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Tytuł:
AChE as a spark in the Alzheimer's blaze - Antagonizing effect of a cyclized variant.
Autorzy:
Behl T; School of Health Sciences and Technology, University of Petroleum and Energy Studies, Bidohli, Uttarakhand, India. Electronic address: .
Kaur I; University of Glasgow, College of Medical, Veterinary and Life Sciences, Glasgow, United Kingdom.
Sehgal A; GHG Khalsa College of Pharmacy, Gurusar Sadhar, Ludhiana, Punjab, India.
Singh S; MM College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, India.
Sharma N; MM College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, India.
Gupta S; MM College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, India.
Albratty M; Department of Pharmaceutical Chemistry and Pharmacognosy, College of Pharmacy, Jazan University, Jazan, Saudi Arabia.
Najmi A; Department of Pharmaceutical Chemistry and Pharmacognosy, College of Pharmacy, Jazan University, Jazan, Saudi Arabia.
Alhazmi HA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jazan University, Jazan, Saudi Arabia; Substance Abuse and Toxicology, Research Centre, Jazan University, Jazan, Saudi Arabia.
Bungau S; Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania; Doctoral School of Biomedical Sciences, University of Oradea, Oradea, Romania.
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Źródło:
Ageing research reviews [Ageing Res Rev] 2023 Jan; Vol. 83, pp. 101787. Date of Electronic Publication: 2022 Nov 08.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Acetylcholinesterase*/metabolism
Acetylcholinesterase*/therapeutic use
Alzheimer Disease*/metabolism
Humans ; Amyloid beta-Peptides/metabolism ; Glycogen Synthase Kinase 3/therapeutic use ; Neurofibrillary Tangles/pathology ; Plaque, Amyloid/pathology ; Amyloid beta-Protein Precursor/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Donepezil inhibits neuromuscular junctional acetylcholinesterase and enhances synaptic transmission and function in isolated skeletal muscle.
Autorzy:
Redman RR; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.
Mackenzie H; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.
Dissanayake KN; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.
Eddleston M; Pharmacology, Toxicology and Therapeutics, Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
Ribchester RR; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2022 Dec; Vol. 179 (24), pp. 5273-5289. Date of Electronic Publication: 2022 Sep 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcholinesterase*/metabolism
Acetylcholinesterase*/pharmacology
Neuromuscular Junction*/metabolism
Humans ; Mice ; Animals ; Donepezil/pharmacology ; Synaptic Transmission ; Muscle, Skeletal/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Genetic analyses and detection of point mutations in the acetylcholinesterase-1 gene associated with organophosphate insecticide resistance in fall armyworm (Spodoptera frugiperda) populations from Uganda.
Autorzy:
Omuut G; National Agricultural Research Organization, National Crops Resources Research Institute, P. O Box, 7084, Kampala, Uganda.
Mollel HG; Tanzania Agricultural Research Institute-Mikocheni, P. O. Box, 6226, Dar es Salaam, Tanzania.
Kanyesigye D; National Agricultural Research Organization, National Crops Resources Research Institute, P. O Box, 7084, Kampala, Uganda.
Akohoue F; Laboratory of Genetics, Biotechnology and Seed Science (GBioS), Faculty of Agronomic Sciences, University of Abomey-Calavi, Abomey-Calavi, Benin.; State Plant Breeding Institute, University of Hohenheim, 70599, Stuttgart, Germany.
Adumo Aropet S; National Agricultural Research Organization, National Agricultural Research Laboratories, P.O. Box 7065, Kampala, Uganda.
Wagaba H; National Agricultural Research Organization, National Crops Resources Research Institute, P. O Box, 7084, Kampala, Uganda.
Otim MH; National Agricultural Research Organization, National Crops Resources Research Institute, P. O Box, 7084, Kampala, Uganda. .
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Źródło:
BMC genomics [BMC Genomics] 2023 Jan 16; Vol. 24 (1), pp. 22. Date of Electronic Publication: 2023 Jan 16.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/genetics
Insecticides*/pharmacology
Animals ; Spodoptera/genetics ; Point Mutation ; Organophosphates/pharmacology ; Uganda ; Insecticide Resistance/genetics ; Zea mays/genetics ; Larva
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
New amides derived from sclareolide as anticholinesterase agents.
Autorzy:
Silva JG; Department of Chemistry, Federal University of Minas Gerais, Av. Pres. Antônio Carlos, 6627, Campus Pampulha, CEP 31270-901, Belo Horizonte, MG, Brazil. Electronic address: .
