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Wyszukujesz frazę ""Alveolar Epithelial Cells"" wg kryterium: Temat


Tytuł:
Glycogen Synthase Kinase-3 Inhibition by CHIR99021 Promotes Alveolar Epithelial Cell Proliferation and Lung Regeneration in the Lipopolysaccharide-Induced Acute Lung Injury Mouse Model.
Autorzy:
Fernandes R; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4806-909 Braga, Portugal.
Barbosa-Matos C; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4806-909 Braga, Portugal.
Borges-Pereira C; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4806-909 Braga, Portugal.
Carvalho ALRT; Department of Internal Medicine, São João Universitary Hospital Center, 4200-319 Porto, Portugal.; Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
Costa S; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4806-909 Braga, Portugal.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 20; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 20.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*
Acute Lung Injury*/chemically induced
Acute Lung Injury*/pathology
Pyridines*
Pyrimidines*
Animals ; Mice ; Lipopolysaccharides/pharmacology ; Glycogen Synthase Kinase 3 ; Lung/pathology ; Cell Proliferation
Czasopismo naukowe
Tytuł:
Pneumococcus downregulates the molecular weight of the extracellular domain of the epidermal growth factor receptor of alveolar epithelial cells.
Autorzy:
Isono T; Division of Microbiology and Infectious Diseases, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Hirayama S; Division of Microbiology and Infectious Diseases, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Domon H; Division of Microbiology and Infectious Diseases, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.; Center for Advanced Oral Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Terao Y; Division of Microbiology and Infectious Diseases, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.; Center for Advanced Oral Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
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Źródło:
Microbiology and immunology [Microbiol Immunol] 2024 Jan; Vol. 68 (1), pp. 23-26. Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*/metabolism
Streptococcus pneumoniae*
Molecular Weight ; ErbB Receptors ; Cell Proliferation ; Epithelial Cells/metabolism
Czasopismo naukowe
Tytuł:
Real-Time Quantification of Nanoplastics-Induced Oxidative Stress in Stretching Alveolar Cells.
Autorzy:
Zhao Y; College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
Fan WT; College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
Jin KQ; College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
Yan J; College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
Qi YT; College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
Huang WH; College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
Liu YL; College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
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Źródło:
ACS nano [ACS Nano] 2024 Feb 27; Vol. 18 (8), pp. 6176-6185. Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*
Microplastics*
Pulmonary Alveoli ; Lung ; Oxidative Stress
Czasopismo naukowe
Tytuł:
Increased CTGF expression in alveolar epithelial cells by cyclic mechanical stretch: Its mechanism and the therapeutic effect of pirfenidone.
Autorzy:
Aoyama J; Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, 113-8603 Tokyo, Japan.
Saito Y; Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, 113-8603 Tokyo, Japan. Electronic address: .
Matsuda K; Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, 113-8603 Tokyo, Japan.
Tanaka T; Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, 113-8603 Tokyo, Japan.
Kamio K; Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, 113-8603 Tokyo, Japan.
Gemma A; Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, 113-8603 Tokyo, Japan.
Seike M; Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, 113-8603 Tokyo, Japan.
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Źródło:
Respiratory physiology & neurobiology [Respir Physiol Neurobiol] 2023 Nov; Vol. 317, pp. 104142. Date of Electronic Publication: 2023 Aug 23.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*
Lung Injury*
Humans ; Animals ; Mice ; Connective Tissue Growth Factor ; Cytokines ; Mitogen-Activated Protein Kinase Kinases
Czasopismo naukowe
Tytuł:
Epoxyeicosatrienoic acids alleviate alveolar epithelial cell senescence by inhibiting mitophagy through NOX4/Nrf2 pathway.
Autorzy:
Hong JR; Department of Geriatrics, Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410078, China; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Zhang CY; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Zhong WJ; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Yang HH; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Xiong JB; Department of Emergency, Xiangya Hospital, Central South University, Changsha, Hunan 410078, China.
Deng P; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Yang NS; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Chen H; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Jin L; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Guan CX; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Duan JX; Department of Geriatrics, Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410078, China; National Clinical Research Center of Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410078, China. Electronic address: .
