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Wyszukujesz frazę ""Alkaloids"" wg kryterium: Temat


Tytuł:
Characterization and heterologous reconstitution of Taxus biosynthetic enzymes leading to baccatin III.
Autorzy:
Jiang B; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Gao L; Beijing National Laboratory for Molecular Sciences, Peking-Tsinghua Center for Life Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.
Wang H; Beijing National Laboratory for Molecular Sciences, Peking-Tsinghua Center for Life Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.
Sun Y; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Sciences, South China Agricultural University, Guangzhou, China.
Zhang X; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Ke H; Beijing National Laboratory for Molecular Sciences, Peking-Tsinghua Center for Life Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.
Liu S; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Ma P; Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, USA.
Liao Q; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Wang Y; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Wang H; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Liu Y; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Du R; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Rogge T; Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, USA.
Li W; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Shang Y; Yunnan Key Laboratory of Potato Biology, The CAAS-YNNU-YINMORE Joint Academy of Potato Sciences, Yunnan Normal University, Kunming, China.
Houk KN; Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, USA.
Xiong X; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Xie D; Peking-Tsinghua Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Huang S; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Lei X; Beijing National Laboratory for Molecular Sciences, Peking-Tsinghua Center for Life Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.; Institute for Cancer Research, Shenzhen Bay Laboratory, Shenzhen, China.
Yan J; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Feb 09; Vol. 383 (6683), pp. 622-629. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Alkaloids*/biosynthesis
Alkaloids*/genetics
Paclitaxel*/biosynthesis
Taxoids*/metabolism
Taxus*/enzymology
Taxus*/genetics
Metabolic Engineering*
Cytochrome P-450 Enzyme System*/chemistry
Cytochrome P-450 Enzyme System*/genetics
Plant Proteins*/chemistry
Plant Proteins*/genetics
Bridged-Ring Compounds/chemistry ; Bridged-Ring Compounds/metabolism ; Ethers, Cyclic/chemistry ; Ethers, Cyclic/metabolism
Czasopismo naukowe
Tytuł:
The CYP80A and CYP80G Are Involved in the Biosynthesis of Benzylisoquinoline Alkaloids in the Sacred Lotus ( Nelumbo nucifera ).
Autorzy:
Hao C; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing 100700, China.
Yu Y; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing 100700, China.
Liu Y; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing 100700, China.
Liu A; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing 100700, China.
Chen S; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing 100700, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 05; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Nelumbo*/genetics
Benzylisoquinolines*
Alkaloids*
Aporphines*
Amino Acids
Czasopismo naukowe
Tytuł:
Veratrum parviflorum poisoning: identification of steroidal alkaloids in patient blood and breast milk.
Autorzy:
Seale JT; Department of Chemistry & Biochemistry, Boise State University, Boise, ID, USA.
Carpenter JE; Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA.; Georgia Poison Center, Atlanta, GA, USA.
Eisenstat MD; Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA.; Georgia Poison Center, Atlanta, GA, USA.; Department of Emergency Medicine, University of Louisville, Louisville, KY, USA.
Kiernan EA; Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA.; Georgia Poison Center, Atlanta, GA, USA.
Morgan BW; Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA.; Georgia Poison Center, Atlanta, GA, USA.
Nogee DP; Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA.; Georgia Poison Center, Atlanta, GA, USA.
Pu X; Biomolecular Research Center, Boise State University, Boise, ID, USA.
Therriault CA; Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA.; Georgia Poison Center, Atlanta, GA, USA.; Department of Emergency Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, USA.
Yeh M; Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA.; Georgia Poison Center, Atlanta, GA, USA.
McDougal OM; Department of Chemistry & Biochemistry, Boise State University, Boise, ID, USA.
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Źródło:
Clinical toxicology (Philadelphia, Pa.) [Clin Toxicol (Phila)] 2022 Dec; Vol. 60 (12), pp. 1309-1317. Date of Electronic Publication: 2022 Oct 27.
