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Tytuł:
Deep learning assists in acute leukemia detection and cell classification via flow cytometry using the acute leukemia orientation tube.
Autorzy:
Cheng FM; Division of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, 404, Taiwan.
Lo SC; Artificial Intelligence Center, China Medical University Hospital, China Medical University, Taichung, 404, Taiwan.
Lin CC; Division of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, 404, Taiwan.
Lo WJ; Division of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, 404, Taiwan.
Chien SY; Artificial Intelligence Center, China Medical University Hospital, China Medical University, Taichung, 404, Taiwan.
Sun TH; Artificial Intelligence Center, China Medical University Hospital, China Medical University, Taichung, 404, Taiwan.
Hsu KC; Artificial Intelligence Center, China Medical University Hospital, China Medical University, Taichung, 404, Taiwan. .; School of Medicine, China Medical University, Taichung, 404, Taiwan. .; Neuroscience and Brain Disease Center, China Medical University, Taichung, 404, Taiwan. .; Department of Neurology, China Medical University Hospital, China Medical University, Taichung, 404, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2024 Apr 09; Vol. 14 (1), pp. 8350. Date of Electronic Publication: 2024 Apr 09.
Typ publikacji:
Journal Article
MeSH Terms:
Deep Learning*
Leukemia, Myeloid, Acute*/diagnosis
Leukemia, Myeloid, Acute*/pathology
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/pathology
Humans ; Retrospective Studies ; Flow Cytometry/methods ; Artificial Intelligence ; Acute Disease ; Immunophenotyping
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Clinico-hematological and immunophenotypic profile of acute leukemia of ambiguous lineage: A four year experience from a single tertiary care centre of West India.
Autorzy:
Rai V; Oncopathology Department, Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India.
Brahmbhatt B; Oncopathology Department, Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India.
Saha A; Oncopathology Department, Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India.
Thayakaran IP; Oncopathology Department, Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India.
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Źródło:
Indian journal of pathology & microbiology [Indian J Pathol Microbiol] 2024 Jan-Mar; Vol. 67 (1), pp. 121-127.
Typ publikacji:
Observational Study; Journal Article
MeSH Terms:
Leukemia, Biphenotypic, Acute*/diagnosis
Leukemia, Biphenotypic, Acute*/genetics
Leukemia, Biphenotypic, Acute*/therapy
Leukemia, Myeloid, Acute*
Adult ; Child ; Female ; Humans ; Male ; Young Adult ; Acute Disease ; Immunophenotyping ; Prognosis ; Tertiary Care Centers ; Child, Preschool ; Adolescent ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Establishment and validation of prognostic nomogram in acute leukemia with trisomy 8.
Autorzy:
Deng T; Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, People's Republic of China.
Wang S; Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, People's Republic of China.
Ran Z; Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, People's Republic of China.
Liu Q; Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, People's Republic of China.
Wang M; Department of Hematology, Three Gorges Hospital Affiliated to Chongqing University, Chongqing, People's Republic of China.
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Źródło:
Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2240131.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Nomograms*
Leukemia, Myeloid, Acute*/diagnosis
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/therapy
Humans ; Middle Aged ; Prognosis ; Retrospective Studies ; Acute Disease
SCR Disease Name:
Chromosome 8, trisomy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intensified conditioning regimen with fludarabine combined with post-transplantation cyclophosphamide for haploidentical allogeneic hematopoietic stem cell transplantation in children with high-risk acute leukemia.
Autorzy:
Cao J; Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, People's Republic of China.; Institute of Hematology, Ningbo University, Ningbo, People's Republic of China.
Xu X; Department of Oncology, The First Affiliated Hospital of Ningbo University, Ningbo, People's Republic of China.
Lu Y; Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, People's Republic of China.; Institute of Hematology, Ningbo University, Ningbo, People's Republic of China.
Wang T; Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, People's Republic of China.; Institute of Hematology, Ningbo University, Ningbo, People's Republic of China.
