Temat: "Administration, Oral" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Biochemical and histopathological analysis after sub-chronic administration of oxyresveratrol in Wistar rats.
Autorzy:: Alam N; Department of Biochemistry, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, India.
Najnin H; Department of Biochemistry, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, India.
Islam M; Department of Chemistry, Faculty of Science, Aligarh Muslim University, Aligarh, India.
Shakya S; Department of Chemistry, Faculty of Science, Aligarh Muslim University, Aligarh, India.
Khan IM; Department of Chemistry, Faculty of Science, Aligarh Muslim University, Aligarh, India.
Zaidi R; Department of Biochemistry, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, India.; Pokaż więcej
Źródło:: Drug and chemical toxicology [Drug Chem Toxicol] 2023 Jan; Vol. 46 (1), pp. 166-175. Date of Electronic Publication: 2021 Dec 16.
Typ publikacji:: Journal Article
MeSH Terms:: Plant Extracts*/toxicity
Stilbenes*/toxicity
Rats ; Female ; Male ; Animals ; Rats, Wistar ; Toxicity Tests, Acute ; Administration, Oral

Czasopismo naukowe

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Skocz do pozycji: 2.

Tytuł:: Acute and Subacute Toxicity Studies of Erodium guttatum Extracts by Oral Administration in Rodents.
Autorzy:: Benrahou K; Laboratory of Pharmacology and Toxicology, Bio Pharmaceutical and Toxicological Analyzes Research Team, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat 10100, Morocco.
Mrabti HN; Laboratory of Pharmacology and Toxicology, Bio Pharmaceutical and Toxicological Analyzes Research Team, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat 10100, Morocco.
Assaggaf HM; Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Mortada S; Laboratory of Pharmacology and Toxicology, Bio Pharmaceutical and Toxicological Analyzes Research Team, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat 10100, Morocco.
Salhi N; Laboratory of Pharmacology and Toxicology, Bio Pharmaceutical and Toxicological Analyzes Research Team, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat 10100, Morocco.
Rouas L; UPR of Pathological Anatomy and Cytology, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat 10100, Morocco.
El Bacha R; Military Instruction Hospital Mohammed V, Rabat 10045, Morocco.
Dami A; Military Instruction Hospital Mohammed V, Rabat 10045, Morocco.
Masrar A; Central Laboratory of Hematology, Ibn Sina Hospital, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat 10045, Morocco.
Alshahrani MM; Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Najran University, Najran 61441, Saudi Arabia.
Awadh AAA; Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Najran University, Najran 61441, Saudi Arabia.
Bouyahya A; Laboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, and Genomic Center of Human Pathologies, Mohammed V University in Rabat, Rabat 10106, Morocco.
Goh KW; Faculty of Data Science and Information Technology, INTI International University, Nilai 71800, Malaysia.
Ming LC; Pengiran Anak Puteri Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong BE1410, Brunéi.
Cherrah Y; Laboratory of Pharmacology and Toxicology, Bio Pharmaceutical and Toxicological Analyzes Research Team, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat 10100, Morocco.
Faouzi MEA; Laboratory of Pharmacology and Toxicology, Bio Pharmaceutical and Toxicological Analyzes Research Team, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat 10100, Morocco.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2022 Oct 27; Vol. 14 (11). Date of Electronic Publication: 2022 Oct 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Rodentia*
Plant Extracts*/toxicity
Animals ; Mice ; Toxicity Tests, Acute ; Lethal Dose 50 ; Administration, Oral

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Skocz do pozycji: 3.

Tytuł:: Safety Evaluation of Oleoresin-Based Turmeric Formulation: Assessment of Genotoxicity and Acute and Subchronic Oral Toxicity.
Autorzy:: Nirvanashetty S; - Olene Life Sciences Private Limited, Chennai, 600058 Tamil Nadu, India.
Panda SK; - Olene Life Sciences Private Limited, Chennai, 600058 Tamil Nadu, India.
Jackson-Michel S; Dolcas Biotech, LLC 9 Lenel Road, Landing NJ 07850, USA.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2022 Mar 31; Vol. 2022, pp. 5281660. Date of Electronic Publication: 2022 Mar 31 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Curcuma*
Plant Extracts*/toxicity
Administration, Oral ; Animals ; Body Weight ; DNA Damage ; Mutagenicity Tests ; Mutagens ; Rats ; Rats, Sprague-Dawley ; Toxicity Tests, Acute ; Toxicity Tests, Subchronic

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Skocz do pozycji: 4.