Typ publikacji:
Journal Article
MeSH Terms:
Veratrum*
Alkaloids*
Plant Poisoning*/drug therapy
Female ; Humans ; Milk, Human ; Veratrum Alkaloids
Czasopismo naukowe
Tytuł:
Antihypertensive Activity of the Alkaloid Aspidocarpine in Normotensive Wistar Rats.
Autorzy:
Monteiro NO; Laboratório de Tecnologia de Alimentos, CCTA, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, Brazil.
Monteiro TM; Laboratório de Clínica e Cirurgia Animal, CCTA, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes 28013-602, Brazil.
Nogueira TSR; Laboratório de Ciências Químicas, CCT, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, Brazil.
Cesar JR; Laboratório de Ciências Químicas, CCT, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, Brazil.
Nascimento LPS; Laboratório de Ciências Químicas, CCT, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, Brazil.
Campelo KA; Laboratório de Ciências Químicas, CCT, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, Brazil.
Silveira GR; Laboratório de Ciências Químicas, CCT, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, Brazil.
Antunes F; Laboratório de Clínica e Cirurgia Animal, CCTA, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes 28013-602, Brazil.
de Oliveira DB; Laboratório de Tecnologia de Alimentos, CCTA, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, Brazil.
de Carvalho Junior AR; Instituto Federal de Educação, Ciência e Tecnologia da Bahia, Vitória da Conquista, Bahia 45078-300, Brazil.
Braz-Filho R; Laboratório de Clínica e Cirurgia Animal, CCTA, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes 28013-602, Brazil.; Departamento de Química Orgânica, Instituto de Química, Universidade Federal Rural do Rio de Janeiro, Seropédica, Rio de Janeiro 20000-000, Brazil.
Vieira IJC; Laboratório de Tecnologia de Alimentos, CCTA, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, Brazil.; Laboratório de Clínica e Cirurgia Animal, CCTA, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes 28013-602, Brazil.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Oct 14; Vol. 27 (20). Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Aspidosperma*/chemistry
Alkaloids*/pharmacology
Rats ; Animals ; Rats, Wistar ; Antihypertensive Agents/pharmacology ; Indole Alkaloids/chemistry
Czasopismo naukowe
Tytuł:
New insight into the production improvement and resource generation of chaetoglobosin A in Chaetomium globosum.
Autorzy:
Zhao S; School of Life Science and Technology, Harbin Institute of Technology, Harbin, China.
Lin C; School of Life Science and Technology, Harbin Institute of Technology, Harbin, China.
Cheng M; School of Life Science and Technology, Harbin Institute of Technology, Harbin, China.
Zhang K; School of Life Science and Technology, Harbin Institute of Technology, Harbin, China.
Wang Z; School of Life Science and Technology, Harbin Institute of Technology, Harbin, China.
Zhao T; School of Life Science and Technology, Harbin Institute of Technology, Harbin, China.
Yang Q; School of Life Science and Technology, Harbin Institute of Technology, Harbin, China.
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Źródło:
Microbial biotechnology [Microb Biotechnol] 2022 Oct; Vol. 15 (10), pp. 2562-2577. Date of Electronic Publication: 2022 Aug 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alkaloids*
Polyketide Synthases*
Antiparasitic Agents ; Chaetomium ; Indole Alkaloids
SCR Organism:
Chaetomium globosum
Czasopismo naukowe
Tytuł:
Phenanthroindolizidine Alkaloids Isolated from Tylophora ovata as Potent Inhibitors of Inflammation, Spheroid Growth, and Invasion of Triple-Negative Breast Cancer.
Autorzy:
Reimche I; Department of Biomedical Sciences, Institute of Health Research and Education, University of Osnabrück, 49090 Osnabrück, Germany.; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany.
Yu H; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany.
Ariantari NP; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany.; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Udayana University, Bali 80361, Indonesia.
Liu Z; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany.
Merkens K; Department of Chemistry, University of Cologne, 50923 Cologne, Germany.
Rotfuß S; Department of Biomedical Sciences, Institute of Health Research and Education, University of Osnabrück, 49090 Osnabrück, Germany.
