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Wyszukujesz frazę ""Amino Acid Sequence"" wg kryterium: Temat


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Tytuł :
PINIR: a comprehensive information resource for Pin-II type protease inhibitors.
Autorzy :
Yadav NK; Publication and Science Communication Unit, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, 411008, India.; Information Systems Area, Indian Institute of Management Indore, Indore, 453556, India.
Saikhedkar NS; Biochemical Sciences Division, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, 411008, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Giri AP; Biochemical Sciences Division, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, 411008, India. .; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. .
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Źródło :
BMC plant biology [BMC Plant Biol] 2021 Jun 09; Vol. 21 (1), pp. 267. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article
MeSH Terms :
Amino Acid Sequence*
Databases as Topic*
Genes, Plant*
Disease Resistance/*genetics
Plant Proteins/*genetics
Serine Proteinase Inhibitors/*genetics
Czasopismo naukowe
Tytuł :
An Ensemble Learning-Based Method for Inferring Drug-Target Interactions Combining Protein Sequences and Drug Fingerprints.
Autorzy :
Zhao ZY; School of Information Engineering, Xijing University, Xi'an 710123, China.
Huang WZ; School of Information Engineering, Xijing University, Xi'an 710123, China.
Zhan XK; School of Information Engineering, Xijing University, Xi'an 710123, China.
Pan J; School of Information Engineering, Xijing University, Xi'an 710123, China.
Huang YA; School of Information Engineering, Xijing University, Xi'an 710123, China.
Zhang SW; School of Information Engineering, Xijing University, Xi'an 710123, China.
Yu CQ; School of Information Engineering, Xijing University, Xi'an 710123, China.
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Źródło :
BioMed research international [Biomed Res Int] 2021 Apr 24; Vol. 2021, pp. 9933873. Date of Electronic Publication: 2021 Apr 24 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Amino Acid Sequence*
Drug Interactions*
Machine Learning*
Computational Biology/*methods
Drug Discovery/*methods
Databases, Protein ; Position-Specific Scoring Matrices ; Support Vector Machine
Czasopismo naukowe
Tytuł :
Two Siblings Homozygous for F508del-CFTR Have Varied Disease Phenotypes and Protein Biomarkers.
Autorzy :
Zhang Z; Department of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Wang J; Department of Microbiology, Immunology, and Biochemistry, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Zhang YH; Department of Bioscience Research, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Gardner TE; Department of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.; University of Tennessee Cystic Fibrosis Care and Research Center at Le Bonheur Children's Hospital-Methodist University Hospital, Memphis, TN 38103, USA.
Fitzpatrick EA; Department of Microbiology, Immunology, and Biochemistry, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Zhang W; Department of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.; University of Tennessee Cystic Fibrosis Care and Research Center at Le Bonheur Children's Hospital-Methodist University Hospital, Memphis, TN 38103, USA.; Departments of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.; Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN 38103, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 05; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Case Reports
MeSH Terms :
Amino Acid Sequence*
Cystic Fibrosis*/genetics
Cystic Fibrosis*/metabolism
Homozygote*
Sequence Deletion*
Siblings*
Cystic Fibrosis Transmembrane Conductance Regulator/*genetics
Inflammation Mediators/*metabolism
T-Lymphocytes, Helper-Inducer/*metabolism
Biomarkers/metabolism ; Female ; Humans ; Leukocyte Elastase/metabolism ; Male ; Sputum/metabolism
Raport
Tytuł :
Nucleation-dependent Aggregation Kinetics of Yeast Sup35 Fragment GNNQQNY.
Autorzy :
Burra G; Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, India; Sussex Neuroscience, School of Life Sciences, University of Sussex, UK. Electronic address: .
Maina MB; Sussex Neuroscience, School of Life Sciences, University of Sussex, UK; College of Medical Sciences, Yobe State University, Nigeria.
Serpell LC; Sussex Neuroscience, School of Life Sciences, University of Sussex, UK.
