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Tytuł :
Comparative influences of dermal and inhalational routes of exposure on hazards of cleaning product ingredients among mammalian model organisms.
Autorzy :
Wang Z; Institute of Marine Sciences and Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou 515063, China. Electronic address: .
Wang YYL; Institute of Marine Sciences and Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou 515063, China.
Scott WC; Department of Environmental Science, Baylor University, Waco, TX, USA.
Williams ES; Department of Environmental Science, Baylor University, Waco, TX, USA.
Ciarlo M; EA Engineering, Science & Technology, Inc., Baltimore, MD, USA.
DeLeo P; American Cleaning Institute, Washington, DC, USA.
Brooks BW; Department of Environmental Science, Baylor University, Waco, TX, USA; School of Environment, Jinan University, Guangzhou 510632, China; Institute of Biomedical Studies, Baylor University, Waco, TX, USA. Electronic address: .
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Źródło :
Environment international [Environ Int] 2021 Dec; Vol. 157, pp. 106777. Date of Electronic Publication: 2021 Jul 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
No-Observed-Adverse-Effect Level*
Animals ; Dogs ; Guinea Pigs ; Lethal Dose 50 ; Mice ; Probability ; Rabbits ; Rats ; Risk Assessment ; Uncertainty
Czasopismo naukowe
Tytuł :
A 90-day subchronic toxicity study of Myrrh in F344 rats.
Autorzy :
Mitsumoto T; Division of Pathology, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan; Faculty of Animal Health Technology, Yamazaki University of Animal Health Technology, 4-7-2, Minami-osawa, Hachihoji, Tokyo, 192-0364, Japan.
Ishii Y; Division of Pathology, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan. Electronic address: .
Namiki M; Division of Pathology, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.
Nakamura K; Division of Pathology, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
Takasu S; Division of Pathology, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.
Ogawa K; Division of Pathology, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Dec; Vol. 127, pp. 105076. Date of Electronic Publication: 2021 Nov 04.
Typ publikacji :
Journal Article
MeSH Terms :
No-Observed-Adverse-Effect Level*
Commiphora/*toxicity
Flavoring Agents/*toxicity
Resins, Plant/*toxicity
Animals ; Dose-Response Relationship, Drug ; Female ; Hyalin/drug effects ; Kidney/drug effects ; Male ; Organ Size/drug effects ; Particle Size ; Random Allocation ; Rats ; Rats, Inbred F344
Czasopismo naukowe
Tytuł :
Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies.
Autorzy :
Lowe K; U.S. Environmental Protection Agency, Office of Pesticide Programs, Washington, DC, USA.
Dawson J; U.S. Environmental Protection Agency, Office of Chemical Safety and Pollution Prevention, Washington, DC, USA.
Phillips K; U.S. Environmental Protection Agency, Office of Research & Development, Durham, NC, USA.
Minucci J; U.S. Environmental Protection Agency, Office of Research & Development, Durham, NC, USA.
Wambaugh JF; U.S. Environmental Protection Agency, Office of Research & Development, Durham, NC, USA.
Qian H; ExxonMobil Biomedical Sciences, Inc., Annandale, NJ, USA.
Ramanarayanan T; Syngenta Ltd., Greensboro, NC, USA.
Egeghy P; U.S. Environmental Protection Agency, Office of Research & Development, Durham, NC, USA.
Ingle B; U.S. Environmental Protection Agency, Office of Pesticide Program, Durham, NC, USA.
Brunner R; U.S. Environmental Protection Agency, Office of Pesticide Program, Durham, NC, USA.
Mendez E; U.S. Environmental Protection Agency, Office of Pesticide Programs, Washington, DC, USA.
Embry M; Health and Environmental Sciences Institute, Washington, DC, USA. Electronic address: .
Tan YM; U.S. Environmental Protection Agency, Office of Pesticide Program, Durham, NC, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Dec; Vol. 127, pp. 105073. Date of Electronic Publication: 2021 Oct 29.
