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Wyszukujesz frazę ""Adjuvants, Immunologic"" wg kryterium: Temat


Tytuł :
Large-Sized Graphene Oxide Nanosheets Increase DC-T-Cell Synaptic Contact and the Efficacy of DC Vaccines against SARS-CoV-2.
Autorzy :
Zhou Q; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Gu H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.
Sun S; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Zhang Y; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Hou Y; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Li C; BGI college, Zhengzhou University, Henan Institute of Medical and Pharmaceutical Science, Zhengzhou University, Zhengzhou, 450001, P. R. China.
Zhao Y; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Ma P; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Lv L; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Aji S; Cold Spring Biotech Corporation, Beijing, 110000, P. R. China.
Sun S; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.
Wang X; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Zhan L; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.; BGI college, Zhengzhou University, Henan Institute of Medical and Pharmaceutical Science, Zhengzhou University, Zhengzhou, 450001, P. R. China.
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Źródło :
Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2021 Oct; Vol. 33 (40), pp. e2102528. Date of Electronic Publication: 2021 Aug 16.
Typ publikacji :
Journal Article
MeSH Terms :
Adjuvants, Immunologic/*therapeutic use
COVID-19/*prevention & control
COVID-19 Vaccines/*therapeutic use
Dendritic Cells/*immunology
Graphite/*therapeutic use
Nanostructures/*therapeutic use
Adjuvants, Immunologic/chemistry ; Animals ; COVID-19/immunology ; COVID-19 Vaccines/immunology ; Dendritic Cells/drug effects ; Graphite/chemistry ; Humans ; Mice ; Nanostructures/chemistry ; SARS-CoV-2/immunology ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
Effect of processed aloe vera gel on immunogenicity in inactivated quadrivalent influenza vaccine and upper respiratory tract infection in healthy adults: A randomized double-blind placebo-controlled trial.
Autorzy :
Hwang JH; Department of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea; Research Institute of Clinical Medicine of Jeonbuk National University, Jeonju, Jeonbuk, 54896, Republic of Korea; Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Jeonbuk, 54907, Republic of Korea.
Oh MR; Clinical Trial Center for Functional Foods, Jeonbuk National University Hospital, Jeonju, Jeonbuk 54907, Republic of Korea.
Hwang JH; Clinical Trial Center for Functional Foods, Jeonbuk National University Hospital, Jeonju, Jeonbuk 54907, Republic of Korea.
Choi EK; Clinical Trial Center for Functional Foods, Jeonbuk National University Hospital, Jeonju, Jeonbuk 54907, Republic of Korea.
Jung SJ; Clinical Trial Center for Functional Foods, Jeonbuk National University Hospital, Jeonju, Jeonbuk 54907, Republic of Korea.
Song EJ; Department of Pharmacy, Korea University College of Pharmacy, Sejong 30019, Republic of Korea.
Españo E; Department of Pharmacy, Korea University College of Pharmacy, Sejong 30019, Republic of Korea.
Webby RJ; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Webster RG; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Kim JK; Department of Pharmacy, Korea University College of Pharmacy, Sejong 30019, Republic of Korea. Electronic address: .
Chae SW; Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Jeonbuk, 54907, Republic of Korea; Clinical Trial Center for Functional Foods, Jeonbuk National University Hospital, Jeonju, Jeonbuk 54907, Republic of Korea. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Oct; Vol. 91, pp. 153668. Date of Electronic Publication: 2021 Jul 22.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Adjuvants, Immunologic*
Immunogenicity, Vaccine*
Influenza Vaccines*/immunology
Influenza, Human*/prevention & control
Plant Preparations/*chemistry
Adult ; Double-Blind Method ; Hemagglutination Inhibition Tests ; Humans ; Influenza A Virus, H3N2 Subtype/immunology
Czasopismo naukowe
Tytuł :
Clinical significance of inflammatory markers of bacterial infection in critically ill patients with COVID-19 after treatment with anti-inflammatory and immunomodulatory drugs: a complex new scenario.
Autorzy :
Giacobbe DR; Infectious Diseases Unit, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, 16132 Genoa, Italy.; Department of Health Sciences (DISSAL), University of Genoa, 16132 Genoa, Italy.