Tytuł:: Increase water solubility of Centella asiatica extract by indigenous bioenhancers could improve oral bioavailability and disposition kinetics of triterpenoid glycosides in beagle dogs.
Autorzy:: Boonyarattanasoonthorn T; Department of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Kijtawornrat A; Department of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Songvut P; Laboratory of Pharmacology, Chulabhorn Research Institute, Bangkok, Thailand.
Nuengchamnong N; Science Laboratory Center, Faculty of Science, Naresuan University, Phitsanulok, Thailand.
Buranasudja V; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, 254 Phayathai road, Pathumwan, Bangkok, 10330, Thailand. .
Khemawoot P; Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samutprakarn, 10540, Thailand. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Feb 21; Vol. 12 (1), pp. 2909. Date of Electronic Publication: 2022 Feb 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Water*
Glycosides/*pharmacokinetics
Plant Extracts/*administration & dosage
Plant Extracts/*pharmacokinetics
Triterpenes/*pharmacokinetics
Administration, Oral ; Animals ; Biological Availability ; Centella/chemistry ; Dogs ; Glycosides/analysis ; Pentacyclic Triterpenes/analysis ; Pentacyclic Triterpenes/pharmacokinetics ; Plant Extracts/chemistry ; Solubility ; Triterpenes/administration & dosage ; Triterpenes/analysis ; Triterpenes/chemistry

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Skocz do pozycji: 5.

Tytuł:: Nanostructured Lipid Carriers Can Enhance Oral Absorption of Khellin, a Natural Pleiotropic Molecule.
Autorzy:: Vanti G; Department of Chemistry, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
Muti L; Department of Chemistry, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
D'Ambrosio M; Department of Neurofarba, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.
Grifoni L; Department of Chemistry, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
Bergonzi MC; Department of Chemistry, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
Luceri C; Department of Neurofarba, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.
Bilia AR; Department of Chemistry, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Dec 17; Vol. 26 (24). Date of Electronic Publication: 2021 Dec 17.
Typ publikacji:: Journal Article
MeSH Terms:: Cannabis*/chemistry
Khellin*/chemistry
Khellin*/pharmacokinetics
Khellin*/pharmacology
Plant Extracts*/chemistry
Plant Extracts*/pharmacokinetics
Plant Extracts*/pharmacology
Nanostructures/*chemistry
Administration, Oral ; Caco-2 Cells ; Humans ; Stearic Acids/chemistry ; Stearic Acids/pharmacokinetics ; Stearic Acids/pharmacology

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Skocz do pozycji: 6.

Tytuł:: Anti-inflammatory, expectorant, and antitussive properties of Kyeongok-go in ICR mice.
Autorzy:: Hu JR; Department of Histology and Anatomy, College of Korean Medicine, Daegu Haany University, Gyeongsan-si, Republic of Korea.
Jung CJ; Okchundang Inc, Ulsan, Republic of Korea.
Ku SM; Okchundang Inc, Ulsan, Republic of Korea.
Jung DH; Department of Pharmaceutical Engineering, Daegu Haany University, Gyeongsan, Republic of Korea.
Bashir KMI; German Engineering Research Center for Life Science Technologies in Medicine and Environment, Busan, Republic of Korea.
Ku SK; Department of Histology and Anatomy, College of Korean Medicine, Daegu Haany University, Gyeongsan-si, Republic of Korea.; The Medical Research Center for Herbal Convergence on Liver Disease, Daegu Haany University, Gyeongsan-si, Republic of Korea.
Choi JS; Department of in Food Biotechnology, College of Medical and Life Sciences, Silla University, Busan, Republic of Korea.; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2021 Dec; Vol. 59 (1), pp. 321-334.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Antitussive Agents/*pharmacology
Expectorants/*pharmacology
Plant Extracts/*pharmacology
Administration, Oral ; Animals ; Anti-Inflammatory Agents/administration & dosage ; Antitussive Agents/administration & dosage ; Cough/drug therapy ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Expectorants/administration & dosage ; Inflammation/drug therapy ; Male ; Mice ; Mice, Inbred ICR ; Phytotherapy/methods ; Plant Extracts/administration & dosage

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Skocz do pozycji: 7.