Thakur AK; Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, India. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Feb 05; Vol. 433 (3), pp. 166732. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amino Acid Sequence*
Protein Aggregates*
Yeasts*/metabolism
Fungal Proteins/*chemistry
Fungal Proteins/*metabolism
Peptide Fragments/*chemistry
Amyloid/metabolism ; Amyloidogenic Proteins/chemistry ; Amyloidogenic Proteins/metabolism ; Cell Survival ; Fluorescent Antibody Technique ; Kinetics ; Peptide Fragments/metabolism ; Protein Transport ; Solubility ; Spectrum Analysis ; Thermodynamics
Czasopismo naukowe
Tytuł :
Using bioinformatic protein sequence similarity to investigate if SARS CoV-2 infection could cause an ocular autoimmune inflammatory reactions?
Autorzy :
Karagöz IK; Ümraniye Trn. And Rch. Hospital, Division of Ophthalmology, Istanbul, Turkey. Electronic address: .
Munk MR; Dept. of Ophthalmology and Bern Photographic Reading Center (BPRC), University of Bern, Bern, Switzerland.
Kaya M; Diagen Biotechnology, Ankara, Turkey.
Rückert R; Eyegnos Consulting GmbH, Bern, Switzerland.
Yıldırım M; Bahçeşehir University, Internal Diseases, Division of Oncology, Istanbul, Turkey.
Karabaş L; Kocaeli University School of Medicine, Ophthalmology Department, Izmit-Kocaeli, Turkey.
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Źródło :
Experimental eye research [Exp Eye Res] 2021 Feb; Vol. 203, pp. 108433. Date of Electronic Publication: 2021 Jan 02.
Typ publikacji :
Journal Article
MeSH Terms :
Amino Acid Sequence*
Sequence Homology*
Autoimmune Diseases/*virology
Eye Proteins/*chemistry
Retinal Diseases/*virology
SARS-CoV-2/*chemistry
Viral Proteins/*chemistry
COVID-19/epidemiology ; Computational Biology ; Coronavirus Envelope Proteins/chemistry ; Coronavirus Nucleocapsid Proteins/chemistry ; Eye Infections, Viral/virology ; Humans ; Membrane Glycoproteins/chemistry ; Phosphoproteins/chemistry ; Polyproteins/chemistry ; Retinal Pigment Epithelium/chemistry ; Viral Matrix Proteins/chemistry
Czasopismo naukowe
Tytuł :
Investigation of the Role of Aromatic Residues in the Antimicrobial Peptide BuCATHL4B.
Autorzy :
Necelis MR; Department of Chemistry and Biochemistry, Rowan University, Glassboro, NJ, United States.
Santiago-Ortiz LE; Department of Biological Sciences, Rowan University, Glassboro NJ, United States.
Caputo GA; Department of Chemistry and Biochemistry, Rowan University, Glassboro, NJ, United States.
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Źródło :
Protein and peptide letters [Protein Pept Lett] 2021; Vol. 28 (4), pp. 388-402.
Typ publikacji :
Journal Article
MeSH Terms :
Amino Acid Sequence*
Antimicrobial Cationic Peptides*/chemistry
Antimicrobial Cationic Peptides*/genetics
Antimicrobial Cationic Peptides*/pharmacology
Bacteria/*growth & development
Tryptophan/*chemistry
Lipid Bilayers/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Glycine 236 in the Lower Hinge Region of Human IgG1 Differentiates FcγR from Complement Effector Function.
Autorzy :
Brinkhaus M; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, 1066 CX, Amsterdam, the Netherlands.
Douwes RGJ; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, 1066 CX, Amsterdam, the Netherlands.
Bentlage AEH; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, 1066 CX, Amsterdam, the Netherlands.
Temming AR; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, 1066 CX, Amsterdam, the Netherlands.
de Taeye SW; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, 1066 CX, Amsterdam, the Netherlands.; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, 1066 CX Amsterdam, the Netherlands.
Tammes Buirs M; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, 1066 CX, Amsterdam, the Netherlands.
Gerritsen J; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, 1066 CX, Amsterdam, the Netherlands.
Mok JY; Sanquin Reagents, 1066 CX Amsterdam, the Netherlands.
Brasser G; Sanquin Reagents, 1066 CX Amsterdam, the Netherlands.
