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Tytuł :
GRK2 levels in myeloid cells modulate adipose-liver crosstalk in high fat diet-induced obesity.
Autorzy :
Vila-Bedmar R; Departamento de ciencias básicas de la salud, área de Bioquímica y Biología Molecular, Universidad Rey Juan Carlos (URJC), Madrid, Spain.
Cruces-Sande M; Departamento de Biología Molecular and Centro de Biología Molecular 'Severo Ochoa', Universidad Autónoma de Madrid (CSIC/UAM), C/Nicolás Cabrera 1, 28049, Madrid, Spain.; Instituto de Investigación Sanitaria La Princesa, Madrid, Spain.; CIBER de Enfermedades Cardiovasculares, Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Arcones AC; Departamento de Biología Molecular and Centro de Biología Molecular 'Severo Ochoa', Universidad Autónoma de Madrid (CSIC/UAM), C/Nicolás Cabrera 1, 28049, Madrid, Spain.; Instituto de Investigación Sanitaria La Princesa, Madrid, Spain.; CIBER de Enfermedades Cardiovasculares, Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Willemen HLDM; Laboratory of Translational Immunology (LTI), University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Prieto P; CIBER de Enfermedades Cardiovasculares, Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Madrid, Spain.
Moreno-Indias I; CIBER de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Instituto de Investigación Biomédica de Málaga (IBIMA), Unidad de Endocrinología y Nutrición, Hospital Universitario Virgen de Victoria de Malaga, Universidad de Málaga, Málaga, Spain.
Díaz-Rodríguez D; Departamento de Biología Molecular and Centro de Biología Molecular 'Severo Ochoa', Universidad Autónoma de Madrid (CSIC/UAM), C/Nicolás Cabrera 1, 28049, Madrid, Spain.
Francisco S; Departamento de Biología Molecular and Centro de Biología Molecular 'Severo Ochoa', Universidad Autónoma de Madrid (CSIC/UAM), C/Nicolás Cabrera 1, 28049, Madrid, Spain.
Jaén RI; Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Madrid, Spain.
Gutiérrez-Repiso C; CIBER de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Instituto de Investigación Biomédica de Málaga (IBIMA), Unidad de Endocrinología y Nutrición, Hospital Universitario Virgen de Victoria de Malaga, Universidad de Málaga, Málaga, Spain.
Heijnen CJ; University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Boscá L; CIBER de Enfermedades Cardiovasculares, Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Madrid, Spain.
Fresno M; Departamento de Biología Molecular and Centro de Biología Molecular 'Severo Ochoa', Universidad Autónoma de Madrid (CSIC/UAM), C/Nicolás Cabrera 1, 28049, Madrid, Spain.; Instituto de Investigación Sanitaria La Princesa, Madrid, Spain.
Kavelaars A; University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Mayor F Jr; Departamento de Biología Molecular and Centro de Biología Molecular 'Severo Ochoa', Universidad Autónoma de Madrid (CSIC/UAM), C/Nicolás Cabrera 1, 28049, Madrid, Spain. .; Instituto de Investigación Sanitaria La Princesa, Madrid, Spain. .; CIBER de Enfermedades Cardiovasculares, Instituto de Salud Carlos III (ISCIII), Madrid, Spain. .
Murga C; Departamento de Biología Molecular and Centro de Biología Molecular 'Severo Ochoa', Universidad Autónoma de Madrid (CSIC/UAM), C/Nicolás Cabrera 1, 28049, Madrid, Spain. .; Instituto de Investigación Sanitaria La Princesa, Madrid, Spain. .; CIBER de Enfermedades Cardiovasculares, Instituto de Salud Carlos III (ISCIII), Madrid, Spain. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Dec; Vol. 77 (23), pp. 4957-4976. Date of Electronic Publication: 2020 Jan 11.
