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Ви шукаєте ""Adaptor Proteins, Signal Transducing"" за критеріями: Temat


Tytuł:
Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Autorzy:
Singh K; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
Lau CK; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
Manigrasso G; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
Gama JB; Instituto de Investigação e Inovação em Saúde (i3S)/Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, 4200-135 Porto, Portugal.
Gassmann R; Instituto de Investigação e Inovação em Saúde (i3S)/Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, 4200-135 Porto, Portugal.
Carter AP; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar 29; Vol. 383 (6690), pp. eadk8544. Date of Electronic Publication: 2024 Mar 29.
Typ publikacji:
Journal Article
MeSH Terms:
Dynactin Complex*/chemistry
Dynactin Complex*/genetics
Dynactin Complex*/metabolism
Dyneins*/chemistry
Dyneins*/genetics
Dyneins*/metabolism
Microtubule-Associated Proteins*/chemistry
Microtubule-Associated Proteins*/metabolism
1-Alkyl-2-acetylglycerophosphocholine Esterase*
Nerve Tissue Proteins*/chemistry
Nerve Tissue Proteins*/metabolism
Adaptor Proteins, Signal Transducing*/chemistry
Adaptor Proteins, Signal Transducing*/metabolism
Cryoelectron Microscopy ; Microtubules/metabolism ; Protein Binding ; Humans ; HeLa Cells ; WD40 Repeats ; Protein Interaction Mapping
Czasopismo naukowe
Tytuł:
STAP-2 facilitates insulin signaling through binding to CAP/c-Cbl and regulates adipocyte differentiation.
Autorzy:
Sekine Y; Department of Cell Biology, Kyoto Pharmaceutical University, Kyoto, 607-8412, Japan. .
Kikkawa K; Department of Cell Biology, Kyoto Pharmaceutical University, Kyoto, 607-8412, Japan.
Honda S; Department of Cell Biology, Kyoto Pharmaceutical University, Kyoto, 607-8412, Japan.
Sasaki Y; Department of Immunology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, 060-0812, Japan.
Kawahara S; Department of Immunology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, 060-0812, Japan.
Mizushima A; Department of Immunology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, 060-0812, Japan.
Togi S; Division of Genomic Medicine, Department of Advanced Medicine, Medical Research Institute, Kanazawa Medical University, Kahoku, Ishikawa, 920-0293, Japan.
Fujimuro M; Department of Cell Biology, Kyoto Pharmaceutical University, Kyoto, 607-8412, Japan.
Oritani K; Department of Hematology, International University of Health and Welfare, Narita, Chiba, 286-8686, Japan.
Matsuda T; Department of Immunology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, 060-0812, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 09; Vol. 14 (1), pp. 5799. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Adaptor Proteins, Signal Transducing*/genetics
Adaptor Proteins, Signal Transducing*/metabolism
Insulin*/metabolism
Cell Differentiation*/genetics
Animals ; Humans ; Mice ; Adipocytes/metabolism ; Fibroblasts/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
TRIP6 a potential diagnostic marker for colorectal cancer with glycolysis and immune infiltration association.
Autorzy:
Liu XS; Department of Nuclear Medicine, Hubei Provincial Clinical Research Center for precision Diagnosis and Treatment of liver cancer, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China.; Hubei Provincial Clinical Research Center for Umbilical Cord Blood Hematopoietic Stem Cells, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, China.; Hubei Key Laboratory of Embryonic Stem Cell Research, Shiyan, 442000, Hubei, China.
Chen YX; Department of Nuclear Medicine, Hubei Provincial Clinical Research Center for precision Diagnosis and Treatment of liver cancer, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China.
Wan HB; Department of Nuclear Medicine, Hubei Provincial Clinical Research Center for precision Diagnosis and Treatment of liver cancer, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China.
Wang YL; Department of Nuclear Medicine, Hubei Provincial Clinical Research Center for precision Diagnosis and Treatment of liver cancer, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China.
