Temat: "Alkaloids" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Recent progress in chemistry and bioactivity of monoterpenoid indole alkaloids from the genus gelsemium : a comprehensive review.
Autorzy:: Wang L; School of Pharmacy, China Medical University, Shenyang, China.
Chen S; China Medical University-Queen's University of Belfast Joint College, China Medical University, Shenyang, China.
Gao X; Jiangsu Institute Marine Resources Development, Jiangsu Ocean University, Lianyungang, China.
Liang X; School of Pharmacy, Liaoning University, Shenyang, China.
Lv W; Department of Clinical Medicine, Dalian University, Dalian, China.
Zhang D; School of Pharmacy, China Medical University, Shenyang, China.
Jin X; School of Pharmacy, China Medical University, Shenyang, China.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2155639.
Typ publikacji:: Review; Journal Article
MeSH Terms:: Secologanin Tryptamine Alkaloids*/pharmacology
Secologanin Tryptamine Alkaloids*/chemistry
Gelsemium*/chemistry
Indole Alkaloids/pharmacology ; Indole Alkaloids/chemistry ; Plant Extracts ; Pain

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Skocz do pozycji: 2.

Tytuł:: The fate of quinolizidine alkaloids during the processing of lupins (Lupinus spp.) for human consumption.
Autorzy:: Schryvers S; Department of Food Technology, Safety and Health, Faculty of Bio-Science Engineering, Ghent University, Belgium.
Arinzechukwu C; Department of Food Technology, Safety and Health, Faculty of Bio-Science Engineering, Ghent University, Belgium.
Miserez B; Ciboris, Technologiepark 90, 9052 Ghent, Belgium.
Eeckhout M; Department of Food Technology, Safety and Health, Faculty of Bio-Science Engineering, Ghent University, Belgium.
Jacxsens L; Department of Food Technology, Safety and Health, Faculty of Bio-Science Engineering, Ghent University, Belgium.; Pokaż więcej
Źródło:: Food chemistry [Food Chem] 2023 Dec 15; Vol. 429, pp. 136847. Date of Electronic Publication: 2023 Jul 12.
Typ publikacji:: Journal Article
MeSH Terms:: Alkaloids*
Lupinus*
Humans ; Quinolizidine Alkaloids ; Tandem Mass Spectrometry ; Edible Grain ; Seeds

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Skocz do pozycji: 3.

Tytuł:: Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space.
Autorzy:: Xie J; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.
Pahl A; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.; Compound Management and Screening Center (COMAS), Otto-Hahn-Straße 11, 44227, Dortmund, Germany.
Krzyzanowski A; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.; Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Straße 6, 44227, Dortmund, Germany.
Krupp A; Faculty of Chemistry, Inorganic Chemistry, TU Dortmund University, Otto-Hahn-Straße 6, 44227, Dortmund, Germany.
Liu J; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.
Koska S; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.
Schölermann B; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.
Zhang R; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.
Bonowski J; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.
Sievers S; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.; Compound Management and Screening Center (COMAS), Otto-Hahn-Straße 11, 44227, Dortmund, Germany.
Strohmann C; Faculty of Chemistry, Inorganic Chemistry, TU Dortmund University, Otto-Hahn-Straße 6, 44227, Dortmund, Germany.
Ziegler S; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.
Grigalunas M; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.
Waldmann H; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Straße 11, 44227, Dortmund, Germany.; Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Straße 6, 44227, Dortmund, Germany.; Pokaż więcej
Źródło:: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2023 Nov 27; Vol. 62 (48), pp. e202310222. Date of Electronic Publication: 2023 Oct 24.
Typ publikacji:: Journal Article
MeSH Terms:: Monoterpenes*
Alkaloids*
Indole Alkaloids

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Szczegóły

Skocz do pozycji: 4.