Typ publikacji :
Journal Article
MeSH Terms :
Animal Experimentation*
Dose-Response Relationship, Drug*
No-Observed-Adverse-Effect Level*
Toxicokinetics*
Environmental Exposure/*analysis
Animals ; Databases, Factual ; Humans ; Maximum Tolerated Dose ; Risk Assessment ; Toxicity Tests
Czasopismo naukowe
Tytuł :
Subchronic Toxicity Evaluation of Aluminum Oxide Nanoparticles in Rats Following 28-Day Repeated Oral Administration.
Autorzy :
Park SH; College of Veterinary Medicine, Chonnam National University, Gwangju, 61186, Republic of Korea.
Lim JO; College of Veterinary Medicine, Chonnam National University, Gwangju, 61186, Republic of Korea.
Kim WI; College of Veterinary Medicine, Chonnam National University, Gwangju, 61186, Republic of Korea.
Park SW; College of Veterinary Medicine, Chonnam National University, Gwangju, 61186, Republic of Korea.
Lee SJ; College of Veterinary Medicine, Chonnam National University, Gwangju, 61186, Republic of Korea.
Shin IS; College of Veterinary Medicine, Chonnam National University, Gwangju, 61186, Republic of Korea.
Moon C; College of Veterinary Medicine, Chonnam National University, Gwangju, 61186, Republic of Korea.
Kim JH; Bioenvironmental Science & Technology Division, Korea Institute of Toxicology, Gyeongnam, 52834, Republic of Korea.
Heo JD; Bioenvironmental Science & Technology Division, Korea Institute of Toxicology, Gyeongnam, 52834, Republic of Korea.
Kim JC; College of Veterinary Medicine, Chonnam National University, Gwangju, 61186, Republic of Korea. .
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Źródło :
Biological trace element research [Biol Trace Elem Res] 2022 Jul; Vol. 200 (7), pp. 3215-3226. Date of Electronic Publication: 2021 Sep 18.
Typ publikacji :
Journal Article
MeSH Terms :
Aluminum Oxide*/toxicity
Nanoparticles*/toxicity
Administration, Oral ; Animals ; Body Weight ; Female ; Male ; No-Observed-Adverse-Effect Level ; Organ Size ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Evaluation of 28-day repeated oral dose toxicity of aluminum chloride in rats.
Autorzy :
Lim JO; College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
Jung TY; College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
Lee SJ; College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
Park SW; College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
Kim WI; College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
Park SH; College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
Kim JH; Bioenvironmental Science & Technology Division, Korea Institute of Toxicology, Jinju, Republic of Korea.
Heo JD; Bioenvironmental Science & Technology Division, Korea Institute of Toxicology, Jinju, Republic of Korea.
Kim YB; Department of Advanced Toxicology Research, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Shin IS; College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
Kim JC; College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
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Źródło :
Drug and chemical toxicology [Drug Chem Toxicol] 2022 May; Vol. 45 (3), pp. 1088-1097. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Journal Article
MeSH Terms :
Liver*
Administration, Oral ; Aluminum Chloride/toxicity ; Animals ; Female ; Male ; No-Observed-Adverse-Effect Level ; Rats ; Rats, Sprague-Dawley ; Triglycerides
Czasopismo naukowe
Tytuł :
Update to RIFM fragrance ingredient safety assessment, 2,4-dimethylbenzyl acetate, CAS Registry Number 62346-96-7.
Autorzy :
Api AM; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Belsito D; Member Expert Panel for Fragrance Safety, Columbia University Medical Center, Department of Dermatology, 161 Fort Washington Ave., New York, NY, 10032, USA.
Botelho D; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Bruze M; Member Expert Panel for Fragrance Safety, Malmo University Hospital, Department of Occupational & Environmental Dermatology, Sodra Forstadsgatan 101, Entrance 47, Malmo, SE, 20502, Sweden.
Burton GA Jr; Member Expert Panel for Fragrance Safety, School of Natural Resources & Environment, University of Michigan, Dana Building G110, 440 Church St., Ann Arbor, MI, 58109, USA.
Cancellieri MA; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Chon H; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Dagli ML; Member Expert Panel for Fragrance Safety, University of Sao Paulo, School of Veterinary Medicine and Animal Science, Department of Pathology, Av. Prof. dr. Orlando Marques de Paiva, 87, Sao Paulo, CEP 05508-900, Brazil.
