Autor: "Ahmed, R." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Dynamics and turnover of memory CD8 T cell responses following yellow fever vaccination.
Autorzy:: Zarnitsyna VI; Department of Microbiology and Immunology, Emory University, Atlanta, Georgia, United States of America.
Akondy RS; Department of Microbiology and Immunology, Emory University, Atlanta, Georgia, United States of America.; Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.; Trivedi School of Biosciences, Ashoka University, Sonipat, Haryana, India.
Ahmed H; Department of Biology, Emory University, Atlanta, Georgia, United States of America.
McGuire DJ; Department of Microbiology and Immunology, Emory University, Atlanta, Georgia, United States of America.
Zarnitsyn VG; Moonlight Therapeutics Inc., Atlanta, Georgia, United States of America.
Moore M; Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Johnson PLF; Department of Biology, University of Maryland, College Park, Maryland, United States of America.
Ahmed R; Department of Microbiology and Immunology, Emory University, Atlanta, Georgia, United States of America.; Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Li KW; Department of Nutritional Sciences and Toxicology, UC Berkeley, Berkeley, California, United States of America.
Hellerstein MK; Department of Nutritional Sciences and Toxicology, UC Berkeley, Berkeley, California, United States of America.
Antia R; Department of Biology, Emory University, Atlanta, Georgia, United States of America.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2021 Oct 14; Vol. 17 (10), pp. e1009468. Date of Electronic Publication: 2021 Oct 14 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: CD8-Positive T-Lymphocytes/*immunology
Immunologic Memory/*immunology
Yellow Fever Vaccine/*immunology
Yellow fever virus/*immunology
Computational Biology ; Humans ; Models, Immunological

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Skocz do pozycji: 2.

Tytuł:: Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.
Autorzy:: Kamphorst AO; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Wieland A; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Nasti T; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Yang S; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Xiangya School of Medicine, Central South University, Changsha, Hunan Province, China, 410013.
Zhang R; Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02144, USA.
Barber DL; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Konieczny BT; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Daugherty CZ; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Koenig L; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.
Yu K; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.
Sica GL; Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Sharpe AH; Department of Microbiology and Immunobiology and Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Woman's Hospital, Boston, MA 02115, USA.
Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Blazar BR; Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN 55455, USA.
Turka LA; Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02144, USA.
Owonikoko TK; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.
Pillai RN; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.
Ramalingam SS; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.
Araki K; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Ahmed R; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA. .; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2017 Mar 31; Vol. 355 (6332), pp. 1423-1427. Date of Electronic Publication: 2017 Mar 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: B7-1 Antigen/*metabolism
CD28 Antigens/*metabolism
CD8-Positive T-Lymphocytes/*immunology
Carcinoma, Non-Small-Cell Lung/*therapy
Lung Neoplasms/*therapy
Lymphocytic Choriomeningitis/*therapy
Programmed Cell Death 1 Receptor/*antagonists & inhibitors
Animals ; B7-1 Antigen/genetics ; CD28 Antigens/genetics ; Gene Deletion ; Humans ; Immunotherapy ; Metabolic Networks and Pathways ; Mice

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Skocz do pozycji: 3.

Tytuł:: Autophagy is essential for effector CD8(+) T cell survival and memory formation.
Autorzy:: Xu X; Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.
Araki K; Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.
Li S; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Han JH; Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.
Ye L; Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.
Tan WG; Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.
Konieczny BT; Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.
Bruinsma MW; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Martinez J; Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Pearce EL; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Green DR; Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Jones DP; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Virgin HW; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Ahmed R; Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.; Pokaż więcej
Źródło:: Nature immunology [Nat Immunol] 2014 Dec; Vol. 15 (12), pp. 1152-61. Date of Electronic Publication: 2014 Nov 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Autophagy/*immunology
CD8-Positive T-Lymphocytes/*immunology
Cell Differentiation/*immunology
Immunologic Memory/*immunology
Animals ; Cell Separation ; Cell Survival/immunology ; Chromatography, Liquid ; Flow Cytometry ; Immunoblotting ; Lymphocyte Activation/immunology ; Lymphocytic Choriomeningitis/immunology ; Mass Spectrometry ; Mice ; Mice, Mutant Strains ; Oligonucleotide Array Sequence Analysis ; Real-Time Polymerase Chain Reaction ; Transduction, Genetic

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Skocz do pozycji: 4.

