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Tytuł:
Wide-field fluorescence lifetime imaging of neuron spiking and subthreshold activity in vivo.
Autorzy:
Bowman AJ; Physics Department, Stanford University, Stanford, CA 94305, USA.
Huang C; James H. Clark Center, Stanford University, Stanford, CA 94305, USA.
Schnitzer MJ; James H. Clark Center, Stanford University, Stanford, CA 94305, USA.; CNC Program, Stanford University, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Kasevich MA; Physics Department, Stanford University, Stanford, CA 94305, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Jun 23; Vol. 380 (6651), pp. 1270-1275. Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Neurons*/physiology
Optical Imaging*/methods
Action Potentials*
Fluorescent Dyes ; Microscopy, Fluorescence/methods ; Animals ; Drosophila melanogaster
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Action potential metrics and automated data analysis pipeline for cardiotoxicity testing using optically mapped hiPSC-derived 3D cardiac microtissues.
Autorzy:
Soepriatna AH; Center for Biomedical Engineering, School of Engineering, Brown University, Providence, Rhode Island, United States of America.
Navarrete-Welton A; Cardiovascular Research Center, Cardiovascular Institute, Rhode Island Hospital and Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.
Kim TY; Cardiovascular Research Center, Cardiovascular Institute, Rhode Island Hospital and Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.
Daley MC; Center for Biomedical Engineering, School of Engineering, Brown University, Providence, Rhode Island, United States of America.
Bronk P; Cardiovascular Research Center, Cardiovascular Institute, Rhode Island Hospital and Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.
Kofron CM; Center for Biomedical Engineering, School of Engineering, Brown University, Providence, Rhode Island, United States of America.
Mende U; Cardiovascular Research Center, Cardiovascular Institute, Rhode Island Hospital and Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.
Coulombe KLK; Center for Biomedical Engineering, School of Engineering, Brown University, Providence, Rhode Island, United States of America.
Choi BR; Cardiovascular Research Center, Cardiovascular Institute, Rhode Island Hospital and Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Feb 06; Vol. 18 (2), pp. e0280406. Date of Electronic Publication: 2023 Feb 06 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Action Potentials*/physiology
Cardiotoxicity*
Induced Pluripotent Stem Cells*/physiology
Humans ; Ion Channels ; Myocytes, Cardiac/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A pilot study of ion current estimation by ANN from action potential waveforms.
Autorzy:
Şengül Ayan S; Department of Engineering, Industrial Engineering, Antalya Bilim University, Döşemealtı, Antalya, Turkey. .
Süleymanoğlu S; Department of Engineering, Electrical and Computer Engineering, Antalya Bilim University, Döşemealtı, Antalya, Turkey.
Özdoğan H; Department of Medical Imaging Techniques, Vocational School of Health Services, Antalya Bilim University, Döşemealtı, Antalya, Turkey.
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Źródło:
Journal of biological physics [J Biol Phys] 2022 Dec; Vol. 48 (4), pp. 461-475. Date of Electronic Publication: 2022 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Action Potentials*
Pilot Projects ; Bayes Theorem
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dual-polarity voltage imaging of the concurrent dynamics of multiple neuron types.
Autorzy:
Kannan M; The John B. Pierce Laboratory, New Haven, CT 06519, USA.; Department of Cellular and Molecular Physiology, Yale University, New Haven, CT 06520, USA.
Vasan G; The John B. Pierce Laboratory, New Haven, CT 06519, USA.; Department of Cellular and Molecular Physiology, Yale University, New Haven, CT 06520, USA.
Haziza S; James H. Clark Center, Stanford University, Stanford, CA 94305, USA.; CNC Program, Stanford University, Stanford, CA 94305, USA.
Huang C; James H. Clark Center, Stanford University, Stanford, CA 94305, USA.
Chrapkiewicz R; James H. Clark Center, Stanford University, Stanford, CA 94305, USA.; CNC Program, Stanford University, Stanford, CA 94305, USA.
Luo J; James H. Clark Center, Stanford University, Stanford, CA 94305, USA.; CNC Program, Stanford University, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Cardin JA; Department of Neuroscience, Yale University, New Haven, CT 06520, USA.; Kavli Institute of Neuroscience, Yale University, New Haven, CT 06520, USA.; Wu Tsai Institute, Yale University, New Haven, CT 06520, USA.
