Temat: "Amiloride" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The Epithelial Sodium Channel-An Underestimated Drug Target.
Autorzy:: Lemmens-Gruber R; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, A-1090 Vienna, Austria.
Tzotzos S; Independent Researcher, A-1180 Vienna, Austria.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 24; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 24.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Hypertension*/metabolism
Liddle Syndrome*
Pseudohypoaldosteronism*/metabolism
Animals ; Epithelial Sodium Channels/genetics ; Epithelial Sodium Channels/metabolism ; Amiloride/pharmacology

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Skocz do pozycji: 2.

Tytuł:: Lipid Profiles of Urinary Extracellular Vesicles Released during the Inactive and Active Phases of Aged Male Mice with Spontaneous Hypertension.
Autorzy:: Lopez JP; Department of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Nouri MZ; Department of Physiological Sciences and Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL 32611, USA.
Ebrahim A; Department of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Chacko KM; Department of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Schramm WC; Department of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Gholam MF; Department of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, USA.; Department of Basic Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Jeddah 21423, Saudi Arabia.
Ozrazgat-Baslanti T; Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Denslow ND; Department of Physiological Sciences and Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL 32611, USA.
Alli AA; Department of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, USA.; Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, College of Medicine, University of Florida, Gainesville, FL 32610, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Dec 06; Vol. 23 (23). Date of Electronic Publication: 2022 Dec 06.
Typ publikacji:: Journal Article
MeSH Terms:: Hypertension*/metabolism
Extracellular Vesicles*/metabolism
Mice ; Male ; Animals ; Epithelial Sodium Channels/metabolism ; Kidney/metabolism ; Amiloride/pharmacology ; Lipids

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Skocz do pozycji: 3.

Tytuł:: Efficacy of chlorthalidone and hydrochlorothiazide in combination with amiloride in multiple doses on blood pressure in patients with primary hypertension: a protocol for a factorial randomized controlled trial.
Autorzy:: Martins VM; Graduate Program in Cardiology and Cardiovascular Sciences, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. .
Helal L; Graduate Program in Cardiology and Cardiovascular Sciences, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Ferrari F; Graduate Program in Cardiology and Cardiovascular Sciences, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Bottino LG; Graduate Program in Cardiology and Cardiovascular Sciences, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Fuchs SC; Graduate Program in Cardiology and Cardiovascular Sciences, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Fuchs FD; Graduate Program in Cardiology and Cardiovascular Sciences, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.; Division of Cardiology, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.; Pokaż więcej
Źródło:: Trials [Trials] 2019 Dec 16; Vol. 20 (1), pp. 736. Date of Electronic Publication: 2019 Dec 16.
Typ publikacji:: Clinical Trial Protocol; Journal Article
MeSH Terms:: Amiloride/*administration & dosage
Antihypertensive Agents/*administration & dosage
Blood Pressure/*drug effects
Chlorthalidone/*administration & dosage
Hydrochlorothiazide/*administration & dosage
Hypertension/*drug therapy
Sodium Chloride Symporter Inhibitors/*administration & dosage
Amiloride/adverse effects ; Antihypertensive Agents/adverse effects ; Brazil ; Chlorthalidone/adverse effects ; Double-Blind Method ; Drug Combinations ; Humans ; Hydrochlorothiazide/adverse effects ; Hypertension/diagnosis ; Hypertension/physiopathology ; Randomized Controlled Trials as Topic ; Sodium Chloride Symporter Inhibitors/adverse effects ; Time Factors ; Treatment Outcome

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Skocz do pozycji: 4.

Tytuł:: Epithelial sodium channel blockade and new β-ENaC polymorphisms among normotensive and hypertensive adult Nigerians.
Autorzy:: Elias SO; Department of Physiology, Lagos State University College of Medicine, Lagos, Nigeria.
Sofola OA; Department of Physiology, College of Medicine University of Lagos, Lagos, Nigeria.
Jaja SI; Department of Physiology, College of Medicine University of Lagos, Lagos, Nigeria.; Pokaż więcej
Źródło:: Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2019; Vol. 41 (2), pp. 144-151. Date of Electronic Publication: 2018 Mar 26.
Typ publikacji:: Journal Article
MeSH Terms:: Amiloride/*pharmacology
Blood Pressure/*drug effects
Epithelial Sodium Channel Blockers/*pharmacology
Epithelial Sodium Channels/*genetics
Hypertension/*drug therapy
Hypertension/*genetics
Adult ; Amiloride/therapeutic use ; Case-Control Studies ; Epithelial Sodium Channel Blockers/therapeutic use ; Humans ; Hypertension/physiopathology ; Nigeria ; Polymorphism, Genetic ; Sodium/blood ; Sodium Chloride, Dietary/pharmacology

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Skocz do pozycji: 5.

