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Wyszukujesz frazę ""Age of Onset"" wg kryterium: Temat


Tytuł :
Association of systemic lupus erythematosus (SLE) genetic susceptibility loci with lupus nephritis in childhood-onset and adult-onset SLE.
Autorzy :
Webber D; Division of Rheumatology, Department of Pediatrics, University of Toronto, Toronto, Canada.
Cao J; Genetics & Genome Biology, Research Institute, SickKids Hospital, Toronto, Canada.
Dominguez D; Division of Rheumatology, Department of Pediatrics, University of Toronto, Toronto, Canada.
Gladman DD; Krembil Research Institute, Toronto Western Hospital, Toronto, Canada.
Levy DM; Division of Rheumatology, Department of Pediatrics, University of Toronto, Toronto, Canada.
Ng L; Division of Rheumatology, Department of Pediatrics, University of Toronto, Toronto, Canada.
Paterson AD; Genetics & Genome Biology, Research Institute, SickKids Hospital, Toronto, Canada.
Touma Z; Krembil Research Institute, Toronto Western Hospital, Toronto, Canada.
Urowitz MB; Krembil Research Institute, Toronto Western Hospital, Toronto, Canada.
Wither JE; Krembil Research Institute, Toronto Western Hospital, Toronto, Canada.
Silverman ED; Division of Rheumatology, Department of Pediatrics, University of Toronto, Toronto, Canada.; Division of Translational Medicine Research Institute, Toronto, Canada.
Hiraki LT; Division of Rheumatology, Department of Pediatrics, University of Toronto, Toronto, Canada.; Child Health Evaluative Sciences, Research Institute, SickKids Hospital, Toronto, Canada.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2020 Jan 01; Vol. 59 (1), pp. 90-98.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Age of Onset*
Genetic Loci/*genetics
Genetic Predisposition to Disease/*genetics
Lupus Erythematosus, Systemic/*genetics
Lupus Nephritis/*genetics
Adolescent ; Adult ; Child ; European Continental Ancestry Group/genetics ; Female ; Genetic Predisposition to Disease/ethnology ; Genotype ; Humans ; Logistic Models ; Lupus Erythematosus, Systemic/ethnology ; Lupus Nephritis/ethnology ; Male ; Odds Ratio ; Polymorphism, Single Nucleotide/genetics ; Risk Factors ; Young Adult
Czasopismo naukowe
Tytuł :
The myositis clinical phenotype associated with anti-Zo autoantibodies: a case series of nine UK patients.
Autorzy :
Tansley SL; Department of Pharmacy and Pharmacology, The University of Bath, Bath.
Betteridge Z; Department of Pharmacy and Pharmacology, The University of Bath, Bath.
Lu H; Department of Pharmacy and Pharmacology, The University of Bath, Bath.
Davies E; Department of Rheumatology, North Bristol NHS Trust, Bristol.
Rothwell S; Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester.
New PP; MRC/ARUK Centre for Integrated Research into Musculoskeletal Ageing, University of Liverpool, Liverpool.
Chinoy H; Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester.; National Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, The University of Manchester, Manchester.; Department of Rheumatology, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford.
Gordon P; Department of Rheumatology, Kings College, London.
Gunawardena H; Department of Rheumatology, North Bristol NHS Trust, Bristol.
Lloyd M; Department of Rheumatology, Frimley Park NHS Foundation Trust, Surrey.
Stratton R; UCL Division of Medicine, Centre for Rheumatology and Connective Tissue Diseases, London, UK.
Cooper R; MRC/ARUK Centre for Integrated Research into Musculoskeletal Ageing, University of Liverpool, Liverpool.
McHugh NJ; Department of Pharmacy and Pharmacology, The University of Bath, Bath.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2020 Jul 01; Vol. 59 (7), pp. 1626-1631.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoantibodies/*blood
Myositis/*diagnosis
Phenylalanine-tRNA Ligase/*immunology
Adult ; Age of Onset ; Aged ; Female ; Humans ; Male ; Middle Aged ; Myositis/blood ; Myositis/immunology ; Phenotype ; Retrospective Studies ; United Kingdom
Czasopismo naukowe
Tytuł :
Smoking in spondyloarthritis: unravelling the complexities.
Autorzy :
Zhao SS; Musculoskeletal biology I, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool.; Department of Academic Rheumatology, Liverpool University Hospitals, Liverpool.
Goodson NJ; Musculoskeletal biology I, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool.; Department of Academic Rheumatology, Liverpool University Hospitals, Liverpool.
Robertson S; Department of Academic Rheumatology, Liverpool University Hospitals, Liverpool.
