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Tytuł:
Engineered extracellular vesicles carrying let-7a-5p for alleviating inflammation in acute lung injury.
Autorzy:
Chen SY; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Chen YL; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, 833401, Taiwan.; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 833401, Taiwan.
Li PC; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Cheng TS; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.; Department of Orthopedic Surgery, Far Eastern Memorial Hospital, New Taipei City, 220216, Taiwan.
Chu YS; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Shen YS; Department of Orthopedic Surgery, Far Eastern Memorial Hospital, New Taipei City, 220216, Taiwan.; Department of Biomedical Engineering, National Taiwan University, Taipei, 106319, Taiwan.
Chen HT; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Tsai WN; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Huang CL; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Sieber M; Bionet Therapeutics, Taipei, 114065, Taiwan.
Yeh YC; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Keelung, 204201, Taiwan.; Program in Molecular Medicine, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Liu HS; Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, 701401, Taiwan.; Center for Cancer Research, College of Medicine, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.; Teaching and Research Center, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, 812015, Taiwan.
Chiang CL; Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, 43210, USA.; Comprehensive Cancer Center, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.
Chang CH; Department of Orthopedic Surgery, Far Eastern Memorial Hospital, New Taipei City, 220216, Taiwan.; Graduate School of Biotechnology and Bioengineering, Yuan Ze University, Taoyuan, 320315, Taiwan.
Lee AS; Spot Biosystems Ltd., Palo Alto, CA, 94305, USA.
Tseng YH; Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, 112201, Taiwan.
Lee LJ; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan. .; Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, 43210, USA. .; Spot Biosystems Ltd., Palo Alto, CA, 94305, USA. .
Liao HJ; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan. .; Department of Medical Research, Far Eastern Memorial Hospital, New Taipei City, 220216, Taiwan. .
Yip HK; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, 833401, Taiwan. .; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 833401, Taiwan. .; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 833401, Taiwan. .; Department of Nursing, Asia University, Taichung, 413305, Taiwan. .; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, 404328, Taiwan. .
Huang CF; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan. .; Department of Biochemistry, School of Medicine, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan. .
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Źródło:
Journal of biomedical science [J Biomed Sci] 2024 Mar 19; Vol. 31 (1), pp. 30. Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Hyperoxia*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Extracellular Vesicles*/physiology
Acute Lung Injury*/therapy
Acute Lung Injury*/metabolism
Rats ; Animals ; Cells, Cultured ; Inflammation ; Transforming Growth Factor beta/genetics ; Transforming Growth Factor beta/metabolism ; Fibrosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bhlhe40 deficiency attenuates LPS-induced acute lung injury through preventing macrophage pyroptosis.
Autorzy:
Hu X; Department of Respiratory and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Zou M; Fourth Ward of Medical Care Center, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China.
Zheng W; Department of Respiratory and Critical Care Medicine, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China.
Zhu M; Department of Respiratory and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Hou Q; Department of Respiratory and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Gao H; Department of Respiratory and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Zhang X; Department of Respiratory and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China. .
Liu Y; Department of Respiratory and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China. .
Cheng Z; Department of Respiratory and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China. zhenshun_.; Wuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan, Hubei, China. zhenshun_.; Hubei Engineering Center for Infectious Disease Prevention, Control and Treatment, Wuhan, China. zhenshun_.
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Źródło:
Respiratory research [Respir Res] 2024 Feb 24; Vol. 25 (1), pp. 100. Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Lipopolysaccharides*/toxicity
Acute Lung Injury*/chemically induced
Acute Lung Injury*/prevention & control
Acute Lung Injury*/metabolism
Animals ; Mice ; Pyroptosis ; Macrophages/metabolism ; Caspases/adverse effects ; Inflammation ; RNA, Small Interfering ; Homeodomain Proteins/adverse effects ; Basic Helix-Loop-Helix Transcription Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Discovery of the Active Compounds of the Ethyl Acetate Extract Site of Ardisia japonica (Thunb.) Blume for the Treatment of Acute Lung Injury.
Autorzy:
Sun S; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou 450003, China.; Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-Constructed by Henan Province & Education Ministry of China, Zhengzhou 450046, China.
Liu X; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou 450003, China.; Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-Constructed by Henan Province & Education Ministry of China, Zhengzhou 450046, China.