Date M; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Dekant W; Member Expert Panel for Fragrance Safety, University of Wuerzburg, Department of Toxicology, Versbacher Str. 9, 97078, Würzburg, Germany.
Deodhar C; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Fryer AD; Member Expert Panel for Fragrance Safety, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, OR, 97239, USA.
Jones L; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Joshi K; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Kumar M; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lapczynski A; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lavelle M; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lee I; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Liebler DC; Member Expert Panel for Fragrance Safety, Vanderbilt University School of Medicine, Department of Biochemistry, Center in Molecular Toxicology, 638 Robinson Research Building, 2200 Pierce Avenue, Nashville, TN, 37232-0146, USA.
Moustakas H; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Na M; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Penning TM; Member of Expert Panel for Fragrance Safety, University of Pennsylvania, Perelman School of Medicine, Center of Excellence in Environmental Toxicology, 1316 Biomedical Research Building (BRB) II/III, 421 Curie Boulevard, Philadelphia, PA, 19104-3083, USA.
Ritacco G; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Romine J; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Sadekar N; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Schultz TW; Member Expert Panel for Fragrance Safety, The University of Tennessee, College of Veterinary Medicine, Department of Comparative Medicine, 2407 River Dr., Knoxville, TN, 37996- 4500, USA.
Selechnik D; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Siddiqi F; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Sipes IG; Member Expert Panel for Fragrance Safety, Department of Pharmacology, University of Arizona, College of Medicine, 1501 North Campbell Avenue, P.O. Box 245050, Tucson, AZ, 85724-5050, USA.
Sullivan G; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA. Electronic address: .
Thakkar Y; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Tokura Y; Member Expert Panel for Fragrance Safety, The Journal of Dermatological Science (JDS), Editor-in-Chief, Professor and Chairman, Department of Dermatology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan.
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2022 Jul; Vol. 165 Suppl 1, pp. 113180. Date of Electronic Publication: 2022 May 26.
Typ publikacji :
Journal Article
MeSH Terms :
Perfume*/toxicity
Toxicity Tests*
Acetates ; Benzyl Compounds ; Consumer Product Safety ; DNA Damage ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical ; Endpoint Determination ; No-Observed-Adverse-Effect Level ; Odorants ; Registries ; Risk Assessment
Czasopismo naukowe
Tytuł :
RIFM fragrance ingredient safety assessment, benzoic acid, CAS Registry Number 65-85-0.
Autorzy :
Api AM; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Belsito D; Member Expert Panel for Fragrance Safety, Columbia University Medical Center, Department of Dermatology, 161 Fort Washington Ave., New York, NY, 10032, USA.
Botelho D; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Bruze M; Member Expert Panel for Fragrance Safety, Malmo University Hospital, Department of Occupational & Environmental Dermatology, Sodra Forstadsgatan 101, Entrance 47, Malmo, SE, 20502, Sweden.
Burton GA Jr; Member Expert Panel for Fragrance Safety, School of Natural Resources & Environment, University of Michigan, Dana Building G110, 440 Church St., Ann Arbor, MI, 58109, USA.
Cancellieri MA; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Chon H; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Dagli ML; Member Expert Panel for Fragrance Safety, University of Sao Paulo, School of Veterinary Medicine and Animal Science, Department of Pathology, Av. Prof. dr. Orlando Marques de Paiva, 87, Sao Paulo, CEP, 05508-900, Brazil.
Date M; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Dekant W; Member Expert Panel for Fragrance Safety, University of Wuerzburg, Department of Toxicology, Versbacher Str. 9, 97078, Würzburg, Germany.
Deodhar C; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Fryer AD; Member Expert Panel for Fragrance Safety, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, OR, 97239, USA.
Jones L; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Joshi K; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Kumar M; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lapczynski A; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lavelle M; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lee I; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Liebler DC; Member Expert Panel for Fragrance Safety, Vanderbilt University School of Medicine, Department of Biochemistry, Center in Molecular Toxicology, 638 Robinson Research Building, 2200 Pierce Avenue, Nashville, TN, 37232-0146, USA.
Moustakas H; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Na M; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Penning TM; Member of Expert Panel for Fragrance Safety, University of Pennsylvania, Perelman School of Medicine, Center of Excellence in Environmental Toxicology, 1316 Biomedical Research Building (BRB) II/III, 421 Curie Boulevard, Philadelphia, PA, 19104-3083, USA.