Wang YY; Department of Nuclear Medicine, Hubei Provincial Clinical Research Center for precision Diagnosis and Treatment of liver cancer, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China.
Gao Y; Department of Nuclear Medicine, Hubei Provincial Clinical Research Center for precision Diagnosis and Treatment of liver cancer, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China.
Wu LB; Department of Nuclear Medicine, Hubei Provincial Clinical Research Center for precision Diagnosis and Treatment of liver cancer, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China. .
Pei ZJ; Department of Nuclear Medicine, Hubei Provincial Clinical Research Center for precision Diagnosis and Treatment of liver cancer, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China. .; Hubei Provincial Clinical Research Center for Umbilical Cord Blood Hematopoietic Stem Cells, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, China. .; Hubei Key Laboratory of Embryonic Stem Cell Research, Shiyan, 442000, Hubei, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 19; Vol. 14 (1), pp. 4042. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article
MeSH Terms:
Adaptor Proteins, Signal Transducing*/genetics
Adaptor Proteins, Signal Transducing*/metabolism
Colorectal Neoplasms*/diagnosis
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
LIM Domain Proteins*/genetics
LIM Domain Proteins*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
Humans ; Glycolysis ; Proteasome Endopeptidase Complex/metabolism
Czasopismo naukowe
Tytuł:
Role of CARD9 in Cell- and Organ-Specific Immune Responses in Various Infections.
Autorzy:
Lee JS; Laboratory of Leukocyte Signaling Research, Department of Pharmacology, Inha University School of Medicine, Incheon 22212, Republic of Korea.; BK21, Program in Biomedical Science & Engineering, Inha University, Incheon 22212, Republic of Korea.
Kim C; Laboratory of Leukocyte Signaling Research, Department of Pharmacology, Inha University School of Medicine, Incheon 22212, Republic of Korea.; BK21, Program in Biomedical Science & Engineering, Inha University, Incheon 22212, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 23; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cytokines*/metabolism
Adaptor Proteins, Signal Transducing*/metabolism
Humans ; Animals ; Mice ; Immunity ; Signal Transduction ; Macrophages/metabolism ; CARD Signaling Adaptor Proteins/metabolism
Czasopismo naukowe
Tytuł:
PARD3 drives tumorigenesis through activating Sonic Hedgehog signalling in tumour-initiating cells in liver cancer.
Autorzy:
Wu J; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Tan HY; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Centre for Chinese Medicine Drug Development, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Chan YT; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Lu Y; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Feng Z; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Yuan H; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Zhang C; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Feng Y; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Wang N; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Feb 06; Vol. 43 (1), pp. 42. Date of Electronic Publication: 2024 Feb 06.
Typ publikacji:
Journal Article
MeSH Terms:
Adaptor Proteins, Signal Transducing*/metabolism
Carcinoma, Hepatocellular*/pathology
Cell Cycle Proteins*/metabolism
Liver Neoplasms*/pathology
Humans ; Carcinogenesis/metabolism ; Cell Line, Tumor ; Cell Transformation, Neoplastic/metabolism ; Choline/metabolism ; Hedgehog Proteins/genetics ; Hedgehog Proteins/metabolism ; Neoplastic Stem Cells/metabolism ; RNA, Guide, CRISPR-Cas Systems
Czasopismo naukowe
Tytuł:
CD2AP is a potential prognostic biomarker of renal clear cell carcinoma.
Autorzy:
Chen C; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.
Xu J; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.
Zhang JX; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.
Chen LY; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.
Wei YA; Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zhang WM; Department of Pathology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Shao PF; Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xu HG; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.
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Źródło:
Cancer medicine [Cancer Med] 2024 Feb; Vol. 13 (4), pp. e7055.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Renal Cell*/genetics
Carcinoma*
Kidney Neoplasms*/genetics
Cytoskeletal Proteins*
Adaptor Proteins, Signal Transducing*
Humans ; DNA Copy Number Variations ; Prognosis ; Biomarkers
Czasopismo naukowe
Tytuł:
The Interaction between CLSPN Gene Polymorphisms and Alcohol Consumption Contributes to Oral Cancer Progression.
