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Wyszukujesz frazę ""Alternative Splicing"" wg kryterium: Temat


Tytuł :
A variant of H19 transcript regulates EMT and oral cancer progression.
Autorzy :
Zhou W; School of Medicine, Jiaxing University, Jiaxing, China.
Wang XZ; Vocational & Technical College, Lishui University, Lishui, China.
Fang BM; Lishui City People's Hospital, Lishui, China.
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Źródło :
Oral diseases [Oral Dis] 2022 Jan; Vol. 28 (1), pp. 116-124. Date of Electronic Publication: 2020 Dec 12.
Typ publikacji :
Journal Article
MeSH Terms :
Alternative Splicing*
Epithelial-Mesenchymal Transition*/genetics
Mouth Neoplasms*/genetics
RNA, Long Noncoding*/genetics
Carcinogenesis ; Cell Line, Tumor ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe
Tytuł :
Gene regulatory network analysis defines transcriptome landscape with alternative splicing of human umbilical vein endothelial cells during replicative senescence.
Autorzy :
Ohori M; Research, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, Japan. .
Nakayama Y; Research, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, Japan.; Present address: Discovery Technology Research Laboratories, Tsukuba Research Institute, Ono Pharmaceutical Co., Ltd, 17-2 Wadai, 300-4247, Tsukuba, Ibaraki, Japan.
Ogasawara-Shimizu M; Research, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, Japan.
Toyoshiba H; Research, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, Japan.; Present address: Life Science AI, FRONTEO Healthcare Inc., 2-12-23 Konan, Minato-ku, 108-0075, Tokyo, Japan.
Nakanishi A; Research, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, Japan.
Aparicio S; Molecular Oncology, BC Cancer Agency, 675 W10th Avenue, V5Z 1L3, Vancouver, BC, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, V6T 2B5, Vancouver, BC, Canada.
Araki S; Research, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, Japan. .
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Źródło :
BMC genomics [BMC Genomics] 2021 Dec 02; Vol. 22 (1), pp. 869. Date of Electronic Publication: 2021 Dec 02.
Typ publikacji :
Journal Article
MeSH Terms :
Alternative Splicing*
Gene Regulatory Networks*
Cellular Senescence/genetics ; Human Umbilical Vein Endothelial Cells ; Humans ; Transcriptome
Czasopismo naukowe
Tytuł :
Stabilization of negative activation voltages of Cav1.3 L-Type Ca -channels by alternative splicing.
Autorzy :
Hofer NT; Department of Pharmacology and Toxicology, Centre for Molecular Biosciences, University of Innsbruck , Austria.
Pinggera A; Neurobiology Division, MRC Laboratory of Molecular Biology , Cambridge, UK.
Nikonishyna YV; Department of Pharmacology and Toxicology, Centre for Molecular Biosciences, University of Innsbruck , Austria.
Tuluc P; Department of Pharmacology and Toxicology, Centre for Molecular Biosciences, University of Innsbruck , Austria.
Fritz EM; Department of Pharmacology and Toxicology, Centre for Molecular Biosciences, University of Innsbruck , Austria.
Obermair GJ; Institute of Physiology, Medical University Innsbruck , Innsbruck, Austria.; Division Physiology, Karl Landsteiner University of Health Sciences , Krems, Austria.
Striessnig J; Department of Pharmacology and Toxicology, Centre for Molecular Biosciences, University of Innsbruck , Austria.
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Źródło :
Channels (Austin, Tex.) [Channels (Austin)] 2021 Dec; Vol. 15 (1), pp. 38-52.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alternative Splicing*
Calcium Channels, L-Type*
Animals ; Exons ; HEK293 Cells ; Humans ; Mice
Czasopismo naukowe
Tytuł :
Alternative splicing regulation of cell-cycle genes by SPF45/SR140/CHERP complex controls cell proliferation.
Autorzy :
Martín E; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona 08003, Spain.; Universitat Pompeu Fabra (UPF), Barcelona 08003, Spain.
Vivori C; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona 08003, Spain.; Universitat Pompeu Fabra (UPF), Barcelona 08003, Spain.
Rogalska M; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona 08003, Spain.
Herrero-Vicente J; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona 08003, Spain.; Universitat Pompeu Fabra (UPF), Barcelona 08003, Spain.