Chen D; Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, People's Republic of China.; Institute of Hematology, Ningbo University, Ningbo, People's Republic of China.
Li S; Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, People's Republic of China.; Institute of Hematology, Ningbo University, Ningbo, People's Republic of China.
Liu X; Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, People's Republic of China.; Institute of Hematology, Ningbo University, Ningbo, People's Republic of China.
Ye P; Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, People's Republic of China.; Institute of Hematology, Ningbo University, Ningbo, People's Republic of China.
Zheng ZZ; Shanghai Tissuebank Biotechnology Co., Ltd., Shanghai, People's Republic of China.
Pei R; Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, People's Republic of China.; Institute of Hematology, Ningbo University, Ningbo, People's Republic of China.
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Źródło:
Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2223873.
Typ publikacji:
Journal Article
MeSH Terms:
Hematopoietic Stem Cell Transplantation*
Leukemia, Myeloid, Acute*/drug therapy
Graft vs Host Disease*/etiology
Graft vs Host Disease*/prevention & control
Hematologic Neoplasms*/therapy
Adult ; Humans ; Child ; Cyclophosphamide/therapeutic use ; Busulfan/therapeutic use ; Antilymphocyte Serum/therapeutic use ; Acute Disease ; Transplantation Conditioning ; Cytarabine/therapeutic use ; Recurrence ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Higher cyclosporine-A concentration increases the risk of relapse in AML following allogeneic stem cell transplantation from unrelated donors using anti-thymocyte globulin.
Autorzy:
Lisak M; Department of Hematology and Coagulation, Sahlgrenska University Hospital, Bruna stråket 5, plan 5, 413 45, Gothenburg, Sweden. .; Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden. .
Nicklasson M; Department of Hematology and Coagulation, Sahlgrenska University Hospital, Bruna stråket 5, plan 5, 413 45, Gothenburg, Sweden.
Palmason R; Department of Hematology, Skane University Hospital, Lund, Sweden.
Wichert S; Department of Hematology, Skane University Hospital, Lund, Sweden.
Isaksson C; Department of Hematology, Norrland University Hospital, Umeå, Sweden.
Andersson PO; Department of Hematology and Coagulation, Sahlgrenska University Hospital, Bruna stråket 5, plan 5, 413 45, Gothenburg, Sweden.; Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.
Johansson JE; Department of Hematology and Coagulation, Sahlgrenska University Hospital, Bruna stråket 5, plan 5, 413 45, Gothenburg, Sweden.; Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.
Lenhoff S; Department of Hematology, Skane University Hospital, Lund, Sweden.
Brune M; Department of Hematology and Coagulation, Sahlgrenska University Hospital, Bruna stråket 5, plan 5, 413 45, Gothenburg, Sweden.; Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.
Hansson M; Department of Hematology and Coagulation, Sahlgrenska University Hospital, Bruna stråket 5, plan 5, 413 45, Gothenburg, Sweden.; Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.; Department of Hematology, Skane University Hospital, Lund, Sweden.
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 20; Vol. 13 (1), pp. 22777. Date of Electronic Publication: 2023 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
Hematopoietic Stem Cell Transplantation*/adverse effects
Hematopoietic Stem Cell Transplantation*/methods
Leukemia, Myeloid, Acute*/therapy
Graft vs Host Disease*/etiology
Graft vs Host Disease*/prevention & control
Graft vs Host Disease*/epidemiology
Humans ; Cyclosporine/therapeutic use ; Antilymphocyte Serum/therapeutic use ; Unrelated Donors ; Acute Disease ; Recurrence ; Retrospective Studies ; Transplantation Conditioning/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia.
Autorzy:
Mumme HL; Aflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA.; Department of Biomedical Informatics, Emory University, Atlanta, GA, USA.
Raikar SS; Aflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA.; Department of Pediatrics, Emory University, Atlanta, GA, USA.
Bhasin SS; Aflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA.; Department of Pediatrics, Emory University, Atlanta, GA, USA.
Thomas BE; Aflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA.; Department of Pediatrics, Emory University, Atlanta, GA, USA.
