Temat: "Adenovirus E3 Proteins" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Human Adenovirus Type 5 Infection Leads to Nuclear Envelope Destabilization and Membrane Permeability Independently of Adenovirus Death Protein.
Autorzy:: Pfitzner S; Leibniz Institute for Experimental Virology (HPI), Martinistraße 52, 20251 Hamburg, Germany.; Centre for Structural Systems Biology, Notkestraße 85, 22607 Hamburg, Germany.
Bosse JB; Leibniz Institute for Experimental Virology (HPI), Martinistraße 52, 20251 Hamburg, Germany.; Centre for Structural Systems Biology, Notkestraße 85, 22607 Hamburg, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.; Hannover Medical School, Institute of Virology, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
Hofmann-Sieber H; Leibniz Institute for Experimental Virology (HPI), Martinistraße 52, 20251 Hamburg, Germany.
Flomm F; Leibniz Institute for Experimental Virology (HPI), Martinistraße 52, 20251 Hamburg, Germany.; Centre for Structural Systems Biology, Notkestraße 85, 22607 Hamburg, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.; Hannover Medical School, Institute of Virology, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
Reimer R; Leibniz Institute for Experimental Virology (HPI), Martinistraße 52, 20251 Hamburg, Germany.
Dobner T; Leibniz Institute for Experimental Virology (HPI), Martinistraße 52, 20251 Hamburg, Germany.
Grünewald K; Leibniz Institute for Experimental Virology (HPI), Martinistraße 52, 20251 Hamburg, Germany.; Centre for Structural Systems Biology, Notkestraße 85, 22607 Hamburg, Germany.; Universität Hamburg, Institute for Biochemistry and Molecular Biology, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany.
Franken LE; Leibniz Institute for Experimental Virology (HPI), Martinistraße 52, 20251 Hamburg, Germany.; Centre for Structural Systems Biology, Notkestraße 85, 22607 Hamburg, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 02; Vol. 22 (23). Date of Electronic Publication: 2021 Dec 02.
Typ publikacji:: Journal Article
MeSH Terms:: Adenovirus E3 Proteins/*metabolism
Adenoviruses, Human/*metabolism
Nuclear Envelope/*metabolism
Adenovirus E3 Proteins/genetics ; Cell Line, Tumor ; Humans ; Lamin Type A/metabolism ; Microscopy, Electron, Scanning ; Permeability

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Skocz do pozycji: 2.

Tytuł:: RID: Evaluation of the Possible Inhibiting Effect of the Proinflammatory Signaling Induced by TNF- α through NF- κβ and AP-1 in Two Cell Lines of Breast Cancer.
Autorzy:: Monsalve FA; Department of Basic Biomedical Sciences, Faculty of Health Sciences, University of Talca, Chile.
Rojas A; Laboratories of Biomedical Research, Division of Medicine, Universidad Católica del Maule, Chile.
Gonzalez I; Laboratories of Biomedical Research, Division of Medicine, Universidad Católica del Maule, Chile.
Perez R; Laboratories of Biomedical Research, Division of Medicine, Universidad Católica del Maule, Chile.
Añasco C; Laboratories of Biomedical Research, Division of Medicine, Universidad Católica del Maule, Chile.
Romero J; Laboratories of Biomedical Research, Division of Medicine, Universidad Católica del Maule, Chile.
Araya P; Laboratories of Biomedical Research, Division of Medicine, Universidad Católica del Maule, Chile.
Santos LS; Laboratory of Asymmetric Synthesis, Institute of Chemistry and Natural Products, University of Talca, Chile.
Delgado-Lopez F; Laboratories of Biomedical Research, Division of Medicine, Universidad Católica del Maule, Chile.; Pokaż więcej
Źródło:: Mediators of inflammation [Mediators Inflamm] 2020 Jun 22; Vol. 2020, pp. 2707635. Date of Electronic Publication: 2020 Jun 22 (Print Publication: 2020).
Typ publikacji:: Journal Article
MeSH Terms:: Adenovirus E3 Proteins/*physiology
Breast Neoplasms/*metabolism
Membrane Proteins/*physiology
NF-kappa B/*metabolism
Transcription Factor AP-1/*metabolism
Tumor Necrosis Factor-alpha/*pharmacology
Adenoviridae/genetics ; Adenovirus E3 Proteins/genetics ; Cell Line, Tumor ; ErbB Receptors/metabolism ; Humans ; MCF-7 Cells ; Membrane Proteins/genetics ; Receptors, Tumor Necrosis Factor/metabolism ; Signal Transduction/drug effects ; fas Receptor/metabolism