Ball L; Anesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, 16132 Genoa, Italy.; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, 16132 Genoa, Italy.
Magnasco L; Infectious Diseases Unit, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, 16132 Genoa, Italy.
Dentone C; Infectious Diseases Unit, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, 16132 Genoa, Italy.
Battaglini D; Anesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, 16132 Genoa, Italy.; Department of Medicine, University of Barcelona, 08007 Barcelona, Spain.
Robba C; Anesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, 16132 Genoa, Italy.; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, 16132 Genoa, Italy.
Pelosi P; Anesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, 16132 Genoa, Italy.; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, 16132 Genoa, Italy.
Bassetti M; Infectious Diseases Unit, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, 16132 Genoa, Italy.; Department of Health Sciences (DISSAL), University of Genoa, 16132 Genoa, Italy.
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Źródło :
Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2021 Sep 30 (9), pp. 405-408.
Typ publikacji :
Editorial
MeSH Terms :
Critical Illness*
Adjuvants, Immunologic/*therapeutic use
Anti-Inflammatory Agents/*therapeutic use
Bacterial Infections/*metabolism
COVID-19/*metabolism
Inflammation/*metabolism
Adjuvants, Immunologic/administration & dosage ; Anti-Inflammatory Agents/administration & dosage ; Biomarkers/metabolism ; COVID-19/drug therapy ; COVID-19/virology ; Humans
Opinia redakcyjna
Tytuł :
IL-7 in SARS-CoV-2 Infection and as a Potential Vaccine Adjuvant.
Autorzy :
Bekele Y; Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, United States.
Sui Y; Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, United States.
Berzofsky JA; Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Sep 17; Vol. 12, pp. 737406. Date of Electronic Publication: 2021 Sep 17 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Review
MeSH Terms :
Adjuvants, Immunologic*
COVID-19/*prevention & control
COVID-19 Vaccines/*immunology
Interleukin-7/*immunology
SARS-CoV-2/*immunology
CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; COVID-19/immunology ; Humans ; Immunogenicity, Vaccine/immunology ; Interleukin-7/metabolism ; Receptors, Interleukin-7/metabolism
Czasopismo naukowe
Tytuł :
Precision Wormlike Nanoadjuvant Governs Potency of Vaccination.
Autorzy :
Sun Z; School of Materials Science and Engineering, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-sen University, Guangzhou 510275, China.
Qiao D; School of Materials Science and Engineering, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-sen University, Guangzhou 510275, China.
Shi Y; School of Materials Science and Engineering, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-sen University, Guangzhou 510275, China.
Barz M; Leiden Academic Center for Drug Research, Division of Biotherapeutics, Laboratory for Biotherapeutic Delivery, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.; Department Chemie, Johannes Gutenberg University, Duesbergweg 10-14, 55099 Mainz, Germany.
Liu L; School of Materials Science and Engineering, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-sen University, Guangzhou 510275, China.; State Key Laboratory of Oncology in Southern China, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Chen Y; School of Materials Science and Engineering, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-sen University, Guangzhou 510275, China.; State Key Laboratory of Oncology in Southern China, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
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Źródło :
Nano letters [Nano Lett] 2021 Sep 08; Vol. 21 (17), pp. 7236-7243. Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adjuvants, Immunologic*
Vaccination*
Animals ; Disease Models, Animal ; Mice
Czasopismo naukowe
Tytuł :
Bursal peptide BP-IV as a novel immunoadjuvant enhances the protective efficacy of an epitope peptide vaccine containing T and B cell epitopes of the H9N2 avian influenza virus.
Autorzy :
Liu Y; The Key Lab of Veterinary Biological Products, Henan University of Science and Technology, Luoyang, Henan, China.
Shen T; The Key Lab of Veterinary Biological Products, Henan University of Science and Technology, Luoyang, Henan, China.
Zhou J; The Key Lab of Veterinary Biological Products, Henan University of Science and Technology, Luoyang, Henan, China.
Chen L; The Key Lab of Veterinary Biological Products, Henan University of Science and Technology, Luoyang, Henan, China.
Shi S; The Key Lab of Veterinary Biological Products, Henan University of Science and Technology, Luoyang, Henan, China.