Valcárcel J; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona 08003, Spain.; Universitat Pompeu Fabra (UPF), Barcelona 08003, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010 Barcelona, Spain.
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Źródło :
RNA (New York, N.Y.) [RNA] 2021 Dec; Vol. 27 (12), pp. 1557-1576. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alternative Splicing*
Gene Expression Regulation, Neoplastic*
Cell Cycle Proteins/*metabolism
DNA-Binding Proteins/*metabolism
Membrane Proteins/*metabolism
RNA Splicing Factors/*metabolism
RNA-Binding Proteins/*metabolism
Ribonucleoproteins/*metabolism
Uterine Cervical Neoplasms/*pathology
Apoptosis ; Cell Cycle Proteins/genetics ; Cell Proliferation ; DNA-Binding Proteins/genetics ; Female ; HeLa Cells ; Humans ; Membrane Proteins/genetics ; RNA Splicing Factors/genetics ; RNA-Binding Proteins/genetics ; Ribonucleoproteins/genetics ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Alternative splicing patterns of doublesex reveal a missing link between Nix and doublesex in the sex determination cascade of Aedes albopictus.
Autorzy :
Jin B; Department of Pathogen Biology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Zhao Y; Department of Pathogen Biology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Dong Y; Reproductive Medical Centre of Guangdong Women and Children Hospital, Guangzhou, 511442, China.
Liu P; Department of Pathogen Biology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Sun Y; Department of Pathogen Biology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Li X; Department of Pathogen Biology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Zhang X; Department of Pathogen Biology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Chen XG; Department of Pathogen Biology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Gu J; Department of Pathogen Biology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
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Źródło :
Insect science [Insect Sci] 2021 Dec; Vol. 28 (6), pp. 1601-1620. Date of Electronic Publication: 2020 Dec 02.
Typ publikacji :
Journal Article
MeSH Terms :
Aedes*/genetics
Alternative Splicing*
Sex Determination Processes*
Insect Proteins/*genetics
Animals ; DNA-Binding Proteins/genetics ; Female ; HeLa Cells ; Humans ; Male ; Mosquito Vectors ; Protein Isoforms
Czasopismo naukowe
Tytuł :
Comparative Transcriptome Analysis Revealed Two Alternative Splicing bHLHs Account for Flower Color Alteration in Chrysanthemum.
Autorzy :
Xiang L; College of Agriculture & Biotechnology, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.; Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.; The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.
Liu X; College of Agriculture & Biotechnology, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.; Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.; The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.
Shi Y; College of Agriculture & Biotechnology, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.; Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.; The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.
Li Y; College of Agriculture & Biotechnology, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.; Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.; The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.
Li W; Hunan Horticultural Research Institute, Changsha 410125, China.; Hunan Key Laboratory of Germplasm Innovation and Comprehensive Utilization of Landscape Flowers, Changsha 410125, China.
Li F; College of Agriculture & Biotechnology, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.; Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.
Chen K; College of Agriculture & Biotechnology, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.; Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.; The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zijingang Campus, Zhejiang University, Hangzhou 310058, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 25; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Alternative Splicing*
Color*
Transcriptome*
Basic Helix-Loop-Helix Transcription Factors/*metabolism
Chrysanthemum/*physiology
Flowers/*physiology
Plant Proteins/*metabolism
Basic Helix-Loop-Helix Transcription Factors/genetics ; Gene Expression Profiling ; Gene Expression Regulation, Plant ; Plant Proteins/genetics
Czasopismo naukowe
Tytuł :
The three as: Alternative splicing, alternative polyadenylation and their impact on apoptosis in immune function.
Autorzy :
Blake D; Immunology Graduate Group and the Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Lynch KW; Immunology Graduate Group and the Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
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Źródło :
Immunological reviews [Immunol Rev] 2021 Nov; Vol. 304 (1), pp. 30-50. Date of Electronic Publication: 2021 Aug 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Alternative Splicing*/genetics
Polyadenylation*
3' Untranslated Regions ; Apoptosis/genetics ; Humans ; Immunity ; RNA, Messenger
Czasopismo naukowe
Tytuł :
Wilms' tumor 1-associating protein complex regulates alternative splicing and polyadenylation at potential G-quadruplex-forming splice site sequences.
Autorzy :
Horiuchi K; Department of Protein-Protein Interaction Research, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan. Electronic address: .