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Skocz do pozycji: 3.

Tytuł:: Molecular Characterization of Hemorrhagic Enteritis Virus (HEV) Obtained from Clinical Samples in Western Canada 2017-2018.
Autorzy:: Palomino-Tapia V; Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Health Research Innovation Center 2C53, 3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada.
Mitevski D; Poultry Health Services, 1-4 East Lake Ave NE, Airdrie, AB T4A 2G8, Canada.
Inglis T; The Institute of Applied Poultry Technologies, 201-151 East Lake Blvd, Airdrie, AB T4A 2G1, Canada.
van der Meer F; Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Health Research Innovation Center 2C53, 3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada.
Abdul-Careem MF; Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Health Research Innovation Center 2C53, 3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada.; Pokaż więcej
Źródło:: Viruses [Viruses] 2020 Aug 26; Vol. 12 (9). Date of Electronic Publication: 2020 Aug 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genome, Viral*
Adenoviridae Infections/*veterinary
Poultry Diseases/*virology
Siadenovirus/*genetics
Turkeys/*virology
Adenoviridae Infections/epidemiology ; Adenoviridae Infections/virology ; Adenovirus E3 Proteins/chemistry ; Adenovirus E3 Proteins/genetics ; Adenovirus Vaccines/immunology ; Animals ; Canada/epidemiology ; Capsid Proteins/chemistry ; Capsid Proteins/genetics ; Genes, Viral ; Glycosylation ; Mutation ; Open Reading Frames ; Siadenovirus/immunology ; Siadenovirus/isolation & purification ; Siadenovirus/pathogenicity ; Spleen/virology ; Viral Proteins/genetics ; Virulence Factors/genetics ; Whole Genome Sequencing

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Skocz do pozycji: 4.

Tytuł:: Adenovirus early region 3 RIDα protein limits NFκB signaling through stress-activated EGF receptors.
Autorzy:: Zeng X; Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University, Cleveland, United States of America.
Carlin CR; Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University, Cleveland, United States of America.; Case Comprehensive Cancer Center, School of Medicine, Case Western Reserve University, Cleveland, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2019 Aug 19; Vol. 15 (8), pp. e1008017. Date of Electronic Publication: 2019 Aug 19 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Stress, Physiological*
Adenovirus E3 Proteins/*metabolism
Adenovirus Infections, Human/*metabolism
Adenoviruses, Human/*physiology
Lysosomes/*metabolism
Membrane Proteins/*metabolism
NF-kappa B/*metabolism
A549 Cells ; Adenovirus Infections, Human/virology ; ErbB Receptors/metabolism ; Humans ; Phosphorylation ; Protein Transport ; Signal Transduction ; Virus Internalization

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Skocz do pozycji: 5.

Tytuł:: Crystal structure of adenovirus E3-19K bound to HLA-A2 reveals mechanism for immunomodulation.
Autorzy:: Li L; Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, Illinois USA.
Muzahim Y
Bouvier M; Pokaż więcej
Źródło:: Nature structural & molecular biology [Nat Struct Mol Biol] 2012 Nov; Vol. 19 (11), pp. 1176-81. Date of Electronic Publication: 2012 Oct 07.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Models, Molecular*
Protein Conformation*
Adenovirus E3 Proteins/*chemistry
Adenovirus E3 Proteins/*immunology
HLA-A2 Antigen/*chemistry
Immunomodulation/*immunology
T-Lymphocytes/*immunology
Adenovirus E3 Proteins/metabolism ; Cloning, Molecular ; Crystallography ; Endoplasmic Reticulum/metabolism ; Escherichia coli ; HLA-A2 Antigen/metabolism ; Humans ; Immunomodulation/genetics ; Protein Binding

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Skocz do pozycji: 6.