Ritacco G; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Romine J; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Sadekar N; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Schultz TW; Member Expert Panel for Fragrance Safety, The University of Tennessee, College of Veterinary Medicine, Department of Comparative Medicine, 2407 River Dr., Knoxville, TN, 37996- 4500, USA.
Selechnik D; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Siddiqi F; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Sipes IG; Member Expert Panel for Fragrance Safety, Department of Pharmacology, University of Arizona, College of Medicine, 1501 North Campbell Avenue, P.O. Box 245050, Tucson, AZ, 85724-5050, USA.
Sullivan G; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA. Electronic address: .
Thakkar Y; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Tokura Y; Member Expert Panel for Fragrance Safety, The Journal of Dermatological Science (JDS), Editor-in-Chief, Professor and Chairman, Department of Dermatology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan.
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2022 Jul; Vol. 165 Suppl 1, pp. 113143. Date of Electronic Publication: 2022 May 18.
Typ publikacji :
Journal Article
MeSH Terms :
Odorants*
Perfume*/toxicity
Benzoic Acid ; No-Observed-Adverse-Effect Level ; Registries
Czasopismo naukowe
Tytuł :
RIFM fragrance ingredient safety assessment, phenethyl propionate, CAS Registry Number 122-70-3.
Autorzy :
Api AM; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Belsito D; Member Expert Panel for Fragrance Safety, Columbia University Medical Center, Department of Dermatology, 161 Fort Washington Ave., New York, NY, 10032, USA.
Botelho D; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Bruze M; Member Expert Panel for Fragrance Safety, Malmo University Hospital, Department of Occupational & Environmental Dermatology, Sodra Forstadsgatan 101, Entrance 47, Malmo, SE-20502, Sweden.
Burton GA Jr; Member Expert Panel for Fragrance Safety, School of Natural Resources & Environment, University of Michigan, Dana Building G110, 440 Church St., Ann Arbor, MI, 58109, USA.
Cancellieri MA; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Chon H; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Dagli ML; Member Expert Panel for Fragrance Safety, University of Sao Paulo, School of Veterinary Medicine and Animal Science, Department of Pathology, Av. Prof. dr. Orlando Marques de Paiva, 87, Sao Paulo, CEP 05508-900, Brazil.
Date M; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Dekant W; Member Expert Panel for Fragrance Safety, University of Wuerzburg, Department of Toxicology, Versbacher Str. 9, 97078, Würzburg, Germany.
Deodhar C; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Fryer AD; Member Expert Panel for Fragrance Safety, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, OR, 97239, USA.
Jones L; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Joshi K; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Kumar M; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lapczynski A; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lavelle M; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lee I; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Liebler DC; Member Expert Panel for Fragrance Safety, Vanderbilt University School of Medicine, Department of Biochemistry, Center in Molecular Toxicology, 638 Robinson Research Building, 2200 Pierce Avenue, Nashville, TN, 37232-0146, USA.
Moustakas H; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Na M; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Penning TM; Member of Expert Panel for Fragrance Safety, University of Pennsylvania, Perelman School of Medicine, Center of Excellence in Environmental Toxicology, 1316 Biomedical Research Building (BRB) II/III, 421 Curie Boulevard, Philadelphia, PA, 19104-3083, USA.
Ritacco G; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Romine J; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Sadekar N; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Schultz TW; Member Expert Panel for Fragrance Safety, The University of Tennessee, College of Veterinary Medicine, Department of Comparative Medicine, 2407 River Dr., Knoxville, TN, 37996- 4500, USA.
Selechnik D; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Siddiqi F; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Sipes IG; Member Expert Panel for Fragrance Safety, Department of Pharmacology, University of Arizona, College of Medicine, 1501 North Campbell Avenue, P.O. Box 245050, Tucson, AZ, 85724-5050, USA.
Sullivan G; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA. Electronic address: .
Thakkar Y; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Tokura Y; Member Expert Panel for Fragrance Safety, The Journal of Dermatological Science (JDS), Editor-in-Chief, Professor and Chairman, Department of Dermatology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan.
