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Wyszukujesz frazę ""Amaryllidaceae Alkaloids"" wg kryterium: Temat


Tytuł:
Interplay between Amaryllidaceae alkaloids, the bacteriome and phytopathogens in Lycoris radiata.
Autorzy:
Zhou J; Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, 210014, Nanjing, China.
Stringlis IA; Plant-Microbe Interactions, Department of Biology, Science4Life, Utrecht University, P.O. Box 800.56, 3508 TB, Utrecht, the Netherlands.; Laboratory of Plant Pathology, Agricultural University of Athens, 75 Iera Odos St., 11855, Athens, Greece.
Wen J; Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, 210014, Nanjing, China.
Liu Y; Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, 210014, Nanjing, China.
Xu S; Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, 210014, Nanjing, China.; Jiangsu Key Laboratory for the Research and Utilization of Plant Resources, 210014, Nanjing, China.
Wang R; Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, 210014, Nanjing, China.; Jiangsu Key Laboratory for the Research and Utilization of Plant Resources, 210014, Nanjing, China.
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Źródło:
The New phytologist [New Phytol] 2024 Mar; Vol. 241 (5), pp. 2258-2274. Date of Electronic Publication: 2023 Dec 17.
Typ publikacji:
Journal Article
MeSH Terms:
Amaryllidaceae Alkaloids*/pharmacology
Amaryllidaceae Alkaloids*/chemistry
Amaryllidaceae Alkaloids*/metabolism
Lycoris*/chemistry
Lycoris*/metabolism
Alkaloids*/metabolism
Plant Extracts/chemistry
Czasopismo naukowe
Tytuł:
Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme.
Autorzy:
d'Oelsnitz S; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA. .; Synthetic Biology HIVE, Department of Systems Biology, Harvard Medical School, Boston, MA, 02115, USA. .
Diaz DJ; Department of Chemistry, University of Texas at Austin, Austin, TX, 78712, USA.; Institute for Foundations of Machine Learning, University of Texas at Austin, Austin, TX, 78712, USA.
Kim W; McKetta Department of Chemical Engineering, University of Texas at Austin, Austin, TX, 78712, USA.
Acosta DJ; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA.
Dangerfield TL; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA.
Schechter MW; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA.
Minus MB; Department of Chemistry, Prairie View A&M University, 100 University Dr, Prairie View, TX, 77446, USA.
Howard JR; Department of Chemistry, University of Texas at Austin, Austin, TX, 78712, USA.
Do H; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA.
Loy JM; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA.
Alper HS; McKetta Department of Chemical Engineering, University of Texas at Austin, Austin, TX, 78712, USA.
Zhang YJ; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA.
Ellington AD; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA.
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Źródło:
Nature communications [Nat Commun] 2024 Mar 07; Vol. 15 (1), pp. 2084. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article
MeSH Terms:
Amaryllidaceae*/metabolism
Alkaloids*/chemistry
Amaryllidaceae Alkaloids*/chemistry
Amaryllidaceae Alkaloids*/metabolism
Narcissus*/chemistry
Narcissus*/genetics
Narcissus*/metabolism
Methyltransferases/metabolism ; Plants/metabolism ; Hydrolases/metabolism
Czasopismo naukowe
Tytuł:
Molecular mechanism of lycorine in the treatment of glioblastoma based on network pharmacology and molecular docking.
Autorzy:
Su J; Department of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning, China.
Huo M; Department of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning, China.
Xu F; Department of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning, China.
Ding L; Department of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning, China. .
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Źródło:
Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2024 Mar; Vol. 397 (3), pp. 1551-1559. Date of Electronic Publication: 2023 Sep 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glioblastoma*/drug therapy
Amaryllidaceae Alkaloids*/pharmacology
Amaryllidaceae Alkaloids*/therapeutic use
Phenanthridines*
Humans ; Molecular Docking Simulation ; Network Pharmacology
Czasopismo naukowe
Tytuł:
Amaryllidaceae alkaloids from the bulbs of Crinum latifolium L. and their cholinesterase inhibitory activities.