Gaffney K; Department of Rheumatology, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, UK.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2020 Jul 01; Vol. 59 (7), pp. 1472-1481.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Arthritis, Psoriatic/*epidemiology
Smoking/*epidemiology
Age of Onset ; Humans ; Protective Factors ; Psoriasis/epidemiology ; Risk Factors ; Severity of Illness Index ; Smoking Cessation ; Spondylarthropathies/epidemiology
Czasopismo naukowe
Tytuł :
Prepregnancy Diabetes and Perinatal Mental Illness: A Population-Based Latent Class Analysis.
Autorzy :
Brown HK
Cairncross ZF
Lipscombe LL
Wilton AS
Dennis CL
Ray JG
Guttmann A
Vigod SN
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Źródło :
American journal of epidemiology [Am J Epidemiol] 2020 Jun 01; Vol. 189 (6), pp. 573-582.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Postpartum Period*
Diabetes Mellitus/*epidemiology
Mental Disorders/*epidemiology
Pregnancy Complications/*epidemiology
Adolescent ; Adult ; Age of Onset ; Comorbidity ; Female ; Humans ; Latent Class Analysis ; Middle Aged ; Ontario/epidemiology ; Pregnancy ; Young Adult
Czasopismo naukowe
Tytuł :
Predictors of Early Onset Neonatal Sepsis among Neonates in Dodoma, Tanzania: A Case Control Study.
Autorzy :
Masanja PP; Department of Clinical Nursing and Midwifery, College of Health Sciences, University of Dodoma, PO Box 359, Dodoma, Tanzania.
Kibusi SM; Department of Clinical Nursing and Midwifery, College of Health Sciences, University of Dodoma, PO Box 359, Dodoma, Tanzania.
Mkhoi ML; Department of Clinical Medicine, College of Health Sciences, University of Dodoma, PO Box 395, Dodoma, Tanzania.
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Źródło :
Journal of tropical pediatrics [J Trop Pediatr] 2020 Jun 01; Vol. 66 (3), pp. 257-266.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neonatal Sepsis/*diagnosis
Adult ; Age of Onset ; Birth Weight ; Case-Control Studies ; Chorioamnionitis/epidemiology ; Female ; Gestational Age ; Humans ; Infant, Newborn ; Intensive Care, Neonatal ; Male ; Maternal Age ; Mothers ; Neonatal Sepsis/epidemiology ; Parturition ; Pregnancy ; Tanzania/epidemiology
Czasopismo naukowe
Tytuł :
A patient with stimulator of interferon genes-associated vasculopathy with onset in infancy without skin vasculopathy.
Autorzy :
Raffaele CGL; Division of Rheumatology, IRCCS, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Messia V; Division of Rheumatology, IRCCS, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Moneta G; Division of Rheumatology, IRCCS, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Caiello I; Division of Rheumatology, IRCCS, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Federici S; Division of Rheumatology, IRCCS, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Pardeo M; Division of Rheumatology, IRCCS, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Bracaglia C; Division of Rheumatology, IRCCS, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
De Benedetti F; Division of Rheumatology, IRCCS, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Insalaco A; Division of Rheumatology, IRCCS, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2020 Apr 01; Vol. 59 (4), pp. 905-907.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Lung Diseases, Interstitial/*diagnosis
Membrane Proteins/*genetics
Skin Diseases, Vascular/*diagnosis
Vascular Diseases/*diagnosis
Age of Onset ; Anemia ; Antibodies, Antineutrophil Cytoplasmic/immunology ; Antibodies, Antinuclear/immunology ; Arthralgia/drug therapy ; Arthralgia/genetics ; Arthralgia/immunology ; Blood Sedimentation ; Bronchiectasis/diagnosis ; Bronchiectasis/drug therapy ; Bronchiectasis/genetics ; Bronchiectasis/immunology ; C-Reactive Protein/immunology ; Child, Preschool ; Cough ; Failure to Thrive ; Female ; Fever/drug therapy ; Fever/genetics ; Fever/immunology ; High-Throughput Nucleotide Sequencing ; Humans ; Immunoglobulin G/immunology ; Immunosuppressive Agents/therapeutic use ; Infant ; Interferon Type I ; Lung Diseases, Interstitial/drug therapy ; Lung Diseases, Interstitial/genetics ; Lung Diseases, Interstitial/immunology ; Multiple Pulmonary Nodules/diagnosis ; Multiple Pulmonary Nodules/drug therapy ; Multiple Pulmonary Nodules/genetics ; Multiple Pulmonary Nodules/immunology ; Osteoarthropathy, Primary Hypertrophic ; Sequence Analysis, DNA ; Serum Amyloid A Protein ; Skin Diseases, Vascular/drug therapy ; Skin Diseases, Vascular/genetics ; Skin Diseases, Vascular/immunology ; Vascular Diseases/drug therapy ; Vascular Diseases/genetics ; Vascular Diseases/immunology
Czasopismo naukowe
Tytuł :
Response to: Variation of the age at onset of pancreatic cancer according to tobacco smoking and family history.