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2022 Jul; Vol. 165 Suppl 1, pp. 113073. Date of Electronic Publication: 2022 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Perfume*/toxicity
Propionates*
No-Observed-Adverse-Effect Level ; Odorants ; Registries
Czasopismo naukowe
Tytuł :
Prenatal developmental toxicity study of 2,4-dichlorobenzyl alcohol in rats.
Autorzy :
Moon KN; Developmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea; OliX Pharmaceuticals, Inc., Suwon, Republic of Korea.
Baek SK; Developmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Kim W; Toxicological Pathology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Jeong JS; Developmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Lee BS; Toxicological Pathology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Quah Y; Developmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Lee J; Developmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Kim SY; Developmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Lee SJ; Developmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Kim KB; College of Pharmacy, Dankook University, Cheonan, Chungnam, Republic of Korea.
Yu WJ; Developmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2022 Jul; Vol. 132, pp. 105168. Date of Electronic Publication: 2022 Apr 14.
Typ publikacji :
Journal Article
MeSH Terms :
Abnormalities, Drug-Induced*/etiology
Placenta*
Animals ; Benzyl Alcohols ; Body Weight ; Female ; No-Observed-Adverse-Effect Level ; Pregnancy ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
A study of the genetic and prenatal developmental toxicity potential of lithothamnion sp .
Autorzy :
Ying Z; Institute of Toxicology, Shanxi Provincial Center for Disease Control and Prevention, Taiyuan, China.
Ruotao T; Institute of Toxicology, Shanxi Provincial Center for Disease Control and Prevention, Taiyuan, China.
Haili W; College of Life Science, Shanxi University, Taiyuan, China.
Shuqin L; Institute of Toxicology, Shanxi Provincial Center for Disease Control and Prevention, Taiyuan, China.
Linxiu B; Institute of Toxicology, Shanxi Provincial Center for Disease Control and Prevention, Taiyuan, China.
Xuemin L; Institute of Toxicology, Shanxi Provincial Center for Disease Control and Prevention, Taiyuan, China.
Qing L; Institute of Toxicology, Shanxi Provincial Center for Disease Control and Prevention, Taiyuan, China.
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Źródło :
Drug and chemical toxicology [Drug Chem Toxicol] 2022 Jul; Vol. 45 (4), pp. 1644-1651. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Journal Article
MeSH Terms :
Dietary Supplements*
Toxicity Tests*
Animals ; Female ; Humans ; Mammals ; Micronucleus Tests ; No-Observed-Adverse-Effect Level ; Pregnancy ; Salmonella typhimurium
Czasopismo naukowe
Tytuł :
Monte Carlo Models for Sub-Chronic Repeated-Dose Toxicity: Systemic and Organ-Specific Toxicity.
Autorzy :
Selvestrel G; Laboratory of Chemistry and Environmental Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milan, Italy.
Lavado GJ; Laboratory of Chemistry and Environmental Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milan, Italy.
Toropova AP; Laboratory of Chemistry and Environmental Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milan, Italy.
Toropov AA; Laboratory of Chemistry and Environmental Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milan, Italy.
Gadaleta D; Laboratory of Chemistry and Environmental Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milan, Italy.
Marzo M; Laboratory of Chemistry and Environmental Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milan, Italy.
Baderna D; Laboratory of Chemistry and Environmental Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milan, Italy.
Benfenati E; Laboratory of Chemistry and Environmental Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milan, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 14; Vol. 23 (12). Date of Electronic Publication: 2022 Jun 14.
Typ publikacji :
Journal Article
MeSH Terms :
Quantitative Structure-Activity Relationship*
Software*
Animals ; Computer Simulation ; Monte Carlo Method ; No-Observed-Adverse-Effect Level ; Rats
Czasopismo naukowe
Tytuł :
RIFM fragrance ingredient safety assessment, 1-spiro[4.5]dec-7-en-7-yl-4-penten-1-one, CAS Registry Number 224031-70-3.
Autorzy :
Api AM; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Belsito D; Member Expert Panel for Fragrance Safety, Columbia University Medical Center, Department of Dermatology, 161 Fort Washington Ave., New York, NY, 10032, USA.
Botelho D; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Bruze M; Member Expert Panel for Fragrance Safety, Malmo University Hospital, Department of Occupational & Environmental Dermatology, Sodra Forstadsgatan 101, Entrance 47, Malmo, SE-20502, Sweden.