Zhao D; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou 450003, China.; Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-Constructed by Henan Province & Education Ministry of China, Zhengzhou 450046, China.
Zheng L; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou 450003, China.; Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-Constructed by Henan Province & Education Ministry of China, Zhengzhou 450046, China.
Han X; College of Pharmacy, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Tian Y; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou 450003, China.; Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-Constructed by Henan Province & Education Ministry of China, Zhengzhou 450046, China.
Feng S; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou 450003, China.; Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-Constructed by Henan Province & Education Ministry of China, Zhengzhou 450046, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 07; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Ardisia*
Acute Lung Injury*/chemically induced
Acute Lung Injury*/drug therapy
Acetates*
Rats ; Animals ; Plant Extracts/chemistry ; Lipopolysaccharides ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Anti-Inflammatory Agents/chemistry ; Solvents/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Rosavin Alleviates LPS-Induced Acute Lung Injure by Modulating the TLR-4/NF-κB/MAPK Singnaling Pathways.
Autorzy:
Liu QH; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi 832002, China.
Zhang K; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi 832002, China.
Feng SS; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi 832002, China.
Zhang LJ; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi 832002, China.
Li SY; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi 832002, China.
Wang HY; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi 832002, China.
Wang JH; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi 832002, China.; State-Province Key Laboratory of Biomedicine-Pharmaceutics of China, Department of Medicinal Chemistry and Natural Medicine Chemistry, Harbin Medical University, Harbin 150081, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 03; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 03.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury*/chemically induced
Acute Lung Injury*/drug therapy
Disaccharides*/therapeutic use
Animals ; Mice ; Anti-Inflammatory Agents/adverse effects ; Lipopolysaccharides/toxicity ; Lung/pathology ; NF-kappa B/metabolism ; Toll-Like Receptor 4/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Blockage of mechanosensitive Piezo1 channel alleviates the severity of experimental malaria-associated acute lung injury.
Autorzy:
Zhang M; Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Wang QR; Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Hou X; Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Wang Q; Guangzhou Chest Hospital, Guangzhou, 510095, People's Republic of China.
Yang X; Department of Laboratory Medicine, Central Hospital of Panyu District, Guangzhou, 511400, People's Republic of China.
Zhou T; Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Liu X; School of Basic Medical Science, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Wu L; Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Wang J; Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Jin X; Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Liu Z; Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, QC, Canada. .
Huang B; Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China. .; School of Basic Medical Science, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China. .
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Źródło:
Parasites & vectors [Parasit Vectors] 2024 Feb 01; Vol. 17 (1), pp. 46. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury*/drug therapy
Acute Lung Injury*/parasitology
Ion Channels*/antagonists & inhibitors
Malaria, Cerebral*/complications
Malaria, Cerebral*/drug therapy
Spider Venoms*/therapeutic use
Intercellular Signaling Peptides and Proteins*/therapeutic use
Animals ; Mice ; Cytokines/genetics ; Cytokines/metabolism ; Interleukin-10/metabolism ; Interleukin-4 ; Lipopolysaccharides ; Lung/parasitology ; Mice, Inbred C57BL ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Asiatic acid cyclodextrin inclusion micro-cocrystal for insoluble drug delivery and acute lung injury therapy enhancement.
Autorzy:
Shen H; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.; State Key Laboratory of Drug Research, Chinese Academy of Sciences, Shanghai, 201203, China.
Pan L; School of Pharmacy, Zunyi Medical University, Zunyi, 563003, China.
Ning K; School of Pharmacy, Zunyi Medical University, Zunyi, 563003, China.
Fang Y; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.
Muhitdinov B; Institute of Bioorganic Chemistry, Uzbekistan Academy of Sciences, 83 M. Ulughbek Street, Tashkent, 100125, Uzbekistan.
Liu E; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China. .
Huang Y; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China. .; State Key Laboratory of Drug Research, Chinese Academy of Sciences, Shanghai, 201203, China. .; School of Pharmacy, Zunyi Medical University, Zunyi, 563003, China. .; NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients, Shanghai, 201203, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Mar 17; Vol. 22 (1), pp. 119. Date of Electronic Publication: 2024 Mar 17.