Wang X; School of Basic Medical Sciences, Henan University of Science and Technology, Luoyang, Henan, China.
Zhang M; The Key Lab of Veterinary Biological Products, Henan University of Science and Technology, Luoyang, Henan, China.
Wang C; The Key Lab of Veterinary Biological Products, Henan University of Science and Technology, Luoyang, Henan, China. Electronic address: .
Liao C; The Key Lab of Veterinary Biological Products, Henan University of Science and Technology, Luoyang, Henan, China. Electronic address: .
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Źródło :
Microbial pathogenesis [Microb Pathog] 2021 Sep; Vol. 158, pp. 105095. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Adjuvants, Immunologic*
Influenza A Virus, H9N2 Subtype*
Influenza Vaccines*
Influenza in Birds*/prevention & control
Animals ; Antibodies, Viral ; Chickens ; Epitopes, B-Lymphocyte ; Epitopes, T-Lymphocyte ; Peptides/immunology ; Vaccines, Subunit
Czasopismo naukowe
Tytuł :
Reply to the letter to the editor: adjuvant nivolumab for the management of the pathological residual disease in esophageal or junctional tumors: a word of caution by P.K. Garg, R. Kumar and P. Dixit.
Autorzy :
Smyth EC; Cambridge University Hospitals, National Health Service Foundation Trust, Department of Oncology, Cambridge, UK.
Gambardella V; Department of Medical Oncology, Hospital Clínico Universitario de Valencia, INCLIVA Biomedical Research Institute, University of Valencia, Valencia, Spain; CIBERONC, Instituto de Salud Carlos III, Madrid, Spain.
Cervantes A; Department of Medical Oncology, Hospital Clínico Universitario de Valencia, INCLIVA Biomedical Research Institute, University of Valencia, Valencia, Spain; CIBERONC, Instituto de Salud Carlos III, Madrid, Spain. Electronic address: .
Fleitas T; Department of Medical Oncology, Hospital Clínico Universitario de Valencia, INCLIVA Biomedical Research Institute, University of Valencia, Valencia, Spain; CIBERONC, Instituto de Salud Carlos III, Madrid, Spain. Electronic address: .
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Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2021 Sep; Vol. 32 (9), pp. 1190-1191. Date of Electronic Publication: 2021 May 24.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Adjuvants, Immunologic*
Nivolumab*/adverse effects
Adjuvants, Pharmaceutic ; Humans ; Neoplasm, Residual
Raport
Tytuł :
Large-scale supercritical fluid chromatography purification of unstable STING agonist intermediates.
Autorzy :
Sun D; Department of Discovery Synthesis, Research and Early Development, Bristol Myers Squibb, Princeton, NJ 08540, United States. Electronic address: .
Wu DR; Department of Discovery Synthesis, Research and Early Development, Bristol Myers Squibb, Princeton, NJ 08540, United States.
Li P; Department of Discovery Synthesis, Research and Early Development, Bristol Myers Squibb, Princeton, NJ 08540, United States.
Yip H; Department of Discovery Synthesis, Research and Early Development, Bristol Myers Squibb, Princeton, NJ 08540, United States.
Wang B; Department of Discovery Synthesis, Research and Early Development, Bristol Myers Squibb, Princeton, NJ 08540, United States.
Hou X; Department of Discovery Synthesis, Research and Early Development, Bristol Myers Squibb, Princeton, NJ 08540, United States.
Zhao R; Department of Discovery Synthesis, Research and Early Development, Bristol Myers Squibb, Princeton, NJ 08540, United States.
Zhang H; Department of Discovery Synthesis, Research and Early Development, Bristol Myers Squibb, Princeton, NJ 08540, United States.
Kempson J; Department of Discovery Synthesis, Research and Early Development, Bristol Myers Squibb, Princeton, NJ 08540, United States.
Mathur A; Department of Discovery Synthesis, Research and Early Development, Bristol Myers Squibb, Princeton, NJ 08540, United States.
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2021 Aug 16; Vol. 1651, pp. 462309. Date of Electronic Publication: 2021 Jun 06.
