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Wyszukujesz frazę ""Amiloride"" wg kryterium: Temat


Tytuł :
An Inhibitor of the Sodium-Hydrogen Exchanger-1 (NHE-1), Amiloride, Reduced Zinc Accumulation and Hippocampal Neuronal Death after Ischemia.
Autorzy :
Kang BS; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Choi BY; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Kho AR; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Lee SH; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Hong DK; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Jeong JH; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Kang DH; Department of Medical Science, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Park MK; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Suh SW; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jun 14; Vol. 21 (12). Date of Electronic Publication: 2020 Jun 14.
Typ publikacji :
Journal Article
MeSH Terms :
Acidosis/*prevention & control
Amiloride/*administration & dosage
Brain Ischemia/*drug therapy
Epithelial Sodium Channel Blockers/*administration & dosage
Hippocampus/*metabolism
Zinc/*metabolism
Acidosis/etiology ; Acidosis/metabolism ; Amiloride/pharmacology ; Animals ; Brain Ischemia/complications ; Brain Ischemia/metabolism ; Cell Death/drug effects ; Disease Models, Animal ; Epithelial Sodium Channel Blockers/pharmacology ; Hippocampus/drug effects ; Injections, Intraperitoneal ; Male ; Mice ; Neurons/drug effects ; Neurons/metabolism ; Oxidative Stress/drug effects
Czasopismo naukowe
Tytuł :
Urokinase-type Plasminogen Activator Is a Therapeutic Target for Overcoming Sorafenib Resistance in Hepatoma Cells.
Autorzy :
Osawa M; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Matsuda Y; Department of Medical Technology, Niigata University Graduate School of Health Sciences, Niigata, Japan; .
Kinoshita Y; Department of Pediatric Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Wakai T; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
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Źródło :
Anticancer research [Anticancer Res] 2021 Feb; Vol. 41 (2), pp. 645-660.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Neoplasm*/drug effects
Antineoplastic Agents/*pharmacology
Carcinoma, Hepatocellular/*drug therapy
Liver Neoplasms/*drug therapy
Membrane Proteins/*metabolism
Protein Kinase Inhibitors/*pharmacology
Sorafenib/*pharmacology
Amiloride/pharmacology ; Animals ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Apoptosis/drug effects ; Carcinoma, Hepatocellular/enzymology ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Cell Proliferation/drug effects ; Hep G2 Cells ; Humans ; Liver Neoplasms/enzymology ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Male ; Membrane Proteins/antagonists & inhibitors ; Membrane Proteins/genetics ; Mice, Inbred BALB C ; Mice, Nude ; Proto-Oncogene Proteins c-akt/metabolism ; RNA Interference ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Greater natriuretic response to ENaC inhibition in male versus female Sprague-Dawley rats.
Autorzy :
Soliman RH; Section of Cardio-renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Johnston JG; Section of Cardio-renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Gohar EY; Section of Cardio-renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Taylor CM; Section of Cardio-renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Pollock DM; Section of Cardio-renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
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Źródło :
American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2020 Feb 01; Vol. 318 (2), pp. R418-R427. Date of Electronic Publication: 2020 Jan 08.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Amiloride/*analogs & derivatives
Epithelial Sodium Channel Blockers/*pharmacology
Epithelial Sodium Channels/*drug effects
Kidney/*drug effects
Natriuresis/*drug effects
Activity Cycles ; Amiloride/pharmacology ; Animals ; Endothelin-1/urine ; Epithelial Sodium Channels/metabolism ; Female ; Kidney/metabolism ; Male ; Ovariectomy ; Rats, Sprague-Dawley ; Renal Elimination/drug effects ; Sex Factors ; Time Factors ; Urodynamics/drug effects
Czasopismo naukowe
Tytuł :
6-Substituted amiloride derivatives as inhibitors of the urokinase-type plasminogen activator for use in metastatic disease.
Autorzy :
Buckley BJ; School of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia; Illawarra Health and Medical Research Institute, NSW 2522, Australia; Molecular Horizons, University of Wollongong, NSW 2522, Australia.