Tytuł:: Hepatoprotective effect and metabonomics studies of radix gentianae in rats with acute liver injury.
Autorzy:: Xu S; Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China.
Kong F; Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China.
Sun Z; Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China.
Xi Y; Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China.
Qi F; Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China.
Sun J; Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China.; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2021 Dec; Vol. 59 (1), pp. 1172-1180.
Typ publikacji:: Journal Article
MeSH Terms:: Metabolomics*
Liver Diseases/*prevention & control
Plant Extracts/*pharmacology
Administration, Oral ; Animals ; Biomarkers/metabolism ; Carbon Tetrachloride ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Gentiana ; Liver Diseases/metabolism ; Male ; Plant Extracts/administration & dosage ; Protective Agents/administration & dosage ; Protective Agents/pharmacology ; Rats ; Rats, Sprague-Dawley

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Skocz do pozycji: 8.

Tytuł:: A Pharmacokinetic Study of Ephedrine and Pseudoephedrine after Oral Administration of Ojeok-San by Validated LC-MS/MS Method in Human Plasma.
Autorzy:: Lee S; Department of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Shim WS; Kyung Hee Drug Analysis Center, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.
Yoo H; Kyung Hee Drug Analysis Center, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.
Choi S; Department of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea.; Kyung Hee Drug Analysis Center, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.
Yoon J; Department of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea.; Kyung Hee Drug Analysis Center, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.
Lee KY; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.
Chung EK; Department of Fundamental Pharmaceutical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Lee BC; Department of Clinical Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Yim SV; Department of Clinical Pharmacology and Therapeutics, Kyung Hee University Medical Center, Seoul 02447, Korea.; Department of Biomedical Science and Technology, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Kim BH; Department of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea.; Department of Clinical Pharmacology and Therapeutics, Kyung Hee University Medical Center, Seoul 02447, Korea.; Department of Biomedical Science and Technology, Graduate School, Kyung Hee University, Seoul 02447, Korea.; East-West Medical Research Institute, Kyung Hee University, Seoul 02447, Korea.
Lee KT; Department of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea.; Kyung Hee Drug Analysis Center, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Nov 19; Vol. 26 (22). Date of Electronic Publication: 2021 Nov 19.
Typ publikacji:: Journal Article; Validation Study
MeSH Terms:: Ephedrine*/administration & dosage
Ephedrine*/pharmacokinetics
Pseudoephedrine*/administration & dosage
Pseudoephedrine*/pharmacokinetics
Tandem Mass Spectrometry*
Plant Extracts/*administration & dosage
Administration, Oral ; Chromatography, Liquid ; Female ; Humans ; Male ; Republic of Korea

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Skocz do pozycji: 9.

Tytuł:: Antimicrobial and cytotoxic capacity of pyroligneous extracts films of Eucalyptus grandis and chitosan for oral applications.
Autorzy:: de Souza JLS; Post-Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas, Eliseu Maciel Avenue, Building 31, Pelotas, RS, 96010-900, Brazil.
Alves T; Graduate Program in Oral and Craniofacial Biomedicine, University of North Carolina at Chapel Hill, 385 S Columbia St, Chapel Hill, NC, 27599, USA.
Camerini L; Post-Graduate Program in Health and Behavior, Catholic University of Pelotas, 373 Gonçalves Chaves Street, Room 411C, Pelotas, RS, 96015-560, Brazil.
Nedel F; Post-Graduate Program in Health and Behavior, Catholic University of Pelotas, 373 Gonçalves Chaves Street, Room 411C, Pelotas, RS, 96015-560, Brazil.
Campos AD; Brazilian Agricultural Research Corporation, Embrapa Temperate Climate, Highway BR-392, 78th km, 9th district, Monte Bonito, Pelotas, RS, 96010-971, Brazil.
Lund RG; Post-Graduate Program in Biochemistry and Bioprospecting, Laboratory of Oral Microbiology, Pelotas Dental School, Federal University of Pelotas, 457 Gonçalves Chaves, Room 503, Pelotas, RS, 96015-560, Brazil. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Nov 02; Vol. 11 (1), pp. 21531. Date of Electronic Publication: 2021 Nov 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anti-Bacterial Agents/*pharmacology
Bacteria/*drug effects
Chitosan/*chemistry
Eucalyptus/*chemistry
Plant Extracts/*pharmacology
Terpenes/*chemistry
Tooth Demineralization/*prevention & control
Administration, Oral ; Adult ; Animals ; Bacteria/classification ; Bacteria/growth & development ; Biofilms/drug effects ; Biofilms/growth & development ; Cariostatic Agents/administration & dosage ; Cariostatic Agents/pharmacology ; Cell Proliferation ; Female ; Humans ; Mice ; NIH 3T3 Cells ; Plant Extracts/administration & dosage ; Polymers/chemistry ; Young Adult

