, Rostock 18055, Germany. Beetz C; CENTOGENE AG, Rostock 18055, Germany. Bisgin A; Medical Genetics Department of Medical Faculty & AGENTEM (Adana Genetic Diseases Diagnosis and Treatment Center), Çukurova University, Adana 01330, Turkey. Tug Bozdogan S; Medical Genetics Department of Medical Faculty & AGENTEM (Adana Genetic Diseases Diagnosis and Treatment Center), Çukurova University, Adana 01330, Turkey. Begtrup A; GeneDx, 207 Perry Parkway, Gaithersburg, MD 20877, USA. Torti E; GeneDx, 207 Perry Parkway, Gaithersburg, MD 20877, USA. Greensmith L; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, WC1N3BG London, UK. Giunti P; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, WC1N3BG London, UK. Morrison PJ; Centre for Cancer Research and Cell Biology, Queens University, Belfast BT9 7AE, UK. Brandner S; Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London WC1N 3BG, UK. Aurrand-Lions M; Aix-Marseille University, Inserm, CNRS, Institut Paoli-Calmettes, CRCM, 13009 Marseille, France. Houlden H; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, WC1N3BG London, UK; The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK; Neurogenetics Laboratory and Clinical Service, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK. Electronic address: .
Pokaż więcej
Corporate Authors :
SYNAPS Study Group; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, WC1N3BG London, UK.
Xeroderma pigmentosum: overview of pharmacology and novel therapeutic strategies for neurological symptoms.
Autorzy :
AbetiR; Ataxia Centre, Department of Clinical and Movement Neurosciences, University College London, Institute of Neurology London, London, UK. Zeitlberger A; Ataxia Centre, Department of Clinical and Movement Neurosciences, University College London, Institute of Neurology London, London, UK. Peelo C; Ataxia Centre, Department of Clinical and Movement Neurosciences, University College London, Institute of Neurology London, London, UK. Fassihi H; National Xeroderma Pigmentosum Service, St John's Institute of Dermatology Guy's and St Thomas' Foundation Trust, London, UK. Sarkany RPE; National Xeroderma Pigmentosum Service, St John's Institute of Dermatology Guy's and St Thomas' Foundation Trust, London, UK. Lehmann AR; Genome Damage and Stability Centre, University of Sussex, Brighton, UK. Giunti P; Ataxia Centre, Department of Clinical and Movement Neurosciences, University College London, Institute of Neurology London, London, UK.; National Xeroderma Pigmentosum Service, St John's Institute of Dermatology Guy's and St Thomas' Foundation Trust, London, UK.
Pokaż więcej
Źródło :
British journal of pharmacology [Br J Pharmacol] 2019 Nov; Vol. 176 (22), pp. 4293-4301. Date of Electronic Publication: 2019 Jan 23.
Complexity of the Genetics and Clinical Presentation of Spinocerebellar Ataxia 17.
Autorzy :
Nethisinghe S; Ataxia Centre, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom. Lim WN; Ataxia Centre, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom. Ging H; Ataxia Centre, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom. Zeitlberger A; Ataxia Centre, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom. AbetiR; Ataxia Centre, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom. Pemble S; Neurogenetics Unit, National Hospital for Neurology and Neurosurgery, London, United Kingdom. Sweeney MG; Neurogenetics Unit, National Hospital for Neurology and Neurosurgery, London, United Kingdom. Labrum R; Neurogenetics Unit, National Hospital for Neurology and Neurosurgery, London, United Kingdom. Cervera C; Neurogenetics Unit, National Hospital for Neurology and Neurosurgery, London, United Kingdom. Houlden H; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, United Kingdom.; MRC Centre for Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, United Kingdom. Rosser E; Department of Clinical Genetics, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom. Limousin P; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Queen Square Institute of Neurology, London, United Kingdom. Kennedy A; Chelsea and Westminster Hospital, London, United Kingdom. Lunn MP; Department of Neuroimmunology, UCL Queen Square Institute of Neurology, London, United Kingdom. Bhatia KP; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Queen Square Institute of Neurology, London, United Kingdom. Wood NW; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom. Hardy J; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom.; The Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, United Kingdom. Polke JM; Neurogenetics Unit, National Hospital for Neurology and Neurosurgery, London, United Kingdom. Veneziano L; Istituto di Farmacologia Traslazionale - National Research Council, Rome, Italy. Brusco A; Department of Medical Sciences, University of Turin, Turin, Italy.; Medical Genetics Unit, Città della Salute e della Scienza University Hospital, Turin, Italy. Davis MB; Ataxia Centre, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom. Giunti P; Ataxia Centre, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom.