Ligthart PC; Sanquin Diagnostic Services, Department of Immunohematology Diagnostics, 1066 CX Amsterdam, the Netherlands; and.
van Esch WJE; Sanquin Reagents, 1066 CX Amsterdam, the Netherlands.
Verheesen P; argenx, 9052 Zwijnaarde, Belgium.
de Haard H; argenx, 9052 Zwijnaarde, Belgium.
Rispens T; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, 1066 CX Amsterdam, the Netherlands.
Vidarsson G; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, 1066 CX, Amsterdam, the Netherlands; .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2020 Dec 15; Vol. 205 (12), pp. 3456-3467. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amino Acid Sequence*
Complement Activation*
Complement C1q*/chemistry
Complement C1q*/genetics
Complement C1q*/immunology
Immunoglobulin G*/chemistry
Immunoglobulin G*/genetics
Immunoglobulin G*/immunology
Receptors, IgG*/chemistry
Receptors, IgG*/genetics
Receptors, IgG*/immunology
Sequence Deletion*
Surface Plasmon Resonance*
Glycine/chemistry ; Glycine/genetics ; Glycine/immunology ; HEK293 Cells ; Humans
Czasopismo naukowe
Tytuł :
Purification, characterization and partial amino acid sequences of thermo-alkali-stable and mercury ion-tolerant xylanase from Thermomyces dupontii KKU-CLD-E2-3.
Autorzy :
Seemakram W; Graduate School, Khon Kaen University, Khon Kaen, 40002, Thailand.
Boonrung S; Biology Program, Faculty of Science, Buriram Rajabhat University, Buriram, 31000, Thailand.
Aimi T; Department of Biochemistry and Biotechnology, Faculty of Agriculture, Tottori University, Tottori, 680-8553, Japan.
Ekprasert J; Department of Microbiology, Faculty of Science, Khon Kaen University, Khon Kaen, 40002, Thailand.; Protein and Proteomics Research Center for Commercial and Industrial Purposes (ProCCI), Faculty of Science, Khon Kaen University, Khon Kaen, 40002, Thailand.
Lumyong S; Department of Biology, Faculty of Science, Chiang Mai Univertity, Chiang Mai, 50200, Thailand.; Research Center of Microbial Diversity and Sustainable Utilization, Chiang Mai University, Chiang Mai, 50200, Thailand.; Academy of Science, The Royal Society of Thailand, Bangkok, 10300, Thailand.
Boonlue S; Department of Microbiology, Faculty of Science, Khon Kaen University, Khon Kaen, 40002, Thailand. .; Protein and Proteomics Research Center for Commercial and Industrial Purposes (ProCCI), Faculty of Science, Khon Kaen University, Khon Kaen, 40002, Thailand. .
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Źródło :
Scientific reports [Sci Rep] 2020 Dec 10; Vol. 10 (1), pp. 21663. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alkalies*
Amino Acid Sequence*
Mercury*
Endo-1,4-beta Xylanases/*chemistry
Endo-1,4-beta Xylanases/*isolation & purification
Eurotiales/*enzymology
Disaccharides ; Enzyme Stability ; Hot Temperature ; Hydrogen-Ion Concentration ; Hydrolysis ; Industry ; Paper ; Substrate Specificity ; Xylans
SCR Organism :
Thermomyces dupontii
Czasopismo naukowe
Tytuł :
Prediction of membrane protein types by fusing protein-protein interaction and protein sequence information.
Autorzy :
Zhang X; College of Information Engineering, Shanghai Maritime University, Shanghai 201306, People's Republic of China.
Chen L; College of Information Engineering, Shanghai Maritime University, Shanghai 201306, People's Republic of China. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Proteins and proteomics [Biochim Biophys Acta Proteins Proteom] 2020 Dec; Vol. 1868 (12), pp. 140524. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amino Acid Sequence*
Computational Biology*/methods
Protein Interaction Mapping*
Protein Interaction Maps*
Membrane Proteins/*chemistry
Membrane Proteins/*metabolism
Algorithms ; Amino Acids ; Databases, Protein ; Humans ; Protein Binding ; Reproducibility of Results ; Support Vector Machine
Czasopismo naukowe
Tytuł :
Ancestral sequence reconstruction produces thermally stable enzymes with mesophilic enzyme-like catalytic properties.
