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Wyszukujesz frazę ""Akashi K"" wg kryterium: Autor


Tytuł :
Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.
Autorzy :
Yamauchi T; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan; Department of Stem Cell Biology and Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan.
Masuda T; Department of Pharmaceutical Microbiology, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.
Canver MC; Division of Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
Seiler M; H3 Biomedicine, Inc., Cambridge, MA 02139, USA.
Semba Y; Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan.
Shboul M; Institute of Medical Biology, A∗STAR, 8A Biomedical Grove, Singapore 138648, Singapore.
Al-Raqad M; Institute of Medical Biology, A∗STAR, 8A Biomedical Grove, Singapore 138648, Singapore; Al-Balqa Applied University, Faculty of Science, Al-Salt, Salt 19117, Jordan.
Maeda M; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Schoonenberg VAC; Division of Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
Cole MA; Division of Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
Macias-Trevino C; Division of Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
Ishikawa Y; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Yao Q; Department of Pathology & Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Nakano M; Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan.
Arai F; Department of Stem Cell Biology and Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan.
Orkin SH; Division of Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
Reversade B; Institute of Medical Biology, A∗STAR, 8A Biomedical Grove, Singapore 138648, Singapore.
Buonamici S; H3 Biomedicine, Inc., Cambridge, MA 02139, USA.
Pinello L; Department of Pathology & Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Akashi K; Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan; Center for Cellular and Molecular Medicine, Kyushu University Hospital, Fukuoka 812-8582, Japan.
Bauer DE; Division of Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
Maeda T; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Center for Cellular and Molecular Medicine, Kyushu University Hospital, Fukuoka 812-8582, Japan. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2018 Mar 12; Vol. 33 (3), pp. 386-400.e5. Date of Electronic Publication: 2018 Feb 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
CRISPR-Cas Systems/*drug effects
Endoribonucleases/*drug effects
Leukemia/*drug therapy
Muscular Atrophy, Spinal/*drug therapy
Quinazolines/*pharmacology
Animals ; CRISPR-Cas Systems/genetics ; Cell Line ; Endoribonucleases/genetics ; Endoribonucleases/metabolism ; Humans ; Leukemia/genetics ; Male ; Metabolic Networks and Pathways/drug effects ; Mice, Inbred C57BL ; Muscular Atrophy, Spinal/genetics ; RNA Precursors/drug effects ; RNA Precursors/genetics ; RNA Splicing/drug effects ; RNA Splicing/genetics ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł :
Progress in the leukemic stem cell study and a novel therapeutic approach targeting leukemic stem cells.
Autorzy :
Kikushige Y; Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Science.
Miyamoto T; Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Science.
Akashi K; Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Science.
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Źródło :
[Rinsho ketsueki] The Japanese journal of clinical hematology [Rinsho Ketsueki] 2017; Vol. 58 (10), pp. 1838-1843.
Typ publikacji :
Journal Article
MeSH Terms :
Hematopoietic Stem Cells*
Leukemia*/diagnosis
Neoplastic Stem Cells*
Animals ; Humans ; Prognosis
Czasopismo naukowe
Tytuł :
Nuclear export signal within CALM is necessary for CALM-AF10-induced leukemia.
Autorzy :
Suzuki M; Division of Hematological Malignancy, National Cancer Center Research Institute, Tokyo, Japan.
Yamagata K
Shino M
Aikawa Y
Akashi K
Watanabe T
Kitabayashi I
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Źródło :
Cancer science [Cancer Sci] 2014 Mar; Vol. 105 (3), pp. 315-23. Date of Electronic Publication: 2014 Feb 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Leukemia/*metabolism
Monomeric Clathrin Assembly Proteins/*physiology
Oncogene Proteins, Fusion/*physiology
Transcription Factors/*physiology
Amino Acid Sequence ; Animals ; COS Cells ; Carcinogenesis/genetics ; Carcinogenesis/metabolism ; Chlorocebus aethiops ; Female ; Leukemia/genetics ; Leukemia/pathology ; Mice ; Mice, Inbred C57BL ; Molecular Sequence Data ; Monomeric Clathrin Assembly Proteins/chemistry ; Neoplasm Transplantation ; Nuclear Export Signals ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Guest editorial: leukemia stem cell.
Autorzy :
Akashi K; Department of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan, akashi@med.kyushu-u.ac.jp.
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Źródło :
International journal of hematology [Int J Hematol] 2013 Dec; Vol. 98 (6), pp. 625-6. Date of Electronic Publication: 2013 Nov 12.
Typ publikacji :
Editorial; Introductory Journal Article
MeSH Terms :
Leukemia/*metabolism
Leukemia/*therapy
Neoplastic Stem Cells/*metabolism
Humans
Czasopismo naukowe
Tytuł :
[110th Scientific Meeting of the Japanese Society of Internal Medicine: Symposium: 2. Diseases originated from stem cell abnormalities; 2) Human leukemic stem cell].
Autorzy :
Akashi K; Department of Medicine and Systemic Sciences, Kyushu University, Japan.
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Źródło :
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine [Nihon Naika Gakkai Zasshi] 2013 Sep 10; Vol. 102 (9), pp. 2262-6.
Typ publikacji :
Journal Article
MeSH Terms :
Leukemia/*pathology
Neoplastic Stem Cells/*drug effects
Animals ; Cytological Techniques ; Humans ; Mice ; Neoplastic Stem Cells/pathology
Czasopismo naukowe
Tytuł :
Fatal candidemia caused by azole-resistant Candida tropicalis in patients with hematological malignancies.