Pokaż więcej
Źródło :
Frontiers in cellular neuroscience [Front Cell Neurosci] 2018 Nov 23; Vol. 12, pp. 429. Date of Electronic Publication: 2018 Nov 23 (Print Publication: 2018).
Calcium Deregulation: Novel Insights to Understand Friedreich's Ataxia Pathophysiology.
Autorzy :
AbetiR; Ataxia Centre, Department of Clinical and Movement Neurosciences, Institute of Neurology, University College London, London, United Kingdom. Brown AF; Ataxia Centre, Department of Clinical and Movement Neurosciences, Institute of Neurology, University College London, London, United Kingdom. Maiolino M; Department of Biomedical Sciences and Public Health, School of Medicine, Università Politecnica delle Marche, Ancona, Italy. Patel S; Department of Cell and Developmental Biology, Division of Biosciences, University College London, London, United Kingdom. Giunti P; Ataxia Centre, Department of Clinical and Movement Neurosciences, Institute of Neurology, University College London, London, United Kingdom.
Pokaż więcej
Źródło :
Frontiers in cellular neuroscience [Front Cell Neurosci] 2018 Oct 02; Vol. 12, pp. 264. Date of Electronic Publication: 2018 Oct 02 (Print Publication: 2018).
Novel Nrf2-Inducer Prevents Mitochondrial Defects and Oxidative Stress in Friedreich's Ataxia Models.
Autorzy :
AbetiR; Ataxia Centre, Department of Molecular Neuroscience, UCL Institute of Neurology, London, United Kingdom. Baccaro A; Ataxia Centre, Department of Molecular Neuroscience, UCL Institute of Neurology, London, United Kingdom. Esteras N; Department of Molecular Neuroscience, UCL Institute of Neurology, London, United Kingdom. Giunti P; Ataxia Centre, Department of Molecular Neuroscience, UCL Institute of Neurology, London, United Kingdom.
Pokaż więcej
Źródło :
Frontiers in cellular neuroscience [Front Cell Neurosci] 2018 Jul 17; Vol. 12, pp. 188. Date of Electronic Publication: 2018 Jul 17 (Print Publication: 2018).
mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition.
Autorzy :
Manzoni C; School of Pharmacy, University of Reading, Whiteknights, Reading RG6 6AP, U.K. .; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, U.K. Mamais A; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, U.S.A. Dihanich S; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, U.K. Soutar MPM; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, U.K. Plun-Favreau H; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, U.K. Bandopadhyay R; Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology, 1 Wakefield Street London WC1N 1PJ, U.K. AbetiR; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, U.K.; Department of Molecular Neuroscience, UCL Institute of Neurology, Ataxia Centre, Queen Square, London WC1N 3BG, United Kingdom. Giunti P; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, U.K.; Department of Molecular Neuroscience, UCL Institute of Neurology, Ataxia Centre, Queen Square, London WC1N 3BG, United Kingdom. Hardy J; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, U.K. R Cookson M; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, U.S.A. Tooze SA; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, U.K. Lewis PA; School of Pharmacy, University of Reading, Whiteknights, Reading RG6 6AP, U.K.; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, U.K.
Pokaż więcej
Źródło :
Bioscience reports [Biosci Rep] 2018 Apr 20; Vol. 38 (2). Date of Electronic Publication: 2018 Apr 20 (Print Publication: 2018).
Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons.
Autorzy :
Parviainen L; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology & Neuroscience, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Road, London, SE5 9RX, UK. Dihanich S; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology & Neuroscience, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Road, London, SE5 9RX, UK. Anderson GW; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology & Neuroscience, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Road, London, SE5 9RX, UK. Wong AM; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology & Neuroscience, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Road, London, SE5 9RX, UK. Brooks HR; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology & Neuroscience, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Road, London, SE5 9RX, UK. AbetiR; Department of Molecular Neuroscience, Institute of Neurology, University College London, Queen's Square, London, WC1N, 3BG, UK. Rezaie P; Department of Life, Health and Chemical Sciences, The Open University, Walton Hall, Milton Keynes, MK7 6AA, UK. Lalli G; Wolfson Centre for Age-Related Diseases, King's College London, London, SE1 1UL, UK. Pope S; Genetics and Genomic Medicine UCL Great Ormond Street Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK. Heales SJ; Genetics and Genomic Medicine UCL Great Ormond Street Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK. Mitchison HM; Genetics and Genomic Medicine UCL Great Ormond Street Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK. Williams BP; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology & Neuroscience, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Road, London, SE5 9RX, UK. Cooper JD; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology & Neuroscience, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Road, London, SE5 9RX, UK. .; Department of Pediatrics, Harbor-UCLA Medical Center, Los Angeles Biomedical Research Institute and David Geffen School of Medicine UCLA, 1124 West Carson Street, Hanley Hardison Building, Torrance, CA, 90502, USA. .
