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Tytuł:
Inhibitory Activity of 4-Benzylidene Oxazolones Derivatives of Cinnamic Acid on Human Acetylcholinesterase and Cognitive Improvements in a Mouse Model.
Autorzy:
Ramírez-Ruiz AM; Facultad de Medicina y Psicología, Universidad Autónoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana 22424, BC, Mexico.; Facultad de Ciencias Químicas e Ingeniería, Universidad Autónoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana 22424, BC, Mexico.
Ávila-Cossío ME; Centro de Graduados e Investigación en Química, Tecnológico Nacional de Mexico/Instituto Tecnológico de Tijuana, Tijuana 22510, BC, Mexico.
Estolano-Cobián A; Facultad de Ciencias Químicas e Ingeniería, Universidad Autónoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana 22424, BC, Mexico.
Cornejo-Bravo JM; Facultad de Ciencias Químicas e Ingeniería, Universidad Autónoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana 22424, BC, Mexico.
Martinez AL; Facultad de Medicina y Psicología, Universidad Autónoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana 22424, BC, Mexico.
Córdova-Guerrero I; Facultad de Ciencias Químicas e Ingeniería, Universidad Autónoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana 22424, BC, Mexico.
Cota-Ramírez BR; Facultad de Ciencias Químicas e Ingeniería, Universidad Autónoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana 22424, BC, Mexico.
Carranza-Ambriz KP; Facultad de Medicina y Psicología, Universidad Autónoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana 22424, BC, Mexico.
Rivero IA; Centro de Graduados e Investigación en Química, Tecnológico Nacional de Mexico/Instituto Tecnológico de Tijuana, Tijuana 22510, BC, Mexico.
Serrano-Medina A; Facultad de Medicina y Psicología, Universidad Autónoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana 22424, BC, Mexico.; Facultad de Ciencias Químicas e Ingeniería, Universidad Autónoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana 22424, BC, Mexico.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Nov 02; Vol. 28 (21). Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/metabolism
Alzheimer Disease*
Animals ; Mice ; Humans ; Molecular Docking Simulation ; Oxazolone ; Cholinesterase Inhibitors/chemistry ; Disease Models, Animal ; Cognition ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Strategies for enhanced bioavailability of oxime reactivators in the central nervous system.
Autorzy:
Prchalova E; Faculty of Science, Department of Chemistry, University of Hradec Kralove, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.
Kohoutova Z; Faculty of Science, Department of Chemistry, University of Hradec Kralove, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.
Knittelova K; Faculty of Science, Department of Chemistry, University of Hradec Kralove, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.
Malinak D; Faculty of Science, Department of Chemistry, University of Hradec Kralove, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic. .; Biomedical Research Centre, University Hospital in Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic. .
Musilek K; Faculty of Science, Department of Chemistry, University of Hradec Kralove, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic. .; Biomedical Research Centre, University Hospital in Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic. .
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Źródło:
Archives of toxicology [Arch Toxicol] 2023 Nov; Vol. 97 (11), pp. 2839-2860. Date of Electronic Publication: 2023 Aug 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Acetylcholinesterase*
Central Nervous System*
Humans ; Biological Availability ; Blood-Brain Barrier ; Biological Transport
Czasopismo naukowe
Szczegóły
Tytuł:
Immobilized acetylcholinesterase in magnetic nanoparticles for in-line inhibition studies using a capillary electrophoresis system.
Autorzy:
Siebert DA; Laboratório de Eletroforese Capilar, Departamento de Química, Universidade Federal de Santa Catarina, Trindade, CEP 88040-900, Florianópolis, SC, Brazil.
Caon NB; Laboratório de Estudo em Materiais Poliméricos, Departamento de Química, Universidade Federal de Santa Catarina, Trindade, CEP 88040-900, Florianópolis, SC, Brazil.
Alberton MD; Laboratório de Pesquisa em Produtos Naturais, Universidade Regional de Blumenau, Rua São Paulo 2171, CEP 89030-000, Blumenau, SC, Brazil.
Vitali L; Laboratório de Eletroforese Capilar, Departamento de Química, Universidade Federal de Santa Catarina, Trindade, CEP 88040-900, Florianópolis, SC, Brazil.