Zhou Y; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Dec 31; Vol. 169, pp. 115937. Date of Electronic Publication: 2023 Nov 25.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*/metabolism
Lung Diseases*
Mice ; Animals ; Mitophagy ; NF-E2-Related Factor 2/metabolism ; Reactive Oxygen Species/metabolism ; Cytochrome P-450 Enzyme System/metabolism ; Cellular Senescence
Czasopismo naukowe
Tytuł:
Dexamethasone restores TNFα-induced epithelial barrier dysfunction in primary rat alveolar epithelial cells.
Autorzy:
Kutsuzawa N; Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Ito Y; Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Kagawa S; Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Kohno C; Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Takiguchi H; Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Asano K; Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
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Źródło:
PloS one [PLoS One] 2023 Dec 27; Vol. 18 (12), pp. e0295684. Date of Electronic Publication: 2023 Dec 27 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*/metabolism
Respiratory Distress Syndrome*
Rats ; Animals ; Tumor Necrosis Factor-alpha ; Rats, Sprague-Dawley ; Tight Junction Proteins/metabolism ; Dexamethasone/pharmacology ; Epithelial Cells/metabolism
Czasopismo naukowe
Tytuł:
Fusobacterium nucleatum putatively affects the alveoli by disrupting the alveolar epithelial cell tight junction, enlarging the alveolar space, and increasing paracellular permeability.
Autorzy:
Karahashi Y; Department of Periodontology, Nihon University School of Dentistry, Tokyo, 101-8310, Japan; Department of Microbiology and Immunology, Nihon University School of Dentistry, Tokyo, 101-8310, Japan.
Cueno ME; Department of Microbiology and Immunology, Nihon University School of Dentistry, Tokyo, 101-8310, Japan.
Kamio N; Department of Microbiology and Immunology, Nihon University School of Dentistry, Tokyo, 101-8310, Japan.
Takahashi Y; Department of Microbiology and Immunology, Nihon University School of Dentistry, Tokyo, 101-8310, Japan.
Takeshita I; Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, 173-8610, Japan.
Soda K; Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, 173-8610, Japan.
Maruoka S; Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, 173-8610, Japan.
Gon Y; Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, 173-8610, Japan.
Sato S; Department of Periodontology, Nihon University School of Dentistry, Tokyo, 101-8310, Japan.
Imai K; Department of Microbiology and Immunology, Nihon University School of Dentistry, Tokyo, 101-8310, Japan. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Nov 19; Vol. 682, pp. 216-222. Date of Electronic Publication: 2023 Oct 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alveolar Epithelial Cells*
Tight Junctions*/metabolism
Mice ; Animals ; Humans ; Fusobacterium nucleatum ; Lung ; Permeability ; Epithelial Cells/metabolism
Czasopismo naukowe
Tytuł:
"Stuck in the Middle with You": intermediate cell states are not always in transition.
Autorzy:
Sucre JM; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.
McCall AS; Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Kropski JA; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.; Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
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Źródło:
The Journal of clinical investigation [J Clin Invest] 2023 Nov 15; Vol. 133 (22). Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Alveolar Epithelial Cells*/metabolism
Lung*
Cells, Cultured ; Epithelial Cells ; Biomarkers/metabolism
Czasopismo naukowe
Tytuł:
Inhibition of METTL3 alleviated LPS-induced alveolar epithelial cell apoptosis and acute lung injury via restoring neprilysin expression.
Autorzy:
Jia J; Department of Emergency Medicine, The Second Xiangya Hospital of Central South University, Emergency and Difficult Diseases Institute of Central South University, Changsha, Hunan, PR China.
Yuan Y; Department of Respiratory Medicine, Hunan Center for Evidence-Based Medicine, Research Unit of Respiratory Diseases, The Second Xiangya Hospital of Central South University, Changsha, PR China.
He Y; Department of Respiratory Medicine, Hunan Center for Evidence-Based Medicine, Research Unit of Respiratory Diseases, The Second Xiangya Hospital of Central South University, Changsha, PR China.
Wasti B; Department of Respiratory Medicine, Hunan Center for Evidence-Based Medicine, Research Unit of Respiratory Diseases, The Second Xiangya Hospital of Central South University, Changsha, PR China.
Duan W; Department of Respiratory Medicine, Hunan Center for Evidence-Based Medicine, Research Unit of Respiratory Diseases, The Second Xiangya Hospital of Central South University, Changsha, PR China.