Burton GA Jr; Member Expert Panel for Fragrance Safety, School of Natural Resources & Environment, University of Michigan, Dana Building G110, 440 Church St., Ann Arbor, MI, 58109, USA.
Cancellieri MA; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Chon H; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Dagli ML; Member Expert Panel for Fragrance Safety, University of Sao Paulo, School of Veterinary Medicine and Animal Science, Department of Pathology, Av. Prof. dr. Orlando Marques de Paiva, 87, Sao Paulo, CEP 05508-900, Brazil.
Date M; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Dekant W; Member Expert Panel for Fragrance Safety, University of Wuerzburg, Department of Toxicology, Versbacher Str. 9, 97078, Würzburg, Germany.
Deodhar C; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Fryer AD; Member Expert Panel for Fragrance Safety, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, OR, 97239, USA.
Jones L; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Joshi K; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Kumar M; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lapczynski A; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lavelle M; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lee I; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Liebler DC; Member Expert Panel for Fragrance Safety, Vanderbilt University School of Medicine, Department of Biochemistry, Center in Molecular Toxicology, 638 Robinson Research Building, 2200 Pierce Avenue, Nashville, TN, 37232-0146, USA.
Moustakas H; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Na M; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Penning TM; Member of Expert Panel for Fragrance Safety, University of Pennsylvania, Perelman School of Medicine, Center of Excellence in Environmental Toxicology, 1316 Biomedical Research Building (BRB) II/III, 421 Curie Boulevard, Philadelphia, PA, 19104-3083, USA.
Ritacco G; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Romine J; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Sadekar N; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Schultz TW; Member Expert Panel for Fragrance Safety, The University of Tennessee, College of Veterinary Medicine, Department of Comparative Medicine, 2407 River Dr., Knoxville, TN, 37996- 4500, USA.
Selechnik D; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Siddiqi F; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Sipes IG; Member Expert Panel for Fragrance Safety, Department of Pharmacology, University of Arizona, College of Medicine, 1501 North Campbell Avenue, P.O. Box 245050, Tucson, AZ, 85724-5050, USA.
Sullivan G; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA. Electronic address: .
Thakkar Y; Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Tokura Y; Member Expert Panel for Fragrance Safety, The Journal of Dermatological Science (JDS), Editor-in-Chief, Professor and Chairman, Department of Dermatology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan.
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2022 Jun; Vol. 164 Suppl 1, pp. 113104. Date of Electronic Publication: 2022 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Odorants*
Perfume*/toxicity
No-Observed-Adverse-Effect Level ; Registries ; Risk Assessment
Czasopismo naukowe
Tytuł :
An innovative study design with intermittent dosing to generate a GLP-regulatory package in preclinical species for long lasting molecule M5717, inhibitor of Plasmodium eukaryotic translation elongation factor 2.
Autorzy :
Hewitt P; The healthcare business of Merck KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany. Electronic address: .
Abla N; Ares Trading S.A., Route de Crassier 1, 1262 Eysins, Switzerland (an affiliate of Merck KGaA, Darmstadt, Germany); Medicines for Malaria Venture (MMV), Geneva, Switzerland.
Lignet F; The healthcare business of Merck KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany.
Oeuvray C; Ares Trading S.A., Route de Crassier 1, 1262 Eysins, Switzerland (an affiliate of Merck KGaA, Darmstadt, Germany).
Bagchus W; The healthcare business of Merck KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany.
Bebrevska L; Medicines for Malaria Venture (MMV), Geneva, Switzerland.
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2022 May 15; Vol. 443, pp. 116006. Date of Electronic Publication: 2022 Mar 31.
Typ publikacji :
Journal Article
MeSH Terms :
Antimalarials*/toxicity
Plasmodium*
Animals ; Dogs ; No-Observed-Adverse-Effect Level ; Peptide Elongation Factor 2 ; Rats ; Research Design
Czasopismo naukowe
Tytuł :
Hormetic dose responses induced by organic flame retardants in aquatic animals: Occurrence and quantification.
Autorzy :
Sun T; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS), Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai 264003, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China.
