Tracking genomic cancer evolution for precision medicine: the lung TRACERx study.
Autorzy:
Jamal-Hanjani M; Translational Cancer Therapeutics Laboratory, University College London Cancer Institute, London, United Kingdom; Department of Medical Oncology, University College London Hospitals, London, United Kingdom. Hackshaw A; Cancer Research UK & UCL Cancer Trials Centre, London, United Kingdom. Ngai Y; Cancer Research UK & UCL Cancer Trials Centre, London, United Kingdom. Shaw J; Cancer Studies and Molecular Medicine, University of Leicester, Leicester, United Kingdom. Dive C; Cancer Research UK Manchester Institute, Manchester, United Kingdom. Quezada S; Immune Regulation and Tumour Immunotherapy Laboratory, University College London Cancer Institute, London, United Kingdom. Middleton G; Department of Medical Oncology, Birmingham Heartlands Hospital, Birmingham, United Kingdom. de Bruin E; Translational Cancer Therapeutics Laboratory, University College London Cancer Institute, London, United Kingdom. Le Quesne J; Cancer Studies and Molecular Medicine, University of Leicester, Leicester, United Kingdom. Shafi S; Translational Cancer Therapeutics Laboratory, University College London Cancer Institute, London, United Kingdom. Falzon M; Department of Pathology, University College London Hospitals, London, United Kingdom. Horswell S; Department of Bioinformatics and BioStatistics, Cancer Research UK, London Research Institute, London, United Kingdom. Blackhall F; Institute of Cancer Studies, University of Manchester and The Christie Hospital, Manchester, United Kingdom. Khan I; Cancer Research UK & UCL Cancer Trials Centre, London, United Kingdom. Janes S; Department of Respiratory Medicine, University College London Hospitals, London, United Kingdom. Nicolson M; Department of Medical Oncology, Aberdeen University Medical School & Aberdeen Royal Infirmary, Aberdeen, Scotland, United Kingdom. Lawrence D; Department of Cardiothoracic Surgery, Heart Hospital, London, United Kingdom. Forster M; Department of Medical Oncology, University College London Hospitals, London, United Kingdom. Fennell D; Cancer Studies and Molecular Medicine, University of Leicester, Leicester, United Kingdom; Department of Medical Oncology, University of Leicester & Leicester University Hospitals, Leicester, United Kingdom. Lee SM; Department of Medical Oncology, University College London Hospitals, London, United Kingdom. Lester J; Department of Clinical Oncology, Velindre Hospital, Cardiff, Wales, United Kingdom. Kerr K; Department of Pathology, Aberdeen University Medical School & Aberdeen Royal Infirmary, Aberdeen, Scotland, United Kingdom. Muller S; Department of Pathology, University of Leicester & Leicester University Hospitals, Leicester, United Kingdom. Iles N; Cancer Research UK & UCL Cancer Trials Centre, London, United Kingdom. Smith S; Cancer Research UK & UCL Cancer Trials Centre, London, United Kingdom. Murugaesu N; Translational Cancer Therapeutics Laboratory, University College London Cancer Institute, London, United Kingdom; Department of Medical Oncology, University College London Hospitals, London, United Kingdom. Mitter R; Department of Bioinformatics and BioStatistics, Cancer Research UK, London Research Institute, London, United Kingdom. Salm M; Department of Bioinformatics and BioStatistics, Cancer Research UK, London Research Institute, London, United Kingdom. Stuart A; Department of Bioinformatics and BioStatistics, Cancer Research UK, London Research Institute, London, United Kingdom. Matthews N; The Advanced Sequencing Facility, London Research Institute, London, United Kingdom. Adams H; Department of Radiology, University Hospital Llandough, Cardiff, Wales, United Kingdom. Ahmad T; Department of Medical Oncology, University College London Hospitals, London, United Kingdom. Attanoos R; Department of Pathology, University Hospital Llandough, Cardiff, Wales, United Kingdom. Bennett J; Department of Respiratory Medicine, University of Leicester & Leicester University Hospitals, Leicester, United Kingdom. Birkbak NJ; Department of Systems Biology, Technical University of Denmark, Kongens Lyngby, Denmark. Booton R; Department of Respiratory Medicine, University