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Tytuł :
Rutin and quercetin show greater efficacy than nifedipin in ameliorating hemodynamic, redox, and metabolite imbalances in sodium chloride-induced hypertensive rats.
Autorzy :
Olaleye, MT
Crown, OO
Akinmoladun, AC
Akindahunsi, AA
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Temat :
RUTIN
QUERCETIN
NIFEDIPINE
CARDIOVASCULAR disease diagnosis
HYPERTENSION
ANTIOXIDANTS
ANTIHYPERTENSIVE agents
Źródło :
Human & Experimental Toxicology; Jun2014, Vol. 33 Issue 6, p602-608, 7p
Czasopismo naukowe
Tytuł :
Network analysis, sequence and structure dynamics of key proteins of coronavirus and human host, and molecular docking of selected phytochemicals of nine medicinal plants.
Autorzy :
Fatoki TH; Translational Bioinformatics Unit, Department of Biochemistry, Federal University Oye Ekiti, Oye Ekiti, Ekiti State, Nigeria.
Ibraheem O; Translational Bioinformatics Unit, Department of Biochemistry, Federal University Oye Ekiti, Oye Ekiti, Ekiti State, Nigeria.
Ogunyemi IO; Department of Nutrition and Biomedicine, Technical University of Munich, Munich, Germany.
Akinmoladun AC; Department of Biochemistry, Federal University of Technology, Akure, Nigeria.
Ugboko HU; Microbiology Research Unit, Department of Biological Sciences, Covenant University, Ota, Ogun State, Nigeria.
Adeseko CJ; Department of Biochemistry, Federal University of Technology, Akure, Nigeria.
Awofisayo OA; Department of Pharmaceutical and Medicinal Chemistry, University of Uyo, Uyo, Nigeria.
Olusegun SJ; Departamento de Quimica, Universidade Federal de Minas Gerias, Belo Horizonte, Brazil.
Enibukun JM; Department of Microbiology, Federal University of Technology, Akure, Nigeria.
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Źródło :
Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2021 Oct; Vol. 39 (16), pp. 6195-6217. Date of Electronic Publication: 2020 Jul 20.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*
Plants, Medicinal*
Humans ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Phytochemicals ; SARS-CoV-2 ; Sequence Analysis
Czasopismo naukowe
Tytuł :
Neuroprotective flavonoids of the leaf of Antiaris africana Englea against cyanide toxicity.
Autorzy :
Ilesanmi OB; Department of Biochemistry, Faculty of Science, The Federal University, Otuoke, Bayelsa State PMB 126, Yenagoa, Bayelsa State, Nigeria. Electronic address: .
Akinmoladun AC; Department of Biochemistry, School of Life Sciences, The Federal University of Technology, PMB 704, Akure, Nigeria.
Elusiyan CA; Faculty of Pharmacy, Obafemi Awolowo University, Ile Ife, Nigeria.
Ogungbe IV; Department of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, USA.
Olugbade TA; Faculty of Pharmacy, Obafemi Awolowo University, Ile Ife, Nigeria.
Olaleye MT; Department of Biochemistry, School of Life Sciences, The Federal University of Technology, PMB 704, Akure, Nigeria.
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2022 Jan 10; Vol. 282, pp. 114592. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Upregulation of PCSK9, rho kinase and cardiac troponin by Eucalyptus globulus leaf extract improves fructose-streptozotocin-induced diabetic cardiac dysfunction in rats.
Autorzy :
Akinmoladun AC; Phytomedicine, Biochemical Pharmacology and Toxicology Research Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Bello M; Phytomedicine, Biochemical Pharmacology and Toxicology Research Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Ibukun EO; Phytomedicine, Biochemical Pharmacology and Toxicology Research Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
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Źródło :
Archives of physiology and biochemistry [Arch Physiol Biochem] 2021 Jul 16, pp. 1-10. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Modifying influence of polyphenols on hematotoxicity, cardiotoxicity, and hepatotoxicity induced by liquefied petroleum gas in rats.
Autorzy :
Akinmoladun AC
Aladesanmi OO; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure 340001, Nigeria.
Ojo FE; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure 340001, Nigeria.
