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Wyszukujesz frazę ""Alpha subunits"" wg kryterium: Temat


Tytuł:
Gα12 and endoplasmic reticulum stress-mediated pyroptosis in a single cycle of dextran sulfate-induced mouse colitis.
Autorzy:
Tak J; College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University-Seoul, Goyang-si, Gyeonggi-do, 10326, Republic of Korea.
An Q; College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University-Seoul, Goyang-si, Gyeonggi-do, 10326, Republic of Korea.
Lee SG; Research and Development Institute, A Pharma Inc, Goyang-si, Gyeonggi-do, 10326, Republic of Korea.
Lee CH; College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University-Seoul, Goyang-si, Gyeonggi-do, 10326, Republic of Korea.
Kim SG; College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University-Seoul, Goyang-si, Gyeonggi-do, 10326, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 15; Vol. 14 (1), pp. 6335. Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:
Journal Article
MeSH Terms:
Colitis*/metabolism
Colitis*/pathology
GTP-Binding Protein alpha Subunits, G12-G13*/metabolism
Animals ; Mice ; Dextran Sulfate/toxicity ; Disease Models, Animal ; Endoplasmic Reticulum Stress ; Endoribonucleases/genetics ; Endoribonucleases/metabolism ; Inflammatory Bowel Diseases/metabolism ; Inflammatory Bowel Diseases/pathology ; Mice, Inbred C57BL ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; Pyroptosis
Czasopismo naukowe
Tytuł:
A Rare Skeletal Disorder, Fibrous Dysplasia: A Review of Its Pathogenesis and Therapeutic Prospects.
Autorzy:
Kim HY; Interdisciplinary Program in Bioengineering, Seoul National University, Seoul 08826, Republic of Korea.; Department of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
Shim JH; Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea.; Department of Research Administration Team, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea.
Heo CY; Interdisciplinary Program in Bioengineering, Seoul National University, Seoul 08826, Republic of Korea.; Department of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.; Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 26; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
GTP-Binding Protein alpha Subunits, Gs*/metabolism
Fibrous Dysplasia of Bone*/therapy
Fibrous Dysplasia of Bone*/pathology
Humans ; Bone and Bones/metabolism ; Cell Communication
Czasopismo naukowe
Tytuł:
Beyond the G protein α subunit: investigating the functional impact of other components of the Gαi 3 heterotrimers.
Autorzy:
Rysiewicz B; Department of Physical Biochemistry, Faculty of Biochemistry Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387, Kraków, Poland.
Błasiak E; Department of Physical Biochemistry, Faculty of Biochemistry Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387, Kraków, Poland.
Mystek P; Department of Physical Biochemistry, Faculty of Biochemistry Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387, Kraków, Poland.
Dziedzicka-Wasylewska M; Department of Physical Biochemistry, Faculty of Biochemistry Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387, Kraków, Poland.
Polit A; Department of Physical Biochemistry, Faculty of Biochemistry Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387, Kraków, Poland. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2023 Oct 10; Vol. 21 (1), pp. 279. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
GTP-Binding Protein alpha Subunits*/metabolism
GTP-Binding Protein gamma Subunits*/metabolism
GTP-Binding Proteins/metabolism ; Signal Transduction ; Carrier Proteins/metabolism ; Receptors, G-Protein-Coupled/metabolism
Czasopismo naukowe
Tytuł:
Whole-genome sequencing revealed a novel long-range deletion mutation spanning GNAS in familial pseudohypoparathyroidism.
Autorzy:
Fei Y; Department of Endocrinology and Metabolism, Meishan Municipal People's Hospital, Sichuan, China.
Liu L; Department of Endocrinology and Metabolism, Meishan Municipal People's Hospital, Sichuan, China.
Wu L; Department of Endocrinology and Metabolism, Meishan Municipal People's Hospital, Sichuan, China.
Wang O; Department of Endocrinology, Key Laboratory of Endocrinology, National Health Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.
Xing X; Department of Endocrinology, Key Laboratory of Endocrinology, National Health Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.
Li A; Department of Endocrinology and Metabolism, Meishan Municipal People's Hospital, Sichuan, China.
Huang L; Department of Endocrinology and Metabolism, Meishan Municipal People's Hospital, Sichuan, China.
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Źródło:
Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2023 May; Vol. 11 (5), pp. e2144. Date of Electronic Publication: 2023 Jan 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
GTP-Binding Protein alpha Subunits, Gs*/genetics
Pseudohypoparathyroidism*/genetics
Pseudohypoparathyroidism*/diagnosis
Female ; Humans ; DNA Methylation ; Chromogranins/genetics ; Sequence Deletion
Czasopismo naukowe
Tytuł:
Structural and Functional Implication of Natural Variants of Gαs.