Schnitzer MJ; James H. Clark Center, Stanford University, Stanford, CA 94305, USA.; CNC Program, Stanford University, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Pieribone VA; The John B. Pierce Laboratory, New Haven, CT 06519, USA.; Department of Cellular and Molecular Physiology, Yale University, New Haven, CT 06520, USA.; Department of Neuroscience, Yale University, New Haven, CT 06520, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Nov 04; Vol. 378 (6619), pp. eabm8797. Date of Electronic Publication: 2022 Nov 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Action Potentials*/physiology
Hippocampus*/cytology
Hippocampus*/physiology
Neurons*/classification
Neurons*/physiology
Molecular Imaging*/methods
Visual Cortex*/cytology
Visual Cortex*/physiology
Animals ; Mice ; Interneurons/physiology ; Vasoactive Intestinal Peptide/metabolism ; Rhodopsin/chemistry ; Rhodopsin/genetics ; Luminescent Proteins/chemistry ; Luminescent Proteins/genetics ; Fluorescence ; Luminescent Measurements
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An action potential initiation mechanism in distal axons for the control of dopamine release.
Autorzy:
Liu C; Department of Neurobiology, Harvard Medical School, Boston, MA, USA.
Cai X; Department of Neurobiology, Harvard Medical School, Boston, MA, USA.
Ritzau-Jost A; Carl-Ludwig-Institute of Physiology, Faculty of Medicine, Leipzig University, Leipzig, Germany.
Kramer PF; Cellular Neurophysiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Li Y; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing, China.
Khaliq ZM; Cellular Neurophysiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Hallermann S; Carl-Ludwig-Institute of Physiology, Faculty of Medicine, Leipzig University, Leipzig, Germany.
Kaeser PS; Department of Neurobiology, Harvard Medical School, Boston, MA, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Mar 25; Vol. 375 (6587), pp. 1378-1385. Date of Electronic Publication: 2022 Mar 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Action Potentials*
Axons*/physiology
Cholinergic Neurons*/metabolism
Corpus Striatum*/physiology
Dopamine*/metabolism
Synaptic Transmission*
Acetylcholine/metabolism ; Animals ; Mice ; Receptors, Nicotinic/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibition of the Akt/PKB Kinase Increases Na v 1.6-Mediated Currents and Neuronal Excitability in CA1 Hippocampal Pyramidal Neurons.
Autorzy:
Marosi M; Department of Pharmacology & Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Nenov MN; Department of Pharmacology & Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Di Re J; Department of Pharmacology & Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Dvorak NM; Department of Pharmacology & Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Alshammari M; Department of Pharmacology & Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.; Department of Pharmacology, College of Pharmacy, King Saud University, Riyadh P.O. Box 145111, Saudi Arabia.
Laezza F; Department of Pharmacology & Toxicology, The University of Texas Medical Branch, Galveston, TX 77555, USA.; Center for Addiction Research, Center for Biomedical Engineering and Mitchell, Center for Neurodegenerative Diseases, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Feb 01; Vol. 23 (3). Date of Electronic Publication: 2022 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Action Potentials*
Hippocampus/*drug effects
NAV1.6 Voltage-Gated Sodium Channel/*metabolism
Proto-Oncogene Proteins c-akt/*antagonists & inhibitors
Animals ; HEK293 Cells ; Hippocampus/metabolism ; Hippocampus/physiology ; Humans ; Mice ; Proto-Oncogene Proteins c-akt/metabolism ; Pyramidal Cells/drug effects ; Pyramidal Cells/metabolism ; Pyramidal Cells/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Age-related changes in Kv4/Shal and Kv1/Shaker expression in Drosophila and a role for reactive oxygen species.
Autorzy:
Vallejos MJ; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America.
Eadaim A; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America.
Hahm ET; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America.