Majed H; School of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia; Illawarra Health and Medical Research Institute, NSW 2522, Australia; Molecular Horizons, University of Wollongong, NSW 2522, Australia.
Aboelela A; School of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia; Illawarra Health and Medical Research Institute, NSW 2522, Australia; Molecular Horizons, University of Wollongong, NSW 2522, Australia.
Minaei E; Illawarra Health and Medical Research Institute, NSW 2522, Australia; Molecular Horizons, University of Wollongong, NSW 2522, Australia.
Jiang L; National Joint Biomdical Engineering Research Centre on Photodynamic Technologies, Fuzhou University, Fuzhou 350116, China.
Fildes K; Illawarra Health and Medical Research Institute, NSW 2522, Australia; Graduate School of Medicine, University of Wollongong, NSW 2522, Australia.
Cheung CY; Department of Microbiology and Immunology, University of Otago, Otago 9016, New Zealand.
Johnson D; Tri-institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, NY 10065, USA.
Bachovchin D; Tri-institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, NY 10065, USA; Chemical Biology Program, Memorial Sloan Kettering Cancer Centre, NY 10065, USA.
Cook GM; Department of Microbiology and Immunology, University of Otago, Otago 9016, New Zealand.
Huang M; National Joint Biomdical Engineering Research Centre on Photodynamic Technologies, Fuzhou University, Fuzhou 350116, China.
Ranson M; School of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia; Illawarra Health and Medical Research Institute, NSW 2522, Australia; Molecular Horizons, University of Wollongong, NSW 2522, Australia. Electronic address: .
Kelso MJ; School of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia; Illawarra Health and Medical Research Institute, NSW 2522, Australia; Molecular Horizons, University of Wollongong, NSW 2522, Australia. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Dec 15; Vol. 29 (24), pp. 126753. Date of Electronic Publication: 2019 Oct 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Amiloride/*analogs & derivatives
Amiloride/*therapeutic use
Diuretics/*therapeutic use
Neoplasm Metastasis/*drug therapy
Urokinase-Type Plasminogen Activator/*antagonists & inhibitors
Amiloride/pharmacology ; Diuretics/pharmacology ; Humans ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Efficacy of chlorthalidone and hydrochlorothiazide in combination with amiloride in multiple doses on blood pressure in patients with primary hypertension: a protocol for a factorial randomized controlled trial.
Autorzy :
Martins VM; Graduate Program in Cardiology and Cardiovascular Sciences, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. .
Helal L; Graduate Program in Cardiology and Cardiovascular Sciences, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Ferrari F; Graduate Program in Cardiology and Cardiovascular Sciences, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Bottino LG; Graduate Program in Cardiology and Cardiovascular Sciences, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Fuchs SC; Graduate Program in Cardiology and Cardiovascular Sciences, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Fuchs FD; Graduate Program in Cardiology and Cardiovascular Sciences, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.; Division of Cardiology, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
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Źródło :
Trials [Trials] 2019 Dec 16; Vol. 20 (1), pp. 736. Date of Electronic Publication: 2019 Dec 16.
Typ publikacji :
Clinical Trial Protocol; Journal Article
MeSH Terms :
Amiloride/*administration & dosage
Antihypertensive Agents/*administration & dosage
Blood Pressure/*drug effects
Chlorthalidone/*administration & dosage
Hydrochlorothiazide/*administration & dosage
Hypertension/*drug therapy
Sodium Chloride Symporter Inhibitors/*administration & dosage
Amiloride/adverse effects ; Antihypertensive Agents/adverse effects ; Brazil ; Chlorthalidone/adverse effects ; Double-Blind Method ; Drug Combinations ; Humans ; Hydrochlorothiazide/adverse effects ; Hypertension/diagnosis ; Hypertension/physiopathology ; Randomized Controlled Trials as Topic ; Sodium Chloride Symporter Inhibitors/adverse effects ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers.