Ji C; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS), Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai 264003, PR China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, PR China; Center for Ocean Mega-Science, Chinese Academy of Sciences (CAS), Qingdao 266071, PR China.
Li F; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS), Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai 264003, PR China; Center for Ocean Mega-Science, Chinese Academy of Sciences (CAS), Qingdao 266071, PR China.
Wu H; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS), Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai 264003, PR China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, PR China; Center for Ocean Mega-Science, Chinese Academy of Sciences (CAS), Qingdao 266071, PR China. Electronic address: .
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Źródło :
The Science of the total environment [Sci Total Environ] 2022 May 10; Vol. 820, pp. 153295. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
MeSH Terms :
Flame Retardants*/toxicity
Hormesis*
Animals ; Dose-Response Relationship, Drug ; No-Observed-Adverse-Effect Level ; Risk Assessment
Czasopismo naukowe
Tytuł :
Genotoxicity, acute and subchronic toxicity evaluation of fermented Morinda officinalis.
Autorzy :
Tao Q; Infinitus (China) Co., Ltd., Guangzhou, 510623, China.
Peng D; South China Agricultural University, College of Food Science, Guangzhou, 510642, China.
Li P; South China Agricultural University, College of Food Science, Guangzhou, 510642, China.
Lai L; South China Agricultural University, College of Food Science, Guangzhou, 510642, China.
Li W; Infinitus (China) Co., Ltd., Guangzhou, 510623, China. Electronic address: .
Du B; South China Agricultural University, College of Food Science, Guangzhou, 510642, China. Electronic address: .
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2022 May; Vol. 163, pp. 113003. Date of Electronic Publication: 2022 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Morinda*/toxicity
Rubiaceae*
Animals ; Mammals ; Mice ; Mutagenicity Tests/methods ; No-Observed-Adverse-Effect Level ; Plant Extracts ; Rats ; Rats, Sprague-Dawley ; Toxicity Tests, Acute/methods ; Toxicity Tests, Subchronic/methods
Czasopismo naukowe
Tytuł :
RIFM fragrance ingredient safety assessment, menthol, CAS Registry Number 89-78-1.
Autorzy :
Api AM; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Belsito D; Member Expert Panel for Fragrance Safety, Columbia University Medical Center, Department of Dermatology, 161 Fort Washington Ave., New York, NY, 10032, USA.
Botelho D; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Bruze M; Member Expert Panel for Fragrance Safety, Malmo University Hospital, Department of Occupational & Environmental Dermatology, Sodra Forstadsgatan 101, Entrance 47, Malmo, SE-20502, Sweden.
Burton GA Jr; Member Expert Panel for Fragrance Safety, School of Natural Resources & Environment, University of Michigan, Dana Building G110, 440 Church St., Ann Arbor, MI, 58109, USA.
Cancellieri MA; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Chon H; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Dagli ML; Member Expert Panel for Fragrance Safety, University of Sao Paulo, School of Veterinary Medicine and Animal Science, Department of Pathology, Av. Prof. dr. Orlando Marques de Paiva, 87, Sao Paulo CEP, 05508-900, Brazil.
Date M; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Dekant W; Member Expert Panel for Fragrance Safety, University of Wuerzburg, Department of Toxicology, Versbacher Str. 9, 97078, Würzburg, Germany.
Deodhar C; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Fryer AD; Member Expert Panel for Fragrance Safety, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, OR, 97239, USA.
Jones L; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Joshi K; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Kumar M; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lapczynski A; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lavelle M; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Lee I; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Liebler DC; Member Expert Panel for Fragrance Safety, Vanderbilt University School of Medicine, Department of Biochemistry, Center in Molecular Toxicology, 638 Robinson Research Building, 2200 Pierce Avenue, Nashville, TN, 37232-0146, USA.
Moustakas H; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Na M; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Penning TM; Member of Expert Panel for Fragrance Safety, University of Pennsylvania, Perelman School of Medicine, Center of Excellence in Environmental Toxicology, 1316 Biomedical Research Building (BRB) II/III, 421 Curie Boulevard, Philadelphia, PA, 19104-3083, USA.