Tsunoda S; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Dec 21; Vol. 16 (12), pp. e0261087. Date of Electronic Publication: 2021 Dec 21 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Action Potentials*
Drosophila Proteins/*metabolism
Drosophila melanogaster/*metabolism
Neurons/*physiology
Reactive Oxygen Species/*metabolism
Shaker Superfamily of Potassium Channels/*metabolism
Shal Potassium Channels/*metabolism
Age Factors ; Animals ; Drosophila Proteins/genetics ; Drosophila melanogaster/genetics ; Male ; Neurons/cytology ; Shaker Superfamily of Potassium Channels/genetics ; Shal Potassium Channels/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical Outcomes of low-voltage area-guided left atrial linear ablation for non-paroxysmal atrial fibrillation patients.
Autorzy:
Liu HT; Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.
Yang CH; Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.
Lee HL; Department of Anesthesia, Chang Gung Memorial Hospital, Taipei Branch, Taipei, Taiwan.
Chang PC; Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.
Wo HT; Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.
Wen MS; Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.; Chang Gung University College of Medicine, Taoyuan, Taiwan.
Wang CC; Department of Anesthesia, Chang Gung Memorial Hospital, Taipei Branch, Taipei, Taiwan.
Yeh SJ; Department of Anesthesia, Chang Gung Memorial Hospital, Taipei Branch, Taipei, Taiwan.
Chou CC; Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.; Chang Gung University College of Medicine, Taoyuan, Taiwan.
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Źródło:
PloS one [PLoS One] 2021 Dec 02; Vol. 16 (12), pp. e0260834. Date of Electronic Publication: 2021 Dec 02 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Action Potentials*
Atrial Remodeling*
Atrial Fibrillation/*mortality
Catheter Ablation/*mortality
Heart Atria/*physiopathology
Atrial Fibrillation/pathology ; Atrial Fibrillation/therapy ; Case-Control Studies ; Electrophysiologic Techniques, Cardiac ; Female ; Follow-Up Studies ; Heart Rate ; Humans ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Survival Rate
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Dissecting cascade computational components in spiking neural networks.
Autorzy:
Jia S; Institute for Artificial Intelligence, Department of Computer Science and Technology, Peking University, Beijing, China.
Xing D; State Key Laboratory of Cognitive Neuroscience and Learning, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Yu Z; Institute for Artificial Intelligence, Department of Computer Science and Technology, Peking University, Beijing, China.
Liu JK; School of Computing, University of Leeds, Leeds, United Kingdom.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2021 Nov 29; Vol. 17 (11), pp. e1009640. Date of Electronic Publication: 2021 Nov 29 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Action Potentials*
Models, Neurological*
Nerve Net*
Computational Biology/*methods
Neurons/*physiology
Algorithms ; Presynaptic Terminals/physiology ; Primary Visual Cortex/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Oscillatory Potentials in Achromatopsia as a Tool for Understanding Cone Retinal Functions.
Autorzy:
Righetti G; Center for Ophthalmology, University Eye Hospital, University of Tübingen, 72076 Tübingen, Germany.
Kempf M; Center for Ophthalmology, University Eye Hospital, University of Tübingen, 72076 Tübingen, Germany.; Center for Rare Eye Diseases, University of Tübingen, 72076 Tübingen, Germany.
Braun C; MEG-Center, University of Tübingen, 72076 Tübingen, Germany.; CIMeC, Center for Mind/Brain Science, University of Trento, 38123 Trento, Italy.
Jung R; Center for Ophthalmology, University Eye Hospital, University of Tübingen, 72076 Tübingen, Germany.
Kohl S; Molecular Genetics Laboratory, Center for Ophthalmology, Institute for Ophthalmic Research, University of Tübingen, 72076 Tübingen, Germany.
Wissinger B; Molecular Genetics Laboratory, Center for Ophthalmology, Institute for Ophthalmic Research, University of Tübingen, 72076 Tübingen, Germany.
Zrenner E; Center for Rare Eye Diseases, University of Tübingen, 72076 Tübingen, Germany.; Center for Ophthalmology, Institute for Ophthalmic Research, University of Tübingen, 72076 Tübingen, Germany.; Werner Reichardt Centre for Integrative Neuroscience (CIN), University of Tübingen, 72076 Tübingen, Germany.