Autorzy:
Chaichompoo W; Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand; Center of Excellence in Natural Products for Aging and Chronic Diseases, Chulalongkorn University, Bangkok 10330, Thailand.
Rojsitthisak P; Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand; Center of Excellence in Natural Products for Aging and Chronic Diseases, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: .
Pabuprapap W; Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand.
Siriwattanasathien Y; Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand.
Yotmanee P; Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand.
Suksamrarn A; Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand.
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Źródło:
Phytochemistry [Phytochemistry] 2024 Jan; Vol. 217, pp. 113929. Date of Electronic Publication: 2023 Nov 19.
Typ publikacji:
Journal Article
MeSH Terms:
Amaryllidaceae Alkaloids*/pharmacology
Amaryllidaceae Alkaloids*/chemistry
Crinum*/chemistry
Alkaloids*/pharmacology
Alkaloids*/chemistry
Butyrylcholinesterase ; Acetylcholinesterase ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/chemistry ; Plant Extracts/pharmacology ; Plant Extracts/chemistry
Czasopismo naukowe
Tytuł:
Preparation and Evaluation of Folate Modified PEG-PLLA Nanoparticles Loaded with Lycorine for Glioma Treatment.
Autorzy:
Ding J; Department of Physiology, School of Basic Medical Sciences, Hubei University of Science and Technology, Xianning 437100, China.
Su J; Department of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning 437100, China.
Luo B; Department of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning 437100, China.
Ding L; Department of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning 437100, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 29; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
Nanoparticles*/chemistry
Glioma*
Phenanthridines*
Amaryllidaceae Alkaloids*
Humans ; Folic Acid/chemistry ; Reactive Oxygen Species ; Spectroscopy, Fourier Transform Infrared ; Polyethylene Glycols/chemistry ; Drug Carriers/chemistry ; Particle Size ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Bruceine D and Narclasine inhibit the proliferation of breast cancer cells and the prediction of potential drug targets.
Autorzy:
Chen X; School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
Li H; School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
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Źródło:
PloS one [PLoS One] 2024 Jan 12; Vol. 19 (1), pp. e0297203. Date of Electronic Publication: 2024 Jan 12 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Phenanthridines*
Quassins*
Amaryllidaceae Alkaloids*
Humans ; Female ; Cytochrome P-450 CYP3A ; Cell Proliferation ; Protein Serine-Threonine Kinases
Czasopismo naukowe
Tytuł:
Lycorine and homolycorine derivatives for chemo-sensitizing resistant human ovarian adenocarcinoma cells.
Autorzy:
Sancha SAR; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal.
Dobiasová S; Department of Biochemistry and Microbiology, University of Chemistry and Technology Prague, Technická 5, CZ 166 28 Prague, Czech Republic.
Nejedlý T; Department of Biochemistry and Microbiology, University of Chemistry and Technology Prague, Technická 5, CZ 166 28 Prague, Czech Republic.
Strnad O; Department of Biochemistry and Microbiology, University of Chemistry and Technology Prague, Technická 5, CZ 166 28 Prague, Czech Republic.
Viktorová J; Department of Biochemistry and Microbiology, University of Chemistry and Technology Prague, Technická 5, CZ 166 28 Prague, Czech Republic.
Ferreira MU; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Apr; Vol. 126, pp. 155460. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
Amaryllidaceae Alkaloids*/pharmacology
Antineoplastic Agents*/pharmacology
Alkaloids*/pharmacology
Adenocarcinoma*
Phenanthridines*
Humans ; Drug Resistance, Neoplasm ; Doxorubicin/pharmacology ; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; ATP Binding Cassette Transporter, Subfamily B/metabolism ; Carbamates/pharmacology ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Auxin and light-mediated regulation of growth, morphogenesis, and alkaloid biosynthesis in Crinum x powellii 'Album' callus.
Autorzy:
Koirala M; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.
Cristine Goncalves Dos Santos K; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.
Gélinas SE; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.
Ricard S; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.
Karimzadegan V; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.
Lamichhane B; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.
Sameera Liyanage N; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.