Autorzy:
Hsieh MJ; Oral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.; Doctoral Program in Tissue Engineering and Regenerative Medicine, College of Medicine, National Chung Hsing University, Taichung 402, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 404, Taiwan.
Lo YS; Oral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Ho HY; Oral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Lin CC; Oral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Chuang YC; Oral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Chen MK; Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, Changhua 500, Taiwan.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung 402, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 16; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 16.
Typ publikacji:
Journal Article
MeSH Terms:
Adaptor Proteins, Signal Transducing*/genetics
Mouth Neoplasms*/genetics
Squamous Cell Carcinoma of Head and Neck*/genetics
Humans ; Alcohol Drinking/genetics ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł:
Advanced glycation end products impair bone marrow mesenchymal stem cells osteogenesis in periodontitis with diabetes via FTO-mediated N -methyladenosine modification of sclerostin.
Autorzy:
Zhou J; College of Stomatology, Chongqing Medical University, Chongqing, People's Republic of China.; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Zhu Y; College of Stomatology, Chongqing Medical University, Chongqing, People's Republic of China.; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Ai D; College of Stomatology, Chongqing Medical University, Chongqing, People's Republic of China.; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Zhou M; College of Stomatology, Chongqing Medical University, Chongqing, People's Republic of China.; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Li H; College of Stomatology, Chongqing Medical University, Chongqing, People's Republic of China.; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Li G; College of Stomatology, Chongqing Medical University, Chongqing, People's Republic of China.; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Zheng L; College of Stomatology, Chongqing Medical University, Chongqing, People's Republic of China.; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Song J; College of Stomatology, Chongqing Medical University, Chongqing, People's Republic of China. .; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China. .; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Nov 04; Vol. 21 (1), pp. 781. Date of Electronic Publication: 2023 Nov 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alpha-Ketoglutarate-Dependent Dioxygenase FTO*/genetics
Diabetes Mellitus*
Mesenchymal Stem Cells*
Periodontitis*/genetics
Adaptor Proteins, Signal Transducing*/genetics
Humans ; Bone Marrow Cells/metabolism ; Cell Differentiation ; Cells, Cultured ; Glycation End Products, Advanced/pharmacology ; Osteogenesis ; RNA/metabolism
Czasopismo naukowe
Tytuł:
Unmasking the tumourigenic role of SIN1/MAPKAP1 in the mTOR complex 2.
Autorzy:
Ezine E; INSERM, U976, Team 1, Human Immunology Pathophysiology & Immunotherapy (HIPI), Paris, France.; Département de Dermatologie, Hôpital Saint Louis, AP-HP, Paris, France.
Lebbe C; INSERM, U976, Team 1, Human Immunology Pathophysiology & Immunotherapy (HIPI), Paris, France.; Département de Dermatologie, Hôpital Saint Louis, AP-HP, Paris, France.; Université Paris Cité, Institut de Recherche Saint Louis (IRSL), Paris, France.
Dumaz N; INSERM, U976, Team 1, Human Immunology Pathophysiology & Immunotherapy (HIPI), Paris, France.; Université Paris Cité, Institut de Recherche Saint Louis (IRSL), Paris, France.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Oct; Vol. 13 (10), pp. e1464.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*/genetics
Proto-Oncogene Proteins c-akt*/metabolism
Adaptor Proteins, Signal Transducing*/genetics
Adaptor Proteins, Signal Transducing*/metabolism
Humans ; Carcinogenesis ; Cell Transformation, Neoplastic ; Mechanistic Target of Rapamycin Complex 2/genetics ; Mechanistic Target of Rapamycin Complex 2/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
Single-cell transcriptomics implicates the FEZ1-DKK1 axis in the regulation of corneal epithelial cell proliferation and senescence.