Autorzy :
Furukawa R; Faculty of Human Sciences, Waseda University, 2-579-15 Mikajima, Tokorozawa, Saitama, 359-1192, Japan.
Toma W; Faculty of Human Sciences, Waseda University, 2-579-15 Mikajima, Tokorozawa, Saitama, 359-1192, Japan.
Yamazaki K; Faculty of Human Sciences, Waseda University, 2-579-15 Mikajima, Tokorozawa, Saitama, 359-1192, Japan.
Akanuma S; Faculty of Human Sciences, Waseda University, 2-579-15 Mikajima, Tokorozawa, Saitama, 359-1192, Japan. .
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 23; Vol. 10 (1), pp. 15493. Date of Electronic Publication: 2020 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amino Acid Sequence*/genetics
Amino Acid Sequence*/physiology
Catalysis*
Enzymes/*metabolism
3-Isopropylmalate Dehydrogenase/genetics ; 3-Isopropylmalate Dehydrogenase/metabolism ; Cold Temperature ; Enzyme Stability/genetics ; Enzymes/genetics ; Kinetics ; Phylogeny ; Sequence Alignment ; Temperature ; Thermus thermophilus/enzymology ; Thermus thermophilus/genetics
Czasopismo naukowe
Tytuł :
Better understanding and prediction of antiviral peptides through primary and secondary structure feature importance.
Autorzy :
Chowdhury AS; Biological Sciences Division, Pacific Northwest National Laboratory, J4-18, P.O. Box 999, Richland, WA, 99354, USA.
Reehl SM; Computing and Analytics Division, Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA, 99354, USA.
Kehn-Hall K; School of Systems Biology, George Mason University, Manassas, VA, 20110, USA.; National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA, 20110, USA.; Department of Biomedical Sciences and Pathobiology, Virginia Tech, Blacksburg, VA, 24061, USA.
Bishop B; Department of Chemistry and Biochemistry, George Mason University, Manassas, VA, 20110, USA.
Webb-Robertson BM; Biological Sciences Division, Pacific Northwest National Laboratory, J4-18, P.O. Box 999, Richland, WA, 99354, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Nov 06; Vol. 10 (1), pp. 19260. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Amino Acid Sequence*
Machine Learning*
Peptides*/chemistry
Peptides*/genetics
Software*
Antiviral Agents/*chemistry
Czasopismo naukowe
Tytuł :
The tetrameric structure of nucleotide-regulated pyrophosphatase and its modulation by deletion mutagenesis and ligand binding.
Autorzy :
Anashkin VA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Salminen A; Department of Biochemistry, University of Turku, Turku, Finland.
Orlov VN; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Lahti R; Department of Biochemistry, University of Turku, Turku, Finland.
Baykov AA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2020 Oct 15; Vol. 692, pp. 108537. Date of Electronic Publication: 2020 Aug 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amino Acid Sequence*
Bacterial Proteins*/chemistry
Bacterial Proteins*/genetics
Desulfitobacterium*/enzymology
Desulfitobacterium*/genetics
Inorganic Pyrophosphatase*/chemistry
Inorganic Pyrophosphatase*/genetics
Mutagenesis*
Sequence Deletion*
Catalytic Domain ; Ligands
SCR Organism :
Desulfitobacterium hafniense
Czasopismo naukowe
Tytuł :
A seven-residue deletion in PrP leads to generation of a spontaneous prion formed from C-terminal C1 fragment of PrP.
Autorzy :
Munoz-Montesino C; Université Paris-Saclay, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Université de Versailles Saint-Quentin-en-Yvelines, Virologie et Immunologie Moléculaires, Jouy-en-Josas, France.
Larkem D; Université Paris-Saclay, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Université de Versailles Saint-Quentin-en-Yvelines, Virologie et Immunologie Moléculaires, Jouy-en-Josas, France.
Barbereau C; Université Paris-Saclay, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Université de Versailles Saint-Quentin-en-Yvelines, Virologie et Immunologie Moléculaires, Jouy-en-Josas, France.