Typ publikacji :
Journal Article
MeSH Terms :
Diet, High-Fat*
Adipose Tissue/*metabolism
G-Protein-Coupled Receptor Kinase 2/*metabolism
Liver/*metabolism
Myeloid Cells/*metabolism
Obesity/*metabolism
Adipocytes/drug effects ; Adipocytes/metabolism ; Adipocytes/pathology ; Adipose Tissue, White/pathology ; Animals ; Culture Media, Conditioned/pharmacology ; Cytoprotection/drug effects ; Fatty Liver/complications ; Fatty Liver/pathology ; Gastrointestinal Microbiome/drug effects ; Glucose/metabolism ; Glucose Intolerance/metabolism ; Hypertrophy ; Inflammation/pathology ; Insulin/metabolism ; Insulin Resistance ; Macrophages, Peritoneal/drug effects ; Macrophages, Peritoneal/metabolism ; Mice, Inbred C57BL ; Models, Biological ; Myeloid Cells/drug effects ; Obesity/complications ; Signal Transduction/drug effects ; Weight Gain/drug effects
Czasopismo naukowe
Tytuł :
Branched-chain Amino Acid Catabolism by Brown Adipose Tissue.
Autorzy :
Carpentier AC; Division of Endocrinology, Department of Medicine, Centre de recherche du CHUS, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
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Źródło :
Endocrinology [Endocrinology] 2020 Jul 01; Vol. 161 (7).
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Adipose Tissue, Brown*
Amino Acids, Branched-Chain*
Adipose Tissue ; Homeostasis
Czasopismo naukowe
Tytuł :
Endocrine Mechanisms Connecting Exercise to Brown Adipose Tissue Metabolism: a Human Perspective.
Autorzy :
Mendez-Gutierrez A; Department of Biochemistry and Molecular Biology II, 'José Mataix Verdú' Institute of Nutrition and Food Technology (INYTA), Biomedical Research Centre (CIBM), University of Granada, Granada, Spain.; Biohealth Research Institute in Granada (ibs.GRANADA), Granada, Spain.; CIBER Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Madrid, Spain.
Osuna-Prieto FJ; Department of Analytical Chemistry, Technology Centre for Functional Food Research and Development (CIDAF), University of Granada, Granada, Spain.; PROFITH 'PROmoting FITness and Health through Physical Activity' Research Group, Sport and Health University Research Institute (iMUDS), Faculty of Sport Sciences, University of Granada, Granada, Spain.
Aguilera CM; Department of Biochemistry and Molecular Biology II, 'José Mataix Verdú' Institute of Nutrition and Food Technology (INYTA), Biomedical Research Centre (CIBM), University of Granada, Granada, Spain.; Biohealth Research Institute in Granada (ibs.GRANADA), Granada, Spain.; CIBER Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Madrid, Spain.
Ruiz JR; PROFITH 'PROmoting FITness and Health through Physical Activity' Research Group, Sport and Health University Research Institute (iMUDS), Faculty of Sport Sciences, University of Granada, Granada, Spain. .; Department of Physical Education and Sports, University of Granada, Granada, Spain. .
Sanchez-Delgado G; PROFITH 'PROmoting FITness and Health through Physical Activity' Research Group, Sport and Health University Research Institute (iMUDS), Faculty of Sport Sciences, University of Granada, Granada, Spain. .; Department of Physical Education and Sports, University of Granada, Granada, Spain. .; Pennington Biomedical Research Center, Baton Rouge, LA, USA. .
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Źródło :
Current diabetes reports [Curr Diab Rep] 2020 Jul 28; Vol. 20 (9), pp. 40. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Adipose Tissue, Brown*
Thermogenesis*
Adipose Tissue, White ; Exercise ; Humans
Czasopismo naukowe
Tytuł :
DUODENAL-JEJUNAL BYPASS REDUCES LIPID ACCUMULATION IN THE BROWN ADIPOSE TISSUE OF HYPOTHALAMIC OBESE RATS.
Autorzy :
Ceglarek VM; Endocrine Physiology and Metabolism Laboratory, Center for Biological and Health Sciences, State University of Western Paraná, Cascavel, PR, Brazil.
Guareschi ZM; Endocrine Physiology and Metabolism Laboratory, Center for Biological and Health Sciences, State University of Western Paraná, Cascavel, PR, Brazil.