Autorzy:
Zhu L; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Wang L; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Liu D; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Chen C; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Mo K; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Lan X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Liu J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Huang Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Guo D; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Huang H; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Li M; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Guo H; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Tan J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Zhang K; Center for Biomedicine and Innovations, Faculty of Medicine, Macau University of Science and Technology, China.
Ji J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Yuan J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
Ouyang H; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science|, Guangzhou, China.
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Źródło:
Cell proliferation [Cell Prolif] 2023 Sep; Vol. 56 (9), pp. e13433. Date of Electronic Publication: 2023 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Corneal Injuries*/metabolism
Transcriptome*
Limbal Stem Cells*/metabolism
Intercellular Signaling Peptides and Proteins*/genetics
Intercellular Signaling Peptides and Proteins*/metabolism
Nerve Tissue Proteins*/genetics
Nerve Tissue Proteins*/metabolism
Adaptor Proteins, Signal Transducing*/genetics
Adaptor Proteins, Signal Transducing*/metabolism
Animals ; Mice ; Cell Proliferation
Czasopismo naukowe
Tytuł:
A genome-wide genetic screen uncovers determinants of human pigmentation.
Autorzy:
Bajpai VK; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; School of Chemical, Biological, and Materials Engineering, The University of Oklahoma, Norman, OK 73019, USA.
Swigut T; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Mohammed J; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Naqvi S; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Genetics, Stanford University, Stanford, CA 94305, USA.
Arreola M; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Tycko J; Department of Genetics, Stanford University, Stanford, CA 94305, USA.
Kim TC; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Pritchard JK; Department of Genetics, Stanford University, Stanford, CA 94305, USA.; Department of Biology, Stanford University, Stanford, CA 94305, USA.
Bassik MC; Department of Genetics, Stanford University, Stanford, CA 94305, USA.; Chemistry, Engineering, and Medicine for Human Health (ChEM-H), Stanford University, Stanford, CA 94305, USA.; Program in Cancer Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Wysocka J; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Aug 11; Vol. 381 (6658), pp. eade6289. Date of Electronic Publication: 2023 Aug 11.
Typ publikacji:
Journal Article
MeSH Terms:
Melanins*/biosynthesis
Melanins*/genetics
Melanocytes*/metabolism
Melanosomes*/metabolism
Skin Pigmentation*/genetics
Adaptor Proteins, Signal Transducing*/genetics
Adaptor Proteins, Signal Transducing*/metabolism
Kruppel-Like Factor 6*/genetics
Kruppel-Like Factor 6*/metabolism
Humans ; Genome-Wide Association Study ; Endosomes/metabolism ; Animals ; Mice ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
An adhesion signaling axis involving Dystroglycan, β1-Integrin, and Cas adaptor proteins regulates the establishment of the cortical glial scaffold.
Autorzy:
Wong W; Neuroscience Graduate Program, University of California, Riverside, California, United States of America.
Estep JA; Cell, Molecular and Developmental Biology Graduate Program, Department of Molecular, Cell & Systems Biology, University of California, Riverside, California, United States of America.
Treptow AM; Cell, Molecular and Developmental Biology Graduate Program, Department of Molecular, Cell & Systems Biology, University of California, Riverside, California, United States of America.
Rajabli N; Cell, Molecular and Developmental Biology Graduate Program, Department of Molecular, Cell & Systems Biology, University of California, Riverside, California, United States of America.
Jahncke JN; Neuroscience Graduate Program, Vollum Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
Ubina T; Neuroscience Graduate Program, University of California, Riverside, California, United States of America.
