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Wyświetlanie 61-80 z 3727
Tytuł:
Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification.
Autorzy:
Dionisi M; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Ruffinatti FA; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Riva B; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Lim D; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Canta A; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, 20900 Monza, Italy.
Meregalli C; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, 20900 Monza, Italy.
Fumagalli G; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, 20900 Monza, Italy.
Monza L; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, 20900 Monza, Italy.
Ferrer-Montiel A; Biología Molecular y Celular, Universidad Miguel Hernández de Elche, 03202 Elche (Alicante), Spain.
Fernandez-Carvajal A; Biología Molecular y Celular, Universidad Miguel Hernández de Elche, 03202 Elche (Alicante), Spain.
Cavaletti G; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, 20900 Monza, Italy.
Genazzani AA; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Distasi C; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Sep 28; Vol. 21 (19). Date of Electronic Publication: 2020 Sep 28.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*adverse effects
Ganglia, Spinal/*drug effects
Neurons/*drug effects
Oxaliplatin/*adverse effects
Peripheral Nervous System Diseases/*genetics
Potassium Channels, Tandem Pore Domain/*genetics
Sodium-Hydrogen Exchanger 1/*genetics
Action Potentials/drug effects ; Action Potentials/physiology ; Amiloride/pharmacology ; Animals ; Capsaicin/pharmacology ; Epithelial Sodium Channel Blockers/pharmacology ; Ganglia, Spinal/metabolism ; Ganglia, Spinal/pathology ; Humans ; Hydrogen-Ion Concentration/drug effects ; Male ; Mice ; Mice, Inbred BALB C ; Models, Biological ; Neurons/metabolism ; Neurons/pathology ; Patch-Clamp Techniques ; Peripheral Nervous System Diseases/chemically induced ; Peripheral Nervous System Diseases/metabolism ; Peripheral Nervous System Diseases/pathology ; Potassium Channels, Tandem Pore Domain/agonists ; Potassium Channels, Tandem Pore Domain/metabolism ; Primary Cell Culture ; Sodium-Hydrogen Exchanger 1/antagonists & inhibitors ; Sodium-Hydrogen Exchanger 1/metabolism ; Transcriptional Activation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Understanding SARS-CoV-2 endocytosis for COVID-19 drug repurposing.
Autorzy:
Glebov OO; Institute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, Shandong, China.; Department of Old Age Psychiatry, The Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England, UK.
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Źródło:
The FEBS journal [FEBS J] 2020 Sep; Vol. 287 (17), pp. 3664-3671. Date of Electronic Publication: 2020 Jun 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Drug Repositioning*
COVID-19 Drug Treatment*
Antiviral Agents/*pharmacology
Endocytosis/*drug effects
SARS-CoV-2/*drug effects
Virus Internalization/*drug effects
Alveolar Epithelial Cells/drug effects ; Alveolar Epithelial Cells/virology ; Amiloride/pharmacology ; COVID-19/metabolism ; COVID-19/pathology ; COVID-19/virology ; Caveolae/drug effects ; Caveolae/virology ; Chlorpromazine/pharmacology ; Clathrin-Coated Vesicles/drug effects ; Clathrin-Coated Vesicles/virology ; Endosomes/drug effects ; Endosomes/virology ; Humans ; Itraconazole/pharmacology ; Lung/drug effects ; Lung/metabolism ; Lung/pathology ; Lung/virology ; Lysosomes/drug effects ; Lysosomes/virology ; Nystatin/pharmacology ; Pinocytosis/drug effects ; SARS-CoV-2/metabolism ; SARS-CoV-2/pathogenicity ; Vinblastine/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ameliorative Effect of Rutin against Zirconium Oxide (ZrO2) Nanoparticle induced Behavioural, Biochemical and Tissue Morphological Changes in Danio rerio.