Borgati TF; Department of Chemistry, Federal University of Minas Gerais, Av. Pres. Antônio Carlos, 6627, Campus Pampulha, CEP 31270-901, Belo Horizonte, MG, Brazil; Department of Natural Sciences, State University of Minas Gerais, Av. Paraná, 3001 - Jardim Belvedere I, CEP 35501-170, Divinópolis - MG, Brazil.
Lopes SMG; Department of Chemistry, Federal University of Minas Gerais, Av. Pres. Antônio Carlos, 6627, Campus Pampulha, CEP 31270-901, Belo Horizonte, MG, Brazil.
Heise N; Martin-Luther-University Halle-Wittenberg, Organic Chemistry, Kurt-Mothes-Str. 2, D-06120 Halle (Saale), Germany.
Hoenke S; Martin-Luther-University Halle-Wittenberg, Organic Chemistry, Kurt-Mothes-Str. 2, D-06120 Halle (Saale), Germany.
Csuk R; Martin-Luther-University Halle-Wittenberg, Organic Chemistry, Kurt-Mothes-Str. 2, D-06120 Halle (Saale), Germany. Electronic address: .
Barbosa LCA; Department of Chemistry, Federal University of Minas Gerais, Av. Pres. Antônio Carlos, 6627, Campus Pampulha, CEP 31270-901, Belo Horizonte, MG, Brazil. Electronic address: .
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Źródło:
Bioorganic chemistry [Bioorg Chem] 2023 Jan; Vol. 130, pp. 106249. Date of Electronic Publication: 2022 Nov 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholinesterase Inhibitors*/pharmacology
Cholinesterase Inhibitors*/chemistry
Acetylcholinesterase*/metabolism
Mice ; Animals ; Amides/pharmacology ; Molecular Docking Simulation
Czasopismo naukowe
Szczegóły
Tytuł:
Pathology and prevention of brain microvascular and neuronal dysfunction induced by a high-fructose diet in rats.
Autorzy:
Chavushyan VA; Neuroendocrine Relationships Lab, Orbeli Institute of Physiology NAS RA, 0028, Yerevan, Armenia.
Simonyan KV; Neuroendocrine Relationships Lab, Orbeli Institute of Physiology NAS RA, 0028, Yerevan, Armenia. .
Danielyan MH; Histochemistry and Electron Microscopy Lab, Orbeli Institute of Physiology NAS RA, 0028, Yerevan, Armenia.
Avetisyan LG; Neuroendocrine Relationships Lab, Orbeli Institute of Physiology NAS RA, 0028, Yerevan, Armenia.
Darbinyan LV; Sensorimotor Integration Lab, Orbeli Institute of Physiology NAS RA, 0028, Yerevan, Armenia.
Isoyan AS; Neuroendocrine Relationships Lab, Orbeli Institute of Physiology NAS RA, 0028, Yerevan, Armenia.
Lorikyan AG; Neuroendocrine Relationships Lab, Orbeli Institute of Physiology NAS RA, 0028, Yerevan, Armenia.
Hovhannisyan LE; G.S. Davtyan Institute of Hydroponics Problems NAS RA, 0082, Yerevan, Armenia.
Babakhanyan MA; G.S. Davtyan Institute of Hydroponics Problems NAS RA, 0082, Yerevan, Armenia.
Sukiasyan LM; Neuroendocrine Relationships Lab, Orbeli Institute of Physiology NAS RA, 0028, Yerevan, Armenia.; Yerevan State Medical University After M. Heratsi, 0025, Yerevan, Armenia.
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Źródło:
Metabolic brain disease [Metab Brain Dis] 2023 Jan; Vol. 38 (1), pp. 269-286. Date of Electronic Publication: 2022 Oct 22.
Typ publikacji:
Journal Article
MeSH Terms:
Fructose*/pharmacology
Fructose*/metabolism
Acetylcholinesterase*/metabolism
Rats ; Animals ; Microcirculation ; Brain/metabolism ; Diet ; Neurons/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Design, Synthesis and Assay of Novel Methylxanthine-Alkynylmethylamine Derivatives as Acetylcholinesterase Inhibitors.
Autorzy:
Reshetnikov DV; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentyev Ave, 9, 630090 Novosibirsk, Russia.