Autorzy:
Jeong Y; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Chung KY; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 17; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
GTP-Binding Protein alpha Subunits, Gs*/chemistry
GTP-Binding Protein alpha Subunits, Gs*/genetics
GTP-Binding Protein alpha Subunits, Gs*/metabolism
Guanosine Diphosphate/metabolism ; Guanosine Triphosphate/metabolism ; Parathyroid Hormone/metabolism ; Signal Transduction ; Humans ; Pseudohypoparathyroidism/genetics ; Protein Conformation
Czasopismo naukowe
Tytuł:
Generation of Gαi knock-out HEK293 cells illuminates Gαi-coupling diversity of GPCRs.
Autorzy:
Ono Y; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan.
Kawakami K; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan.
Nakamura G; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan.
Ishida S; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan.
Aoki J; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Inoue A; Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, 980-8578, Japan. .
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Źródło:
Communications biology [Commun Biol] 2023 Jan 28; Vol. 6 (1), pp. 112. Date of Electronic Publication: 2023 Jan 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, G-Protein-Coupled*/genetics
Receptors, G-Protein-Coupled*/metabolism
GTP-Binding Protein alpha Subunits, Gi-Go*/genetics
GTP-Binding Protein alpha Subunits, Gi-Go*/metabolism
Humans ; HEK293 Cells ; Ligands ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł:
RUNX3 in Stem Cell and Cancer Biology.
Autorzy:
Chuang LSH; Cancer Science Institute of Singapore, NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive #12-01, Singapore 117599, Singapore.
Matsuo J; Cancer Science Institute of Singapore, NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive #12-01, Singapore 117599, Singapore.
Douchi D; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Bte Mawan NA; Cancer Science Institute of Singapore, NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive #12-01, Singapore 117599, Singapore.
Ito Y; Cancer Science Institute of Singapore, NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive #12-01, Singapore 117599, Singapore.
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Źródło:
Cells [Cells] 2023 Jan 25; Vol. 12 (3). Date of Electronic Publication: 2023 Jan 25.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Core Binding Factor alpha Subunits*/genetics
Core Binding Factor alpha Subunits*/metabolism
Neoplasms*/genetics
Animals ; Mice ; Biology ; Mammals/metabolism ; Mutation ; Signal Transduction ; Humans
Czasopismo naukowe
Tytuł:
The RUNX Family, a Novel Multifaceted Guardian of the Genome.
Autorzy:
Dutta B; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Osato M; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.; International Research Center for Medical Sciences, Kumamoto University, Kumamoto 860-0811, Japan.
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Źródło:
Cells [Cells] 2023 Jan 07; Vol. 12 (2). Date of Electronic Publication: 2023 Jan 07.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Core Binding Factor alpha Subunits*/genetics
Core Binding Factor alpha Subunits*/metabolism
Neoplasms*/genetics
Female ; Pregnancy ; Humans ; Transcription Factors/metabolism ; Genome ; Gene Expression Regulation
Czasopismo naukowe
Tytuł:
Structures in G proteins important for subtype selective receptor binding and subsequent activation.
Autorzy:
Jelinek V; Institute of Pharmacology and Clinical Pharmacy, Philipps-University Marburg, Marburg, Germany.
Mösslein N; Institute of Pharmacology and Clinical Pharmacy, Philipps-University Marburg, Marburg, Germany.
Bünemann M; Institute of Pharmacology and Clinical Pharmacy, Philipps-University Marburg, Marburg, Germany. .
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Źródło:
Communications biology [Commun Biol] 2021 May 27; Vol. 4 (1), pp. 635. Date of Electronic Publication: 2021 May 27.
Typ publikacji:
Journal Article
MeSH Terms:
GTP-Binding Protein alpha Subunits/*metabolism
GTP-Binding Protein alpha Subunits/*ultrastructure
Receptors, G-Protein-Coupled/*metabolism
Animals ; GTP-Binding Protein alpha Subunits/physiology ; GTP-Binding Protein alpha Subunits, Gq-G11/metabolism ; GTP-Binding Protein alpha Subunits, Gq-G11/physiology ; GTP-Binding Protein alpha Subunits, Gq-G11/ultrastructure ; GTP-Binding Proteins/metabolism ; GTP-Binding Proteins/physiology ; GTP-Binding Proteins/ultrastructure ; Humans ; Mice ; Protein Binding ; Rats ; Receptors, G-Protein-Coupled/physiology ; Receptors, G-Protein-Coupled/ultrastructure ; Signal Transduction
Czasopismo naukowe
Tytuł:
RUNX Proteins as Epigenetic Modulators in Cancer.