Chen Z; Department of Respiratory Medicine, Hunan Center for Evidence-Based Medicine, Research Unit of Respiratory Diseases, The Second Xiangya Hospital of Central South University, Changsha, PR China.
Li D; Department of Respiratory Medicine, Hunan Center for Evidence-Based Medicine, Research Unit of Respiratory Diseases, The Second Xiangya Hospital of Central South University, Changsha, PR China.
Sun W; Department of General Medicine, West China Hospital, Sichuan University, Chengdu, PR China.
Zeng Q; Longshan County People's Hospital, PR China.
Ma L; Department of Respiratory and Critical Care Medicine, The Affiliated Hospital of Guilin Medical University, Guangxi, PR China.
Zhang X; Department of Respiratory Medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, PR China.
Liu S; Department of Respiratory Medicine, Hunan Center for Evidence-Based Medicine, Research Unit of Respiratory Diseases, The Second Xiangya Hospital of Central South University, Changsha, PR China.
Zhang D; Department of Emergency Medicine, The Second Xiangya Hospital of Central South University, Emergency and Difficult Diseases Institute of Central South University, Changsha, Hunan, PR China.
Liu L; Department of Respiratory and Critical Care Medicine, Guilin Hospital of the Second Xiangya Hospital of Central South University, Guilin, Guangxi, PR China.
Liu Q; Department of Respiratory and Critical Care Medicine, Guilin Hospital of the Second Xiangya Hospital of Central South University, Guilin, Guangxi, PR China.
Liang H; Department of Thoracic Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan, PR China; Department of Thoracic Surgery, Guilin Hospital of the Second Xiangya Hospital of Central South University, Guilin, Guangxi, PR China.
Wang G; Department of Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, PR China.
Xiang X; Department of Emergency Medicine, The Second Xiangya Hospital of Central South University, Emergency and Difficult Diseases Institute of Central South University, Changsha, Hunan, PR China; Department of Respiratory and Critical Care Medicine, Guilin Hospital of the Second Xiangya Hospital of Central South University, Guilin, Guangxi, PR China. Electronic address: .
Xiao B; Department of Emergency Medicine, The Second Xiangya Hospital of Central South University, Emergency and Difficult Diseases Institute of Central South University, Changsha, Hunan, PR China; Department of Respiratory and Critical Care Medicine, Guilin Hospital of the Second Xiangya Hospital of Central South University, Guilin, Guangxi, PR China. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2023 Nov 15; Vol. 333, pp. 122148. Date of Electronic Publication: 2023 Oct 05.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury*/metabolism
Alveolar Epithelial Cells*/metabolism
Animals ; Mice ; Apoptosis ; In Situ Hybridization, Fluorescence ; Lipopolysaccharides/pharmacology ; Lung/metabolism ; Neprilysin
Czasopismo naukowe
Tytuł:
[Leptin-mediated ERK Signaling Pathway Promotes the Transformation 
of Rat Alveolar Type II Epithelial Cells Induced by Yunnan Tin Mine Dust].
Autorzy:
Hu X; Department of Pathology, The First Affliated Hospital of Kunming Medical University, Kunming 650031, China.
Yan C; Basic Medicine of Kunming Medical University School of Basic Medicine, Kunming 650500, China.
Zhang Y; Department of Pathology, The First Affliated Hospital of Kunming Medical University, Kunming 650031, China.
Li G; Department of Pathology, The First Affliated Hospital of Kunming Medical University, Kunming 650031, China.
Zhou Z; Department of Pathology, The Third People's Hospital of Yunnan Province, Kunming 650011, China.
Ruan Y; Basic Medicine of Kunming Medical University School of Basic Medicine, Kunming 650500, China.
Liu S; Department of Pathology, The First Affliated Hospital of Kunming Medical University, Kunming 650031, China.
Bian L; Department of Pathology, The First Affliated Hospital of Kunming Medical University, Kunming 650031, China.
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Źródło:
Zhongguo fei ai za zhi = Chinese journal of lung cancer [Zhongguo Fei Ai Za Zhi] 2023 Oct 20; Vol. 26 (10), pp. 732-740.