Autorzy:
Premnath, Briska Jifrina
Pratima, Bichandarkoil Jayaram
Ravichandiran, Ragunath
Srinivasan, Manoj Kumar
Nalini, Namasivayam
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Temat:
ZEBRA danio
ZIRCONIUM oxide
NANOPARTICLES
RUTIN
METAL nanoparticles
AMILORIDE
Źródło:
Pharmacognosy Research; Oct-Dec2023, Vol. 15 Issue 4, p785-795, 11p
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Salt-Stress-Induced Ion Transport Contributes to K + /Na + Homeostasis in Roots of Ping'ou Hybrid Hazelnut.
Autorzy:
Luo, Da
Song, Fenghui
Lu, Mingyan
Shi, Yanjiang
Ma, Qinghua
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Temat:
ION transport (Biology)
EFFECT of salt on plants
SODIUM channels
POTASSIUM channels
HAZELNUTS
AMILORIDE
SOIL salinization
HALOPHYTES
HOMEOSTASIS
Źródło:
Forests (19994907); Aug2023, Vol. 14 Issue 8, p1651, 14p
Terminy geograficzne:
XINJIANG Uygur Zizhiqu (China)
CHINA
Czasopismo naukowe
Szczegóły
Tytuł:
Slc4a11 disruption causes duct cell loss and impairs NaCl reabsorption in female mouse submandibular glands.
Autorzy:
Yang NY; Secretory Mechanisms and Dysfunctions Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.; Department of Pediatric Dentistry, Beijing Stomatological Hospital & School of Stomatology, Capital Medical University, Beijing, China.
Mukaibo T; Secretory Mechanisms and Dysfunctions Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.; Division of Oral Reconstruction and Rehabilitation, Kyushu Dental University, Kitakyushu, Fukuoka, Japan.
Gao X; Secretory Mechanisms and Dysfunctions Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.
Kurtz I; Department of Medicine, Division of Nephrology, David Geffen School of Medicine, and the Brain Research Institute, University of California, Los Angeles, California.
Melvin JE; Secretory Mechanisms and Dysfunctions Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.
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Źródło:
Physiological reports [Physiol Rep] 2019 Dec; Vol. 7 (23), pp. e14232.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Absorption, Physiological*
Protons*
Anion Transport Proteins/*metabolism
Sodium Chloride/*metabolism
Submandibular Gland/*metabolism
Symporters/*metabolism
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid/pharmacology ; Amiloride/analogs & derivatives ; Amiloride/pharmacology ; Animals ; Anion Transport Proteins/antagonists & inhibitors ; Anion Transport Proteins/genetics ; CHO Cells ; Cells, Cultured ; Cricetinae ; Cricetulus ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Submandibular Gland/cytology ; Symporters/antagonists & inhibitors ; Symporters/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Macropinocytosis dependent entry of Chikungunya virus into human muscle cells.
Autorzy:
Lee CHR; Laboratory of Molecular RNA Virology and Antiviral Strategies, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Mohamed Hussain K; Laboratory of Molecular RNA Virology and Antiviral Strategies, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Chu JJH; Laboratory of Molecular RNA Virology and Antiviral Strategies, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Collaborative and Translational Unit for HFMD Singapore, Singapore, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Aug 26; Vol. 13 (8), pp. e0007610. Date of Electronic Publication: 2019 Aug 26 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Virus Internalization*
Chikungunya Fever/*virology
Chikungunya virus/*physiology
Muscles/*virology
Pinocytosis/*physiology
Amiloride/analogs & derivatives ; Amiloride/pharmacology ; Animals ; Cadaverine/analogs & derivatives ; Cadaverine/pharmacology ; Cell Line ; Cell Survival ; Chikungunya virus/growth & development ; Clathrin/antagonists & inhibitors ; Endocytosis/drug effects ; Filipin/pharmacology ; Gene Knockdown Techniques ; Humans ; Hydrazones/pharmacology ; Kinetics ; Pinocytosis/drug effects ; Pinocytosis/genetics ; RNA, Small Interfering ; Rhabdomyosarcoma ; Sorting Nexins/genetics ; Viral Load ; Viral Plaque Assay
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Blockade of the forward Na -mediated cell death.