Ivanov ID; The Federal Research Center Institute of Molecular Biology and Biophysics, Timakov Str., 2/12, 630117 Novosibirsk, Russia.
Baev DS; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentyev Ave, 9, 630090 Novosibirsk, Russia.
Rybalova TV; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentyev Ave, 9, 630090 Novosibirsk, Russia.
Mozhaitsev ES; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentyev Ave, 9, 630090 Novosibirsk, Russia.
Patrushev SS; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentyev Ave, 9, 630090 Novosibirsk, Russia.; Novosibirsk State University, Pirogova Str., 1, 630090 Novosibirsk, Russia.
Vavilin VA; The Federal Research Center Institute of Molecular Biology and Biophysics, Timakov Str., 2/12, 630117 Novosibirsk, Russia.; Novosibirsk State University, Pirogova Str., 1, 630090 Novosibirsk, Russia.
Tolstikova TG; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentyev Ave, 9, 630090 Novosibirsk, Russia.; Novosibirsk State University, Pirogova Str., 1, 630090 Novosibirsk, Russia.
Shults EE; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentyev Ave, 9, 630090 Novosibirsk, Russia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Dec 11; Vol. 27 (24). Date of Electronic Publication: 2022 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
Cholinesterase Inhibitors*/chemistry
Acetylcholinesterase*/metabolism
Molecular Docking Simulation ; Xanthines/pharmacology ; Structure-Activity Relationship ; Molecular Structure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phthalimide-tethered imidazolium salts: Synthesis, characterization, enzyme inhibitory properties, and in silico studies.
Autorzy:
Yiğit M; Department of Chemistry and Chemical Process Technologies, Vocational School of Technical Sciences, Adiyaman University, Adıyaman, Turkey.
Demir Y; Department of Pharmacy Services, Nihat Delibalta Göle Vocational High School, Ardahan University, Ardahan, Turkey.
Barut Celepci D; Department of Physics, Faculty of Science, Dokuz Eylül University, İzmir, Turkey.
Taskin-Tok T; Department of Chemistry, Faculty of Arts and Sciences, Gaziantep University, Gaziantep, Turkey.; Department of Bioinformatics and Computational Biology, Institute of Health Sciences, Gaziantep University, Gaziantep, Turkey.
Arınç A; Department of Chemistry, Faculty of Science and Art, Adiyaman University, Adıyaman, Turkey.
Yiğit B; Department of Chemistry, Faculty of Science and Art, Adiyaman University, Adıyaman, Turkey.
Aygün M; Department of Physics, Faculty of Science, Dokuz Eylül University, İzmir, Turkey.
Özdemir İ; Department of Chemistry, Faculty of Science and Art, İnönü University, Malatya, Turkey.
Gülçin İ; Department of Chemistry, Faculty of Science, Atatürk University, Erzurum, Turkey.
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Źródło:
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2022 Dec; Vol. 355 (12), pp. e2200348. Date of Electronic Publication: 2022 Sep 25.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/metabolism
Carbonic Anhydrase II*
Humans ; Carbonic Anhydrase Inhibitors ; Salts/pharmacology ; Cholinesterase Inhibitors/chemistry ; Molecular Docking Simulation ; Spectroscopy, Fourier Transform Infrared ; Structure-Activity Relationship ; Carbonic Anhydrase I ; Phthalimides/pharmacology ; Molecular Structure
Czasopismo naukowe
Szczegóły
Tytuł:
Enzyme kinetics by real-time quantitative NMR (qNMR) spectroscopy with progress curve analysis.
Autorzy:
Vang JY; Department of Chemistry & Biochemistry, California State University, Fresno, CA, 93740, USA.
Breceda C Jr; Department of Chemistry & Biochemistry, California State University, Fresno, CA, 93740, USA.
Her C; Department of Chemistry & Biochemistry, California State University, Fresno, CA, 93740, USA.
Krishnan VV; Department of Chemistry & Biochemistry, California State University, Fresno, CA, 93740, USA; Department of Medical Pathology & Laboratory Medicine, University of California Davis School of Medicine, Davis, CA, 95616, USA. Electronic address: .