Lawrence T; Aflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA.
Weinzierl EP; Department of Pathology and Laboratory Medicine, Children's Healthcare of Atlanta, Atlanta, GA, USA.
Pang Y; Department: Pediatrics - Hematology/Oncology, Stanford University, Stanford, CA, USA.
DeRyckere D; Aflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA.; Department of Pediatrics, Emory University, Atlanta, GA, USA.
Gawad C; Department: Pediatrics - Hematology/Oncology, Stanford University, Stanford, CA, USA.
Wechsler DS; Aflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA.; Department of Pediatrics, Emory University, Atlanta, GA, USA.
Porter CC; Aflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA.; Department of Pediatrics, Emory University, Atlanta, GA, USA.
Castellino SM; Aflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA.; Department of Pediatrics, Emory University, Atlanta, GA, USA.
Graham DK; Aflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA.; Department of Pediatrics, Emory University, Atlanta, GA, USA.
Bhasin M; Aflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA. .; Department of Biomedical Informatics, Emory University, Atlanta, GA, USA. .; Department of Pediatrics, Emory University, Atlanta, GA, USA. .
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Źródło:
Genome medicine [Genome Med] 2023 Oct 16; Vol. 15 (1), pp. 83. Date of Electronic Publication: 2023 Oct 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/diagnosis
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/pathology
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/diagnosis
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/pathology
Adult ; Humans ; Child ; Acute Disease ; Phenotype ; Sequence Analysis, RNA ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Influencing factors of anthracycline-induced subclinical cardiotoxicity in acute leukemia patients.
Autorzy:
Zhou X; Department of Hematopathology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China.
Weng Y; Department of Hematopathology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China.
Jiang T; Department of Hematopathology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China.
Ou W; Department of Hematopathology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China.
Zhang N; Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China.
Dong Q; Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China. .
Tang X; Department of Hematopathology, The First Affiliated Hospital of Chongqing Medical University, Yuzhong, Chongqing, China. .
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Źródło:
BMC cancer [BMC Cancer] 2023 Oct 13; Vol. 23 (1), pp. 976. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:
Observational Study; Journal Article
MeSH Terms:
Anthracyclines*/adverse effects
Leukemia, Myeloid, Acute*/drug therapy
Humans ; Acute Disease ; Antibiotics, Antineoplastic/adverse effects ; Bilirubin ; Biomarkers ; Cardiotoxicity/etiology ; Prospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Etiology and Factors Affecting Severe Complications and Mortality of Febrile Neutropenia in Children with Acute Leukemia
Autorzy:
Erbaş İC; Dokuz Eylül University Faculty of Medicine, Division of Pediatric Infectious Diseases, İzmir, Türkiye
Çakıl Güzin A; Dokuz Eylül University Faculty of Medicine, Division of Pediatric Infectious Diseases, İzmir, Türkiye
Özdem Alataş Ş; Dokuz Eylül University Faculty of Medicine, Division of Pediatric Infectious Diseases, İzmir, Türkiye
Karaoğlu Asrak H; Dokuz Eylül University Faculty of Medicine, Division of Pediatric Infectious Diseases, İzmir, Türkiye
Akans İ; Dokuz Eylül University Faculty of Medicine, Department of Pediatrics, İzmir, Türkiye
Akyol Ş; Dokuz Eylül University Faculty of Medicine, Division of Pediatric Hematology and Oncology, İzmir, Türkiye
Özlü C; Dokuz Eylül University Faculty of Medicine, Division of Pediatric Infectious Diseases, İzmir, Türkiye
Tüfekçi Ö; Dokuz Eylül University Faculty of Medicine, Division of Pediatric Hematology and Oncology, İzmir, Türkiye
Yılmaz Ş; Dokuz Eylül University Faculty of Medicine, Division of Pediatric Hematology and Oncology, İzmir, Türkiye
Ören H; Dokuz Eylül University Faculty of Medicine, Division of Pediatric Hematology and Oncology, İzmir, Türkiye
Belet N; Dokuz Eylül University Faculty of Medicine, Division of Pediatric Infectious Diseases, İzmir, Türkiye
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Źródło:
Turkish journal of haematology : official journal of Turkish Society of Haematology [Turk J Haematol] 2023 Aug 31; Vol. 40 (3), pp. 143-153. Date of Electronic Publication: 2023 Aug 01.