Autorzy :
Mandala VS; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.
McKay MJ; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.
Shcherbakov AA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.
Dregni AJ; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.
Kolocouris A; Department of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimioupolis Zografou, Athens, Greece.
Hong M; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA. .
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Źródło :
Nature structural & molecular biology [Nat Struct Mol Biol] 2020 Dec; Vol. 27 (12), pp. 1202-1208. Date of Electronic Publication: 2020 Nov 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus Envelope Proteins/*chemistry
Lipid Bilayers/*chemistry
SARS-CoV-2/*chemistry
Amantadine/chemistry ; Amiloride/analogs & derivatives ; Amiloride/chemistry ; Antiviral Agents/chemistry ; Coronavirus Envelope Proteins/genetics ; Dimyristoylphosphatidylcholine/chemistry ; Hydrogen-Ion Concentration ; Magnetic Resonance Spectroscopy ; Models, Molecular ; Phenylalanine/chemistry ; Phospholipids/chemistry ; Protein Conformation ; Protein Domains ; SARS-CoV-2/genetics
Czasopismo naukowe
Tytuł :
Is amiloride a promising cardiovascular medication to persist in the COVID-19 crisis?
Autorzy :
Adil MS; Clinical and Experimental Therapeutics, University of Georgia and Charlie Norwood VA Medical Center, Augusta, GA, USA.
Narayanan SP; Clinical and Experimental Therapeutics, University of Georgia and Charlie Norwood VA Medical Center, Augusta, GA, USA.
Somanath PR; Clinical and Experimental Therapeutics, University of Georgia and Charlie Norwood VA Medical Center, Augusta, GA, USA.
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Źródło :
Drug discoveries & therapeutics [Drug Discov Ther] 2020 Nov 04; Vol. 14 (5), pp. 256-258. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article
MeSH Terms :
Amiloride/*pharmacology
Antiviral Agents/*pharmacology
Betacoronavirus/*drug effects
Coronavirus Infections/*drug therapy
Epithelial Sodium Channel Blockers/*pharmacology
Pneumonia, Viral/*drug therapy
Respiratory Mucosa/*drug effects
Virus Internalization/*drug effects
A549 Cells ; Angiotensin-Converting Enzyme 2 ; Betacoronavirus/pathogenicity ; COVID-19 ; Cardiovascular Diseases/drug therapy ; Cardiovascular Diseases/enzymology ; Coronavirus Infections/enzymology ; Coronavirus Infections/virology ; Down-Regulation ; Host-Pathogen Interactions ; Humans ; Pandemics ; Peptidyl-Dipeptidase A/metabolism ; Pneumonia, Viral/enzymology ; Pneumonia, Viral/virology ; Receptors, Virus/metabolism ; Respiratory Mucosa/enzymology ; Respiratory Mucosa/virology ; SARS-CoV-2
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Induction of apoptosis and differentiation by Na/H exchanger 1 modulation in acute myeloid leukemia cells.
Autorzy :
Hyun SY; Department of Internal Medicine, Yonsei University Wonju College of Medicine, 20 Ilsanro-ro, Wonju-si, Kangwon-do, South Korea.
Na EJ; Department of Internal Medicine, Yonsei University Wonju College of Medicine, 20 Ilsanro-ro, Wonju-si, Kangwon-do, South Korea.
Jang JE; Avison Biomedical Research Center, Yonsei University College of Medicine, Seoul, South Korea; Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
Chung H; Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
Kim SJ; Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
Kim JS; Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
Kong JH; Department of Internal Medicine, Yonsei University Wonju College of Medicine, 20 Ilsanro-ro, Wonju-si, Kangwon-do, South Korea.
Shim KY; Department of Internal Medicine, Yonsei University Wonju College of Medicine, 20 Ilsanro-ro, Wonju-si, Kangwon-do, South Korea.
Lee JI; Department of Internal Medicine, Yonsei University Wonju College of Medicine, 20 Ilsanro-ro, Wonju-si, Kangwon-do, South Korea.