Merindol N; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.
Desgagné-Penix I; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada; Plant Biology Research Group, Trois-Rivières, Québec, Canada. Electronic address: .
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Źródło:
Phytochemistry [Phytochemistry] 2023 Dec; Vol. 216, pp. 113883. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
Crinum*/metabolism
Amaryllidaceae Alkaloids*/pharmacology
Alkaloids*/metabolism
Indoleacetic Acids ; Plant Extracts ; Morphogenesis
Czasopismo naukowe
Tytuł:
Antiproliferative activity and apoptosis-inducing mechanism of Amaryllidaceae alkaloid montanine on A549 and MOLT-4 human cancer cells.
Autorzy:
Koutova D; Department of Medical Biochemistry, Faculty of Medicine in Hradec Kralove, Charles University, Simkova 870, Hradec Kralove 500 03, Czech Republic.
Maafi N; ADINACO Research Group, Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, Hradec Kralove 500 05, Czech Republic.
Muthna D; Department of Medical Biochemistry, Faculty of Medicine in Hradec Kralove, Charles University, Simkova 870, Hradec Kralove 500 03, Czech Republic.
Kralovec K; Department of Biological and Biochemical Sciences, Faculty of Chemical Technology, University of Pardubice, Studentska 573, Pardubice 532 10, Czech Republic.
Kroustkova J; ADINACO Research Group, Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, Hradec Kralove 500 05, Czech Republic.
Pidany F; ADINACO Research Group, Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, Hradec Kralove 500 05, Czech Republic.
Timbilla AA; Department of Medical Biochemistry, Faculty of Medicine in Hradec Kralove, Charles University, Simkova 870, Hradec Kralove 500 03, Czech Republic.
Cermakova E; Department of Medical Biophysics, Faculty of Medicine in Hradec Kralove, Charles University, Simkova 870, Hradec Kralove 500 03, Czech Republic.
Cahlikova L; ADINACO Research Group, Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, Hradec Kralove 500 05, Czech Republic.
Rezacova M; Department of Medical Biochemistry, Faculty of Medicine in Hradec Kralove, Charles University, Simkova 870, Hradec Kralove 500 03, Czech Republic.
Havelek R; Department of Medical Biochemistry, Faculty of Medicine in Hradec Kralove, Charles University, Simkova 870, Hradec Kralove 500 03, Czech Republic. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Oct; Vol. 166, pp. 115295. Date of Electronic Publication: 2023 Aug 16.
Typ publikacji:
Journal Article
MeSH Terms:
Cytostatic Agents*
Amaryllidaceae Alkaloids*/pharmacology
Antineoplastic Agents*/pharmacology
Alkaloids*
Amaryllidaceae*
Lung Neoplasms*
Humans ; Isoquinolines/pharmacology ; Apoptosis
Czasopismo naukowe
Tytuł:
Chemical and Biological Aspects of Different Species of the Genus Clinanthus Herb. (Amaryllidaceae) from South America.
Autorzy:
Rodríguez-Escobar ML; Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain.
Tallini LR; Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain.; Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre 90610-000, RS, Brazil.
Lisa-Molina J; Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain.
Berkov S; Department of Plant and Fungal Diversity, Institute of Biodiversity and Ecosystem Research at the Bulgarian Academy of Sciences, 23 Acad. G. Bonchev Str., 1113 Sofia, Bulgaria.
Viladomat F; Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain.
Meerow A; School of Life Sciences, Arizona State University, Tempe, AZ 85282, USA.
Bastida J; Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain.
Torras-Claveria L; Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jul 14; Vol. 28 (14). Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Journal Article
MeSH Terms:
Amaryllidaceae Alkaloids*/pharmacology
Amaryllidaceae*/chemistry
Alkaloids*/chemistry
Butyrylcholinesterase/chemistry ; Cholinesterase Inhibitors/chemistry ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; South America
Czasopismo naukowe
Tytuł:
Anti-SARS-CoV-2 Activity and Cytotoxicity of Amaryllidaceae Alkaloids from Hymenocallis littoralis .