Typ publikacji:
English Abstract; Journal Article
MeSH Terms:
Alveolar Epithelial Cells*/pathology
Lung Neoplasms*/pathology
Rats ; Animals ; Dust ; Tin/adverse effects ; Leptin/adverse effects ; Receptors, Leptin ; China ; Signal Transduction ; Epithelial Cells/pathology ; Mitogen-Activated Protein Kinase Kinases/adverse effects
Czasopismo naukowe
Tytuł:
Molecular markers of type II alveolar epithelial cells in acute lung injury by bioinformatics analysis.
Autorzy:
Yang X; Emergency Department, The First Hospital of China Medical University, No.155 of North Street Nanjing, Heping District, Shenyang City, 110001, Liaoning Province, China.
Wang J; Emergency Department, The First Hospital of China Medical University, No.155 of North Street Nanjing, Heping District, Shenyang City, 110001, Liaoning Province, China.
Liu W; Emergency Department, The First Hospital of China Medical University, No.155 of North Street Nanjing, Heping District, Shenyang City, 110001, Liaoning Province, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 18; Vol. 13 (1), pp. 17797. Date of Electronic Publication: 2023 Oct 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alveolar Epithelial Cells*
Computational Biology*/methods
Animals ; Mice ; Biomarkers ; Cytokines ; Chemokines ; Gene Expression Profiling/methods
Czasopismo naukowe
Tytuł:
Oxidative stress and activation of H2A.X in lung alveolar epithelial cells (A549) by nanoparticulate carbon black.
Autorzy:
Niechoda A; Department of Pharmacology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland.
Roslan J; Department of Pharmacology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland.
Maciorowska K; Department of Pharmacology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland.
Rosłan M; Department of Pharmacology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland.
Ejsmont K; Department of Pharmacology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland.
Holownia A; Department of Pharmacology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland. Electronic address: .
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Źródło:
Respiratory physiology & neurobiology [Respir Physiol Neurobiol] 2023 Oct; Vol. 316, pp. 104140. Date of Electronic Publication: 2023 Aug 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alveolar Epithelial Cells*
Histones*
Soot/toxicity ; Soot/metabolism ; Lung/metabolism ; Oxidative Stress ; RNA, Messenger/metabolism ; DNA Damage ; Epithelial Cells/metabolism
Czasopismo naukowe
Tytuł:
EETs alleviate alveolar epithelial cell senescence by inhibiting endoplasmic reticulum stress through the Trim25/Keap1/Nrf2 axis.
Autorzy:
Zhang CY; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan, 410078, China.
Zhong WJ; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan, 410078, China.
Liu YB; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan, 410078, China.
Duan JX; Department of Geriatrics, Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, 410078, China.
Jiang N; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan, 410078, China.
Yang HH; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan, 410078, China.
Ma SC; NHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, 750004, China; The School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, 750004, China.
Jin L; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan, 410078, China.
Hong JR; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan, 410078, China.
Zhou Y; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan, 410078, China. Electronic address: .
Guan CX; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan, 410078, China. Electronic address: .
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Źródło:
Redox biology [Redox Biol] 2023 Jul; Vol. 63, pp. 102765. Date of Electronic Publication: 2023 May 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alveolar Epithelial Cells*/drug effects
Alveolar Epithelial Cells*/physiology
Eicosanoids*/pharmacology
Endoplasmic Reticulum Stress*/drug effects
NF-E2-Related Factor 2*/genetics
Cellular Senescence*/drug effects
Animals ; Mice ; Kelch-Like ECH-Associated Protein 1 ; Pulmonary Fibrosis
Czasopismo naukowe
Tytuł:
Mitochondrial integrated stress response controls lung epithelial cell fate.
Autorzy:
Han S; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA. .
Lee M; Department of Life Science, Dongguk University-Seoul, Goyang-si, Republic of Korea.
Shin Y; Department of Life Science, Dongguk University-Seoul, Goyang-si, Republic of Korea.
Giovanni R; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Chakrabarty RP; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Herrerias MM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Dada LA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Flozak AS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Reyfman PA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Khuder B; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Reczek CR; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Gao L; Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, Seville, Spain.
Lopéz-Barneo J; Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, Seville, Spain.