Igel-Egalon A; Université Paris-Saclay, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Université de Versailles Saint-Quentin-en-Yvelines, Virologie et Immunologie Moléculaires, Jouy-en-Josas, France.
Truchet S; Université Paris-Saclay, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Université de Versailles Saint-Quentin-en-Yvelines, Virologie et Immunologie Moléculaires, Jouy-en-Josas, France.
Jacquet E; Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France.
Nhiri N; Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France.
Moudjou M; Université Paris-Saclay, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Université de Versailles Saint-Quentin-en-Yvelines, Virologie et Immunologie Moléculaires, Jouy-en-Josas, France.
Sizun C; Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France.
Rezaei H; Université Paris-Saclay, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Université de Versailles Saint-Quentin-en-Yvelines, Virologie et Immunologie Moléculaires, Jouy-en-Josas, France.
Béringue V; Université Paris-Saclay, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Université de Versailles Saint-Quentin-en-Yvelines, Virologie et Immunologie Moléculaires, Jouy-en-Josas, France.
Dron M; Université Paris-Saclay, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Université de Versailles Saint-Quentin-en-Yvelines, Virologie et Immunologie Moléculaires, Jouy-en-Josas, France .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Oct 09; Vol. 295 (41), pp. 14025-14039. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amino Acid Sequence*
PrPSc Proteins*/chemistry
PrPSc Proteins*/genetics
PrPSc Proteins*/metabolism
Prion Diseases*/genetics
Prion Diseases*/metabolism
Prion Diseases*/pathology
Protein Aggregation, Pathological*/genetics
Protein Aggregation, Pathological*/metabolism
Protein Aggregation, Pathological*/pathology
Sequence Deletion*
Animals ; Cell Line ; Humans ; Protein Conformation, alpha-Helical ; Protein Domains ; Rabbits ; Sheep ; Solubility
Czasopismo naukowe
Tytuł :
Asparagine residue 368 is involved in Alzheimer's disease tau strain-specific aggregation.
Autorzy :
Shimonaka S; Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, Tokyo, Japan.; Department of Diagnosis, Prevention, and Treatment of Dementia, Juntendo University School of Medicine, Tokyo, Japan.
Matsumoto SE; Department of Immunology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Elahi M; Department of Diagnosis, Prevention, and Treatment of Dementia, Juntendo University School of Medicine, Tokyo, Japan.; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Ishiguro K; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Hasegawa M; Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Hattori N; Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, Tokyo, Japan.; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Motoi Y; Department of Diagnosis, Prevention, and Treatment of Dementia, Juntendo University School of Medicine, Tokyo, Japan .; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Oct 09; Vol. 295 (41), pp. 13996-14014. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alzheimer Disease*/genetics
Alzheimer Disease*/metabolism
Amino Acid Sequence*
Protein Aggregation, Pathological*/genetics
Protein Aggregation, Pathological*/metabolism
Sequence Deletion*
tau Proteins*/chemistry
tau Proteins*/genetics
tau Proteins*/metabolism
Asparagine/chemistry ; Asparagine/genetics ; Asparagine/metabolism ; Cell Line, Tumor ; Humans
Czasopismo naukowe
Tytuł :
Truncation of Tau selectively facilitates its pathological activities.
Autorzy :
Gu J; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, USA; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education of China, Nantong University, Nantong, Jiangsu, China.
Xu W; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, USA; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education of China, Nantong University, Nantong, Jiangsu, China.
Jin N; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education of China, Nantong University, Nantong, Jiangsu, China.
Li L; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, USA; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education of China, Nantong University, Nantong, Jiangsu, China.
Zhou Y; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, USA; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education of China, Nantong University, Nantong, Jiangsu, China.
Chu D; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education of China, Nantong University, Nantong, Jiangsu, China.
Gong CX; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, USA.
Iqbal K; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, USA.
Liu F; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Oct 02; Vol. 295 (40), pp. 13812-13828. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amino Acid Sequence*
Sequence Deletion*
Alzheimer Disease/*metabolism
tau Proteins/*metabolism
Alzheimer Disease/genetics ; Animals ; HEK293 Cells ; HeLa Cells ; Humans ; Mice ; Rats ; tau Proteins/genetics
Czasopismo naukowe

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