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Tytuł :
Benzo[a]pyrene and Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide induced locomotor and reproductive senescence and altered biochemical parameters of oxidative damage in Canton-S Drosophila melanogaster .
Autorzy :
Johnson TO; Department of Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, University of Jos, Jos, Nigeria.
Abolaji AO; Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria.
Omale S; Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Jos, Jos, Nigeria.; Africa Center of Excellence in Phytomedicine Research and Development, University of Jos, Jos, Nigeria.
Longdet IY; Department of Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, University of Jos, Jos, Nigeria.
Kutshik RJ; Department of Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, University of Jos, Jos, Nigeria.
Oyetayo BO; Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Nigeria.
Adegboyega AE; Department of Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, University of Jos, Jos, Nigeria.
Sagay A; Department of Obstetrics and Gynecology, College of Health Sciences, University of Jos, Jos, Nigeria.
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Źródło :
Toxicology reports [Toxicol Rep] 2021 Mar 10; Vol. 8, pp. 571-580. Date of Electronic Publication: 2021 Mar 10 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Ethanol exacerbates manganese-induced oxidative/nitrosative stress, pro-inflammatory cytokines, nuclear factor-κB activation, and apoptosis induction in rat cerebellar cortex.
Autorzy :
Nkpaa KW; Environmental Toxicology Unit, Department of Biochemistry, Faculty of Science, University of Port Harcourt, Choba, Rivers State, Nigeria.
Owoeye O; Department of Anatomy, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Amadi BA; Environmental Toxicology Unit, Department of Biochemistry, Faculty of Science, University of Port Harcourt, Choba, Rivers State, Nigeria.
Adedara IA; Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Abolaji AO; Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Wegwu MO; Environmental Toxicology Unit, Department of Biochemistry, Faculty of Science, University of Port Harcourt, Choba, Rivers State, Nigeria.
Farombi EO; Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
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Źródło :
Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2021 Mar; Vol. 35 (3), pp. e22681. Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Chemical composition and acaricidal activity of Eucalyptus globulus essential oil against the vector of tropical bovine piroplasmosis, Rhipicephalus (Boophilus) annulatus.
Autorzy :
Adenubi OT; Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Federal University of Agriculture, Ogun State, PMB 2240, Alabata, Abeokuta, Nigeria. .
Abolaji AO; Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Federal University of Agriculture, Ogun State, PMB 2240, Alabata, Abeokuta, Nigeria.
Salihu T; Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Federal University of Agriculture, Ogun State, PMB 2240, Alabata, Abeokuta, Nigeria.; Nigeria Natural Medicine Development Agency, 9 Kofo Abayomi Street, Victoria Island, Lagos State, Nigeria.
Akande FA; Department of Veterinary Parasitology and Entomology, College of Veterinary Medicine, Federal University of Agriculture, Ogun State, PMB 2240, Alabata, Abeokuta, Nigeria.
Lawal H; Nigeria Natural Medicine Development Agency, 9 Kofo Abayomi Street, Victoria Island, Lagos State, Nigeria.
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Źródło :
Experimental & applied acarology [Exp Appl Acarol] 2021 Feb; Vol. 83 (2), pp. 301-312. Date of Electronic Publication: 2021 Jan 03.
Typ publikacji :
Journal Article
MeSH Terms :
Acaricides*
Babesiosis*
Cattle Diseases*
Eucalyptus*
Oils, Volatile*/pharmacology
Rhipicephalus*
Animals ; Cattle ; Eucalyptus Oil ; Female ; Larva ; Nigeria
Czasopismo naukowe
Tytuł :
Luteolin-Supplemented diets ameliorates Bisphenol A-Induced toxicity in Drosophila melanogaster.
Autorzy :
Adesanoye OA; Drosophila Laboratory, Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Electronic address: .
Abolaji AO; Drosophila Laboratory, Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Electronic address: .
Faloye TR; Drosophila Laboratory, Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Olaoye HO; Drosophila Laboratory, Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Adedara AO; Drosophila Laboratory, Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2020 Aug; Vol. 142, pp. 111478. Date of Electronic Publication: 2020 Jun 03.