Kawamura T; Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.
Hamakubo T; Department of Protein-Protein Interaction Research, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Nov; Vol. 297 (5), pp. 101248. Date of Electronic Publication: 2021 Sep 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alternative Splicing*
G-Quadruplexes*
Polyadenylation*
Cell Cycle Proteins/*metabolism
Multiprotein Complexes/*metabolism
RNA Splicing Factors/*metabolism
Cell Cycle Proteins/genetics ; CpG Islands ; HEK293 Cells ; Histone Acetyltransferases/biosynthesis ; Histone Acetyltransferases/genetics ; Human Umbilical Vein Endothelial Cells ; Humans ; Multiprotein Complexes/genetics ; RNA Splicing Factors/genetics ; RNA-Seq ; Ubiquitin-Protein Ligases/biosynthesis ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł :
The pattern of DNA methylation alteration, and its association with the changes of gene expression and alternative splicing during phosphate starvation in tomato.
Autorzy :
Tian P; Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong, 518060, China.; Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong, College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong, 518060, China.
Lin Z; Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong, 518060, China.
Lin D; Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong, 518060, China.; Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong, College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong, 518060, China.
Dong S; Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong, 518060, China.; Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong, College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong, 518060, China.
Huang J; Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong, 518060, China.
Huang T; Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong, 518060, China.
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Źródło :
The Plant journal : for cell and molecular biology [Plant J] 2021 Nov; Vol. 108 (3), pp. 841-858. Date of Electronic Publication: 2021 Sep 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alternative Splicing*
DNA Methylation*
Lycopersicon esculentum/*genetics
Cytosine/metabolism ; Epigenesis, Genetic ; Gene Expression Regulation, Plant ; Genome, Plant ; Lycopersicon esculentum/physiology ; Phosphates/metabolism ; Plant Proteins/genetics ; Seedlings/genetics
Czasopismo naukowe
Tytuł :
SRSF10: an atypical splicing regulator with critical roles in stress response, organ development, and viral replication.
Autorzy :
Shkreta L; RNA group, Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada J1E 4K8.
Delannoy A; RNA group, Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada J1E 4K8.
Salvetti A; INSERM, U1111, Centre International de Recherche en Infectiologie de Lyon (CIRI), CNRS UMR 5308, Lyon, France.
Chabot B; RNA group, Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada J1E 4K8.
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Źródło :
RNA (New York, N.Y.) [RNA] 2021 Nov; Vol. 27 (11), pp. 1302-1317. Date of Electronic Publication: 2021 Jul 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Alternative Splicing*
Organogenesis*
Stress, Physiological*
Virus Replication*
Cell Cycle Proteins/*metabolism
Repressor Proteins/*metabolism
Serine-Arginine Splicing Factors/*metabolism
Cell Cycle Proteins/genetics ; Humans ; Repressor Proteins/genetics ; Serine-Arginine Splicing Factors/genetics
Czasopismo naukowe
Tytuł :
KDM3A regulates alternative splicing of cell-cycle genes following DNA damage.
Autorzy :
Baker M; Department of Biochemistry and Molecular Biology, the Institute for Medical Research Israel Canada, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Petasny M; Department of Biochemistry and Molecular Biology, the Institute for Medical Research Israel Canada, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Taqatqa N; Department of Biochemistry and Molecular Biology, the Institute for Medical Research Israel Canada, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Bentata M; Department of Biochemistry and Molecular Biology, the Institute for Medical Research Israel Canada, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Kay G; Department of Biochemistry and Molecular Biology, the Institute for Medical Research Israel Canada, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Engal E; Department of Biochemistry and Molecular Biology, the Institute for Medical Research Israel Canada, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Nevo Y; Department of Biochemistry and Molecular Biology, the Institute for Medical Research Israel Canada, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Siam A; Department of Biochemistry and Molecular Biology, the Institute for Medical Research Israel Canada, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Dahan S; Department of Biochemistry and Molecular Biology, the Institute for Medical Research Israel Canada, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Salton M; Department of Biochemistry and Molecular Biology, the Institute for Medical Research Israel Canada, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
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Źródło :
RNA (New York, N.Y.) [RNA] 2021 Nov; Vol. 27 (11), pp. 1353-1362. Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alternative Splicing*
Gene Expression Regulation, Neoplastic*
Acetyltransferases/*metabolism
Breast Neoplasms/*pathology
DNA-Binding Proteins/*metabolism
Jumonji Domain-Containing Histone Demethylases/*metabolism
Serine-Arginine Splicing Factors/*metabolism
Transcription Factors/*metabolism
Acetyltransferases/genetics ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; DNA Damage ; DNA-Binding Proteins/genetics ; Humans ; Jumonji Domain-Containing Histone Demethylases/genetics ; MCF-7 Cells ; Phosphorylation ; Protein Binding ; RNA Precursors/genetics ; RNA Precursors/metabolism ; Serine-Arginine Splicing Factors/genetics ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Impact of alternative splicing on mechanisms of resistance to anticancer drugs.