Peter K; Department of Biomedical Sciences, Institute of Health Research and Education, University of Osnabrück, 49090 Osnabrück, Germany.
Jungwirth U; Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath, Bath BA2 7AY, UK.
Bauer N; European Institute of Molecular Imaging, University of Münster, 48149 Münster, Germany.
Kiefer F; European Institute of Molecular Imaging, University of Münster, 48149 Münster, Germany.; Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany.
Neudörfl JM; Department of Chemistry, University of Cologne, 50923 Cologne, Germany.
Schmalz HG; Department of Chemistry, University of Cologne, 50923 Cologne, Germany.
Proksch P; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany.
Teusch N; Department of Biomedical Sciences, Institute of Health Research and Education, University of Osnabrück, 49090 Osnabrück, Germany.; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 07; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 07.
Typ publikacji:
Journal Article
MeSH Terms:
Alkaloids*/pharmacology
Alkaloids*/therapeutic use
Triple Negative Breast Neoplasms*/pathology
Animals ; Cell Line, Tumor ; Cell Proliferation ; Collagen Type I ; Humans ; Indole Alkaloids ; Indolizines ; Inflammation ; Mice ; NF-KappaB Inhibitor alpha ; NF-kappa B/pharmacology ; Paclitaxel/pharmacology ; Phenanthrenes ; Phenanthrolines ; Tumor Microenvironment ; Tylophora
Czasopismo naukowe
Tytuł:
Yellow Twig (Nauclea orientalis) from Thailand: Strictosamide as the Key Alkaloid of This Plant Species
Autorzy:
Songoen W; Department of Chemistry and Center of Excellence for Innovation in Chemistry, Special Research Unit for Advanced Magnetic Resonance, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.; Department of Organic Chemistry, University of Vienna, Währinger Strasse 38, A-1090 Vienna, Austria.
Brunmair J; Department of Analytical Chemistry, University of Vienna, Währinger Strasse 38, A-1090 Vienna, Austria.
Traxler F; Department of Organic Chemistry, University of Vienna, Währinger Strasse 38, A-1090 Vienna, Austria.
Wieser VC; Department of Botany and Biodiversity Research, University of Vienna, Rennweg 14, A-1030 Vienna, Austria.
Phanchai W; Department of Physics, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Pluempanupat W; Department of Chemistry and Center of Excellence for Innovation in Chemistry, Special Research Unit for Advanced Magnetic Resonance, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
Brecker L; Department of Organic Chemistry, University of Vienna, Währinger Strasse 38, A-1090 Vienna, Austria.
Schinnerl J; Department of Botany and Biodiversity Research, University of Vienna, Rennweg 14, A-1030 Vienna, Austria.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Aug 14; Vol. 27 (16). Date of Electronic Publication: 2022 Aug 14.
Typ publikacji:
Journal Article
MeSH Terms:
Alkaloids*/chemistry
Antineoplastic Agents*
Rubiaceae*/chemistry
Indole Alkaloids/chemistry ; Lactams ; Monoterpenes ; Thailand ; Vinca Alkaloids
Czasopismo naukowe
Tytuł:
Untargeted LC-MS/MS-Based Multi-Informative Molecular Networking for Targeting the Antiproliferative Ingredients in Tetradium ruticarpum Fruit.
Autorzy:
Su CH; Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115201, Taiwan.; Research Center for Chinese Herbal Medicine, Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 333324, Taiwan.; Department of Food Science, College of Human Ecology, Fu Jen Catholic University, New Taipei City 242062, Taiwan.
Cheng YC; Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115201, Taiwan.; Biotechnology Center in Southern Taiwan, Academia Sinica, Tainan 711010, Taiwan.
Chang YC; Research Center for Chinese Herbal Medicine, Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 333324, Taiwan.
Kung TH; Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333323, Taiwan.; Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333423, Taiwan.
Chen YL; Research Center for Chinese Herbal Medicine, Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 333324, Taiwan.; Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333323, Taiwan.
Lai KH; PhD Program in Clinical Drug Development of Herbal Medicine, College of Pharmacy, Taipei Medical University, Taipei 110301, Taiwan.; Graduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University, Taipei 110301, Taiwan.