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Źródło:
Analytical biochemistry [Anal Biochem] 2022 Dec 01; Vol. 658, pp. 114919. Date of Electronic Publication: 2022 Sep 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
beta-Fructofuranosidase*
Acetylcholinesterase*
Kinetics ; Lactose ; Galactose ; Acetylcholine ; Magnetic Resonance Spectroscopy ; Sucrose/chemistry ; Fructose ; beta-Galactosidase ; Glucose/chemistry ; Sweetening Agents ; Choline
Czasopismo naukowe
Szczegóły
Tytuł:
Dyhidro-β-agarofurans natural and synthetic as acetylcholinesterase and COX inhibitors: interaction with the peripheral anionic site (AChE-PAS), and anti-inflammatory potentials.
Autorzy:
Alarcón-Enos J; Departamento de Ciencias Básicas, Universidad del Bío-Bío, Chillán, Chile.
Muñoz-Núñez E; Departamento de Ciencias Básicas, Universidad del Bío-Bío, Chillán, Chile.
Gutiérrez M; Instituto de Química, Universidad de Talca, Talca, Chile.
Quiroz-Carreño S; Departamento de Ciencias Básicas, Universidad del Bío-Bío, Chillán, Chile.
Pastene-Navarrete E; Departamento de Ciencias Básicas, Universidad del Bío-Bío, Chillán, Chile.
Céspedes Acuña C; Departamento de Ciencias Básicas, Universidad del Bío-Bío, Chillán, Chile.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 1845-1856.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/metabolism
Alzheimer Disease*/drug therapy
Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Catalytic Domain ; Cholinesterase Inhibitors/chemistry ; Humans ; Molecular Docking Simulation ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Allele Specific Polymerase Chain Reaction (AS-PCR) Assay to Detect Knockdown and Acetylcholinesterase Mutations in Anopheles superpictus
Autorzy:
Yavaşoğlu Sİ; Aydın Adnan Menderes University Faculty of Science, Department of Biology, Aydın, Turkey
Şimşek FM; Aydın Adnan Menderes University Faculty of Science, Department of Biology, Aydın, Turkey
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Transliterated Title:
Anopheles superpictus ’ta Knockdown ve Asetilkolinesteraz Mutasyonlarının Belirlenmesinde Allel Spesifik Polimeraz Zincir Reaksiyonunun (AS-PCR) Kullanılması.
Źródło:
Turkiye parazitolojii dergisi [Turkiye Parazitol Derg] 2022 Nov 28; Vol. 46 (4), pp. 307-311.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/genetics
Anopheles*/genetics
Female ; Animals ; Alleles ; Mosquito Vectors ; Polymerase Chain Reaction ; Mutation
Czasopismo naukowe
Szczegóły
Tytuł:
Exploring the Inhibition of Quercetin on Acetylcholinesterase by Multispectroscopic and In Silico Approaches and Evaluation of Its Neuroprotective Effects on PC12 Cells.
Autorzy:
Liao Y; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.; School of Pharmaceutical Science, Nanchang University, Nanchang 330006, China.
Mai X; School of Pharmaceutical Science, Nanchang University, Nanchang 330006, China.
Wu X; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.; Faculty of Life Science & Medicine, Northwest University, Xi'an 710069, China.
Hu X; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Luo X; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Zhang G; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Nov 17; Vol. 27 (22). Date of Electronic Publication: 2022 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/metabolism
Neuroprotective Agents*/pharmacology
Rats ; Animals ; PC12 Cells ; Quercetin/pharmacology ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel Uracil-Based Inhibitors of Acetylcholinesterase with Potency for Treating Memory Impairment in an Animal Model of Alzheimer's Disease.
Autorzy:
Semenov VE; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, Kazan 420088, Russia.
Zueva IV; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, Kazan 420088, Russia.
Lushchekina SV; Emanuel Institute of Biochemical Physics, Kosygina st. 4, Moscow 119334, Russia.
Suleimanov EG; Alexander Butlerov Institute of Chemistry, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kremlyovskaya str. 18, Kazan 420008, Russia.
Gubaidullina LM; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, Kazan 420088, Russia.
Shulaeva MM; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, Kazan 420088, Russia.
Lenina OA; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, Kazan 420088, Russia.
Petrov KA; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, Kazan 420088, Russia.; Alexander Butlerov Institute of Chemistry, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kremlyovskaya str. 18, Kazan 420008, Russia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Nov 14; Vol. 27 (22). Date of Electronic Publication: 2022 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*
Alzheimer Disease*/drug therapy
Animals ; Memory Disorders/drug therapy ; Disease Models, Animal ; Plaque, Amyloid ; Uracil/pharmacology ; Uracil/therapeutic use ; Benzoates
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Silico Identification of Multi-Target Ligands as Promising Hit Compounds for Neurodegenerative Diseases Drug Development.