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Skocz do pozycji: 10.

Tytuł:: Exploring the potential of solid dispersion for improving solubility, dissolution & bioavailability of herbal extracts, enriched fractions, and bioactives.
Autorzy:: Mohapatra D; Phytomedicine Research Lab., Department of Pharmaceutical Engineering & Technology, IIT (BHU), Varanasi, India.
Agrawal AK; Phytomedicine Research Lab., Department of Pharmaceutical Engineering & Technology, IIT (BHU), Varanasi, India.
Sahu AN; Phytomedicine Research Lab., Department of Pharmaceutical Engineering & Technology, IIT (BHU), Varanasi, India.; Pokaż więcej
Źródło:: Journal of microencapsulation [J Microencapsul] 2021 Nov-Dec; Vol. 38 (7-8), pp. 594-612. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Excipients*
Plant Extracts*
Administration, Oral ; Biological Availability ; Solubility

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Skocz do pozycji: 11.

Tytuł:: Toxicological evaluation of a flavonoid, chrysin: morphological, behavioral, biochemical and histopathological assessments in rats.
Autorzy:: Yao W; Emergency Department, The First Hospital of Lanzhou University, Lanzhou, China.
Cheng J; Department of Pathology and Central Laboratory, Heze Medical College, Heze, China.
Kandhare AD; Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Pune, India.
Mukherjee-Kandhare AA; Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Pune, India.
Bodhankar SL; Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Pune, India.
Lu G; Department of Trauma-Emergency & Critical Care Medicine, Shanghai Fifth People's Hospital Affiliated to Fudan University, Shanghai, China.; Pokaż więcej
Źródło:: Drug and chemical toxicology [Drug Chem Toxicol] 2021 Nov; Vol. 44 (6), pp. 601-612. Date of Electronic Publication: 2019 Nov 14.
Typ publikacji:: Journal Article
MeSH Terms:: Flavonoids*/toxicity
Plant Extracts*
Administration, Oral ; Animals ; Lethal Dose 50 ; Male ; Rats ; Rats, Sprague-Dawley ; Toxicity Tests, Acute

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Skocz do pozycji: 12.

Tytuł:: Pentahydroxy flavonoid isolated from Madhuca indica ameliorated adjuvant-induced arthritis via modulation of inflammatory pathways.
Autorzy:: Tang Y; Department of Orthopaedics, Xi'an Jiaotong University, Xi'an, 710000, China.; Department of Orthopaedics, Xi'an Central Hospital, Xi'an, 710000, China.
Xie D; Department of Technology, Shaanxi Nuoxing Youchuang Medical Research Center, Xi'an, 710032, China.
Gong W; Department of Ultrasound, Xijing Hospital, the Fourth Military Medical University, Xi'an, 710032, China.
Wu H; Department of Gynecology, Xianyang Central Hospital, Xianyang, 712000, China.
Qiang Y; Department of Orthopaedics, The Affiliated Hospital of Northwest University, Xi'an No. 3 Hospital, Xi'an, 710018, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Sep 09; Vol. 11 (1), pp. 17971. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji:: Journal Article
MeSH Terms:: Antirheumatic Agents/*administration & dosage
Arthritis, Experimental/*drug therapy
Arthritis, Rheumatoid/*drug therapy
Flavonoids/*administration & dosage
Madhuca/*chemistry
Phytotherapy/*methods
Plant Extracts/*administration & dosage
Plants, Medicinal/*chemistry
Adjuvants, Immunologic/adverse effects ; Administration, Oral ; Animals ; Antirheumatic Agents/chemistry ; Antirheumatic Agents/isolation & purification ; Arthritis, Experimental/chemically induced ; Arthritis, Experimental/metabolism ; Arthritis, Rheumatoid/chemically induced ; Arthritis, Rheumatoid/metabolism ; Cyclooxygenase 2/metabolism ; Cytokines/metabolism ; Female ; Flavonoids/chemistry ; Flavonoids/isolation & purification ; Freund's Adjuvant/adverse effects ; Hyperalgesia/chemically induced ; Hyperalgesia/drug therapy ; Hyperalgesia/metabolism ; Molecular Structure ; NF-kappa B/metabolism ; Nitrosative Stress/drug effects ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Rats ; Rats, Wistar ; Signal Transduction/drug effects ; Treatment Outcome