Autorzy:
Le NT; Natural Products and Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.
De Jonghe S; Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.
Erven K; Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.
Vermeyen T; Department of Chemistry, University of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, Belgium.; Ghent Quantum Chemistry Group, Department of Chemistry, Ghent University, Krijgslaan 281, B-9000 Ghent, Belgium.
Baldé AM; Department of Pharmacy, University Gamal Abdel Nasser of Conakry, Conakry 00224, Guinea.
Herrebout WA; Department of Chemistry, University of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, Belgium.
Neyts J; Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.
Pannecouque C; Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.
Pieters L; Natural Products and Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.
Tuenter E; Natural Products and Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Apr 04; Vol. 28 (7). Date of Electronic Publication: 2023 Apr 04.
Typ publikacji:
Journal Article
MeSH Terms:
Amaryllidaceae Alkaloids*/pharmacology
Amaryllidaceae Alkaloids*/chemistry
COVID-19*
Amaryllidaceae*/chemistry
Liliaceae*
Czasopismo naukowe
Tytuł:
Highly selective butyrylcholinesterase inhibitors related to Amaryllidaceae alkaloids - Design, synthesis, and biological evaluation.
Autorzy:
Pidany F; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05, Hradec Kralove, Czech Republic.
Kroustkova J; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05, Hradec Kralove, Czech Republic.
Al Mamun A; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05, Hradec Kralove, Czech Republic.
Suchankova D; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05, Hradec Kralove, Czech Republic.
Brazzolotto X; Institut de Recherche Biomédicale des Armées, Département de Toxicologie et Risques Chimiques, 1 Place Général Valérie André, 91220, Brétigny-sur-Orge, France.
Nachon F; Institut de Recherche Biomédicale des Armées, Département de Toxicologie et Risques Chimiques, 1 Place Général Valérie André, 91220, Brétigny-sur-Orge, France.
Chantegreil F; Institut de Recherche Biomédicale des Armées, Département de Toxicologie et Risques Chimiques, 1 Place Général Valérie André, 91220, Brétigny-sur-Orge, France.
Dolezal R; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.
Pulkrabkova L; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic.
Muckova L; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic.
Hrabinova M; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic.
Finger V; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic; Department of Bioorganic and Organic Chemistry, Faculty of Pharmacy Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05, Hradec Kralove, Czech Republic.
Kufa M; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic; Department of Bioorganic and Organic Chemistry, Faculty of Pharmacy Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05, Hradec Kralove, Czech Republic.
Soukup O; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic.
Jun D; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic.
Jenco J; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05, Hradec Kralove, Czech Republic.
Kunes J; Department of Bioorganic and Organic Chemistry, Faculty of Pharmacy Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05, Hradec Kralove, Czech Republic.
Novakova L; Department of Analytical Chemistry, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05, Hradec Kralove, Czech Republic.
Korabecny J; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic. Electronic address: .
Cahlikova L; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 500 05, Hradec Kralove, Czech Republic. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2023 Apr 05; Vol. 252, pp. 115301. Date of Electronic Publication: 2023 Mar 22.
Typ publikacji:
Journal Article
MeSH Terms:
Amaryllidaceae Alkaloids*/pharmacology
Neuroblastoma*/drug therapy
Alzheimer Disease*/drug therapy
Humans ; Butyrylcholinesterase/metabolism ; Cholinesterase Inhibitors/chemistry ; Acetylcholinesterase/metabolism ; Molecular Docking Simulation ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Amaryllidaceae alkaloids in skin cancer management: Photoprotective effect on human keratinocytes and anti-proliferative activity in melanoma cells.
Autorzy:
Castaneda C; Universidad de Antioquia, Facultad de Ciencias Farmaceuticas y Alimentarias, Grupo de Investigacion en Sustancias Bioactivas, Medellin, Colombia.
Bravo K; Universidad de Antioquia, Facultad de Ciencias Farmaceuticas y Alimentarias, Grupo de Investigacion en Sustancias Bioactivas, Medellin, Colombia.