Autorzy:
Alov P; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Bl. 105, 1113 Sofia, Bulgaria.
Stoimenov H; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Bl. 105, 1113 Sofia, Bulgaria.
Lessigiarska I; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Bl. 105, 1113 Sofia, Bulgaria.
Pencheva T; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Bl. 105, 1113 Sofia, Bulgaria.
Tzvetkov NT; Institute of Molecular Biology 'Acad. Roumen Tsanev', Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Bl. 21, 1113 Sofia, Bulgaria.
Pajeva I; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Bl. 105, 1113 Sofia, Bulgaria.
Tsakovska I; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Bl. 105, 1113 Sofia, Bulgaria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 07; Vol. 23 (21). Date of Electronic Publication: 2022 Nov 07.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/metabolism
Neurodegenerative Diseases*/drug therapy
Humans ; Ligands ; Monoamine Oxidase/metabolism ; Drug Development ; Molecular Docking Simulation ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/therapeutic use ; Cholinesterase Inhibitors/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Protection of insect neurons by erythropoietin/CRLF3-mediated regulation of pro-apoptotic acetylcholinesterase.
Autorzy:
Knorr DY; Department of Cellular Neurobiology, Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, Georg-August-University Göttingen, Göttingen, Germany.
Schneider K; Department of Cellular Neurobiology, Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, Georg-August-University Göttingen, Göttingen, Germany.
Büschgens L; Department of Cellular Neurobiology, Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, Georg-August-University Göttingen, Göttingen, Germany.
Förster J; Department of Cellular Neurobiology, Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, Georg-August-University Göttingen, Göttingen, Germany.
Georges NS; Department of Cellular Neurobiology, Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, Georg-August-University Göttingen, Göttingen, Germany.
Geurten BRH; Department of Cellular Neurobiology, Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, Georg-August-University Göttingen, Göttingen, Germany.
Heinrich R; Department of Cellular Neurobiology, Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, Georg-August-University Göttingen, Göttingen, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2022 Nov 03; Vol. 12 (1), pp. 18565. Date of Electronic Publication: 2022 Nov 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcholinesterase*/genetics
Acetylcholinesterase*/metabolism
Erythropoietin*/genetics
Erythropoietin*/pharmacology
Erythropoietin*/metabolism
Animals ; Humans ; Neurons/metabolism ; Receptors, Erythropoietin/genetics ; Receptors, Erythropoietin/metabolism ; Insecta/metabolism ; Hypoxia/metabolism ; Receptors, Cytokine/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
A Sensitive and Selective Colorimetric Method Based on the Acetylcholinesterase-like Activity of Zeolitic Imidazolate Framework-8 and Its Applications.
Autorzy:
Chen GY; School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, China.
Qian ZM; College of Medical Imagine Laboratory and Rehabilitation, Xiangnan University, Chenzhou 423000, China.; Dongguan HEC Cordyceps R&D Co., Ltd., Dongguan 523850, China.
Yin SJ; School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, China.
Zhou X; School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, China.
Yang FQ; School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Nov 03; Vol. 27 (21). Date of Electronic Publication: 2022 Nov 03.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*
Zeolites*
Colorimetry ; Acetylthiocholine ; Glucose
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Aminoalkoxy-substituted coumarins: Synthesis and evaluation for reactivation of inhibited human acetylcholinesterase.
Autorzy:
Elsinghorst PW; Food Chemistry, Central Institute of the Bundeswehr Medical Service Munich, Garching, Germany.; Department of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, University of Bonn, Bonn, Germany.
Wille T; Bundeswehr Institute of Pharmacology and Toxicology, München, Germany.
Barić D; Group for Computational Life Sciences, Division of Physical Chemistry, Ruđer Bošković Institute, Zagreb, Croatia.
Mertens MD; Department of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, University of Bonn, Bonn, Germany.
Baumann M; Bundeswehr Institute of Pharmacology and Toxicology, München, Germany.
Küppers J; Department of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, University of Bonn, Bonn, Germany.; Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.
Gütschow M; Department of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, University of Bonn, Bonn, Germany.
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Źródło:
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2022 Nov; Vol. 355 (11), pp. e2200208. Date of Electronic Publication: 2022 Jul 25.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/metabolism
Cholinesterase Reactivators*/chemistry
Cholinesterase Reactivators*/pharmacology
Humans ; Cholinesterase Inhibitors/pharmacology ; Oximes/chemistry ; Structure-Activity Relationship ; Organophosphorus Compounds/pharmacology ; Coumarins/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Structural fractal analysis of the active sites of acetylcholinesterase from various organisms.