Typ publikacji :
Journal Article
MeSH Terms :
Dietary Supplements*
Benzhydryl Compounds/*toxicity
Endocrine Disruptors/*toxicity
Luteolin/*administration & dosage
Phenols/*toxicity
Acetylcholinesterase/drug effects ; Animals ; Cell Survival/drug effects ; Drosophila melanogaster ; Locomotion/drug effects ; Oxidative Stress/drug effects
Czasopismo naukowe
Tytuł :
D-Penicillamine prolongs survival and lessens copper-induced toxicity in Drosophila melanogaster .
Autorzy :
Abolaji AO; Department of Biochemistry, Drosophila Laboratory, Molecular Drug Metabolism and Toxicology Unit, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Fasae KD; Department of Biochemistry, Drosophila Laboratory, Molecular Drug Metabolism and Toxicology Unit, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Iwezor CE; Department of Biochemistry, Drosophila Laboratory, Molecular Drug Metabolism and Toxicology Unit, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Farombi EO; Department of Biochemistry, Drosophila Laboratory, Molecular Drug Metabolism and Toxicology Unit, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
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Źródło :
Toxicology research [Toxicol Res (Camb)] 2020 Jun 03; Vol. 9 (4), pp. 346-352. Date of Electronic Publication: 2020 Jun 03 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Rescue role of hesperidin in 4-vinylcyclohexene diepoxide-induced toxicity in the brain, ovary and uterus of wistar rats.
Autorzy :
Abolaji AO; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria, Phone: +2348068614194.
Omozokpia MU; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Oluwamuyide OJ; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Akintola TE; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Farombi EO; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria, Phone: +2348023470333.
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Źródło :
Journal of basic and clinical physiology and pharmacology [J Basic Clin Physiol Pharmacol] 2020 Mar 11; Vol. 31 (2). Date of Electronic Publication: 2020 Mar 11.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*drug effects
Cyclohexenes/*toxicity
Hesperidin/*pharmacology
Ovary/*drug effects
Uterus/*drug effects
Vinyl Compounds/*toxicity
Animals ; Anti-Inflammatory Agents/pharmacology ; Antioxidants/metabolism ; Antioxidants/pharmacology ; Brain/pathology ; Female ; Glutathione/metabolism ; Ovary/pathology ; Oxidative Stress/drug effects ; Rats ; Rats, Wistar ; Uterus/pathology
Czasopismo naukowe
Tytuł :
Curcumin attenuates copper-induced oxidative stress and neurotoxicity in Drosophila melanogaster .
Autorzy :
Abolaji AO; Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, College of Medicine, University of Ibadan, Nigeria.
Fasae KD; Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, College of Medicine, University of Ibadan, Nigeria.
Iwezor CE; Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, College of Medicine, University of Ibadan, Nigeria.
Aschner M; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, USA.
Farombi EO; Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, College of Medicine, University of Ibadan, Nigeria.
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Źródło :
Toxicology reports [Toxicol Rep] 2020 Jan 27; Vol. 7, pp. 261-268. Date of Electronic Publication: 2020 Jan 27 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Protective role of resveratrol, a natural polyphenol, in sodium fluoride-induced toxicity in Drosophila melanogaster .
Autorzy :
Abolaji AO; Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan 20028, Nigeria.
Ajala VO; Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan 20028, Nigeria.
Adigun JO; Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan 20028, Nigeria.
Adedara IA; Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan 20028, Nigeria.
Kinyi HW; Department of Biochemistry, School of Biomedical Sciences, Kampala International University, Kampala 20131, Uganda.
Farombi EO; Department of Biochemistry, Molecular Drug Metabolism and Toxicology Unit, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan 20028, Nigeria.
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Źródło :
Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2019 Dec; Vol. 244 (18), pp. 1688-1694. Date of Electronic Publication: 2019 Nov 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antioxidants/*pharmacology
Drosophila melanogaster/*drug effects
Resveratrol/*pharmacology
Sodium Fluoride/*toxicity
Acetylcholinesterase/drug effects ; Acetylcholinesterase/metabolism ; Animals ; Dose-Response Relationship, Drug ; Oxidative Stress/drug effects ; Sodium Fluoride/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Ethanol Exacerbates Manganese-Induced Neurobehavioral Deficits, Striatal Oxidative Stress, and Apoptosis Via Regulation of p53, Caspase-3, and Bax/Bcl-2 Ratio-Dependent Pathway.