Tytuł:: Natural Compounds Purified from the Leaves of Aristotelia chilensis : Makomakinol, a New Alkaloid and the Effect of Aristoteline and Hobartine on Na V Channels.
Autorzy:: Pérez R; Laboratory of Natural Products & Drug Discovery, Center CEBIM, Universidad de La Frontera, Av. Francisco Salazar 01145, Temuco 4780000, Chile.
Figueredo C; Laboratory of Natural Products & Drug Discovery, Center CEBIM, Universidad de La Frontera, Av. Francisco Salazar 01145, Temuco 4780000, Chile.
Burgos V; Departamento de Ciencias Biológicas y Químicas, Facultad de Recursos Naturales, Universidad Católica de Temuco, Rudecindo Ortega 02950, Temuco 4780000, Chile.
Cabrera-Pardo JR; Laboratorio de Química Aplicada y Sustentable (LabQAS), Departamento de Química, Facultad de Ciencias, Universidad del Bío-Bío, Concepción 4081112, Chile.
Schmidt B; Institut für Chemie, Universität Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany.
Heydenreich M; Institut für Chemie, Universität Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany.
Koch A; Institut für Chemie, Universität Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany.
Deuis JR; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.
Vetter I; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.; School of Pharmacy, The University of Queensland, Woolloongabba, QLD 4102, Australia.
Paz C; Laboratory of Natural Products & Drug Discovery, Center CEBIM, Universidad de La Frontera, Av. Francisco Salazar 01145, Temuco 4780000, Chile.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 24; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 24.
Typ publikacji:: Journal Article
MeSH Terms:: Alkaloids*/pharmacology
Elaeocarpaceae*
Humans ; Indole Alkaloids ; Plant Extracts/pharmacology ; Analgesics/pharmacology ; Anti-Inflammatory Agents

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Skocz do pozycji: 5.

Tytuł:: Alscholarines A and B, two rearranged monoterpene indole alkaloids from Alstonia scholaris .
Autorzy:: Zhan G; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, P.R. China. .
Zhang F; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, P.R. China. .
Yang K; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, P.R. China. .
Yang T; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, P.R. China. .
Zhou R; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, P.R. China. .
Chen W; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, P.R. China. .
Zhang J; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, P.R. China. .
Zhang X; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, P.R. China. .
Guo Z; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, P.R. China. .; Pokaż więcej
Źródło:: Organic & biomolecular chemistry [Org Biomol Chem] 2023 Oct 18; Vol. 21 (40), pp. 8190-8196. Date of Electronic Publication: 2023 Oct 18.
Typ publikacji:: Journal Article
MeSH Terms:: Alstonia*/chemistry
Alkaloids*
Monoterpenes/pharmacology ; Indole Alkaloids/pharmacology ; Indole Alkaloids/chemistry ; Vasodilator Agents ; Molecular Structure

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Szczegóły

Skocz do pozycji: 6.

Tytuł:: Monoterpenoid indole alkaloid dimers from the Melodinus axillaris induce G2/M phase arrest and apoptosis via p38 MAPK activation in HCT116 cells.
Autorzy:: Du K; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
Li X; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
Zheng C; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
Lai L; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
Shen M; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
Wang Y; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
Meng D; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China. Electronic address: .; Pokaż więcej
Źródło:: Bioorganic chemistry [Bioorg Chem] 2023 Nov; Vol. 140, pp. 106841. Date of Electronic Publication: 2023 Sep 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apocynaceae*
Secologanin Tryptamine Alkaloids*
Humans ; HCT116 Cells ; Molecular Docking Simulation ; Apoptosis ; Cell Cycle Checkpoints ; Indole Alkaloids ; Mitosis ; Monoterpenes/pharmacology ; Polymers

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Skocz do pozycji: 7.

Tytuł:: Development and Validation of LC-MS/MS Method for Determination of Cytisine in Human Serum and Saliva.
Autorzy:: Wróblewski K; Laboratory of Commercial and Non-Commercial Clinical Trials, University of Rzeszów, Kopisto 2a, 35-959 Rzeszow, Poland.; Laboratory for Innovative Research in Pharmacology, University of Rzeszów, Kopisto 2a, 35-959 Rzeszow, Poland.; Interdisciplinary Center for Preclinical and Clinical Research, University of Rzeszów, Werynia 2A, 36-100 Kolbuszowa, Poland.
Szultka-Młyńska M; Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarina 7, 87-100 Torun, Poland.
Courtney RJ; National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052, Australia.
Buszewski B; Prof. Jan Czochralski Kuyavian-Pomeranian Science and Technology Center, Parkowa 1, 87-134 Przysiek, Poland.
Tutka P; Laboratory for Innovative Research in Pharmacology, University of Rzeszów, Kopisto 2a, 35-959 Rzeszow, Poland.; National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052, Australia.; Department of Experimental and Clinical Pharmacology, University of Rzeszów, Kopisto 2a, 35-959 Rzeszów, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 19; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 19.
Typ publikacji:: Journal Article
MeSH Terms:: Saliva*/chemistry
Alkaloids*/analysis
Humans ; Chromatography, Liquid/methods ; Tandem Mass Spectrometry/methods ; Quinolizidine Alkaloids ; Chromatography, High Pressure Liquid/methods