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Skocz do pozycji: 13.

Tytuł:: Acute and 28-day oral toxicity studies of methanolic extract of Lagenaria siceraria ( Cucurbitaceae ) fruit in rats.
Autorzy:: Shendge PN; Department of Pharmacology, School of Pharmacy & Technology Management, SVKM's NMIMS, Shirpur, India.
Belemkar S; Department of Pharmacology, School of Pharmacy & Technology Management, SVKM's NMIMS, Shirpur, India.; Pokaż więcej
Źródło:: Drug and chemical toxicology [Drug Chem Toxicol] 2021 Sep; Vol. 44 (5), pp. 493-501. Date of Electronic Publication: 2019 May 31.
Typ publikacji:: Journal Article
MeSH Terms:: Cucurbitaceae/*chemistry
Plant Extracts/*toxicity
Administration, Oral ; Animals ; Dose-Response Relationship, Drug ; Female ; Fruit ; Lethal Dose 50 ; Male ; Methanol/chemistry ; Plant Extracts/administration & dosage ; Rats ; Rats, Wistar ; Toxicity Tests, Acute ; Toxicity Tests, Subacute

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Skocz do pozycji: 14.

Tytuł:: Rapidly identifying bioactive compounds from Zhisou oral liquid by immobilized receptor-based high-performance affinity chromatography.
Autorzy:: Fu X; College of Life Sciences, Northwest University, Xi'an, P. R. China.
Zhao X; College of Life Sciences, Northwest University, Xi'an, P. R. China.
Zheng X; College of Life Sciences, Northwest University, Xi'an, P. R. China.
Wang T; College of Life Sciences, Northwest University, Xi'an, P. R. China.
Shayiranbieke A; College of Life Sciences, Northwest University, Xi'an, P. R. China.
Li L; College of Life Sciences, Northwest University, Xi'an, P. R. China.
Cao F; Shaanxi Pharmaceutical Holding Group Shanhaidan Pharmaceutical Co., Ltd., Xi'an, P. R. China.
Ren J; Medicine Research Institution of Shaanxi Pharmaceutical Holding Cooperation, Xi'an, P. R. China.
Li Q; College of Life Sciences, Northwest University, Xi'an, P. R. China.
Zhao X; College of Life Sciences, Northwest University, Xi'an, P. R. China.; Pokaż więcej
Źródło:: Journal of separation science [J Sep Sci] 2021 Sep; Vol. 44 (17), pp. 3219-3228. Date of Electronic Publication: 2021 Jul 11.
Typ publikacji:: Journal Article
MeSH Terms:: Antitussive Agents/*isolation & purification
Drugs, Chinese Herbal/*isolation & purification
Plant Extracts/*isolation & purification
Receptors, Adrenergic, beta-2/*chemistry
Administration, Oral ; Antitussive Agents/administration & dosage ; Antitussive Agents/chemistry ; Chromatography, Affinity ; Drugs, Chinese Herbal/administration & dosage ; Drugs, Chinese Herbal/chemistry ; Humans ; Medicine, Chinese Traditional ; Molecular Docking Simulation ; Molecular Structure ; Plant Extracts/administration & dosage ; Plant Extracts/chemistry

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Skocz do pozycji: 15.