Autorzy :
Reviejo M; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Institute for Biomedical Research of Salamanca (IBSAL), Salamanca 37007, Spain; Center for the Study of Liver and Gastrointestinal Diseases (CIBERehd), Carlos III National Institute of Health, Madrid 28029, Spain.
Soto M; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Institute for Biomedical Research of Salamanca (IBSAL), Salamanca 37007, Spain.
Lozano E; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Institute for Biomedical Research of Salamanca (IBSAL), Salamanca 37007, Spain; Center for the Study of Liver and Gastrointestinal Diseases (CIBERehd), Carlos III National Institute of Health, Madrid 28029, Spain.
Asensio M; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Institute for Biomedical Research of Salamanca (IBSAL), Salamanca 37007, Spain; Center for the Study of Liver and Gastrointestinal Diseases (CIBERehd), Carlos III National Institute of Health, Madrid 28029, Spain.
Martínez-Augustin O; Department of Biochemistry and Molecular Biology II, University of Granada, Spain; Center for the Study of Liver and Gastrointestinal Diseases (CIBERehd), Carlos III National Institute of Health, Madrid 28029, Spain.
Sánchez de Medina F; Department of Pharmacology, University of Granada, Spain; Center for the Study of Liver and Gastrointestinal Diseases (CIBERehd), Carlos III National Institute of Health, Madrid 28029, Spain.
Marin JJG; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Institute for Biomedical Research of Salamanca (IBSAL), Salamanca 37007, Spain; Center for the Study of Liver and Gastrointestinal Diseases (CIBERehd), Carlos III National Institute of Health, Madrid 28029, Spain. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2021 Nov; Vol. 193, pp. 114810. Date of Electronic Publication: 2021 Oct 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Alternative Splicing*
Antineoplastic Agents/*pharmacology
Drug Resistance, Neoplasm/*genetics
Neoplasms/*drug therapy
Neoplasms/*metabolism
Animals ; Gene Expression Regulation, Neoplastic ; Humans
Czasopismo naukowe
Tytuł :
Experimental Design for Time-Series RNA-Seq Analysis of Gene Expression and Alternative Splicing.
Autorzy :
Tzioutziou NA; Division of Plant Sciences, University of Dundee at the James Hutton Institute, Dundee, UK.
James AB; Institute of Molecular, Cell, and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Guo W; Division of Plant Sciences, University of Dundee at the James Hutton Institute, Dundee, UK.
Calixto CPG; Division of Plant Sciences, University of Dundee at the James Hutton Institute, Dundee, UK.
Zhang R; Information and Computational Sciences, The James Hutton Institute, Dundee, UK.
Nimmo HG; Institute of Molecular, Cell, and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Brown JWS; Division of Plant Sciences, University of Dundee at the James Hutton Institute, Dundee, UK. .; Cell and Molecular Sciences, The James Hutton Institute, Dundee, UK. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2398, pp. 173-188.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alternative Splicing*
Gene Expression Profiling ; RNA-Seq ; Research Design ; Sequence Analysis, RNA ; Transcriptome
Czasopismo naukowe
Tytuł :
CD44: A Multifunctional Mediator of Cancer Progression.
Autorzy :
Hassn Mesrati M; Nanobiotechnology Research Group, Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.
Syafruddin SE; UKM Medical Molecular Biology Institute (UMBI), Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia.
Mohtar MA; UKM Medical Molecular Biology Institute (UMBI), Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia.
Syahir A; Nanobiotechnology Research Group, Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.; UPM-MAKNA Cancer Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400 UPM, Selangor, Malaysia.