Gottardi CJ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Budinger GRS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Chandel NS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA. .; Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA. .
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Źródło:
Nature [Nature] 2023 Aug; Vol. 620 (7975), pp. 890-897. Date of Electronic Publication: 2023 Aug 09.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*/cytology
Alveolar Epithelial Cells*/metabolism
Alveolar Epithelial Cells*/pathology
Cell Differentiation*
Cell Lineage*
Lung*/cytology
Lung*/metabolism
Lung*/pathology
Mitochondria*/enzymology
Mitochondria*/metabolism
Stress, Physiological*
Animals ; Mice ; NAD/metabolism ; NADH Dehydrogenase/metabolism ; Protons ; RNA-Seq ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Single-Cell Gene Expression Analysis
Czasopismo naukowe
Tytuł:
AMPK activation improves recovery from pneumonia-induced lung injury via reduction of er-stress and apoptosis in alveolar epithelial cells.
Autorzy:
Becker E Jr; Division of Pulmonary, Allergy and Critical Care, Department of Medicine, University of Alabama at Birmingham, 901 19th St. South BMRII 406, Birmingham, AL, 35294-0012, USA.
Husain M; Division of Pulmonary, Allergy and Critical Care, Department of Medicine, University of Alabama at Birmingham, 901 19th St. South BMRII 406, Birmingham, AL, 35294-0012, USA.
Bone N; Division of Pulmonary, Allergy and Critical Care, Department of Medicine, University of Alabama at Birmingham, 901 19th St. South BMRII 406, Birmingham, AL, 35294-0012, USA.
Smith S; Division of Pulmonary, Allergy and Critical Care, Department of Medicine, University of Alabama at Birmingham, 901 19th St. South BMRII 406, Birmingham, AL, 35294-0012, USA.
Morris P; Division of Pulmonary, Allergy and Critical Care, Department of Medicine, University of Alabama at Birmingham, 901 19th St. South BMRII 406, Birmingham, AL, 35294-0012, USA.
Zmijewski JW; Division of Pulmonary, Allergy and Critical Care, Department of Medicine, University of Alabama at Birmingham, 901 19th St. South BMRII 406, Birmingham, AL, 35294-0012, USA. .
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Źródło:
Respiratory research [Respir Res] 2023 Jul 12; Vol. 24 (1), pp. 185. Date of Electronic Publication: 2023 Jul 12.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*
Lung Injury*/drug therapy
Animals ; Mice ; AMP-Activated Protein Kinases ; Glycogen Synthase Kinase 3 beta ; Apoptosis
SCR Disease Name:
Hay-Wells syndrome
Czasopismo naukowe
Tytuł:
p53 governs an AT1 differentiation programme in lung cancer suppression.
Autorzy:
Kaiser AM; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Gatto A; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Hanson KJ; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
Zhao RL; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Raj N; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Ozawa MG; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Seoane JA; Cancer Computational Biology Group, Vall d'Hebron Institute of Oncology, Barcelona, Spain.
Bieging-Rolett KT; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Wang M; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Li I; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA.
Trope WL; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Liou DZ; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Shrager JB; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Plevritis SK; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA.
Newman AM; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA.
Van Rechem C; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Attardi LD; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA. .; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. .
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Źródło:
Nature [Nature] 2023 Jul; Vol. 619 (7971), pp. 851-859. Date of Electronic Publication: 2023 Jul 19.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*/cytology
Alveolar Epithelial Cells*/metabolism
Alveolar Epithelial Cells*/pathology
Cell Differentiation*
Lung*/cytology
Lung*/metabolism
Lung*/pathology
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
Lung Neoplasms*/prevention & control
Tumor Suppressor Protein p53*/deficiency
Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Animals ; Mice ; Mice, Knockout ; Alleles ; Gene Expression Profiling ; Chromatin Assembly and Disassembly ; DNA/metabolism ; Lung Injury/genetics ; Lung Injury/metabolism ; Lung Injury/pathology ; Disease Progression ; Cell Lineage ; Regeneration ; Cell Self Renewal
Czasopismo naukowe
Tytuł:
Lung repair empowered by exogenous cells taking residence.
Autorzy:
Xu L; Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Sun X; Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: .