Autorzy:
Yi H; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.; Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.; National Clinical Research Centre for Infectious Diseases, The Third People's Hospital of Shenzhen and The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen 518112, China.
He Y; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.; Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.
Zhu Q; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.; Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.
Fang L; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.; Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.; Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology, Shenzhen 518005, China.
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Źródło:
Cells [Cells] 2022 Nov 20; Vol. 11 (22). Date of Electronic Publication: 2022 Nov 20.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Core Binding Factor alpha Subunits*/genetics
Core Binding Factor alpha Subunits*/metabolism
Neoplasms*/metabolism
Humans ; Epigenomics ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Epigenesis, Genetic
Czasopismo naukowe
Tytuł:
The Roles of RUNX Proteins in Lymphocyte Function and Anti-Tumor Immunity.
Autorzy:
Seo W; RIKEN Center for Integrative Medical Sciences, Laboratory for Transcriptional Regulation, Yokohama 230-0045, Japan.; Department of Immunology, Graduate School of Medicine, Nagoya University, Nagoya 466-8550, Japan.
Nomura A; RIKEN Center for Integrative Medical Sciences, Laboratory for Transcriptional Regulation, Yokohama 230-0045, Japan.
Taniuchi I; RIKEN Center for Integrative Medical Sciences, Laboratory for Transcriptional Regulation, Yokohama 230-0045, Japan.
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Źródło:
Cells [Cells] 2022 Oct 03; Vol. 11 (19). Date of Electronic Publication: 2022 Oct 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Core Binding Factor alpha Subunits*/genetics
Core Binding Factor alpha Subunits*/metabolism
Neoplasms*/genetics
Animals ; Immunity ; Lymphocytes/metabolism ; Mammals/metabolism ; Transcription Factors
Czasopismo naukowe
Tytuł:
RUNX Family in Hypoxic Microenvironment and Angiogenesis in Cancers.
Autorzy:
Lee YM; Vessel-Organ Interaction Research Center, VOICE (MRC), Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Korea.; Lab of Molecular Pathophysiology, College of Pharmacy, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Korea.
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Źródło:
Cells [Cells] 2022 Oct 01; Vol. 11 (19). Date of Electronic Publication: 2022 Oct 01.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Core Binding Factor alpha Subunits*/genetics
Core Binding Factor alpha Subunits*/metabolism
Neoplasms*/genetics
Carcinogenesis ; Humans ; Hypoxia ; Morphogenesis ; Neovascularization, Pathologic ; Transcription Factors/physiology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion.
Autorzy:
Chaim OM; Department of Pharmacology, University of California San Diego, Biomedical Sciences Building, 9500 Gilman Drive #0636, La Jolla, CA, 92093-0636, USA. .; Department of Cell Biology, Federal University of Paraná, Curitiba, Brazil. .
Miki S; Department of Medicine, University of California San Diego, La Jolla, CA, USA.; Ludwig Institute for Cancer Research, San Diego Branch, La Jolla, CA, USA.
Prager BC; Department of Medicine, University of California San Diego, La Jolla, CA, USA.; Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, Cleveland, OH, USA.
Ma J; Department of Medicine, University of California San Diego, La Jolla, CA, USA.; Ludwig Institute for Cancer Research, San Diego Branch, La Jolla, CA, USA.
Jeong AY; Department of Pharmacology, University of California San Diego, Biomedical Sciences Building, 9500 Gilman Drive #0636, La Jolla, CA, 92093-0636, USA.
Lara J; Department of Pharmacology, University of California San Diego, Biomedical Sciences Building, 9500 Gilman Drive #0636, La Jolla, CA, 92093-0636, USA.
Tran NK; Department of Pharmacology, University of California San Diego, Biomedical Sciences Building, 9500 Gilman Drive #0636, La Jolla, CA, 92093-0636, USA.
Smith JM; Department of Pharmacology, University of California San Diego, Biomedical Sciences Building, 9500 Gilman Drive #0636, La Jolla, CA, 92093-0636, USA.
Rich JN; Department of Medicine, University of California San Diego, La Jolla, CA, USA.; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Gutkind JS; Department of Pharmacology, University of California San Diego, Biomedical Sciences Building, 9500 Gilman Drive #0636, La Jolla, CA, 92093-0636, USA.; Moores Cancer Center, University of California at San Diego, La Jolla, CA, USA.