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Źródło :
Biomolecules [Biomolecules] 2021 Dec 09; Vol. 11 (12). Date of Electronic Publication: 2021 Dec 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Alternative Splicing*
Hyaluronan Receptors/*genetics
Neoplasms/*pathology
Disease Progression ; Epithelial-Mesenchymal Transition ; Gene Expression Regulation, Neoplastic ; Humans ; Hyaluronan Receptors/metabolism ; Neoplasm Grading ; Neoplasm Staging ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplastic Stem Cells/metabolism ; Prognosis ; Survival Analysis
Czasopismo naukowe
Tytuł :
PCBP1 regulates the transcription and alternative splicing of metastasis‑related genes and pathways in hepatocellular carcinoma.
Autorzy :
Huang S; Departments of Hepatobiliary Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.
Luo K; Departments of Hepatobiliary Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.
Jiang L; Departments of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.
Zhang XD; Departments of Hepatobiliary Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.
Lv YH; Departments of Hepatobiliary Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.
Li RF; Departments of Hepatobiliary Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China. .
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Źródło :
Scientific reports [Sci Rep] 2021 Dec 02; Vol. 11 (1), pp. 23356. Date of Electronic Publication: 2021 Dec 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alternative Splicing*
Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*metabolism
Carcinoma, Hepatocellular/*pathology
DNA-Binding Proteins/*metabolism
Liver Neoplasms/*pathology
RNA Splicing Factors/*metabolism
RNA-Binding Proteins/*metabolism
Biomarkers, Tumor/genetics ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/metabolism ; DNA-Binding Proteins/genetics ; Gene Expression Profiling ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism ; Neoplasm Metastasis ; Prognosis ; RNA Splicing Factors/genetics ; RNA-Binding Proteins/genetics ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Dyskerin: an essential pseudouridine synthase with multifaceted roles in ribosome biogenesis, splicing, and telomere maintenance.
Autorzy :
Garus A; Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, H3A 0C7, Canada.; Jewish General Hospital, Lady Davis Institute, Montreal, Quebec, H3T 1E2, Canada.
Autexier C; Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, H3A 0C7, Canada.; Jewish General Hospital, Lady Davis Institute, Montreal, Quebec, H3T 1E2, Canada.
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Źródło :
RNA (New York, N.Y.) [RNA] 2021 Dec; Vol. 27 (12), pp. 1441-1458. Date of Electronic Publication: 2021 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Alternative Splicing*
Mutation*
RNA Processing, Post-Transcriptional*
Cell Cycle Proteins/*metabolism
Intramolecular Transferases/*metabolism
Nuclear Proteins/*metabolism
Ribosomes/*metabolism
Telomere/*physiology
Cell Cycle Proteins/genetics ; Dyskeratosis Congenita ; Humans ; Intramolecular Transferases/genetics ; Nuclear Proteins/genetics
Czasopismo naukowe
Tytuł :
Molecular Determinants and Specificity of mRNA with Alternatively-Spliced UPF1 Isoforms, Influenced by an Insertion in the 'Regulatory Loop'.
Autorzy :
Padariya M; International Centre for Cancer Vaccine Science, University of Gdansk, ul. Kładki 24, 80-822 Gdansk, Poland.
Fahraeus R; International Centre for Cancer Vaccine Science, University of Gdansk, ul. Kładki 24, 80-822 Gdansk, Poland.; Inserm UMRS1131, Institut de Génétique Moléculaire, Université Paris 7, Hôpital St. Louis, F-75010 Paris, France.; Department of Medical Biosciences, Umeå University, Building 6M, 90185 Umeå, Sweden.; Regional Centre for Applied Molecular Oncology (RECAMO), Masaryk Memorial Cancer Institute, Zlutykopec 7, 65653 Brno, Czech Republic.
Hupp T; International Centre for Cancer Vaccine Science, University of Gdansk, ul. Kładki 24, 80-822 Gdansk, Poland.; Institute of Genetics and Cancer, University of Edinburgh, Edinburgh EH4 2XR, UK.
Kalathiya U; International Centre for Cancer Vaccine Science, University of Gdansk, ul. Kładki 24, 80-822 Gdansk, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 25; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Alternative Splicing*
Gene Expression Regulation*
Nonsense Mediated mRNA Decay*
RNA Helicases/*metabolism
RNA, Messenger/*metabolism
Trans-Activators/*metabolism
Humans ; Phosphorylation ; Protein Binding ; Protein Isoforms ; RNA Helicases/genetics ; RNA, Messenger/genetics ; Trans-Activators/genetics
Czasopismo naukowe
Tytuł :
Alternative splicing level related to intron size and organism complexity.