Moreira-Soares G; Endocrine Pancreas and Metabolism Laboratory, Department of Structural and Functional Biology, Institute of Biology, Campinas State University, Campinas, SP, Brazil.
Ecker-Passarello RC; Endocrine Physiology and Metabolism Laboratory, Center for Biological and Health Sciences, State University of Western Paraná, Cascavel, PR, Brazil.
Balbo SL; Endocrine Physiology and Metabolism Laboratory, Center for Biological and Health Sciences, State University of Western Paraná, Cascavel, PR, Brazil.
Bonfleur ML; Endocrine Physiology and Metabolism Laboratory, Center for Biological and Health Sciences, State University of Western Paraná, Cascavel, PR, Brazil.
Grassiolli S; Endocrine Physiology and Metabolism Laboratory, Center for Biological and Health Sciences, State University of Western Paraná, Cascavel, PR, Brazil.
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Źródło :
Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery [Arq Bras Cir Dig] 2020 Jul 08; Vol. 33 (1), pp. e1497.
Typ publikacji :
Journal Article
MeSH Terms :
Adipose Tissue, Brown*
Gastric Bypass*
Adipose Tissue ; Animals ; Blood Glucose ; Duodenum ; Lipids ; Male ; Obesity ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Adipose Tissue in Multiple Symmetric Lipomatosis Shows Features of Brown/Beige Fat.
Autorzy :
Schiltz D; Department of Plastic, Hand- and Reconstructive Surgery, University Medical Center, Regensburg, Germany.
Tschernitz S; Department of Dermatology, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany.
Ortner C; Department of Dermatology, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany.
Anker A; Department of Plastic, Hand- and Reconstructive Surgery, University Medical Center, Regensburg, Germany.
Klein S; Department of Plastic, Hand- and Reconstructive Surgery, University Medical Center, Regensburg, Germany.
Felthaus O; Department of Plastic, Hand- and Reconstructive Surgery, University Medical Center, Regensburg, Germany.
Biermann N; Department of Plastic, Hand- and Reconstructive Surgery, University Medical Center, Regensburg, Germany.
Schreml J; Institute of Human Genetics, University Hospital of Cologne, Cologne, Germany.
Prantl L; Department of Plastic, Hand- and Reconstructive Surgery, University Medical Center, Regensburg, Germany.
Schreml S; Department of Dermatology, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany. .
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Źródło :
Aesthetic plastic surgery [Aesthetic Plast Surg] 2020 Jun; Vol. 44 (3), pp. 855-861. Date of Electronic Publication: 2020 Mar 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipose Tissue, Beige*
Lipomatosis, Multiple Symmetrical*/surgery
Adipose Tissue ; Humans
Czasopismo naukowe
Tytuł :
Single cell approaches to address adipose tissue stromal cell heterogeneity.
Autorzy :
Rondini EA; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, U.S.A.; Center for Integrative Metabolic and Endocrine Research, Wayne State University, Detroit, MI, U.S.A.
Granneman JG; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, U.S.A.; Center for Integrative Metabolic and Endocrine Research, Wayne State University, Detroit, MI, U.S.A.
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Źródło :
The Biochemical journal [Biochem J] 2020 Feb 14; Vol. 477 (3), pp. 583-600.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Adipose Tissue, White*/cytology
Adipose Tissue, White*/immunology
Adipose Tissue, White*/metabolism
Adipocytes/*metabolism
Macrophages/*metabolism
Stromal Cells/*cytology
Adipocytes/immunology ; Adipose Tissue/cytology ; Adipose Tissue/immunology ; Adipose Tissue/metabolism ; Animals ; Cell Communication ; Flow Cytometry ; Humans ; Macrophages/cytology ; Obesity/metabolism ; Obesity/therapy ; Sequence Analysis, RNA ; Single-Cell Analysis ; Stromal Cells/metabolism ; Stromal Cells/pathology
Czasopismo naukowe
Tytuł :
Adipose depot-specific upregulation of Ucp1 or mitochondrial oxidative complex proteins are early consequences of genetic insulin reduction in mice.