Autorzy:
Hu HJ; Department of Pharmacology and Chemical Biology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang SS; Department of Pharmacology and Chemical Biology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang YX; Department of Pharmacology and Chemical Biology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liu Y; Department of Pharmacology and Chemical Biology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Feng XM; Department of Pharmacology and Chemical Biology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shen Y; Department of Pharmacology and Chemical Biology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhu L; Department of Pharmacology and Chemical Biology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chen HZ; Department of Pharmacology and Chemical Biology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Song M; Department of Pharmacology and Chemical Biology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2019 Aug; Vol. 176 (15), pp. 2691-2707. Date of Electronic Publication: 2019 Jun 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacology
Antineoplastic Agents/*therapeutic use
Bepridil/*pharmacology
Bepridil/*therapeutic use
Calcium/*metabolism
Glioblastoma/*drug therapy
Sodium-Calcium Exchanger/*antagonists & inhibitors
Amiloride/analogs & derivatives ; Amiloride/pharmacology ; Aniline Compounds/pharmacology ; Animals ; Astrocytes/drug effects ; Benzyl Compounds/pharmacology ; Cell Cycle/drug effects ; Cell Death/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Glioblastoma/metabolism ; Humans ; Male ; Mice, Inbred BALB C ; Mice, Nude ; Mitogen-Activated Protein Kinases/metabolism ; Niacinamide/analogs & derivatives ; Niacinamide/pharmacology ; Phenyl Ethers/pharmacology ; Sodium-Calcium Exchanger/physiology ; Thiazolidines/pharmacology ; Thiourea/analogs & derivatives ; Thiourea/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of amiloride on endoplasmic reticulum stress response in the injured spinal cord of rats.
Autorzy:
Kuroiwa M; Department of Orthopaedic Surgery, Surgical Science, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Watanabe M
Katoh H
Suyama K
Matsuyama D
Imai T
Mochida J
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2014 Oct; Vol. 40 (7), pp. 3120-7. Date of Electronic Publication: 2014 Jun 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amiloride/*therapeutic use
Endoplasmic Reticulum Stress/*drug effects
Neuroprotective Agents/*therapeutic use
Recovery of Function/*drug effects
Spinal Cord Injuries/*drug therapy
Spinal Cord Injuries/*metabolism
Amiloride/pharmacology ; Animals ; Apoptosis/drug effects ; Cells, Cultured ; Female ; Heat-Shock Proteins/metabolism ; Neuroprotective Agents/pharmacology ; Oligodendroglia/drug effects ; Oligodendroglia/metabolism ; Rats ; Rats, Sprague-Dawley ; Thoracic Vertebrae
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A cell-permeant amiloride derivative induces caspase-independent, AIF-mediated programmed necrotic death of breast cancer cells.
Autorzy:
Leon LJ; Department of Biochemistry and Molecular Medicine, UC Davis School of Medicine, Sacramento, California, United States of America.
Pasupuleti N
Gorin F
Carraway KL 3rd
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Źródło:
PloS one [PLoS One] 2013 Apr 30; Vol. 8 (4), pp. e63038. Date of Electronic Publication: 2013 Apr 30 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Cell Membrane Permeability*
Amiloride/*analogs & derivatives
Amiloride/*pharmacology
Apoptosis/*drug effects
Apoptosis Inducing Factor/*metabolism
Breast Neoplasms/*metabolism
Caspases/*metabolism
Glycine/*analogs & derivatives
Amiloride/chemistry ; Amiloride/toxicity ; Calcium/metabolism ; Calpain/metabolism ; Cell Cycle/drug effects ; Cell Death/drug effects ; Cell Line, Tumor ; Cell Nucleus/metabolism ; Endoplasmic Reticulum/drug effects ; Endoplasmic Reticulum/ultrastructure ; Female ; Glycine/chemistry ; Glycine/pharmacology ; Glycine/toxicity ; Humans ; Protein Transport
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Pyrazine ring-based Na exchanger (NHE) inhibitors potently inhibit cancer cell growth in 3D culture, independent of NHE1.