Autorzy :
Nkpaa KW; Environmental Toxicology Unit, Department of Biochemistry, Faculty of Science, University of Port Harcourt, P.M.B 5323, Choba, Rivers State, Nigeria. .
Awogbindin IO; Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Amadi BA; Environmental Toxicology Unit, Department of Biochemistry, Faculty of Science, University of Port Harcourt, P.M.B 5323, Choba, Rivers State, Nigeria.
Abolaji AO; Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Adedara IA; Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Wegwu MO; Environmental Toxicology Unit, Department of Biochemistry, Faculty of Science, University of Port Harcourt, P.M.B 5323, Choba, Rivers State, Nigeria. .
Farombi EO; Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
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Źródło :
Biological trace element research [Biol Trace Elem Res] 2019 Sep; Vol. 191 (1), pp. 135-148. Date of Electronic Publication: 2018 Nov 28.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Behavior, Animal/*drug effects
Caspase 3/*metabolism
Corpus Striatum/*metabolism
Ethanol/*adverse effects
Manganese/*toxicity
Oxidative Stress/*drug effects
Proto-Oncogene Proteins c-bcl-2/*metabolism
Signal Transduction/*drug effects
Tumor Suppressor Protein p53/*metabolism
bcl-2-Associated X Protein/*metabolism
Animals ; Corpus Striatum/pathology ; Ethanol/pharmacology ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Productivity of CNPq Researchers from Different Fields in Biomedical Sciences: The Need for Objective Bibliometric Parameters-A Report from Brazil.
Autorzy :
Kamdem JP; Centro de Ciências Biológicas e da Saúde-CCBS, Departamento de Ciências Biológicas, Universidade Regional do Cariri (URCA), Pimenta, Crato, CE, CEP 63105-000, Brazil. .; PGP Education in Science, Chemistry of Life and Health, Federal University of Rio Grande do Sul, Porto Alegre, RS, CEP 90035-003, Brazil. .; Departamento de Bioquímica e Biologia Molecular, Federal University of Santa Maria, Santa Maria, RS, Brazil. .
Roos DH; Universidade Federal do Pampa-UNIPAMPA, Campus Uruguaiana BR-472 km 7, Uruguaiana, RS, CEP 97500-970, Brazil.
Sanmi AA; Department of Biochemistry, Ladoke Akintola University of Technology, PMB 4000, Ogbomoso, Nigeria.
Calabró L; PGP Education in Science, Chemistry of Life and Health, Federal University of Rio Grande do Sul, Porto Alegre, RS, CEP 90035-003, Brazil.
Abolaji AO; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
de Oliveira CS; Departamento de Bioquímica e Biologia Molecular, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Barros LM; Centro de Ciências Biológicas e da Saúde-CCBS, Departamento de Ciências Biológicas, Universidade Regional do Cariri (URCA), Pimenta, Crato, CE, CEP 63105-000, Brazil.
Duarte AE; Centro de Ciências Biológicas e da Saúde-CCBS, Departamento de Ciências Biológicas, Universidade Regional do Cariri (URCA), Pimenta, Crato, CE, CEP 63105-000, Brazil.
Barbosa NV; Departamento de Bioquímica e Biologia Molecular, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Souza DO; PGP Education in Science, Chemistry of Life and Health, Federal University of Rio Grande do Sul, Porto Alegre, RS, CEP 90035-003, Brazil.
Rocha JBT; Departamento de Bioquímica e Biologia Molecular, Federal University of Santa Maria, Santa Maria, RS, Brazil. .
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Źródło :
Science and engineering ethics [Sci Eng Ethics] 2019 Aug; Vol. 25 (4), pp. 1037-1055. Date of Electronic Publication: 2018 Feb 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bibliometrics*
Research Support as Topic*
Biological Science Disciplines/*classification
Biomedical Research/*classification
Biomedical Research/*economics
Biomedical Research/*standards
Research Personnel/*classification
Authorship/standards ; Biological Science Disciplines/economics ; Brazil ; Databases, Bibliographic ; Efficiency ; Female ; Humans ; Male ; Research Personnel/economics ; Research Personnel/standards
Czasopismo naukowe
Tytuł :
Neuroprotective role of 6-Gingerol-rich fraction of Zingiber officinale (Ginger) against acrylonitrile-induced neurotoxicity in male Wistar rats.