Min YH; Avison Biomedical Research Center, Yonsei University College of Medicine, Seoul, South Korea; Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
Cheong JW; Avison Biomedical Research Center, Yonsei University College of Medicine, Seoul, South Korea; Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2019 Nov 19; Vol. 519 (4), pp. 887-893. Date of Electronic Publication: 2019 Sep 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amiloride/*pharmacology
Apoptosis/*drug effects
Cell Differentiation/*drug effects
Sodium-Hydrogen Exchanger 1/*antagonists & inhibitors
Tetradecanoylphorbol Acetate/*pharmacology
Acute Disease ; Amiloride/chemistry ; Antineoplastic Agents/pharmacology ; Cell Proliferation/drug effects ; G1 Phase Cell Cycle Checkpoints/drug effects ; Humans ; K562 Cells ; Leukemia, Myeloid/genetics ; Leukemia, Myeloid/metabolism ; Leukemia, Myeloid/pathology ; Sodium-Hydrogen Exchanger 1/genetics ; Sodium-Hydrogen Exchanger 1/metabolism
Czasopismo naukowe
Tytuł :
Benzamil inhibits neuronal and heterologously expressed small conductance Ca channels.
Autorzy :
Castañeda MS; Research Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK; Kinases and Brain Development Laboratory, The Francis Crick Institute, London, UK.
Tonini R; Research Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK; Neuromodulation of Cortical and Subcortical Circuits Laboratory, Fondazione Istituto Italiano di Tecnologia, Genova, Italy.
Richards CD; Research Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK.
Stocker M; Research Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK. Electronic address: .
Pedarzani P; Research Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK. Electronic address: .
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Źródło :
Neuropharmacology [Neuropharmacology] 2019 Nov 01; Vol. 158, pp. 107738. Date of Electronic Publication: 2019 Aug 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Action Potentials/*drug effects
Amiloride/*analogs & derivatives
Pyramidal Cells/*drug effects
Small-Conductance Calcium-Activated Potassium Channels/*antagonists & inhibitors
Action Potentials/physiology ; Amiloride/pharmacology ; Animals ; Calcium/metabolism ; Dendrites/drug effects ; Dendrites/metabolism ; Female ; HEK293 Cells ; Hippocampus/cytology ; Humans ; Male ; Neurons/drug effects ; Neurons/metabolism ; Optical Imaging ; Patch-Clamp Techniques ; Primary Cell Culture ; Pyramidal Cells/metabolism ; Rats
Czasopismo naukowe
Tytuł :
Driving factors in amiloride recognition of HIV RNA targets.
Autorzy :
Patwardhan NN; Department of Chemistry, Duke University, 124 Science Drive, Durham, NC 27705, USA. .
Cai Z
Umuhire Juru A
Hargrove AE
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Źródło :
Organic & biomolecular chemistry [Org Biomol Chem] 2019 Oct 30; Vol. 17 (42), pp. 9313-9320.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amiloride/*chemistry
HIV/*genetics
RNA, Viral/*chemistry
Amiloride/pharmacology ; Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Cheminformatics ; Drug Discovery ; Nucleic Acid Conformation ; RNA Splicing ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/metabolism
Czasopismo naukowe
Tytuł :
Enhanced Cellular Uptake Of Phenamil Through Inclusion Complex With Histidine Functionalized β-Cyclodextrin As Penetrative Osteoinductive Agent.
Autorzy :
Jahed V; Biomedical Engineering Division, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran, Iran.
Vasheghani-Farahani E; Biomedical Engineering Division, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran, Iran.
Bagheri F; Department of Biotechnology, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran, Iran.
Zarrabi A; Sabanci University Nanotechnology Research and Application Center (SUNUM), Tuzla 34956, Istanbul, Turkey.
Fink T; Department of Health Science and Technology, Faculty of Health, Aalborg University, Aalborg, Denmark.