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, Myeloid, Acute*/complications
Leukemia, Myeloid, Acute*/drug therapy
Febrile Neutropenia*/etiology
Febrile Neutropenia*/complications
Child ; Humans ; Male ; Child, Preschool ; Female ; Retrospective Studies ; Acute Disease ; Risk Factors ; Anti-Bacterial Agents/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Landscape of FLT3 Variations Associated with Structural and Functional Impact on Acute Myeloid Leukemia: A Computational Study.
Autorzy:
Mirza Z; King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Al-Saedi DA; Department of Biochemistry, Faculty of Sciences, University of Tabuk, Tabuk 48322, Saudi Arabia.
Alganmi N; Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Computer Science Department, Faculty of Computing and Information Technology, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Karim S; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 18; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 18.
Typ publikacji:
Journal Article
MeSH Terms:
fms-Like Tyrosine Kinase 3*/genetics
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/metabolism
Humans ; Molecular Docking Simulation ; Sorafenib/pharmacology ; Mutation ; Protein-Tyrosine Kinases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Differential Gene Regulatory Network Analysis between Azacitidine-Sensitive and -Resistant Cell Lines.
Autorzy:
Park H; School of Mathematics, Statistics and Data Science, Sungshin Women's University, Seoul 02844, Republic of Korea.
Miyano S; M&D Data Science Center, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.; Human Genome Center, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokane-dai, Minato-ku, Tokyo 108-8639, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 14; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/metabolism
Neuropeptides*/metabolism
Humans ; Azacitidine/pharmacology ; Azacitidine/therapeutic use ; Gene Regulatory Networks ; Cell Line, Tumor ; Metallothionein/genetics ; Metallothionein/metabolism ; GPI-Linked Proteins/metabolism ; RNA-Binding Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Organomegalies as a predictive indicator of leukemia cutis in patients with acute myeloid leukemia.
Autorzy:
Kanitthamniyom C; Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Wannaphut C; Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
Pattanaprichakul P; Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kungwankiattichi S; Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.; Center of Excellence of Siriraj Adult Acute Myeloid/Lymphoblastic Leukemia (SiAML), Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Owattanapanich W; Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.; Center of Excellence of Siriraj Adult Acute Myeloid/Lymphoblastic Leukemia (SiAML), Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
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Źródło:
PloS one [PLoS One] 2024 Feb 16; Vol. 19 (2), pp. e0297805. Date of Electronic Publication: 2024 Feb 16 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, Myeloid, Acute*/complications
Leukemia, Myeloid, Acute*/diagnosis
Leukemia, Myeloid, Acute*/pathology
Skin Neoplasms*/complications
Leukemia, Monocytic, Acute*
Female ; Humans ; Adult ; Middle Aged ; Aged ; Retrospective Studies ; Case-Control Studies ; Recurrence ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Roles of Glutathione and AP-1 in the Enhancement of Vitamin D-Induced Differentiation by Activators of the Nrf2 Signaling Pathway in Acute Myeloid Leukemia Cells.
Autorzy:
Jramne-Saleem Y; Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 8410501, Israel.
Danilenko M; Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 8410501, Israel.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 14; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Transcription Factor AP-1*/metabolism
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/metabolism
Abietanes*
Humans ; NF-E2-Related Factor 2/metabolism ; Antioxidants/pharmacology ; Vitamin D/therapeutic use ; Vitamins/pharmacology ; Receptors, Calcitriol/metabolism ; Cell Differentiation ; Signal Transduction ; Glutathione/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dismal outcome of refractory or relapsing patients with myelodysplasia-related acute myeloid leukemia partially alleviated by intensive chemotherapy.