Autorzy :
Yang P; Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
Wang D; Sino-Danish College, University of Chinese Academy of Sciences, Beijing, China.
Kang L; Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China. .
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Źródło :
BMC genomics [BMC Genomics] 2021 Nov 25; Vol. 22 (1), pp. 853. Date of Electronic Publication: 2021 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Alternative Splicing*
Eukaryota*/genetics
Genome ; Introns/genetics ; RNA Splicing ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Splice-Variant Knock-Out of TGFβ Receptors Perturbates the Proteome of Ovarian Carcinoma Cells.
Autorzy :
Jacobs Catane L; Institute of Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
Moshel O; Core Research Facility, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
Smith Y; Genomic Data Analysis Unit, The Hebrew University of Jerusalem-Hadassah Medical School, P.O. Box 12272, Jerusalem 91120, Israel.
Davidson B; Department of Pathology, Oslo University Hospital, Norwegian Radium Hospital, N-0310 Oslo, Norway.; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, N-0316 Oslo, Norway.
Reich R; Institute of Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 23; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 23.
Typ publikacji :
Journal Article
MeSH Terms :
Alternative Splicing*
Ovarian Neoplasms/*metabolism
Proteomics/*methods
Receptor, Transforming Growth Factor-beta Type I/*genetics
Receptor, Transforming Growth Factor-beta Type II/*genetics
Cell Line, Tumor ; Cell Movement ; Epithelial-Mesenchymal Transition ; Female ; Gene Expression Regulation, Neoplastic ; Gene Knockout Techniques ; Humans ; Nuclear Proteins/metabolism ; Ovarian Neoplasms/genetics ; Protein Interaction Maps ; Proto-Oncogene Proteins c-met/metabolism ; RNA, Long Noncoding/genetics ; Reactive Oxygen Species/metabolism ; Snail Family Transcription Factors/metabolism ; Twist-Related Protein 1/metabolism
Czasopismo naukowe
Tytuł :
In1-Ghrelin Splicing Variant as a Key Element in the Pathophysiological Association Between Obesity and Prostate Cancer.
Autorzy :
Jiménez-Vacas JM; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Cordoba, Spain.
Montero-Hidalgo AJ; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Cordoba, Spain.
Gómez-Gómez E; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; Urology Service, HURS/IMIBIC, Cordoba, Spain.
Fuentes-Fayos AC; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Cordoba, Spain.
Ruiz-Pino F; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Cordoba, Spain.
Guler I; Leuven Biostatistics and Statistical Bioinformatics Centre (L-BioStat), Katholiek Universiteit (KU) Leuven, University of Leuven, Leuven, Belgium.
Camargo A; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Cordoba, Spain.; Lipids and Atherosclerosis Unit, Internal Medicine Unit, Reina Sofia University Hospital, Cordoba, Spain.
Anglada FJ; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; Urology Service, HURS/IMIBIC, Cordoba, Spain.
Carrasco-Valiente J; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; Urology Service, HURS/IMIBIC, Cordoba, Spain.
Tena-Sempere M; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Cordoba, Spain.
Sarmento-Cabral A; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Cordoba, Spain.
Castaño JP; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Cordoba, Spain.
Gahete MD; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Cordoba, Spain.
Luque RM; Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Cordoba, Spain.; Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain.; Reina Sofia University Hospital (HURS), Cordoba, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Cordoba, Spain.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2021 Nov 19; Vol. 106 (12), pp. e4956-e4968.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alternative Splicing*
Biomarkers, Tumor/*analysis
Diabetes Mellitus, Type 2/*physiopathology
Ghrelin/*genetics
Obesity/*physiopathology
Prostatic Neoplasms/*epidemiology
Aged ; Blood Glucose/analysis ; Body Mass Index ; Case-Control Studies ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Prognosis ; Prostate-Specific Antigen/blood ; Prostatic Neoplasms/blood ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/pathology ; Protein Isoforms ; ROC Curve ; Retrospective Studies ; Spain/epidemiology
Czasopismo naukowe

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