Lambertsen Larsen K; Department of Chemistry and Bioscience, Faculty of Chemistry, Aalborg University, Aalborg, Denmark.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2019 Oct 11; Vol. 14, pp. 8221-8234. Date of Electronic Publication: 2019 Oct 11 (Print Publication: 2019).
Typ publikacji :
Journal Article
MeSH Terms :
Endocytosis*
Osseointegration*/drug effects
2-Hydroxypropyl-beta-cyclodextrin/*chemistry
Amiloride/*analogs & derivatives
Histidine/*chemistry
Stem Cells/*metabolism
2-Hydroxypropyl-beta-cyclodextrin/chemical synthesis ; Adipose Tissue/cytology ; Amiloride/pharmacology ; Calcification, Physiologic/drug effects ; Cell Survival/drug effects ; Humans ; Molecular Docking Simulation ; Osteogenesis/drug effects ; Particle Size ; Proton Magnetic Resonance Spectroscopy ; Solubility ; Spectroscopy, Fourier Transform Infrared ; Static Electricity
Czasopismo naukowe
Tytuł :
Optogenetic Stimulation of Type I GAD65 Cells in Taste Buds Activates Gustatory Neurons and Drives Appetitive Licking Behavior in Sodium-Depleted Mice.
Autorzy :
Baumer-Harrison C; Department of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Raymond MA; Department of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Myers TA; Department of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Sussman KM; Department of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Rynberg ST; Department of Biology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Ugartechea AP; Department of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Lauterbach D; Department of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Mast TG; Department of Biology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.; Program in Neuroscience, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
Breza JM; Department of Psychology, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197 .; Program in Neuroscience, College of Arts and Sciences, Eastern Michigan University, Ypsilanti, Michigan 48197.
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Oct 07; Vol. 40 (41), pp. 7795-7810. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Appetite/*physiology
Food Preferences/*physiology
Glutamate Decarboxylase/*physiology
Optogenetics/*methods
Sensory Receptor Cells/*physiology
Sodium/*deficiency
Taste Buds/*physiology
Amiloride/pharmacology ; Animals ; Appetite/drug effects ; Channelrhodopsins ; Cranial Nerves/physiology ; Diuretics/pharmacology ; Female ; Food Preferences/drug effects ; Glutamate Decarboxylase/drug effects ; Male ; Mice ; Sensory Receptor Cells/drug effects ; Sodium Chloride/pharmacology ; Taste Buds/drug effects
Czasopismo naukowe
Tytuł :
Registration of amiloride in South Africa: Cutting the Gordian knot.
Autorzy :
Rayner BL; Division of Nephrology, Department of Medicine, Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa. .
Spence JD
Bryer A
Mpe MT
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Źródło :
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde [S Afr Med J] 2019 Aug 28; Vol. 109 (9), pp. 632-634. Date of Electronic Publication: 2019 Aug 28.
Typ publikacji :
Journal Article
MeSH Terms :
Amiloride/*therapeutic use
Antihypertensive Agents/*therapeutic use
Drug and Narcotic Control/*legislation & jurisprudence
Hypertension/*drug therapy
African Continental Ancestry Group/statistics & numerical data ; Amiloride/pharmacology ; Antihypertensive Agents/pharmacology ; Blood Pressure/drug effects ; Diuretics/pharmacology ; Diuretics/therapeutic use ; Epithelial Sodium Channel Blockers/pharmacology ; Epithelial Sodium Channel Blockers/therapeutic use ; Health Status Disparities ; Humans ; Hypertension/physiopathology ; South Africa
Czasopismo naukowe
Tytuł :
Amiloride Relaxes Rat Corpus Cavernosum Relaxation In Vitro and Increases Intracavernous Pressure In Vivo.
Autorzy :
Campos R; Superior Institute of Biomedical Sciences, Ceará State University, Fortaleza, Ceará, Brazil; Faculty of Medical Sciences, Department of Pharmacology, University of Campinas (UNICAMP), Campinas, Brazil. Electronic address: .