Parize AL; Laboratório de Estudo em Materiais Poliméricos, Departamento de Química, Universidade Federal de Santa Catarina, Trindade, CEP 88040-900, Florianópolis, SC, Brazil.
Micke GA; Laboratório de Eletroforese Capilar, Departamento de Química, Universidade Federal de Santa Catarina, Trindade, CEP 88040-900, Florianópolis, SC, Brazil. Electronic address: .
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Źródło:
Analytica chimica acta [Anal Chim Acta] 2023 Sep 22; Vol. 1275, pp. 341566. Date of Electronic Publication: 2023 Jun 27.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*
Magnetite Nanoparticles*
Enzymes, Immobilized ; Magnets ; Electrophoresis, Capillary/methods
Czasopismo naukowe
Szczegóły
Tytuł:
Acetylcholinesterase inhibition protects against trastuzumab-induced cardiotoxicity through reducing multiple programmed cell death pathways.
Autorzy:
Khuanjing T; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Maneechote C; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Ongnok B; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Prathumsap N; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Arinno A; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Chunchai T; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Arunsak B; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Chattipakorn SC; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.; Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Chiang Mai, 50200, Thailand.
Chattipakorn N; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand. .; Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand. .; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand. .
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Źródło:
Molecular medicine (Cambridge, Mass.) [Mol Med] 2023 Sep 11; Vol. 29 (1), pp. 123. Date of Electronic Publication: 2023 Sep 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcholinesterase*
Cardiotoxicity*/drug therapy
Cardiotoxicity*/etiology
Male ; Animals ; Rats ; Rats, Wistar ; Trastuzumab/adverse effects ; Donepezil ; Apoptosis ; Inflammation
Czasopismo naukowe
Szczegóły
Tytuł:
L-carnitine Modulates Cognitive Impairment Induced by Doxorubicin and Cyclophosphamide in Rats; Insights to Oxidative Stress, Inflammation, Synaptic Plasticity, Liver/brain, and Kidney/brain Axes.
Autorzy:
Morid OF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, 11566, Egypt.
Menze ET; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, 11566, Egypt.
Tadros MG; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, 11566, Egypt.
George MY; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, 11566, Egypt. .
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Źródło:
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology [J Neuroimmune Pharmacol] 2023 Sep; Vol. 18 (3), pp. 310-326. Date of Electronic Publication: 2023 May 04.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/metabolism
Acetylcholinesterase*/pharmacology
Cognitive Dysfunction*/chemically induced
Cognitive Dysfunction*/drug therapy
Cognitive Dysfunction*/metabolism
Humans ; Rats ; Animals ; Carnitine/adverse effects ; Oxidative Stress ; Antioxidants/pharmacology ; Doxorubicin/toxicity ; Brain ; Inflammation/chemically induced ; Inflammation/drug therapy ; Inflammation/metabolism ; Liver/metabolism ; Kidney/metabolism ; Kidney/pathology ; Cyclophosphamide/toxicity
Czasopismo naukowe
Szczegóły
Tytuł:
Comparative gross anatomy of epicardiac ganglionated nerve plexi on the human and sheep cardiac ventricles.
Autorzy:
Saburkina I; Institute of Anatomy, Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Pauziene N; Institute of Anatomy, Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Solomon OI; Institute of Anatomy, Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Rysevaite-Kyguoliene K; Institute of Anatomy, Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Pauza DH; Institute of Anatomy, Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania.
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Źródło:
Anatomical record (Hoboken, N.J. : 2007) [Anat Rec (Hoboken)] 2023 Sep; Vol. 306 (9), pp. 2302-2312. Date of Electronic Publication: 2022 Oct 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Heart Ventricles*/innervation
Acetylcholinesterase*
Humans ; Animals ; Infant, Newborn ; Sheep ; Heart/physiology ; Ganglia/anatomy & histology ; Neurons
Czasopismo naukowe
Szczegóły
Tytuł:
Combinative effects of akarkara root-derived metabolites on anti-inflammatory and anti-alzheimer key enzymes: integrating bioassay-guided fractionation, GC-MS analysis, and in silico studies.