Autorzy:
Leroy H; CHU Bordeaux, Service d'Hématologie Clinique et de Thérapie Cellulaire, Bordeaux, France.
Gadaud N; Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
Bérard E; Centre Hospitalier Universitaire de Toulouse, Service d'Epidémiologie, CERPOP, Inserm, Université Toulouse III Paul Sabatier, Toulouse, France.
Klein E; CHU Bordeaux, Laboratoire d'Hématologie Biologique, Bordeaux, France.
Luquet I; Laboratoire d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
Vial JP; CHU Bordeaux, Laboratoire d'Hématologie Biologique, Bordeaux, France.
Rieu JB; Laboratoire d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
Lechevalier N; CHU Bordeaux, Laboratoire d'Hématologie Biologique, Bordeaux, France.
Tavitian S; Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
Leguay T; CHU Bordeaux, Service d'Hématologie Clinique et de Thérapie Cellulaire, Bordeaux, France.
Largeaud L; Laboratoire d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
Bidet A; CHU Bordeaux, Laboratoire d'Hématologie Biologique, Bordeaux, France.
Delabesse E; Laboratoire d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
Sarry A; Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
de Grande AC; CHU Bordeaux, Service d'Hématologie Clinique et de Thérapie Cellulaire, Bordeaux, France.
Récher C; Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
Pigneux A; CHU Bordeaux, Service d'Hématologie Clinique et de Thérapie Cellulaire, Bordeaux, France.; Université de Bordeaux, Bordeaux, Institut National de la Santé et de la Recherche Médicale, Bordeaux, France.
Bertoli S; Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
Dumas PY; CHU Bordeaux, Service d'Hématologie Clinique et de Thérapie Cellulaire, Bordeaux, France.; Université de Bordeaux, Bordeaux, Institut National de la Santé et de la Recherche Médicale, Bordeaux, France.
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Źródło:
Cancer medicine [Cancer Med] 2024 Feb; Vol. 13 (3), pp. e7003.
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, Myeloid, Acute*/complications
Leukemia, Myeloid, Acute*/drug therapy
Myelodysplastic Syndromes*/complications
Myelodysplastic Syndromes*/drug therapy
Humans ; Middle Aged ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Azacitidine/therapeutic use ; Recurrence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
C/EBPα-p30 confers AML cell susceptibility to the terminal unfolded protein response and resistance to Venetoclax by activating DDIT3 transcription.
Autorzy:
Du M; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Rd., Hangzhou, 310003, Zhejiang Province, People's Republic of China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China.
Wang M; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Rd., Hangzhou, 310003, Zhejiang Province, People's Republic of China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China.
Liu M; Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, USA.
Fu S; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Rd., Hangzhou, 310003, Zhejiang Province, People's Republic of China.
Lin Y; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Rd., Hangzhou, 310003, Zhejiang Province, People's Republic of China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China.
Huo Y; Hematology Department, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Dong Rd., Zhengzhou, 450000, Henan Province, People's Republic of China.
Yu J; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Rd., Hangzhou, 310003, Zhejiang Province, People's Republic of China.; Institute of Hematology, Zhejiang University, Hangzhou, China.
Yu X; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China.
Wang C; Hematology Department, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Dong Rd., Zhengzhou, 450000, Henan Province, People's Republic of China. .
Xiao H; Department of Hematology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. .; Institute of Hematology, Zhejiang University, Hangzhou, China. .; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China. .
Wang L; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Rd., Hangzhou, 310003, Zhejiang Province, People's Republic of China. .; Institute of Hematology, Zhejiang University, Hangzhou, China. .; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Mar 13; Vol. 43 (1), pp. 79. Date of Electronic Publication: 2024 Mar 13.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/therapeutic use
Bridged Bicyclo Compounds, Heterocyclic*
Leukemia, Myeloid, Acute*/metabolism
Sulfonamides*
Animals ; Humans ; Mice ; CCAAT-Enhancer-Binding Protein-alpha/genetics ; CCAAT-Enhancer-Binding Protein-alpha/metabolism ; CCAAT-Enhancer-Binding Protein-alpha/therapeutic use ; Protein Isoforms ; Proto-Oncogene Proteins c-bcl-2/genetics ; Transcription Factor CHOP/genetics ; Unfolded Protein Response
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Study of the intestinal microbiota composition and the effect of treatment with intensive chemotherapy in patients recovered from acute leukemia.