Autorzy :
Molina-Montes E; Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Center (CNIO), Madrid, CIBERONC, Spain.
Malats N; Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Center (CNIO), Madrid, CIBERONC, Spain.
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Corporate Authors :
PanGenEU Study Investigators
Źródło :
International journal of epidemiology [Int J Epidemiol] 2018 Aug 01; Vol. 47 (4), pp. 1358-1359.
Typ publikacji :
Letter; Comment
MeSH Terms :
Age of Onset*
Pancreatic Neoplasms*
Humans ; Tobacco Smoking
Opinia redakcyjna
Tytuł :
Variation of the age at onset of pancreatic cancer according to tobacco smoking and family history.
Autorzy :
Maisonneuve P; Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy.
Lowenfels AB; Department of Surgery and Department of Family Medicine, New York Medical College, Valhalla, NY, USA.
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Źródło :
International journal of epidemiology [Int J Epidemiol] 2018 Aug 01; Vol. 47 (4), pp. 1357.
Typ publikacji :
Letter; Comment
MeSH Terms :
Age of Onset*
Pancreatic Neoplasms*
Humans ; Smoking ; Tobacco Smoking
Opinia redakcyjna
Tytuł :
Human Plasma BDNF Is Associated With Amygdala-Prefrontal Cortex Functional Connectivity and Problem Drinking Behaviors.
Autorzy :
Gorka SM; Department of Psychiatry, University of Illinois-Chicago, Chicago, Illinois.; Center for Alcohol Research in Epigenetics (CARE), University of Illinois-Chicago, Chicago, Illinois.; Department of Psychology, University of Illinois-Chicago, Chicago, Illinois.
Teppen T; Department of Psychiatry, University of Illinois-Chicago, Chicago, Illinois.; Center for Alcohol Research in Epigenetics (CARE), University of Illinois-Chicago, Chicago, Illinois.; Jesse Brown VA Medical Center, Chicago, Illinois.
Radoman M; Department of Psychiatry, University of Illinois-Chicago, Chicago, Illinois.
Phan KL; Department of Psychiatry, University of Illinois-Chicago, Chicago, Illinois.; Department of Psychology, University of Illinois-Chicago, Chicago, Illinois.; Jesse Brown VA Medical Center, Chicago, Illinois.
Pandey SC; Department of Psychiatry, University of Illinois-Chicago, Chicago, Illinois.; Center for Alcohol Research in Epigenetics (CARE), University of Illinois-Chicago, Chicago, Illinois.; Jesse Brown VA Medical Center, Chicago, Illinois.
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Źródło :
The international journal of neuropsychopharmacology [Int J Neuropsychopharmacol] 2020 Mar 10; Vol. 23 (1), pp. 1-11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Alcoholism*/blood
Alcoholism*/epidemiology
Alcoholism*/physiopathology
Anxiety*/blood
Anxiety*/epidemiology
Anxiety*/physiopathology
Binge Drinking*/blood
Binge Drinking*/epidemiology
Binge Drinking*/physiopathology
Connectome*
Amygdala/*physiopathology
Brain-Derived Neurotrophic Factor/*blood
Prefrontal Cortex/*physiopathology
Adult ; Age of Onset ; Amygdala/diagnostic imaging ; Avoidance Learning/physiology ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Prefrontal Cortex/diagnostic imaging ; Young Adult
Czasopismo naukowe
Tytuł :
Smoking, drinking, diet and physical activity-modifiable lifestyle risk factors and their associations with age to first chronic disease.
Autorzy :
Ng R; Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Sutradhar R; Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.
Yao Z; Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.
Wodchis WP; Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.; Institute for Better Health, Trillium Health Partners, Mississauga, ON, Canada.
Rosella LC; Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.; Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.
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Źródło :
International journal of epidemiology [Int J Epidemiol] 2020 Feb 01; Vol. 49 (1), pp. 113-130.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diet*
Exercise*
Sedentary Behavior*
Alcohol Drinking/*adverse effects
Chronic Disease/*epidemiology
Smoking/*adverse effects
Adult ; Age of Onset ; Aged ; Aged, 80 and over ; Alcohol Drinking/epidemiology ; Body Mass Index ; Cardiovascular Diseases/epidemiology ; Comorbidity ; Diabetes Mellitus, Type 2/epidemiology ; Female ; Health Surveys ; Humans ; Incidence ; Life Style ; Male ; Middle Aged ; Obesity/epidemiology ; Ontario/epidemiology ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Risk Factors ; Smoking/epidemiology ; Tobacco Smoking/adverse effects ; Tobacco Smoking/epidemiology
Czasopismo naukowe
Tytuł :
Early-Onset Dementia in War Veterans: Brain Polypathology and Clinicopathologic Complexity.