Tytuł:: E3-14.7K is recruited to TNF-receptor 1 and blocks TNF cytolysis independent from interaction with optineurin.
Autorzy:: Klingseisen L; Institute for Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.
Ehrenschwender M
Heigl U
Wajant H
Hehlgans T
Schütze S
Schneider-Brachert W; Pokaż więcej
Źródło:: PloS one [PLoS One] 2012; Vol. 7 (6), pp. e38348. Date of Electronic Publication: 2012 Jun 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenovirus E3 Proteins/*metabolism
Receptors, Tumor Necrosis Factor, Type I/*metabolism
Transcription Factor TFIIIA/*metabolism
Tumor Necrosis Factor-alpha/*pharmacology
Adenovirus E3 Proteins/chemistry ; Adenovirus E3 Proteins/genetics ; Amino Acid Sequence ; Cell Cycle Proteins ; Cell Death/drug effects ; Cell Line ; Cytoprotection/drug effects ; Endocytosis/drug effects ; Gene Knockdown Techniques ; Humans ; Membrane Transport Proteins ; Molecular Sequence Data ; Mutation/genetics ; NF-kappa B/metabolism ; Protein Binding/drug effects

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Skocz do pozycji: 7.

Tytuł:: No evidence of a death-like function for species B1 human adenovirus type 3 E3-9K during A549 cell line infection.
Autorzy:: Frietze KM; Infectious Disease Program, Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM, USA.
Campos SK
Kajon AE; Pokaż więcej
Źródło:: BMC research notes [BMC Res Notes] 2012 Aug 11; Vol. 5, pp. 429. Date of Electronic Publication: 2012 Aug 11.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenovirus E3 Proteins/*physiology
Adenoviruses, Human/*physiology
Adenovirus E3 Proteins/genetics ; Cell Line, Tumor ; Gene Knockdown Techniques ; Green Fluorescent Proteins/genetics ; Humans ; Mutation ; Open Reading Frames

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Skocz do pozycji: 8.

Tytuł:: Anticancer activity of oncolytic adenovirus vector armed with IFN-alpha and ADP is enhanced by pharmacologically controlled expression of TRAIL.
Autorzy:: Shashkova EV; VirRx Inc., St Louis, MO, USA.
Kuppuswamy MN
Wold WS
Doronin K; Pokaż więcej
Źródło:: Cancer gene therapy [Cancer Gene Ther] 2008 Feb; Vol. 15 (2), pp. 61-72. Date of Electronic Publication: 2007 Nov 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Genetic Therapy*
Genetic Vectors*
Adenoviridae/*genetics
Adenovirus E3 Proteins/*genetics
Interferon-alpha/*genetics
Neoplasms/*therapy
TNF-Related Apoptosis-Inducing Ligand/*biosynthesis
TNF-Related Apoptosis-Inducing Ligand/*genetics
Adenoviridae/physiology ; Adenovirus E3 Proteins/biosynthesis ; Adenovirus E3 Proteins/physiology ; Animals ; Apoptosis/genetics ; Cell Line, Tumor ; Doxycycline/pharmacology ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Expression Regulation, Neoplastic/physiology ; Humans ; Interferon-alpha/biosynthesis ; Interferon-alpha/physiology ; Mice ; Mutation ; Neoplasms/genetics ; Neoplasms/pathology ; TNF-Related Apoptosis-Inducing Ligand/physiology ; Tetracycline/pharmacology

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Skocz do pozycji: 9.