Cortes N; Universidad de Antioquia, Facultad de Ciencias Farmaceuticas y Alimentarias, Grupo de Investigacion en Sustancias Bioactivas, Medellin, Colombia.; Universidad de Ibague, Facultad de Ciencias Naturales y Matematicas, Ibague, Colombia.
Bedoya J; Universidad de Antioquia, Facultad de Medicina, Grupo Medicina Molecular y de Translacion, Medellin, Colombia.
de Borges WS; Universidade Federal do Espirito Santo, Departamento de Quimica, Vitoria, Espirito Santo, Brazil.
Bastida J; Universitat de Barcelona, Facultat de Farmacia i Ciencies de l'Alimentacio, Departament de Biologia, Sanitat i Medi Ambient, Barcelona, Spain.
Osorio E; Universidad de Antioquia, Facultad de Ciencias Farmaceuticas y Alimentarias, Grupo de Investigacion en Sustancias Bioactivas, Medellin, Colombia.
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Źródło:
Journal of applied biomedicine [J Appl Biomed] 2023 Apr; Vol. 21 (1), pp. 36-47. Date of Electronic Publication: 2023 Mar 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amaryllidaceae Alkaloids*/pharmacology
Alkaloids*/pharmacology
Skin Neoplasms*/drug therapy
Melanoma*/drug therapy
Humans ; Reactive Oxygen Species/pharmacology ; Interleukin-6 ; Keratinocytes
Czasopismo naukowe
Tytuł:
Gas chromatography-mass spectrometry of some homolycorine-type Amaryllidaceae alkaloids.
Autorzy:
Berkov S; Institute of Biodiversity and Ecosystem Research at the Bulgarian Academy of Sciences, Sofia, Bulgaria.
Denev R; Institute of Biodiversity and Ecosystem Research at the Bulgarian Academy of Sciences, Sofia, Bulgaria.
Sidjimova B; Institute of Biodiversity and Ecosystem Research at the Bulgarian Academy of Sciences, Sofia, Bulgaria.
Zarev Y; Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
Shkondrov A; Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
Torras-Claveria L; Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de la Salut, Grup de Productes Naturals, Barcelona, Catalonia, Spain.
Viladomat F; Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de la Salut, Grup de Productes Naturals, Barcelona, Catalonia, Spain.
Bastida J; Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de la Salut, Grup de Productes Naturals, Barcelona, Catalonia, Spain.
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Źródło:
Rapid communications in mass spectrometry : RCM [Rapid Commun Mass Spectrom] 2023 Jun 30; Vol. 37 (12), pp. e9506.
Typ publikacji:
Journal Article
MeSH Terms:
Amaryllidaceae Alkaloids*/chemistry
Alkaloids*/chemistry
Amaryllidaceae*
Gas Chromatography-Mass Spectrometry ; Plant Extracts/chemistry
Czasopismo naukowe
Tytuł:
ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T-Cell Metabolism.
Autorzy:
Tan X; Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Ministry of Education, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; NHC Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.
Qi C; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430030, P. R. China.
Zhao X; Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Ministry of Education, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; NHC Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.
Sun L; Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Ministry of Education, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; NHC Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.
Wu M; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430030, P. R. China.
Sun W; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430030, P. R. China.
Gu L; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430030, P. R. China.
Wang F; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430030, P. R. China.
Feng H; Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Ministry of Education, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; NHC Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.
Huang X; Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Ministry of Education, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; NHC Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.
Xie B; Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Ministry of Education, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; NHC Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.
Shi Z; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430030, P. R. China.
Xie P; Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Ministry of Education, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; NHC Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.
Wu M; Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Ministry of Education, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; NHC Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.
Zhang Y; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430030, P. R. China.
Chen G; Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Ministry of Education, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; NHC Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, Hubei Province, 430030, P. R. China.
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Źródło:
Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2023 Jun; Vol. 10 (16), pp. e2206768. Date of Electronic Publication: 2023 Apr 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
T-Lymphocytes*
Amaryllidaceae Alkaloids*/metabolism
Mice ; Humans ; Animals ; Protein Kinases/metabolism ; Proteins/metabolism ; Allografts
Czasopismo naukowe
Tytuł:
Advances on the Amaryllidacea Alkaloids Collected in South Africa, Andean South America and the Mediterranean Basin.