Tytuł:: Broadly reactive human CD8 T cells that recognize an epitope conserved between VZV, HSV and EBV.
Autorzy:: Chiu C; Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America; Centre for Respiratory Infection, National Heart and Lung Institute, Imperial College London, London, United Kingdom.
McCausland M; Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Sidney J; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America.
Duh FM; Cancer and Inflammation Program, Laboratory for Experimental Immunology, SAIC Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Rouphael N; Hope Clinic of the Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Division of Infectious Diseases School of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Mehta A; Division of Infectious Diseases School of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Mulligan M; Hope Clinic of the Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Division of Infectious Diseases School of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Carrington M; Cancer and Inflammation Program, Laboratory for Experimental Immunology, SAIC Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
Wieland A; Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Sullivan NL; Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Weinberg A; Departments of Pediatrics, Medicine and Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.
Levin MJ; Departments of Pediatrics, Medicine and Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.
Pulendran B; Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Peters B; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America.
Sette A; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America.
Ahmed R; Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2014 Mar 27; Vol. 10 (3), pp. e1004008. Date of Electronic Publication: 2014 Mar 27 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: CD8-Positive T-Lymphocytes/*immunology
Epitopes, T-Lymphocyte/*immunology
Herpesvirus 3, Human/*immunology
Herpesvirus 4, Human/*immunology
Simplexvirus/*immunology
Adult ; Cross Reactions ; Enzyme-Linked Immunosorbent Assay ; Flow Cytometry ; HLA-A2 Antigen/immunology ; Herpes Zoster Vaccine/immunology ; Humans ; Viral Vaccines/immunology

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Skocz do pozycji: 5.

Tytuł:: T-cell memory differentiation: insights from transcriptional signatures and epigenetics.
Autorzy:: Youngblood B; Emory Vaccine Center, Atlanta, GA, USA.
Hale JS
Ahmed R; Pokaż więcej
Źródło:: Immunology [Immunology] 2013 Jul; Vol. 139 (3), pp. 277-84.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:: Cell Differentiation*/genetics
Cell Differentiation*/immunology
Epigenomics*
CD4-Positive T-Lymphocytes/*cytology
CD8-Positive T-Lymphocytes/*cytology
CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Gene Expression Regulation ; Humans ; Immunologic Memory ; Lymphocyte Activation

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Skocz do pozycji: 6.

Tytuł:: Phenotypic and functional profiling of malaria-induced CD8 and CD4 T cells during blood-stage infection with Plasmodium yoelii.
Autorzy:: Chandele A; Joint ICGEB-Emory Vaccine Center, Aruna Asaf Ali Marg, New Delhi, India.
Mukerjee P
Das G
Ahmed R
Chauhan VS; Pokaż więcej
Źródło:: Immunology [Immunology] 2011 Feb; Vol. 132 (2), pp. 273-86. Date of Electronic Publication: 2010 Oct 29.
Typ publikacji:: Journal Article
MeSH Terms:: Immunologic Memory*
CD4-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*immunology
Erythrocytes/*parasitology
Malaria/*immunology
Plasmodium yoelii/*immunology
Animals ; CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/metabolism ; Lymphocyte Activation/immunology ; Malaria/parasitology ; Mice ; Mice, Inbred C57BL ; Parasitemia/immunology ; Parasitemia/parasitology ; Phenotype

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Skocz do pozycji: 7.

Tytuł:: The role of mTOR in memory CD8 T-cell differentiation.
Autorzy:: Araki K; Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Youngblood B
Ahmed R; Pokaż więcej
Źródło:: Immunological reviews [Immunol Rev] 2010 May; Vol. 235 (1), pp. 234-43.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Cell Differentiation*/drug effects
Immunologic Memory*/drug effects
CD8-Positive T-Lymphocytes/*immunology
Intracellular Signaling Peptides and Proteins/*immunology
Protein Serine-Threonine Kinases/*immunology
Animals ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/drug effects ; Dendritic Cells/immunology ; Humans ; Immunologic Factors/pharmacology ; Intracellular Signaling Peptides and Proteins/antagonists & inhibitors ; Organ Transplantation ; Protein Serine-Threonine Kinases/antagonists & inhibitors ; Signal Transduction ; Sirolimus/pharmacology ; TOR Serine-Threonine Kinases ; Vaccines/immunology ; Virus Diseases/immunology

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Skocz do pozycji: 8.