Typ publikacji :
Journal Article
MeSH Terms :
Chromatography, Supercritical Fluid*
Adjuvants, Immunologic/*isolation & purification
Membrane Proteins/*agonists
Adjuvants, Immunologic/chemistry ; Ammonium Hydroxide/chemistry ; Carbon Dioxide/chemistry ; Membrane Proteins/genetics ; Methanol/chemistry ; Solvents/chemistry ; Stereoisomerism ; Temperature
Czasopismo naukowe
Tytuł :
Potent Neutralizing Antibodies Elicited by RBD-Fc-Based COVID-19 Vaccine Candidate Adjuvanted by the Th2-Skewing iNKT Cell Agonist.
Autorzy :
Wang XF; Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Zhang MJ; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei 430070, P. R. China.
He N; Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Wang YC; Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Yan C; Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Chen XZ; Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou, Jiangxi 341000, China.
Gao XF; Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China University of Technology, Nanchang, Jiangxi 330013, China.
Guo J; Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Luo R; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei 430070, P. R. China.
Liu Z; Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Aug 12; Vol. 64 (15), pp. 11554-11569. Date of Electronic Publication: 2021 Jul 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adjuvants, Immunologic*
Antibodies, Neutralizing/*immunology
COVID-19 Vaccines/*immunology
Galactosylceramides/*pharmacology
Natural Killer T-Cells/*drug effects
Animals ; Female ; HEK293 Cells ; Humans ; Mice ; Mice, Inbred BALB C ; Natural Killer T-Cells/immunology ; Th2 Cells
Czasopismo naukowe
Tytuł :
Tumor-killing nanoreactors fueled by tumor debris can enhance radiofrequency ablation therapy and boost antitumor immune responses.
Autorzy :
Yang Z; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, Jiangsu, PR China.
Zhu Y; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, Jiangsu, PR China.
Dong Z; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, Jiangsu, PR China.
Li W; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, Jiangsu, PR China.
Yang N; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, Jiangsu, PR China.
Wang X; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, Jiangsu, PR China.
Feng L; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, Jiangsu, PR China. .
Liu Z; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, Jiangsu, PR China. .; Macao Institute of Materials Science and Engineering, Macau University of Science and Technology, Taipa, Macau, PR China. .
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Źródło :
Nature communications [Nat Commun] 2021 Jul 14; Vol. 12 (1), pp. 4299. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Radiofrequency Ablation*
Adjuvants, Immunologic/*therapeutic use
Nanomedicine/*methods
Neoplasms/*therapy
Adjuvants, Immunologic/chemistry ; Adjuvants, Immunologic/pharmacology ; Animals ; Calcium Carbonate/chemistry ; Calcium Carbonate/therapeutic use ; Catalysis ; Cell Line, Tumor ; Combined Modality Therapy ; Ferroptosis/drug effects ; Hemin/chemistry ; Hemin/therapeutic use ; Humans ; Hydrogen-Ion Concentration ; Immune Checkpoint Inhibitors/therapeutic use ; Immunogenic Cell Death/drug effects ; Lipid Peroxidation/drug effects ; Lipoxygenase/chemistry ; Lipoxygenase/therapeutic use ; Mice ; Neoplasm Metastasis ; Neoplasm, Residual ; Neoplasms/immunology ; Neoplasms/pathology ; Polylactic Acid-Polyglycolic Acid Copolymer/chemistry ; Polylactic Acid-Polyglycolic Acid Copolymer/therapeutic use ; Rabbits
Czasopismo naukowe
Tytuł :
Absorption, distribution, metabolism and excretion of hyaluronic acid during pregnancy: a matter of molecular weight.
Autorzy :
Unfer V; Systems Biology Group Lab, Rome, Italy.
Tilotta M; R&D Department,Lo.Li. Pharma S.r.l., Rome, Italy.
Kaya C; Department of Obstetrics and Gynaecology, University of Health Sciences, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Noventa M; Department of Women and Children's Health, Clinic of Gynecology and Obstetrics, University of Padua, Padua, Italy.
Török P; Faculty of Medicine, Institute of Obstetrics and Gynecology, University of Debrecen, Hungary.
Alkatout I; Department of Obstetrics and Gynecology, University Hospital Schleswig Holstein, Kiel, Germany.
Gitas G; Department of Obstetrics and Gynecology, University Hospital Schleswig Holstein, Lübeck, Germany.