Tytuł:: The importance of the epithelial sodium channel in determining salt sensitivity in people of African origin.
Autorzy:: Jones E; Division of Nephrology and Hypertension, University of Cape Town, Cape Town, South Africa.
Rayner B; Division of Nephrology and Hypertension, University of Cape Town, Cape Town, South Africa. .; E13 Groote Schuur Hospital, Observatory, Cape Town, 7925, South Africa. .; Pokaż więcej
Źródło:: Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2021 Feb; Vol. 36 (2), pp. 237-243. Date of Electronic Publication: 2020 Jan 02.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Hypertension*/diagnosis
Hypertension*/drug therapy
Aldosterone ; Amiloride ; Blood Pressure ; Epithelial Sodium Channels ; Humans ; Sodium/metabolism ; Sodium Chloride, Dietary/adverse effects

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Skocz do pozycji: 6.

Tytuł:: ENaC blockade in proteinuria-associated extracellular fluid volume overload - effective but risky.
Autorzy:: Ray EC; Renal-Electrolyte Division, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.; Pokaż więcej
Źródło:: Physiological reports [Physiol Rep] 2018 Sep; Vol. 6 (17), pp. e13835.
Typ publikacji:: Editorial; Research Support, N.I.H., Extramural; Comment
MeSH Terms:: Hypertension*
Nephrotic Syndrome*
Amiloride ; Edema ; Extracellular Fluid ; Humans ; Proteinuria

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Skocz do pozycji: 7.

Tytuł:: Amiloride resolves resistant edema and hypertension in a patient with nephrotic syndrome; a case report.
Autorzy:: Hinrichs GR; Department of Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark.
Mortensen LA; Department of Nephrology, Odense University Hospital, Odense, Denmark.
Jensen BL; Department of Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark.
Bistrup C; Department of Nephrology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Pokaż więcej
Źródło:: Physiological reports [Physiol Rep] 2018 Jun; Vol. 6 (12), pp. e13743.
Typ publikacji:: Case Reports; Research Support, Non-U.S. Gov't
MeSH Terms:: Amiloride/*therapeutic use
Diuretics/*therapeutic use
Edema/*drug therapy
Hypertension/*drug therapy
Nephrotic Syndrome/*drug therapy
Adult ; Antihypertensive Agents/therapeutic use ; Diabetic Nephropathies/drug therapy ; Drug Therapy, Combination ; Epithelial Sodium Channel Blockers/therapeutic use ; Humans ; Male

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Skocz do pozycji: 8.

Tytuł:: A comparison between diuretics and angiotensin-receptor blocker agents in patients with stage I hypertension (PREVER-treatment trial): study protocol for a randomized double-blind controlled trial.
Autorzy:: Fuchs FD; Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. />Fuchs SC
Moreira LB
Gus M
Nóbrega AC
Poli-de-Figueiredo CE
Mion D
Bortolotto L
Consolim-Colombo F
Nobre F
Coelho EB
Vilela-Martin JF
Moreno H Jr
Cesarino EJ
Franco R
Brandão AA
de Sousa MR
Ribeiro AL
Jardim PC
Afiune Neto A
Scala LC
Mota M
Chaves H
Alves JG
Sobral Filho DC
Pereira e Silva R
Figueiredo Neto JA
Irigoyen MC
Castro I
Steffens AA
Schlatter R
de Mello RB
Mosele F
Ghizzoni F
Berwanger O; Pokaż więcej
Źródło:: Trials [Trials] 2011 Feb 24; Vol. 12, pp. 53. Date of Electronic Publication: 2011 Feb 24.
Typ publikacji:: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:: Research Design*
Amiloride/*therapeutic use
Angiotensin II Type 1 Receptor Blockers/*therapeutic use
Antihypertensive Agents/*therapeutic use
Blood Pressure/*drug effects
Chlorthalidone/*therapeutic use
Diuretics/*therapeutic use
Hypertension/*drug therapy
Losartan/*therapeutic use
Adult ; Aged ; Amiloride/adverse effects ; Angiotensin II Type 1 Receptor Blockers/adverse effects ; Antihypertensive Agents/adverse effects ; Brazil ; Chlorthalidone/adverse effects ; Diuretics/adverse effects ; Double-Blind Method ; Drug Therapy, Combination ; Female ; Humans ; Hypertension/physiopathology ; Losartan/adverse effects ; Male ; Middle Aged ; Severity of Illness Index ; Time Factors ; Treatment Outcome

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Skocz do pozycji: 9.

