- Tytuł:
-
PU.1 induces
apoptosis in myeloma cells through direct transactivation of TRAIL. - Autorzy:
- Źródło:
- Oncogene [Oncogene] 2009 Nov 19; Vol. 28 (46), pp. 4116-25. Date of Electronic Publication: 2009 Sep 14.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Apoptosis /*genetics
Multiple Myeloma/*pathology
Proto-Oncogene Proteins/*physiology
TNF-RelatedApoptosis -Inducing Ligand/*genetics
Trans-Activators/*physiology
Cell Cycle/drug effects ; Cell Cycle/genetics ; Cell Line, Tumor ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Interferon Regulatory Factor-7/genetics ; Interferon Regulatory Factor-7/metabolism ; Interferon Regulatory Factors/genetics ; Interferon Regulatory Factors/metabolism ; Interferons/pharmacology ; Multiple Myeloma/genetics ; Multiple Myeloma/metabolism ; Promoter Regions, Genetic ; Protein Binding ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Transcriptional Activation/genetics
Czasopismo naukowe