Bilotta G; Alma Res Fertility Center, Rome, Italy.
Laganà AS; Department of Obstetrics and Gynecology, 'Filippo Del Ponte' Hospital,University of Insubria, Varese, Italy.
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Źródło :
Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2021 Jul; Vol. 17 (7), pp. 823-840. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adjuvants, Immunologic/*administration & dosage
Hyaluronic Acid/*administration & dosage
Abortion, Spontaneous/prevention & control ; Adjuvants, Immunologic/chemistry ; Adjuvants, Immunologic/pharmacokinetics ; Animals ; Female ; Humans ; Hyaluronic Acid/chemistry ; Hyaluronic Acid/pharmacokinetics ; Molecular Weight ; Pregnancy ; Premature Birth/prevention & control
Czasopismo naukowe
Tytuł :
Purification, structural characterization and immunostimulatory activity of polysaccharides from Umbilicaria esculenta.
Autorzy :
Shi Y; Engineering Research Center of Bio-process, Ministry of Education, Hefei University of Technology, Hefei 230009, People's Republic of China; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, People's Republic of China.
Ye YF; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, People's Republic of China.
Zhang BW; The Key Laboratory for Agricultural Products Processing of Anhui Province, Hefei University of Technology, Hefei 230009, People's Republic of China.
Liu Y; Engineering Research Center of Bio-process, Ministry of Education, Hefei University of Technology, Hefei 230009, People's Republic of China; The Key Laboratory for Agricultural Products Processing of Anhui Province, Hefei University of Technology, Hefei 230009, People's Republic of China. Electronic address: .
Wang JH; Engineering Research Center of Bio-process, Ministry of Education, Hefei University of Technology, Hefei 230009, People's Republic of China; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, People's Republic of China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jun 30; Vol. 181, pp. 743-751. Date of Electronic Publication: 2021 Mar 30.
Typ publikacji :
Journal Article
MeSH Terms :
Adjuvants, Immunologic/*pharmacology
Ascomycota/*chemistry
Polysaccharides/*chemistry
Polysaccharides/*pharmacology
Adjuvants, Immunologic/chemistry ; Adjuvants, Immunologic/isolation & purification ; Animals ; Carbon-13 Magnetic Resonance Spectroscopy ; Cell Survival/drug effects ; Gas Chromatography-Mass Spectrometry ; Glycosides/chemistry ; Mice ; Monosaccharides/analysis ; Polysaccharides/isolation & purification ; Proton Magnetic Resonance Spectroscopy ; RAW 264.7 Cells ; Spectroscopy, Fourier Transform Infrared
SCR Organism :
Umbilicaria esculenta
Czasopismo naukowe
Tytuł :
Structural Fine-Tuning of Desmuramylpeptide NOD2 Agonists Defines Their In Vivo Adjuvant Activity.
Autorzy :
Guzelj S; Faculty of Pharmacy, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Nabergoj S; Faculty of Pharmacy, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Gobec M; Faculty of Pharmacy, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Pajk S; Faculty of Pharmacy, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Klančič V; Faculty of Pharmacy, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Slütter B; Div. BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.
Frkanec R; Centre for Research and Knowledge Transfer in Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.
Štimac A; Centre for Research and Knowledge Transfer in Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.
Šket P; Slovenian NMR Centre, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.
Plavec J; Slovenian NMR Centre, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.
Mlinarič-Raščan I; Faculty of Pharmacy, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Jakopin Ž; Faculty of Pharmacy, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Jun 10; Vol. 64 (11), pp. 7809-7838. Date of Electronic Publication: 2021 May 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylmuramyl-Alanyl-Isoglutamine/*chemistry
Adjuvants, Immunologic/*chemistry
Nod2 Signaling Adaptor Protein/*agonists
Acetylmuramyl-Alanyl-Isoglutamine/metabolism ; Acetylmuramyl-Alanyl-Isoglutamine/pharmacology ; Adjuvants, Immunologic/metabolism ; Adjuvants, Immunologic/pharmacology ; Animals ; Antibody Formation/drug effects ; Cell Line ; Drug Design ; Humans ; Immunoglobulin G/metabolism ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Leukocytes, Mononuclear/cytology ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/metabolism ; Liposomes/chemistry ; Lymphocyte Activation/drug effects ; Mice ; Mice, Inbred C57BL ; Nod2 Signaling Adaptor Protein/metabolism ; Ovalbumin/immunology ; Structure-Activity Relationship ; Th1 Cells/cytology ; Th1 Cells/immunology ; Th1 Cells/metabolism ; Th2 Cells/cytology ; Th2 Cells/immunology ; Th2 Cells/metabolism
Czasopismo naukowe
Tytuł :
Antitumor effect of soluble β-glucan as an immune stimulant.