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Źródło:
Cell stem cell [Cell Stem Cell] 2023 Sep 07; Vol. 30 (9), pp. 1127-1129.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Alveolar Epithelial Cells*
Pluripotent Stem Cells*
Animals ; Mice ; Stem Cell Transplantation
Czasopismo naukowe
Tytuł:
PAI-1 Regulation of p53 Expression and Senescence in Type II Alveolar Epithelial Cells.
Autorzy:
Rana T; Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Jiang C; Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Banerjee S; Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Yi N; Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Zmijewski JW; Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Liu G; Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Liu RM; Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
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Źródło:
Cells [Cells] 2023 Aug 05; Vol. 12 (15). Date of Electronic Publication: 2023 Aug 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Alveolar Epithelial Cells*/metabolism
Idiopathic Pulmonary Fibrosis*/metabolism
Plasminogen Activator Inhibitor 1*/metabolism
Tumor Suppressor Protein p53*/metabolism
Animals ; Humans ; Mice ; Proteasome Endopeptidase Complex/metabolism
Czasopismo naukowe
Tytuł:
Enhanced glycolysis-mediated energy production in alveolar stem cells is required for alveolar regeneration.
Autorzy:
Wang Z; National Institute of Biological Sciences, Beijing, China; Graduate School of Peking Union Medical College, Beijing, China.
Wei D; National Institute of Biological Sciences, Beijing, China; Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate Program, Peking University, Beijing, China.
Bin E; National Institute of Biological Sciences, Beijing, China.
Li J; National Institute of Biological Sciences, Beijing, China.
Jiang K; National Institute of Biological Sciences, Beijing, China.
Lv T; Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.
Mao X; National Institute of Biological Sciences, Beijing, China; Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China.
Wang F; National Institute of Biological Sciences, Beijing, China; Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China.
Dai H; Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.
Tang N; National Institute of Biological Sciences, Beijing, China; Graduate School of Peking Union Medical College, Beijing, China; Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China. Electronic address: .
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Źródło:
Cell stem cell [Cell Stem Cell] 2023 Aug 03; Vol. 30 (8), pp. 1028-1042.e7.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
AMP-Activated Protein Kinases*/metabolism
Alveolar Epithelial Cells*/metabolism
Mice ; Animals ; Lung ; Stem Cells ; Cell Differentiation ; Glycolysis
Czasopismo naukowe
Tytuł:
The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis.
Autorzy:
Lee SY; Department of Biochemistry and Molecular Biology, Severance Medical Research Institute, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Korea.
Park SY; Department of Biochemistry and Molecular Biology, Severance Medical Research Institute, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Korea.
Lee SH; Department of Biochemistry and Molecular Biology, Severance Medical Research Institute, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Korea.
Kim H; Department of Biochemistry and Molecular Biology, Severance Medical Research Institute, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Korea.
Kwon JH; Department of Biochemistry and Molecular Biology, Severance Medical Research Institute, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Korea.
Yoo JY; Department of Biomedical Laboratory Science, Yonsei University Mirae Campus, Wonju, South Korea.
Kim K; Department of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Park MS; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, 03722, Korea.
Lee CG; Molecular Microbiology and Immunology, Brown University, Providence, RI, USA.; Department of Internal Medicine, Hanyang University, Seoul, 04763, Korea.
Elias JA; Molecular Microbiology and Immunology, Brown University, Providence, RI, USA.
Sohn MH; Department of Pediatrics and Institute of Allergy, Severance Medical Research Institute, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul, 03722, Korea.
Shim HS; Department of Pathology, Yonsei University College of Medicine, Seoul, 03722, Korea. .
Yoon HG; Department of Biochemistry and Molecular Biology, Severance Medical Research Institute, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Korea. .
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Źródło:
Experimental & molecular medicine [Exp Mol Med] 2023 Aug; Vol. 55 (8), pp. 1795-1805. Date of Electronic Publication: 2023 Aug 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alveolar Epithelial Cells*
Idiopathic Pulmonary Fibrosis*/genetics
Ubiquitin Thiolesterase*/metabolism
Animals ; Mice ; Chemokine CCL2/genetics ; Deubiquitinating Enzymes ; Lung ; Humans ; E1A-Associated p300 Protein
Czasopismo naukowe

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