Autor: "Al-thamili, Dhaifallah M." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Multicomponent Domino Synthesis, Anticancer Activity and Molecular Modeling Simulation of Complex Dispirooxindolopyrrolidines.
Autorzy:: Arumugam N; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. .
Almansour AI; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. .
Suresh Kumar R; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. .
Govindasami P; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. .
Al-Thamili DM; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. .
Krishnamoorthy R; Nanobiotecnology and Molecular Biology Research Laboratory, Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Saudi Arabia. .
Periasamy VS; Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907-2084, USA. .
Alshatwi AA; Nanobiotecnology and Molecular Biology Research Laboratory, Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Saudi Arabia. .
Mahalingam SM; Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907-2084, USA. .
Thangamani S; Department of Pathology and Population Medicine, College of Veterinary Medicine, Midwestern University, Glendale, AZ 85308, USA. .
Menéndez JC; Unidad de Química Orgánica y Farmacéutica, Departamento de Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense, 28040 Madrid, Spain. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2018 May 05; Vol. 23 (5). Date of Electronic Publication: 2018 May 05.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*chemical synthesis
Indoles/*chemical synthesis
Piperidones/*chemical synthesis
Proto-Oncogene Proteins c-met/*antagonists & inhibitors
Pyrrolidines/*chemical synthesis
Spiro Compounds/*chemical synthesis
Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Binding Sites ; Bleomycin/pharmacology ; Cell Line, Tumor ; Cell Survival/drug effects ; Cycloaddition Reaction ; Drug Design ; Humans ; Imidazoles/chemistry ; Indoles/pharmacology ; Inhibitory Concentration 50 ; Lymphocytes/drug effects ; Lymphocytes/pathology ; Molecular Docking Simulation ; Piperidones/pharmacology ; Protein Binding ; Protein Interaction Domains and Motifs ; Protein Structure, Secondary ; Proto-Oncogene Proteins c-met/chemistry ; Proto-Oncogene Proteins c-met/metabolism ; Pyrrolidines/pharmacology ; Spiro Compounds/pharmacology ; Structure-Activity Relationship

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