Bello M; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure 340001, Nigeria.
Taiwo BJ; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure 340001, Nigeria.
Akindahunsi AA; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure 340001, Nigeria.
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Źródło :
Toxicology research [Toxicol Res (Camb)] 2021 Jun 26; Vol. 10 (4), pp. 751-760. Date of Electronic Publication: 2021 Jun 26 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Protective properties of Spondias mombin Linn leaves on redox status, cholinergic dysfunction and electrolyte disturbance in cyanide-intoxicated rats.
Autorzy :
Akinmoladun AC; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Adelabu AA; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Saliu IO; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Adetuyi AR; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Olaleye MT; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
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Źródło :
Science progress [Sci Prog] 2021 Apr-Jun; Vol. 104 (2), pp. 368504211011866.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Coronavirus Disease 2019 and Herbal Therapy: Pertinent Issues Relating to Toxicity and Standardization of Phytopharmaceuticals.
Autorzy :
Komolafe K; Department of Biochemistry, Faculty of Science, Federal University Oye-Ekiti, PMB 373, Oye-Ekiti, Nigeria.
Komolafe TR; Department of Biochemistry, Faculty of Science, Federal University Oye-Ekiti, PMB 373, Oye-Ekiti, Nigeria.; Department of Biochemistry, School of Sciences, The Federal University of Technology, PMB 704, Akure, Nigeria.
Fatoki TH; Department of Biochemistry, School of Sciences, The Federal University of Technology, PMB 704, Akure, Nigeria.
Akinmoladun AC; Department of Biochemistry, School of Sciences, The Federal University of Technology, PMB 704, Akure, Nigeria.
Brai BIC; Department of Biochemistry, Faculty of Science, Federal University Oye-Ekiti, PMB 373, Oye-Ekiti, Nigeria.
Olaleye MT; Department of Biochemistry, School of Sciences, The Federal University of Technology, PMB 704, Akure, Nigeria.
Akindahunsi AA; Department of Biochemistry, School of Sciences, The Federal University of Technology, PMB 704, Akure, Nigeria.
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Źródło :
Revista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia [Rev Bras Farmacogn] 2021 Mar 11, pp. 1-20. Date of Electronic Publication: 2021 Mar 11.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Prophylaxis with a multicomponent nutraceutical abates transient cerebral ischemia/reperfusion injury.
Autorzy :
Akinmoladun AC; Department of Biochemistry, The Federal University of Technology, Akure, Nigeria.
Obadaye TS; Department of Biochemistry, The Federal University of Technology, Akure, Nigeria.
Olaleye MT; Department of Biochemistry, The Federal University of Technology, Akure, Nigeria.
Akindahunsi AA; Department of Biochemistry, The Federal University of Technology, Akure, Nigeria.
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Źródło :
Journal of food biochemistry [J Food Biochem] 2021 Mar; Vol. 45 (3), pp. e13351. Date of Electronic Publication: 2020 Jul 02.
Typ publikacji :
Journal Article
MeSH Terms :
Ischemic Attack, Transient*
Reperfusion Injury*/drug therapy
Reperfusion Injury*/prevention & control
Animals ; Dietary Supplements ; Male ; Oxidative Stress ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Toxicological and pharmacological assessment of a multiherbal phytopharmaceutical on Triton X-1339-induced hyperlipidemia and allied biochemical dysfunctions.
Autorzy :
Akinmoladun AC; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, The Federal University of Technology, School of Sciences, Akure, Nigeria.
Adegbamigbe AD; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, The Federal University of Technology, School of Sciences, Akure, Nigeria.
Okafor NR; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, The Federal University of Technology, School of Sciences, Akure, Nigeria.
Josiah SS; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, The Federal University of Technology, School of Sciences, Akure, Nigeria.
Olaleye MT; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, The Federal University of Technology, School of Sciences, Akure, Nigeria.