Claudino MA; Faculty of Medical Sciences, Department of Pharmacology, University of Campinas (UNICAMP), Campinas, Brazil; Laboratory of Multidisciplinary Research, São Francisco University (USF), Bragança Paulista (São Paulo), Brazil.
de Oliveira MG; Faculty of Medical Sciences, Department of Pharmacology, University of Campinas (UNICAMP), Campinas, Brazil.
Franco-Penteado CF; Hematology and Hemotherapy Center, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas (São Paulo), Brazil.
Del Grossi Ferraz Carvalho F; Faculty of Medical Sciences, Department of Pharmacology, University of Campinas (UNICAMP), Campinas, Brazil.
Zaminelli T; Department of Pharmacology, University of São Paulo, São Paulo, Brazil.
Antunes E; Faculty of Medical Sciences, Department of Pharmacology, University of Campinas (UNICAMP), Campinas, Brazil.
De Nucci G; Faculty of Medical Sciences, Department of Pharmacology, University of Campinas (UNICAMP), Campinas, Brazil; Department of Pharmacology, University of São Paulo, São Paulo, Brazil.
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Źródło :
The journal of sexual medicine [J Sex Med] 2019 Apr; Vol. 16 (4), pp. 500-511. Date of Electronic Publication: 2019 Mar 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amiloride/*pharmacology
Penile Erection/*drug effects
Penis/*drug effects
Amiloride/analogs & derivatives ; Animals ; Cyclic Nucleotide Phosphodiesterases, Type 5/metabolism ; Erectile Dysfunction/drug therapy ; Male ; Muscle Contraction/drug effects ; Muscle Relaxation/drug effects ; Nitroprusside/pharmacology ; Phenylephrine/pharmacology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Simultaneous spectrofluorometric analysis of tablets containing hydrochlorothiazide combined with timolol maleate or amiloride hydrochloride.
Autorzy :
Wedian F; Department of Chemistry Faculty of Science, Yarmouk UniversityP.O. Box 560,Irbid22163,Jordan.
Lataifeh A; Department of Chemistry Faculty of Science, Tafila Technical University, Tafila66110, Jordan.
Mohammed MS; Department of Chemistry Faculty of Science, Yarmouk UniversityP.O. Box 560,Irbid22163,Jordan.
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Źródło :
Acta pharmaceutica (Zagreb, Croatia) [Acta Pharm] 2020 Sep 01; Vol. 70 (3), pp. 373-385.
Typ publikacji :
Journal Article; Validation Study
MeSH Terms :
Amiloride/*analysis
Hydrochlorothiazide/*analysis
Spectrometry, Fluorescence/*methods
Timolol/*analysis
Drug Combinations ; Limit of Detection ; Reproducibility of Results ; Tablets ; Temperature
Czasopismo naukowe
Tytuł :
Genome-Wide Characterization and Expression Analysis of NHX Gene Family under Salinity Stress in Gossypium barbadense and Its Comparison with Gossypium hirsutum .
Autorzy :
Akram U; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Song Y; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Liang C; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Abid MA; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Askari M; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Myat AA; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Abbas M; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Malik W; Genomics Lab, Department of Plant Breeding and Genetics, Faculty of Agricultural Science & Technology, Bahauddin Zakariya University, Multan 60000, Pakistan.
Ali Z; Institute of Plant Breeding and Biotechnology, MNS-University of Agriculture, Multan 60000, Pakistan.
Guo S; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Zhang R; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Meng Z; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
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Źródło :
Genes [Genes (Basel)] 2020 Jul 16; Vol. 11 (7). Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gossypium*/classification
Gossypium*/genetics
Plant Proteins/*genetics
Salt Stress/*genetics
Sodium-Hydrogen Exchangers/*genetics
Amiloride/pharmacology ; Enhancer Elements, Genetic/genetics ; Gene Expression Regulation, Plant/drug effects ; Genome, Plant ; Genome-Wide Association Study ; Multigene Family/genetics ; Phylogeny ; Salt Stress/drug effects ; Sodium-Hydrogen Exchangers/drug effects
Czasopismo naukowe
Tytuł :
Sodium-powered stators of the bacterial flagellar motor can generate torque in the presence of phenamil with mutations near the peptidoglycan-binding region.