Autorzy :
Iacono D; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; Department of Neurology, F. Edward Hébert School of Medicine, Uniformed Services University (USU), Bethesda, Maryland.; Department of Pathology, F. Edward Hébert School of Medicine, Uniformed Services University (USU), Bethesda, Maryland.; The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF), Bethesda, Maryland.; Neurodegenerative Clinics, National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, Maryland.
Lee P; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF), Bethesda, Maryland.
Edlow BL; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; Department of Neurology, Center for Neurotechnology and Neurorecovery (BLE) and Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging.
Gray N; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF), Bethesda, Maryland.
Fischl B; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; Department of Neurology, Center for Neurotechnology and Neurorecovery (BLE) and Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging.; Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Department of Radiology, Harvard Medical School, Boston, Massachusetts.; Harvard-MIT Program in Health Sciences and Technology (HST)/Computer Science & Artificial Intelligence Lab (CSAIL), MIT, Cambridge, Massachusetts.
Kenney K; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; Department of Neurology, F. Edward Hébert School of Medicine, Uniformed Services University (USU), Bethesda, Maryland.
Lew HL; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; Department of Communication Sciences and Disorders, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, Hawaii.
Lozanoff S; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; Department of Anatomy, Biochemistry and Physiology, John A. Burns. School of Medicine, University of Hawaii, Honolulu, Hawaii.
Liacouras P; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; Department of Radiology and Radiological Sciences, F. Edward Hébert School of Medicine, Uniformed Services University (USU), Bethesda, Maryland.
Lichtenberger J; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; Department of Rehabilitation Medicine (KD-O) and Department of Neurology (KD-O), Icahn School of Medicine at Mount Sinai, New York City, New York; Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, Richmond, Virginia.
Dams-O'Connor K; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.
Cifu D; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; Department of Veterans Affairs, Chronic Effects of NeuroTrauma Consortium (CENC), Richmond, Virginia.; DoD Brain Health Research Program, Blast Injury Research Program Coordinating Office, Research and Technology United States Army Medical Research and Materiel Command, Fort Detrick, Maryland.
Hinds SR; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; Chronic Effects of NeuroTrauma Consortium (CENC), Fort Detrick, Maryland.
Perl DP; Brain Tissue Repository & Neuropathology Core, Center for Neuroscience and Regenerative Medicine (CNRM), Uniformed Services University (USU), Bethesda, Maryland.; Department of Pathology, F. Edward Hébert School of Medicine, Uniformed Services University (USU), Bethesda, Maryland.
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Źródło :
Journal of neuropathology and experimental neurology [J Neuropathol Exp Neurol] 2020 Feb 01; Vol. 79 (2), pp. 144-162.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*pathology
Dementia/*pathology
Age of Onset ; Aged ; Brain Injuries, Traumatic/complications ; Brain Injuries, Traumatic/pathology ; Dementia/complications ; Humans ; Membrane Glycoproteins ; Middle Aged ; Plaque, Amyloid/complications ; Plaque, Amyloid/pathology ; Receptors, Interleukin-1 ; Veterans
Czasopismo naukowe
Tytuł :
Hospital admissions and mortality in the 15 years after a first-time hospital contact with an alcohol problem: a prospective cohort study using the entire Danish population.
Autorzy :
Askgaard G; National Institute of Public Health, University of Southern Denmark, Copenhagen K, Denmark.; Gastro Unit, Copenhagen University Hospital, Bispebjerg Hospital, Copenhagen N, Denmark.
Leon DA; Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Sciences, London School of Hygiene & Tropical Medicine, London, UK.; Department of Community Medicine, UiT Arctic University of Norway, Tromsø, Norway.
Deleuran T; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus C, Denmark.
Tolstrup JS; National Institute of Public Health, University of Southern Denmark, Copenhagen K, Denmark.
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Źródło :
International journal of epidemiology [Int J Epidemiol] 2020 Feb 01; Vol. 49 (1), pp. 94-102.
Typ publikacji :
Journal Article
MeSH Terms :
Alcohol Drinking/*adverse effects
Alcohol-Related Disorders/*mortality
Chronic Disease/*epidemiology
Hospitalization/*statistics & numerical data
Mental Disorders/*epidemiology
Adult ; Age Distribution ; Age of Onset ; Aged ; Alcohol-Related Disorders/diagnosis ; Alcohol-Related Disorders/therapy ; Alcoholism/diagnosis ; Cause of Death ; Cohort Studies ; Comorbidity ; Denmark/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł :
Clinical Situation, Therapy, and Follow-Up of Adult Craniopharyngioma.
Autorzy :
Mende KC; Department of Neurosurgery, Hamburg University Medical Center, Hamburg, Germany.
Kellner T; Department of Neurosurgery, Hamburg University Medical Center, Hamburg, Germany.
Petersenn S; ENDOC Praxis für Endokrinologie, Andrologie und medikamentöse Tumortherapie, Hamburg, Germany.