Typ publikacji:
Journal Article
MeSH Terms:
Cyclodextrins*/chemistry
Acute Lung Injury*/drug therapy
Pentacyclic Triterpenes*
Humans ; Tissue Distribution ; Drug Delivery Systems ; Solubility
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Saponins from Allium macrostemon Bulbs Attenuate Endothelial Inflammation and Acute Lung Injury via the NF-κB/VCAM-1 Pathway.
Autorzy:
Liu L; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Qiu L; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Xue J; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Zhong C; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.; Department of Cardiovascular Sciences and Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Qin M; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Zhang Y; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Xu C; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Xie Y; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Yu J; Department of Cardiovascular Sciences and Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Mar 11; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 11.
Typ publikacji:
Journal Article
MeSH Terms:
Saponins*/pharmacology
Acute Lung Injury*/drug therapy
Drugs, Chinese Herbal*
Chive*
Humans ; Animals ; Mice ; NF-kappa B/metabolism ; Vascular Cell Adhesion Molecule-1/genetics ; Vascular Cell Adhesion Molecule-1/metabolism ; Lipopolysaccharides/toxicity ; Inflammation/drug therapy ; Inflammation/prevention & control ; Human Umbilical Vein Endothelial Cells ; Tumor Necrosis Factor-alpha/pharmacology ; Inflammation Mediators/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MUC5AC concentrations in lung lavage fluids are associated with acute lung injury after cardiac surgery.
Autorzy:
van Paassen J; Department of Intensive Care, Leiden University Medical Center, Albinusdreef 2, Leiden, B4-57, 2333 ZA, the Netherlands. j.van_.
Hiemstra PS; Department of Pulmonology, Leiden University Medical Centre, Leiden, the Netherlands.
van der Linden AC; Department of Pulmonology, Leiden University Medical Centre, Leiden, the Netherlands.
de Jonge E; Department of Intensive Care, Leiden University Medical Center, Albinusdreef 2, Leiden, B4-57, 2333 ZA, the Netherlands.
Zwaginga JJ; Center for Clinical Transfusion Research, Sanquin Research, Leiden, the Netherlands.; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands.
Klautz RJM; Department of Thoracic Surgery, Leiden University Medical Center, Leiden, the Netherlands.
Arbous MS; Department of Intensive Care, Leiden University Medical Center, Albinusdreef 2, Leiden, B4-57, 2333 ZA, the Netherlands.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
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Źródło:
Respiratory research [Respir Res] 2024 Mar 07; Vol. 25 (1), pp. 117. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Letter
MeSH Terms:
Acute Lung Injury*/diagnosis
Acute Lung Injury*/etiology
Cardiac Surgical Procedures*/adverse effects
Adult ; Humans ; Bronchoalveolar Lavage Fluid ; Prospective Studies ; Biomarkers/analysis ; Mucin 5AC/metabolism
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Autorzy:
Huang W; Department of Respiratory and Critical Care Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Wang L; Department of Respiratory and Critical Care Medicine, Guangxi Hospital Division of The First Affiliated Hospital, Sun Yat-sen University, Guangxi, China.
Huang Z; Dongguan Hospital of Integrated Chinese and Western Medicine, Dongguan, China.
Sun Z; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Zheng B; Department of Critical Care Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China. .
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Źródło:
Respiratory research [Respir Res] 2024 Mar 02; Vol. 25 (1), pp. 110. Date of Electronic Publication: 2024 Mar 02.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury*/metabolism
Macrophages*/metabolism
Peroxiredoxin III*/metabolism
Humans ; Inflammation/metabolism ; Lipopolysaccharides ; Mitochondrial Diseases/complications ; Mitochondrial Diseases/metabolism ; Sepsis/metabolism ; Animals ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Fortunellin ameliorates LPS-induced acute lung injury, inflammation, and collagen deposition by restraining the TLR4/NF-κB/NLRP3 pathway.
Autorzy:
Liu D; Department of Critical Care Medicine, the Affiliated Hospital of Putian University, Putian, China.
Guo R; Department of Critical Care Medicine, the Affiliated Hospital of Putian University, Putian, China.
Shi B; Department of Critical Care Medicine, the Affiliated Hospital of Putian University, Putian, China.
Chen M; Department of Critical Care Medicine, the Affiliated Hospital of Putian University, Putian, China.
Weng S; School of Ophthalmology & Optometry, Wenzhou Medical University, Wenzhou, China.