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Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: Monoterpenoid indole alkaloid adducts and dimers from Melodinus fusiformis.
Autorzy:: Liu ZW; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou, 510632, PR China.
Song M; School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, PR China; The First Affiliated Hospital of Jinan University, Guangzhou, 510630, PR China.
Wang JY; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou, 510632, PR China; NMPA Key Laboratory for Quality Evaluation of TCM, Jinan University, Guangzhou, 510632, PR China.
Wang DZ; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou, 510632, PR China; NMPA Key Laboratory for Quality Evaluation of TCM, Jinan University, Guangzhou, 510632, PR China.
Sun B; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou, 510632, PR China; NMPA Key Laboratory for Quality Evaluation of TCM, Jinan University, Guangzhou, 510632, PR China.
Shi L; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou, 510632, PR China; NMPA Key Laboratory for Quality Evaluation of TCM, Jinan University, Guangzhou, 510632, PR China.
Jiang RW; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou, 510632, PR China.
Ma M; School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, PR China; The First Affiliated Hospital of Jinan University, Guangzhou, 510630, PR China. Electronic address: .
Zhang XQ; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou, 510632, PR China; NMPA Key Laboratory for Quality Evaluation of TCM, Jinan University, Guangzhou, 510632, PR China. Electronic address: .; Pokaż więcej
Źródło:: Phytochemistry [Phytochemistry] 2023 Jul; Vol. 211, pp. 113678. Date of Electronic Publication: 2023 Apr 12.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*
Apocynaceae*/chemistry
Secologanin Tryptamine Alkaloids*/pharmacology
Secologanin Tryptamine Alkaloids*/chemistry
Monoterpenes/analysis ; Indole Alkaloids/pharmacology ; Indole Alkaloids/analysis ; Plant Leaves/chemistry ; Molecular Structure

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Szczegóły

Skocz do pozycji: 9.

Tytuł:: Hunteriasines A - D, tryptamine-derived alkaloids from Hunteria umbellata.
Autorzy:: Wei D; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Yang Y; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China.
Xi R; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
He Y; Process Analysis and Control Key Laboratory of Sichuan Provincial Universities, Yibin University, Yibing, 644000, China.
Igbe I; Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Benin, Benin City, 300001, Nigeria.
Wang F; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China.
Zhang G; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China. Electronic address: .
Luo Y; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China. Electronic address: .; Pokaż więcej
Źródło:: Phytochemistry [Phytochemistry] 2023 Sep; Vol. 213, pp. 113752. Date of Electronic Publication: 2023 Jun 15.
Typ publikacji:: Journal Article
MeSH Terms:: Alkaloids*/pharmacology
Apocynaceae*/chemistry
Secologanin Tryptamine Alkaloids*/chemistry
Mice ; Animals ; Indole Alkaloids/pharmacology ; Indole Alkaloids/chemistry ; Plant Extracts/chemistry ; Tryptamines/pharmacology ; Molecular Structure

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Skocz do pozycji: 10.

Tytuł:: Reversal of P-glycoprotein-mediated multidrug resistance by natural N-alkylated indole alkaloid derivatives in KB-ChR-8-5 drug-resistant cancer cells.
Autorzy:: Bharathiraja P; Department of Biochemistry and Biotechnology, Annamalai University, Annamalai Nagar, Tamil Nadu, India.
Cardoso DSP; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal.
Rajendra Prasad N; Department of Biochemistry and Biotechnology, Annamalai University, Annamalai Nagar, Tamil Nadu, India.
Mulhovo S; Centro de Estudos Moçambicanos e de Etnociências (CEMEC), Faculdade de Ciências Naturais e Matemática, Universidade Pedagógica Campus de Lhanguene, Maputo, Moçambique.
Lakra DS; Department of Biochemistry and Biotechnology, Annamalai University, Annamalai Nagar, Tamil Nadu, India.
Ferreira MU; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal.; Pokaż więcej
Źródło:: Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2023 Sep; Vol. 37 (9), pp. e23421. Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Neoplasms*/drug therapy
Alkaloids*/pharmacology
Humans ; ATP Binding Cassette Transporter, Subfamily B, Member 1 ; Colchicine/pharmacology ; Drug Resistance, Neoplasm ; Drug Resistance, Multiple ; ATP Binding Cassette Transporter, Subfamily B ; Doxorubicin/pharmacology ; Doxorubicin/therapeutic use ; ATP-Binding Cassette Transporters ; Indole Alkaloids/pharmacology ; Indole Alkaloids/therapeutic use ; Adenosine Triphosphate ; Cell Line, Tumor