Autorzy:
Vázquez X; Dairy Research Institute of Asturias (IPLA), Spanish National Research Council, (CSIC), Villaviciosa, Asturias, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), MicroHealth Group, Oviedo, Spain.
Lumbreras-Iglesias P; Traslational Microbiology Group, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.; Department of Clinical Microbiology, Hospital Universitario Central de Asturias (HUCA), Oviedo, Spain.; Department of Hematology Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto de Oncología del Principado de Asturias (IUOPA), Hospital Universitario Central de Asturias (HUCA), 33011, Oviedo, Spain.
Rodicio MR; Traslational Microbiology Group, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.; Department of Functional Biology, Microbiology Area, University of Oviedo, Oviedo, Spain.
Fernández J; Traslational Microbiology Group, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.; Department of Clinical Microbiology, Hospital Universitario Central de Asturias (HUCA), Oviedo, Spain.; Research & Innovation, Artificial Intelligence and Statistical Department, Pragmatech AI Solutions, Oviedo, Spain.; Centro de Investigación Biomédica en Red-Enfermedades Respiratorias, Madrid, Spain.
Bernal T; Department of Hematology Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto de Oncología del Principado de Asturias (IUOPA), Hospital Universitario Central de Asturias (HUCA), 33011, Oviedo, Spain.
Moreno AF; Department of Hematology Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto de Oncología del Principado de Asturias (IUOPA), Hospital Universitario Central de Asturias (HUCA), 33011, Oviedo, Spain.
de Ugarriza PL; Department of Hematology Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto de Oncología del Principado de Asturias (IUOPA), Hospital Universitario Central de Asturias (HUCA), 33011, Oviedo, Spain.
Fernández-Verdugo A; Traslational Microbiology Group, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.; Department of Clinical Microbiology, Hospital Universitario Central de Asturias (HUCA), Oviedo, Spain.
Margolles A; Dairy Research Institute of Asturias (IPLA), Spanish National Research Council, (CSIC), Villaviciosa, Asturias, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), MicroHealth Group, Oviedo, Spain.
Sabater C; Dairy Research Institute of Asturias (IPLA), Spanish National Research Council, (CSIC), Villaviciosa, Asturias, Spain. .; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), MicroHealth Group, Oviedo, Spain. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 07; Vol. 14 (1), pp. 5585. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article
MeSH Terms:
Gastrointestinal Microbiome*/genetics
Microbiota*
Leukemia, Myeloid, Acute*
Humans ; Feces/microbiology ; Bacteria/genetics ; Bacteroidetes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of clinical outcomes of several risk stratification tools in newly diagnosed AML patients: A real-world evidence in our current therapeutic era.
Autorzy:
Iat A; Hematology department, Nice University Hospital, Nice, France.
Loschi M; Hematology department, Nice University Hospital, Nice, France.; Mediterranean Center of Molecular Medecine, INSERM, Nice, France.; Cote d'Azur University, Nice, France.
Benachour S; Hematology department, Nice University Hospital, Nice, France.
Calleja A; Hematology department, Nice University Hospital, Nice, France.
Chiche E; Hematology department, Nice University Hospital, Nice, France.; Cote d'Azur University, Nice, France.
Sudaka I; Hematology Laboratory, Nice University Hospital, Nice, France.
Aquaronne D; Hematology Laboratory, Nice University Hospital, Nice, France.
Ferrero C; Hematology Laboratory, Nice University Hospital, Nice, France.
Fenwarth L; Hematology Laboratory, Lille University Hospital, Lille, France.