Autorzy:
Evidente A; Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy.; Institute of Sciences of Food Production, National Research Council, Via Amendola 122/O, 70185 Bari, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 12; Vol. 28 (10). Date of Electronic Publication: 2023 May 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Alkaloids*
Narcissus*/chemistry
Amaryllidaceae*
Amaryllidaceae Alkaloids*/chemistry
Plant Extracts/chemistry ; South Africa
Czasopismo naukowe
Tytuł:
Lycorine induces apoptosis of acute myeloid leukemia cells and inhibits triglyceride production via binding and targeting FABP5.
Autorzy:
Liang X; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, School of Basic Medical Science, Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Fu W; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, School of Basic Medical Science, Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Peng Y; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, School of Basic Medical Science, Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Duan J; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, School of Basic Medical Science, Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Zhang T; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, School of Basic Medical Science, Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Fan D; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, School of Basic Medical Science, Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Hong W; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, School of Basic Medical Science, Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Qi X; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, School of Basic Medical Science, Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Wu C; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, School of Basic Medical Science, Guizhou Medical University, Guiyang, 550004, Guizhou, China.
He Y; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, School of Basic Medical Science, Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Yu W; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, School of Basic Medical Science, Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Zhou J; School of Biology and Engineering, Guizhou Medical University, Guiyang, China.
Guo P; Department of Hematology, Guizhou Provincial People's Hospital, Guizhou University, Guiyang, 550002, Guizhou, China. .
Bai H; Medical Laboratory Center, the Third Affiliated Hospital of Guizhou Medical University, Duyun, 558000, Guizhou, China. .
Zhang Q; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, School of Basic Medical Science, Guizhou Medical University, Guiyang, 550004, Guizhou, China. .; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research On Common Chronic Diseases, Guiyang, 550004, Guizhou, China. .
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Źródło:
Annals of hematology [Ann Hematol] 2023 May; Vol. 102 (5), pp. 1073-1086. Date of Electronic Publication: 2023 Mar 21.
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/metabolism
Amaryllidaceae Alkaloids*
Humans ; Cell Line, Tumor ; Apoptosis ; Cell Proliferation ; Fatty Acid-Binding Proteins/genetics
Czasopismo naukowe
Tytuł:
Cytotoxic Activity of Amaryllidaceae Plants against Cancer Cells: Biotechnological, In Vitro, and In Silico Approaches.
Autorzy:
Trujillo L; Grupo de Investigación en Sustancias Bioactivas GISB, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, Calle 70 No. 52-21, Medellín 050010, Colombia.
Bedoya J; Grupo Medicina Molecular y de Translación, Facultad de Medicina, Universidad de Antioquia, Carrera 51 D No. 62-29, Medellín 050010, Colombia.
Cortés N; Facultad de Ciencias Naturales y Matemáticas, Universidad de Ibagué, Carrera 22 Calle 67, Ibagué 730002, Colombia.
Osorio EH; Facultad de Ciencias Naturales y Matemáticas, Universidad de Ibagué, Carrera 22 Calle 67, Ibagué 730002, Colombia.
Gallego JC; Grupo Medicina Molecular y de Translación, Facultad de Medicina, Universidad de Antioquia, Carrera 51 D No. 62-29, Medellín 050010, Colombia.
Leiva H; Unidad de Biotecnología Vegetal, Facultad de Ingeniería, Universidad Católica de Oriente, Rionegro 054040, Colombia.
Castro D; Unidad de Biotecnología Vegetal, Facultad de Ingeniería, Universidad Católica de Oriente, Rionegro 054040, Colombia.
Osorio E; Grupo de Investigación en Sustancias Bioactivas GISB, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, Calle 70 No. 52-21, Medellín 050010, Colombia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Mar 13; Vol. 28 (6). Date of Electronic Publication: 2023 Mar 13.