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Skocz do pozycji: 11.

Tytuł:: Pharmacological investigation of indole alkaloids from Alstonia scholaris against chronic glomerulonephritis.
Autorzy:: Guo R; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650500, PR China; Chinese Materia Medica, Yunnan University of Chinese Medicine, Kunming 650500, PR China.
Shang JH; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences Kunming 650201, PR China.
Ye RH; Chinese Materia Medica, Yunnan University of Chinese Medicine, Kunming 650500, PR China.
Zhao YL; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650500, PR China. Electronic address: .
Luo XD; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650500, PR China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences Kunming 650201, PR China. Electronic address: .; Pokaż więcej
Źródło:: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2023 Sep; Vol. 118, pp. 154958. Date of Electronic Publication: 2023 Jul 08.
Typ publikacji:: Journal Article
MeSH Terms:: Alstonia*
Alkaloids*/pharmacology
Alkaloids*/therapeutic use
Glomerulonephritis*/chemically induced
Glomerulonephritis*/drug therapy
Mice ; Animals ; Mice, Inbred ICR ; Phosphatidylinositol 3-Kinases ; Proto-Oncogene Proteins c-akt ; Indole Alkaloids/pharmacology

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Skocz do pozycji: 12.

Tytuł:: A Homo-Mannich Reaction Strategy Enables Collective Access to Ibophyllidine, Aspidosperma, Kopsia, and Melodinus Alkaloids.
Autorzy:: Jiang D; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, 55 Daxuecheng South Road, Shapingba, Chongqing 401331, China.
Tang P; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, 55 Daxuecheng South Road, Shapingba, Chongqing 401331, China.
Xiong H; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, 55 Daxuecheng South Road, Shapingba, Chongqing 401331, China.
Lei S; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, 55 Daxuecheng South Road, Shapingba, Chongqing 401331, China.
Zhang Y; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, 55 Daxuecheng South Road, Shapingba, Chongqing 401331, China.
Zhang C; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, 55 Daxuecheng South Road, Shapingba, Chongqing 401331, China.
He L; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, 55 Daxuecheng South Road, Shapingba, Chongqing 401331, China.
Qiu H; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, 55 Daxuecheng South Road, Shapingba, Chongqing 401331, China.
Zhang M; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, 55 Daxuecheng South Road, Shapingba, Chongqing 401331, China.; Pokaż więcej
Źródło:: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2023 Sep 11; Vol. 62 (37), pp. e202307286. Date of Electronic Publication: 2023 Aug 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Aspidosperma*/chemistry
Apocynaceae*/chemistry
Secologanin Tryptamine Alkaloids*
Humans ; Indole Alkaloids/chemistry ; Molecular Structure

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Szczegóły

Skocz do pozycji: 13.