Autorzy :
Farombi EO; Molecular Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria, Phone: +2348023470333, Fax: 234-2-8103043.
Abolaji AO; Molecular Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Adetuyi BO; Molecular Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Awosanya O; Molecular Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Fabusoro M; Molecular Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
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Źródło :
Journal of basic and clinical physiology and pharmacology [J Basic Clin Physiol Pharmacol] 2018 Dec 22; Vol. 30 (3). Date of Electronic Publication: 2018 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
Acrylonitrile/*pharmacology
Catechols/*pharmacology
Fatty Alcohols/*pharmacology
Ginger/*chemistry
Neuroprotection/*drug effects
Animals ; Antioxidants/metabolism ; Catalase/metabolism ; Cerebral Cortex/drug effects ; Cerebral Cortex/metabolism ; Glutathione/metabolism ; Glutathione Peroxidase/metabolism ; Glutathione Transferase/metabolism ; Inflammation/drug therapy ; Inflammation/metabolism ; Interleukin-6/metabolism ; Lipid Peroxidation/drug effects ; Male ; Malondialdehyde/metabolism ; Nitric Oxide/metabolism ; Oxidative Stress/drug effects ; Plant Extracts/pharmacology ; Rats ; Rats, Wistar ; Superoxide Dismutase/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Resveratrol prolongs lifespan and improves 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced oxidative damage and behavioural deficits in Drosophila melanogaster.
Autorzy :
Abolaji AO; Molecular Drug Metabolism and Toxicology Unit, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria. Electronic address: ao.abolaji@ui.edu.ng.
Adedara AO; Molecular Drug Metabolism and Toxicology Unit, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Adie MA; Molecular Drug Metabolism and Toxicology Unit, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Vicente-Crespo M; Mzima International Research Unit, Kampala, Uganda; DrosAfrica, UK.
Farombi EO; Molecular Drug Metabolism and Toxicology Unit, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2018 Sep 05; Vol. 503 (2), pp. 1042-1048. Date of Electronic Publication: 2018 Jun 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/*adverse effects
Antioxidants/*pharmacology
Drosophila melanogaster/*drug effects
Oxidative Stress/*drug effects
Resveratrol/*pharmacology
Acetylcholinesterase/metabolism ; Animals ; Behavior, Animal/drug effects ; Catalase/metabolism ; Cell Survival/drug effects ; Drosophila melanogaster/physiology ; Glutathione Transferase/metabolism ; Hydrogen Peroxide/metabolism ; Longevity/drug effects ; Nitric Oxide/metabolism ; Parkinson Disease, Secondary/chemically induced ; Parkinson Disease, Secondary/metabolism
Czasopismo naukowe
Tytuł :
Curcumin-supplemented diets improve antioxidant enzymes and alter acetylcholinesterase genes expression level in Drosophila melanogaster model.
Autorzy :
Akinyemi AJ; Department of Biochemistry, College of Sciences, Afe Babalola University Ado-Ekiti, Ado Ekiti, Ekiti State, Nigeria. .; Department of Biochemistry, Federal University of Technology, Akure, Ondo-State, Nigeria. .
Oboh G; Department of Biochemistry, Federal University of Technology, Akure, Ondo-State, Nigeria.
Ogunsuyi O; Department of Biochemistry, Federal University of Technology, Akure, Ondo-State, Nigeria.; Department of Biomedical Technology, Federal University of Technology, Akure, P.M.B. 704, Nigeria.
Abolaji AO; Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Udofia A; Department of Bioscience Center, International Institute of Tropical Agriculture, Ibadan, Nigeria.