Stingl K; Center for Ophthalmology, University Eye Hospital, University of Tübingen, 72076 Tübingen, Germany.; Center for Rare Eye Diseases, University of Tübingen, 72076 Tübingen, Germany.
Stingl K; Center for Ophthalmology, University Eye Hospital, University of Tübingen, 72076 Tübingen, Germany.; Center for Rare Eye Diseases, University of Tübingen, 72076 Tübingen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 24; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 24.
Typ publikacji:
Journal Article
MeSH Terms:
Action Potentials*
Color Vision Defects/*pathology
Electroretinography/*methods
Retinal Cone Photoreceptor Cells/*pathology
Retinal Rod Photoreceptor Cells/*pathology
Adult ; Case-Control Studies ; Female ; Humans ; Male ; Photic Stimulation
SCR Disease Name:
Achromatopsia 3
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Memories in a network with excitatory and inhibitory plasticity are encoded in the spiking irregularity.
Autorzy:
Gallinaro JV; Bioengineering Department, Imperial College London, London, United Kingdom.
Clopath C; Bioengineering Department, Imperial College London, London, United Kingdom.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2021 Nov 11; Vol. 17 (11), pp. e1009593. Date of Electronic Publication: 2021 Nov 11 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Action Potentials*
Memory*
Animals ; Models, Neurological ; Neural Inhibition/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A mathematical model of hiPSC cardiomyocytes electromechanics.
Autorzy:
Forouzandehmehr M; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Koivumäki JT; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Hyttinen J; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Paci M; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
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Źródło:
Physiological reports [Physiol Rep] 2021 Nov; Vol. 9 (22), pp. e15124.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Action Potentials/*physiology
Electrophysiological Phenomena/*physiology
Induced Pluripotent Stem Cells/*physiology
Myocardial Contraction/*physiology
Myocytes, Cardiac/*physiology
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester/pharmacology ; Action Potentials/drug effects ; Calcium Channel Agonists/pharmacology ; Calcium Channel Blockers/pharmacology ; Computer Simulation ; Electrophysiological Phenomena/drug effects ; Humans ; Models, Theoretical ; Myocardial Contraction/drug effects ; Myocytes, Cardiac/drug effects ; Verapamil/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Acute effects of cardiac contractility modulation on human induced pluripotent stem cell-derived cardiomyocytes.
Autorzy:
Feaster TK; Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, USA.
Casciola M; Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, USA.
Narkar A; Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, USA.
Blinova K; Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, USA.
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Źródło:
Physiological reports [Physiol Rep] 2021 Nov; Vol. 9 (21), pp. e15085.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Action Potentials*
Myocardial Contraction*
Induced Pluripotent Stem Cells/*cytology
Myocytes, Cardiac/*physiology
Calcium Signaling ; Cell Differentiation ; Cells, Cultured ; Humans ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Macrophage-Dependent Interleukin-6-Production and Inhibition of I K Contributes to Acquired QT Prolongation in Lipotoxic Guinea Pig Heart.
Autorzy:
Chowdhury MKH; Nora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI), University of Utah, Salt Lake City, UT 84112, USA.
Martinez-Mateu L; Signal Theory, Communications, Telematic Systems and Computation Department, Telecommunications Engineers School, King Juan Carlos University, 28942 Madrid, Spain.
Do J; Masonic Medical Research Institute, Utica, NY 13501, USA.
Aromolaran KA; Nora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI), University of Utah, Salt Lake City, UT 84112, USA.
Saiz J; Centro de Investigación e Innovación en Bioingeniería, Universitat Politècnica de València, 46022 Valencia, Spain.
Aromolaran AS; Nora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI), University of Utah, Salt Lake City, UT 84112, USA.; Masonic Medical Research Institute, Utica, NY 13501, USA.; Division of Cardiothoracic Surgery & Molecular Medicine Program, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 18; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 18.