Hsieh HL; Research Center for Chinese Herbal Medicine, Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 333324, Taiwan.; Division of Basic Medical Sciences, Department of Nursing, Chang Gung University of Science and Technology, Taoyuan 333324, Taiwan.; Department of Neurology, Chang Gung Memorial Hospital, Taoyuan 333423, Taiwan.
Chen CY; Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333323, Taiwan.; Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333423, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333323, Taiwan.
Hwang TL; Research Center for Chinese Herbal Medicine, Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 333324, Taiwan.; Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333323, Taiwan.; Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333423, Taiwan.; Department of Chemical Engineering, Ming Chi University of Technology, New Taipei City 243303, Taiwan.
Yang YL; Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115201, Taiwan.; Biotechnology Center in Southern Taiwan, Academia Sinica, Tainan 711010, Taiwan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Jul 12; Vol. 27 (14). Date of Electronic Publication: 2022 Jul 12.
Typ publikacji:
Journal Article
MeSH Terms:
Alkaloids*/analysis
Alkaloids*/pharmacology
Evodia*/chemistry
Quinolones*/analysis
Chromatography, Liquid ; Fruit/chemistry ; Humans ; Indole Alkaloids/analysis ; Indole Alkaloids/pharmacology ; Plant Extracts/chemistry ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł:
A strategy to pioneer key agent(s) in Cephalotaxus alkaloids against pan-cancer via filtering methodology based on integrated pharmacology.
Autorzy:
Oh KK; Institute for Liver and Digestive Diseases, College of Medicine, Hallym University, Chuncheon, 24252, Korea.
Yoon SJ; Institute for Liver and Digestive Diseases, College of Medicine, Hallym University, Chuncheon, 24252, Korea.
Eom JA; Institute for Liver and Digestive Diseases, College of Medicine, Hallym University, Chuncheon, 24252, Korea.
Lee KJ; Institute for Liver and Digestive Diseases, College of Medicine, Hallym University, Chuncheon, 24252, Korea.
Kwon GH; Institute for Liver and Digestive Diseases, College of Medicine, Hallym University, Chuncheon, 24252, Korea.
Kim DJ; Institute for Liver and Digestive Diseases, College of Medicine, Hallym University, Chuncheon, 24252, Korea.
Suk KT; Institute for Liver and Digestive Diseases, College of Medicine, Hallym University, Chuncheon, 24252, Korea. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Mar 10; Vol. 22 (1), pp. 262. Date of Electronic Publication: 2024 Mar 10.
Typ publikacji:
Letter
MeSH Terms:
Harringtonines*/pharmacology
Alkaloids*/pharmacology
Neoplasms*/drug therapy
Humans
Opinia redakcyjna
Tytuł:
Preparation and Evaluation of Folate Modified PEG-PLLA Nanoparticles Loaded with Lycorine for Glioma Treatment.
Autorzy:
Ding J; Department of Physiology, School of Basic Medical Sciences, Hubei University of Science and Technology, Xianning 437100, China.
Su J; Department of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning 437100, China.
Luo B; Department of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning 437100, China.
Ding L; Department of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning 437100, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 29; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
Nanoparticles*/chemistry
Glioma*
Phenanthridines*
Amaryllidaceae Alkaloids*
Humans ; Folic Acid/chemistry ; Reactive Oxygen Species ; Spectroscopy, Fourier Transform Infrared ; Polyethylene Glycols/chemistry ; Drug Carriers/chemistry ; Particle Size ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
In Vitro and In Silico of Cholinesterases Inhibition and In Vitro and In Vivo Anti-Melanoma Activity Investigations of Extracts Obtained from Selected Berberis Species.
Autorzy:
Tuzimski T; Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland.
Petruczynik A; Department of Inorganic Chemistry, Faculty of Pharmacy, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland.
Kaproń B; Department of Clinical Genetics, Faculty of Medicine, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland.
Plech T; Department of Clinical Genetics, Faculty of Medicine, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland.; Department of Pharmacology, Faculty of Health Sciences, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland.