Miyamoto S; Department of Pharmacology, University of California San Diego, Biomedical Sciences Building, 9500 Gilman Drive #0636, La Jolla, CA, 92093-0636, USA.
Furnari FB; Department of Medicine, University of California San Diego, La Jolla, CA, USA.; Ludwig Institute for Cancer Research, San Diego Branch, La Jolla, CA, USA.
Brown JH; Department of Pharmacology, University of California San Diego, Biomedical Sciences Building, 9500 Gilman Drive #0636, La Jolla, CA, 92093-0636, USA.
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 16; Vol. 13 (1), pp. 22412. Date of Electronic Publication: 2023 Dec 16.
Typ publikacji:
Journal Article
MeSH Terms:
Glioblastoma*/genetics
Glioblastoma*/pathology
Brain Neoplasms*/genetics
Brain Neoplasms*/pathology
Humans ; Animals ; Mice ; GTP-Binding Protein alpha Subunits, G12-G13/genetics ; GTP-Binding Protein alpha Subunits, G12-G13/metabolism ; Signal Transduction ; Neoplastic Processes ; Up-Regulation ; Cell Line, Tumor ; Cell Proliferation
Czasopismo naukowe
Tytuł:
Clinical Cases and the Molecular Profiling of a Novel Childhood Encephalopathy-Causing GNAO1 Mutation P170R.
Autorzy:
Larasati YA; Translational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.
Solis GP; Translational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.
Koval A; Translational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.
Griffiths ST; Department of Pediatrics, Haukeland University Hospital, 5009 Bergen, Norway.
Berentsen R; Department of Medical Genetics, Haukeland University Hospital, 5009 Bergen, Norway.
Aukrust I; Department of Medical Genetics, Haukeland University Hospital, 5009 Bergen, Norway.; Department of Clinical Science, University of Bergen, 5008 Bergen, Norway.
Lesca G; Department of Medical Genetics, University Hospital of Lyon, 69002 Lyon, France.
Chatron N; Department of Medical Genetics, University Hospital of Lyon, 69002 Lyon, France.
Ville D; Pediatric Neurology Department, University Hospital of Lyon, 69002 Lyon, France.
Korff CM; Pediatric Neurology Unit, University Hospitals of Geneva, CH-1211 Geneva, Switzerland.
Katanaev VL; Translational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.; Institute of Life Sciences and Biomedicine, Far Eastern Federal University, Vladivostok 690090, Russia.
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Źródło:
Cells [Cells] 2023 Oct 17; Vol. 12 (20). Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Diseases*
Humans ; Child ; Mutation/genetics ; GTP-Binding Proteins/metabolism ; Ions/metabolism ; Guanosine Triphosphate ; GTP-Binding Protein alpha Subunits, Gi-Go/genetics ; GTP-Binding Protein alpha Subunits, Gi-Go/metabolism
Czasopismo naukowe
Tytuł:
Exploring pharmacological inhibition of G q/11 as an analgesic strategy.
Autorzy:
Marwari S; Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida, USA.
Kowalski C; Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida, USA.
Martemyanov KA; Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida, USA.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2022 Dec; Vol. 179 (23), pp. 5196-5208. Date of Electronic Publication: 2022 Aug 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Analgesics*/pharmacology
Analgesics*/therapeutic use
Analgesics, Opioid*/pharmacology
Analgesics, Opioid*/therapeutic use
GTP-Binding Protein alpha Subunits, Gq-G11*/antagonists & inhibitors
Animals ; Mice ; Morphine/pharmacology ; Morphine/therapeutic use ; Pain/drug therapy ; Receptors, Opioid
Czasopismo naukowe
Tytuł:
Long noncoding RNA KCNMA1-AS1 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by activating the SMAD9 signaling pathway.
Autorzy:
Mai Z; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong, China.
Liu J; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong, China.
Jiang X; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong, China.
Gu W; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong, China.
Wang W; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong, China.
Li S; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong, China.
Schmalz G; Department of Cariology, Endodontology and Periodontology, University of Leipzig, 04103, Leipzig, Germany.
Xiao H; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong, China. .
Zhao J; Shenzhen Stomatological Hospital, Southern Medical University, Shenzhen, Guangdong, China. .