Autorzy :
Botezelli JD; Department of Cellular Physiological Sciences, Diabetes Research group, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.; Laboratory of Molecular Biology of Exercise (LaBMEx), Faculty of Applied Sciences, University of Campinas, Limeira, São Paulo, Brazil.
Overby P; Department of Cellular Physiological Sciences, Diabetes Research group, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Lindo L; Department of Cellular Physiological Sciences, Diabetes Research group, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Wang S; Department of Cellular Physiological Sciences, Diabetes Research group, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Haïda O; Department of Cellular Physiological Sciences, Diabetes Research group, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Lim GE; Cardiometabolic axis, Centre de recherche du Centre hospitalier de l'Université de Montréal, Université of Montréal, Montréal, Quebec, Canada.
Templeman NM; Princeton University, Princeton, New Jersey.
Pauli JR; Laboratory of Molecular Biology of Exercise (LaBMEx), Faculty of Applied Sciences, University of Campinas, Limeira, São Paulo, Brazil.
Johnson JD; Department of Cellular Physiological Sciences, Diabetes Research group, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.
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Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2020 Sep 01; Vol. 319 (3), pp. E529-E539. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipose Tissue/*metabolism
Insulin/*genetics
Insulin/*metabolism
Mitochondria/*metabolism
Uncoupling Protein 1/*biosynthesis
3T3-L1 Cells ; Adipose Tissue, Brown/metabolism ; Adipose Tissue, White/metabolism ; Animals ; Blood Glucose/metabolism ; Body Weight/genetics ; Diet, High-Fat ; Hyperinsulinism/genetics ; Hyperinsulinism/metabolism ; Mice ; Mice, Knockout ; Oxidative Phosphorylation ; Oxygen Consumption ; Up-Regulation
Czasopismo naukowe
Tytuł :
[Research and thinking of acupuncture on promoting white adipose tissue browning].
Autorzy :
Jing XY; Key Laboratory of Integration of Acupuncture and Medication of the Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Hong H; Key Laboratory of Integration of Acupuncture and Medication of the Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Zhu BM; Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu 610041.
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Źródło :
Zhen ci yan jiu = Acupuncture research [Zhen Ci Yan Jiu] 2020 Mar 25; Vol. 45 (3), pp. 251-4.
Typ publikacji :
Journal Article
MeSH Terms :
Acupuncture Therapy*
Adipose Tissue, Brown*
Adipose Tissue, White ; Energy Metabolism ; Humans ; Obesity
Czasopismo naukowe
Tytuł :
Exploring Adipose Tissue Structure by Methylsalicylate Clearing and 3D Imaging.
Autorzy :
Gilleron J; Université Côte d'Azur, Inserm UMR1065, C3M, Team 'Cellular and Molecular Pathophysiology of Obesity', Nice, France; .
Meziat C; Université Côte d'Azur, Inserm UMR1065, C3M, Team 'Cellular and Molecular Pathophysiology of Obesity', Nice, France.
Sulen A; Integrated Cardio Metabolic Center, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Ivanov S; Université Côte d'Azur, Inserm UMR1065, C3M, Team 'Haematometabolism in Diseases', Nice, France.
Jager J; Université Côte d'Azur, Inserm UMR1065, C3M, Team 'Cellular and Molecular Pathophysiology of Obesity', Nice, France.
Estève D; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.
Muller C; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.
Tanti JF; Université Côte d'Azur, Inserm UMR1065, C3M, Team 'Cellular and Molecular Pathophysiology of Obesity', Nice, France.
Cormont M; Université Côte d'Azur, Inserm UMR1065, C3M, Team 'Cellular and Molecular Pathophysiology of Obesity', Nice, France.