Autorzy:
Rolver MG; Section for Cell Biology and Physiology, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Elingaard-Larsen LO; Section for Cell Biology and Physiology, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Andersen AP; Center for Medical Parasitology, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Counillon L; Université Côte d'Azur, CNRS, France LP2M, 28 Avenue de Valombrose, and Laboratories of Excellence Ion Channel Science and Therapeutics, Nice, France.
Pedersen SF; Section for Cell Biology and Physiology, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark. .
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Źródło:
Scientific reports [Sci Rep] 2020 Apr 02; Vol. 10 (1), pp. 5800. Date of Electronic Publication: 2020 Apr 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amiloride/*pharmacology
Antineoplastic Agents/*pharmacology
Guanidines/*pharmacology
Spheroids, Cellular/*drug effects
Sulfones/*pharmacology
Apoptosis ; Autophagy ; Cell Proliferation ; Endoplasmic Reticulum Stress ; Humans ; MCF-7 Cells ; Neoplasms/metabolism ; Sodium-Hydrogen Exchanger 1/genetics ; Sodium-Hydrogen Exchanger 1/metabolism ; Spheroids, Cellular/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Urokinase-type plasminogen activator contributes to amiloride-sensitive sodium retention in nephrotic range glomerular proteinuria in mice.
Autorzy:
Hinrichs GR; Department of Molecular Medicine, Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark.
Weyer K; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Friis UG; Department of Molecular Medicine, Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark.
Svenningsen P; Department of Molecular Medicine, Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark.
Lund IK; The Finsen Laboratory, Rigshospitalet, Copenhagen, Denmark.; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.
Nielsen R; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Mollet G; Laboratory of Hereditary Kidney Diseases, Imagine Institute, Inserm, U1163, Paris Descartes-Sorbonne Paris Cité University, Paris, France.
Antignac C; Laboratory of Hereditary Kidney Diseases, Imagine Institute, Inserm, U1163, Paris Descartes-Sorbonne Paris Cité University, Paris, France.; Department of Genetics, Necker Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Bistrup C; Department of Nephrology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Jensen BL; Department of Molecular Medicine, Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark.
Birn H; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Department of Renal Medicine, Aarhus University Hospital, Aarhus, Denmark.
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Źródło:
Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2019 Dec; Vol. 227 (4), pp. e13362. Date of Electronic Publication: 2019 Sep 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amiloride/*pharmacology
Kidney Glomerulus/*metabolism
Nephrotic Syndrome/*metabolism
Proteinuria/*metabolism
Sodium/*metabolism
Animals ; Epithelial Sodium Channel Blockers/pharmacology ; Gene Expression Regulation/drug effects ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; Mice, Knockout ; Peptide Hydrolases/urine ; Plasminogen/urine ; Urokinase-Type Plasminogen Activator ; Water/metabolism ; Weight Loss/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of the Heterogeneous Distribution of Amiloride and Propranolol in Dried Blood Spot by UHPLC-FLD and MALDI-IMS.
Autorzy:
Uribe B; Analytical Chemistry Department, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Sarriena s/n, 48940 Leioa, Biscay, Basque Country, Spain.
González O; Analytical Chemistry Department, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Sarriena s/n, 48940 Leioa, Biscay, Basque Country, Spain.
Blanco ME; Analytical Chemistry Department, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Sarriena s/n, 48940 Leioa, Biscay, Basque Country, Spain.
Albóniga OE; Analytical Chemistry Department, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Sarriena s/n, 48940 Leioa, Biscay, Basque Country, Spain.