Autorzy :
Wu L; School of Medicine and Pharmacy, Ocean University of China, 23 East Hongkang Road, Qingdao, Shandong 266071, China; Innovation Platform of Marine Drug Screening & Evaluation, Qingdao National Laboratory for Marine Science and Technology, Qingdao, Shandong 266100, China.
Zhao J; Innovation Platform of Marine Drug Screening & Evaluation, Qingdao National Laboratory for Marine Science and Technology, Qingdao, Shandong 266100, China.
Zhang X; Innovation Platform of Marine Drug Screening & Evaluation, Qingdao National Laboratory for Marine Science and Technology, Qingdao, Shandong 266100, China.
Liu S; Innovation Platform of Marine Drug Screening & Evaluation, Qingdao National Laboratory for Marine Science and Technology, Qingdao, Shandong 266100, China.
Zhao C; School of Medicine and Pharmacy, Ocean University of China, 23 East Hongkang Road, Qingdao, Shandong 266071, China; Innovation Platform of Marine Drug Screening & Evaluation, Qingdao National Laboratory for Marine Science and Technology, Qingdao, Shandong 266100, China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 May 15; Vol. 179, pp. 116-124. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adjuvants, Immunologic*/chemistry
Adjuvants, Immunologic*/therapeutic use
Neoplasms*/immunology
Neoplasms*/pathology
Neoplasms*/therapy
beta-Glucans*/chemistry
beta-Glucans*/immunology
beta-Glucans*/therapeutic use
Animals ; Humans
Czasopismo naukowe
Tytuł :
Portulaca oleracea L. polysaccharides enhance the immune efficacy of dendritic cell vaccine for breast cancer.
Autorzy :
Jia G; Department of Pharmaceutical Engineering, College of Life Science & Biotechnology, Heilongjiang August First Land Reclamation University, Daqing High-Tech Industrial Development Zone, 163319, P. R. China. .
Shao X; Department of gynaecology and obstetrics, Daqing Oilfield Hospital, Daqing 163311, P. R China.
Zhao R; Department of Pharmaceutical Engineering, College of Life Science & Biotechnology, Heilongjiang August First Land Reclamation University, Daqing High-Tech Industrial Development Zone, 163319, P. R. China. .
Zhang T; School of Basic Medical Sciences, Jiamusi University, No. 188 Xuefu Street, Jiamusi City, Heilongjiang Province 154007, P. R. China.
Zhou X; Institute of Animal Science and Technology, Heilongjiang August First Land Reclamation University, Daqing High-Tech Industrial Development Zone, 163319, P. R. China.
Yang Y; Department of Pharmaceutical Engineering, College of Life Science & Biotechnology, Heilongjiang August First Land Reclamation University, Daqing High-Tech Industrial Development Zone, 163319, P. R. China. .
Li T; Department of Pharmaceutical Engineering, College of Life Science & Biotechnology, Heilongjiang August First Land Reclamation University, Daqing High-Tech Industrial Development Zone, 163319, P. R. China. .
Chen Z; Department of Pharmaceutical Engineering, College of Life Science & Biotechnology, Heilongjiang August First Land Reclamation University, Daqing High-Tech Industrial Development Zone, 163319, P. R. China. .
Liu Y; Department of Pharmaceutical Engineering, College of Life Science & Biotechnology, Heilongjiang August First Land Reclamation University, Daqing High-Tech Industrial Development Zone, 163319, P. R. China. .
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Źródło :
Food & function [Food Funct] 2021 May 11; Vol. 12 (9), pp. 4046-4059.