Typ publikacji:
Journal Article
MeSH Terms:
Action Potentials*
Arrhythmias, Cardiac/*pathology
Interleukin-6/*metabolism
Long QT Syndrome/*pathology
Macrophages/*metabolism
Myocytes, Cardiac/*pathology
Potassium Channels/*chemistry
Animals ; Arrhythmias, Cardiac/metabolism ; Cardiotoxicity/physiopathology ; Female ; Guinea Pigs ; Ion Channel Gating ; Lipid Metabolism ; Long QT Syndrome/metabolism ; Myocytes, Cardiac/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cerebellar complex spikes multiplex complementary behavioral information.
Autorzy:
Markanday A; Hertie Institute for Clinical Brain Research, Tübingen, Germany.; Graduate School of Neural and Behavioral Sciences, International Max Planck Research School, Tübingen University, Tübingen, Germany.
Inoue J; Graduate School of Neural and Behavioral Sciences, International Max Planck Research School, Tübingen University, Tübingen, Germany.; Werner Reichardt Centre for Integrative Neuroscience, Tübingen University, Tübingen, Germany.
Dicke PW; Hertie Institute for Clinical Brain Research, Tübingen, Germany.
Thier P; Hertie Institute for Clinical Brain Research, Tübingen, Germany.; Werner Reichardt Centre for Integrative Neuroscience, Tübingen University, Tübingen, Germany.
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Źródło:
PLoS biology [PLoS Biol] 2021 Sep 16; Vol. 19 (9), pp. e3001400. Date of Electronic Publication: 2021 Sep 16 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Action Potentials*
Saccades*
Purkinje Cells/*physiology
Animals ; Macaca mulatta ; Male ; Movement
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Electrical properties and synaptic transmission in mouse intracardiac ganglion neurons in situ.
Autorzy:
Harper AA; Illawarra Health and Medical Research Institute (IHMRI), University of Wollongong, Wollongong, New South Wales, Australia.
Adams DJ; Illawarra Health and Medical Research Institute (IHMRI), University of Wollongong, Wollongong, New South Wales, Australia.
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Źródło:
Physiological reports [Physiol Rep] 2021 Sep; Vol. 9 (18), pp. e15056.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Action Potentials*
Synaptic Transmission*
Heart/*innervation
Neurons/*physiology
Vagus Nerve/*physiology
Animals ; Cadmium/pharmacology ; Conotoxins/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Neurons/drug effects ; Neurons/metabolism ; Nicotinic Antagonists/pharmacology ; Vagus Nerve/cytology ; Vagus Nerve/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Na V 1.5 knockout in iPSCs: a novel approach to study Na V 1.5 variants in a human cardiomyocyte environment.
Autorzy:
Pierre M; CERVO Brain Research Center, 2601, de La Canardière, Quebec City, QC, G1J 2G3, Canada.
Djemai M; CERVO Brain Research Center, 2601, de La Canardière, Quebec City, QC, G1J 2G3, Canada.
Poulin H; CERVO Brain Research Center, 2601, de La Canardière, Quebec City, QC, G1J 2G3, Canada.
Chahine M; CERVO Brain Research Center, 2601, de La Canardière, Quebec City, QC, G1J 2G3, Canada. .; Department of Medicine, Faculty of Medicine, Université Laval, Quebec City, QC, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2021 Aug 25; Vol. 11 (1), pp. 17168. Date of Electronic Publication: 2021 Aug 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Action Potentials*
Induced Pluripotent Stem Cells/*metabolism
Long QT Syndrome/*genetics
Myocytes, Cardiac/*metabolism
NAV1.5 Voltage-Gated Sodium Channel/*genetics
Calcium Signaling ; Cell Differentiation ; Cell Line ; Gene Knockout Techniques/methods ; Homozygote ; Humans ; Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/physiology ; Mutation ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/physiology ; NAV1.5 Voltage-Gated Sodium Channel/metabolism ; Patch-Clamp Techniques/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The development of L-type Ca current mediated alternans does not depend on the restitution slope in canine ventricular myocardium.
Autorzy:
Tóth N; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Dóm tér 12, P.O. Box 427, 6720, Szeged, Hungary.
Szlovák J; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Dóm tér 12, P.O. Box 427, 6720, Szeged, Hungary.
Kohajda Z; ELKH-SZTE Research Group of Cardiovascular Pharmacology, Szeged, Hungary.
Bitay G; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Dóm tér 12, P.O. Box 427, 6720, Szeged, Hungary.