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2020 Aug 19 (162). Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Imaging, Three-Dimensional*
Adipose Tissue/*pathology
Salicylates/*pharmacokinetics
Adipocytes/metabolism ; Adipocytes/pathology ; Adipose Tissue/metabolism ; Adipose Tissue, White/metabolism ; Adipose Tissue, White/pathology ; Animals ; Humans ; Mice ; Microscopy, Fluorescence ; Obesity/metabolism ; Obesity/pathology
Czasopismo naukowe
Tytuł :
Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age.
Autorzy :
Brigger D; Department of Rheumatology, Immunology and Allergology, Bern University Hospital, University of Bern, Bern, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland.
Riether C; Tumor Immunology, Department for BioMedical Reserach, University of Bern, Bern, Switzerland.; Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
van Brummelen R; Department of Rheumatology, Immunology and Allergology, Bern University Hospital, University of Bern, Bern, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland.
Mosher KI; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.; Department of Chemical and Biological Engineering, University of California, Berkeley, CA, USA.
Shiu A; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.; Amplitude Analytics Inc., San Francisco, CA, USA.
Ding Z; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.; Johnson & Johnson Pharmaceutical Research & Development, L.L.C., San Diego, CA, USA.
Zbären N; Department of Rheumatology, Immunology and Allergology, Bern University Hospital, University of Bern, Bern, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland.
Gasser P; Department of Rheumatology, Immunology and Allergology, Bern University Hospital, University of Bern, Bern, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland.
Guntern P; Department of Rheumatology, Immunology and Allergology, Bern University Hospital, University of Bern, Bern, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland.
Yousef H; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Castellano JM; Nash Family Department of Neuroscience, Department of Neurology, Friedman Brain Institute, Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Storni F; Department of Rheumatology, Immunology and Allergology, Bern University Hospital, University of Bern, Bern, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland.; Department for Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Graff-Radford N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
Britschgi M; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.; Roche Pharma Research and Early Development, Neuroscience Discovery, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
Grandgirard D; Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
Hinterbrandner M; Tumor Immunology, Department for BioMedical Reserach, University of Bern, Bern, Switzerland.; Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Siegrist M; Department for BioMedical Research, University of Bern, Bern, Switzerland.
Moullan N; Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Hofstetter W; Department for BioMedical Research, University of Bern, Bern, Switzerland.
Leib SL; Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
Villiger PM; Department of Rheumatology, Immunology and Allergology, Bern University Hospital, University of Bern, Bern, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland.
Auwerx J; Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Villeda SA; Department of Anatomy, University of California San Francisco, San Francisco, CA, USA.
Wyss-Coray T; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.
Noti M; Institute of Pathology, Division of Experimental Pathology, University of Bern, Bern, Switzerland. .; Department of Gastrointestinal Health, Immunology, Nestlé Research, Lausanne, Switzerland. .
Eggel A; Department of Rheumatology, Immunology and Allergology, Bern University Hospital, University of Bern, Bern, Switzerland. .; Department for BioMedical Research, University of Bern, Bern, Switzerland. .
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Źródło :
Nature metabolism [Nat Metab] 2020 Aug; Vol. 2 (8), pp. 688-702. Date of Electronic Publication: 2020 Jul 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Immunity*
Adipose Tissue/*physiology
Eosinophils/*physiology
Inflammation/*pathology
Physical Fitness/*physiology
Adipose Tissue/pathology ; Adipose Tissue, White/pathology ; Adipose Tissue, White/physiology ; Adult ; Aged ; Aging ; Animals ; Eosinophils/immunology ; Eosinophils/pathology ; Gene Expression Regulation ; Glucose Tolerance Test ; Homeostasis ; Humans ; Interleukin-4/immunology ; Interleukin-4/physiology ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Muscle Strength ; Satellite Cells, Skeletal Muscle/metabolism ; Young Adult
Czasopismo naukowe
Tytuł :
Identification and characterization of adipose surface epitopes.
Autorzy :
Onogi Y; RG Adipocytes and Metabolism, Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, 85764 Neuherberg, Germany.; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.
Khalil AEMM; RG Adipocytes and Metabolism, Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, 85764 Neuherberg, Germany.; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.