Typ publikacji:
Journal Article
MeSH Terms:
Amaryllidaceae*/chemistry
Alkaloids*/chemistry
Amaryllidaceae Alkaloids*/pharmacology
Antineoplastic Agents*
Neoplasms*
Plant Extracts/pharmacology ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł:
Lycorine protects against septic myocardial injury by activating AMPK-related pathways.
Autorzy:
Zhao H; Department of General Surgery, Tangdu Hospital, The Airforce Military Medical University, 1 Xinsi Road, Xi'an, China.
Chen Y; Department of Hematology, The First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, China.
Qian L; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. School of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China; Department of Neurology, Xi'an No.3 Hospital, The Affiliated Hospital of Northwest University. Faculty of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Du L; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. School of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China; Department of Neurology, Xi'an No.3 Hospital, The Affiliated Hospital of Northwest University. Faculty of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Wu X; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. School of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China; Department of Neurology, Xi'an No.3 Hospital, The Affiliated Hospital of Northwest University. Faculty of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Tian Y; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. School of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China; Department of Neurology, Xi'an No.3 Hospital, The Affiliated Hospital of Northwest University. Faculty of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Deng C; Department of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, China.
Liu S; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. School of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China; Department of Neurology, Xi'an No.3 Hospital, The Affiliated Hospital of Northwest University. Faculty of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Yang W; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. School of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China; Department of Neurology, Xi'an No.3 Hospital, The Affiliated Hospital of Northwest University. Faculty of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Lu C; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. School of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China; Department of Neurology, Xi'an No.3 Hospital, The Affiliated Hospital of Northwest University. Faculty of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Zhang Y; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. School of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China; Department of Neurology, Xi'an No.3 Hospital, The Affiliated Hospital of Northwest University. Faculty of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China.
Ren J; Department of Cardiology, Zhongshan Hospital, Fudan University; Shanghai Institute of Cardiovascular Diseases, Shanghai, China. Electronic address: jren_.
Yang Y; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education. School of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, China; Department of Neurology, Xi'an No.3 Hospital, The Affiliated Hospital of Northwest University. Faculty of Life Sciences and Medicine, Northwest University, 10 Fengcheng Three Road, Xi'an, China. Electronic address: .
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Źródło:
Free radical biology & medicine [Free Radic Biol Med] 2023 Mar; Vol. 197, pp. 1-14. Date of Electronic Publication: 2023 Jan 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amaryllidaceae Alkaloids*/pharmacology
Amaryllidaceae Alkaloids*/therapeutic use
Amaryllidaceae Alkaloids*/metabolism
Heart Injuries*
Sepsis*/drug therapy
Sepsis*/complications
Animals ; Mice ; AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/metabolism ; Myocardium/metabolism
Czasopismo naukowe
Tytuł:
Structurally diverse alkaloids with nine frameworks from Zephyranthes candida and their acetylcholinesterase inhibitory and anti-inflammatory activities.
Autorzy:
Zhan G; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Gao B; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Zhou J; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Liu T; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Zheng G; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Jin Z; State Key Laboratory of Elementoorganic Chemistry, College of Chemistry, Nankai University, Tianjin, 300071, China; Laboratory of Xinjiang Native Medicinal and Edible Plant Resource Chemistry, College of Chemistry and Environmental Science, Kashi University, Kashgar, 844007, China. Electronic address: .
Yao G; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China; Laboratory of Xinjiang Native Medicinal and Edible Plant Resource Chemistry, College of Chemistry and Environmental Science, Kashi University, Kashgar, 844007, China. Electronic address: .
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Źródło:
Phytochemistry [Phytochemistry] 2023 Mar; Vol. 207, pp. 113564. Date of Electronic Publication: 2022 Dec 16.
Typ publikacji:
Journal Article
MeSH Terms:
Amaryllidaceae Alkaloids*/pharmacology
Amaryllidaceae Alkaloids*/chemistry
Alkaloids*/pharmacology
Alkaloids*/chemistry
Amaryllidaceae*/chemistry
Mice ; Animals ; Acetylcholinesterase ; Anti-Inflammatory Agents/pharmacology ; Candida ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/chemistry
Czasopismo naukowe

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