Autorzy:
Ibrahim RM; Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy Street, Cairo, 11562, Egypt.
Abdel-Baki PM; Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy Street, Cairo, 11562, Egypt. .
Elmasry GF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo, 11562, Egypt. .
El-Rashedy AA; Natural and Microbial Products Department, National Research Center (NRC), Dokki, Giza, 12622, Egypt.
Mahdy NE; Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy Street, Cairo, 11562, Egypt.
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Źródło:
BMC complementary medicine and therapies [BMC Complement Med Ther] 2023 Nov 17; Vol. 23 (1), pp. 413. Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/chemistry
Acetylcholinesterase*
Molecular Docking Simulation ; Gas Chromatography-Mass Spectrometry ; Cyclooxygenase 2/metabolism ; Methylene Chloride ; Plant Extracts/chemistry ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/chemistry ; Anti-Bacterial Agents ; Biological Assay ; Cholinergic Antagonists
Czasopismo naukowe
Szczegóły
Tytuł:
Selective modulation of alkali metal ions on acetylcholinesterase.
Autorzy:
Mu X; State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. .
Yuan S; State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. .; University of Chinese Academy of Sciences, Beijing, China.
Zhang D; State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. .
Lai R; State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. .
Liao C; State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. .
Li G; State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. .
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Źródło:
Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2023 Nov 15; Vol. 25 (44), pp. 30308-30318. Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/chemistry
Metals, Alkali*/chemistry
Humans ; Lithium/chemistry ; Sodium/chemistry ; Cations
Czasopismo naukowe
Szczegóły
Tytuł:
Limited effect of sugammadex on postoperative pulmonary complications in patients undergoing spine surgery in prone position intraoperatively: A retrospective analysis of matched cohort data.
Autorzy:
Ko E; Department of Anesthesiology and Pain Medicine, Korea University Anam Hospital, Seoul, South Korea.
Kwak JS; Department of Anesthesiology and Pain Medicine, Korea University Anam Hospital, Seoul, South Korea.
Park H; Department of Anesthesiology and Pain Medicine, Korea University Anam Hospital, Seoul, South Korea.
Lim CH; Department of Anesthesiology and Pain Medicine, College of Medicine, Korea University, Seoul, South Korea.
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Źródło:
Medicine [Medicine (Baltimore)] 2023 Nov 03; Vol. 102 (44), pp. e35858.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*
Respiratory Insufficiency*
Adult ; Humans ; Retrospective Studies ; Sugammadex ; Hospital Mortality ; Prone Position ; Postoperative Complications ; Cholinesterase Inhibitors
Czasopismo naukowe
Szczegóły
Tytuł:
Choline-acetyltransferase (ChAT) and acetylcholinesterase (AChE) in the human infant dorsal motor nucleus of the Vagus (DMNV), and alterations according to sudden infant death syndrome (SIDS) category.
Autorzy:
Joda M; Discipline of Medicine, Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia.
Waters KA; Discipline of Medicine, Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia; Discipline of Child and Adolescent Health, Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia.
Machaalani R; Discipline of Medicine, Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia; Discipline of Child and Adolescent Health, Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, NSW 2006, Australia. Electronic address: .
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Źródło:
Neurobiology of disease [Neurobiol Dis] 2023 Nov; Vol. 188, pp. 106319. Date of Electronic Publication: 2023 Oct 07.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*
Sudden Infant Death*
Humans ; Infant ; Male ; Butyrylcholinesterase ; Choline ; Choline O-Acetyltransferase ; Cholinergic Agents
Czasopismo naukowe
Szczegóły
Tytuł:
Organophosphorus and carbamate pesticides: Molecular toxicology and laboratory testing.
Autorzy:
Kaur S; Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh 160012, India.
Chowdhary S; Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh 160012, India.
Kumar D; Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh 160012, India. Electronic address: .
Bhattacharyya R; Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh 160012, India. Electronic address: .
Banerjee D; Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh 160012, India. Electronic address: .