Honegger J; Department of Neurosurgery, University of Tuebingen, Tuebingen, Germany.
Evangelista-Zamora R; Department of Neurosurgery, University of Tuebingen, Tuebingen, Germany.
Droste M; Medicover Oldenburg MVZ, Oldenburg, Germany.
Stalla G; Max-Planck-Institut für Psychiatrie, Munich, Germany.
Deutschbein T; Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital Würzburg, Würzburg, Germany.
Wang Y; Vivantes Klinikum im Friedrichshain, Berlin, Germany.
Moskopp D; Vivantes Klinikum im Friedrichshain, Berlin, Germany.
Knappe U; Department of Neurosurgery, Johannes Wesling Klinikum Minden, Ruhr University Bochum, Minden, Germany.
Schilbach K; Ludwig-Maximilians-University of Munich, Department of Internal Medicine IV, Munich, Germany.
Flitsch J; Department of Neurosurgery, Hamburg University Medical Center, Hamburg, Germany.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2020 Jan 01; Vol. 105 (1).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Craniopharyngioma*/diagnosis
Craniopharyngioma*/epidemiology
Craniopharyngioma*/therapy
Pituitary Neoplasms*/diagnosis
Pituitary Neoplasms*/epidemiology
Pituitary Neoplasms*/therapy
Adolescent ; Adult ; Age of Onset ; Aged ; Aged, 80 and over ; Cohort Studies ; Female ; Follow-Up Studies ; Germany/epidemiology ; Humans ; Male ; Middle Aged ; Neurosurgical Procedures/adverse effects ; Neurosurgical Procedures/statistics & numerical data ; Postoperative Complications/epidemiology ; Quality of Life ; Retrospective Studies ; Sphenoid Bone/surgery ; Young Adult
Czasopismo naukowe
Tytuł :
Risk of progressive chronic kidney disease in individuals with early-onset type 2 diabetes: a prospective cohort study.
Autorzy :
Liu JJ; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore.
Liu S; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore.
Gurung RL; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore.
Ang K; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore.
Tang WE; Department of Medicine, National Healthcare Group Polyclinics, Singapore.
Sum CF; Diabetes Centre, Khoo Teck Puat Hospital, Singapore.
Tavintharan S; Diabetes Centre, Khoo Teck Puat Hospital, Singapore.
Lim SC; Diabetes Centre, Khoo Teck Puat Hospital, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
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Źródło :
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2020 Jan 01; Vol. 35 (1), pp. 115-121.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 2/*complications
Diabetic Nephropathies/*etiology
Renal Insufficiency, Chronic/*etiology
Adult ; Age of Onset ; Albuminuria/etiology ; Albuminuria/pathology ; Diabetic Nephropathies/pathology ; Disease Progression ; Female ; Glomerular Filtration Rate ; Humans ; Male ; Middle Aged ; Prospective Studies ; Renal Insufficiency, Chronic/pathology ; Risk Factors
Czasopismo naukowe
Tytuł :
Constructing disease onset signatures using multi-dimensional network-structured biomarkers.
Autorzy :
Li X; Statistics and Decision Sciences, Janssen Research & Development, LLC, Raritan, NJ, USA.
Zeng D; Department of Psychiatric, University of North Carolina, Chapel Hill, NC, USA.
Marder K; Department of Biostatistics, Mailman School of Public Health, Columbia University, 722 W 168th Street, New York, NY, USA.
Wang Y; Department of Biostatistics, Mailman School of Public Health, Columbia University, 722 W 168th Street, New York, NY, USA.
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Źródło :
Biostatistics (Oxford, England) [Biostatistics] 2020 Jan 01; Vol. 21 (1), pp. 122-138.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Biomarkers*
Models, Statistical*
Huntington Disease/*diagnosis
Age of Onset ; Computer Simulation ; Humans ; Huntington Disease/diagnostic imaging ; Huntington Disease/epidemiology ; Neuroimaging
Czasopismo naukowe
Tytuł :
Skeletal Effects of Levothyroxine for Subclinical Hypothyroidism in Older Adults: A TRUST Randomized Trial Nested Study.
Autorzy :
Gonzalez Rodriguez E; Center of Bone Diseases, Rheumatology Unit, Bone and Joint Department, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Service of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Stuber M; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Del Giovane C; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Feller M; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.; Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Collet TH; Service of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Löwe AL; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.; Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Blum MR; Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
van Vliet NA; Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.
van Heemst D; Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.
Kearney PM; School of Public Health, University College Cork, Cork, Ireland.
Gussekloo J; Departments of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands.
Mooijaart S; Departments of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands.
Westendorp RGJ; Department of Public Health and Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark.
Stott DJ; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Aeberli D; Department of Rheumatology and Clinical Immunology/Allergology, Inselspital, Bern University Hospital, Bern, Switzerland.