Autorzy :
Ishida T; Department of Frontier Bioscience, Hosei University, Tokyo, Japan.
Ito R; Department of Frontier Bioscience, Hosei University, Tokyo, Japan.
Clark J; School of Biotechnology and Biomolecular Science, University of New South Wales, Kensington, NSW, Australia.
Matzke NJ; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Sowa Y; Department of Frontier Bioscience, Hosei University, Tokyo, Japan.; Research Center for Micro-Nano Technology, Hosei University, Tokyo, Japan.
Baker MAB; School of Biotechnology and Biomolecular Science, University of New South Wales, Kensington, NSW, Australia.
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Źródło :
Molecular microbiology [Mol Microbiol] 2019 Jun; Vol. 111 (6), pp. 1689-1699. Date of Electronic Publication: 2019 Apr 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amiloride/*analogs & derivatives
Bacterial Proteins/*physiology
Flagella/*physiology
Peptidoglycan/*metabolism
Sodium/*metabolism
ATP-Binding Cassette Transporters/genetics ; ATP-Binding Cassette Transporters/physiology ; Amiloride/pharmacology ; Bacterial Proteins/genetics ; Escherichia coli/drug effects ; Escherichia coli/genetics ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/physiology ; Molecular Motor Proteins/genetics ; Molecular Motor Proteins/physiology ; Phylogeny ; Point Mutation ; Sodium Channel Blockers ; Sodium Channels ; Torque ; Vibrio alginolyticus/drug effects ; Vibrio alginolyticus/genetics
Czasopismo naukowe
Tytuł :
Exploring the quinone/inhibitor-binding pocket in mitochondrial respiratory complex I by chemical biology approaches.
Autorzy :
Uno S; From the Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.
Kimura H; From the Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.
Murai M; From the Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.
Miyoshi H; From the Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2019 Jan 11; Vol. 294 (2), pp. 679-696. Date of Electronic Publication: 2018 Nov 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amiloride/*chemistry
Benzoquinones/*chemistry
Electron Transport Complex I/*chemistry
Electron Transport Complex I/*metabolism
Mitochondria/*metabolism
Amiloride/chemical synthesis ; Amiloride/metabolism ; Animals ; Benzoquinones/metabolism ; Binding Sites ; Catalysis ; Cattle ; Crystallography, X-Ray ; Electron Transport ; Electron Transport Complex I/antagonists & inhibitors ; Electron Transport Complex I/genetics ; Kinetics ; Mitochondria/chemistry ; Mitochondria/genetics ; Photoaffinity Labels ; Quinone Reductases/chemistry ; Quinone Reductases/genetics ; Quinone Reductases/metabolism ; Ubiquinone/chemistry ; Ubiquinone/metabolism
Czasopismo naukowe
Tytuł :
Epithelial sodium channel blockade and new β-ENaC polymorphisms among normotensive and hypertensive adult Nigerians.
Autorzy :
Elias SO; Department of Physiology, Lagos State University College of Medicine, Lagos, Nigeria.
Sofola OA; Department of Physiology, College of Medicine University of Lagos, Lagos, Nigeria.
Jaja SI; Department of Physiology, College of Medicine University of Lagos, Lagos, Nigeria.
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Źródło :
Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2019; Vol. 41 (2), pp. 144-151. Date of Electronic Publication: 2018 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Amiloride/*pharmacology
Blood Pressure/*drug effects
Epithelial Sodium Channel Blockers/*pharmacology
Epithelial Sodium Channels/*genetics
Hypertension/*drug therapy
Hypertension/*genetics
Adult ; Amiloride/therapeutic use ; Case-Control Studies ; Epithelial Sodium Channel Blockers/therapeutic use ; Humans ; Hypertension/physiopathology ; Nigeria ; Polymorphism, Genetic ; Sodium/blood ; Sodium Chloride, Dietary/pharmacology
Czasopismo naukowe

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