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Źródło:
Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2023 Nov 01; Vol. 551, pp. 117584. Date of Electronic Publication: 2023 Oct 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Acetylcholinesterase*/metabolism
Pesticides*/toxicity
Humans ; Carbamates/toxicity
Czasopismo naukowe
Szczegóły
Tytuł:
Design, Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Study of Benzimidazole-Based Oxazole Analogues: A Promising Acetylcholinesterase and Butyrylcholinesterase Inhibitors.
Autorzy:
Hussain R; Department of Chemistry, Hazara University, Mansehra 21120, Pakistan.
Rahim F; Department of Chemistry, Hazara University, Mansehra 21120, Pakistan.
Ullah H; Department of Chemistry, University of Okara, Okara 56130, Pakistan.
Khan S; Department of Chemistry, Abbottabad University of Science and Technology (AUST), Abbottabad 22500, Pakistan.
Sarfraz M; Department of Zoology, Wildlife and Fisheries, University of Agriculture Faisalabad, Sub Campus Toba Tek Singh, Faisalabad 36050, Pakistan.
Iqbal R; Department of Agroecology-Climate and Water, Aarhus University, Blichers Allé 20, 8830 Tjele, Denmark.; Department of Agronomy, Faculty of Agriculture and Environment, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Suleman F; Department of Botany, Government College University, Lahore 54000, Pakistan.
Al-Sadoon MK; Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Oct 10; Vol. 28 (20). Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/metabolism
Alzheimer Disease*/drug therapy
Alzheimer Disease*/metabolism
Humans ; Aged ; Butyrylcholinesterase/chemistry ; Molecular Docking Simulation ; Quality of Life ; Cholinesterase Inhibitors/chemistry ; Structure-Activity Relationship ; Benzimidazoles/chemistry ; Molecular Structure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
New Benzamides as Multi-Targeted Compounds: A Study on Synthesis, AChE and BACE1 Inhibitory Activity and Molecular Docking.
Autorzy:
Drozdowska D; Department of Organic Chemistry, Medical University of Białystok, Mickiewicza Street 2A, 15-222 Białystok, Poland.
Maliszewski D; Department of Organic Chemistry, Medical University of Białystok, Mickiewicza Street 2A, 15-222 Białystok, Poland.
Wróbel A; Department of Organic Chemistry, Medical University of Białystok, Mickiewicza Street 2A, 15-222 Białystok, Poland.
Ratkiewicz A; Department of Physical Chemistry, Faculty of Chemistry, University of Białystok, Ciołkowskiego 1K Street, 15-245 Białystok, Poland.
Sienkiewicz M; Department of Physical Chemistry, Faculty of Chemistry, University of Białystok, Ciołkowskiego 1K Street, 15-245 Białystok, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 04; Vol. 24 (19). Date of Electronic Publication: 2023 Oct 04.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/metabolism
Alzheimer Disease*/drug therapy
Humans ; Molecular Docking Simulation ; Cholinesterase Inhibitors/pharmacology ; Amyloid Precursor Protein Secretases/metabolism ; Aspartic Acid Endopeptidases/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chronic exposure to bisphenol A induces behavioural, neurochemical, histological, and ultrastructural alterations in the ganglia tissue of the date mussels Lithophaga lithophaga.
Autorzy:
Abd Elkader HAE; Zoology, Biological and Geological Sciences Department, Faculty of Education, Alexandria University, Alexandria, Egypt. .
Al-Shami AS; Zoology Department, Faculty of Science, Alexandria University, Alexandria, Egypt.; Biotechnology Department, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt.
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Źródło:
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2023 Oct; Vol. 30 (50), pp. 109041-109062. Date of Electronic Publication: 2023 Sep 28.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*
Mytilidae*
Animals ; Humans ; Phenols/toxicity ; Benzhydryl Compounds/toxicity
Czasopismo naukowe
Szczegóły
Tytuł:
1,2,3-Triazolo[4,5-b]aminoquinolines: Design, synthesis, structure, acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity, and molecular docking of novel modified tacrines.
Autorzy:
Kappenberg YG; Núcleo de Química de Heterociclos (NUQUIMHE), Departamento de Química, Universidade Federal de Santa Maria, 97105-900, Santa Maria, RS, Brazil.