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Źródło :
Metabolic brain disease [Metab Brain Dis] 2018 Apr; Vol. 33 (2), pp. 369-375. Date of Electronic Publication: 2017 Aug 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcholinesterase/*genetics
Antioxidants/*metabolism
Curcumin/*pharmacology
Drosophila melanogaster/*drug effects
Gene Expression Regulation/*drug effects
Acetylcholinesterase/metabolism ; Animals ; Cholinesterase Inhibitors/pharmacology ; Curcuma ; Dietary Supplements ; Drosophila melanogaster/genetics ; Longevity/drug effects ; Plant Extracts/pharmacology ; Superoxide Dismutase/drug effects ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Garcinia kola seed biflavonoid fraction (Kolaviron), increases longevity and attenuates rotenone-induced toxicity in Drosophila melanogaster.
Autorzy :
Farombi EO; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria. Electronic address: .
Abolaji AO; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Farombi TH; Deparment of Medicine, College of Medicine, University of Ibadan, University College Hospital, Ibadan, Nigeria.
Oropo AS; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Owoje OA; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Awunah MT; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
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Źródło :
Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2018 Feb; Vol. 145, pp. 39-45. Date of Electronic Publication: 2018 Jan 11.
Typ publikacji :
Journal Article
MeSH Terms :
Drosophila melanogaster/*drug effects
Flavonoids/*pharmacology
Garcinia kola/*embryology
Longevity/*drug effects
Rotenone/*toxicity
Seeds/*chemistry
Acetylcholinesterase/metabolism ; Animals ; Anti-Inflammatory Agents/isolation & purification ; Anti-Inflammatory Agents/pharmacology ; Antioxidants/isolation & purification ; Antioxidants/pharmacology ; Catalase/metabolism ; Dose-Response Relationship, Drug ; Drosophila melanogaster/metabolism ; Female ; Flavonoids/isolation & purification ; Glutathione Transferase/metabolism ; Hydrogen Peroxide/metabolism ; Locomotion/drug effects ; Male ; Nitrates/metabolism ; Nitric Oxide/metabolism ; Nitrites/metabolism ; Oxidative Stress/drug effects ; Sulfhydryl Compounds/metabolism
Czasopismo naukowe
Tytuł :
4-Vinylcyclohexene diepoxide disrupts sperm characteristics, endocrine balance and redox status in testes and epididymis of rats.
Autorzy :
Adedara IA; a Department of Biochemistry, Drug Metabolism & Toxicology Research Laboratories, College of Medicine , University of Ibadan , Ibadan , Nigeria.
Abolaji AO; a Department of Biochemistry, Drug Metabolism & Toxicology Research Laboratories, College of Medicine , University of Ibadan , Ibadan , Nigeria.
Ladipo EO; a Department of Biochemistry, Drug Metabolism & Toxicology Research Laboratories, College of Medicine , University of Ibadan , Ibadan , Nigeria.
Fatunmibi OJ; a Department of Biochemistry, Drug Metabolism & Toxicology Research Laboratories, College of Medicine , University of Ibadan , Ibadan , Nigeria.
Abajingin AO; a Department of Biochemistry, Drug Metabolism & Toxicology Research Laboratories, College of Medicine , University of Ibadan , Ibadan , Nigeria.
Farombi EO; a Department of Biochemistry, Drug Metabolism & Toxicology Research Laboratories, College of Medicine , University of Ibadan , Ibadan , Nigeria.
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Źródło :
Redox report : communications in free radical research [Redox Rep] 2017 Nov; Vol. 22 (6), pp. 388-398. Date of Electronic Publication: 2016 Nov 28.
Typ publikacji :
Journal Article
MeSH Terms :
Cyclohexenes/*toxicity
Epididymis/*drug effects
Epididymis/*metabolism
Spermatozoa/*drug effects
Spermatozoa/*metabolism
Testis/*drug effects
Testis/*metabolism
Vinyl Compounds/*toxicity
Animals ; Caspase 3/metabolism ; Caspase 9/metabolism ; Catalase/metabolism ; Male ; Oxidation-Reduction/drug effects ; Oxidative Stress/drug effects ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Hesperidin, a citrus bioflavonoid, alleviates trichloroethylene-induced oxidative stress in Drosophila melanogaster.
Autorzy :
Abolaji AO; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria. Electronic address: .
Babalola OV; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Adegoke AK; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Farombi EO; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria. Electronic address: /.
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Źródło :
Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2017 Oct; Vol. 55, pp. 202-207. Date of Electronic Publication: 2017 Sep 01.