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Źródło :
Journal of food biochemistry [J Food Biochem] 2021 Mar; Vol. 45 (3), pp. e13238. Date of Electronic Publication: 2020 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
Hyperlipidemias*/chemically induced
Hyperlipidemias*/drug therapy
Animals ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Hypolipidemic Agents/therapeutic use ; Liver ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Reduction of anoxia-induced bioenergetic disturbance in astrocytes by methanol fruit extract of Tetrapleura tetraptera and in silico evaluation of the effect of its antioxidative constituents on excitotoxicity.
Autorzy :
Saliu IO; Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, 340001, Nigeria.; Department of System and Cognitive Neuroscience, National Brain Research Center (NBRC), Manesar, Haryana, 122052, India.
Bhagat R; Neurovirology Section, Department of Molecular and Cellular Neuroscience, National Brain Research Centre (NBRC), Manesar, Haryana, 122052, India.
Ojo OB; Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, 340001, Nigeria.
Akinmoladun AC; Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, 340001, Nigeria.
Olaleye MT; Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, 340001, Nigeria.
Seth P; Neurovirology Section, Department of Molecular and Cellular Neuroscience, National Brain Research Centre (NBRC), Manesar, Haryana, 122052, India.
Rema V; Department of System and Cognitive Neuroscience, National Brain Research Center (NBRC), Manesar, Haryana, 122052, India.
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Źródło :
Toxicology reports [Toxicol Rep] 2021 Jan 26; Vol. 8, pp. 264-276. Date of Electronic Publication: 2021 Jan 26 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Abatement of neurobehavioral and neurochemical dysfunctions in cerebral ischemia/reperfusion injury by Tetrapleura tetraptera fruit extract.
Autorzy :
Saliu IO; Phytomedicine, Biochemical Pharmacology and Toxicology Research Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure 340001, Nigeria; Department of System Neuroscience, National Brain Research Centre, Manesar 122052, Haryana, India.
Amoo ZA; Phytomedicine, Biochemical Pharmacology and Toxicology Research Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure 340001, Nigeria.
Khan MF; Department of Biotechnology, Era's Lucknow Medical College, Era University, Hardoi Road, Lucknow, 226003, UP, India.
Olaleye MT; Phytomedicine, Biochemical Pharmacology and Toxicology Research Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure 340001, Nigeria.
Rema V; Department of System Neuroscience, National Brain Research Centre, Manesar 122052, Haryana, India.
Akinmoladun AC; Phytomedicine, Biochemical Pharmacology and Toxicology Research Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure 340001, Nigeria. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Jan 10; Vol. 264, pp. 113284. Date of Electronic Publication: 2020 Aug 22.
Typ publikacji :
Journal Article
MeSH Terms :
Fruit*
Tetrapleura*
Brain Ischemia/*drug therapy
Open Field Test/*drug effects
Plant Extracts/*therapeutic use
Reperfusion Injury/*drug therapy
Animals ; Brain Ischemia/metabolism ; Brain Ischemia/psychology ; Dose-Response Relationship, Drug ; Male ; Open Field Test/physiology ; Plant Extracts/isolation & purification ; Plant Extracts/pharmacology ; Rats ; Rats, Wistar ; Reperfusion Injury/metabolism ; Reperfusion Injury/psychology ; Water-Electrolyte Balance/drug effects ; Water-Electrolyte Balance/physiology
Czasopismo naukowe
Tytuł :
Modulatory activities of polyphenols on crude acetylene-induced cardiac and hepatic dysfunctions in a rat model.
Autorzy :
Aladesanmi OO; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Akinmoladun AC; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Josiah SS; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Olaleye MT; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Akindahunsi AA; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
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Źródło :
Drug and chemical toxicology [Drug Chem Toxicol] 2020 Dec 08, pp. 1-9. Date of Electronic Publication: 2020 Dec 08.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Kigelia africana (Lam.) Benth leaf extract inhibits rat brain and liver mitochondrial membrane permeability transition pore opening.