Bauer DC; Departments of Medicine, Epidemiology and Biostatistics, University of California, San Francisco, US.
Hans D; Center of Bone Diseases, Rheumatology Unit, Bone and Joint Department, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Rodondi N; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.; Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2020 Jan 01; Vol. 105 (1).
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone and Bones/*drug effects
Hypothyroidism/*drug therapy
Thyroxine/*therapeutic use
Age of Onset ; Aged ; Aged, 80 and over ; Asymptomatic Diseases ; Bone Density/drug effects ; Bone Remodeling/drug effects ; Bone and Bones/physiology ; Double-Blind Method ; Female ; Hormone Replacement Therapy ; Humans ; Hypothyroidism/epidemiology ; Hypothyroidism/metabolism ; Male ; Osteoporosis/prevention & control ; Switzerland/epidemiology ; Thyroxine/pharmacology
Czasopismo naukowe
Tytuł :
Homozygous GRN mutations: new phenotypes and new insights into pathological and molecular mechanisms.
Autorzy :
Huin V; Sorbonne Université, Institut du Cerveau et de la Moelle épinière (ICM), AP-HP, INSERM, CNRS, University Hospital Pitié-Salpêtrière, Paris, France.
Barbier M; Sorbonne Université, Institut du Cerveau et de la Moelle épinière (ICM), AP-HP, INSERM, CNRS, University Hospital Pitié-Salpêtrière, Paris, France.
Bottani A; Department of Genetic Medicine, University Hospital of Geneva, Geneva, Switzerland.
Lobrinus JA; Neuropathology Unit, University Hospital of Geneva, Geneva, Switzerland.
Clot F; Department of Molecular and Cellular Neurogenetics, AP-HP, Pitié-Salpêtrière - Charles Foix University Hospitals, Paris, France.
Lamari F; AP-HP, Metabolic Biochemistry Unit, Department of Biochemistry of Neurometabolic Diseases, Pitié-Salpêtrière University Hospital, Paris, France.
Chat L; Department of Molecular and Cellular Neurogenetics, AP-HP, Pitié-Salpêtrière - Charles Foix University Hospitals, Paris, France.
Rucheton B; AP-HP, Metabolic Biochemistry Unit, Department of Biochemistry of Neurometabolic Diseases, Pitié-Salpêtrière University Hospital, Paris, France.
Fluchère F; AP-HM, Department of Neurology and Movement Disorders, La Timone, Clinical Neuroscience Unit, Aix-Marseille University, France.
Auvin S; AP-HP Department of Pediatric Neurology, Robert Debré University Hospital, F, Paris, France.
Myers P; Medical Office, Geneva, Switzerland.
Gelot A; Neuropathology, Department of Pathology, Trusseau Hospital, AP-HP, Paris, France and INMED INSERM U901 Luminy Campus, Aix-Marseille University, France.
Camuzat A; Sorbonne Université, Institut du Cerveau et de la Moelle épinière (ICM), AP-HP, INSERM, CNRS, University Hospital Pitié-Salpêtrière, Paris, France.
Caillaud C; Biochemical, Metabolomical and Proteonomical Department, Necker-Enfants Malades University Hospital, AP-HP, F-75015 Paris, France.
Jornéa L; Sorbonne Université, Institut du Cerveau et de la Moelle épinière (ICM), AP-HP, INSERM, CNRS, University Hospital Pitié-Salpêtrière, Paris, France.
Forlani S; Sorbonne Université, Institut du Cerveau et de la Moelle épinière (ICM), AP-HP, INSERM, CNRS, University Hospital Pitié-Salpêtrière, Paris, France.
Saracino D; Sorbonne Université, Institut du Cerveau et de la Moelle épinière (ICM), AP-HP, INSERM, CNRS, University Hospital Pitié-Salpêtrière, Paris, France.
Duyckaerts C; Department of Neuropathology 'Escourolle', AP-HP, Pitié-Salpêtrière University Hospital, Paris, France.
Brice A; Sorbonne Université, Institut du Cerveau et de la Moelle épinière (ICM), AP-HP, INSERM, CNRS, University Hospital Pitié-Salpêtrière, Paris, France.; AP-HP, National Reference Center for Rare Diseases 'Neurogenetics', Pitié-Salpêtrière University Hospital, Paris, France.
Durr A; Sorbonne Université, Institut du Cerveau et de la Moelle épinière (ICM), AP-HP, INSERM, CNRS, University Hospital Pitié-Salpêtrière, Paris, France.; AP-HP, National Reference Center for Rare Diseases 'Neurogenetics', Pitié-Salpêtrière University Hospital, Paris, France.
Le Ber I; Sorbonne Université, Institut du Cerveau et de la Moelle épinière (ICM), AP-HP, INSERM, CNRS, University Hospital Pitié-Salpêtrière, Paris, France.; AP-HP, National Reference center 'rare and young dementias', IM2A, Pitié-Salpêtrière University Hospital, Paris, France.