Makuch-Kocka A; Department of Clinical Genetics, Faculty of Medicine, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland.; Department of Pharmacology, Faculty of Health Sciences, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland.
Janiszewska D; Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Torun, Poland.
Sugajski M; Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Torun, Poland.
Buszewski B; Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Torun, Poland.
Szultka-Młyńska M; Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Torun, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 28; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Berberine*/pharmacology
Berberis*
Melanoma*
Alkaloids*/pharmacology
Antineoplastic Agents*
Humans ; Acetylcholinesterase ; Butyrylcholinesterase ; Cholinesterase Inhibitors/pharmacology ; Molecular Docking Simulation ; Plant Extracts/pharmacology
Czasopismo naukowe
Tytuł:
Human Mitragynine and 7-Hydroxymitragynine Pharmacokinetics after Single and Multiple Daily Doses of Oral Encapsulated Dried Kratom Leaf Powder.
Autorzy:
Huestis MA; Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Brett MA; PK Consultant, 50259 Pulheim, Germany.
Bothmer J; JB Pharma Consulting, 6418PR Heerlen, The Netherlands.
Atallah R; Della Terra Pharmaceuticals, Atlanta, GA 30309, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 23; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Mitragyna*/metabolism
Secologanin Tryptamine Alkaloids*/metabolism
Humans ; Powders ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Plant Leaves/metabolism
Czasopismo naukowe
Tytuł:
An oxidative photocyclization approach to the synthesis of Securiflustra securifrons alkaloids.
Autorzy:
Alexander BW; Department of Chemistry, Yale University, New Haven, CT 06511, USA.
Bartfield NM; Department of Chemistry, Yale University, New Haven, CT 06511, USA.
Gupta V; Department of Chemistry, Yale University, New Haven, CT 06511, USA.
Mercado BQ; Department of Chemistry, Yale University, New Haven, CT 06511, USA.; Chemical and Biological Instrumentation Center, Yale University, New Haven, CT 06511, USA.
Del Campo M; Rigaku Americas Corporation, The Woodlands, TX 77381, USA.
Herzon SB; Department of Chemistry, Yale University, New Haven, CT 06511, USA.; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06510, USA.; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06510, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Feb 23; Vol. 383 (6685), pp. 849-854. Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Alkaloids*/chemical synthesis
Bryozoa*
Alkenes/chemistry ; Azides/chemistry ; Electrons ; Animals ; Catalysis ; Oxidation-Reduction
Czasopismo naukowe
Tytuł:
Efficacy of natural products on premature ovarian failure: a systematic review and meta-analysis of preclinical studies.
Autorzy:
Hu H; Department of Traditional Chinese Medicine, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Zhang J; Department of Traditional Chinese Medicine, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Xin X; Department of Traditional Chinese Medicine, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Jin Y; Department of Traditional Chinese Medicine, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Zhu Y; Department of Traditional Chinese Medicine, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Zhang H; Department of Traditional Chinese Medicine, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Fan R; Department of Traditional Chinese Medicine, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Ye Y; Department of Traditional Chinese Medicine, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China. .
Li D; Department of Traditional Chinese Medicine, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China. .
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Źródło:
Journal of ovarian research [J Ovarian Res] 2024 Feb 20; Vol. 17 (1), pp. 46. Date of Electronic Publication: 2024 Feb 20.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article; Review
MeSH Terms:
Primary Ovarian Insufficiency*/therapy
Menopause, Premature*
Alkaloids*/therapeutic use
Female ; Humans ; Animals ; Flavonoids/pharmacology ; Phenols ; Peptides/therapeutic use
Czasopismo naukowe
Tytuł:
Cyclodextrin-Enabled Enantioselective Complexation Study of Cathinone Analogs.
Autorzy:
Dohárszky A; Department of Pharmacognosy, Semmelweis University, Üllői út 26, H-1085 Budapest, Hungary.