Tytuł:: Simultaneous LC-MS/MS bioanalysis of alkaloids, terpenoids, and flavonoids in rat plasma through salting-out-assisted liquid-liquid extraction after oral administration of extract from Tetradium ruticarpum and Glycyrrhiza uralensis: a sample preparation strategy to broaden analyte coverage of herbal medicines.
Autorzy:: Li M; Institute of Chinese Materia Medica, The MOE Key Laboratory for Standardization of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicines, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, China.
Wang H; Institute of Chinese Materia Medica, The MOE Key Laboratory for Standardization of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicines, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, China.
Huan X; Institute of Chinese Materia Medica, The MOE Key Laboratory for Standardization of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicines, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, China.
Cao N; Institute of Chinese Materia Medica, The MOE Key Laboratory for Standardization of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicines, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, China.
Guan H; Institute of Chinese Materia Medica, The MOE Key Laboratory for Standardization of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicines, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, China.
Zhang H; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Cheng X; Institute of Chinese Materia Medica, The MOE Key Laboratory for Standardization of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicines, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, China.
Wang C; Institute of Chinese Materia Medica, The MOE Key Laboratory for Standardization of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicines, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, China. .; Pokaż więcej
Źródło:: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2021 Sep; Vol. 413 (23), pp. 5871-5884. Date of Electronic Publication: 2021 Jul 31.
Typ publikacji:: Journal Article
MeSH Terms:: Herbal Medicine*
Alkaloids/*blood
Chromatography, Liquid/*methods
Evodia/*chemistry
Flavonoids/*blood
Glycyrrhiza uralensis/*chemistry
Liquid-Liquid Extraction/*methods
Plant Extracts/*administration & dosage
Tandem Mass Spectrometry/*methods
Terpenes/*blood
Administration, Oral ; Animals ; Female ; Limit of Detection ; Male ; Rats ; Rats, Sprague-Dawley ; Reference Standards

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Skocz do pozycji: 16.

Tytuł:: Evaluation of antibacterial and acute oral toxicity of Impatiens tinctoria A. Rich root extracts.
Autorzy:: Degu S; Traditional and Modern Medicine Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Abebe A; Traditional and Modern Medicine Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Gemeda N; Traditional and Modern Medicine Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Bitew A; School of Medical Laboratory Science, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Aug 11; Vol. 16 (8), pp. e0255932. Date of Electronic Publication: 2021 Aug 11 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Bacterial Agents/*chemistry
Impatiens/*chemistry
Plant Extracts/*chemistry
Administration, Oral ; Animals ; Anti-Bacterial Agents/isolation & purification ; Anti-Bacterial Agents/pharmacology ; Ethiopia ; Female ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Impatiens/metabolism ; Lethal Dose 50 ; Mice ; Microbial Sensitivity Tests ; Plant Extracts/pharmacology ; Plant Roots/chemistry ; Plant Roots/metabolism

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Skocz do pozycji: 17.

Tytuł:: Solanum nigrum Line inhibits osteoclast differentiation and suppresses bone mineral density reduction in the ovariectomy‑induced osteoporosis model.
Autorzy:: Kim JH; Department of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul 02‑447, Republic of Korea.
Shin H; Department of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul 02‑447, Republic of Korea.
Kim M; Department of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul 02‑447, Republic of Korea.
Kim S; Department of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul 02‑447, Republic of Korea.
Song K; Department of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul 02‑447, Republic of Korea.
Jung HS; Department of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul 02‑447, Republic of Korea.
Sohn Y; Department of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul 02‑447, Republic of Korea.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2021 Aug; Vol. 24 (2). Date of Electronic Publication: 2021 Jun 29.
Typ publikacji:: Journal Article
MeSH Terms:: Bone Density/*drug effects
Bone Density Conservation Agents/*pharmacology
Osteoclasts/*drug effects
Osteoporosis, Postmenopausal/*metabolism
Osteoporosis, Postmenopausal/*prevention & control
Plant Extracts/*pharmacology
Solanum nigrum/*chemistry
Actins/metabolism ; Administration, Oral ; Animals ; Bone Density Conservation Agents/administration & dosage ; Bone Density Conservation Agents/chemistry ; Bone Resorption/drug therapy ; Bone Resorption/metabolism ; Cancellous Bone/drug effects ; Cancellous Bone/metabolism ; Cathepsin K/metabolism ; Cell Differentiation/drug effects ; Disease Models, Animal ; Female ; Humans ; Mice ; Osteoblasts/drug effects ; Osteoclasts/cytology ; Osteoclasts/metabolism ; Osteoporosis, Postmenopausal/etiology ; Osteoporosis, Postmenopausal/pathology ; Ovariectomy/adverse effects ; Plant Extracts/administration & dosage ; Plant Extracts/chemistry ; Proto-Oncogene Proteins c-fos/metabolism ; RANK Ligand/metabolism ; RAW 264.7 Cells ; Rats, Sprague-Dawley ; Transcription Factors/metabolism

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Skocz do pozycji: 18.