Tytuł:: A role for benzamil-sensitive proteins of the central nervous system in the pathogenesis of salt-dependent hypertension.
Autorzy:: Abrams JM; Graduate Program in Neuroscience, Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Osborn JW; Pokaż więcej
Źródło:: Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2008 May; Vol. 35 (5-6), pp. 687-94.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Amiloride/*analogs & derivatives
Central Nervous System/*drug effects
Central Nervous System/*metabolism
Hypertension/*drug therapy
Hypertension/*metabolism
Sodium Channel Blockers/*pharmacology
Sodium Chloride/*toxicity
Amiloride/pharmacology ; Humans

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Skocz do pozycji: 10.

Tytuł:: Drug effects on the CVS in conscious rats: separating cardiac output into heart rate and stroke volume using PKPD modelling.
Autorzy:: Snelder N; Division of Pharmacology, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden, The Netherlands.
Ploeger BA
Luttringer O
Rigel DF
Fu F
Beil M
Stanski DR
Danhof M; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2014 Nov; Vol. 171 (22), pp. 5076-92. Date of Electronic Publication: 2014 Sep 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Models, Biological*
Hemodynamics/*drug effects
Hypertension/*metabolism
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/analogs & derivatives ; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/pharmacokinetics ; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/pharmacology ; Amiloride/pharmacokinetics ; Amiloride/pharmacology ; Amlodipine/pharmacokinetics ; Amlodipine/pharmacology ; Animals ; Atropine/pharmacokinetics ; Atropine/pharmacology ; Enalapril/pharmacokinetics ; Enalapril/pharmacology ; Hydrochlorothiazide/pharmacokinetics ; Hydrochlorothiazide/pharmacology ; Male ; Prazosin/pharmacokinetics ; Prazosin/pharmacology ; Propranolol/pharmacokinetics ; Propranolol/pharmacology ; Rats, Inbred SHR ; Rats, Inbred WKY

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Skocz do pozycji: 11.

Tytuł:: [Hypertension in the course of primary aldosteronism during pregnancy].
Autorzy:: Wyskida M; Zakład Patofizjologii Katedry Patofizjologii Wydziału Lekarskiego w Katowicach Śląskiego Uniwersytetu Medycznego w Katowicach.
Wyskida K; Zakład Promocji Zdrowia i Leczenia Otyłości Katedry Patofizjologii Wydziału Lekarskiego w Katowicach Śląskiego Uniwersytetu Medycznego w Katowicach.
Olszanecka-Glinianowicz M; Zakład Promocji Zdrowia i Leczenia Otyłości Katedry Patofizjologii Wydziału Lekarskiego w Katowicach Śląskiego Uniwersytetu Medycznego w Katowicach.
Maruniak-Chudek I; Klinika Intensywnej Terapii i Patologii Noworodka Katedry Pediatrii Wydziału Lekarskiego w Katowicach Śląskiego Uniwersytetu Medycznego w Katowicach.
Sikora J; Katedra i Klinika Perinatologii i Ginekologii Wydziału Nauk o Zdrowiu Śląskiego Uniwersytetu Medycznego w Katowicach.
Chudek J; Zakład Patofizjologii Katedry Patofizjologii Wydziału Lekarskiego w Katowicach Śląskiego Uniwersytetu Medycznego w Katowicach.; Pokaż więcej
Transliterated Title:: Nadciśnienie tętnicze w przebiegu pierwotnego hiperaldosteronizmu u kobiet w ciąży
Źródło:: Postepy higieny i medycyny doswiadczalnej (Online) [Postepy Hig Med Dosw (Online)] 2015 Feb 15; Vol. 69, pp. 207-13. Date of Electronic Publication: 2015 Feb 15.
Typ publikacji:: Journal Article; Review; Systematic Review
MeSH Terms:: Hyperaldosteronism/*diagnosis
Hyperaldosteronism/*drug therapy
Hypertension/*diagnosis
Hypertension/*drug therapy
Pregnancy Complications/*diagnosis
Pregnancy Complications/*drug therapy
Acid Sensing Ion Channel Blockers/therapeutic use ; Aldosterone/metabolism ; Amiloride/therapeutic use ; Antihypertensive Agents/therapeutic use ; Eplerenone ; Female ; Humans ; Poland ; Pregnancy ; Progesterone/therapeutic use ; Spironolactone/analogs & derivatives ; Spironolactone/therapeutic use