Marceau A; Hematology Laboratory, Lille University Hospital, Lille, France.
Fournier E; Hematology Laboratory, Lille University Hospital, Lille, France.
Dadone-Montaudie B; Cote d'Azur University, Nice, France.; Molecular Laboratory, Nice University Hospital, Nice, France.
Cluzeau T; Hematology department, Nice University Hospital, Nice, France.; Mediterranean Center of Molecular Medecine, INSERM, Nice, France.; Cote d'Azur University, Nice, France.
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Źródło:
Cancer medicine [Cancer Med] 2024 Mar; Vol. 13 (6), pp. e7103.
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, Myeloid, Acute*/diagnosis
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Humans ; Aged ; Nucleophosmin ; Retrospective Studies ; Prognosis ; Mutation ; Risk Assessment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Y-box binding protein 1 in small extracellular vesicles reduces mesenchymal stem cell differentiation to osteoblasts-implications for acute myeloid leukaemia.
Autorzy:
Chetty VK; Department of Pediatrics III, University Hospital Essen, Essen, Germany.
Ghanam J; Department of Pediatrics III, University Hospital Essen, Essen, Germany.
Lichá K; Department of Pediatrics III, University Hospital Essen, Essen, Germany.; Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University in Bratislava, Bratislava, Slovakia.
Brenzel A; Imaging Center Essen (IMCES), University Hospital Essen, Essen, Germany.
Reinhardt D; Department of Pediatrics III, University Hospital Essen, Essen, Germany.
Thakur BK; Department of Pediatrics III, University Hospital Essen, Essen, Germany.; European Liquid Biopsy Society, Hamburg, Germany.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Mar; Vol. 13 (3), pp. e12417.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Vesicles*/metabolism
Leukemia, Myeloid, Acute*
Mesenchymal Stem Cells*/metabolism
Child ; Humans ; Chromatography, Liquid ; Osteoblasts ; Osteogenesis ; Tandem Mass Spectrometry ; Tumor Microenvironment ; Y-Box-Binding Protein 1/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phenotypic Analysis of Hematopoietic Stem and Progenitor Cell Populations in Acute Myeloid Leukemia Based on Spectral Flow Cytometry, a 20-Color Panel, and Unsupervised Learning Algorithms.
Autorzy:
Matthes T; Hematology Service, Oncology Department, University Hospital Geneva, Rue Gabrielle Perret-Gentil, 1205 Geneva, Switzerland.; Clinical Pathology Service, Diagnostics Department, University Hospital Geneva, Rue Gabrielle Perret-Gentil, 1205 Geneva, Switzerland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 29; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, Myeloid, Acute*/drug therapy
Hematopoietic Stem Cell Transplantation*/methods
Humans ; Flow Cytometry/methods ; Unsupervised Machine Learning ; Hematopoietic Stem Cells/pathology ; Neoplasm, Residual/diagnosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Venetoclax efficacy on acute myeloid leukemia is enhanced by the combination with butyrate.
Autorzy:
Kawakatsu R; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Tadagaki K; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Yamasaki K; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Yoshida T; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 29; Vol. 14 (1), pp. 4975. Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
Butyrates*/pharmacology
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/metabolism
Sulfonamides*
Humans ; Cell Line, Tumor ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Apoptosis ; Caspases
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
[Effect of venetoclax plus chemotherapy on treatment-naive acute myeloid leukemia patients with moderate to poor cytogenetic profiles and the combination's influence on the expression of proteins of the anti-apoptoic family].
Źródło:
Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2024 Feb 23; Vol. 46 (2), pp. 161-167.
Typ publikacji:
English Abstract; Journal Article; Observational Study; Randomized Controlled Trial
MeSH Terms:
Bridged Bicyclo Compounds, Heterocyclic*
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Sulfonamides*
Adult ; Humans ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cytarabine/therapeutic use ; Cytogenetic Analysis ; Myeloid Cell Leukemia Sequence 1 Protein/therapeutic use ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 5549

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