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Źródło:
Biology direct [Biol Direct] 2023 Nov 29; Vol. 18 (1), pp. 81. Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Mesenchymal Stem Cells*/metabolism
Humans ; Osteogenesis/genetics ; Cell Differentiation/genetics ; Signal Transduction/genetics ; Smad8 Protein/metabolism ; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits/metabolism
Czasopismo naukowe
Tytuł:
Photoperiod Induces the Epigenetic Change of the GNAQ Gene in OVX+E 2 Ewes.
Autorzy:
Wang W; State Key Laboratory of Animal Biotech Breeding, Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China.
Du X; State Key Laboratory of Animal Biotech Breeding, Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China.
Chu M; State Key Laboratory of Animal Biotech Breeding, Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China.
He X; State Key Laboratory of Animal Biotech Breeding, Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 17; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Epigenesis, Genetic*
Photoperiod*
Animals ; Female ; Gonadotropin-Releasing Hormone/metabolism ; Histones/genetics ; Histones/metabolism ; Hypothalamus/metabolism ; Mammals/metabolism ; Sheep/genetics ; GTP-Binding Protein alpha Subunits, Gq-G11
Czasopismo naukowe
Tytuł:
Single-Nucleotide Polymorphism in Genes Encoding G Protein Subunits GNB3 and GNAQ Increase the Risk of Cardiovascular Morbidity among Patients Undergoing Renal Replacement Therapy.
Autorzy:
Birkner S; Department of Nephrology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.
Möhlendick B; Institute of Pharmacogenetics, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Wilde B; Department of Nephrology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.
Schoenfelder K; Department of Nephrology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.
Boss K; Department of Nephrology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.
Siffert W; Institute of Pharmacogenetics, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Kribben A; Department of Nephrology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.
Friebus-Kardash J; Department of Nephrology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 17; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Coronary Stenosis*
Heterotrimeric GTP-Binding Proteins*/genetics
Humans ; Male ; Genotype ; GTP-Binding Protein alpha Subunits, Gq-G11/genetics ; Polymorphism, Single Nucleotide ; Protein Subunits/genetics ; Renal Dialysis/adverse effects ; Renal Replacement Therapy ; Female
Czasopismo naukowe
Tytuł:
The long and winding road to personalized medicine in KCNMA1-linked channelopathies revealed by novel variants associated with the Liang-Wang syndrome.
Autorzy:
Soldovieri MV; Department of Medicine and Health Sciences 'Vincenzo Tiberio', University of Molise, Campobasso, Italy.
Taglialatela M; Department of Neuroscience, University of Naples 'Federico II', Naples, Italy.
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Źródło:
Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2022 Aug; Vol. 235 (4), pp. e13854. Date of Electronic Publication: 2022 Jun 28.
Typ publikacji:
Editorial
MeSH Terms:
Channelopathies*/genetics
Large-Conductance Calcium-Activated Potassium Channel alpha Subunits*/genetics
Humans ; Precision Medicine
Opinia redakcyjna
Tytuł:
Functional coupling of M 1 muscarinic acetylcholine receptor to Gα q/11 in dorsolateral prefrontal cortex from patients with psychiatric disorders: a postmortem study.
Autorzy:
Odagaki Y; Department of Psychiatry, Faculty of Medicine, Saitama Medical University, 38 Morohongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan. .
Kinoshita M; Department of Psychiatry, Faculty of Medicine, Saitama Medical University, 38 Morohongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan.
Meana JJ; Department of Pharmacology, University of the Basque Country, UPV/EHU, 48940, Leioa, Bizkaia, Spain.; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Bilbao, Spain.
Callado LF; Department of Pharmacology, University of the Basque Country, UPV/EHU, 48940, Leioa, Bizkaia, Spain.; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Bilbao, Spain.
García-Sevilla JA; Laboratory of Neuropharmacology, IUNICS/IdISPa, University of the Balearic Islands (UIB), Palma de Mallorca, Spain.
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Źródło:
European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2020 Oct; Vol. 270 (7), pp. 869-880. Date of Electronic Publication: 2019 Dec 05.
Typ publikacji:
Journal Article
MeSH Terms:
Signal Transduction*
Bipolar Disorder/*metabolism
Depressive Disorder, Major/*metabolism
GTP-Binding Protein alpha Subunits/*metabolism
Prefrontal Cortex/*metabolism
Receptor, Muscarinic M1/*metabolism
Schizophrenia/*metabolism
Adult ; Aged ; Autopsy ; Carbachol/pharmacology ; Cohort Studies ; Female ; GTP-Binding Protein alpha Subunits, Gi-Go/metabolism ; Humans ; Male ; Middle Aged
Czasopismo naukowe

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