Nogara PA; Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Santa Maria, 97105-900 - Santa Maria, RS, Brazil; Instituto Federal Sul-Rio-Grandense (IFSul), 96418-400- Bagé, RS, Brazil.
Stefanello FS; Núcleo de Química de Heterociclos (NUQUIMHE), Departamento de Química, Universidade Federal de Santa Maria, 97105-900, Santa Maria, RS, Brazil.
Delgado CP; Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Santa Maria, 97105-900 - Santa Maria, RS, Brazil.
Rocha JBT; Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Santa Maria, 97105-900 - Santa Maria, RS, Brazil.
Zanatta N; Núcleo de Química de Heterociclos (NUQUIMHE), Departamento de Química, Universidade Federal de Santa Maria, 97105-900, Santa Maria, RS, Brazil.
Martins MAP; Núcleo de Química de Heterociclos (NUQUIMHE), Departamento de Química, Universidade Federal de Santa Maria, 97105-900, Santa Maria, RS, Brazil.
Bonacorso HG; Núcleo de Química de Heterociclos (NUQUIMHE), Departamento de Química, Universidade Federal de Santa Maria, 97105-900, Santa Maria, RS, Brazil. Electronic address: .
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Źródło:
Bioorganic chemistry [Bioorg Chem] 2023 Oct; Vol. 139, pp. 106704. Date of Electronic Publication: 2023 Jul 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcholinesterase*/metabolism
Butyrylcholinesterase*/metabolism
Tacrine/pharmacology ; Molecular Docking Simulation ; Structure-Activity Relationship ; Cholinesterase Inhibitors/chemistry ; Molecular Structure
Czasopismo naukowe
Szczegóły
Tytuł:
Cholinesterase Inhibitory and Anti-Inflammatory Activity of the Naphtho- and Thienobenzo-Triazole Photoproducts: Experimental and Computational Study.
Autorzy:
Mlakić M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10000 Zagreb, Croatia.
Faraho I; Pharmacology In Vitro, Selvita Ltd., Prilaz baruna Filipovića 29, HR-10000 Zagreb, Croatia.
Odak I; Department of Chemistry, Faculty of Science and Education, University of Mostar, Matice Hrvatske bb, 88000 Mostar, Bosnia and Herzegovina.
Kovačević B; Group for Computational Life Sciences, Division of Physical Chemistry, Ruđer Bošković Institute, Bijenička Cesta 54, HR-10000 Zagreb, Croatia.
Raspudić A; Department of Chemistry, Faculty of Science and Education, University of Mostar, Matice Hrvatske bb, 88000 Mostar, Bosnia and Herzegovina.
Šagud I; Croatian Agency for Medicinal Products and Medical Devices, Ksaverska Cesta 4, HR-10000 Zagreb, Croatia.
Bosnar M; Pharmacology In Vitro, Selvita Ltd., Prilaz baruna Filipovića 29, HR-10000 Zagreb, Croatia.
Škorić I; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10000 Zagreb, Croatia.
Barić D; Group for Computational Life Sciences, Division of Physical Chemistry, Ruđer Bošković Institute, Bijenička Cesta 54, HR-10000 Zagreb, Croatia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 28; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 28.
Typ publikacji:
Journal Article
MeSH Terms:
Butyrylcholinesterase*/metabolism
Acetylcholinesterase*/metabolism
Triazoles/pharmacology ; Triazoles/chemistry ; Molecular Docking Simulation ; Structure-Activity Relationship ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/chemistry ; Ligands
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biomimetic single Al-OH site with high acetylcholinesterase-like activity and self-defense ability for neuroprotection.
Autorzy:
Xu W; National Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, 430079, P.R. China.
Cai X; Department of Nutrition, Hygiene and Toxicology, School of Public Health, Medical College, Wuhan University of Science and Technology, Wuhan, 430065, P.R. China.
Wu Y; National Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, 430079, P.R. China.
Wen Y; National Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, 430079, P.R. China.
Su R; National Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, 430079, P.R. China.
Zhang Y; National Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, 430079, P.R. China.
Huang Y; Department of Nutrition, Hygiene and Toxicology, School of Public Health, Medical College, Wuhan University of Science and Technology, Wuhan, 430065, P.R. China.