Autorzy :
Chong Y; Department of Blood and Marrow Transplantation, Hara-Sanshin Hospital, 1-8 Taihaku-cho, Hakata-ku, Fukuoka, 812-0033, Japan. />Shimoda S
Yakushiji H
Ito Y
Miyamoto T
Shimono N
Kamimura T
Akashi K
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Źródło :
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy [J Infect Chemother] 2012 Oct; Vol. 18 (5), pp. 741-6. Date of Electronic Publication: 2012 Apr 18.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Antifungal Agents/*pharmacology
Azoles/*pharmacology
Candida tropicalis/*isolation & purification
Candidemia/*blood
Candidemia/*microbiology
Leukemia/*microbiology
Aged ; Aged, 80 and over ; Antifungal Agents/therapeutic use ; Azoles/therapeutic use ; Candida tropicalis/drug effects ; Candidemia/drug therapy ; Drug Resistance, Fungal ; Fatal Outcome ; Female ; Humans ; Leukemia/blood ; Lymphoma/blood ; Lymphoma/microbiology ; Male ; Microbial Sensitivity Tests ; Middle Aged
Czasopismo naukowe
Tytuł :
[Leukemia stem cells: current understanding and future directions].
Autorzy :
Takenaka K; Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Science.
Akashi K
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Źródło :
Nihon rinsho. Japanese journal of clinical medicine [Nihon Rinsho] 2012 Apr; Vol. 70 Suppl 2, pp. 139-45.
Typ publikacji :
Journal Article
MeSH Terms :
Leukemia/*pathology
Animals ; Humans ; Leukemia/therapy ; Leukemia, Myeloid, Acute/pathology ; Mice ; Neoplastic Stem Cells ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology
Czasopismo naukowe
Tytuł :
Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.
Autorzy :
Mohi MG; Cancer Biology Program, Department of Medicine, Beth Israel Deaconess Medical Center, 77 Avenue Louis Pasteur, NRB-1030, Boston, Massachusetts 02115, USA. />Williams IR
Dearolf CR
Chan G
Kutok JL
Cohen S
Morgan K
Boulton C
Shigematsu H
Keilhack H
Akashi K
Gilliland DG
Neel BG
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Źródło :
Cancer cell [Cancer Cell] 2005 Feb; Vol. 7 (2), pp. 179-91.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Mutation*
Leukemia/*genetics
Protein Tyrosine Phosphatases/*genetics
Alleles ; Animals ; Animals, Genetically Modified ; Bone Marrow Cells/cytology ; Cell Proliferation ; DNA, Complementary/metabolism ; Disease Models, Animal ; Drosophila ; Drosophila melanogaster ; Flow Cytometry ; Granulocyte-Macrophage Colony-Stimulating Factor/metabolism ; Green Fluorescent Proteins/metabolism ; Immunohistochemistry ; Interleukin-3/metabolism ; Intracellular Signaling Peptides and Proteins ; Leukemia/metabolism ; Mice ; Models, Genetic ; Neoplasms, Experimental ; Protein Structure, Tertiary ; Protein Tyrosine Phosphatase, Non-Receptor Type 11 ; Retroviridae/genetics ; Signal Transduction ; Time Factors
Czasopismo naukowe
Tytuł :
Interferon-gamma prevents apoptosis in Epstein-Barr virus-infected natural killer cell leukemia in an autocrine fashion.
Autorzy :
Mizuno S; First Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Akashi K
Ohshima K
Iwasaki H
Miyamoto T
Uchida N
Shibuya T
Harada M
Kikuchi M
Niho Y
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Źródło :
Blood [Blood] 1999 May 15; Vol. 93 (10), pp. 3494-504.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*immunology
Herpesvirus 4, Human/*isolation & purification
Interferon-gamma/*immunology
Killer Cells, Natural/*immunology
Killer Cells, Natural/*virology
Leukemia/*immunology
Leukemia/*virology
Adolescent ; Adult ; Aged ; Antigens, CD/analysis ; Apoptosis/drug effects ; Cells, Cultured ; Female ; Herpesvirus 4, Human/genetics ; Humans ; Immunophenotyping ; Interferon-gamma/biosynthesis ; Interferon-gamma/pharmacology ; Interleukin-2/biosynthesis ; Killer Cells, Natural/pathology ; Male ; Middle Aged ; Proto-Oncogene Proteins c-bcl-2/biosynthesis ; Tumor Necrosis Factor-alpha/biosynthesis
Czasopismo naukowe
Tytuł :
Evaluation of leukaemic contamination in peripheral blood stem cell harvests by reverse transcriptase polymerase chain reaction.
Autorzy :
Nagafuji K; First Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Harada M
Takamatsu Y
Eto T
Teshima T
Kamura T
Okamura T
Hayashi S
Akashi K
Murakawa M
et. al.
Pokaż więcej
Źródło :
British journal of haematology [Br J Haematol] 1993 Nov; Vol. 85 (3), pp. 578-83.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Transfusion, Autologous*
Hematopoietic Stem Cell Transplantation*
Leukemia/*blood
Neoplastic Stem Cells/*pathology
Adult ; Base Sequence ; Bone Marrow/pathology ; Female ; Humans ; Leukemia/therapy ; Male ; Middle Aged ; Molecular Sequence Data ; Polymerase Chain Reaction ; RNA, Messenger/analysis ; RNA, Neoplasm/analysis ; RNA-Directed DNA Polymerase
Czasopismo naukowe

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