Tytuł:: mTOR regulates memory CD8 T-cell differentiation.
Autorzy:: Araki K; Emory Vaccine Center and Department of Microbiology and Immunology, Atlanta, Georgia, USA.
Turner AP
Shaffer VO
Gangappa S
Keller SA
Bachmann MF
Larsen CP
Ahmed R; Pokaż więcej
Źródło:: Nature [Nature] 2009 Jul 02; Vol. 460 (7251), pp. 108-12. Date of Electronic Publication: 2009 Jun 21.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Cell Differentiation*
CD8-Positive T-Lymphocytes/*cytology
CD8-Positive T-Lymphocytes/*immunology
Immunologic Memory/*immunology
Protein Kinases/*metabolism
Animals ; Antigens, Viral/immunology ; Cells, Cultured ; Immunologic Memory/drug effects ; Lymphocyte Count ; Lymphocytic choriomeningitis virus/immunology ; Macaca mulatta/immunology ; Mechanistic Target of Rapamycin Complex 1 ; Mice ; Mice, Inbred C57BL ; Multiprotein Complexes ; Proteins ; Sirolimus/pharmacology ; TOR Serine-Threonine Kinases ; Transcription Factors/metabolism

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Skocz do pozycji: 9.

Tytuł:: Memory CD8 T-cell compartment grows in size with immunological experience.
Autorzy:: Vezys V; Department of Microbiology and Center for Immunology, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Yates A
Casey KA
Lanier G
Ahmed R
Antia R
Masopust D; Pokaż więcej
Źródło:: Nature [Nature] 2009 Jan 08; Vol. 457 (7226), pp. 196-9. Date of Electronic Publication: 2008 Nov 12.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Lymphocyte Count*
CD8-Positive T-Lymphocytes/*cytology
CD8-Positive T-Lymphocytes/*immunology
Immunologic Memory/*immunology
Animals ; B-Lymphocytes/cytology ; CD4-Positive T-Lymphocytes/cytology ; Cells, Cultured ; Hyaluronan Receptors/metabolism ; Immunodominant Epitopes/immunology ; L-Selectin/metabolism ; Lymphocytic choriomeningitis virus/immunology ; Mice ; Mice, Inbred C57BL ; Vaccination ; Viral Vaccines/administration & dosage ; Viral Vaccines/immunology

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Skocz do pozycji: 10.

Tytuł:: Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections.
Autorzy:: Ha SJ; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
West EE
Araki K
Smith KA
Ahmed R; Pokaż więcej
Źródło:: Immunological reviews [Immunol Rev] 2008 Jun; Vol. 223, pp. 317-33.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Immunotherapy, Active*
CD8-Positive T-Lymphocytes/*virology
Viral Vaccines/*pharmacology
Virus Diseases/*immunology
Virus Diseases/*therapy
Animals ; Antigens, Viral/immunology ; Antiviral Agents/pharmacology ; CD8-Positive T-Lymphocytes/immunology ; Chronic Disease ; Cytotoxicity, Immunologic ; Drug Resistance, Viral ; Epitopes, T-Lymphocyte/immunology ; Humans ; Lymphocyte Activation

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Skocz do pozycji: 11.

Tytuł:: PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.
Autorzy:: Day CL; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu Natal, Durban 4013, South Africa.
Kaufmann DE
Kiepiela P
Brown JA
Moodley ES
Reddy S
Mackey EW
Miller JD
Leslie AJ
DePierres C
Mncube Z
Duraiswamy J
Zhu B
Eichbaum Q
Altfeld M
Wherry EJ
Coovadia HM
Goulder PJ
Klenerman P
Ahmed R
Freeman GJ
Walker BD; Pokaż więcej
Źródło:: Nature [Nature] 2006 Sep 21; Vol. 443 (7109), pp. 350-4. Date of Electronic Publication: 2006 Aug 20.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Antigens, CD/*metabolism
Apoptosis Regulatory Proteins/*metabolism
CD8-Positive T-Lymphocytes/*pathology
CD8-Positive T-Lymphocytes/*virology
HIV/*physiology
HIV Infections/*metabolism
HIV Infections/*pathology
Apoptosis Regulatory Proteins/antagonists & inhibitors ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Disease Progression ; Gene Expression ; HIV Infections/immunology ; HIV Infections/virology ; Histocompatibility Antigens Class I/immunology ; Histocompatibility Antigens Class I/metabolism ; Humans ; Interferon-gamma/immunology ; Interferon-gamma/metabolism ; Programmed Cell Death 1 Receptor ; Up-Regulation

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Skocz do pozycji: 12.