Autorzy:
Grigorev V; Department of Computer-aided Molecular Design, Institute of Physiologically Active Compounds, Russian Academy of Sciences, Severniy proezd 1, 142432, Chernogolovka, Moscow region, Russia. Electronic address: .
Tinkov O; Department of Pharmacology and Pharmaceutical Chemistry, Medical Faculty, Transnistrian State University, October 25 Str. 128, 3300, Tiraspol, Transdniestria, Republic of Moldova.
Grigoreva L; Department of Fundamental Physical and Chemical Engineering, Moscow State University, Leninskiye Gory 1/51, 119991, Moscow, Russia.
Rasdolsky A; Department of Computer-aided Molecular Design, Institute of Physiologically Active Compounds, Russian Academy of Sciences, Severniy proezd 1, 142432, Chernogolovka, Moscow region, Russia.
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Źródło:
Journal of molecular graphics & modelling [J Mol Graph Model] 2022 Nov; Vol. 116, pp. 108265. Date of Electronic Publication: 2022 Jul 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcholinesterase*/chemistry
Fractals*
Animals ; Catalytic Domain ; Cholinesterase Inhibitors/chemistry ; Cholinesterase Inhibitors/pharmacology ; Drosophila melanogaster ; Electrophorus/metabolism ; Humans ; Mice ; Torpedo/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
CoOOH nanosheets ensure ratiometric fluorescence assay of acetylcholinesterase.
Autorzy:
Zhang Wang Xu Yang Shu XP; Department of Chemistry, College of Sciences, Northeastern University, Shenyang, 110819, China. Electronic address: .
Wang JH; Department of Chemistry, College of Sciences, Northeastern University, Shenyang, 110819, China. Electronic address: .
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Źródło:
Talanta [Talanta] 2022 Nov 01; Vol. 249, pp. 123664. Date of Electronic Publication: 2022 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*
Quantum Dots*
Cobalt ; Fluorescence ; Fluorescent Dyes ; Humans ; Oxides
Czasopismo naukowe
Szczegóły
Tytuł:
Synthesis of Novel Bromophenol with Diaryl Methanes-Determination of Their Inhibition Effects on Carbonic Anhydrase and Acetylcholinesterase.
Autorzy:
Oztaskin N; Department of Chemistry, Faculty of Science, Ataturk University, Erzurum 25240, Turkey.
Goksu S; Department of Chemistry, Faculty of Science, Ataturk University, Erzurum 25240, Turkey.
Demir Y; Department of Pharmacy Services, Gole Nihat Delibalta Vocational High School, Ardahan University, Ardahan 75000, Turkey.
Maras A; Department of Chemistry, Faculty of Science, Ataturk University, Erzurum 25240, Turkey.
Gulcin İ; Department of Chemistry, Faculty of Science, Ataturk University, Erzurum 25240, Turkey.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Nov 01; Vol. 27 (21). Date of Electronic Publication: 2022 Nov 01.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/metabolism
Carbonic Anhydrases*/metabolism
Carbonic Anhydrase II ; Carbonic Anhydrase Inhibitors/pharmacology ; Methane ; Cholinesterase Inhibitors/pharmacology ; Isoenzymes/metabolism ; Structure-Activity Relationship ; Molecular Structure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Acetylcholinesterase and butyrylcholinesterase inhibitory activities of antioxidant peptides obtained from enzymatic pea protein hydrolysates and their ultrafiltration peptide fractions.
Autorzy:
Asen ND; Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Aluko RE; Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.; Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, Manitoba, Canada.
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Źródło:
Journal of food biochemistry [J Food Biochem] 2022 Nov; Vol. 46 (11), pp. e14289. Date of Electronic Publication: 2022 Jun 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcholinesterase*/metabolism
Alzheimer Disease*
Pea Proteins*/chemistry
Pea Proteins*/pharmacology
Humans ; Antioxidants/pharmacology ; Antioxidants/chemistry ; Butyrylcholinesterase/metabolism ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/chemistry ; Peptides/pharmacology ; Peptides/chemistry ; Protein Hydrolysates/pharmacology ; Protein Hydrolysates/chemistry ; Ultrafiltration
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 49143

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