Alonso ML; Analytical Chemistry Department, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Sarriena s/n, 48940 Leioa, Biscay, Basque Country, Spain.
Alonso RM; Analytical Chemistry Department, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Sarriena s/n, 48940 Leioa, Biscay, Basque Country, Spain.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2019 Nov 26; Vol. 24 (23). Date of Electronic Publication: 2019 Nov 26.
Typ publikacji:
Journal Article
MeSH Terms:
Amiloride/*metabolism
Propranolol/*metabolism
Blood Specimen Collection/methods ; Chromatography, High Pressure Liquid/methods ; Dried Blood Spot Testing/methods ; Hematocrit/methods ; Humans ; Limit of Detection ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods ; Tandem Mass Spectrometry/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genome-wide identification and expression analysis of the NHX gene family under salt stress in wheat (Triticum aestivum L)
Autorzy:
Pradeep Sharma
Shefali Mishra
Bharati Pandey
Gyanendra Singh
Pokaż więcej
Temat:
Na +/H + antiporter
amiloride-binding site
molecular dynamics
gene expression
salt stress
wheat
Plant culture
SB1-1110
Źródło:
Frontiers in Plant Science, Vol 14 (2023)
Opis pliku:
electronic resource
Relacje:
https://www.frontiersin.org/articles/10.3389/fpls.2023.1266699/full; https://doaj.org/toc/1664-462X
Dostęp URL:
https://doaj.org/article/dcab81dc40974041b010996103c7e9e7  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Vps34-mediated macropinocytosis in Tuberous Sclerosis Complex 2-deficient cells supports tumorigenesis.
Autorzy:
Filippakis H; Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. .
Belaid A; Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Siroky B; Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Wu C; Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Alesi N; Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Hougard T; Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Nijmeh J; Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Lam HC; Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Henske EP; Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. .
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Źródło:
Scientific reports [Sci Rep] 2018 Sep 21; Vol. 8 (1), pp. 14161. Date of Electronic Publication: 2018 Sep 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinogenesis/*metabolism
Class III Phosphatidylinositol 3-Kinases/*metabolism
Pinocytosis/*physiology
Tuberous Sclerosis/*metabolism
Amiloride/analogs & derivatives ; Amiloride/pharmacology ; Animals ; Autophagy/drug effects ; Autophagy/physiology ; Autophagy-Related Protein 5/metabolism ; Carcinogenesis/drug effects ; Cell Line ; Cell Proliferation/drug effects ; Cell Proliferation/physiology ; Dextrans/metabolism ; Down-Regulation/drug effects ; Down-Regulation/physiology ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Pinocytosis/drug effects ; Protein Kinase Inhibitors/pharmacology ; Tuberous Sclerosis Complex 2 Protein/deficiency ; Tuberous Sclerosis Complex 2 Protein/metabolism ; Up-Regulation/drug effects ; Up-Regulation/physiology
SCR Disease Name:
Tuberous Sclerosis 2
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of Antihypertensive Treatment on Left and Right Ventricular Global Longitudinal Strain and Diastolic Parameters in Patients with Hypertension and Obstructive Sleep Apnea: Randomized Clinical Trial of Chlorthalidone plus Amiloride vs. Amlodipine †
Autorzy:
Jorge, Juliano A.
Foppa, Murilo
Santos, Angela B. S.
Cichelero, Fábio T.
Martinez, Denis
Lucca, Marcelo B.
de Oliveira, Geórgia P. F.
Fuchs, Flávio D.
Fuchs, Sandra C.
Pokaż więcej
Temat:
GLOBAL longitudinal strain
SLEEP apnea syndromes
CLINICAL trials
RIGHT ventricular hypertrophy
HYPERTENSION
RENOVASCULAR hypertension
AMILORIDE
AMBULATORY blood pressure monitoring
Źródło:
Journal of Clinical Medicine; Jun2023, Vol. 12 Issue 11, p3785, 10p
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 61-80 z 3727

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