Hospital of South Manchester, Manchester, United Kingdom. Brady G; Cancer Research UK Manchester Institute, Manchester, United Kingdom. Buchan K; Department of Cardiothoracic Surgery, Aberdeen University Medical School & Aberdeen Royal Infirmary, Aberdeen, United Kingdom. Capitano A; Department of Pathology, University College London Hospitals, London, United Kingdom. Chetty M; Department of Respiratory Medicine, Aberdeen University Medical School & Aberdeen Royal Infirmary, Aberdeen, United Kingdom. Cobbold M; Department of Clinical Immunology, University of Birmingham, Birmingham, B15 2TT. Crosbie P; North West Lung Centre, University Hospital of South Manchester, Manchester, United Kingdom. Davies H; Department of Respiratory Medicine, University Hospital Llandough, Cardiff, Wales, United Kingdom. Denison A; Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, United kingdom. Djearman M; Department of Radiology, Birmingham Heartlands Hospital, Birmingham, United Kingdom. Goldman J; Department of IT, London Research Institute, London, United Kingdom. Haswell T; Independent Cancer Patient's Voice, London, united Kingdom. Joseph L; Department of Pathology, University Hospitals of South Manchester, Manchester. Kornaszewska M; Department of Cardiothoracic Surgery, University Hospital Llandough, Cardiff, Wales, United Kingdom. Krebs M; Cancer Research UK Manchester Institute, Manchester, United Kingdom. Langman G; Department of Cellular Pathology, Birmingham Heartlands Hospital, Birmingham, United Kingdom. MacKenzie M; Independent Cancer Patient's Voice, London, united Kingdom. Millar J; Department of Respiratory Medicine, Aberdeen University Medical School & Aberdeen Royal Infirmary, Aberdeen, United Kingdom. Morgan B; Cancer Studies and Molecular Medicine, University of Leicester, Leicester, United Kingdom. Naidu B; Department of Thoracic Surgery, Birmingham Heartlands Hospital, Birmingham, United Kingdom. Nonaka D; The Christie Hospital, Manchester, United Kingdom; Department of Pathology, University Hospitals of South Manchester, Manchester. Peggs K; Immune Regulation and Tumour Immunotherapy Laboratory, University College London Cancer Institute, London, United Kingdom. Pritchard C; Department of Biochemistry, University of Leicester, Leicester, United Kingdom. Remmen H; Department of Cardiothoracic Surgery, Aberdeen University Medical School & Aberdeen Royal Infirmary, Aberdeen, United Kingdom. Rowan A; Translational Cancer Therapeutics Laboratory, London Research Institute, London, United Kingdom. Shah R; Department of Cardiothoracic Surgery, University Hospitals of South Manchester, Manchester, United Kingdom. Smith E; Department of Radiology, University Hospitals of South Manchester, Manchester, United Kingdom. Summers Y; The Christie Hospital, Manchester, United Kingdom; Department of Medical Oncology, University Hospital of South Manchester, Manchester, United Kingdom. Taylor M; Department of Radiology, University College London Hospitals, London, United Kingdom. Veeriah S; Translational Cancer Therapeutics Laboratory, University College London Cancer Institute, London, United Kingdom. Waller D; Department of Cardiothoracic Surgery, University of Leicester & Leicester University Hospitals, Leicester, United Kingdom. Wilcox B; School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom. Wilcox M; Independent Cancer Patient's Voice, London, united Kingdom. Woolhouse I; Department of Respiratory Medicine, Birmingham University Hospital, Birmingham, United Kingdom. McGranahan N; Translational Cancer Therapeutics Laboratory, London Research Institute, London, United Kingdom. Swanton C; Translational Cancer Therapeutics Laboratory, University College London Cancer Institute, London, United Kingdom; Department of Medical Oncology, University College London Hospitals, London, United Kingdom; Translational Cancer Therapeutics Laboratory, London Research Institute, London, United Kingdom.
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Źródło:
PLoS biology [PLoS Biol] 2014 Jul 08; Vol. 12 (7), pp. e1001906. Date of Electronic Publication: 2014 Jul 08 (Print Publication: 2014).
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