A reduction in Drp1-mediated fission compromises mitochondrial health in autosomal recessive spastic ataxia of Charlevoix Saguenay.
Autorzy :
Bradshaw TY; William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, United Kingdom . Romano LE; William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, United Kingdom. Duncan EJ; William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, United Kingdom. Nethisinghe S; William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, United Kingdom. AbetiR; Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, United Kingdom. Michael GJ; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, United Kingdom. Giunti P; Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, United Kingdom. Vermeer S; Department of Clinical Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands. Chapple JP; William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, United Kingdom .
Pokaż więcej
Źródło :
Human molecular genetics [Hum Mol Genet] 2016 Aug 01; Vol. 25 (15), pp. 3232-3244. Date of Electronic Publication: 2016 Jun 10.
Targeting lipid peroxidation and mitochondrial imbalance in Friedreich's ataxia.
Autorzy :
AbetiR; Department of Molecular Neuroscience, UCL, Institute of Neurology, Queen Square, WC1N 3BG London, UK. Uzun E; Department of Molecular Neuroscience, UCL, Institute of Neurology, Queen Square, WC1N 3BG London, UK. Renganathan I; Department of Molecular Neuroscience, UCL, Institute of Neurology, Queen Square, WC1N 3BG London, UK. Honda T; Department of Chemistry, Stony Brook University, Stony Brook, NY 11794, United States. Pook MA; Ataxia Research Group, Division of Biosciences, Department of Life Sciences, College of Health & Life Sciences Synthetic Biology Theme, Institute of Environment, Health & Societies, Brunel University London, Uxbridge UB8 3PH, UK. Giunti P; Department of Molecular Neuroscience, UCL, Institute of Neurology, Queen Square, WC1N 3BG London, UK. Electronic address: .
Pokaż więcej
Źródło :
Pharmacological research [Pharmacol Res] 2015 Sep; Vol. 99, pp. 344-50. Date of Electronic Publication: 2015 Jul 02.
Mitochondrial Ca(2+) in neurodegenerative disorders.
Autorzy :
AbetiR; Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK. Abramov AY; Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK. Electronic address: .
Pokaż więcej
Źródło :
Pharmacological research [Pharmacol Res] 2015 Sep; Vol. 99, pp. 377-81. Date of Electronic Publication: 2015 May 23.
Inhibition of LRRK2 kinase activity stimulates macroautophagy.
Autorzy :
Manzoni C; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK. Electronic address: . Mamais A; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK; Reta Lila Weston Institute and Queen Square Brain Bank, UCL Institute of Neurology, 1 Wakefield Street, London, WC1N 1PJ, UK. Dihanich S; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK. AbetiR; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK. Soutar MPM; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK. Plun-Favreau H; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK. Giunti P; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK. Tooze SA; London Research Institute, Cancer Research UK, Lincoln's Inn Fields, London, WC2A 3LY, UK. Bandopadhyay R; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK; Reta Lila Weston Institute and Queen Square Brain Bank, UCL Institute of Neurology, 1 Wakefield Street, London, WC1N 1PJ, UK. Lewis PA; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK; School of Pharmacy, University of Reading, Whiteknights, Reading, RG6 6AP, UK. Electronic address: .
Pokaż więcej
Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2013 Dec; Vol. 1833 (12), pp. 2900-2910. Date of Electronic Publication: 2013 Aug 01.
Beta-amyloid activates PARP causing astrocytic metabolic failure and neuronal death.
Autorzy :
AbetiR; Department of Cell and Developmental Biology and UCL Consortium for Mitochondrial Research, University College London, Queen Square, London WC1N 3BG, UK. Abramov AY Duchen MR
Comparison between low-level 50 Hz and 900 MHz electromagnetic stimulation on single channel ionic currents and on firing frequency in dorsal root ganglion isolated neurons.
Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies
W koszyku znajdują się zamówienia
W koszyku znajdują się zamówienia do wysłania. Czy chcesz wysłać je do realizacji?