Typ publikacji :
Journal Article
MeSH Terms :
Antioxidants/*administration & dosage
Drosophila melanogaster/*drug effects
Hesperidin/*administration & dosage
Trichloroethylene/*adverse effects
Acetylcholinesterase/metabolism ; Animals ; Antioxidants/pharmacology ; Catalase/metabolism ; Drosophila Proteins/metabolism ; Drosophila melanogaster/metabolism ; Gene Expression Regulation/drug effects ; Glutathione Transferase/metabolism ; Hesperidin/pharmacology ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Protective properties of 6-gingerol-rich fraction from Zingiber officinale (Ginger) on chlorpyrifos-induced oxidative damage and inflammation in the brain, ovary and uterus of rats.
Autorzy :
Abolaji AO; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria. Electronic address: .
Ojo M; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Afolabi TT; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Arowoogun MD; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Nwawolor D; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Farombi EO; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2017 May 25; Vol. 270, pp. 15-23. Date of Electronic Publication: 2017 Mar 31.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*drug effects
Catechols/*therapeutic use
Fatty Alcohols/*therapeutic use
Ginger/*chemistry
Ovary/*drug effects
Oxidative Stress/*drug effects
Plant Extracts/*pharmacology
Uterus/*drug effects
ADAM17 Protein/drug effects ; Animals ; Body Weight/drug effects ; Brain/pathology ; Chlorpyrifos/toxicity ; Female ; Inflammation/drug therapy ; Ovary/pathology ; Plant Extracts/therapeutic use ; Rats ; Rats, Wistar ; Uterus/pathology
Czasopismo naukowe
Tytuł :
Insecticide chlorpyrifos and fungicide carbendazim, common food contaminants mixture, induce hepatic, renal, and splenic oxidative damage in female rats.
Autorzy :
Abolaji AO; Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Awogbindin IO; Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Adedara IA; Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Farombi EO; Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
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Źródło :
Human & experimental toxicology [Hum Exp Toxicol] 2017 May; Vol. 36 (5), pp. 483-493. Date of Electronic Publication: 2016 Jun 06.
Typ publikacji :
Journal Article
MeSH Terms :
Benzimidazoles/*toxicity
Carbamates/*toxicity
Chlorpyrifos/*toxicity
Environmental Pollutants/*toxicity
Fungicides, Industrial/*toxicity
Insecticides/*toxicity
Alanine Transaminase/blood ; Animals ; Aspartate Aminotransferases/blood ; Catalase/metabolism ; Drug Synergism ; Female ; Food Contamination ; Glutathione Transferase/metabolism ; Hydrogen Peroxide/metabolism ; Kidney/drug effects ; Kidney/metabolism ; Kidney/pathology ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Nitric Oxide/metabolism ; Oxidative Stress/drug effects ; Peroxidase/metabolism ; Rats, Wistar ; Spleen/drug effects ; Spleen/metabolism ; Spleen/pathology ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Dietary consumption of monosodium L-glutamate induces adaptive response and reduction in the life span of Drosophila melanogaster.
Autorzy :
Abolaji AO; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Olaiya CO; Nutritional and Industrial Biochemistry Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Oluwadahunsi OJ; Department of Biochemistry, Adekunle Ajasin University, Akungba-Akoko, Ondo State, Nigeria.
Farombi EO; Drug Metabolism and Molecular Toxicology Research Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
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Źródło :
Cell biochemistry and function [Cell Biochem Funct] 2017 Apr; Vol. 35 (3), pp. 164-170. Date of Electronic Publication: 2017 Mar 16.
Typ publikacji :
Journal Article
MeSH Terms :
Diet*
Adaptation, Physiological/*drug effects
Antioxidants/*metabolism
Drosophila melanogaster/*growth & development
Flavoring Agents/*pharmacology
Oxidative Stress/*drug effects
Sodium Glutamate/*pharmacology
Acetylcholinesterase/metabolism ; Animals ; Catalase/metabolism ; Drosophila melanogaster/drug effects ; Drosophila melanogaster/metabolism ; Glutathione Transferase/metabolism ; Sulfhydryl Compounds/metabolism ; Superoxide Dismutase/metabolism
Czasopismo naukowe

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