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Źródło :
Brain : a journal of neurology [Brain] 2020 Jan 01; Vol. 143 (1), pp. 303-319.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Frontotemporal Dementia/*genetics
Neuronal Ceroid-Lipofuscinoses/*genetics
Parkinsonian Disorders/*genetics
Progranulins/*genetics
Adolescent ; Adult ; Age of Onset ; Cerebellar Ataxia/genetics ; Child ; Cognitive Dysfunction/genetics ; Epilepsy/genetics ; Female ; Frontotemporal Dementia/diagnostic imaging ; Frontotemporal Dementia/physiopathology ; Heterozygote ; Homozygote ; Humans ; Male ; Middle Aged ; Mutation ; Neuronal Ceroid-Lipofuscinoses/diagnostic imaging ; Neuronal Ceroid-Lipofuscinoses/physiopathology ; Parkinsonian Disorders/diagnostic imaging ; Parkinsonian Disorders/physiopathology ; Progranulins/metabolism ; RNA Splicing/genetics ; Rare Diseases ; Retinitis Pigmentosa/genetics ; TDP-43 Proteinopathies/diagnostic imaging ; TDP-43 Proteinopathies/genetics ; TDP-43 Proteinopathies/physiopathology ; Young Adult
Czasopismo naukowe
Tytuł :
Circulating IGF-1 Independently Predicts Blood Pressure in Children With Higher Calcium-Phosphorus Product Levels.
Autorzy :
Xargay-Torrent S; Pediatric Endocrinology Research Group, (Girona Biomedical Research Institute) IDIBGI, Salt, Spain.
Dorado-Ceballos E; Department of Pediatrics, Dr. Trueta University Hospital, Girona, Spain.
Benavides-Boixader A; Pediatric Endocrinology Research Group, (Girona Biomedical Research Institute) IDIBGI, Salt, Spain.
Lizárraga-Mollinedo E; Pediatric Endocrinology Research Group, (Girona Biomedical Research Institute) IDIBGI, Salt, Spain.
Mas-Parés B; Materno-Fetal Metabolic Research Group, (Girona Biomedical Research Institute) IDIBGI, Salt, Spain.
Montesinos-Costa M; Clinical Laboratory, Dr. Josep Trueta Hospital, Girona, Spain.
De Zegher F; Department of Development & Regeneration, University of Leuven, Leuven, Belgium.
Ibáñez L; Pediatric Endocrinology, Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), ISCIII, Madrid, Spain.
Bassols J; Materno-Fetal Metabolic Research Group, (Girona Biomedical Research Institute) IDIBGI, Salt, Spain.
López-Bermejo A; Pediatric Endocrinology Research Group, (Girona Biomedical Research Institute) IDIBGI, Salt, Spain.; Department of Pediatrics, Dr. Trueta University Hospital, Girona, Spain.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2020 Jan 01; Vol. 105 (1).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Pressure*/physiology
Calcium/*blood
Hypertension/*diagnosis
Insulin-Like Growth Factor I/*metabolism
Phosphorus/*blood
Adolescent ; Age of Onset ; Biomarkers/analysis ; Biomarkers/blood ; Calcium/metabolism ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Child ; Child, Preschool ; Cohort Studies ; Female ; Humans ; Hypertension/blood ; Hypertension/epidemiology ; Insulin-Like Growth Factor I/analysis ; Longitudinal Studies ; Male ; Phosphorus/metabolism ; Prognosis ; Risk Factors ; Spain/epidemiology
Czasopismo naukowe
Tytuł :
Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia.
Autorzy :
Blauwendraat C; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Reed X; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Krohn L; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Heilbron K; 23andMe, Inc., Mountain View, CA, USA.
Bandres-Ciga S; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Tan M; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.
Gibbs JR; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Hernandez DG; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Kumaran R; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Langston R; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Bonet-Ponce L; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Alcalay RN; Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA.
Hassin-Baer S; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Department of Neurology, Sheba Medical Center, Tel Hashomer, Israel.; Movement Disorders Institute, Sheba Medical Center, Tel Hashomer, Israel.; The Joseph Sagol Neuroscience Center, Sheba Medical Center, Tel Hashomer, Israel.
Greenbaum L; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; The Joseph Sagol Neuroscience Center, Sheba Medical Center, Tel Hashomer, Israel.; The Danek Gertner Institute of Human Genetics, Sheba Medical Center, Tel Hashomer, Israel.
Iwaki H; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Leonard HL; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Grenn FP; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Ruskey JA; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Sabir M; Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Ahmed S; Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Makarious MB; Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Pihlstrøm L; Department of Neurology, Oslo University Hospital, Oslo, Norway.