Tytuł:: Phytochemical Analysis and In Vitro Antileukemic Activity of Alkaloid-Enriched Extracts from Vinca sardoa (Stearn) Pignatti.
Autorzy:: De Vita D; Department of Environmental Biology, 'Sapienza' University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Frezza C; Department of Environmental Biology, 'Sapienza' University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Sciubba F; Department of Environmental Biology, 'Sapienza' University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.; NMR-Based Metabolomics Laboratory, 'Sapienza' University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Toniolo C; Department of Environmental Biology, 'Sapienza' University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Badiali C; Department of Environmental Biology, 'Sapienza' University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Petrucci R; Department of Basic and Applied Sciences for Engineering, 'Sapienza' University of Rome, Via Castro Laurenziano 7, 00161 Rome, Italy.
Bortolami M; Department of Basic and Applied Sciences for Engineering, 'Sapienza' University of Rome, Via Castro Laurenziano 7, 00161 Rome, Italy.
Di Matteo P; Department of Basic and Applied Sciences for Engineering, 'Sapienza' University of Rome, Via Castro Laurenziano 7, 00161 Rome, Italy.
Rocco D; Department of Basic and Applied Sciences for Engineering, 'Sapienza' University of Rome, Via Castro Laurenziano 7, 00161 Rome, Italy.
Stringaro A; National Center for Drug Research and Evaluation, Italian National Institute of Health, Viale Regina Elena 299, 00161 Rome, Italy.
Colone M; National Center for Drug Research and Evaluation, Italian National Institute of Health, Viale Regina Elena 299, 00161 Rome, Italy.
Maxia A; Laboratory of Economic and Pharmaceutical Botany, Department of Life and Environmental Sciences, University of Cagliari, Viale S. Ignazio da Laconi 13, 09123 Cagliari, Italy.
Petrucci MT; Department of Cellular Biotechnologies and Hematology, 'Sapienza' University of Rome, Via Benevento 6, 00161 Rome, Italy.
Serafini M; Department of Environmental Biology, 'Sapienza' University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Foddai S; Department of Environmental Biology, 'Sapienza' University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jul 25; Vol. 28 (15). Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:: Journal Article
MeSH Terms:: Vinca*
Alkaloids*/pharmacology
Antineoplastic Agents*/pharmacology
Indole Alkaloids/pharmacology ; Cell Proliferation ; Plant Extracts/pharmacology

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Skocz do pozycji: 14.

Tytuł:: Oxidative Coupling Approach to Sarpagine Alkaloids: Total Synthesis of (-)-Trinervine, Vellosimine, (+)-Normacusine B, and (-)-Alstomutinine C.
Autorzy:: Zhang Y; School of Life Sciences, Tsinghua University, Beijing, 100084, China.; National Institute of Biological Sciences, Beijing, 102206, China.
Zhang L; National Institute of Biological Sciences, Beijing, 102206, China.
Qi X; National Institute of Biological Sciences, Beijing, 102206, China.; Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, 100084, China.; Pokaż więcej
Źródło:: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2023 Jul 10; Vol. 62 (28), pp. e202304435. Date of Electronic Publication: 2023 May 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Octanes*
Alkaloids*/chemistry
Oxidative Coupling ; Stereoisomerism ; Indole Alkaloids/chemistry

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Skocz do pozycji: 15.

Tytuł:: Ormosianines A-P, Structurally Diverse Quinolizidine Alkaloids with AChE Inhibitory Effects from Ormosia yunnanensis .
Autorzy:: Jin Q; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Qin XJ; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Sun WJ; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Ding X; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Zhao Y; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Wang CB; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Tao XY; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Luo XD; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650500, People's Republic of China.; Pokaż więcej
Źródło:: Journal of natural products [J Nat Prod] 2023 Sep 22; Vol. 86 (9), pp. 2193-2205. Date of Electronic Publication: 2023 Aug 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alkaloids*/chemistry
Fabaceae*/chemistry
Acetylcholinesterase/metabolism ; Quinolizidine Alkaloids ; Molecular Docking Simulation ; Molecular Structure ; Circular Dichroism ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/chemistry

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 16.

Tytuł:: A Bischler-Napieralski and homo-Mannich sequence enables diversified syntheses of sarpagine alkaloids and analogues.
Autorzy:: Qiu H; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
Fei X; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
Yang J; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
Qiao Z; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
Yuan S; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
Zhang H; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
He L; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
Zhang M; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China. .; Pokaż więcej
Źródło:: Nature communications [Nat Commun] 2023 Sep 09; Vol. 14 (1), pp. 5560. Date of Electronic Publication: 2023 Sep 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alkaloids*/pharmacology
Biological Products*
Indole Alkaloids/pharmacology ; Drug Discovery

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 17.