Tytuł:: Formulation Effects in the Antioxidant Activity of Extract from the Leaves of Cymbopogon citratus (DC) Stapf.
Autorzy:: Sousa R; Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.
Figueirinha A; Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.; LAQV, REQUIMTE, Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.
Batista MT; Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.; CIEPQPF, FFUC, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.
Pina ME; Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.; CIEPQPF, FFUC, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Jul 27; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 27.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants/*chemistry
Cymbopogon/*chemistry
Drug Compounding/*methods
Plant Extracts/*chemistry
Plant Leaves/*chemistry
Administration, Oral ; Capsules ; Chromatography, High Pressure Liquid/methods ; Excipients/chemistry ; Flavonoids/analysis ; Gelatin/chemistry ; Polyphenols/analysis ; Tannins/analysis

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Skocz do pozycji: 19.

Tytuł:: Safety Evaluation of Standardized Extract of Curcuma longa (NR-INF-02): A 90-Day Subchronic Oral Toxicity Study in Rats.
Autorzy:: Murugan S; R&D Center, Natural Remedies Private Limited, Bengaluru, Karnataka, India.
Solanki H; Sa-FORD, Navi Mumbai, Maharashtra, India.
Purusothaman D; R&D Center, Natural Remedies Private Limited, Bengaluru, Karnataka, India.
Bethapudi B; R&D Center, Natural Remedies Private Limited, Bengaluru, Karnataka, India.
Ravalji M; Sa-FORD, Navi Mumbai, Maharashtra, India.
Mundkinajeddu D; R&D Center, Natural Remedies Private Limited, Bengaluru, Karnataka, India.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2021 Jul 14; Vol. 2021, pp. 6671853. Date of Electronic Publication: 2021 Jul 14 (Print Publication: 2021).
Typ publikacji:: Evaluation Study; Journal Article
MeSH Terms:: Toxicity Tests, Subchronic*
Curcuma/*chemistry
Plant Extracts/*adverse effects
Plant Extracts/*toxicity
Administration, Oral ; Animals ; Body Weight/drug effects ; Chromatography, High Pressure Liquid ; Curcuma/adverse effects ; Curcuma/toxicity ; Dose-Response Relationship, Drug ; Feeding Behavior/drug effects ; Female ; Hormones/metabolism ; Male ; Organ Size/drug effects ; Rats, Wistar ; Urinalysis ; Rats

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Skocz do pozycji: 20.

Tytuł:: Formulation and In Vitro Evaluation of Oral Capsules and Suspension from the Ethanolic Extract of Cola nitida Seeds for the Treatment of Diarrhea.
Autorzy:: Owusu FWA; Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Asare CO; Department of Pharmaceutics, School of Pharmacy, Central University, Miotso, Ghana.
Enstie P; Department of Herbal Medicine, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Adi-Dako O; Department of Pharmaceutics and Microbiology, School of Pharmacy, University of Ghana, Ghana.
Yeboah GN; Centre for Plant Medicine Research, Akuapem-Mampong, Ghana.
Kumadoh D; Centre for Plant Medicine Research, Akuapem-Mampong, Ghana.
Tetteh-Annor A; Department of Pharmaceutics, School of Pharmacy, Central University, Miotso, Ghana.
Amenuke EM; Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Karen M; Department of Pharmaceutics, School of Pharmacy, Central University, Miotso, Ghana.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2021 Jun 29; Vol. 2021, pp. 6630449. Date of Electronic Publication: 2021 Jun 29 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Drug Compounding*
Cola/*chemistry
Diarrhea/*drug therapy
Ethanol/*chemistry
Plant Extracts/*administration & dosage
Plant Extracts/*therapeutic use
Seeds/*chemistry
Administration, Oral ; Capsules ; Hydrogen-Ion Concentration ; Plant Extracts/pharmacology ; Rheology ; Rotation ; Suspensions ; Time Factors ; Viscosity

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