Kalydi E; Department of Pharmacognosy, Semmelweis University, Üllői út 26, H-1085 Budapest, Hungary.; Department of Organic Chemistry, Semmelweis University, Hőgyes Endre utca 7, H-1092 Budapest, Hungary.
Völgyi G; Department of Pharmaceutical Chemistry, Semmelweis University, Hőgyes Endre utca 7, H-1092 Budapest, Hungary.
Béni S; Department of Pharmacognosy, Semmelweis University, Üllői út 26, H-1085 Budapest, Hungary.; Department of Analytical Chemistry, Institute of Chemistry, ELTE Eötvös Loránd University, Pázmány Péter sétány 1/A, H-1117 Budapest, Hungary.
Fejős I; Department of Pharmacognosy, Semmelweis University, Üllői út 26, H-1085 Budapest, Hungary.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 16; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
Cyclodextrins*/chemistry
Alkaloids*
Stereoisomerism ; Magnetic Resonance Spectroscopy/methods
Czasopismo naukowe
Tytuł:
Comparative antioxidant activity and phytochemical content of five extracts of Pleurotus ostreatus (oyster mushroom).
Autorzy:
Effiong ME; Department of Biochemistry, College of Science and Technology, Covenant University, Canaanland, PMB 1023, Ota, Ogun State, Nigeria. .; Covenant Applied Informatics and Communication Africa Centre of Excellence (CApIC-ACE), Covenant University, Canaanland, PMB 1023, Ota, Ogun State, Nigeria. .
Umeokwochi CP; Department of Biochemistry, College of Science and Technology, Covenant University, Canaanland, PMB 1023, Ota, Ogun State, Nigeria.
Afolabi IS; Department of Biochemistry, College of Science and Technology, Covenant University, Canaanland, PMB 1023, Ota, Ogun State, Nigeria.; Covenant University Public Health and Wellbeing Research Cluster (CUPHWERC) Covenant University, Canaanland, PMB 1023, Ota, Ogun State, Nigeria.
Chinedu SN; Department of Biochemistry, College of Science and Technology, Covenant University, Canaanland, PMB 1023, Ota, Ogun State, Nigeria.; Covenant University Public Health and Wellbeing Research Cluster (CUPHWERC) Covenant University, Canaanland, PMB 1023, Ota, Ogun State, Nigeria.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 15; Vol. 14 (1), pp. 3794. Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Pleurotus*
Alkaloids*
Saponins*
Antioxidants/pharmacology ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Chloroform ; Phytochemicals/pharmacology ; Flavonoids/pharmacology
Czasopismo naukowe
Tytuł:
Polyphenols: Role in Modulating Immune Function and Obesity.
Autorzy:
Mamun MAA; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, TN 38163, USA.
Rakib A; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, TN 38163, USA.
Mandal M; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, TN 38163, USA.
Kumar S; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, TN 38163, USA.
Singla B; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, TN 38163, USA.
Singh UP; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, TN 38163, USA.
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Źródło:
Biomolecules [Biomolecules] 2024 Feb 14; Vol. 14 (2). Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Polyphenols*/pharmacology
Polyphenols*/therapeutic use
Polyphenols*/metabolism
Alkaloids*
Humans ; Obesity/metabolism ; Flavonoids ; Immunity
Czasopismo naukowe
Tytuł:
Combined administration of anisodamine and neostigmine alleviated colitis by inducing autophagy and inhibiting inflammation.
Autorzy:
Liu M; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.; Air Force Hangzhou Special Service Recuperation Center Sanatorium Area 4, Nanjing, China.
Zhu D; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Yan H; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Dong Z; Department of General Surgery, Air Force Medical Center, PLA, Beijing, China.
Zhang J; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Kong N; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Zhang G; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Xu Q; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Han T; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Ke P; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.; Air Force Hangzhou Special Service Recuperation Center Sanatorium Area 4, Nanjing, China.