Wright KM; Neuroscience Graduate Program, Vollum Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
Riccomagno MM; Neuroscience Graduate Program, University of California, Riverside, California, United States of America.; Cell, Molecular and Developmental Biology Graduate Program, Department of Molecular, Cell & Systems Biology, University of California, Riverside, California, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2023 Aug 04; Vol. 21 (8), pp. e3002212. Date of Electronic Publication: 2023 Aug 04 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Adaptor Proteins, Signal Transducing*/genetics
Adaptor Proteins, Signal Transducing*/metabolism
Dystroglycans*/genetics
Dystroglycans*/metabolism
Integrin beta1*/genetics
Integrin beta1*/metabolism
Neuroglia*/metabolism
Animals ; Mice ; Cell Movement/physiology ; Cerebral Cortex/metabolism ; Neurons/physiology ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł:
The Physiological Function of nNOS-Associated CAPON Proteins and the Roles of CAPON in Diseases.
Autorzy:
Xie W; Anti-Aging & Regenerative Medicine Research Institution, School of Life Sciences and Medicine, Shandong University of Technology, Zibo 255049, China.
Xing N; Anti-Aging & Regenerative Medicine Research Institution, School of Life Sciences and Medicine, Shandong University of Technology, Zibo 255049, China.
Qu J; Anti-Aging & Regenerative Medicine Research Institution, School of Life Sciences and Medicine, Shandong University of Technology, Zibo 255049, China.
Liu D; Anti-Aging & Regenerative Medicine Research Institution, School of Life Sciences and Medicine, Shandong University of Technology, Zibo 255049, China.
Pang Q; Anti-Aging & Regenerative Medicine Research Institution, School of Life Sciences and Medicine, Shandong University of Technology, Zibo 255049, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 31; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Adaptor Proteins, Signal Transducing*/metabolism
Signal Transduction*
Humans ; Nitric Oxide Synthase Type I/metabolism
Czasopismo naukowe
Tytuł:
Hypoxia-induced AFAP1L1 regulates pathological neovascularization via the YAP-DLL4-NOTCH axis.
Autorzy:
Ren JS; Department of Ophthalmology, The Affiliated Eye Hospital, Nanjing Medical University, #138 Han-ZhongRoad, Nanjing, 210000, China.; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China.
Bai W; Department of Ophthalmology, The Affiliated Eye Hospital, Nanjing Medical University, #138 Han-ZhongRoad, Nanjing, 210000, China.; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China.
Ding JJ; Department of Ophthalmology, Xuzhou Central Hospital, Xuzhou, 221000, China.
Ge HM; Department of Ophthalmology, The Affiliated Eye Hospital, Nanjing Medical University, #138 Han-ZhongRoad, Nanjing, 210000, China.
Wang SY; Department of Ophthalmology, The Affiliated Eye Hospital, Nanjing Medical University, #138 Han-ZhongRoad, Nanjing, 210000, China.; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China.
Chen X; Department of Ophthalmology, The Affiliated Eye Hospital, Nanjing Medical University, #138 Han-ZhongRoad, Nanjing, 210000, China.; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China.; Department of Ophthalmology, Northern Jiangsu People's Hospital, Yangzhou, 225000, China.
Jiang Q; Department of Ophthalmology, The Affiliated Eye Hospital, Nanjing Medical University, #138 Han-ZhongRoad, Nanjing, 210000, China. .; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Sep 22; Vol. 21 (1), pp. 651. Date of Electronic Publication: 2023 Sep 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adaptor Proteins, Signal Transducing*
Endothelial Cells*
Neovascularization, Pathologic*
Humans ; Angiogenesis Inhibitors ; Calcium-Binding Proteins ; Signal Transduction ; Vascular Endothelial Growth Factor A ; Animals
Czasopismo naukowe
Tytuł:
Genetic associations of TMEM154, PRC1 and ZFAND6 loci with type 2 diabetes in an endogamous business community of North India.
Autorzy:
Walia GK; Public Health Foundation of India, Gurugram, India.; Centre for Chronic Disease Control, Safdarjung Development Area, New Delhi, India.
Sharma P; Indian Institute of Public Health-Delhi, Public Health Foundation of India, Gurugram, India.
Agarwal T; Indian Institute of Public Health-Delhi, Public Health Foundation of India, Gurugram, India.
Lal M; Department of Anthropology, University of Delhi, Delhi, India.