Weng J; Department of Critical Care Medicine, the Affiliated Hospital of Putian University, Putian, China.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2024 Mar; Vol. 12 (3), pp. e1164.
Typ publikacji:
Journal Article
MeSH Terms:
NF-kappa B*/metabolism
Acute Lung Injury*/chemically induced
Acute Lung Injury*/metabolism
Flavonoids*
Glycosides*
Animals ; Mice ; Lipopolysaccharides/toxicity ; Toll-Like Receptor 4/metabolism ; Signal Transduction ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Inflammation ; Collagen
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pyroptosis and polarization of macrophages in septic acute lung injury induced by lipopolysaccharide in mice.
Autorzy:
Zhou S; Department of Emergency, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Yang X; Department of General Medicine, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Mo K; Department of Respiratory Medicine, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Ning Z; Department of General Medicine, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2024 Mar; Vol. 12 (3), pp. e1197.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Acute Lung Injury*
Sepsis*
Animals ; Mice ; Lipopolysaccharides/toxicity ; Interleukin-18 ; NLR Family, Pyrin Domain-Containing 3 Protein ; Pyroptosis ; Caspase 1 ; Macrophages ; Caspases
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Therapeutic Effects of a Novel Aptamer on Coronaviral Infection-Induced Lung Injury and Systemic Inflammatory Responses.
Autorzy:
Wang Y; Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, ON M5G 1L7, Canada.
Lindstam M; Aptahem AB, 211 22 Malmo, Sweden.
Hwang D; Department of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
Jedlina L; Aptahem AB, 211 22 Malmo, Sweden.
Liu M; Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, ON M5G 1L7, Canada.; Department of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.; Departments of Surgery, Medicine, and Physiology, Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
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Źródło:
Cells [Cells] 2024 Feb 28; Vol. 13 (5). Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Murine hepatitis virus*
Acute Lung Injury*
Female ; Animals ; Mice ; Lung ; Hemorrhage ; Bilirubin ; Anti-Inflammatory Agents
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
FGF18 alleviates sepsis-induced acute lung injury by inhibiting the NF-κB pathway.
Autorzy:
Hu Z; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Dai J; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Xu T; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Chen H; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Shen G; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Zhou J; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Ma H; School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Wang Y; School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China. .
Jin L; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China. jin_.
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Źródło:
Respiratory research [Respir Res] 2024 Feb 28; Vol. 25 (1), pp. 108. Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury*/metabolism
Sepsis*/metabolism
Fibroblast Growth Factors*
Mice ; Humans ; Animals ; NF-kappa B/metabolism ; Lipopolysaccharides/toxicity ; Mice, Inbred C57BL ; Lung/metabolism ; Human Umbilical Vein Endothelial Cells/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis and Anti-Inflammatory Activity of Ferulic Acid-Sesquiterpene Lactone Hybrids.
Autorzy:
Duan X; School of Chemistry & Chemical Engineering, Henan University of Science and Technology, Luoyang 471003, China.
Liu N; School of Nursing, Henan University of Science and Technology, Luoyang 471003, China.
Lv K; The State Key Laboratory of Medicinal Chemical Biology & College of Chemistry, Nankai University, Tianjin 300071, China.
Wang J; School of Chemistry & Chemical Engineering, Henan University of Science and Technology, Luoyang 471003, China.
Li M; College of Pharmacy, Nankai University, Tianjin 300071, China.
Zhang Y; Accendatech Company, Ltd., Tianjin 300384, China.
Huo X; Accendatech Company, Ltd., Tianjin 300384, China.
Bao S; Accendatech Company, Ltd., Tianjin 300384, China.
Shen Z; Accendatech Company, Ltd., Tianjin 300384, China.
Zhang X; Accendatech Company, Ltd., Tianjin 300384, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 21; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury*/drug therapy
Sesquiterpenes*/pharmacology
Coumaric Acids*
Humans ; Animals ; Mice ; Lipopolysaccharides/adverse effects ; Anti-Inflammatory Agents/pharmacology ; Lung/metabolism ; Cytokines/metabolism ; Lactones/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ferritin-mediated neutrophil extracellular traps formation and cytokine storm via macrophage scavenger receptor in sepsis-associated lung injury.