Ussar S; RG Adipocytes and Metabolism, Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, 85764 Neuherberg, Germany.; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.; Department of Medicine, Technische Universität München, Munich, Germany.
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Źródło :
The Biochemical journal [Biochem J] 2020 Jul 17; Vol. 477 (13), pp. 2509-2541.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Adipose Tissue/*metabolism
Epitopes/*immunology
Adipocytes/cytology ; Adipocytes/metabolism ; Adipogenesis/physiology ; Adipose Tissue, Brown/metabolism ; Adipose Tissue, White/metabolism ; Animals ; Humans ; Insulin Resistance/physiology
Czasopismo naukowe
Tytuł :
Ambient fine particulate matter exposure perturbed circadian rhythm and oscillations of lipid metabolism in adipose tissues.
Autorzy :
Wang Y; School of Basic Medical Sciences and Public Health, Joint China-US Research Center for Environment and Pulmonary Diseases, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Li R; School of Basic Medical Sciences and Public Health, Joint China-US Research Center for Environment and Pulmonary Diseases, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Chen R; School of Basic Medical Sciences and Public Health, Joint China-US Research Center for Environment and Pulmonary Diseases, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Gu W; School of Basic Medical Sciences and Public Health, Joint China-US Research Center for Environment and Pulmonary Diseases, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Zhang L; School of Basic Medical Sciences and Public Health, Joint China-US Research Center for Environment and Pulmonary Diseases, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Gu J; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellence in Nanoscience & Beijing Key Laboratory of Ambient Particles Health Effects and Prevention Techniques, National Center for Nanoscience and Technology of China and University of Chinese Academy of Sciences, Beijing, 100190, China.
Wang Z; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellence in Nanoscience & Beijing Key Laboratory of Ambient Particles Health Effects and Prevention Techniques, National Center for Nanoscience and Technology of China and University of Chinese Academy of Sciences, Beijing, 100190, China.
Liu Y; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellence in Nanoscience & Beijing Key Laboratory of Ambient Particles Health Effects and Prevention Techniques, National Center for Nanoscience and Technology of China and University of Chinese Academy of Sciences, Beijing, 100190, China.
Sun Q; College of Public Health, The Ohio State University, Columbus, OH, USA.
Zhang K; Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA.
Liu C; School of Basic Medical Sciences and Public Health, Joint China-US Research Center for Environment and Pulmonary Diseases, Zhejiang Chinese Medical University, Hangzhou, 310053, China. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2020 Jul; Vol. 251, pp. 126392. Date of Electronic Publication: 2020 Feb 29.
Typ publikacji :
Journal Article
MeSH Terms :
Circadian Rhythm*
Adipose Tissue/*metabolism
Inhalation Exposure/*adverse effects
Particulate Matter/*toxicity
Adipose Tissue, Brown ; Adipose Tissue, White ; Adiposity ; Animals ; Energy Metabolism/drug effects ; Homeostasis/drug effects ; Lipid Metabolism/drug effects ; Mice ; Mice, Inbred C57BL ; Obesity/chemically induced ; Particulate Matter/analysis ; Uncoupling Protein 1
Czasopismo naukowe
Tytuł :
BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning.
Autorzy :
Liu T; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.
Mi L; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
Xiong J; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
Orchard P; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, 48109, USA.
Yu Q; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
Yu L; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
Zhao XY; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
Meng ZX; Department of Pathology and Pathophysiology, Key Laboratory of Disease Proteomics of Zhejiang Province, Hangzhou, Zhejiang, 310058, China.; Chronic Disease Research Institute of School of Public Health, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310058, China.
Parker SCJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, 48109, USA.
Lin JD; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA. .