Toft M; Department of Neurology, Oslo University Hospital, Oslo, Norway.
van Hilten JJ; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Marinus J; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Schulte C; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany.
Brockmann K; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany.
Sharma M; Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometry, University of Tubingen, Germany.
Siitonen A; Institute of Clinical Medicine, Department of Neurology, University of Oulu, Oulu, Finland.; Department of Neurology and Medical Research Center, Oulu University Hospital, Oulu, Finland.
Majamaa K; Institute of Clinical Medicine, Department of Neurology, University of Oulu, Oulu, Finland.; Department of Neurology and Medical Research Center, Oulu University Hospital, Oulu, Finland.
Eerola-Rautio J; Department of Neurology, Helsinki University Hospital, and Molecular Neurology, Research Programs Unit, Biomedicum, University of Helsinki, Helsinki, Finland.
Tienari PJ; Department of Neurology, Helsinki University Hospital, and Molecular Neurology, Research Programs Unit, Biomedicum, University of Helsinki, Helsinki, Finland.
Pantelyat A; Neuroregeneration and Stem Cell Program, Institute for Cell Engineering, Johns Hopkins University Medical Center, Baltimore, MD, USA.
Hillis AE; Neuroregeneration and Stem Cell Program, Institute for Cell Engineering, Johns Hopkins University Medical Center, Baltimore, MD, USA.
Dawson TM; Neuroregeneration and Stem Cell Program, Institute for Cell Engineering, Johns Hopkins University Medical Center, Baltimore, MD, USA.; Department of Neurology, Johns Hopkins University Medical Center, Baltimore, MD, USA.
Rosenthal LS; Department of Neurology, Johns Hopkins University Medical Center, Baltimore, MD, USA.
Albert MS; Department of Neurology, Johns Hopkins University Medical Center, Baltimore, MD, USA.
Resnick SM; Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, MD, USA.
Ferrucci L; Longitudinal Studies Section, National Institute on Aging, Baltimore, MD, USA.
Morris CM; Newcastle Brain Tissue Resource, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK.
Pletnikova O; Department of Pathology (Neuropathology, Johns Hopkins University Medical Center, Baltimore, MD, USA.
Troncoso J; Department of Neurology, Johns Hopkins University Medical Center, Baltimore, MD, USA.; Department of Pathology (Neuropathology, Johns Hopkins University Medical Center, Baltimore, MD, USA.
Grosset D; Department of Neurology, Institute of Neurological Sciences, Queen Elizabeth University Hospital, Glasgow, UK.
Lesage S; Inserm U1127, Sorbonne Universités, UPMC Univ Paris 06 UMR S1127, Institut du Cerveau et de la Moelle épinière, ICM, Paris, France.
Corvol JC; Inserm U1127, Sorbonne Universités, UPMC Univ Paris 06 UMR S1127, Institut du Cerveau et de la Moelle épinière, ICM, Paris, France.
Brice A; Inserm U1127, Sorbonne Universités, UPMC Univ Paris 06 UMR S1127, Institut du Cerveau et de la Moelle épinière, ICM, Paris, France.
Noyce AJ; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.; Preventive Neurology Unit, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK.
Masliah E; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Wood N; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.
Hardy J; Department of Neurodegenerative Diseases, UCL Queen Square Institute of Neurology, London, UK.
Shulman LM; Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA.
Jankovic J; Department of Neurology, Baylor College of Medicine, Houston, USA.
Shulman JM; Department of Neurology, Baylor College of Medicine, Houston, USA.; Departments of Molecular and Human Genetics and Neuroscience, Baylor College of Medicine, Houston, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, USA.
Heutink P; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany.
Gasser T; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany.
Cannon P; 23andMe, Inc., Mountain View, CA, USA.
Scholz SW; Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.; Department of Neurology, Johns Hopkins University Medical Center, Baltimore, MD, USA.
Morris H; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.
Cookson MR; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA.
Gan-Or Z; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.
Singleton AB; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
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Corporate Authors :
23andMe Research Team
Źródło :
Brain : a journal of neurology [Brain] 2020 Jan 01; Vol. 143 (1), pp. 234-248.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Penetrance*
Cathepsin B/*genetics
Glucosylceramidase/*genetics
Lewy Body Disease/*genetics
Parkinson Disease/*genetics
alpha-Synuclein/*genetics
Age of Onset ; Case-Control Studies ; Cathepsin B/metabolism ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Genotype ; Glucosylceramidase/metabolism ; Humans ; Induced Pluripotent Stem Cells ; Lewy Body Disease/metabolism ; Neurogenesis/genetics ; Neurons/metabolism ; Parkinson Disease/metabolism ; Polymorphism, Single Nucleotide ; RNA, Messenger/metabolism ; Risk Factors ; Whole Genome Sequencing ; alpha-Synuclein/metabolism
Czasopismo naukowe

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