Tytuł:: How does cross-reactive stimulation affect the longevity of CD8+ T cell memory?
Autorzy:: Ganusov VV; Department of Biology, Emory University, Atlanta, Georgia, USA.
Pilyugin SS
Ahmed R
Antia R; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2006 Jun 09; Vol. 2 (6), pp. e55. Date of Electronic Publication: 2006 Jun 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: CD8-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*physiology
Animals ; Cell Lineage ; Immunologic Memory ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Models, Immunological ; Models, Statistical ; Models, Theoretical ; Vertebrates

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Skocz do pozycji: 13.

Tytuł:: Restoring function in exhausted CD8 T cells during chronic viral infection.
Autorzy:: Barber DL; Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Wherry EJ
Masopust D
Zhu B
Allison JP
Sharpe AH
Freeman GJ
Ahmed R; Pokaż więcej
Źródło:: Nature [Nature] 2006 Feb 09; Vol. 439 (7077), pp. 682-7. Date of Electronic Publication: 2005 Dec 28.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: CD8-Positive T-Lymphocytes/*immunology
Virus Diseases/*immunology
Animals ; Antigens, CD ; Antigens, Differentiation/immunology ; Antigens, Surface/genetics ; Antigens, Surface/metabolism ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; B7-1 Antigen/genetics ; B7-1 Antigen/metabolism ; B7-H1 Antigen ; CD8-Positive T-Lymphocytes/cytology ; CTLA-4 Antigen ; Cell Proliferation ; Chronic Disease ; Gene Expression Regulation ; Immune Tolerance/immunology ; Lymphocytic Choriomeningitis/immunology ; Lymphocytic choriomeningitis virus/immunology ; Lymphocytic choriomeningitis virus/physiology ; Membrane Glycoproteins/deficiency ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/metabolism ; Mice ; Peptides/deficiency ; Peptides/genetics ; Peptides/metabolism ; Programmed Cell Death 1 Receptor ; Substrate Specificity

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Skocz do pozycji: 14.

Tytuł:: Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin.
Autorzy:: Intlekofer AM; Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Takemoto N
Wherry EJ
Longworth SA
Northrup JT
Palanivel VR
Mullen AC
Gasink CR
Kaech SM
Miller JD
Gapin L
Ryan K
Russ AP
Lindsten T
Orange JS
Goldrath AW
Ahmed R
Reiner SL; Pokaż więcej
Źródło:: Nature immunology [Nat Immunol] 2005 Dec; Vol. 6 (12), pp. 1236-44. Date of Electronic Publication: 2005 Nov 06.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: CD8-Positive T-Lymphocytes/*physiology
Immunologic Memory/*physiology
T-Box Domain Proteins/*physiology
Transcription Factors/*physiology
Animals ; Cells, Cultured ; Humans ; Interleukin-15/deficiency ; Interleukin-15/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Phenotype ; Receptors, Interleukin-2/metabolism ; T-Box Domain Proteins/biosynthesis ; T-Box Domain Proteins/genetics ; T-Box Domain Proteins/metabolism

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Skocz do pozycji: 15.

Tytuł:: The role of models in understanding CD8+ T-cell memory.
Autorzy:: Antia R; Department of Biology, Emory University, Atlanta, Georgia 30322, USA. />Ganusov VV
Ahmed R; Pokaż więcej
Źródło:: Nature reviews. Immunology [Nat Rev Immunol] 2005 Feb; Vol. 5 (2), pp. 101-11.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review
MeSH Terms:: Immunologic Memory*
Models, Immunological*
CD8-Positive T-Lymphocytes/*immunology
Animals ; Cell Differentiation/immunology ; Humans

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Skocz do pozycji: 16.