Tytuł:: ADP-overexpressing adenovirus elicits enhanced cytopathic effect by induction of apoptosis.
Autorzy:: Yun CO; Brain Korea 21 Project for Medical Sciences, Institute for Cancer Research, Yonsei Cancer Center, Seoul, Korea. />Kim E
Koo T
Kim H
Lee YS
Kim JH; Pokaż więcej
Źródło:: Cancer gene therapy [Cancer Gene Ther] 2005 Jan; Vol. 12 (1), pp. 61-71.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenoviridae/*genetics
Adenovirus E3 Proteins/*biosynthesis
Adenovirus E3 Proteins/*genetics
Apoptosis/*genetics
Carcinoma, Hepatocellular/*therapy
Genetic Therapy/*methods
Uterine Cervical Neoplasms/*therapy
Adenoviridae/pathogenicity ; Adenovirus E3 Proteins/pharmacology ; Animals ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Drug Screening Assays, Antitumor ; Female ; Fibroblasts ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Liver Neoplasms/therapy ; Male ; Membrane Glycoproteins ; Mice ; Mice, Nude ; RNA, Messenger/analysis ; RNA, Messenger/biosynthesis ; Transplantation, Heterologous ; Tumor Cells, Cultured ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/pathology ; Virus Replication

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Skocz do pozycji: 10.

Tytuł:: Optimization of vaccine responses with an E1, E2b and E3-deleted Ad5 vector circumvents pre-existing anti-vector immunity.
Autorzy:: Osada T; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.
Yang XY
Hartman ZC
Glass O
Hodges BL
Niedzwiecki D
Morse MA
Lyerly HK
Amalfitano A
Clay TM; Pokaż więcej
Źródło:: Cancer gene therapy [Cancer Gene Ther] 2009 Sep; Vol. 16 (9), pp. 673-82. Date of Electronic Publication: 2009 Feb 20.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Adenoviridae/*genetics
Adenoviridae/*immunology
Adenovirus E1 Proteins/*genetics
Adenovirus E2 Proteins/*genetics
Adenovirus E3 Proteins/*genetics
Cancer Vaccines/*immunology
Genetic Vectors/*immunology
Adenovirus E1 Proteins/immunology ; Adenovirus E2 Proteins/immunology ; Adenovirus E3 Proteins/immunology ; Animals ; Antigen Presentation ; Cancer Vaccines/genetics ; Carcinoembryonic Antigen/metabolism ; Cell Differentiation ; Cells, Cultured ; Cytotoxicity, Immunologic ; Dendritic Cells/cytology ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Gene Deletion ; Humans ; Killer Cells, Natural/immunology ; Kinetics ; Mice ; Mice, Inbred C57BL

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Skocz do pozycji: 11.

Tytuł:: Deletion of the E3-6.7K/gp19K region reduces the persistence of wild-type adenovirus in a permissive tumor model in Syrian hamsters.
Autorzy:: Bortolanza S; Division of Hepatology and Gene Therapy, CIMA, Foundation for Applied Medical Research, School of Medicine, University of Navarra, Pamplona 31008, Spain.
Bunuales M
Alzuguren P
Lamas O
Aldabe R
Prieto J
Hernandez-Alcoceba R; Pokaż więcej
Źródło:: Cancer gene therapy [Cancer Gene Ther] 2009 Sep; Vol. 16 (9), pp. 703-12. Date of Electronic Publication: 2009 Feb 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Deletion*
Oncolytic Virotherapy*
Virus Replication*
Adenoviridae/*genetics
Adenovirus E3 Proteins/*genetics
Neoplasms/*immunology
Neoplasms/*therapy
Adenoviridae/physiology ; Adenovirus E3 Proteins/immunology ; Animals ; Cell Line ; Cricetinae ; Disease Models, Animal ; Gene Expression Regulation, Viral ; Genes, Reporter ; Genome, Viral ; Humans ; Immunocompetence ; Mesocricetus ; Mice ; Neoplasms/virology ; Transgenes ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 12.