Autorzy :
Falode JA; Phytomedicine, Biochemical Pharmacology and Toxicology Unit, Department of Biochemistry, Federal University, Oye-Ekiti, Nigeria.; Phytomedicine, Biochemical Pharmacology and Toxicology Unit, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Akinmoladun AC; Phytomedicine, Biochemical Pharmacology and Toxicology Unit, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Olaleye MT; Phytomedicine, Biochemical Pharmacology and Toxicology Unit, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Akindahunsi AA; Phytomedicine, Biochemical Pharmacology and Toxicology Unit, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
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Źródło :
Drug and chemical toxicology [Drug Chem Toxicol] 2020 Dec 06, pp. 1-11. Date of Electronic Publication: 2020 Dec 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Local Condiment, Iru, Obtained from the Fermentation of Parkia biglobosa Seed Substantially Reduced the Serum Cholesterol Level of Wister Rats.
Autorzy :
Atere AV; Depatrment of Microbiology, Federal University of Technology, Akure, Ondo State 340001, Nigeria.
Adedeji A; Depatrment of Biochemistry, Federal University of Technology, Akure, Ondo State 340001, Nigeria.
Akinmoladun AC; Depatrment of Biochemistry, Federal University of Technology, Akure, Ondo State 340001, Nigeria.
Oyetayo VO; Depatrment of Microbiology, Federal University of Technology, Akure, Ondo State 340001, Nigeria.
Akinyosoye FA; Depatrment of Microbiology, Federal University of Technology, Akure, Ondo State 340001, Nigeria.
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Źródło :
Preventive nutrition and food science [Prev Nutr Food Sci] 2020 Jun 30; Vol. 25 (2), pp. 153-157.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Ameliorative effect of quercetin, catechin, and taxifolin on rotenone-induced testicular and splenic weight gain and oxidative stress in rats.
Autorzy :
Akinmoladun AC; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria, Phone: +234 803 444 5893.
Olaniyan OO; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Famusiwa CD; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Josiah SS; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
Olaleye MT; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology, Akure, Nigeria.
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Źródło :
Journal of basic and clinical physiology and pharmacology [J Basic Clin Physiol Pharmacol] 2020 Jan 15; Vol. 31 (3). Date of Electronic Publication: 2020 Jan 15.
Typ publikacji :
Journal Article
MeSH Terms :
Catechin/*pharmacology
Oxidative Stress/*drug effects
Quercetin/*analogs & derivatives
Quercetin/*pharmacology
Spleen/*physiology
Testis/*physiology
Weight Gain/*drug effects
Animals ; Biomarkers/metabolism ; Dose-Response Relationship, Drug ; Inflammation Mediators/metabolism ; Male ; Organ Size/physiology ; Protective Agents/pharmacology ; Rats ; Rotenone
Czasopismo naukowe
Tytuł :
Modulation of key enzymes linked to Parkinsonism and neurologic disorders by Antiaris africana in rotenone-toxified rats.
Autorzy :
Ilesanmi OB; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, The Federal University of Technology Akure, Akure, Nigeria.; Department of Biochemistry, Faculty of Science, Federal University Otuoke, P.M.B. 126, Yenagoa, Bayelsa State, Nigeria.
Akinmoladun AC; Department of Biochemistry, Faculty of Science, Federal University Otuoke, P.M.B. 126, Yenagoa, Bayelsa State, Nigeria, Phone: +2348034445893.
Josiah SS; Department of Biochemistry, Faculty of Science, Federal University Otuoke, P.M.B. 126, Yenagoa, Bayelsa State, Nigeria.
Olaleye MT; Department of Biochemistry, Faculty of Science, Federal University Otuoke, P.M.B. 126, Yenagoa, Bayelsa State, Nigeria.
Akindahunsi AA; Department of Biochemistry, Faculty of Science, Federal University Otuoke, P.M.B. 126, Yenagoa, Bayelsa State, Nigeria.
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Źródło :
Journal of basic and clinical physiology and pharmacology [J Basic Clin Physiol Pharmacol] 2019 Dec 04; Vol. 31 (3). Date of Electronic Publication: 2019 Dec 04.