Zheng Q; Department of Nutrition, Hygiene and Toxicology, School of Public Health, Medical College, Wuhan University of Science and Technology, Wuhan, 430065, P.R. China.
Hu L; School of Materials Science and Engineering, Wuhan Institute of Technology, Wuhan, 430205, P.R. China.
Cui X; Beijing Synchrotron Radiation Facility, Institute of High Energy Physics Department, Chinese Academy of Sciences Institution, Beijing, 100049, P.R. China.
Zheng L; Beijing Synchrotron Radiation Facility, Institute of High Energy Physics Department, Chinese Academy of Sciences Institution, Beijing, 100049, P.R. China.
Zhang S; School of Materials Science and Engineering, Peking University, Beijing, 100871, P.R. China.
Gu W; National Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, 430079, P.R. China.
Song W; State Key Laboratory of Heavy Oil Processing, College of New Energy and Materials, China University of Petroleum, Beijing, 102249, P.R. China.
Guo S; School of Materials Science and Engineering, Peking University, Beijing, 100871, P.R. China. .
Zhu C; National Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, 430079, P.R. China. .
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Źródło:
Nature communications [Nat Commun] 2023 Sep 28; Vol. 14 (1), pp. 6064. Date of Electronic Publication: 2023 Sep 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcholinesterase*/chemistry
Biomimetics*
Neuroprotection ; Organophosphates
Czasopismo naukowe
Szczegóły
Tytuł:
Study on the active ingredients of Shenghui decoction inhibiting acetylcholinesterase based on molecular docking and molecular dynamics simulation.
Autorzy:
Li Z; School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Shi H
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Źródło:
Medicine [Medicine (Baltimore)] 2023 Sep 22; Vol. 102 (38), pp. e34909.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*
Molecular Dynamics Simulation*
Humans ; Acetylcholine ; Cholinesterase Inhibitors/pharmacology ; Ligands ; Molecular Docking Simulation ; Drugs, Chinese Herbal
Czasopismo naukowe
Szczegóły
Tytuł:
Novel iodoquinazolinones bearing sulfonamide moiety as potential antioxidants and neuroprotectors.
Autorzy:
Soliman AM; Drug Chemistry Laboratory, Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, 11787, Egypt.
Ghorab WM; Drug Chemistry Laboratory, Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, 11787, Egypt.
Lotfy DM; Pharmacology and Toxicology Laboratory, Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, 11787, Egypt.
Karam HM; Pharmacology and Toxicology Laboratory, Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, 11787, Egypt.
Ghorab MM; Drug Chemistry Laboratory, Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, 11787, Egypt. .
Ramadan LA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Egyptian Russian University, Cairo-Suez Road, Badr City, Cairo, 11829, Egypt.
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 20; Vol. 13 (1), pp. 15546. Date of Electronic Publication: 2023 Sep 20.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/pharmacology
Acetylcholinesterase*
Animals ; Mice ; Molecular Docking Simulation ; Glutathione ; Sulfanilamide ; Acetamides
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Label free impedance based acetylcholinesterase enzymatic biosensors for the detection of acetylcholine.
Autorzy:
Chen J; Department of Bioengineering, University of Texas at Dallas, 800 W. Campbell Rd, Richardson, TX, 75083, USA.
Lin KC; Department of Bioengineering, University of Texas at Dallas, 800 W. Campbell Rd, Richardson, TX, 75083, USA.
Prasad S; Department of Bioengineering, University of Texas at Dallas, 800 W. Campbell Rd, Richardson, TX, 75083, USA. Electronic address: .
Schmidtke DW; Department of Bioengineering, University of Texas at Dallas, 800 W. Campbell Rd, Richardson, TX, 75083, USA. Electronic address: .
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Źródło:
Biosensors & bioelectronics [Biosens Bioelectron] 2023 Sep 01; Vol. 235, pp. 115340. Date of Electronic Publication: 2023 May 06.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/chemistry
Biosensing Techniques*/methods
Animals ; Rats ; Acetylcholine ; Electric Impedance ; Electrochemical Techniques/methods ; Microelectrodes ; Gold/chemistry
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 50322

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