Liu C; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
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Źródło:
PloS one [PLoS One] 2024 Feb 14; Vol. 19 (2), pp. e0291543. Date of Electronic Publication: 2024 Feb 14 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Neostigmine*/adverse effects
Colitis*/chemically induced
Colitis*/drug therapy
Colitis*/metabolism
Solanaceous Alkaloids*
Mice ; Animals ; Humans ; Tumor Necrosis Factor-alpha/metabolism ; alpha7 Nicotinic Acetylcholine Receptor/metabolism ; Interleukin-6/metabolism ; Caco-2 Cells ; Inflammation/drug therapy ; Inflammation/metabolism ; Autophagy ; Dextran Sulfate/toxicity ; Colon/metabolism ; Mice, Inbred C57BL ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Genomic and Comparative Transcriptomic Analyses Reveal Key Genes Associated with the Biosynthesis Regulation of Okaramine B in Penicillium daleae NBP-49626.
Autorzy:
Wang Y; National Biopesticide Engineering Technology Research Centre, Hubei Biopesticide Engineering Research Centre, Key Laboratory of Microbial Pesticides, Ministry of Agriculture and Rural Affairs, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
Chen L; National Biopesticide Engineering Technology Research Centre, Hubei Biopesticide Engineering Research Centre, Key Laboratory of Microbial Pesticides, Ministry of Agriculture and Rural Affairs, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
Fang W; National Biopesticide Engineering Technology Research Centre, Hubei Biopesticide Engineering Research Centre, Key Laboratory of Microbial Pesticides, Ministry of Agriculture and Rural Affairs, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
Zeng Z; National Biopesticide Engineering Technology Research Centre, Hubei Biopesticide Engineering Research Centre, Key Laboratory of Microbial Pesticides, Ministry of Agriculture and Rural Affairs, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
Wu Z; National Biopesticide Engineering Technology Research Centre, Hubei Biopesticide Engineering Research Centre, Key Laboratory of Microbial Pesticides, Ministry of Agriculture and Rural Affairs, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
Liu F; National Biopesticide Engineering Technology Research Centre, Hubei Biopesticide Engineering Research Centre, Key Laboratory of Microbial Pesticides, Ministry of Agriculture and Rural Affairs, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
Liu X; National Biopesticide Engineering Technology Research Centre, Hubei Biopesticide Engineering Research Centre, Key Laboratory of Microbial Pesticides, Ministry of Agriculture and Rural Affairs, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
Gong Y; National Biopesticide Engineering Technology Research Centre, Hubei Biopesticide Engineering Research Centre, Key Laboratory of Microbial Pesticides, Ministry of Agriculture and Rural Affairs, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
Zhu L; National Biopesticide Engineering Technology Research Centre, Hubei Biopesticide Engineering Research Centre, Key Laboratory of Microbial Pesticides, Ministry of Agriculture and Rural Affairs, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
Wang K; National Biopesticide Engineering Technology Research Centre, Hubei Biopesticide Engineering Research Centre, Key Laboratory of Microbial Pesticides, Ministry of Agriculture and Rural Affairs, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 06; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 06.
Typ publikacji:
Journal Article
MeSH Terms:
Penicillium*/metabolism
Azetidines*
Azocines*
Indole Alkaloids*
Gene Expression Profiling ; Genomics/methods
SCR Organism:
Penicillium daleae
Czasopismo naukowe
Tytuł:
Hypoglycemic Effects and Quality Marker Screening of Dendrobium nobile Lindl. at Different Growth Years.
Autorzy:
Luo Y; Key Lab of the Basic Pharmacology of The Ministry of Education, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.
Yang D; Key Lab of the Basic Pharmacology of The Ministry of Education, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.
Xu Y; Key Lab of the Basic Pharmacology of The Ministry of Education, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.
Wu D; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.
Tan D; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.
Qin L; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.
Wu X; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.
Lu Y; Key Lab of the Basic Pharmacology of The Ministry of Education, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.
He Y; Key Lab of the Basic Pharmacology of The Ministry of Education, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi 563009, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 02; Vol. 29 (3). Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Dendrobium*
Diabetes Mellitus, Experimental*/drug therapy
Alkaloids*/analysis
Sesquiterpenes*
Animals ; Mice ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Glycosides
Czasopismo naukowe

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