Li S; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 May 13; Vol. 11 (1), pp. 2379. Date of Electronic Publication: 2020 May 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cold Temperature*
Adipose Tissue, Brown/*metabolism
Adipose Tissue, White/*metabolism
Chromatin/*metabolism
Chromosomal Proteins, Non-Histone/*deficiency
Adipocytes, Brown/drug effects ; Adipocytes, Brown/metabolism ; Adipocytes, Brown/ultrastructure ; Adipose Tissue, Beige/metabolism ; Adipose Tissue, Brown/drug effects ; Adipose Tissue, White/drug effects ; Adrenocorticotropic Hormone/pharmacology ; Animals ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Binding Sites/genetics ; Cells, Cultured ; Chromatin/genetics ; Chromosomal Proteins, Non-Histone/genetics ; Gene Expression/drug effects ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Thermogenesis/drug effects ; Thermogenesis/genetics
Czasopismo naukowe
Tytuł :
Chronic arsenic exposure impairs adaptive thermogenesis in male C57BL/6J mice.
Autorzy :
Castriota F; Superfund Research Program, University of California, Berkeley, California.
Zushin PH; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California.
Sanchez SS; Superfund Research Program, University of California, Berkeley, California.
Phillips RV; Superfund Research Program, University of California, Berkeley, California.
Hubbard A; Superfund Research Program, University of California, Berkeley, California.
Stahl A; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California.
Smith MT; Superfund Research Program, University of California, Berkeley, California.
Wang JC; Superfund Research Program, University of California, Berkeley, California.; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California.
La Merrill MA; Department of Environmental Toxicology, University of California, Davis, California.
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Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2020 May 01; Vol. 318 (5), pp. E667-E677. Date of Electronic Publication: 2020 Feb 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Adipose Tissue, Brown/*drug effects
Arsenites/*pharmacology
Sodium Compounds/*pharmacology
Thermogenesis/*drug effects
Adipose Tissue, Brown/metabolism ; Adipose Tissue, White/drug effects ; Adipose Tissue, White/metabolism ; Animals ; Energy Metabolism/drug effects ; Male ; Membrane Transport Proteins/metabolism ; Methacrylates ; Mice ; Mice, Inbred C57BL ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Receptors, Cell Surface/metabolism ; Siloxanes ; Subcutaneous Fat/drug effects ; Subcutaneous Fat/metabolism
Czasopismo naukowe
Tytuł :
Long-term nitrate administration increases expression of browning genes in epididymal adipose tissue of male type 2 diabetic rats.
Autorzy :
Jeddi S; Endocrine Physiology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Yousefzadeh N; Endocrine Physiology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Afzali H; Endocrine Physiology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ghasemi A; Endocrine Physiology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jan 15; Vol. 766, pp. 145155. Date of Electronic Publication: 2020 Sep 17.
Typ publikacji :
Journal Article
MeSH Terms :
Adipocytes, Brown/*drug effects
Adipose Tissue, Brown/*drug effects
Adipose Tissue, White/*drug effects
Diabetes Mellitus, Experimental/*genetics
Diabetes Mellitus, Type 2/*genetics
Epididymis/*drug effects
Nitrates/*administration & dosage
Adipocytes/drug effects ; Adipocytes/metabolism ; Adipocytes, Brown/metabolism ; Adipose Tissue, Brown/metabolism ; Adipose Tissue, White/metabolism ; Animals ; Blood Glucose/metabolism ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Type 2/metabolism ; Epididymis/metabolism ; Glucose/metabolism ; Insulin/blood ; Male ; PPAR gamma/genetics ; PPAR gamma/metabolism ; RNA, Messenger/genetics ; Rats ; Rats, Wistar ; Streptozocin/pharmacology
Czasopismo naukowe
Tytuł :
Long-term exercise-secreted extracellular vesicles promote browning of white adipocytes by suppressing miR-191a-5p.
Autorzy :
Di W; Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, PR China. Electronic address: .
Amdanee N; Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, PR China. Electronic address: .
Zhang W; Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, PR China. Electronic address: .