Negandhi H; Public Health Foundation of India, Gurugram, India.
Prabhakaran D; Public Health Foundation of India, Gurugram, India.; Centre for Chronic Disease Control, Safdarjung Development Area, New Delhi, India.
Khadgawat R; Department of Endocrinology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Sachdeva MP; Department of Anthropology, University of Delhi, Delhi, India.
Gupta V; Department of Anthropology, University of Delhi, Delhi, India.
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Źródło:
PloS one [PLoS One] 2023 Sep 22; Vol. 18 (9), pp. e0291339. Date of Electronic Publication: 2023 Sep 22 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Cycle Proteins*/genetics
Diabetes Mellitus, Type 2*/genetics
Membrane Proteins*/genetics
Adaptor Proteins, Signal Transducing*/genetics
Humans ; Asian People/genetics ; Commerce ; Glucose ; India
Czasopismo naukowe
Tytuł:
An association study of cyclase-associated protein 2 and frailty.
Autorzy:
Pelucchi S; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, Milan, Italy.
Macchi C; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, Milan, Italy.
D'Andrea L; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, Milan, Italy.
Rossi PD; Geriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; General Medicine, Hospital San Leopoldo Mandic, Merate, Italy.
Speciani MC; Department of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology 'G.A. Maccacaro', Università degli Studi di Milano, Milan, Italy.
Stringhi R; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, Milan, Italy.
Ruscica M; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, Milan, Italy.; Department of Cardio-Thoracic-Vascular Diseases, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
Arosio B; Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Di Luca M; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, Milan, Italy.
Cesari M; Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Edefonti V; Department of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology 'G.A. Maccacaro', Università degli Studi di Milano, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Marcello E; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, Milan, Italy.
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Źródło:
Aging cell [Aging Cell] 2023 Sep; Vol. 22 (9), pp. e13918. Date of Electronic Publication: 2023 Aug 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Frailty*/blood
Membrane Proteins*/blood
Adaptor Proteins, Signal Transducing*/blood
Aged ; Humans ; Biomarkers/blood ; Cross-Sectional Studies ; Frail Elderly ; Geriatric Assessment/methods ; Independent Living
Czasopismo naukowe
Tytuł:
New insights into the ambivalent role of YAP/TAZ in human cancers.
Autorzy:
Luo J; Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-sen University, No. 628 Zhenyuan Road, Shenzhen, 518107, Guangdong, People's Republic of China.
Deng L; Department of General Surgery, The Seventh Affiliated Hospital of Sun Yat-sen University, No. 628 Zhenyuan Road, Shenzhen, 518107, Guangdong, People's Republic of China.
Zou H; Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-sen University, No. 628 Zhenyuan Road, Shenzhen, 518107, Guangdong, People's Republic of China.
Guo Y; Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-sen University, No. 628 Zhenyuan Road, Shenzhen, 518107, Guangdong, People's Republic of China.
Tong T; Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-sen University, No. 628 Zhenyuan Road, Shenzhen, 518107, Guangdong, People's Republic of China.; Department of Urology, Pelvic Floor Disorders Center, The Seventh Affiliated Hospital of Sun Yat-sen University, No. 628 Zhenyuan Road, Shenzhen, 518107, Guangdong, People's Republic of China.
Huang M; Department of General Surgery, The Seventh Affiliated Hospital of Sun Yat-sen University, No. 628 Zhenyuan Road, Shenzhen, 518107, Guangdong, People's Republic of China.
Ling G; Department of Neurosurgery, The Seventh Affiliated Hospital of Sun Yat-sen University, No. 628 Zhenyuan Road, Shenzhen, 518107, Guangdong, People's Republic of China.