Typ publikacji :
Journal Article
MeSH Terms :
Adjuvants, Immunologic*/administration & dosage
Adjuvants, Immunologic*/toxicity
Breast Neoplasms/*therapy
Cancer Vaccines/*immunology
Cancer Vaccines/*therapeutic use
Dendritic Cells/*immunology
Polysaccharides/*immunology
Portulaca/*chemistry
Animals ; Antigens, Neoplasm/immunology ; Apoptosis ; Breast Neoplasms/immunology ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Female ; Immunogenicity, Vaccine ; Mammary Neoplasms, Experimental/immunology ; Mammary Neoplasms, Experimental/pathology ; Mammary Neoplasms, Experimental/therapy ; Mice ; Mice, Inbred BALB C ; Neoplasm Metastasis ; Polysaccharides/toxicity
Czasopismo naukowe
Tytuł :
Preparation of polyacrylate/nanoemulsion composites and their adjuvant activity with OVA as the model antigen.
Autorzy :
Zhou M; School of Materials Science and Engineering, Hebei University of Technology, 300130, Tianjin, PR China; Institute of Energy Resources, Hebei Academy of Sciences, 050081, Shijiazhuang, Hebei Province, PR China.
Bi Y; School of Materials Science and Engineering, Hebei University of Science and Technology, Hebei Engineering Laboratory of Aviation Lightweight Composite Materials and Processing Technology, Hebei Key Laboratory of Materials Near-Net Forming Technology, Hebei Key Laboratory of Flexible Functional Materials, 050018, Shijiazhuang, Hebei Province, PR China.
Li C; School of Materials Science and Engineering, Hebei University of Science and Technology, Hebei Engineering Laboratory of Aviation Lightweight Composite Materials and Processing Technology, Hebei Key Laboratory of Materials Near-Net Forming Technology, Hebei Key Laboratory of Flexible Functional Materials, 050018, Shijiazhuang, Hebei Province, PR China.
Chen X; Institute of Energy Resources, Hebei Academy of Sciences, 050081, Shijiazhuang, Hebei Province, PR China.
Zhang F; Institute of Energy Resources, Hebei Academy of Sciences, 050081, Shijiazhuang, Hebei Province, PR China.
Zhou H; Institute of Energy Resources, Hebei Academy of Sciences, 050081, Shijiazhuang, Hebei Province, PR China.
Xiao J; School of Materials Science and Engineering, Hebei University of Science and Technology, Hebei Engineering Laboratory of Aviation Lightweight Composite Materials and Processing Technology, Hebei Key Laboratory of Materials Near-Net Forming Technology, Hebei Key Laboratory of Flexible Functional Materials, 050018, Shijiazhuang, Hebei Province, PR China.
Li Y; Institute of Energy Resources, Hebei Academy of Sciences, 050081, Shijiazhuang, Hebei Province, PR China. Electronic address: .
Qu X; School of Materials Science and Engineering, Hebei University of Technology, 300130, Tianjin, PR China. Electronic address: .
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Źródło :
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2021 Nov; Vol. 207, pp. 112015. Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Adjuvants, Immunologic*/pharmacology
Antigens*
Animals ; Immunity, Cellular ; Mice ; Ovalbumin ; Particle Size
Czasopismo naukowe
Tytuł :
Development, Validation, and Application of the LC-MS/MS Method for Determination of 4-Acetamidobenzoic Acid in Pharmacokinetic Pilot Studies in Pigs.
Autorzy :
Markowska P; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-718 Olsztyn, Poland.
Procajło Z; Department of Epizootiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-718 Olsztyn, Poland.
Wolska J; Department of Anaesthesiology and Intensive Care, Faculty of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Al. Warszawska 30, 11-082 Olsztyn, Poland.
Jaroszewski JJ; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-718 Olsztyn, Poland.
Ziółkowski H; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-718 Olsztyn, Poland.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 23; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 23.
Typ publikacji :
Journal Article
MeSH Terms :
Adjuvants, Immunologic/*pharmacokinetics
Antiviral Agents/*pharmacokinetics
Chromatography, High Pressure Liquid/*methods
Inosine Pranobex/*pharmacokinetics
Tandem Mass Spectrometry/*methods
para-Aminobenzoates/*pharmacokinetics
Adjuvants, Immunologic/administration & dosage ; Animals ; Antiviral Agents/administration & dosage ; Inosine Pranobex/administration & dosage ; Pilot Projects ; Swine
Czasopismo naukowe
Tytuł :
Immunostimulatory effect of chitosan and quaternary chitosan: A review of potential vaccine adjuvants.