Zhou Y; Neuroendocrine Tumor Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, PR China; Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, PR China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Dec 15; Vol. 263, pp. 118464. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Journal Article
MeSH Terms :
Physical Conditioning, Animal*
Adipose Tissue, Brown/*cytology
Adipose Tissue, White/*cytology
DNA-Binding Proteins/*metabolism
Extracellular Vesicles/*metabolism
MicroRNAs/*genetics
Obesity/*pathology
Transcription Factors/*metabolism
Adipose Tissue, Brown/metabolism ; Adipose Tissue, White/metabolism ; Animals ; DNA-Binding Proteins/genetics ; Diet, High-Fat ; Energy Metabolism ; Mice ; NIH 3T3 Cells ; Obesity/etiology ; Obesity/metabolism ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
[Time-sequential expression of lnc AK079912 during adipose tissue development and browning in mice].
Autorzy :
Huang J; Department of Physiology and Pathophysiology, Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University School of Medicine, Xi'an 710061, China.
Jia R; Department of Prosthodontics, College of Stomatology, Xi'an Jiaotong University, Xi'an 710004, China.; Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, Xi'an Jiaotong University School of Medicine, Xi'an 710061, China.
Wei X; Department of Physiology and Pathophysiology, Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University School of Medicine, Xi'an 710061, China.
Luo X; Department of Physiology and Pathophysiology, Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University School of Medicine, Xi'an 710061, China.
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Źródło :
Nan fang yi ke da xue xue bao = Journal of Southern Medical University [Nan Fang Yi Ke Da Xue Xue Bao] 2019 Dec 30; Vol. 39 (12), pp. 1494-1499.
Typ publikacji :
Journal Article
MeSH Terms :
Adipogenesis*
Adipose Tissue, Brown*
Adipocytes ; Adipose Tissue, White ; Animals ; Male ; Mice ; Mice, Inbred C57BL ; RNA, Long Noncoding
Czasopismo naukowe
Tytuł :
Is Exercise a Match for Cold Exposure? Common Molecular Framework for Adipose Tissue Browning.
Autorzy :
Martin AR; Department of Sport and Health Sciences, Technical University of Munich, Munich, Germany.; Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, United States.
Chung S; Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, United States.
Koehler K; Department of Sport and Health Sciences, Technical University of Munich, Munich, Germany.; Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, United States.
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Źródło :
International journal of sports medicine [Int J Sports Med] 2020 Jun; Vol. 41 (7), pp. 427-442. Date of Electronic Publication: 2020 Apr 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cold Temperature*
Thermogenesis*
Adipose Tissue, Brown/*metabolism
Exercise/*physiology
Adipose Tissue, Beige/metabolism ; Adipose Tissue, White/metabolism ; Animals ; Atrial Natriuretic Factor/metabolism ; Biomarkers/metabolism ; Energy Metabolism ; Fibroblast Growth Factors/metabolism ; Fibronectins/metabolism ; Humans ; Natriuretic Peptide, Brain/metabolism ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Uncoupling Protein 1/metabolism
Czasopismo naukowe
Tytuł :
Nutritional and metabolic regulation of brown and beige adipose tissues.
Autorzy :
Moreno-Aliaga MJ; Centre for Nutrition Research and Department of Nutrition, Food Sciences and Physiology, University of Navarra, Pamplona, Spain. .; Navarra's Health Research Institute (IdiSNA), Pamplona, Spain. .; CIBERobn Physiopathology of Obesity and Nutrition, Carlos III Health Institute, Madrid, Spain. .
Villarroya F; CIBERobn Physiopathology of Obesity and Nutrition, Carlos III Health Institute, Madrid, Spain. .; Department of Biochemistry and Molecular Biomedicine and Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Catalonia, Spain. .
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Źródło :
Journal of physiology and biochemistry [J Physiol Biochem] 2020 May; Vol. 76 (2), pp. 181-184. Date of Electronic Publication: 2020 May 30.
Typ publikacji :
Editorial; Introductory Journal Article
MeSH Terms :
Nutritional Physiological Phenomena*
Adipocytes, Beige/*metabolism
Adipocytes, Brown/*metabolism
Adipose Tissue, Beige/*metabolism
Adipose Tissue, Brown/*metabolism
Adipocytes, Beige/cytology ; Adipocytes, Brown/cytology ; Adipose Tissue, White/metabolism ; Animals ; Humans ; Thermogenesis
Czasopismo naukowe

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