Tytuł:: Targeted quantitative analysis of monoterpenoid indole alkaloids in Alstonia scholaris by ultra-high-performance liquid chromatography coupled with quadrupole time of flight mass spectrometry.
Autorzy:: Qin Y; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming, P. R. China.
He YJ; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming, P. R. China.; State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution Control, School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen, P. R. China.
Zhao YL; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming, P. R. China.
Zhou ZS; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming, P. R. China.
Wang ZJ; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming, P. R. China.
Zhu YY; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming, P. R. China.
Luo XD; Yunnan Characteristic Plant Extraction Laboratory, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming, P. R. China.; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China.; Pokaż więcej
Źródło:: Journal of separation science [J Sep Sci] 2023 Sep; Vol. 46 (17), pp. e2200843. Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:: Journal Article
MeSH Terms:: Secologanin Tryptamine Alkaloids*
Alstonia*/chemistry
Chromatography, High Pressure Liquid ; Indole Alkaloids/chemistry ; Mass Spectrometry/methods ; Monoterpenes

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 18.

Tytuł:: Sequence-Specific Dual DNA Binding Modes and Cytotoxicities of N-6-Functionalized Norcryptotackieine Alkaloids.
Autorzy:: Majhi B; Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S. C. Mullick Road, Kolkata 700032, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
Ganguly S; Department of Biophysics, Centenary Campus Bose Institute, P-1/12 C.I.T. Scheme VII-M, Kolkata 700054, India.
Palit S; Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S. C. Mullick Road, Kolkata 700032, India.
Parwez A; Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S. C. Mullick Road, Kolkata 700032, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
Saha R; Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S. C. Mullick Road, Kolkata 700032, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
Basu G; Department of Biophysics, Centenary Campus Bose Institute, P-1/12 C.I.T. Scheme VII-M, Kolkata 700054, India.
Dutta S; Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S. C. Mullick Road, Kolkata 700032, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.; Pokaż więcej
Źródło:: Journal of natural products [J Nat Prod] 2023 Jul 28; Vol. 86 (7), pp. 1667-1676. Date of Electronic Publication: 2023 Jun 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Ovarian Neoplasms*
Alkaloids*/chemistry
Quinolines*/pharmacology
Quinolines*/chemistry
Humans ; Female ; Apoptosis ; HEK293 Cells ; Cell Line, Tumor ; Indole Alkaloids/pharmacology ; DNA/chemistry

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 19.

Tytuł:: Phylogenetic patterns of bioactive secondary metabolites produced by fungal endosymbionts in morning glories (Ipomoeeae, Convolvulaceae).
Autorzy:: Quach QN; Department of Ecology and Evolutionary Biology, Tulane University, New Orleans, LA, 70118, USA.
Clay K; Department of Ecology and Evolutionary Biology, Tulane University, New Orleans, LA, 70118, USA.
Lee ST; United States Department of Agriculture, Agricultural Research Service, Logan, UT, 84341, USA.
Gardner DR; United States Department of Agriculture, Agricultural Research Service, Logan, UT, 84341, USA.
Cook D; United States Department of Agriculture, Agricultural Research Service, Logan, UT, 84341, USA.; Pokaż więcej
Źródło:: The New phytologist [New Phytol] 2023 May; Vol. 238 (4), pp. 1351-1361. Date of Electronic Publication: 2023 Mar 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Convolvulaceae*/metabolism
Convolvulaceae*/microbiology
Ipomoea*/genetics
Ipomoea*/metabolism
Ipomoea*/microbiology
Ergot Alkaloids*/metabolism
Alkaloids*/metabolism
Animals ; Swainsonine/metabolism ; Phylogeny ; Diterpene Alkaloids

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 20.

Tytuł:: Structurally diverse monoterpene indole alkaloids with vasorelaxant activities from the branches of Alstonia scholaris.
Autorzy:: Zhang F; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, PR China.
Yang K; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, PR China.
Liu H; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, PR China.
Yang T; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, PR China.
Zhou R; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, PR China.
Zhang X; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, PR China.
Zhan G; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, PR China. Electronic address: .
Guo Z; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, PR China. Electronic address: .; Pokaż więcej
Źródło:: Phytochemistry [Phytochemistry] 2023 May; Vol. 209, pp. 113610. Date of Electronic Publication: 2023 Feb 13.
Typ publikacji:: Journal Article
MeSH Terms:: Alstonia*/chemistry
Alkaloids*/pharmacology
Rats ; Animals ; Monoterpenes ; Vasodilator Agents/pharmacology ; Molecular Structure ; Indole Alkaloids/pharmacology ; Indole Alkaloids/chemistry

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