Tytuł:: Antigen-specific beta-chemokine production and CD8 T-cell noncytotoxic antiviral activity in HIV-2-infected individuals.
Autorzy:: Ahmed RK; Tumorbiology Center, Karolinska Institute, Solna, Sweden. raija.ahmed@smi.ki.se
Norrgren H
da Silva Z
Blaxhult A
Fredriksson EL
Biberfeld G
Andersson S
Thorstensson R; Pokaż więcej
Źródło:: Scandinavian journal of immunology [Scand J Immunol] 2005 Jan; Vol. 61 (1), pp. 63-71.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: CD8-Positive T-Lymphocytes/*immunology
Chemokines, CC/*biosynthesis
HIV Infections/*immunology
HIV-2/*immunology
Adult ; Chemokine CCL4 ; Chemokine CCL5/biosynthesis ; Female ; Guinea-Bissau ; HIV Antigens ; HIV Infections/virology ; HIV-1/immunology ; HIV-1/pathogenicity ; HIV-1/physiology ; HIV-2/pathogenicity ; HIV-2/physiology ; Humans ; In Vitro Techniques ; Macrophage Inflammatory Proteins/biosynthesis ; Male ; Middle Aged ; Sweden ; Virus Replication

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Skocz do pozycji: 17.

Tytuł:: Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.
Autorzy:: Kaech SM; Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, 1510 Clifton Road, Atlanta, Georgia 30322, USA.
Tan JT
Wherry EJ
Konieczny BT
Surh CD
Ahmed R; Pokaż więcej
Źródło:: Nature immunology [Nat Immunol] 2003 Dec; Vol. 4 (12), pp. 1191-8. Date of Electronic Publication: 2003 Nov 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Immunologic Memory*
CD8-Positive T-Lymphocytes/*cytology
Cell Differentiation/*immunology
Receptors, Interleukin-7/*biosynthesis
T-Lymphocyte Subsets/*cytology
Adoptive Transfer ; Animals ; Antigens, Surface ; CD8-Positive T-Lymphocytes/physiology ; Cell Lineage/immunology ; Gene Expression/immunology ; Lymphocyte Activation ; Lymphocytic Choriomeningitis/immunology ; Lymphocytic choriomeningitis virus/immunology ; Mice ; Mice, Transgenic ; Oligonucleotide Array Sequence Analysis ; Signal Transduction/immunology ; T-Lymphocyte Subsets/physiology

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Skocz do pozycji: 18.

Tytuł:: Immunology. CD8 T cells remember with a little help.
Autorzy:: Kaech SM; Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA.
Ahmed R; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2003 Apr 11; Vol. 300 (5617), pp. 263-5.
Typ publikacji:: Journal Article; Comment
MeSH Terms:: Immunologic Memory*
CD8-Positive T-Lymphocytes/*immunology
T-Lymphocytes, Helper-Inducer/*immunology
Animals ; Antigen-Presenting Cells/immunology ; B-Lymphocytes/immunology ; Bacterial Infections/immunology ; CD40 Antigens/metabolism ; CD8-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/physiology ; Cell Differentiation ; Cell Division ; Gene Expression ; Homeostasis ; Interferon-gamma/biosynthesis ; Interferon-gamma/immunology ; Interleukin-2/biosynthesis ; Interleukin-2/immunology ; Lymphocyte Activation ; Mice ; Models, Immunological ; T-Lymphocyte Subsets/immunology ; Virus Diseases/immunology

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Skocz do pozycji: 19.

Tytuł:: Lineage relationship and protective immunity of memory CD8 T cell subsets.
Autorzy:: Wherry EJ; Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Teichgräber V
Becker TC
Masopust D
Kaech SM
Antia R
von Andrian UH
Ahmed R; Pokaż więcej
Źródło:: Nature immunology [Nat Immunol] 2003 Mar; Vol. 4 (3), pp. 225-34. Date of Electronic Publication: 2003 Feb 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: CD8-Positive T-Lymphocytes/*immunology
Immunologic Memory/*immunology
Animals ; Cell Communication/immunology ; Cell Division/immunology ; Cell Lineage/immunology ; Listeria monocytogenes/immunology ; Listeriosis/immunology ; Lymphocytic Choriomeningitis/immunology ; Lymphocytic choriomeningitis virus/immunology ; Mice ; Mice, Transgenic

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Skocz do pozycji: 20.

Tytuł:: Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells.
Autorzy:: Kaech SM; Emory Vaccine Center, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA.
Ahmed R; Pokaż więcej
Źródło:: Nature immunology [Nat Immunol] 2001 May; Vol. 2 (5), pp. 415-22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Immunologic Memory*
CD8-Positive T-Lymphocytes/*immunology
Adoptive Transfer ; Animals ; CD8-Positive T-Lymphocytes/cytology ; Cell Differentiation ; Cell Division ; H-2 Antigens/genetics ; Interleukin-2/immunology ; Lymphocyte Activation ; Mice ; Mice, Transgenic ; Models, Immunological ; Thy-1 Antigens/genetics

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