Autorzy:
Zhang H; Department of Anesthesiology, Zhongshan Hospital, Fudan University, 180# Feng-Lin Road, Shanghai, 200032, China. .; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai, China. .; Department of Anesthesiology, Shanghai Medical College, Fudan University, Shanghai, China. .
Wu D; Department of Anesthesiology, Zhongshan Hospital, Fudan University, 180# Feng-Lin Road, Shanghai, 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai, China.; Department of Anesthesiology, Shanghai Medical College, Fudan University, Shanghai, China.
Wang Y; Department of Anesthesiology, Zhongshan Hospital, Fudan University, 180# Feng-Lin Road, Shanghai, 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai, China.; Department of Anesthesiology, Shanghai Medical College, Fudan University, Shanghai, China.
Shi Y; Department of Anesthesiology, Zhongshan Hospital, Fudan University, 180# Feng-Lin Road, Shanghai, 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai, China.; Department of Anesthesiology, Shanghai Medical College, Fudan University, Shanghai, China.
Shao Y; Department of Anesthesiology, Zhongshan Hospital, Fudan University, 180# Feng-Lin Road, Shanghai, 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai, China.; Department of Anesthesiology, Shanghai Medical College, Fudan University, Shanghai, China.
Zeng F; Department of Anesthesiology, Zhongshan Hospital, Fudan University, 180# Feng-Lin Road, Shanghai, 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai, China.; Department of Anesthesiology, Shanghai Medical College, Fudan University, Shanghai, China.
Spencer CB; Department of Cardiac surgery, The Ohio State University, Columbus, USA.
Ortoga L; Department of Biomedical Engineering, The Ohio State University, Columbus, USA.
Wu D; Department of Anesthesiology, Shanghai Songjiang District Central Hospital, Shanghai, China. .
Miao C; Department of Anesthesiology, Zhongshan Hospital, Fudan University, 180# Feng-Lin Road, Shanghai, 200032, China. miaochanghong_.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai, China. miaochanghong_.; Department of Anesthesiology, Shanghai Medical College, Fudan University, Shanghai, China. miaochanghong_.
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Feb 02; Vol. 22 (1), pp. 97. Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Extracellular Traps*/metabolism
Sepsis*/complications
Sepsis*/metabolism
Acute Lung Injury*/metabolism
Humans ; Mice ; Animals ; Cytokine Release Syndrome ; Reactive Oxygen Species/metabolism ; Neutrophils/metabolism ; Inflammation/metabolism ; Receptors, Scavenger/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Manufacturing, quality control, and GLP-grade preclinical study of nebulized allogenic adipose mesenchymal stromal cells-derived extracellular vesicles.
Autorzy:
Wang J; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Chen ZJ; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Zhang ZY; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Shen MP; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Zhao B; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Zhang W; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Zhang Y; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Lei JG; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Ren CJ; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Chang J; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Xu CL; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Li M; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Pi YY; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Lu TL; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China.
Dai CX; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China. .; Daxing Research Institute, University of Science and Technology Beijing, 100083, Beijing, China. .
Li SK; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China. .
Li P; Cellular Biomedicine Group (Shanghai), Co. Ltd., 85 Faladi Road, Building 3, Zhangjiang, Pudong New Area, 201210, Shanghai, China. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2024 Apr 02; Vol. 15 (1), pp. 95. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury*/therapy
Respiratory Distress Syndrome*/therapy
Extracellular Vesicles*/physiology
Mesenchymal Stem Cells*/physiology
Humans ; Rats ; Animals ; Chromatography, Liquid ; Proteomics ; Lipopolysaccharides/pharmacology ; Tandem Mass Spectrometry ; Obesity ; Quality Control
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Respiratory entrainment related reverse triggering in mechanically ventilated children.
Autorzy:
Blokpoel RGT; Department of Paediatrics, Division of Paediatric Intensive Care, Beatrix Children's Hospital, University Medical Center Groningen, P.O. Box 30.001 9700 RB, Groningen, CA 62, the Netherlands. .
Brandsema RBR; Department of Paediatrics, Division of Paediatric Intensive Care, Beatrix Children's Hospital, University Medical Center Groningen, P.O. Box 30.001 9700 RB, Groningen, CA 62, the Netherlands.