Autorzy :
Li X; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), No. 1 Wenhai Road, Qingdao, 266237, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Xing R; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), No. 1 Wenhai Road, Qingdao, 266237, China; University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: .
Xu C; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), No. 1 Wenhai Road, Qingdao, 266237, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Liu S; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), No. 1 Wenhai Road, Qingdao, 266237, China.
Qin Y; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), No. 1 Wenhai Road, Qingdao, 266237, China.
Li K; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), No. 1 Wenhai Road, Qingdao, 266237, China.
Yu H; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), No. 1 Wenhai Road, Qingdao, 266237, China.
Li P; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), No. 1 Wenhai Road, Qingdao, 266237, China.
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2021 Jul 15; Vol. 264, pp. 118050. Date of Electronic Publication: 2021 Apr 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adjuvants, Immunologic/*pharmacology
Chitosan/*pharmacology
Immunity/*drug effects
Vaccines/*immunology
Adjuvants, Immunologic/chemistry ; Administration, Intranasal ; Animals ; Chitosan/chemistry ; Chitosan/immunology ; Humans ; Immunization/methods ; Mice ; Nanoparticles/administration & dosage ; Nanoparticles/chemistry ; Vaccines/chemistry
Czasopismo naukowe
Tytuł :
A purified acidic polysaccharide from Sarcandra glabra as vaccine adjuvant to enhance anti-tumor effect of cancer vaccine.
Autorzy :
Liu W; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals and State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, Nanjing, 210009, China.
Gong X; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals and State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, Nanjing, 210009, China.
Luo J; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals and State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, Nanjing, 210009, China.
Jiang L; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals and State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, Nanjing, 210009, China.
Lu W; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals and State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, Nanjing, 210009, China.
Pan C; Department of Critical Care Medicine, Zhongda Hospital, Southeast University, Nanjing, 210009, China.
Yao W; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals and State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, Nanjing, 210009, China.
Gao X; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals and State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, Nanjing, 210009, China. Electronic address: .
Tian H; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals and State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, Nanjing, 210009, China. Electronic address: .
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2021 Jul 01; Vol. 263, pp. 117967. Date of Electronic Publication: 2021 Mar 19.
Typ publikacji :
Journal Article
MeSH Terms :
Adjuvants, Immunologic/*pharmacology
Cancer Vaccines/*pharmacology
Magnoliopsida/*chemistry
Neoplasms/*drug therapy
Polysaccharides/*immunology
Acids/chemistry ; Adaptor Proteins, Signal Transducing/genetics ; Adjuvants, Immunologic/administration & dosage ; Animals ; Calcium-Binding Proteins/genetics ; Cancer Vaccines/administration & dosage ; Cell Line, Tumor ; Dendritic Cells/immunology ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Immunity, Cellular/drug effects ; Immunity, Humoral/drug effects ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Neoplasms/pathology ; Polysaccharides/administration & dosage ; Polysaccharides/chemistry ; Th1 Cells/immunology ; Toll-Like Receptor 4/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
Cross-protective potential of a MF59-adjuvanted quadrivalent influenza vaccine in older adults.
Autorzy :
Isakova-Sivak I; Institute of Experimental Medicine, Saint Petersburg 197376, Russia. Electronic address: .
Rudenko L; Institute of Experimental Medicine, Saint Petersburg 197376, Russia.
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Źródło :
The Lancet. Infectious diseases [Lancet Infect Dis] 2021 Jul; Vol. 21 (7), pp. 900-901. Date of Electronic Publication: 2021 Feb 09.
Typ publikacji :
Journal Article
MeSH Terms :
Adjuvants, Immunologic*
Cross Protection*
Aging/*immunology
Influenza A Virus, H3N2 Subtype/*immunology
Influenza Vaccines/*immunology
Influenza, Human/*immunology
Influenza, Human/*prevention & control
Aged ; Humans ; Polysorbates ; Squalene/immunology
Czasopismo naukowe

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