Ritacco G; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Romine J; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Sadekar N; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Schultz TW; Member Expert Panel for Fragrance Safety, The University of Tennessee, College of Veterinary Medicine, Department of Comparative Medicine, 2407 River Dr., Knoxville, TN, 37996- 4500, USA.
Selechnik D; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Siddiqi F; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Sipes IG; Member Expert Panel for Fragrance Safety, Department of Pharmacology, University of Arizona, College of Medicine, 1501 North Campbell Avenue, P.O. Box 245050, Tucson, AZ, 85724-5050, USA.
Sullivan G; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA. Electronic address: .
Thakkar Y; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
Tokura Y; Member Expert Panel for Fragrance Safety, The Journal of Dermatological Science (JDS), Department of Dermatology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan.
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2022 May; Vol. 163 Suppl 1, pp. 112927. Date of Electronic Publication: 2022 Mar 19.
Typ publikacji :
Journal Article
MeSH Terms :
Odorants*
Perfume*/toxicity
Menthol/toxicity ; No-Observed-Adverse-Effect Level ; Registries
Czasopismo naukowe
Tytuł :
In-vivo and in-silico toxicity studies of daidzein: an isoflavone from soy.
Autorzy :
Laddha AP; Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's NMIMS, Mumbai, India.
Murugesan S; Department of Pharmacy, Birla Institute of Technology and Science Pilani, Pilani, India.
Kulkarni YA; Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's NMIMS, Mumbai, India.
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Źródło :
Drug and chemical toxicology [Drug Chem Toxicol] 2022 May; Vol. 45 (3), pp. 1408-1416. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
Isoflavones*/toxicity
Animals ; Mice ; No-Observed-Adverse-Effect Level ; Rats ; Reproduction ; Soybeans/toxicity
Czasopismo naukowe
Tytuł :
Benchmark dose modelling in regulatory ecotoxicology, a potential tool in pest management.
Autorzy :
Jensen SM; Department of Plant and Environmental Sciences, University of Copenhagen, Taastrup, Denmark.
Kluxen FM; ADAMA Deutschland GmbH, Cologne, Germany.
Ritz C; National Institute of Public Health, University of Southern Denmark, Odense, Denmark.
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Źródło :
Pest management science [Pest Manag Sci] 2022 May; Vol. 78 (5), pp. 1772-1779. Date of Electronic Publication: 2021 Dec 31.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Benchmarking*
Pesticides*/toxicity
Dose-Response Relationship, Drug ; Ecotoxicology ; No-Observed-Adverse-Effect Level ; Pest Control ; Risk Assessment/methods
Czasopismo naukowe
Tytuł :
Elucidation of the neurological effects of clothianidin exposure at the no-observed-adverse-effect level (NOAEL) using two-photon microscopy in vivo imaging.
Autorzy :
Nishi M; Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Hyogo, Japan.
Sugio S; Department of Anatomy and Molecular Cell Biology, Graduate School of Medicine, Nagoya University, Aichi, Japan.
Hirano T; Life Science Research Center, University of Toyama, Toyama, Japan.
Kato D; Department of Anatomy and Molecular Cell Biology, Graduate School of Medicine, Nagoya University, Aichi, Japan.
Wake H; Department of Anatomy and Molecular Cell Biology, Graduate School of Medicine, Nagoya University, Aichi, Japan.
Shoda A; Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Hyogo, Japan.
Murata M; Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Hyogo, Japan.
Ikenaka Y; Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.; Translational Research Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.; One Health Research Center, Hokkaido University, Hokkaido, Japan.; Water Research Group, Unit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa.
Tabuchi Y; Life Science Research Center, University of Toyama, Toyama, Japan.
Mantani Y; Laboratory of Histophysiology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Hyogo, Japan.
Yokoyama T; Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Hyogo, Japan.
Hoshi N; Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Hyogo, Japan.
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Źródło :
The Journal of veterinary medical science [J Vet Med Sci] 2022 Apr 15; Vol. 84 (4), pp. 585-592. Date of Electronic Publication: 2022 Mar 10.
Typ publikacji :
Journal Article
MeSH Terms :
Insecticides*/toxicity
Microscopy*/veterinary
Animals ; Guanidines ; Mammals ; Mice ; Neonicotinoids/toxicity ; No-Observed-Adverse-Effect Level ; Thiazoles
Czasopismo naukowe

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