Koopman AA; Department of Paediatrics, Division of Paediatric Intensive Care, Beatrix Children's Hospital, University Medical Center Groningen, P.O. Box 30.001 9700 RB, Groningen, CA 62, the Netherlands.
van Dijk J; Department of Paediatrics, Division of Paediatric Intensive Care, Beatrix Children's Hospital, University Medical Center Groningen, P.O. Box 30.001 9700 RB, Groningen, CA 62, the Netherlands.
Kneyber MCJ; Department of Paediatrics, Division of Paediatric Intensive Care, Beatrix Children's Hospital, University Medical Center Groningen, P.O. Box 30.001 9700 RB, Groningen, CA 62, the Netherlands.; Critical Care, Anesthesia, Peri-operative medicine & Emergency Medicine (CAPE), University of Groningen, Groningen, the Netherlands.
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Źródło:
Respiratory research [Respir Res] 2024 Mar 25; Vol. 25 (1), pp. 142. Date of Electronic Publication: 2024 Mar 25.
Typ publikacji:
Journal Article
MeSH Terms:
Respiration, Artificial*/adverse effects
Acute Lung Injury*
Child ; Humans ; Child, Preschool ; Prospective Studies ; Respiration ; Ventilators, Mechanical
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Endothelial cell-derived extracellular vesicles expressing surface VCAM1 promote sepsis-related acute lung injury by targeting and reprogramming monocytes.
Autorzy:
Wang L; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Tang Y; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Tang J; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Liu X; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Zi S; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Li S; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Chen H; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Liu A; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Huang W; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Xie J; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Liu L; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Chao J; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.; Department of Physiology, School of Medicine, Southeast University, Nanjing, China.
Qiu H; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Mar; Vol. 13 (3), pp. e12423.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury*/metabolism
Extracellular Vesicles*/metabolism
Monocytes*/metabolism
Sepsis*/complications
Sepsis*/metabolism
Vascular Cell Adhesion Molecule-1*/metabolism
Humans ; Endothelial Cells/metabolism ; Respiratory Distress Syndrome/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Circ-phkb promotes cell apoptosis and inflammation in LPS-induced alveolar macrophages via the TLR4/MyD88/NF-kB/CCL2 axis.
Autorzy:
Wei X; Surgical Intensive Care Unit, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600, Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China.
Yi X; Surgical Intensive Care Unit, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600, Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China.
Liu J; Surgical Intensive Care Unit, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600, Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China.
Sui X; Surgical Intensive Care Unit, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600, Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China.
Li L; Surgical Intensive Care Unit, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600, Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China.
Li M; VIP Healthcare Center, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600, Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China. .
Lv H; Surgical Intensive Care Unit, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600, Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China. .
Yi H; Surgical Intensive Care Unit, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600, Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China. .
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Źródło:
Respiratory research [Respir Res] 2024 Jan 29; Vol. 25 (1), pp. 62. Date of Electronic Publication: 2024 Jan 29.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury*/chemically induced
Acute Lung Injury*/genetics
Acute Lung Injury*/metabolism
MicroRNAs*/genetics
Rats ; Animals ; NF-kappa B/metabolism ; Macrophages, Alveolar/metabolism ; Lipopolysaccharides/toxicity ; Myeloid Differentiation Factor 88/genetics ; Myeloid Differentiation Factor 88/metabolism ; Toll-Like Receptor 4/genetics ; RNA, Circular/genetics ; Apoptosis ; Inflammation/metabolism ; RNA, Messenger/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Glycogen Synthase Kinase-3 Inhibition by CHIR99021 Promotes Alveolar Epithelial Cell Proliferation and Lung Regeneration in the Lipopolysaccharide-Induced Acute Lung Injury Mouse Model.
Autorzy:
Fernandes R; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4806-909 Braga, Portugal.
Barbosa-Matos C; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4806-909 Braga, Portugal.
Borges-Pereira C; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4806-909 Braga, Portugal.
Carvalho ALRT; Department of Internal Medicine, São João Universitary Hospital Center, 4200-319 Porto, Portugal.; Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
Costa S; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4806-909 Braga, Portugal.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 20; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 20.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*
Acute Lung Injury*/chemically induced
Acute Lung Injury*/pathology
Pyridines*
Pyrimidines*
Animals ; Mice ; Lipopolysaccharides/pharmacology ; Glycogen Synthase Kinase 3 ; Lung/pathology ; Cell Proliferation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 19588

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