Li P; Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-sen University, No. 628 Zhenyuan Road, Shenzhen, 518107, Guangdong, People's Republic of China. .; Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital of Sun Yat-sen University, No. 628 Zhenyuan Road, Shenzhen, 518107, Guangdong, People's Republic of China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 May 22; Vol. 42 (1), pp. 130. Date of Electronic Publication: 2023 May 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Adaptor Proteins, Signal Transducing*/genetics
Adaptor Proteins, Signal Transducing*/metabolism
Neoplasms*/pathology
Transcriptional Coactivator with PDZ-Binding Motif Proteins*
YAP-Signaling Proteins*
Humans ; Phosphoproteins/metabolism ; Protein Serine-Threonine Kinases/metabolism ; Signal Transduction ; Trans-Activators/metabolism
Czasopismo naukowe
Tytuł:
Ufmylation of UFBP1 Is Dispensable for Endoplasmic Reticulum Stress Response, Embryonic Development, and Cardiac and Intestinal Homeostasis.
Autorzy:
Tandra V; Vascular Biology Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Anderson T; Vascular Biology Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Ayala JD; Vascular Biology Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Weintraub NL; Vascular Biology Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.; Division of Cardiology, Department of Medicine, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Singh N; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Li H; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Li J; Vascular Biology Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.; Division of Cardiology, Department of Medicine, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
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Źródło:
Cells [Cells] 2023 Jul 25; Vol. 12 (15). Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Fibroblasts*
Lysine*
Adaptor Proteins, Signal Transducing*/metabolism
Animals ; Mice ; Embryonic Development ; Endoplasmic Reticulum Stress/physiology ; Homeostasis
Czasopismo naukowe
Tytuł:
Targeted Disruption of the MORG1 Gene in Mice Causes Embryonic Resorption in Early Phase of Development.
Autorzy:
Wulf S; Department of Internal Medicine III, Jena University Hospital, 07747 Jena, Germany.
Mizko L; Department of Internal Medicine III, Jena University Hospital, 07747 Jena, Germany.
Herrmann KH; Medical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, 07747 Jena, Germany.
Sánchez-Carbonell M; Department of Neurology, Jena University Hospital, 07747 Jena, Germany.
Urbach A; Department of Neurology, Jena University Hospital, 07747 Jena, Germany.
Lemke C; Institute for Anatomy I, Jena University Hospital, 07743 Jena, Germany.
Berndt A; Institute of Forensic Medicine, Section Pathology, Jena University Hospital, 07743 Jena, Germany.
Loeffler I; Department of Internal Medicine III, Jena University Hospital, 07747 Jena, Germany.
Wolf G; Department of Internal Medicine III, Jena University Hospital, 07747 Jena, Germany.
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Źródło:
Biomolecules [Biomolecules] 2023 Jun 24; Vol. 13 (7). Date of Electronic Publication: 2023 Jun 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adaptor Proteins, Signal Transducing*/metabolism
Placenta*/metabolism
Animals ; Female ; Mice ; Pregnancy ; Brain/metabolism ; Mice, Knockout ; Signal Transduction
Czasopismo naukowe
Tytuł:
High VEGF Concentrations Accelerate Human Trabecular Meshwork Fibrosis in a TAZ-Dependent Manner.
Autorzy:
Sung MS; Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwangju 61469, Republic of Korea.
Kim SY; Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwangju 61469, Republic of Korea.
Eom GH; Department of Pharmacology, Chonnam National University Medical School, Hwasun 58128, Republic of Korea.
Park SW; Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwangju 61469, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 01; Vol. 24 (11). Date of Electronic Publication: 2023 Jun 01.
Typ publikacji:
Journal Article
MeSH Terms:
Adaptor Proteins, Signal Transducing*/metabolism
Trabecular Meshwork*/metabolism
Vascular Endothelial Growth Factor A*/metabolism
Humans ; Actins/metabolism ; Cells, Cultured ; Extracellular Matrix Proteins/metabolism ; Fibrosis ; Intracellular Signaling Peptides and Proteins/metabolism ; Trans-Activators/metabolism ; Transcription Factors/metabolism ; Transcriptional Coactivator with PDZ-Binding Motif Proteins ; YAP-Signaling Proteins
Czasopismo naukowe