Tytuł:: E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models.
Autorzy:: Wang Y; Viral and Genetic Therapy Program, Cancer Research UK and Imperial College School of Medicine, Hammersmith Hospital, London, UK.
Hallden G
Hill R
Anand A
Liu TC
Francis J
Brooks G
Lemoine N
Kirn D; Pokaż więcej
Źródło:: Nature biotechnology [Nat Biotechnol] 2003 Nov; Vol. 21 (11), pp. 1328-35. Date of Electronic Publication: 2003 Oct 12.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenoviridae/*growth & development
Adenoviridae/*metabolism
Adenovirus E3 Proteins/*metabolism
Carcinoma/*virology
Immunocompetence/*immunology
Virus Activation/*physiology
Adenoviridae/genetics ; Adenoviridae/immunology ; Adenovirus E3 Proteins/genetics ; Adenovirus E3 Proteins/immunology ; Animals ; Cell Line, Tumor ; Disease Models, Animal ; Mice ; Mice, Nude ; Recombinant Proteins/metabolism

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Skocz do pozycji: 13.

Tytuł:: A novel mechanism of nuclear factor-kappaB regulation by adenoviral protein 14.7K.
Autorzy:: Carmody RJ; Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA.
Maguschak K
Chen YH; Pokaż więcej
Źródło:: Immunology [Immunology] 2006 Feb; Vol. 117 (2), pp. 188-95.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Adenovirus E3 Proteins/*pharmacology
NF-kappa B/*antagonists & inhibitors
Adenovirus E3 Proteins/metabolism ; Animals ; Blotting, Western ; Cells, Cultured ; Cytokines/biosynthesis ; Cytokines/genetics ; DNA-Binding Proteins/metabolism ; I-kappa B Proteins/metabolism ; Mice ; Mice, Inbred C57BL ; NF-KappaB Inhibitor alpha ; NF-kappa B/genetics ; NF-kappa B/metabolism ; NF-kappa B p50 Subunit/metabolism ; Promoter Regions, Genetic ; Receptors, Tumor Necrosis Factor/physiology ; Signal Transduction ; Toll-Like Receptors/physiology ; Transcriptional Activation/drug effects

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Skocz do pozycji: 14.

Tytuł:: Functions and mechanisms of action of the adenovirus E3 proteins.
Autorzy:: Lichtenstein DL; Department of Molecular Microbiology and Immunology, Saint Louis University Health Sciences Center, St. Louis, Missouri 63104, USA.
Toth K
Doronin K
Tollefson AE
Wold WS; Pokaż więcej
Źródło:: International reviews of immunology [Int Rev Immunol] 2004 Jan-Apr; Vol. 23 (1-2), pp. 75-111.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Adenoviridae/*pathogenicity
Adenovirus E3 Proteins/*physiology
Adenoviridae/genetics ; Adenoviridae/physiology ; Adenoviridae Infections/pathology ; Adenoviridae Infections/physiopathology ; Adenoviridae Infections/virology ; Adenovirus E3 Proteins/genetics ; Animals ; Apoptosis/physiology ; Disease Models, Animal ; Genetic Vectors ; Histocompatibility Antigens Class I/metabolism ; Humans ; Mice ; Mice, Transgenic ; Models, Biological ; Transcription, Genetic

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Skocz do pozycji: 15.

Tytuł:: Radiation increases the activity of oncolytic adenovirus cancer gene therapy vectors that overexpress the ADP (E3-11.6K) protein.
Autorzy:: Toth K; Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Missouri 63104, USA. />Tarakanova V
Doronin K
Ward P
Kuppuswamy M
Locke JE
Dawson JE
Kim HJ
Wold WS; Pokaż więcej
Źródło:: Cancer gene therapy [Cancer Gene Ther] 2003 Mar; Vol. 10 (3), pp. 193-200.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Genetic Therapy*
Adenoviridae/*genetics
Adenovirus E3 Proteins/*genetics
Neoplasms, Experimental/*radiotherapy
Neoplasms, Experimental/*therapy
Adenovirus E3 Proteins/metabolism ; Animals ; Cell Line, Tumor ; Combined Modality Therapy ; Dose-Response Relationship, Radiation ; Female ; Genetic Vectors ; Humans ; Lung Neoplasms/therapy ; Mice ; Mice, Nude ; Neoplasms, Experimental/metabolism ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 16.