Typ publikacji :
Journal Article
MeSH Terms :
Antiaris/*chemistry
Nervous System Diseases/*drug therapy
Parkinsonian Disorders/*drug therapy
Plant Extracts/*pharmacology
Acetylcholinesterase/metabolism ; Animals ; Dopamine/metabolism ; Glutamate-Ammonia Ligase/metabolism ; Male ; Mitochondria/drug effects ; Mitochondria/metabolism ; Nervous System Diseases/chemically induced ; Nervous System Diseases/metabolism ; Neuroprotective Agents/pharmacology ; Oxidative Stress/drug effects ; Parkinsonian Disorders/chemically induced ; Parkinsonian Disorders/metabolism ; Peroxidase/metabolism ; Rats ; Rats, Wistar ; Rotenone/pharmacology ; Sodium-Potassium-Exchanging ATPase/metabolism ; Ubiquinone/analogs & derivatives ; Ubiquinone/metabolism
Czasopismo naukowe
Tytuł :
Antidiabetic property of miracle fruit plant (Synsepalum dulcificum Shumach. & Thonn. Daniell) leaf extracts in fructose-fed streptozotocin-injected rats via anti-inflammatory activity and inhibition of carbohydrate metabolizing enzymes.
Autorzy :
Obafemi TO; Phytomedicine, Biochemical Pharmacology and Toxicology Unit, Department of Biochemistry, The Federal University of Technology, PMB 704, Akure, Nigeria; Department of Chemical Sciences, Biochemistry Unit, Afe Babalola University, PMB 5454 Ado Ekiti, Nigeria. Electronic address: .
Olaleye MT; Phytomedicine, Biochemical Pharmacology and Toxicology Unit, Department of Biochemistry, The Federal University of Technology, PMB 704, Akure, Nigeria. Electronic address: .
Akinmoladun AC; Phytomedicine, Biochemical Pharmacology and Toxicology Unit, Department of Biochemistry, The Federal University of Technology, PMB 704, Akure, Nigeria. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2019 Nov 15; Vol. 244, pp. 112124. Date of Electronic Publication: 2019 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Synsepalum*
Anti-Inflammatory Agents/*therapeutic use
Diabetes Mellitus, Experimental/*drug therapy
Glycoside Hydrolase Inhibitors/*therapeutic use
Hypoglycemic Agents/*therapeutic use
Plant Extracts/*therapeutic use
Animals ; Anti-Inflammatory Agents/pharmacology ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/metabolism ; Diet ; Fructose ; Glucokinase/metabolism ; Glycoside Hydrolase Inhibitors/pharmacology ; Hexokinase/metabolism ; Hypoglycemic Agents/pharmacology ; Insulin/blood ; Interleukin-6/blood ; Liver/drug effects ; Liver/metabolism ; Male ; Plant Extracts/pharmacology ; Plant Leaves ; Rats, Wistar ; Tumor Necrosis Factor-alpha/blood
Czasopismo naukowe
Tytuł :
Glyphaea brevis - In vitro antioxidant and in silico biological activity of major constituents and molecular docking analyses.
Autorzy :
Olugbodi JO; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, PMB 704, The Federal University of Technology, Akure, Nigeria; Department of Biochemistry, Bingham University, PMB 005, Karu, Nasarawa State, Nigeria. Electronic address: .
Tincho MB; Department of Biotechnology, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa.
Oguntibeju OO; Phytomedicine and Phytochemistry Group, Oxidative Stress Research Centre, Department of Biomedical Sciences, Faculty of Health & Wellness Sciences, Cape Peninsula University of Technology, P.O. Box1906, Bellville Campus, Bellville 7535, South Africa.
Olaleye MT; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, PMB 704, The Federal University of Technology, Akure, Nigeria.
Akinmoladun AC; Phytomedicine, Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, School of Sciences, PMB 704, The Federal University of Technology, Akure, Nigeria.
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2019 Sep; Vol. 59, pp. 187-196. Date of Electronic Publication: 2019 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Malvaceae*
Antioxidants/*pharmacology
Plant Extracts/*pharmacology
Animals ; Antioxidants/chemistry ; Antioxidants/toxicity ; Lethal Dose 50 ; Mice ; Molecular Docking Simulation ; Phytochemicals/analysis ; Phytochemicals/pharmacology ; Plant Extracts/chemistry ; Plant Extracts/toxicity ; Plant Leaves ; Plant Stems ; Rats
Czasopismo naukowe

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