Veress R; Department of Physiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Horváth B; Department of Physiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.; Faculty of Pharmacy, University of Debrecen, Debrecen, Hungary.
Papp JG; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Dóm tér 12, P.O. Box 427, 6720, Szeged, Hungary.; ELKH-SZTE Research Group of Cardiovascular Pharmacology, Szeged, Hungary.
Varró A; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Dóm tér 12, P.O. Box 427, 6720, Szeged, Hungary.; ELKH-SZTE Research Group of Cardiovascular Pharmacology, Szeged, Hungary.; Department of Pharmacology and Pharmacotherapy, Interdisciplinary Excellence Centre, University of Szeged, Szeged, Hungary.
Nagy N; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Dóm tér 12, P.O. Box 427, 6720, Szeged, Hungary. .; ELKH-SZTE Research Group of Cardiovascular Pharmacology, Szeged, Hungary. .
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Źródło:
Scientific reports [Sci Rep] 2021 Aug 17; Vol. 11 (1), pp. 16652. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Action Potentials*
Calcium/*metabolism
Heart Ventricles/*physiopathology
Ventricular Fibrillation/*physiopathology
Animals ; Calcium Signaling ; Dogs ; Female ; Heart Ventricles/metabolism ; Heart Ventricles/pathology ; Male ; Myocardium/pathology ; Ventricular Fibrillation/metabolism ; Ventricular Fibrillation/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Modulation of the Cardiac Myocyte Action Potential by the Magnesium-Sensitive TRPM6 and TRPM7-like Current.
Autorzy:
Gwanyanya A; Department of Cardiovascular Sciences, KU Leuven, 3000 Leuven, Belgium.; Department of Human Biology, University of Cape Town, Cape Town 7925, South Africa.
Andriulė I; Institute of Cardiology, Lithuanian University of Health Sciences, 50103 Kaunas, Lithuania.
Istrate BM; Department of Cardiovascular Sciences, KU Leuven, 3000 Leuven, Belgium.
Easmin F; Department of Cardiovascular Sciences, KU Leuven, 3000 Leuven, Belgium.
Mubagwa K; Department of Cardiovascular Sciences, KU Leuven, 3000 Leuven, Belgium.; Department of Basic Sciences, Faculty of Medicine, Université Catholique de Bukavu, Bukavu, Congo.
Mačianskienė R; Institute of Cardiology, Lithuanian University of Health Sciences, 50103 Kaunas, Lithuania.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 14; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 14.
Typ publikacji:
Journal Article
MeSH Terms:
Action Potentials*
Magnesium/*metabolism
Myocytes, Cardiac/*metabolism
TRPM Cation Channels/*metabolism
Animals ; Cations, Divalent ; Myocytes, Cardiac/physiology ; Sus scrofa/metabolism ; Sus scrofa/physiology ; TRPM Cation Channels/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The neuronal potassium current I A is a potential target for pain during chronic inflammation.
Autorzy:
Biet M; Département de Pharmacologie et Physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec, Canada.
Dansereau MA; Département de Pharmacologie et Physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec, Canada.
Sarret P; Département de Pharmacologie et Physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec, Canada.
Dumaine R; Département de Pharmacologie et Physiologie, Institut de pharmacologie de Sherbrooke, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec, Canada.
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Źródło:
Physiological reports [Physiol Rep] 2021 Aug; Vol. 9 (16), pp. e14975.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Action Potentials*
Neurons, Afferent/*metabolism
Nociceptive Pain/*metabolism
Potassium Channels, Voltage-Gated/*metabolism
Animals ; Calcium Channels, L-Type/metabolism ; Cells, Cultured ; Ganglia, Spinal/cytology ; Ganglia, Spinal/metabolism ; Ganglia, Spinal/physiology ; Male ; Neurons, Afferent/drug effects ; Neurons, Afferent/physiology ; Nociception ; Nociceptive Pain/physiopathology ; Rats ; Rats, Sprague-Dawley ; Sodium Channel Blockers/pharmacology ; Sodium Channels/metabolism ; Tetrodotoxin/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 13967

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