Tytuł:: Heterologous expression of adenovirus E3-gp19K in an E1a-deleted adenovirus vector inhibits MHC I expression in vitro, but does not prolong transgene expression in vivo.
Autorzy:: Schowalter DB; Department of Internal Medicine, University of Washington, Seattle 98195, USA.
Tubb JC
Liu M
Wilson CB
Kay MA; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 1997 Apr; Vol. 4 (4), pp. 351-60.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Antigen Presentation*
Transgenes*
Adenoviridae/*genetics
Adenovirus E3 Proteins/*genetics
Genes, MHC Class I/*genetics
Genetic Vectors/*genetics
Adenovirus E3 Proteins/metabolism ; Animals ; Gene Expression ; In Situ Hybridization, Fluorescence ; Liver/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Transgenic ; Precipitin Tests

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Skocz do pozycji: 17.

Tytuł:: Insertion of exogenous epitopes in the E3-19K of oncolytic adenoviruses to enhance TAP-independent presentation and immunogenicity.
Autorzy:: Rodríguez-García A; Translational Research Laboratory, IDIBELL-Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
Svensson E; Department of Immunology, Genetics and Pathology, Science for Life Laboratories, Uppsala University, Uppsala, Sweden.
Gil-Hoyos R; Translational Research Laboratory, IDIBELL-Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
Fajardo CA; Translational Research Laboratory, IDIBELL-Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
Rojas LA; Translational Research Laboratory, IDIBELL-Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
Arias-Badia M; Translational Research Laboratory, IDIBELL-Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
Loskog AS; Department of Immunology, Genetics and Pathology, Science for Life Laboratories, Uppsala University, Uppsala, Sweden.
Alemany R; Translational Research Laboratory, IDIBELL-Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.; Pokaż więcej
Źródło:: Gene therapy [Gene Ther] 2015 Jul; Vol. 22 (7), pp. 596-601. Date of Electronic Publication: 2015 May 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mutagenesis, Insertional*
ATP-Binding Cassette Transporters/*metabolism
Adenovirus E3 Proteins/*genetics
Adenoviruses, Human/*genetics
Epitopes/*genetics
Neoplasms/*therapy
Oncolytic Viruses/*genetics
Adenoviruses, Human/metabolism ; Animals ; Antigen Presentation ; Cell Line, Tumor ; Female ; HEK293 Cells ; Humans ; Mice, Inbred C57BL

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Skocz do pozycji: 18.

Tytuł:: Adenovirus vectors lacking virus-associated RNA expression enhance shRNA activity to suppress hepatitis C virus replication.
Autorzy:: Pei Z; Laboratory of Molecular Genetics, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Shi G; Department of Infectious Diseases, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Kondo S; Laboratory of Molecular Genetics, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Ito M; Department of Infectious Diseases, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Maekawa A; Laboratory of Molecular Genetics, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Suzuki M; Laboratory of Molecular Genetics, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Saito I; Laboratory of Molecular Genetics, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.
Suzuki T; Department of Infectious Diseases, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Kanegae Y; Laboratory of Molecular Genetics, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-0071, Japan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2013 Dec 20; Vol. 3, pp. 3575. Date of Electronic Publication: 2013 Dec 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenoviridae/*genetics
Genetic Vectors/*genetics
Hepacivirus/*genetics
Hepatitis C, Chronic/*therapy
Virus Replication/*genetics
Adenovirus E1 Proteins/genetics ; Adenovirus E3 Proteins/genetics ; Adenovirus E4 Proteins/genetics ; Cell Line ; Genetic Therapy ; HEK293 Cells ; Hepacivirus/growth & development ; Hepatitis C, Chronic/genetics ; Humans ; Promoter Regions, Genetic ; RNA Interference ; RNA, Small Interfering ; RNA, Viral/biosynthesis ; Virus Integration/genetics